locus-tag	class	description
XcvCFBP7111P_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XcvCFBP7111P_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XcvCFBP7111P_RS00020	COG0187	DNA topoisomerase II activity
XcvCFBP7111P_RS00030	COG0501	Belongs to the peptidase M48B family
XcvCFBP7111P_RS00070	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XcvCFBP7111P_RS00080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcvCFBP7111P_RS00130	COG0793	Belongs to the peptidase S41A family
XcvCFBP7111P_RS00135	COG4942	peptidase
XcvCFBP7111P_RS00145	COG2234	aminopeptidase activity
XcvCFBP7111P_RS00155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcvCFBP7111P_RS00160	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcvCFBP7111P_RS00170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcvCFBP7111P_RS00180	COG1064	alcohol dehydrogenase
XcvCFBP7111P_RS00195	COG0493	'glutamate synthase
XcvCFBP7111P_RS00200	COG0067	glutamate synthase
XcvCFBP7111P_RS00200	COG0069	glutamate synthase activity
XcvCFBP7111P_RS00200	COG0070	glutamate synthase
XcvCFBP7111P_RS00290	COG1205	dead DEAH box helicase
XcvCFBP7111P_RS00290	COG1111	helicase
XcvCFBP7111P_RS00295	COG1272	protein, Hemolysin III
XcvCFBP7111P_RS00315	COG0300	oxidoreductase activity
XcvCFBP7111P_RS00320	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS00350	COG1733	regulation of RNA biosynthetic process
XcvCFBP7111P_RS00375	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
XcvCFBP7111P_RS00390	COG1733	regulation of RNA biosynthetic process
XcvCFBP7111P_RS00395	COG3237	CsbD-like
XcvCFBP7111P_RS00445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcvCFBP7111P_RS00455	COG0477	Major facilitator Superfamily
XcvCFBP7111P_RS00500	COG0714	Associated with various cellular activities
XcvCFBP7111P_RS00535	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XcvCFBP7111P_RS00545	COG4772	TonB-dependent receptor
XcvCFBP7111P_RS00560	COG1012	belongs to the aldehyde dehydrogenase family
XcvCFBP7111P_RS00590	COG1304	FMN binding
XcvCFBP7111P_RS00605	COG4585	Histidine kinase
XcvCFBP7111P_RS00610	COG2197	response regulator
XcvCFBP7111P_RS00630	COG3710	Transcriptional regulator
XcvCFBP7111P_RS00635	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XcvCFBP7111P_RS00760	COG0564	pseudouridine synthase activity
XcvCFBP7111P_RS00815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcvCFBP7111P_RS00825	COG4221	oxidoreductase activity
XcvCFBP7111P_RS00830	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS00840	COG0477	Major facilitator Superfamily
XcvCFBP7111P_RS00845	COG1289	transmembrane transporter activity
XcvCFBP7111P_RS00855	COG1566	PFAM secretion protein HlyD family protein
XcvCFBP7111P_RS00870	COG0302	gtp cyclohydrolase
XcvCFBP7111P_RS00890	COG0730	response to heat
XcvCFBP7111P_RS00895	COG3012	SEC-C Motif Domain Protein
XcvCFBP7111P_RS00905	COG0676	glucose-6-phosphate 1-epimerase activity
XcvCFBP7111P_RS00925	COG3135	benzoate transporter
XcvCFBP7111P_RS00955	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XcvCFBP7111P_RS00965	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XcvCFBP7111P_RS00975	COG1435	thymidine kinase activity
XcvCFBP7111P_RS00980	COG0210	DNA helicase
XcvCFBP7111P_RS00995	COG3132	Protein of unknown function, DUF480
XcvCFBP7111P_RS01005	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XcvCFBP7111P_RS01010	COG0284	orotidine-5'-phosphate decarboxylase activity
XcvCFBP7111P_RS01045	COG2937	Belongs to the GPAT DAPAT family
XcvCFBP7111P_RS01050	COG0604	alcohol dehydrogenase
XcvCFBP7111P_RS01050	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS01050	COG3321	synthase
XcvCFBP7111P_RS01085	COG2211	Major facilitator Superfamily
XcvCFBP7111P_RS01100	COG3693	PFAM glycoside hydrolase, family 10
XcvCFBP7111P_RS01115	COG1904	glucuronate isomerase
XcvCFBP7111P_RS01120	COG3250	beta-galactosidase activity
XcvCFBP7111P_RS01130	COG3386	PFAM SMP-30 Gluconolaconase
XcvCFBP7111P_RS01160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcvCFBP7111P_RS01210	COG0246	Mannitol dehydrogenase
XcvCFBP7111P_RS01215	COG1472	Belongs to the glycosyl hydrolase 3 family
XcvCFBP7111P_RS01225	COG4948	Mandelate Racemase Muconate Lactonizing
XcvCFBP7111P_RS01235	COG3661	Belongs to the glycosyl hydrolase 67 family
XcvCFBP7111P_RS01245	COG2115	Belongs to the xylose isomerase family
XcvCFBP7111P_RS01255	COG0037	tRNA processing
XcvCFBP7111P_RS01260	COG2974	May be involved in recombination
XcvCFBP7111P_RS01280	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XcvCFBP7111P_RS01290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcvCFBP7111P_RS01295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcvCFBP7111P_RS01300	COG0805	protein transport
XcvCFBP7111P_RS01310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcvCFBP7111P_RS01310	COG0519	Catalyzes the synthesis of GMP from XMP
XcvCFBP7111P_RS01315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcvCFBP7111P_RS01320	COG0752	glycyl-tRNA synthetase alpha subunit
XcvCFBP7111P_RS01330	COG0457	Tetratricopeptide repeat
XcvCFBP7111P_RS01335	COG4771	TonB-dependent receptor
XcvCFBP7111P_RS01340	COG0729	surface antigen
XcvCFBP7111P_RS01345	COG2911	Protein conserved in bacteria
XcvCFBP7111P_RS01365	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcvCFBP7111P_RS01375	COG3265	gluconokinase activity
XcvCFBP7111P_RS01380	COG2211	Major facilitator Superfamily
XcvCFBP7111P_RS01385	COG3459	Glycosyltransferase 36 associated
XcvCFBP7111P_RS01400	COG0784	Response regulator, receiver
XcvCFBP7111P_RS01400	COG2205	protein histidine kinase activity
XcvCFBP7111P_RS01405	COG1971	Probably functions as a manganese efflux pump
XcvCFBP7111P_RS01410	COG1414	Transcriptional regulator
XcvCFBP7111P_RS01415	COG0738	Major facilitator superfamily
XcvCFBP7111P_RS01420	COG3254	rhamnose metabolic process
XcvCFBP7111P_RS01425	COG4948	Mandelate Racemase Muconate Lactonizing
XcvCFBP7111P_RS01430	COG0179	Fumarylacetoacetate (FAA) hydrolase
XcvCFBP7111P_RS01435	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS01455	COG3507	Belongs to the glycosyl hydrolase 43 family
XcvCFBP7111P_RS01485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XcvCFBP7111P_RS01495	COG3162	membrane
XcvCFBP7111P_RS01500	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XcvCFBP7111P_RS01510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcvCFBP7111P_RS01520	COG1940	carbohydrate kinase activity
XcvCFBP7111P_RS01520	COG1846	Transcriptional regulator
XcvCFBP7111P_RS01525	COG0708	Exodeoxyribonuclease III
XcvCFBP7111P_RS01540	COG2091	lysine biosynthetic process via aminoadipic acid
XcvCFBP7111P_RS01550	COG3540	Alkaline phosphatase
XcvCFBP7111P_RS01555	COG0357	Ribosomal RNA small subunit methyltransferase G
XcvCFBP7111P_RS01575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7111P_RS01605	COG2159	amidohydrolase
XcvCFBP7111P_RS01620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcvCFBP7111P_RS01625	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS01630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcvCFBP7111P_RS01795	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS01800	COG0667	Aldo Keto reductase
XcvCFBP7111P_RS01825	COG0631	protein serine/threonine phosphatase activity
XcvCFBP7111P_RS01830	COG0515	serine threonine protein kinase
XcvCFBP7111P_RS01870	COG0408	coproporphyrinogen oxidase activity
XcvCFBP7111P_RS01890	COG4946	Tricorn protease homolog
XcvCFBP7111P_RS01890	COG1506	peptidase
XcvCFBP7111P_RS01890	COG0823	Involved in the tonB-independent uptake of proteins
XcvCFBP7111P_RS01915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcvCFBP7111P_RS01930	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcvCFBP7111P_RS01965	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS01975	COG0463	Glycosyl transferase, family 2
XcvCFBP7111P_RS01985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XcvCFBP7111P_RS01990	COG3100	YcgL domain-containing protein
XcvCFBP7111P_RS02005	COG3387	PFAM Glycoside hydrolase 15-related
XcvCFBP7111P_RS02010	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcvCFBP7111P_RS02030	COG2239	Acts as a magnesium transporter
XcvCFBP7111P_RS02035	COG0045	succinate-CoA ligase (ADP-forming) activity
XcvCFBP7111P_RS02035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XcvCFBP7111P_RS02035	COG1042	CoA-binding domain protein
XcvCFBP7111P_RS02050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcvCFBP7111P_RS02060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcvCFBP7111P_RS02090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XcvCFBP7111P_RS02095	COG0842	Transport permease protein
XcvCFBP7111P_RS02100	COG1131	(ABC) transporter
XcvCFBP7111P_RS02105	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcvCFBP7111P_RS02130	COG1230	cation diffusion facilitator family transporter
XcvCFBP7111P_RS02150	COG1476	TRANSCRIPTIONal
XcvCFBP7111P_RS02160	COG4555	ABC transporter
XcvCFBP7111P_RS02195	COG0625	glutathione transferase activity
XcvCFBP7111P_RS02320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XcvCFBP7111P_RS02335	COG1199	ATP-dependent helicase activity
XcvCFBP7111P_RS02510	COG0740	serine-type endopeptidase activity
XcvCFBP7111P_RS02645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcvCFBP7111P_RS02690	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XcvCFBP7111P_RS02690	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XcvCFBP7111P_RS02695	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XcvCFBP7111P_RS02715	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XcvCFBP7111P_RS02760	COG3237	CsbD-like
XcvCFBP7111P_RS02765	COG0180	Tryptophanyl-tRNA synthetase
XcvCFBP7111P_RS02790	COG0697	spore germination
XcvCFBP7111P_RS02815	COG1136	(ABC) transporter
XcvCFBP7111P_RS02820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7111P_RS02825	COG4585	Histidine kinase
XcvCFBP7111P_RS02830	COG2197	response regulator
XcvCFBP7111P_RS02845	COG0753	catalase activity
XcvCFBP7111P_RS02860	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcvCFBP7111P_RS02865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XcvCFBP7111P_RS02890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcvCFBP7111P_RS02925	COG1090	epimerase
XcvCFBP7111P_RS02960	COG1690	Belongs to the RtcB family
XcvCFBP7111P_RS03000	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XcvCFBP7111P_RS03015	COG0606	chelatase, subunit chli
XcvCFBP7111P_RS03035	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XcvCFBP7111P_RS03035	COG3291	Pkd domain containing protein
XcvCFBP7111P_RS03055	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XcvCFBP7111P_RS03060	COG1166	arginine decarboxylase activity
XcvCFBP7111P_RS03065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcvCFBP7111P_RS03075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XcvCFBP7111P_RS03075	COG2755	lipolytic protein G-D-S-L family
XcvCFBP7111P_RS03080	COG4221	oxidoreductase activity
XcvCFBP7111P_RS03095	COG0018	arginyl-trna synthetase
XcvCFBP7111P_RS03100	COG2003	Belongs to the UPF0758 family
XcvCFBP7111P_RS03105	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XcvCFBP7111P_RS03110	COG0756	dUTP diphosphatase activity
XcvCFBP7111P_RS03130	COG0463	Glycosyl transferase, family 2
XcvCFBP7111P_RS03155	COG1475	DNA binding
XcvCFBP7111P_RS03160	COG1192	Involved in chromosome partitioning
XcvCFBP7111P_RS03170	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XcvCFBP7111P_RS03175	COG0708	Exodeoxyribonuclease III
XcvCFBP7111P_RS03180	COG2211	Major facilitator Superfamily
XcvCFBP7111P_RS03190	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XcvCFBP7111P_RS03195	COG0739	heme binding
XcvCFBP7111P_RS03200	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XcvCFBP7111P_RS03245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XcvCFBP7111P_RS03260	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XcvCFBP7111P_RS03290	COG0109	protoheme IX farnesyltransferase activity
XcvCFBP7111P_RS03305	COG0358	DNA primase activity
XcvCFBP7111P_RS03310	COG1295	ribonuclease BN
XcvCFBP7111P_RS03320	COG1610	YqeY-like protein
XcvCFBP7111P_RS03330	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XcvCFBP7111P_RS03335	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XcvCFBP7111P_RS03345	COG2133	pyrroloquinoline quinone binding
XcvCFBP7111P_RS03350	COG4682	membrane
XcvCFBP7111P_RS03370	COG0531	amino acid
XcvCFBP7111P_RS03380	COG4948	Mandelate Racemase Muconate Lactonizing
XcvCFBP7111P_RS03390	COG3023	N-Acetylmuramoyl-L-alanine amidase
XcvCFBP7111P_RS03395	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XcvCFBP7111P_RS03440	COG5383	Protein conserved in bacteria
XcvCFBP7111P_RS03460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7111P_RS03465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7111P_RS03470	COG1473	amidohydrolase
XcvCFBP7111P_RS03475	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcvCFBP7111P_RS03475	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcvCFBP7111P_RS03480	COG1652	LysM domain
XcvCFBP7111P_RS03500	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS03540	COG3209	COG3209 Rhs family protein
XcvCFBP7111P_RS03580	COG3657	addiction module killer protein
XcvCFBP7111P_RS03645	COG2003	Belongs to the UPF0758 family
XcvCFBP7111P_RS03695	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XcvCFBP7111P_RS03700	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XcvCFBP7111P_RS03705	COG3118	belongs to the thioredoxin family
XcvCFBP7111P_RS03710	COG0513	Belongs to the DEAD box helicase family
XcvCFBP7111P_RS03715	COG2884	Cell division ATP-binding protein ftsE
XcvCFBP7111P_RS03720	COG2177	Part of the ABC transporter FtsEX involved in
XcvCFBP7111P_RS03725	COG3437	response regulator, receiver
XcvCFBP7111P_RS03730	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XcvCFBP7111P_RS03735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcvCFBP7111P_RS03740	COG2860	membrane
XcvCFBP7111P_RS03745	COG1252	NADH dehydrogenase
XcvCFBP7111P_RS03760	COG0625	glutathione transferase activity
XcvCFBP7111P_RS03765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XcvCFBP7111P_RS03785	COG0534	Mate efflux family protein
XcvCFBP7111P_RS03790	COG0616	signal peptide processing
XcvCFBP7111P_RS03800	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS03815	COG0009	L-threonylcarbamoyladenylate synthase
XcvCFBP7111P_RS03820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XcvCFBP7111P_RS03820	COG1754	DNA topoisomerase type I activity
XcvCFBP7111P_RS03840	COG0758	DNA mediated transformation
XcvCFBP7111P_RS03845	COG1652	LysM domain
XcvCFBP7111P_RS03850	COG0242	peptide deformylase activity
XcvCFBP7111P_RS03855	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XcvCFBP7111P_RS03860	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XcvCFBP7111P_RS03860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcvCFBP7111P_RS03915	COG1560	Kdo2-lipid A biosynthetic process
