locus-tag	class	description
XcvCFBP7112P_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XcvCFBP7112P_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XcvCFBP7112P_RS00020	COG0187	DNA topoisomerase II activity
XcvCFBP7112P_RS00030	COG0501	Belongs to the peptidase M48B family
XcvCFBP7112P_RS00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XcvCFBP7112P_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcvCFBP7112P_RS00125	COG0793	Belongs to the peptidase S41A family
XcvCFBP7112P_RS00130	COG4942	peptidase
XcvCFBP7112P_RS00140	COG2234	aminopeptidase activity
XcvCFBP7112P_RS00150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcvCFBP7112P_RS00155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcvCFBP7112P_RS00165	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcvCFBP7112P_RS00175	COG1064	alcohol dehydrogenase
XcvCFBP7112P_RS00190	COG0493	'glutamate synthase
XcvCFBP7112P_RS00195	COG0067	glutamate synthase
XcvCFBP7112P_RS00195	COG0069	glutamate synthase activity
XcvCFBP7112P_RS00195	COG0070	glutamate synthase
XcvCFBP7112P_RS00285	COG1205	dead DEAH box helicase
XcvCFBP7112P_RS00285	COG1111	helicase
XcvCFBP7112P_RS00310	COG0300	oxidoreductase activity
XcvCFBP7112P_RS00315	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS00340	COG2249	NAD(P)H dehydrogenase (quinone) activity
XcvCFBP7112P_RS00410	COG3237	CsbD-like
XcvCFBP7112P_RS00460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcvCFBP7112P_RS00470	COG0477	Major facilitator Superfamily
XcvCFBP7112P_RS00505	COG4221	oxidoreductase activity
XcvCFBP7112P_RS00515	COG4221	oxidoreductase activity
XcvCFBP7112P_RS00520	COG1012	belongs to the aldehyde dehydrogenase family
XcvCFBP7112P_RS00550	COG0714	Associated with various cellular activities
XcvCFBP7112P_RS00585	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XcvCFBP7112P_RS00595	COG4772	TonB-dependent receptor
XcvCFBP7112P_RS00610	COG1012	belongs to the aldehyde dehydrogenase family
XcvCFBP7112P_RS00635	COG1304	FMN binding
XcvCFBP7112P_RS00650	COG4585	Histidine kinase
XcvCFBP7112P_RS00655	COG2197	response regulator
XcvCFBP7112P_RS00680	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XcvCFBP7112P_RS00805	COG0366	Alpha amylase catalytic
XcvCFBP7112P_RS00810	COG0366	Alpha amylase catalytic
XcvCFBP7112P_RS00815	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcvCFBP7112P_RS00830	COG2272	Belongs to the type-B carboxylesterase lipase family
XcvCFBP7112P_RS00835	COG2755	lipolytic protein G-D-S-L family
XcvCFBP7112P_RS00835	COG0657	acetylesterase activity
XcvCFBP7112P_RS00845	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XcvCFBP7112P_RS00860	COG3507	Belongs to the glycosyl hydrolase 43 family
XcvCFBP7112P_RS00865	COG1609	Transcriptional regulator
XcvCFBP7112P_RS00880	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XcvCFBP7112P_RS00885	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS00895	COG2755	lipolytic protein G-D-S-L family
XcvCFBP7112P_RS00905	COG3186	Phenylalanine-4-hydroxylase
XcvCFBP7112P_RS00910	COG1522	sequence-specific DNA binding
XcvCFBP7112P_RS00920	COG1752	Esterase of the alpha-beta hydrolase superfamily
XcvCFBP7112P_RS00930	COG1119	ATPase activity
XcvCFBP7112P_RS00945	COG1125	glycine betaine transport
XcvCFBP7112P_RS00960	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcvCFBP7112P_RS00995	COG0489	protein tyrosine kinase activity
XcvCFBP7112P_RS01000	COG2062	phosphohistidine phosphatase, SixA
XcvCFBP7112P_RS01010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcvCFBP7112P_RS01055	COG1968	undecaprenyl-diphosphatase activity