XcvCFBP7111P_RS03920	COG1490	D-aminoacyl-tRNA deacylase activity
XcvCFBP7111P_RS03925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcvCFBP7111P_RS03940	COG0582	viral genome integration into host DNA
XcvCFBP7111P_RS04025	COG0024	Methionine aminopeptidase
XcvCFBP7111P_RS04035	COG0659	secondary active sulfate transmembrane transporter activity
XcvCFBP7111P_RS04065	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcvCFBP7111P_RS04070	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS04085	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS04100	COG0251	oxidation-reduction process
XcvCFBP7111P_RS04175	COG1063	alcohol dehydrogenase
XcvCFBP7111P_RS04190	COG1132	(ABC) transporter
XcvCFBP7111P_RS04210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XcvCFBP7111P_RS04215	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS04230	COG1294	oxidase, subunit
XcvCFBP7111P_RS04235	COG1271	oxidase subunit
XcvCFBP7111P_RS04285	COG3546	catalase activity
XcvCFBP7111P_RS04290	COG3685	Protein conserved in bacteria
XcvCFBP7111P_RS04315	COG2972	Histidine kinase
XcvCFBP7111P_RS04330	COG0531	amino acid
XcvCFBP7111P_RS04345	COG3590	peptidase
XcvCFBP7111P_RS04360	COG0667	Aldo Keto reductase
XcvCFBP7111P_RS04370	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS04380	COG3384	dioxygenase
XcvCFBP7111P_RS04390	COG1573	uracil-dna glycosylase
XcvCFBP7111P_RS04395	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XcvCFBP7111P_RS04405	COG0025	NhaP-type Na H and K H
XcvCFBP7111P_RS04410	COG1131	(ABC) transporter
XcvCFBP7111P_RS04415	COG0842	Transport permease protein
XcvCFBP7111P_RS04475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcvCFBP7111P_RS04480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XcvCFBP7111P_RS04500	COG2205	protein histidine kinase activity
XcvCFBP7111P_RS04500	COG2202	Pas domain
XcvCFBP7111P_RS04520	COG2813	Specifically methylates the guanine in position
XcvCFBP7111P_RS04525	COG1187	pseudouridine synthase activity
XcvCFBP7111P_RS04530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XcvCFBP7111P_RS04555	COG5002	protein histidine kinase activity
XcvCFBP7111P_RS04555	COG2198	Histidine kinase
XcvCFBP7111P_RS04555	COG0784	Response regulator, receiver
XcvCFBP7111P_RS04565	COG1666	GTP binding
XcvCFBP7111P_RS04570	COG0697	spore germination
XcvCFBP7111P_RS04575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XcvCFBP7111P_RS04580	COG2011	ABC-type metal ion transport system permease component
XcvCFBP7111P_RS04625	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcvCFBP7111P_RS04635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcvCFBP7111P_RS04655	COG0356	it plays a direct role in the translocation of protons across the membrane
XcvCFBP7111P_RS04665	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XcvCFBP7111P_RS04670	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XcvCFBP7111P_RS04675	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XcvCFBP7111P_RS04680	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XcvCFBP7111P_RS04685	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XcvCFBP7111P_RS04690	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XcvCFBP7111P_RS04710	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XcvCFBP7111P_RS04715	COG4191	Histidine kinase
XcvCFBP7111P_RS04725	COG1136	(ABC) transporter
XcvCFBP7111P_RS04725	COG0577	efflux transmembrane transporter activity
XcvCFBP7111P_RS04735	COG1136	(ABC) transporter
XcvCFBP7111P_RS04740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7111P_RS04745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcvCFBP7111P_RS04795	COG0339	signal peptide processing
XcvCFBP7111P_RS04810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcvCFBP7111P_RS04815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XcvCFBP7111P_RS04820	COG0546	phosphoglycolate phosphatase activity
XcvCFBP7111P_RS04830	COG2819	hydrolase of the alpha beta superfamily
XcvCFBP7111P_RS04840	COG1956	GAF domain-containing protein
XcvCFBP7111P_RS04845	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XcvCFBP7111P_RS04855	COG2015	COG2015, Alkyl sulfatase and related hydrolases
XcvCFBP7111P_RS04865	COG0720	synthase
XcvCFBP7111P_RS04875	COG4771	TonB-dependent receptor
XcvCFBP7111P_RS04885	COG0513	Belongs to the DEAD box helicase family
XcvCFBP7111P_RS04900	COG0625	glutathione transferase activity
XcvCFBP7111P_RS04930	COG0626	cystathionine gamma-synthase activity
XcvCFBP7111P_RS04940	COG0438	transferase activity, transferring glycosyl groups
XcvCFBP7111P_RS04960	COG0438	transferase activity, transferring glycosyl groups
XcvCFBP7111P_RS04965	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XcvCFBP7111P_RS04980	COG2813	Specifically methylates the guanine in position
XcvCFBP7111P_RS05000	COG0463	Glycosyl transferase, family 2
XcvCFBP7111P_RS05025	COG2086	electron transfer activity
XcvCFBP7111P_RS05055	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XcvCFBP7111P_RS05055	COG0662	Cupin 2, conserved barrel domain protein
XcvCFBP7111P_RS05060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcvCFBP7111P_RS05090	COG3218	ABC-type transport auxiliary lipoprotein component
XcvCFBP7111P_RS05090	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcvCFBP7111P_RS05095	COG1127	ABC transporter
XcvCFBP7111P_RS05100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcvCFBP7111P_RS05115	COG0442	prolyl-tRNA aminoacylation
XcvCFBP7111P_RS05125	COG1183	phosphatidylcholine synthase activity
XcvCFBP7111P_RS05145	COG0741	lytic transglycosylase activity
XcvCFBP7111P_RS05160	COG0525	valine-tRNA ligase activity
XcvCFBP7111P_RS05175	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcvCFBP7111P_RS05185	COG0795	lipopolysaccharide-transporting ATPase activity
XcvCFBP7111P_RS05200	COG4974	Belongs to the 'phage' integrase family
XcvCFBP7111P_RS05215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcvCFBP7111P_RS05230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XcvCFBP7111P_RS05230	COG0047	phosphoribosylformylglycinamidine synthase activity
XcvCFBP7111P_RS05235	COG5295	Hep Hag repeat protein
XcvCFBP7111P_RS05240	COG1404	Belongs to the peptidase S8 family
XcvCFBP7111P_RS05245	COG5295	Hep Hag repeat protein
XcvCFBP7111P_RS05250	COG1404	Belongs to the peptidase S8 family
XcvCFBP7111P_RS05255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcvCFBP7111P_RS05265	COG1459	type II secretion system
XcvCFBP7111P_RS05270	COG2165	general secretion pathway protein
XcvCFBP7111P_RS05275	COG4970	Tfp pilus assembly protein FimT
XcvCFBP7111P_RS05280	COG2165	general secretion pathway protein
XcvCFBP7111P_RS05285	COG4795	General secretion pathway protein
XcvCFBP7111P_RS05290	COG3156	type II secretion system protein K
XcvCFBP7111P_RS05295	COG3166	PFAM Fimbrial assembly family protein
XcvCFBP7111P_RS05310	COG1450	Type ii and iii secretion system protein
XcvCFBP7111P_RS05320	COG2188	Transcriptional regulator
XcvCFBP7111P_RS05375	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XcvCFBP7111P_RS05390	COG1215	transferase activity, transferring glycosyl groups
XcvCFBP7111P_RS05395	COG1215	transferase activity, transferring glycosyl groups
XcvCFBP7111P_RS05400	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XcvCFBP7111P_RS05405	COG0457	Tetratricopeptide repeat
XcvCFBP7111P_RS05430	COG0242	peptide deformylase activity
XcvCFBP7111P_RS05435	COG1307	EDD domain protein, DegV family
XcvCFBP7111P_RS05460	COG0402	S-adenosylhomocysteine deaminase activity
XcvCFBP7111P_RS05465	COG3964	amidohydrolase
XcvCFBP7111P_RS05480	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcvCFBP7111P_RS05485	COG0726	polysaccharide deacetylase
XcvCFBP7111P_RS05500	COG0436	Aminotransferase
XcvCFBP7111P_RS05545	COG1162	GTPase activity
XcvCFBP7111P_RS05575	COG2211	Major facilitator Superfamily
XcvCFBP7111P_RS05580	COG1609	Transcriptional regulator
XcvCFBP7111P_RS05855	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS05860	COG2851	Citrate transporter
XcvCFBP7111P_RS05880	COG0642	Histidine kinase
XcvCFBP7111P_RS05895	COG2197	response regulator
XcvCFBP7111P_RS05910	COG0667	Aldo Keto reductase
XcvCFBP7111P_RS05920	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS05945	COG1301	dicarboxylic acid transport
XcvCFBP7111P_RS05950	COG0280	phosphate acetyltransferase
XcvCFBP7111P_RS05950	COG0281	malic enzyme
XcvCFBP7111P_RS05975	COG1560	Kdo2-lipid A biosynthetic process
XcvCFBP7111P_RS05980	COG1519	Transferase
XcvCFBP7111P_RS05985	COG1538	Outer membrane efflux protein
XcvCFBP7111P_RS05990	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcvCFBP7111P_RS06010	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XcvCFBP7111P_RS06015	COG0066	3-isopropylmalate dehydratase activity
XcvCFBP7111P_RS06020	COG0473	3-isopropylmalate dehydrogenase activity
XcvCFBP7111P_RS06025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XcvCFBP7111P_RS06045	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XcvCFBP7111P_RS06050	COG0405	Gamma-glutamyltransferase
XcvCFBP7111P_RS06055	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS06070	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XcvCFBP7111P_RS06075	COG3710	Transcriptional regulator
XcvCFBP7111P_RS06095	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XcvCFBP7111P_RS06105	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XcvCFBP7111P_RS06120	COG0563	adenylate kinase activity
XcvCFBP7111P_RS06125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcvCFBP7111P_RS06135	COG3781	membrane
XcvCFBP7111P_RS06140	COG0671	phosphoesterase, PA-phosphatase related
XcvCFBP7111P_RS06150	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS06155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcvCFBP7111P_RS06160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XcvCFBP7111P_RS06190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcvCFBP7111P_RS06205	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcvCFBP7111P_RS06225	COG0352	thiamine-phosphate diphosphorylase activity
XcvCFBP7111P_RS06230	COG1773	rubredoxin
XcvCFBP7111P_RS06235	COG2912	Transglutaminase-like superfamily
XcvCFBP7111P_RS06245	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XcvCFBP7111P_RS06255	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XcvCFBP7111P_RS06275	COG3079	Belongs to the UPF0149 family
XcvCFBP7111P_RS06280	COG0006	proline dipeptidase activity
XcvCFBP7111P_RS06290	COG0006	proline dipeptidase activity
XcvCFBP7111P_RS06305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XcvCFBP7111P_RS06310	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XcvCFBP7111P_RS06320	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XcvCFBP7111P_RS06325	COG1561	YicC-like family, N-terminal region
XcvCFBP7111P_RS06340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcvCFBP7111P_RS06345	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS06360	COG2271	Major facilitator Superfamily
XcvCFBP7111P_RS06375	COG2721	sulfolactate sulfo-lyase activity
XcvCFBP7111P_RS06385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XcvCFBP7111P_RS06410	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XcvCFBP7111P_RS06440	COG0714	Associated with various cellular activities
XcvCFBP7111P_RS06460	COG2304	oxidoreductase activity
XcvCFBP7111P_RS06470	COG1301	dicarboxylic acid transport
XcvCFBP7111P_RS06475	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XcvCFBP7111P_RS06485	COG4773	Receptor
XcvCFBP7111P_RS06490	COG0739	heme binding
XcvCFBP7111P_RS06495	COG1376	ErfK ybiS ycfS ynhG family protein
XcvCFBP7111P_RS06530	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XcvCFBP7111P_RS06535	COG4149	molybdate abc transporter
XcvCFBP7111P_RS06540	COG0725	ABC transporter, periplasmic molybdate-binding protein
XcvCFBP7111P_RS06545	COG3453	Protein conserved in bacteria
XcvCFBP7111P_RS06545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcvCFBP7111P_RS06555	COG3047	cAMP biosynthetic process
XcvCFBP7111P_RS06570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XcvCFBP7111P_RS06595	COG0126	phosphoglycerate kinase activity
XcvCFBP7111P_RS06605	COG0469	pyruvate kinase activity
XcvCFBP7111P_RS06615	COG3588	fructose-bisphosphate aldolase
XcvCFBP7111P_RS06620	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XcvCFBP7111P_RS06635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcvCFBP7111P_RS06635	COG1648	precorrin-2 dehydrogenase activity
XcvCFBP7111P_RS06655	COG2205	protein histidine kinase activity
XcvCFBP7111P_RS06655	COG2198	Histidine kinase
XcvCFBP7111P_RS06655	COG0784	Response regulator, receiver
XcvCFBP7111P_RS06675	COG0175	sulfate reduction
XcvCFBP7111P_RS06680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XcvCFBP7111P_RS06685	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcvCFBP7111P_RS06690	COG0175	sulfate reduction
XcvCFBP7111P_RS06695	COG0529	Catalyzes the synthesis of activated sulfate
XcvCFBP7111P_RS06695	COG2895	sulfate adenylyltransferase (ATP) activity
XcvCFBP7111P_RS06705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7111P_RS06710	COG0308	aminopeptidase N
XcvCFBP7111P_RS06720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcvCFBP7111P_RS06730	COG4948	Mandelate Racemase Muconate Lactonizing
XcvCFBP7111P_RS06735	COG3250	beta-galactosidase activity
XcvCFBP7111P_RS06745	COG1609	Transcriptional regulator
XcvCFBP7111P_RS06755	COG1970	mechanosensitive ion channel activity
XcvCFBP7111P_RS06780	COG0471	metal ion transport
XcvCFBP7111P_RS06780	COG3273	potassium ion transport
XcvCFBP7111P_RS06785	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XcvCFBP7111P_RS06790	COG2022	thiamine diphosphate biosynthetic process
XcvCFBP7111P_RS06840	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
XcvCFBP7111P_RS06840	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
XcvCFBP7111P_RS06880	COG2003	Belongs to the UPF0758 family
XcvCFBP7111P_RS06995	COG0189	ligase activity
XcvCFBP7111P_RS07005	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7111P_RS07055	COG0237	dephospho-CoA kinase activity
XcvCFBP7111P_RS07060	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XcvCFBP7111P_RS07075	COG4969	Belongs to the N-Me-Phe pilin family
XcvCFBP7111P_RS07095	COG0045	succinate-CoA ligase (ADP-forming) activity
XcvCFBP7111P_RS07100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XcvCFBP7111P_RS07115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcvCFBP7111P_RS07115	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XcvCFBP7111P_RS07125	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcvCFBP7111P_RS07130	COG0564	pseudouridine synthase activity
XcvCFBP7111P_RS07145	COG3011	Protein conserved in bacteria
XcvCFBP7111P_RS07150	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS07170	COG3387	PFAM Glycoside hydrolase 15-related
XcvCFBP7111P_RS07175	COG1877	trehalose-phosphatase activity
XcvCFBP7111P_RS07215	COG2827	Endonuclease containing a URI domain
XcvCFBP7111P_RS07220	COG4771	TonB-dependent receptor
XcvCFBP7111P_RS07225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcvCFBP7111P_RS07230	COG0667	Aldo Keto reductase
XcvCFBP7111P_RS07235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XcvCFBP7111P_RS07240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcvCFBP7111P_RS07245	COG1116	anion transmembrane transporter activity
XcvCFBP7111P_RS07255	COG0542	response to heat
XcvCFBP7111P_RS07260	COG4206	TonB-dependent receptor
XcvCFBP7111P_RS07285	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcvCFBP7111P_RS07295	COG1492	cobalamin metabolic process
XcvCFBP7111P_RS07305	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XcvCFBP7111P_RS07325	COG0019	diaminopimelate decarboxylase activity
XcvCFBP7111P_RS07340	COG4264	IucA IucC family
XcvCFBP7111P_RS07350	COG4772	TonB-dependent receptor
XcvCFBP7111P_RS07360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcvCFBP7111P_RS07360	COG4651	solute:proton antiporter activity
XcvCFBP7111P_RS07400	COG0488	(ABC) transporter
XcvCFBP7111P_RS07440	COG0477	Major facilitator Superfamily
XcvCFBP7111P_RS07455	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XcvCFBP7111P_RS07470	COG0217	transcriptional regulatory protein
XcvCFBP7111P_RS07475	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XcvCFBP7111P_RS07480	COG0632	four-way junction helicase activity
XcvCFBP7111P_RS07485	COG3158	transport of potassium into the cell
XcvCFBP7111P_RS07495	COG2255	four-way junction helicase activity
XcvCFBP7111P_RS07500	COG0824	Thioesterase
XcvCFBP7111P_RS07510	COG0848	biopolymer transport protein
XcvCFBP7111P_RS07520	COG0823	Involved in the tonB-independent uptake of proteins
XcvCFBP7111P_RS07525	COG2885	chlorophyll binding
XcvCFBP7111P_RS07535	COG0602	queuosine metabolic process
XcvCFBP7111P_RS07545	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XcvCFBP7111P_RS07570	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS07610	COG0514	ATP-dependent DNA helicase (RecQ)
XcvCFBP7111P_RS07615	COG0783	Belongs to the Dps family
XcvCFBP7111P_RS07620	COG1643	Atp-dependent helicase
XcvCFBP7111P_RS07635	COG0837	glucose binding
XcvCFBP7111P_RS07650	COG0535	radical SAM domain protein
XcvCFBP7111P_RS07655	COG0535	radical SAM domain protein
XcvCFBP7111P_RS07660	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XcvCFBP7111P_RS07665	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XcvCFBP7111P_RS07675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcvCFBP7111P_RS07690	COG1442	glycosyl transferase family 8
XcvCFBP7111P_RS07690	COG1216	Glycosyl transferase, family 2
XcvCFBP7111P_RS07695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcvCFBP7111P_RS07705	COG1199	ATP-dependent helicase activity
XcvCFBP7111P_RS07715	COG1397	ADP-ribosylglycohydrolase
XcvCFBP7111P_RS07725	COG0189	ligase activity
XcvCFBP7111P_RS07740	COG0835	chemotaxis
XcvCFBP7111P_RS07745	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS07750	COG2198	Histidine kinase
XcvCFBP7111P_RS07750	COG0784	Response regulator, receiver
XcvCFBP7111P_RS07750	COG0643	Histidine kinase
XcvCFBP7111P_RS07775	COG1446	asparaginase
XcvCFBP7111P_RS07780	COG3142	Participates in the control of copper homeostasis
XcvCFBP7111P_RS07820	COG3537	Alpha-1,2-mannosidase
XcvCFBP7111P_RS07830	COG1486	melibiose metabolic process
XcvCFBP7111P_RS07840	COG0531	amino acid
XcvCFBP7111P_RS07855	COG1472	Belongs to the glycosyl hydrolase 3 family
XcvCFBP7111P_RS07870	COG1388	LysM domain
XcvCFBP7111P_RS07870	COG3858	chitin binding
XcvCFBP7111P_RS07885	COG0837	glucose binding
XcvCFBP7111P_RS07890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XcvCFBP7111P_RS07900	COG0494	nUDIX hydrolase
XcvCFBP7111P_RS07905	COG1218	3'(2'),5'-bisphosphate nucleotidase
XcvCFBP7111P_RS07910	COG3956	TIGRFAM MazG family protein
XcvCFBP7111P_RS07915	COG1742	UPF0060 membrane protein
XcvCFBP7111P_RS07930	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XcvCFBP7111P_RS07935	COG0509	glycine decarboxylation via glycine cleavage system
XcvCFBP7111P_RS07965	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7111P_RS07975	COG1309	transcriptional regulator
XcvCFBP7111P_RS07980	COG4771	TonB-dependent receptor
XcvCFBP7111P_RS07990	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XcvCFBP7111P_RS07995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcvCFBP7111P_RS08000	COG0463	Glycosyl transferase, family 2
XcvCFBP7111P_RS08005	COG0516	GMP reductase activity
XcvCFBP7111P_RS08005	COG0517	IMP dehydrogenase activity
XcvCFBP7111P_RS08010	COG2982	Protein involved in outer membrane biogenesis
XcvCFBP7111P_RS08015	COG1272	protein, Hemolysin III
XcvCFBP7111P_RS08020	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XcvCFBP7111P_RS08025	COG0739	heme binding
XcvCFBP7111P_RS08030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcvCFBP7111P_RS08035	COG0626	cystathionine gamma-synthase activity
XcvCFBP7111P_RS08040	COG0527	aspartate kinase activity
XcvCFBP7111P_RS08040	COG0460	homoserine dehydrogenase
XcvCFBP7111P_RS08055	COG1760	l-serine dehydratase
XcvCFBP7111P_RS08075	COG2353	YceI-like domain
XcvCFBP7111P_RS08080	COG0784	Response regulator, receiver
XcvCFBP7111P_RS08080	COG2198	Histidine kinase
XcvCFBP7111P_RS08080	COG2205	protein histidine kinase activity
XcvCFBP7111P_RS08085	COG2198	Histidine kinase
XcvCFBP7111P_RS08085	COG0784	Response regulator, receiver
XcvCFBP7111P_RS08085	COG5002	protein histidine kinase activity
XcvCFBP7111P_RS08100	COG2814	Major facilitator Superfamily
XcvCFBP7111P_RS08105	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XcvCFBP7111P_RS08115	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XcvCFBP7111P_RS08120	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XcvCFBP7111P_RS08125	COG0259	pyridoxamine-phosphate oxidase activity
XcvCFBP7111P_RS08135	COG1842	Phage shock protein A
XcvCFBP7111P_RS08160	COG0754	glutathionylspermidine amidase activity
XcvCFBP7111P_RS08170	COG2814	Major facilitator Superfamily
XcvCFBP7111P_RS08275	COG0531	amino acid
XcvCFBP7111P_RS08280	COG2197	response regulator
XcvCFBP7111P_RS08310	COG1113	amino acid transport
XcvCFBP7111P_RS08320	COG1271	oxidase subunit
XcvCFBP7111P_RS08325	COG1294	oxidase, subunit
XcvCFBP7111P_RS08335	COG2239	Acts as a magnesium transporter
XcvCFBP7111P_RS08345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcvCFBP7111P_RS08350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcvCFBP7111P_RS08360	COG1660	Displays ATPase and GTPase activities
XcvCFBP7111P_RS08365	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XcvCFBP7111P_RS08370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcvCFBP7111P_RS08385	COG1137	ATPase activity
XcvCFBP7111P_RS08390	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XcvCFBP7111P_RS08400	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XcvCFBP7111P_RS08410	COG0271	Belongs to the BolA IbaG family
XcvCFBP7111P_RS08415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XcvCFBP7111P_RS08435	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XcvCFBP7111P_RS08445	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XcvCFBP7111P_RS08455	COG0628	permease
XcvCFBP7111P_RS08475	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XcvCFBP7111P_RS08480	COG3178	'Phosphotransferase
XcvCFBP7111P_RS08495	COG1555	photosystem II stabilization
XcvCFBP7111P_RS08505	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcvCFBP7111P_RS08510	COG1477	protein flavinylation
XcvCFBP7111P_RS08535	COG3128	pkhd-type hydroxylase
XcvCFBP7111P_RS08540	COG4774	siderophore transport
XcvCFBP7111P_RS08545	COG2146	nitrite reductase [NAD(P)H] activity
XcvCFBP7111P_RS08555	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XcvCFBP7111P_RS08560	COG0719	Fe-S assembly protein
XcvCFBP7111P_RS08565	COG0396	ATPase activity
XcvCFBP7111P_RS08570	COG0719	Fe-S assembly protein
XcvCFBP7111P_RS08575	COG1959	2 iron, 2 sulfur cluster binding
XcvCFBP7111P_RS08585	COG0693	protein deglycase activity
XcvCFBP7111P_RS08605	COG0739	heme binding
XcvCFBP7111P_RS08620	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XcvCFBP7111P_RS08655	COG1678	Uncharacterized ACR, COG1678
XcvCFBP7111P_RS08660	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XcvCFBP7111P_RS08665	COG0540	Belongs to the ATCase OTCase family
XcvCFBP7111P_RS08670	COG1764	response to oxidative stress
XcvCFBP7111P_RS08680	COG0384	phenazine biosynthesis protein PhzF
XcvCFBP7111P_RS08685	COG0384	phenazine biosynthesis protein PhzF
XcvCFBP7111P_RS08690	COG0527	aspartate kinase activity
XcvCFBP7111P_RS08705	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XcvCFBP7111P_RS08720	COG0142	geranyltranstransferase activity
XcvCFBP7111P_RS08725	COG0629	single-stranded DNA binding
XcvCFBP7111P_RS08735	COG3321	synthase
XcvCFBP7111P_RS08735	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS08735	COG0604	alcohol dehydrogenase
XcvCFBP7111P_RS08740	COG2080	2 iron, 2 sulfur cluster binding
XcvCFBP7111P_RS08745	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcvCFBP7111P_RS08750	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcvCFBP7111P_RS08755	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XcvCFBP7111P_RS08805	COG2879	small protein
XcvCFBP7111P_RS08810	COG1966	Carbon starvation protein
XcvCFBP7111P_RS08815	COG1741	Belongs to the pirin family
XcvCFBP7111P_RS08830	COG1741	Belongs to the pirin family
XcvCFBP7111P_RS08840	COG1515	deoxyribonuclease V activity
XcvCFBP7111P_RS08845	COG0588	phosphoglycerate mutase activity
XcvCFBP7111P_RS08855	COG3590	peptidase
XcvCFBP7111P_RS08860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcvCFBP7111P_RS08865	COG2201	protein-glutamate methylesterase activity
XcvCFBP7111P_RS08870	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcvCFBP7111P_RS08875	COG2200	EAL domain
XcvCFBP7111P_RS08875	COG2202	Pas domain
XcvCFBP7111P_RS08875	COG2199	diguanylate cyclase activity
XcvCFBP7111P_RS08880	COG0835	chemotaxis
XcvCFBP7111P_RS08885	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS08890	COG0643	Histidine kinase
XcvCFBP7111P_RS08890	COG2198	Histidine kinase
XcvCFBP7111P_RS08900	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XcvCFBP7111P_RS08915	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XcvCFBP7111P_RS08920	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7111P_RS08925	COG2205	protein histidine kinase activity
XcvCFBP7111P_RS08935	COG4452	Inner membrane protein CreD
XcvCFBP7111P_RS08960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcvCFBP7111P_RS08965	COG0735	belongs to the Fur family
XcvCFBP7111P_RS08980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7111P_RS08990	COG1309	transcriptional regulator
XcvCFBP7111P_RS09000	COG2207	Transcriptional regulator
XcvCFBP7111P_RS09010	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS09015	COG2814	Major facilitator Superfamily
XcvCFBP7111P_RS09020	COG0667	Aldo Keto reductase
XcvCFBP7111P_RS09080	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XcvCFBP7111P_RS09120	COG1595	DNA-templated transcription, initiation
XcvCFBP7111P_RS09130	COG5002	protein histidine kinase activity
XcvCFBP7111P_RS09130	COG5001	Diguanylate cyclase
XcvCFBP7111P_RS09135	COG1187	pseudouridine synthase activity
XcvCFBP7111P_RS09160	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcvCFBP7111P_RS09170	COG0475	glutathione-regulated potassium exporter activity
XcvCFBP7111P_RS09175	COG5000	phosphorelay sensor kinase activity
XcvCFBP7111P_RS09175	COG5002	protein histidine kinase activity
XcvCFBP7111P_RS09180	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7111P_RS09185	COG1538	Outer membrane efflux protein
XcvCFBP7111P_RS09210	COG1132	(ABC) transporter
XcvCFBP7111P_RS09255	COG2155	Conserved Protein
XcvCFBP7111P_RS09285	COG3118	belongs to the thioredoxin family
XcvCFBP7111P_RS09295	COG0495	leucyl-tRNA aminoacylation
XcvCFBP7111P_RS09310	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XcvCFBP7111P_RS09325	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XcvCFBP7111P_RS09340	COG2968	Membrane
XcvCFBP7111P_RS09345	COG0424	maF-like protein
XcvCFBP7111P_RS09355	COG3164	Protein of unknown function
XcvCFBP7111P_RS09365	COG0312	modulator of DNA gyrase
XcvCFBP7111P_RS09370	COG3028	Belongs to the UPF0307 family
XcvCFBP7111P_RS09375	COG0312	modulator of DNA gyrase
XcvCFBP7111P_RS09385	COG4104	PAAR repeat-containing protein
XcvCFBP7111P_RS09390	COG0142	geranyltranstransferase activity
XcvCFBP7111P_RS09395	COG1722	exodeoxyribonuclease VII activity
XcvCFBP7111P_RS09400	COG0037	tRNA processing
XcvCFBP7111P_RS09410	COG1785	Belongs to the alkaline phosphatase family
XcvCFBP7111P_RS09415	COG1301	dicarboxylic acid transport
XcvCFBP7111P_RS09420	COG4106	trans-aconitate 2-methyltransferase activity
XcvCFBP7111P_RS09430	COG0791	NLP P60 protein
XcvCFBP7111P_RS09435	COG0791	NLP P60 protein
XcvCFBP7111P_RS09440	COG1047	Peptidyl-prolyl cis-trans
XcvCFBP7111P_RS09445	COG2311	Membrane
XcvCFBP7111P_RS09450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcvCFBP7111P_RS09455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcvCFBP7111P_RS09475	COG3590	peptidase
XcvCFBP7111P_RS09480	COG3590	peptidase
XcvCFBP7111P_RS09495	COG4206	TonB-dependent receptor
XcvCFBP7111P_RS09500	COG0489	protein tyrosine kinase activity
XcvCFBP7111P_RS09510	COG0717	Belongs to the dCTP deaminase family
XcvCFBP7111P_RS09540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcvCFBP7111P_RS09545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcvCFBP7111P_RS09565	COG0494	nUDIX hydrolase
XcvCFBP7111P_RS09570	COG0433	COG0433 Predicted ATPase
XcvCFBP7111P_RS09585	COG0688	phosphatidylethanolamine metabolic process
XcvCFBP7111P_RS09595	COG2890	protein-(glutamine-N5) methyltransferase activity
XcvCFBP7111P_RS09600	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XcvCFBP7111P_RS09605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XcvCFBP7111P_RS09610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XcvCFBP7111P_RS09625	COG0101	tRNA pseudouridine synthase activity
XcvCFBP7111P_RS09630	COG0135	phosphoribosylanthranilate isomerase activity
XcvCFBP7111P_RS09640	COG0133	tryptophan synthase activity
XcvCFBP7111P_RS09650	COG0159	tryptophan synthase activity
XcvCFBP7111P_RS09655	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XcvCFBP7111P_RS09660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcvCFBP7111P_RS09690	COG0300	oxidoreductase activity
XcvCFBP7111P_RS09695	COG0149	triose-phosphate isomerase activity
XcvCFBP7111P_RS09710	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcvCFBP7111P_RS09715	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcvCFBP7111P_RS09720	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcvCFBP7111P_RS09725	COG0649	NAD binding
XcvCFBP7111P_RS09730	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XcvCFBP7111P_RS09735	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XcvCFBP7111P_RS09745	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XcvCFBP7111P_RS09750	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcvCFBP7111P_RS09775	COG1007	ATP synthesis coupled electron transport
XcvCFBP7111P_RS09785	COG0779	Required for maturation of 30S ribosomal subunits
XcvCFBP7111P_RS09790	COG0195	Participates in both transcription termination and antitermination
XcvCFBP7111P_RS09795	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XcvCFBP7111P_RS09800	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XcvCFBP7111P_RS09805	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XcvCFBP7111P_RS09810	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XcvCFBP7111P_RS09815	COG1185	polyribonucleotide nucleotidyltransferase activity
XcvCFBP7111P_RS09850	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcvCFBP7111P_RS09860	COG2095	MarC family integral membrane protein
XcvCFBP7111P_RS09875	COG1611	Belongs to the LOG family
XcvCFBP7111P_RS09920	COG4969	Belongs to the N-Me-Phe pilin family
XcvCFBP7111P_RS09925	COG0556	nucleotide-excision repair
XcvCFBP7111P_RS09940	COG3505	Type IV secretory pathway VirD4
XcvCFBP7111P_RS09960	COG2948	multi-organism process
XcvCFBP7111P_RS09980	COG3702	type iv secretory pathway
XcvCFBP7111P_RS09990	COG0366	Alpha amylase catalytic
XcvCFBP7111P_RS10005	COG1082	Xylose isomerase domain protein TIM barrel
XcvCFBP7111P_RS10015	COG2211	Major facilitator Superfamily
XcvCFBP7111P_RS10015	COG2190	(PTS) system
XcvCFBP7111P_RS10030	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XcvCFBP7111P_RS10035	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XcvCFBP7111P_RS10050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XcvCFBP7111P_RS10055	COG0072	phenylalanine-tRNA ligase activity
XcvCFBP7111P_RS10055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcvCFBP7111P_RS10105	COG0438	transferase activity, transferring glycosyl groups
XcvCFBP7111P_RS10110	COG0438	transferase activity, transferring glycosyl groups
XcvCFBP7111P_RS10120	COG0438	transferase activity, transferring glycosyl groups
XcvCFBP7111P_RS10145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcvCFBP7111P_RS10150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcvCFBP7111P_RS10155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcvCFBP7111P_RS10175	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XcvCFBP7111P_RS10185	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7111P_RS10195	COG3040	lipid binding
XcvCFBP7111P_RS10205	COG0582	viral genome integration into host DNA
XcvCFBP7111P_RS10405	COG0616	signal peptide processing
XcvCFBP7111P_RS10470	COG1196	nuclear chromosome segregation
XcvCFBP7111P_RS10545	COG0322	excinuclease ABC activity
XcvCFBP7111P_RS10560	COG0784	Response regulator, receiver
XcvCFBP7111P_RS10560	COG4191	Histidine kinase
XcvCFBP7111P_RS10565	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XcvCFBP7111P_RS10570	COG1194	a g-specific adenine glycosylase
XcvCFBP7111P_RS10580	COG0552	protein localization to endoplasmic reticulum
XcvCFBP7111P_RS10590	COG3938	Belongs to the proline racemase family
XcvCFBP7111P_RS10595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcvCFBP7111P_RS10610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcvCFBP7111P_RS10620	COG0006	proline dipeptidase activity
XcvCFBP7111P_RS10635	COG0531	amino acid
XcvCFBP7111P_RS10725	COG0326	Molecular chaperone. Has ATPase activity
XcvCFBP7111P_RS10730	COG0742	ribosomal rna small subunit methyltransferase
XcvCFBP7111P_RS10735	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XcvCFBP7111P_RS10750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XcvCFBP7111P_RS10760	COG3291	Pkd domain containing protein
XcvCFBP7111P_RS10765	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XcvCFBP7111P_RS10800	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XcvCFBP7111P_RS10805	COG0343	queuine tRNA-ribosyltransferase activity
XcvCFBP7111P_RS10810	COG1862	Preprotein translocase
XcvCFBP7111P_RS10820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XcvCFBP7111P_RS10865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcvCFBP7111P_RS10865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcvCFBP7111P_RS10870	COG1105	Belongs to the carbohydrate kinase PfkB family
XcvCFBP7111P_RS10875	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcvCFBP7111P_RS10875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcvCFBP7111P_RS10885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7111P_RS10890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7111P_RS10900	COG2902	Dehydrogenase
XcvCFBP7111P_RS10905	COG0477	Major facilitator Superfamily
XcvCFBP7111P_RS10920	COG5002	protein histidine kinase activity
XcvCFBP7111P_RS10920	COG2205	protein histidine kinase activity
XcvCFBP7111P_RS10920	COG0784	Response regulator, receiver
XcvCFBP7111P_RS10925	COG2733	membrane
XcvCFBP7111P_RS10935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XcvCFBP7111P_RS10945	COG2223	nitrite transmembrane transporter activity
XcvCFBP7111P_RS10950	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XcvCFBP7111P_RS10955	COG0243	molybdopterin cofactor binding
XcvCFBP7111P_RS10970	COG0477	Major facilitator Superfamily
XcvCFBP7111P_RS10975	COG2703	oxygen carrier activity
XcvCFBP7111P_RS10985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcvCFBP7111P_RS10995	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XcvCFBP7111P_RS11010	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XcvCFBP7111P_RS11030	COG3842	ATPase activity
XcvCFBP7111P_RS11040	COG1176	ABC-type spermidine putrescine transport system, permease component I
XcvCFBP7111P_RS11045	COG1177	transmembrane transport
XcvCFBP7111P_RS11050	COG1012	belongs to the aldehyde dehydrogenase family
XcvCFBP7111P_RS11065	COG4535	Mg2 and Co2 transporter CorC
XcvCFBP7111P_RS11075	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XcvCFBP7111P_RS11085	COG1702	phosphate starvation-inducible protein PhoH
XcvCFBP7111P_RS11090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcvCFBP7111P_RS11105	COG0741	lytic transglycosylase activity
XcvCFBP7111P_RS11115	COG0723	plastoquinol--plastocyanin reductase activity
XcvCFBP7111P_RS11120	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XcvCFBP7111P_RS11125	COG2857	Cytochrome c1
XcvCFBP7111P_RS11130	COG0625	glutathione transferase activity
XcvCFBP7111P_RS11135	COG2969	positive regulation of protein catabolic process
XcvCFBP7111P_RS11155	COG1201	RNA secondary structure unwinding
XcvCFBP7111P_RS11160	COG2094	Belongs to the DNA glycosylase MPG family
XcvCFBP7111P_RS11165	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS11170	COG0835	chemotaxis
XcvCFBP7111P_RS11215	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcvCFBP7111P_RS11230	COG1570	exodeoxyribonuclease VII activity
XcvCFBP7111P_RS11235	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcvCFBP7111P_RS11240	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcvCFBP7111P_RS11240	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XcvCFBP7111P_RS11245	COG0802	atpase or kinase
XcvCFBP7111P_RS11250	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcvCFBP7111P_RS11255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XcvCFBP7111P_RS11280	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS11285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcvCFBP7111P_RS11290	COG0501	Belongs to the peptidase M48B family
XcvCFBP7111P_RS11300	COG2081	HI0933 family
XcvCFBP7111P_RS11305	COG4681	YaeQ
XcvCFBP7111P_RS11315	COG0625	glutathione transferase activity
XcvCFBP7111P_RS11325	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XcvCFBP7111P_RS11330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XcvCFBP7111P_RS11335	COG0513	Belongs to the DEAD box helicase family
XcvCFBP7111P_RS11340	COG0488	(ABC) transporter
XcvCFBP7111P_RS11360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XcvCFBP7111P_RS11365	COG0483	inositol monophosphate 1-phosphatase activity
XcvCFBP7111P_RS11380	COG3300	MHYT domain
XcvCFBP7111P_RS11380	COG5001	Diguanylate cyclase
XcvCFBP7111P_RS11385	COG1509	lysine 2,3-aminomutase activity
XcvCFBP7111P_RS11390	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcvCFBP7111P_RS11400	COG0402	S-adenosylhomocysteine deaminase activity
XcvCFBP7111P_RS11405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XcvCFBP7111P_RS11420	COG4677	pectinesterase activity
XcvCFBP7111P_RS11445	COG4302	ethanolamine ammonia-lyase activity
XcvCFBP7111P_RS11465	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XcvCFBP7111P_RS11470	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XcvCFBP7111P_RS11485	COG2166	iron-sulfur cluster assembly
XcvCFBP7111P_RS11490	COG0215	cysteine-tRNA ligase activity
XcvCFBP7111P_RS11500	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XcvCFBP7111P_RS11505	COG0137	argininosuccinate synthase activity
XcvCFBP7111P_RS11515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcvCFBP7111P_RS11520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XcvCFBP7111P_RS11530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XcvCFBP7111P_RS11535	COG0165	Argininosuccinate lyase
XcvCFBP7111P_RS11545	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XcvCFBP7111P_RS11550	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XcvCFBP7111P_RS11580	COG1294	oxidase, subunit
XcvCFBP7111P_RS11590	COG4988	ABC transporter
XcvCFBP7111P_RS11595	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XcvCFBP7111P_RS11605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcvCFBP7111P_RS11625	COG1138	Cytochrome C-type biogenesis protein
XcvCFBP7111P_RS11630	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcvCFBP7111P_RS11650	COG4133	protoheme IX ABC transporter activity
XcvCFBP7111P_RS11655	COG0436	Aminotransferase
XcvCFBP7111P_RS11675	COG1187	pseudouridine synthase activity
XcvCFBP7111P_RS11680	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XcvCFBP7111P_RS11685	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XcvCFBP7111P_RS11690	COG2350	Protein conserved in bacteria
XcvCFBP7111P_RS11720	COG1175	transmembrane transport
XcvCFBP7111P_RS11725	COG0395	ABC-type sugar transport system, permease component
XcvCFBP7111P_RS11750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcvCFBP7111P_RS11755	COG2957	Belongs to the agmatine deiminase family
XcvCFBP7111P_RS11775	COG0539	negative regulation of cytoplasmic translation
XcvCFBP7111P_RS11780	COG0776	regulation of translation
XcvCFBP7111P_RS11790	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XcvCFBP7111P_RS11795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcvCFBP7111P_RS11805	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XcvCFBP7111P_RS11815	COG0475	glutathione-regulated potassium exporter activity
XcvCFBP7111P_RS11815	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcvCFBP7111P_RS11830	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XcvCFBP7111P_RS11840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcvCFBP7111P_RS11840	COG0519	Catalyzes the synthesis of GMP from XMP
XcvCFBP7111P_RS11845	COG3002	Belongs to the UPF0753 family
XcvCFBP7111P_RS11850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcvCFBP7111P_RS11855	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS11870	COG2197	response regulator
XcvCFBP7111P_RS11885	COG1335	isochorismatase
XcvCFBP7111P_RS11900	COG2814	Major facilitator Superfamily
XcvCFBP7111P_RS11915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcvCFBP7111P_RS11915	COG1648	precorrin-2 dehydrogenase activity
XcvCFBP7111P_RS11920	COG0243	molybdopterin cofactor binding
XcvCFBP7111P_RS11935	COG3685	Protein conserved in bacteria
XcvCFBP7111P_RS11955	COG5001	Diguanylate cyclase
XcvCFBP7111P_RS11965	COG4566	intracellular signal transduction
XcvCFBP7111P_RS12005	COG3275	phosphorelay sensor kinase activity
XcvCFBP7111P_RS12010	COG3279	Response regulator of the LytR AlgR family
XcvCFBP7111P_RS12040	COG1238	metal cluster binding
XcvCFBP7111P_RS12050	COG3920	Histidine kinase
XcvCFBP7111P_RS12075	COG3220	belongs to the UPF0276 family
XcvCFBP7111P_RS12135	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS12150	COG2963	transposase activity
XcvCFBP7111P_RS12185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcvCFBP7111P_RS12185	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS12185	COG3321	synthase
XcvCFBP7111P_RS12185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcvCFBP7111P_RS12185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcvCFBP7111P_RS12190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcvCFBP7111P_RS12190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcvCFBP7111P_RS12190	COG3321	synthase
XcvCFBP7111P_RS12190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcvCFBP7111P_RS12190	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS12195	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS12195	COG4221	oxidoreductase activity
XcvCFBP7111P_RS12195	COG3321	synthase
XcvCFBP7111P_RS12195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcvCFBP7111P_RS12200	COG0300	oxidoreductase activity
XcvCFBP7111P_RS12200	COG3321	synthase
XcvCFBP7111P_RS12200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcvCFBP7111P_RS12200	COG4221	oxidoreductase activity
XcvCFBP7111P_RS12205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcvCFBP7111P_RS12205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcvCFBP7111P_RS12205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcvCFBP7111P_RS12205	COG3321	synthase
XcvCFBP7111P_RS12205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcvCFBP7111P_RS12205	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS12205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcvCFBP7111P_RS12205	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS12205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcvCFBP7111P_RS12205	COG3321	synthase
XcvCFBP7111P_RS12210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XcvCFBP7111P_RS12215	COG1136	(ABC) transporter
XcvCFBP7111P_RS12380	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS12385	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcvCFBP7111P_RS12390	COG1073	alpha beta
XcvCFBP7111P_RS12390	COG2226	methyltransferase
XcvCFBP7111P_RS12465	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XcvCFBP7111P_RS12535	COG0316	Belongs to the HesB IscA family
XcvCFBP7111P_RS12535	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XcvCFBP7111P_RS12540	COG2154	pterin-4-alpha-carbinolamine dehydratase
XcvCFBP7111P_RS12550	COG0428	transporter
XcvCFBP7111P_RS12555	COG3064	Membrane
XcvCFBP7111P_RS12565	COG1530	ribonuclease E activity
XcvCFBP7111P_RS12575	COG1054	Belongs to the UPF0176 family
XcvCFBP7111P_RS12595	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XcvCFBP7111P_RS12650	COG5599	Phosphatase
XcvCFBP7111P_RS12715	COG0629	single-stranded DNA binding
XcvCFBP7111P_RS12720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XcvCFBP7111P_RS12725	COG0270	DNA (cytosine-5-)-methyltransferase activity
XcvCFBP7111P_RS12920	COG2003	Belongs to the UPF0758 family
XcvCFBP7111P_RS13050	COG0582	viral genome integration into host DNA
XcvCFBP7111P_RS13070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcvCFBP7111P_RS13075	COG0322	excinuclease ABC activity
XcvCFBP7111P_RS13085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XcvCFBP7111P_RS13090	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XcvCFBP7111P_RS13095	COG1663	tetraacyldisaccharide 4'-kinase activity
XcvCFBP7111P_RS13100	COG1132	(ABC) transporter
XcvCFBP7111P_RS13105	COG0848	biopolymer transport protein
XcvCFBP7111P_RS13110	COG0811	peptide transport
XcvCFBP7111P_RS13125	COG1136	(ABC) transporter
XcvCFBP7111P_RS13130	COG4591	ABC-type transport system involved in lipoprotein release permease component
XcvCFBP7111P_RS13140	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XcvCFBP7111P_RS13145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XcvCFBP7111P_RS13160	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XcvCFBP7111P_RS13175	COG0354	folic acid binding
XcvCFBP7111P_RS13185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcvCFBP7111P_RS13190	COG0837	glucose binding
XcvCFBP7111P_RS13195	COG0363	glucosamine-6-phosphate deaminase activity
XcvCFBP7111P_RS13200	COG0129	dihydroxy-acid dehydratase activity
XcvCFBP7111P_RS13205	COG0800	Aldolase
XcvCFBP7111P_RS13270	COG0784	Response regulator, receiver
XcvCFBP7111P_RS13270	COG2205	protein histidine kinase activity
XcvCFBP7111P_RS13275	COG2183	response to ionizing radiation
XcvCFBP7111P_RS13300	COG3243	poly(R)-hydroxyalkanoic acid synthase
XcvCFBP7111P_RS13310	COG1183	phosphatidylcholine synthase activity
XcvCFBP7111P_RS13315	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS13330	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XcvCFBP7111P_RS13340	COG0668	transmembrane transport
XcvCFBP7111P_RS13360	COG1914	H( )-stimulated, divalent metal cation uptake system
XcvCFBP7111P_RS13390	COG0746	molybdenum cofactor guanylyltransferase activity
XcvCFBP7111P_RS13395	COG0303	'Molybdopterin
XcvCFBP7111P_RS13405	COG0708	Exodeoxyribonuclease III
XcvCFBP7111P_RS13445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XcvCFBP7111P_RS13450	COG0303	'Molybdopterin
XcvCFBP7111P_RS13455	COG1160	GTP binding
XcvCFBP7111P_RS13460	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcvCFBP7111P_RS13470	COG1426	Protein conserved in bacteria
XcvCFBP7111P_RS13480	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XcvCFBP7111P_RS13495	COG1024	Enoyl-CoA hydratase
XcvCFBP7111P_RS13495	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcvCFBP7111P_RS13500	COG0183	Belongs to the thiolase family
XcvCFBP7111P_RS13510	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XcvCFBP7111P_RS13515	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XcvCFBP7111P_RS13525	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XcvCFBP7111P_RS13535	COG1674	ftsk spoiiie
XcvCFBP7111P_RS13540	COG0492	ferredoxin-NADP+ reductase activity
XcvCFBP7111P_RS13550	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XcvCFBP7111P_RS13560	COG0542	response to heat
XcvCFBP7111P_RS13575	COG0482	sulfurtransferase activity
XcvCFBP7111P_RS13580	COG2915	High frequency lysogenization protein hflD homolog
XcvCFBP7111P_RS13610	COG5002	protein histidine kinase activity
XcvCFBP7111P_RS13630	COG0835	chemotaxis
XcvCFBP7111P_RS13630	COG0784	Response regulator, receiver
XcvCFBP7111P_RS13640	COG1558	bacterial-type flagellum-dependent cell motility
XcvCFBP7111P_RS13645	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XcvCFBP7111P_RS13655	COG4787	bacterial-type flagellum-dependent cell motility
XcvCFBP7111P_RS13665	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XcvCFBP7111P_RS13670	COG1706	bacterial-type flagellum-dependent cell motility
XcvCFBP7111P_RS13675	COG1705	Flagellar rod assembly protein muramidase FlgJ
XcvCFBP7111P_RS13675	COG3951	Flagellar rod assembly protein muramidase FlgJ
XcvCFBP7111P_RS13685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XcvCFBP7111P_RS13690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XcvCFBP7111P_RS13695	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XcvCFBP7111P_RS13725	COG2201	protein-glutamate methylesterase activity
XcvCFBP7111P_RS13745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcvCFBP7111P_RS13750	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS13755	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS13790	COG1677	Flagellar hook-basal body complex protein FliE
XcvCFBP7111P_RS13840	COG3190	flagellar
XcvCFBP7111P_RS13860	COG1684	flagellar biosynthetic protein fliR
XcvCFBP7111P_RS13920	COG0643	Histidine kinase
XcvCFBP7111P_RS13920	COG0784	Response regulator, receiver
XcvCFBP7111P_RS13920	COG2198	Histidine kinase
XcvCFBP7111P_RS13975	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS13980	COG2207	Transcriptional regulator
XcvCFBP7111P_RS14015	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XcvCFBP7111P_RS14020	COG1360	Flagellar Motor Protein
XcvCFBP7111P_RS14030	COG0835	chemotaxis
XcvCFBP7111P_RS14040	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7111P_RS14050	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS14070	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS14085	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS14090	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS14095	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS14100	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS14110	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS14115	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS14120	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS14135	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS14150	COG0835	chemotaxis
XcvCFBP7111P_RS14165	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS14175	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XcvCFBP7111P_RS14180	COG2201	protein-glutamate methylesterase activity
XcvCFBP7111P_RS14190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcvCFBP7111P_RS14220	COG0318	PFAM AMP-dependent synthetase and ligase
XcvCFBP7111P_RS14225	COG1024	Enoyl-CoA hydratase
XcvCFBP7111P_RS14230	COG2205	protein histidine kinase activity
XcvCFBP7111P_RS14230	COG2198	Histidine kinase
XcvCFBP7111P_RS14230	COG0784	Response regulator, receiver
XcvCFBP7111P_RS14245	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XcvCFBP7111P_RS14250	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XcvCFBP7111P_RS14255	COG3279	Response regulator of the LytR AlgR family
XcvCFBP7111P_RS14265	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XcvCFBP7111P_RS14275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcvCFBP7111P_RS14280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XcvCFBP7111P_RS14290	COG0505	Belongs to the CarA family
XcvCFBP7111P_RS14295	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XcvCFBP7111P_RS14300	COG2258	MOSC domain
XcvCFBP7111P_RS14305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcvCFBP7111P_RS14350	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcvCFBP7111P_RS14370	COG0277	FAD linked oxidase domain protein
XcvCFBP7111P_RS14375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XcvCFBP7111P_RS14385	COG0531	amino acid
XcvCFBP7111P_RS14390	COG0531	amino acid
XcvCFBP7111P_RS14395	COG0235	Class ii aldolase
XcvCFBP7111P_RS14400	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XcvCFBP7111P_RS14405	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XcvCFBP7111P_RS14425	COG0140	phosphoribosyl-ATP diphosphatase activity
XcvCFBP7111P_RS14425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XcvCFBP7111P_RS14430	COG0107	imidazoleglycerol-phosphate synthase activity
XcvCFBP7111P_RS14435	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XcvCFBP7111P_RS14440	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XcvCFBP7111P_RS14445	COG0131	Imidazoleglycerol-phosphate dehydratase
XcvCFBP7111P_RS14445	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XcvCFBP7111P_RS14450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcvCFBP7111P_RS14455	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XcvCFBP7111P_RS14460	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XcvCFBP7111P_RS14470	COG0124	histidyl-tRNA synthetase
XcvCFBP7111P_RS14475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcvCFBP7111P_RS14565	COG1649	PFAM Uncharacterised BCR, COG1649
XcvCFBP7111P_RS14565	COG0726	polysaccharide deacetylase
XcvCFBP7111P_RS14570	COG1215	transferase activity, transferring glycosyl groups
XcvCFBP7111P_RS14585	COG1012	belongs to the aldehyde dehydrogenase family
XcvCFBP7111P_RS14605	COG0167	dihydroorotate dehydrogenase activity
XcvCFBP7111P_RS14610	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XcvCFBP7111P_RS14615	COG0697	spore germination
XcvCFBP7111P_RS14625	COG1794	racemase activity, acting on amino acids and derivatives
XcvCFBP7111P_RS14640	COG0671	phosphoesterase, PA-phosphatase related
XcvCFBP7111P_RS14645	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XcvCFBP7111P_RS14655	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XcvCFBP7111P_RS14660	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcvCFBP7111P_RS14665	COG2203	Gaf domain
XcvCFBP7111P_RS14665	COG3706	GGDEF domain
XcvCFBP7111P_RS14665	COG4251	negative regulation of phosphorylation
XcvCFBP7111P_RS14665	COG5001	Diguanylate cyclase
XcvCFBP7111P_RS14680	COG1472	Belongs to the glycosyl hydrolase 3 family
XcvCFBP7111P_RS14710	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XcvCFBP7111P_RS14715	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XcvCFBP7111P_RS14720	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XcvCFBP7111P_RS14740	COG1469	GTP cyclohydrolase I activity
XcvCFBP7111P_RS14745	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcvCFBP7111P_RS14765	COG0477	Major facilitator Superfamily
XcvCFBP7111P_RS14770	COG2115	Belongs to the xylose isomerase family
XcvCFBP7111P_RS14775	COG1070	Carbohydrate kinase
XcvCFBP7111P_RS14785	COG1501	Belongs to the glycosyl hydrolase 31 family
XcvCFBP7111P_RS14825	COG0800	Aldolase
XcvCFBP7111P_RS14830	COG4948	Mandelate Racemase Muconate Lactonizing
XcvCFBP7111P_RS14840	COG3734	2-keto-3-deoxy-galactonokinase
XcvCFBP7111P_RS14845	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XcvCFBP7111P_RS14855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcvCFBP7111P_RS14870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XcvCFBP7111P_RS14875	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XcvCFBP7111P_RS14890	COG0351	phosphomethylpyrimidine kinase
XcvCFBP7111P_RS14915	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS14920	COG1741	Belongs to the pirin family
XcvCFBP7111P_RS14935	COG0582	viral genome integration into host DNA
XcvCFBP7111P_RS15105	COG3179	chitinase
XcvCFBP7111P_RS15150	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
XcvCFBP7111P_RS15270	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XcvCFBP7111P_RS15275	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XcvCFBP7111P_RS15280	COG2137	regulation of response to DNA damage stimulus
XcvCFBP7111P_RS15290	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XcvCFBP7111P_RS15295	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcvCFBP7111P_RS15305	COG1546	Belongs to the CinA family
XcvCFBP7111P_RS15310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XcvCFBP7111P_RS15320	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XcvCFBP7111P_RS15325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XcvCFBP7111P_RS15335	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XcvCFBP7111P_RS15340	COG1534	Rna-binding protein
XcvCFBP7111P_RS15355	COG1238	metal cluster binding
XcvCFBP7111P_RS15360	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcvCFBP7111P_RS15365	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XcvCFBP7111P_RS15370	COG2840	Smr protein MutS2
XcvCFBP7111P_RS15375	COG0585	pseudouridine synthase activity
XcvCFBP7111P_RS15380	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XcvCFBP7111P_RS15385	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XcvCFBP7111P_RS15390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XcvCFBP7111P_RS15395	COG0148	phosphopyruvate hydratase activity
XcvCFBP7111P_RS15410	COG0504	CTP synthase activity
XcvCFBP7111P_RS15435	COG0306	phosphate transporter
XcvCFBP7111P_RS15450	COG1253	flavin adenine dinucleotide binding
XcvCFBP7111P_RS15465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcvCFBP7111P_RS15470	COG0477	Major facilitator Superfamily
XcvCFBP7111P_RS15480	COG1136	(ABC) transporter
XcvCFBP7111P_RS15505	COG2264	protein methyltransferase activity
XcvCFBP7111P_RS15535	COG2244	polysaccharide biosynthetic process
XcvCFBP7111P_RS15590	COG1595	DNA-templated transcription, initiation
XcvCFBP7111P_RS15605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcvCFBP7111P_RS15615	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcvCFBP7111P_RS15625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcvCFBP7111P_RS15640	COG4191	Histidine kinase
XcvCFBP7111P_RS15640	COG0784	Response regulator, receiver
XcvCFBP7111P_RS15645	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XcvCFBP7111P_RS15675	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS15775	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS15780	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcvCFBP7111P_RS15785	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XcvCFBP7111P_RS15805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XcvCFBP7111P_RS15810	COG0077	Prephenate dehydratase
XcvCFBP7111P_RS15810	COG1605	Chorismate mutase
XcvCFBP7111P_RS15815	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XcvCFBP7111P_RS15820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XcvCFBP7111P_RS15870	COG1228	amidohydrolase
XcvCFBP7111P_RS15875	COG2986	histidine ammonia-lyase
XcvCFBP7111P_RS15885	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XcvCFBP7111P_RS15895	COG4993	Dehydrogenase
XcvCFBP7111P_RS15905	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XcvCFBP7111P_RS15920	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XcvCFBP7111P_RS15925	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XcvCFBP7111P_RS15930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcvCFBP7111P_RS15940	COG3115	cell septum assembly
XcvCFBP7111P_RS15955	COG0359	binds to the 23S rRNA
XcvCFBP7111P_RS15960	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XcvCFBP7111P_RS15965	COG0360	Binds together with S18 to 16S ribosomal RNA
XcvCFBP7111P_RS15970	COG0316	Belongs to the HesB IscA family
XcvCFBP7111P_RS15980	COG0017	Asparaginyl-tRNA synthetase
XcvCFBP7111P_RS16065	COG0288	reversible hydration of carbon dioxide
XcvCFBP7111P_RS16070	COG0662	Cupin 2, conserved barrel domain protein
XcvCFBP7111P_RS16080	COG3844	kynureninase activity
XcvCFBP7111P_RS16085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcvCFBP7111P_RS16090	COG2925	Exonuclease
XcvCFBP7111P_RS16110	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XcvCFBP7111P_RS16115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcvCFBP7111P_RS16115	COG0116	Belongs to the methyltransferase superfamily
XcvCFBP7111P_RS16125	COG0488	(ABC) transporter
XcvCFBP7111P_RS16160	COG0494	nUDIX hydrolase
XcvCFBP7111P_RS16170	COG1024	Enoyl-CoA hydratase
XcvCFBP7111P_RS16180	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XcvCFBP7111P_RS16185	COG0659	secondary active sulfate transmembrane transporter activity
XcvCFBP7111P_RS16210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XcvCFBP7111P_RS16215	COG0573	inorganic phosphate transmembrane transporter activity
XcvCFBP7111P_RS16220	COG0581	inorganic phosphate transmembrane transporter activity
XcvCFBP7111P_RS16225	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XcvCFBP7111P_RS16230	COG0704	Plays a role in the regulation of phosphate uptake
XcvCFBP7111P_RS16240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcvCFBP7111P_RS16250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcvCFBP7111P_RS16260	COG0557	exoribonuclease II activity
XcvCFBP7111P_RS16295	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7111P_RS16300	COG2226	methyltransferase
XcvCFBP7111P_RS16305	COG1410	methionine synthase
XcvCFBP7111P_RS16305	COG0646	methionine synthase
XcvCFBP7111P_RS16310	COG0646	methionine synthase
XcvCFBP7111P_RS16310	COG1410	methionine synthase
XcvCFBP7111P_RS16320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcvCFBP7111P_RS16345	COG2900	Belongs to the SlyX family
XcvCFBP7111P_RS16360	COG0386	Belongs to the glutathione peroxidase family
XcvCFBP7111P_RS16370	COG1725	Transcriptional regulator
XcvCFBP7111P_RS16375	COG1131	(ABC) transporter
XcvCFBP7111P_RS16410	COG1253	flavin adenine dinucleotide binding
XcvCFBP7111P_RS16435	COG2850	peptidyl-arginine hydroxylation
XcvCFBP7111P_RS16445	COG0567	Dehydrogenase, E1 component
XcvCFBP7111P_RS16470	COG1132	(ABC) transporter
XcvCFBP7111P_RS16475	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS16505	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XcvCFBP7111P_RS16515	COG0484	heat shock protein binding
XcvCFBP7111P_RS16520	COG0443	Heat shock 70 kDa protein
XcvCFBP7111P_RS16525	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XcvCFBP7111P_RS16530	COG1420	regulation of RNA biosynthetic process
XcvCFBP7111P_RS16535	COG0497	DNA recombination
XcvCFBP7111P_RS16545	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcvCFBP7111P_RS16560	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XcvCFBP7111P_RS16585	COG3706	GGDEF domain
XcvCFBP7111P_RS16630	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS16640	COG0415	Belongs to the DNA photolyase family
XcvCFBP7111P_RS16645	COG0305	Participates in initiation and elongation during chromosome replication
XcvCFBP7111P_RS16655	COG0367	asparagine synthase
XcvCFBP7111P_RS16675	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7111P_RS16690	COG0084	hydrolase, TatD family'
XcvCFBP7111P_RS16695	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XcvCFBP7111P_RS16750	COG0386	Belongs to the glutathione peroxidase family
XcvCFBP7111P_RS16760	COG0339	signal peptide processing
XcvCFBP7111P_RS16810	COG2814	Major facilitator Superfamily
XcvCFBP7111P_RS16815	COG1566	PFAM secretion protein HlyD family protein
XcvCFBP7111P_RS16840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XcvCFBP7111P_RS16855	COG4774	siderophore transport
XcvCFBP7111P_RS16865	COG0367	asparagine synthase
XcvCFBP7111P_RS16870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcvCFBP7111P_RS16875	COG1393	Belongs to the ArsC family
XcvCFBP7111P_RS16885	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XcvCFBP7111P_RS16925	COG0052	Belongs to the universal ribosomal protein uS2 family
XcvCFBP7111P_RS16930	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XcvCFBP7111P_RS16940	COG0528	UMP kinase activity
XcvCFBP7111P_RS16945	COG0233	cytoplasmic translational termination
XcvCFBP7111P_RS16950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XcvCFBP7111P_RS16955	COG0575	Belongs to the CDS family
XcvCFBP7111P_RS16960	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XcvCFBP7111P_RS16965	COG0750	zinc metalloprotease
XcvCFBP7111P_RS16980	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcvCFBP7111P_RS16985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcvCFBP7111P_RS16990	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcvCFBP7111P_RS16995	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcvCFBP7111P_RS17010	COG0825	malonyl-CoA metabolic process
XcvCFBP7111P_RS17025	COG1981	membrane
XcvCFBP7111P_RS17045	COG1695	Transcriptional regulator
XcvCFBP7111P_RS17070	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XcvCFBP7111P_RS17080	COG2040	homocysteine
XcvCFBP7111P_RS17085	COG0833	amino acid
XcvCFBP7111P_RS17090	COG0346	lactoylglutathione lyase activity
XcvCFBP7111P_RS17095	COG1131	(ABC) transporter
XcvCFBP7111P_RS17110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcvCFBP7111P_RS17110	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcvCFBP7111P_RS17120	COG2878	Part of a membrane complex involved in electron transport
XcvCFBP7111P_RS17145	COG1595	DNA-templated transcription, initiation
XcvCFBP7111P_RS17170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcvCFBP7111P_RS17185	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcvCFBP7111P_RS17190	COG0251	oxidation-reduction process
XcvCFBP7111P_RS17200	COG0392	lysyltransferase activity
XcvCFBP7111P_RS17200	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XcvCFBP7111P_RS17235	COG2814	Major facilitator Superfamily
XcvCFBP7111P_RS17240	COG1902	pentaerythritol trinitrate reductase activity
XcvCFBP7111P_RS17250	COG2824	Alkylphosphonate utilization operon protein PhnA
XcvCFBP7111P_RS17260	COG1047	Peptidyl-prolyl cis-trans
XcvCFBP7111P_RS17265	COG1077	Cell shape determining protein MreB Mrl
XcvCFBP7111P_RS17280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XcvCFBP7111P_RS17290	COG5487	UPF0391 membrane protein
XcvCFBP7111P_RS17295	COG1451	nucleotide metabolic process
XcvCFBP7111P_RS17320	COG0183	Belongs to the thiolase family
XcvCFBP7111P_RS17350	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcvCFBP7111P_RS17350	COG1793	dna ligase
XcvCFBP7111P_RS17360	COG1793	dna ligase
XcvCFBP7111P_RS17365	COG1201	RNA secondary structure unwinding
XcvCFBP7111P_RS17375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcvCFBP7111P_RS17380	COG1278	Cold shock
XcvCFBP7111P_RS17385	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XcvCFBP7111P_RS17390	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XcvCFBP7111P_RS17395	COG1472	Belongs to the glycosyl hydrolase 3 family
XcvCFBP7111P_RS17400	COG3046	protein related to deoxyribodipyrimidine photolyase
XcvCFBP7111P_RS17410	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XcvCFBP7111P_RS17415	COG2954	triphosphatase activity
XcvCFBP7111P_RS17420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XcvCFBP7111P_RS17430	COG1381	Involved in DNA repair and RecF pathway recombination
XcvCFBP7111P_RS17435	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XcvCFBP7111P_RS17440	COG0571	ribonuclease III activity
XcvCFBP7111P_RS17455	COG0481	GTPase activity
XcvCFBP7111P_RS17460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcvCFBP7111P_RS17475	COG1024	Enoyl-CoA hydratase
XcvCFBP7111P_RS17475	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcvCFBP7111P_RS17485	COG2801	Transposase and inactivated derivatives
XcvCFBP7111P_RS17515	COG1024	Enoyl-CoA hydratase
XcvCFBP7111P_RS17520	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7111P_RS17540	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XcvCFBP7111P_RS17545	COG3250	beta-galactosidase activity
XcvCFBP7111P_RS17565	COG2963	transposase activity
XcvCFBP7111P_RS17570	COG3209	COG3209 Rhs family protein
XcvCFBP7111P_RS17650	COG2003	Belongs to the UPF0758 family
XcvCFBP7111P_RS17670	COG2003	Belongs to the UPF0758 family
XcvCFBP7111P_RS17725	COG3209	COG3209 Rhs family protein
XcvCFBP7111P_RS17755	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XcvCFBP7111P_RS17765	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XcvCFBP7111P_RS17790	COG0534	Mate efflux family protein
XcvCFBP7111P_RS17795	COG0335	large ribosomal subunit rRNA binding
XcvCFBP7111P_RS17800	COG0336	Belongs to the RNA methyltransferase TrmD family
XcvCFBP7111P_RS17805	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XcvCFBP7111P_RS17810	COG0228	four-way junction DNA binding
XcvCFBP7111P_RS17815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcvCFBP7111P_RS17825	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XcvCFBP7111P_RS17835	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcvCFBP7111P_RS17865	COG0784	Response regulator, receiver
XcvCFBP7111P_RS17865	COG4191	Histidine kinase
XcvCFBP7111P_RS17870	COG4999	Histidine kinase
XcvCFBP7111P_RS17870	COG3437	response regulator, receiver
XcvCFBP7111P_RS17870	COG2205	protein histidine kinase activity
XcvCFBP7111P_RS17870	COG3850	Histidine kinase
XcvCFBP7111P_RS17875	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcvCFBP7111P_RS17885	COG2205	protein histidine kinase activity
XcvCFBP7111P_RS17890	COG5507	3-demethylubiquinone-9 3-methyltransferase
XcvCFBP7111P_RS17900	COG4771	TonB-dependent receptor
XcvCFBP7111P_RS17925	COG2172	sigma factor antagonist activity
XcvCFBP7111P_RS17930	COG1366	Belongs to the anti-sigma-factor antagonist family
XcvCFBP7111P_RS17935	COG1366	Belongs to the anti-sigma-factor antagonist family
XcvCFBP7111P_RS17945	COG0326	Molecular chaperone. Has ATPase activity
XcvCFBP7111P_RS17950	COG2207	Transcriptional regulator
XcvCFBP7111P_RS17960	COG3152	Membrane
XcvCFBP7111P_RS17975	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XcvCFBP7111P_RS17980	COG1845	cytochrome c oxidase, subunit III
XcvCFBP7111P_RS17985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XcvCFBP7111P_RS18000	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XcvCFBP7111P_RS18005	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XcvCFBP7111P_RS18010	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XcvCFBP7111P_RS18015	COG0196	riboflavin kinase activity
XcvCFBP7111P_RS18025	COG0268	Binds directly to 16S ribosomal RNA
XcvCFBP7111P_RS18030	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XcvCFBP7111P_RS18035	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XcvCFBP7111P_RS18040	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XcvCFBP7111P_RS18045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XcvCFBP7111P_RS18050	COG0824	Thioesterase
XcvCFBP7111P_RS18065	COG1946	Acyl-CoA thioesterase
XcvCFBP7111P_RS18085	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XcvCFBP7111P_RS18095	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XcvCFBP7111P_RS18120	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XcvCFBP7111P_RS18135	COG2197	response regulator
XcvCFBP7111P_RS18140	COG4585	Histidine kinase
XcvCFBP7111P_RS18155	COG0850	regulation of cytokinetic process
XcvCFBP7111P_RS18160	COG2894	cell division
XcvCFBP7111P_RS18165	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XcvCFBP7111P_RS18175	COG0642	Histidine kinase
XcvCFBP7111P_RS18180	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7111P_RS18195	COG2194	sulfuric ester hydrolase activity
XcvCFBP7111P_RS18210	COG2814	Major facilitator Superfamily
XcvCFBP7111P_RS18215	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcvCFBP7111P_RS18215	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcvCFBP7111P_RS18225	COG0656	L-ascorbic acid biosynthetic process
XcvCFBP7111P_RS18230	COG0753	catalase activity
XcvCFBP7111P_RS18255	COG2207	Transcriptional regulator
XcvCFBP7111P_RS18255	COG1917	Cupin 2, conserved barrel domain protein
XcvCFBP7111P_RS18270	COG0823	Involved in the tonB-independent uptake of proteins
XcvCFBP7111P_RS18270	COG1506	peptidase
XcvCFBP7111P_RS18285	COG1297	OPT oligopeptide transporter protein
XcvCFBP7111P_RS18300	COG0587	DNA-directed DNA polymerase activity
XcvCFBP7111P_RS18320	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcvCFBP7111P_RS18355	COG2080	2 iron, 2 sulfur cluster binding
XcvCFBP7111P_RS18360	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcvCFBP7111P_RS18365	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcvCFBP7111P_RS18395	COG0492	ferredoxin-NADP+ reductase activity
XcvCFBP7111P_RS18410	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS18415	COG3537	Alpha-1,2-mannosidase
XcvCFBP7111P_RS18425	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS18430	COG3387	PFAM Glycoside hydrolase 15-related
XcvCFBP7111P_RS18440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcvCFBP7111P_RS18505	COG1309	transcriptional regulator
XcvCFBP7111P_RS18510	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS18520	COG0308	aminopeptidase N
XcvCFBP7111P_RS18525	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XcvCFBP7111P_RS18535	COG0330	HflC and HflK could
XcvCFBP7111P_RS18540	COG0330	HflC and HflK could
XcvCFBP7111P_RS18560	COG0678	peroxiredoxin activity
XcvCFBP7111P_RS18570	COG4953	penicillin-binding protein 1C
XcvCFBP7111P_RS18590	COG2373	Large extracellular alpha-helical protein
XcvCFBP7111P_RS18635	COG3829	transcription factor binding
XcvCFBP7111P_RS18660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XcvCFBP7111P_RS18665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XcvCFBP7111P_RS18685	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcvCFBP7111P_RS18695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcvCFBP7111P_RS18705	COG1399	metal-binding, possibly nucleic acid-binding protein
XcvCFBP7111P_RS18710	COG0424	maF-like protein
XcvCFBP7111P_RS18735	COG0714	Associated with various cellular activities
XcvCFBP7111P_RS18755	COG0537	adenosine 5'-monophosphoramidase activity
XcvCFBP7111P_RS18760	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XcvCFBP7111P_RS18765	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XcvCFBP7111P_RS18805	COG1129	ABC transporter
XcvCFBP7111P_RS18875	COG0314	molybdopterin synthase activity
XcvCFBP7111P_RS18880	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XcvCFBP7111P_RS18885	COG0315	cyclic pyranopterin monophosphate synthase activity
XcvCFBP7111P_RS18895	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XcvCFBP7111P_RS18900	COG1234	tRNA 3'-trailer cleavage
XcvCFBP7111P_RS18905	COG3642	lipopolysaccharide core region biosynthetic process
XcvCFBP7111P_RS18910	COG0859	PFAM glycosyl transferase family 9
XcvCFBP7111P_RS18930	COG0631	protein serine/threonine phosphatase activity
XcvCFBP7111P_RS18935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcvCFBP7111P_RS18940	COG0328	RNA-DNA hybrid ribonuclease activity
XcvCFBP7111P_RS18950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcvCFBP7111P_RS18960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcvCFBP7111P_RS18990	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XcvCFBP7111P_RS19000	COG0544	peptidyl-prolyl cis-trans isomerase activity
XcvCFBP7111P_RS19010	COG3852	Histidine kinase
XcvCFBP7111P_RS19030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XcvCFBP7111P_RS19075	COG4695	Portal protein
XcvCFBP7111P_RS19120	COG3179	chitinase
XcvCFBP7111P_RS19325	COG0473	3-isopropylmalate dehydrogenase activity
XcvCFBP7111P_RS19340	COG4783	chaperone-mediated protein folding
XcvCFBP7111P_RS19355	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XcvCFBP7111P_RS19365	COG0438	transferase activity, transferring glycosyl groups
XcvCFBP7111P_RS19370	COG0671	phosphoesterase, PA-phosphatase related
XcvCFBP7111P_RS19375	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcvCFBP7111P_RS19385	COG3291	Pkd domain containing protein
XcvCFBP7111P_RS19390	COG2833	Protein of unknown function (DUF455)
XcvCFBP7111P_RS19410	COG0285	dihydrofolate synthase activity
XcvCFBP7111P_RS19415	COG0406	alpha-ribazole phosphatase activity
XcvCFBP7111P_RS19455	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XcvCFBP7111P_RS19460	COG4208	sulfate ABC transporter
XcvCFBP7111P_RS19465	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XcvCFBP7111P_RS19470	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XcvCFBP7111P_RS19475	COG0156	8-amino-7-oxononanoate synthase activity
XcvCFBP7111P_RS19505	COG0604	alcohol dehydrogenase
XcvCFBP7111P_RS19510	COG0446	pyridine nucleotide-disulphide oxidoreductase
XcvCFBP7111P_RS19510	COG1902	pentaerythritol trinitrate reductase activity
XcvCFBP7111P_RS19525	COG0625	glutathione transferase activity
XcvCFBP7111P_RS19530	COG0039	L-malate dehydrogenase activity
XcvCFBP7111P_RS19535	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XcvCFBP7111P_RS19540	COG1217	gtp-binding protein TYPA
XcvCFBP7111P_RS19550	COG0154	amidase activity
XcvCFBP7111P_RS19565	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XcvCFBP7111P_RS19585	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XcvCFBP7111P_RS19590	COG0203	ribosomal protein L17
XcvCFBP7111P_RS19615	COG0201	protein transport
XcvCFBP7111P_RS19620	COG0200	Binds to the 23S rRNA
XcvCFBP7111P_RS19625	COG1841	ribosomal large subunit assembly
XcvCFBP7111P_RS19635	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XcvCFBP7111P_RS19640	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XcvCFBP7111P_RS19645	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XcvCFBP7111P_RS19655	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XcvCFBP7111P_RS19660	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XcvCFBP7111P_RS19670	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XcvCFBP7111P_RS19675	COG0255	Belongs to the universal ribosomal protein uL29 family
XcvCFBP7111P_RS19680	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XcvCFBP7111P_RS19685	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XcvCFBP7111P_RS19695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XcvCFBP7111P_RS19700	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XcvCFBP7111P_RS19710	COG0088	Forms part of the polypeptide exit tunnel
XcvCFBP7111P_RS19715	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XcvCFBP7111P_RS19720	COG0051	transcription antitermination factor activity, RNA binding
XcvCFBP7111P_RS19725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcvCFBP7111P_RS19730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XcvCFBP7111P_RS19735	COG0049	tRNA binding
XcvCFBP7111P_RS19740	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XcvCFBP7111P_RS19745	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XcvCFBP7111P_RS19750	COG0085	RNA polymerase activity
XcvCFBP7111P_RS19755	COG0222	ribosome binding
XcvCFBP7111P_RS19760	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XcvCFBP7111P_RS19765	COG0081	regulation of translation
XcvCFBP7111P_RS19770	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XcvCFBP7111P_RS19775	COG0250	Participates in transcription elongation, termination and antitermination
XcvCFBP7111P_RS19790	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcvCFBP7111P_RS19810	COG0012	GTP binding
XcvCFBP7111P_RS19815	COG0193	aminoacyl-tRNA hydrolase activity
XcvCFBP7111P_RS19820	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XcvCFBP7111P_RS19825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XcvCFBP7111P_RS19835	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XcvCFBP7111P_RS19840	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XcvCFBP7111P_RS19850	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XcvCFBP7111P_RS19855	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XcvCFBP7111P_RS19865	COG0521	Mo-molybdopterin cofactor biosynthetic process
XcvCFBP7111P_RS19880	COG1254	Belongs to the acylphosphatase family
XcvCFBP7111P_RS19885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcvCFBP7111P_RS19890	COG1295	ribonuclease BN
XcvCFBP7111P_RS19915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XcvCFBP7111P_RS19920	COG1404	Belongs to the peptidase S8 family
XcvCFBP7111P_RS19930	COG1404	Belongs to the peptidase S8 family
XcvCFBP7111P_RS19935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcvCFBP7111P_RS19960	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XcvCFBP7111P_RS19980	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XcvCFBP7111P_RS20015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcvCFBP7111P_RS20015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcvCFBP7111P_RS20035	COG2890	protein-(glutamine-N5) methyltransferase activity
XcvCFBP7111P_RS20045	COG3634	alkyl hydroperoxide reductase activity
XcvCFBP7111P_RS20050	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS20060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcvCFBP7111P_RS20065	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XcvCFBP7111P_RS20075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XcvCFBP7111P_RS20085	COG2197	response regulator
XcvCFBP7111P_RS20110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcvCFBP7111P_RS20120	COG0697	spore germination
XcvCFBP7111P_RS20145	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XcvCFBP7111P_RS20175	COG1024	Enoyl-CoA hydratase
XcvCFBP7111P_RS20190	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS20195	COG3384	dioxygenase
XcvCFBP7111P_RS20225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcvCFBP7111P_RS20230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcvCFBP7111P_RS20245	COG2096	Adenosyltransferase
XcvCFBP7111P_RS20250	COG0123	including yeast histone deacetylase and acetoin utilization protein
XcvCFBP7111P_RS20255	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XcvCFBP7111P_RS20260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcvCFBP7111P_RS20265	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XcvCFBP7111P_RS20270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XcvCFBP7111P_RS20275	COG2967	ApaG domain
XcvCFBP7111P_RS20280	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XcvCFBP7111P_RS20290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XcvCFBP7111P_RS20300	COG0747	negative chemotaxis
XcvCFBP7111P_RS20320	COG0431	NADPH-dependent FMN reductase
XcvCFBP7111P_RS20325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcvCFBP7111P_RS20335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcvCFBP7111P_RS20340	COG1116	anion transmembrane transporter activity
XcvCFBP7111P_RS20350	COG3829	transcription factor binding
XcvCFBP7111P_RS20365	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XcvCFBP7111P_RS20370	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XcvCFBP7111P_RS20390	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XcvCFBP7111P_RS20400	COG0642	Histidine kinase
XcvCFBP7111P_RS20415	COG4181	ATPase activity
XcvCFBP7111P_RS20425	COG2175	clavaminate synthase activity
XcvCFBP7111P_RS20435	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XcvCFBP7111P_RS20440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcvCFBP7111P_RS20460	COG4771	TonB-dependent receptor
XcvCFBP7111P_RS20470	COG0667	Aldo Keto reductase
XcvCFBP7111P_RS20480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XcvCFBP7111P_RS20485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcvCFBP7111P_RS20495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcvCFBP7111P_RS20500	COG4106	trans-aconitate 2-methyltransferase activity
XcvCFBP7111P_RS20510	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XcvCFBP7111P_RS20550	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XcvCFBP7111P_RS20560	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XcvCFBP7111P_RS20565	COG2226	methyltransferase
XcvCFBP7111P_RS20600	COG0366	Alpha amylase catalytic
XcvCFBP7111P_RS20625	COG3321	synthase
XcvCFBP7111P_RS20625	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS20625	COG0604	alcohol dehydrogenase
XcvCFBP7111P_RS20640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XcvCFBP7111P_RS20650	COG0494	nUDIX hydrolase
XcvCFBP7111P_RS20655	COG0653	protein targeting
XcvCFBP7111P_RS20660	COG0739	heme binding
XcvCFBP7111P_RS20670	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XcvCFBP7111P_RS20685	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XcvCFBP7111P_RS20690	COG1181	Belongs to the D-alanine--D-alanine ligase family
XcvCFBP7111P_RS20695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcvCFBP7111P_RS20700	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XcvCFBP7111P_RS20710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcvCFBP7111P_RS20715	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XcvCFBP7111P_RS20720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XcvCFBP7111P_RS20735	COG3116	cell division
XcvCFBP7111P_RS20740	COG0275	rRNA processing
XcvCFBP7111P_RS20775	COG0792	nuclease activity
XcvCFBP7111P_RS20780	COG1988	membrane-bound metal-dependent
XcvCFBP7111P_RS20785	COG0277	FAD linked oxidase domain protein
XcvCFBP7111P_RS20790	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7111P_RS20795	COG2205	protein histidine kinase activity
XcvCFBP7111P_RS20800	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XcvCFBP7111P_RS20805	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XcvCFBP7111P_RS20810	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XcvCFBP7111P_RS20840	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XcvCFBP7111P_RS20845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcvCFBP7111P_RS20850	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XcvCFBP7111P_RS20870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcvCFBP7111P_RS20870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcvCFBP7111P_RS20880	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XcvCFBP7111P_RS20885	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XcvCFBP7111P_RS20895	COG0488	(ABC) transporter
XcvCFBP7111P_RS20905	COG0697	spore germination
XcvCFBP7111P_RS20915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcvCFBP7111P_RS20930	COG3791	Glutathione-dependent formaldehyde-activating
XcvCFBP7111P_RS20960	COG2205	protein histidine kinase activity
XcvCFBP7111P_RS20980	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcvCFBP7111P_RS20990	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XcvCFBP7111P_RS21005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcvCFBP7111P_RS21020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XcvCFBP7111P_RS21025	COG1012	belongs to the aldehyde dehydrogenase family
XcvCFBP7111P_RS21030	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcvCFBP7111P_RS21035	COG0617	tRNA 3'-terminal CCA addition
XcvCFBP7111P_RS21050	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XcvCFBP7111P_RS21055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcvCFBP7111P_RS21060	COG1609	Transcriptional regulator
XcvCFBP7111P_RS21070	COG2188	Transcriptional regulator
XcvCFBP7111P_RS21085	COG3250	beta-galactosidase activity
XcvCFBP7111P_RS21130	COG2165	general secretion pathway protein
XcvCFBP7111P_RS21135	COG1459	type II secretion system
XcvCFBP7111P_RS21190	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XcvCFBP7111P_RS21195	COG4191	Histidine kinase
XcvCFBP7111P_RS21200	COG0784	Response regulator, receiver
XcvCFBP7111P_RS21205	COG4251	negative regulation of phosphorylation
XcvCFBP7111P_RS21210	COG2823	Periplasmic or secreted lipoprotein
XcvCFBP7111P_RS21215	COG0673	inositol 2-dehydrogenase activity
XcvCFBP7111P_RS21220	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XcvCFBP7111P_RS21255	COG1051	belongs to the nudix hydrolase family
XcvCFBP7111P_RS21255	COG1056	cytidyltransferase-related domain
XcvCFBP7111P_RS21265	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS21280	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XcvCFBP7111P_RS21285	COG0321	lipoyl(octanoyl) transferase activity
XcvCFBP7111P_RS21290	COG2921	Belongs to the UPF0250 family
XcvCFBP7111P_RS21305	COG1686	Belongs to the peptidase S11 family
XcvCFBP7111P_RS21315	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XcvCFBP7111P_RS21320	COG2951	lytic endotransglycosylase activity
XcvCFBP7111P_RS21330	COG0772	Belongs to the SEDS family
XcvCFBP7111P_RS21345	COG1792	Involved in formation and maintenance of cell shape
XcvCFBP7111P_RS21350	COG1077	Cell shape determining protein MreB Mrl
XcvCFBP7111P_RS21355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcvCFBP7111P_RS21360	COG3284	Transcriptional regulator
XcvCFBP7111P_RS21410	COG0308	aminopeptidase N
XcvCFBP7111P_RS21415	COG3300	MHYT domain
XcvCFBP7111P_RS21415	COG5001	Diguanylate cyclase
XcvCFBP7111P_RS21420	COG2226	methyltransferase
XcvCFBP7111P_RS21445	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XcvCFBP7111P_RS21450	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XcvCFBP7111P_RS21455	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XcvCFBP7111P_RS21465	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XcvCFBP7111P_RS21475	COG2832	Protein of unknown function (DUF454)
XcvCFBP7111P_RS21485	COG0436	Aminotransferase
XcvCFBP7111P_RS21490	COG1505	serine-type exopeptidase activity
XcvCFBP7111P_RS21520	COG0181	hydroxymethylbilane synthase activity
XcvCFBP7111P_RS21530	COG3275	phosphorelay sensor kinase activity
XcvCFBP7111P_RS21540	COG2943	transferase activity, transferring hexosyl groups
XcvCFBP7111P_RS21570	COG0659	secondary active sulfate transmembrane transporter activity
XcvCFBP7111P_RS21575	COG5297	Belongs to the glycosyl hydrolase family 6
XcvCFBP7111P_RS21575	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcvCFBP7111P_RS21580	COG0840	transmembrane signaling receptor activity
XcvCFBP7111P_RS21630	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
XcvCFBP7111P_RS21650	COG1113	amino acid transport
XcvCFBP7111P_RS21665	COG0697	spore germination
XcvCFBP7111P_RS21705	COG0823	Involved in the tonB-independent uptake of proteins
XcvCFBP7111P_RS21705	COG1506	peptidase
XcvCFBP7111P_RS21740	COG0435	Glutathione S-transferase
XcvCFBP7111P_RS21750	COG4221	oxidoreductase activity
XcvCFBP7111P_RS21765	COG4221	oxidoreductase activity
XcvCFBP7111P_RS21790	COG1082	Xylose isomerase domain protein TIM barrel
XcvCFBP7111P_RS21855	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
XcvCFBP7111P_RS21910	COG1802	Transcriptional regulator
XcvCFBP7111P_RS21920	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcvCFBP7111P_RS21945	COG3052	prosthetic group binding
XcvCFBP7111P_RS21975	COG2353	YceI-like domain
XcvCFBP7111P_RS21980	COG0778	Nitroreductase
XcvCFBP7111P_RS22010	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XcvCFBP7111P_RS22015	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XcvCFBP7111P_RS22025	COG3386	PFAM SMP-30 Gluconolaconase
XcvCFBP7111P_RS22040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XcvCFBP7111P_RS22055	COG0459	protein refolding
XcvCFBP7111P_RS22065	COG2356	endonuclease I
XcvCFBP7111P_RS22075	COG1324	tolerance protein
XcvCFBP7111P_RS22085	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XcvCFBP7111P_RS22090	COG0511	ligase activity, forming carbon-carbon bonds
XcvCFBP7111P_RS22100	COG0439	Biotin carboxylase
XcvCFBP7111P_RS22120	COG2264	protein methyltransferase activity
XcvCFBP7111P_RS22145	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XcvCFBP7111P_RS22150	COG4589	Belongs to the CDS family
XcvCFBP7111P_RS22175	COG0671	phosphoesterase, PA-phosphatase related
XcvCFBP7111P_RS22175	COG2453	phosphatase
XcvCFBP7111P_RS22180	COG2267	carboxylic ester hydrolase activity
XcvCFBP7111P_RS22185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcvCFBP7111P_RS22190	COG0138	bifunctional purine biosynthesis protein purh
XcvCFBP7111P_RS22200	COG0151	Belongs to the GarS family
XcvCFBP7111P_RS22205	COG1289	transmembrane transporter activity
XcvCFBP7111P_RS22210	COG2814	Major facilitator Superfamily
XcvCFBP7111P_RS22220	COG2814	Major facilitator Superfamily
XcvCFBP7111P_RS22235	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcvCFBP7111P_RS22255	COG0316	Belongs to the HesB IscA family
XcvCFBP7111P_RS22295	COG1051	belongs to the nudix hydrolase family
XcvCFBP7111P_RS22310	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XcvCFBP7111P_RS22320	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XcvCFBP7111P_RS22330	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XcvCFBP7111P_RS22335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcvCFBP7111P_RS22345	COG0134	indole-3-glycerol-phosphate synthase activity
XcvCFBP7111P_RS22350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XcvCFBP7111P_RS22375	COG1597	lipid kinase activity
XcvCFBP7111P_RS22380	COG0456	acetyltransferase
XcvCFBP7111P_RS22395	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XcvCFBP7111P_RS22400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XcvCFBP7111P_RS22430	COG2111	Na H antiporter
XcvCFBP7111P_RS22430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcvCFBP7111P_RS22435	COG1006	Multisubunit Na H antiporter MnhC subunit
XcvCFBP7111P_RS22440	COG0651	ATP synthesis coupled electron transport
XcvCFBP7111P_RS22450	COG2212	antiporter activity
XcvCFBP7111P_RS22455	COG1320	monovalent cation:proton antiporter activity
XcvCFBP7111P_RS22475	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XcvCFBP7111P_RS22495	COG3104	oligopeptide transport
XcvCFBP7111P_RS22500	COG3483	tryptophan 2,3-dioxygenase activity
XcvCFBP7111P_RS22510	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XcvCFBP7111P_RS22525	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcvCFBP7111P_RS22530	COG0513	Belongs to the DEAD box helicase family
XcvCFBP7111P_RS22540	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS22545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7111P_RS22580	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS22585	COG0702	epimerase
XcvCFBP7111P_RS22610	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcvCFBP7111P_RS22615	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcvCFBP7111P_RS22620	COG0297	glycogen (starch) synthase activity
XcvCFBP7111P_RS22630	COG2354	Protein conserved in bacteria
XcvCFBP7111P_RS22635	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcvCFBP7111P_RS22640	COG1368	sulfuric ester hydrolase activity
XcvCFBP7111P_RS22645	COG1511	domain protein
XcvCFBP7111P_RS22645	COG3264	Mechanosensitive ion channel
XcvCFBP7111P_RS22715	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XcvCFBP7111P_RS22805	COG1733	regulation of RNA biosynthetic process
XcvCFBP7111P_RS22855	COG1902	pentaerythritol trinitrate reductase activity
XcvCFBP7111P_RS22875	COG2315	Protein conserved in bacteria
XcvCFBP7111P_RS22915	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XcvCFBP7111P_RS22920	COG1040	competence protein
XcvCFBP7111P_RS22925	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XcvCFBP7111P_RS22930	COG0156	8-amino-7-oxononanoate synthase activity
XcvCFBP7111P_RS22940	COG2267	carboxylic ester hydrolase activity
XcvCFBP7111P_RS22945	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS22970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XcvCFBP7111P_RS22980	COG0445	tRNA wobble uridine modification
XcvCFBP7111P_RS22995	COG0657	acetylesterase activity
XcvCFBP7111P_RS23010	COG1414	Transcriptional regulator
XcvCFBP7111P_RS23020	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XcvCFBP7111P_RS23025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcvCFBP7111P_RS23035	COG3485	protocatechuate 3,4-dioxygenase
XcvCFBP7111P_RS23040	COG3485	protocatechuate 3,4-dioxygenase
XcvCFBP7111P_RS23050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XcvCFBP7111P_RS23055	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XcvCFBP7111P_RS23080	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XcvCFBP7111P_RS23085	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XcvCFBP7111P_RS23145	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XcvCFBP7111P_RS23160	COG0129	dihydroxy-acid dehydratase activity
XcvCFBP7111P_RS23215	COG1733	regulation of RNA biosynthetic process
XcvCFBP7111P_RS23220	COG0702	epimerase
XcvCFBP7111P_RS23255	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS23260	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcvCFBP7111P_RS23265	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XcvCFBP7111P_RS23285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7111P_RS23290	COG2205	protein histidine kinase activity
XcvCFBP7111P_RS23295	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7111P_RS23315	COG1902	pentaerythritol trinitrate reductase activity
XcvCFBP7111P_RS23320	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XcvCFBP7111P_RS23325	COG2267	carboxylic ester hydrolase activity
XcvCFBP7111P_RS23340	COG2814	Major facilitator Superfamily
XcvCFBP7111P_RS23345	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS23355	COG0084	hydrolase, TatD family'
XcvCFBP7111P_RS23380	COG2252	PERMEase
XcvCFBP7111P_RS23415	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS23425	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XcvCFBP7111P_RS23445	COG2072	flavoprotein involved in K transport
XcvCFBP7111P_RS23450	COG2351	hydroxyisourate hydrolase activity
XcvCFBP7111P_RS23455	COG4807	Protein conserved in bacteria
XcvCFBP7111P_RS23465	COG1643	Atp-dependent helicase
XcvCFBP7111P_RS23480	COG1187	pseudouridine synthase activity
XcvCFBP7111P_RS23495	COG2130	NADP-dependent
XcvCFBP7111P_RS23525	COG1764	response to oxidative stress
XcvCFBP7111P_RS23530	COG1846	Transcriptional regulator
XcvCFBP7111P_RS23535	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XcvCFBP7111P_RS23545	COG0697	spore germination
XcvCFBP7111P_RS23620	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7111P_RS23625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XcvCFBP7111P_RS23630	COG4770	biotin carboxylase activity
XcvCFBP7111P_RS23660	COG2224	Isocitrate lyase
XcvCFBP7111P_RS23665	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XcvCFBP7111P_RS23670	COG0583	DNA-binding transcription factor activity
XcvCFBP7111P_RS23675	COG0475	glutathione-regulated potassium exporter activity
XcvCFBP7111P_RS23705	COG0339	signal peptide processing
XcvCFBP7111P_RS23710	COG1446	asparaginase
XcvCFBP7111P_RS23730	COG0564	pseudouridine synthase activity
XcvCFBP7111P_RS23740	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcvCFBP7111P_RS23755	COG1181	Belongs to the D-alanine--D-alanine ligase family
XcvCFBP7111P_RS23770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcvCFBP7111P_RS23780	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7111P_RS23785	COG0318	PFAM AMP-dependent synthetase and ligase
XcvCFBP7111P_RS23790	COG0727	PFAM Uncharacterised protein family (UPF0153)
XcvCFBP7111P_RS23795	COG0596	Alpha beta hydrolase
XcvCFBP7111P_RS23805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcvCFBP7111P_RS23820	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XcvCFBP7111P_RS23845	COG2205	protein histidine kinase activity
XcvCFBP7111P_RS23850	COG0028	Belongs to the TPP enzyme family
XcvCFBP7111P_RS23865	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XcvCFBP7111P_RS23870	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XcvCFBP7111P_RS23875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XcvCFBP7111P_RS23910	COG0183	Belongs to the thiolase family
XcvCFBP7111P_RS23920	COG0346	lactoylglutathione lyase activity
XcvCFBP7111P_RS23925	COG2032	superoxide dismutase activity
XcvCFBP7111P_RS23930	COG2032	superoxide dismutase activity
XcvCFBP7111P_RS23935	COG2204	response regulator
XcvCFBP7111P_RS23940	COG3852	Histidine kinase
XcvCFBP7111P_RS23945	COG0004	ammonium transporteR
XcvCFBP7111P_RS23950	COG0347	Belongs to the P(II) protein family
XcvCFBP7111P_RS23955	COG0174	glutamine synthetase
XcvCFBP7111P_RS23965	COG1968	undecaprenyl-diphosphatase activity
XcvCFBP7111P_RS24010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcvCFBP7111P_RS24020	COG2062	phosphohistidine phosphatase, SixA
XcvCFBP7111P_RS24025	COG0489	protein tyrosine kinase activity
XcvCFBP7111P_RS24055	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcvCFBP7111P_RS24070	COG1125	glycine betaine transport
XcvCFBP7111P_RS24070	COG0517	IMP dehydrogenase activity
XcvCFBP7111P_RS24085	COG1119	ATPase activity
XcvCFBP7111P_RS24095	COG1752	Esterase of the alpha-beta hydrolase superfamily
XcvCFBP7111P_RS24105	COG1522	sequence-specific DNA binding
XcvCFBP7111P_RS24110	COG3186	Phenylalanine-4-hydroxylase
XcvCFBP7111P_RS24120	COG2755	lipolytic protein G-D-S-L family
XcvCFBP7111P_RS24130	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS24135	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XcvCFBP7111P_RS24150	COG1609	Transcriptional regulator
XcvCFBP7111P_RS24155	COG3507	Belongs to the glycosyl hydrolase 43 family
XcvCFBP7111P_RS24170	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XcvCFBP7111P_RS24180	COG2755	lipolytic protein G-D-S-L family
XcvCFBP7111P_RS24180	COG0657	acetylesterase activity
XcvCFBP7111P_RS24200	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcvCFBP7111P_RS24210	COG0366	Alpha amylase catalytic
XcvCFBP7111P_RS24260	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7111P_RS24300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XcvCFBP7111P_RS24305	COG1074	ATP-dependent DNA helicase activity
XcvCFBP7111P_RS24310	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XcvCFBP7111P_RS24345	COG1127	ABC transporter
XcvCFBP7111P_RS24350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcvCFBP7111P_RS24355	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcvCFBP7111P_RS24370	COG2853	Lipoprotein
XcvCFBP7111P_RS24380	COG0386	Belongs to the glutathione peroxidase family
XcvCFBP7111P_RS24390	COG1322	Protein conserved in bacteria
XcvCFBP7111P_RS24400	COG0625	glutathione transferase activity
XcvCFBP7111P_RS24410	COG0531	amino acid
XcvCFBP7111P_RS24415	COG3537	Alpha-1,2-mannosidase
XcvCFBP7111P_RS24430	COG3706	GGDEF domain
XcvCFBP7111P_RS24435	COG3835	regulator
XcvCFBP7111P_RS24440	COG1929	Belongs to the glycerate kinase type-1 family
XcvCFBP7111P_RS24445	COG2271	Major facilitator Superfamily
XcvCFBP7111P_RS24460	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcvCFBP7111P_RS24465	COG0861	Integral membrane protein TerC family
XcvCFBP7111P_RS24475	COG0584	glycerophosphoryl diester phosphodiesterase
XcvCFBP7111P_RS24490	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XcvCFBP7111P_RS24500	COG0706	membrane insertase activity
XcvCFBP7111P_RS24505	COG0594	ribonuclease P activity
XcvCFBP7111P_RS24660	COG0305	Participates in initiation and elongation during chromosome replication
XcvCFBP7111P_RS24820	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XcvCFBP7111P_RS24845	COG3002	Belongs to the UPF0753 family
XcvCFBP7111P_RS24860	COG3318	Belongs to the UPF0149 family
XcvCFBP7111P_RS24860	COG3012	SEC-C Motif Domain Protein
XcvCFBP7111P_RS25000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XcvCFBP7111P_RS25115	COG1192	Involved in chromosome partitioning
XcvCFBP7111P_RS25120	COG1475	DNA binding
XcvCFBP7111P_RS25185	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcvCFBP7111P_RS25350	COG1475	DNA binding
XcvCFBP7111P_RS25465	COG3318	Belongs to the UPF0149 family
XcvCFBP7111P_RS25465	COG3012	SEC-C Motif Domain Protein
XcvCFBP7111P_RS25500	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XcvCFBP7111P_RS25585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XcvCFBP7111P_RS25640	COG2951	lytic endotransglycosylase activity
XcvCFBP7111P_RS25655	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XcvCFBP7111P_RS25660	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XcvCFBP7111P_RS25715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcvCFBP7111P_RS25810	COG1196	nuclear chromosome segregation
XcvCFBP7111P_RS25905	COG4644	lycopene metabolic process
XcvCFBP7111P_RS25915	COG2951	lytic endotransglycosylase activity
XcvCFBP7111P_RS25930	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XcvCFBP7111P_RS25935	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XcvCFBP7111P_RS25945	COG0776	regulation of translation