XcvCFBP7112P_RS01065	COG0174	glutamine synthetase
XcvCFBP7112P_RS01070	COG0347	Belongs to the P(II) protein family
XcvCFBP7112P_RS01075	COG0004	ammonium transporteR
XcvCFBP7112P_RS01080	COG3852	Histidine kinase
XcvCFBP7112P_RS01085	COG2204	response regulator
XcvCFBP7112P_RS01090	COG2032	superoxide dismutase activity
XcvCFBP7112P_RS01095	COG2032	superoxide dismutase activity
XcvCFBP7112P_RS01110	COG0183	Belongs to the thiolase family
XcvCFBP7112P_RS01145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XcvCFBP7112P_RS01150	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XcvCFBP7112P_RS01155	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XcvCFBP7112P_RS01170	COG0028	Belongs to the TPP enzyme family
XcvCFBP7112P_RS01175	COG2205	protein histidine kinase activity
XcvCFBP7112P_RS01200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XcvCFBP7112P_RS01215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcvCFBP7112P_RS01225	COG0596	Alpha beta hydrolase
XcvCFBP7112P_RS01230	COG0727	PFAM Uncharacterised protein family (UPF0153)
XcvCFBP7112P_RS01235	COG0318	PFAM AMP-dependent synthetase and ligase
XcvCFBP7112P_RS01250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcvCFBP7112P_RS01265	COG1181	Belongs to the D-alanine--D-alanine ligase family
XcvCFBP7112P_RS01280	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcvCFBP7112P_RS01290	COG0564	pseudouridine synthase activity
XcvCFBP7112P_RS01310	COG1446	asparaginase
XcvCFBP7112P_RS01315	COG0339	signal peptide processing
XcvCFBP7112P_RS01355	COG0475	glutathione-regulated potassium exporter activity
XcvCFBP7112P_RS01360	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS01365	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XcvCFBP7112P_RS01370	COG2224	Isocitrate lyase
XcvCFBP7112P_RS01400	COG4770	biotin carboxylase activity
XcvCFBP7112P_RS01405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XcvCFBP7112P_RS01410	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7112P_RS01480	COG0697	spore germination
XcvCFBP7112P_RS01490	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XcvCFBP7112P_RS01495	COG1846	Transcriptional regulator
XcvCFBP7112P_RS01500	COG1764	response to oxidative stress
XcvCFBP7112P_RS01530	COG2130	NADP-dependent
XcvCFBP7112P_RS01545	COG1187	pseudouridine synthase activity
XcvCFBP7112P_RS01560	COG1643	Atp-dependent helicase
XcvCFBP7112P_RS01570	COG4807	Protein conserved in bacteria
XcvCFBP7112P_RS01575	COG2351	hydroxyisourate hydrolase activity
XcvCFBP7112P_RS01580	COG2072	flavoprotein involved in K transport
XcvCFBP7112P_RS01600	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XcvCFBP7112P_RS01645	COG2252	PERMEase
XcvCFBP7112P_RS01670	COG0084	hydrolase, TatD family'
XcvCFBP7112P_RS01680	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS01685	COG2814	Major facilitator Superfamily
XcvCFBP7112P_RS01695	COG2267	carboxylic ester hydrolase activity
XcvCFBP7112P_RS01700	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XcvCFBP7112P_RS01705	COG1902	pentaerythritol trinitrate reductase activity
XcvCFBP7112P_RS01725	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_RS01730	COG2205	protein histidine kinase activity
XcvCFBP7112P_RS01735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7112P_RS01760	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcvCFBP7112P_RS01765	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS01800	COG0702	epimerase
XcvCFBP7112P_RS01805	COG1733	regulation of RNA biosynthetic process
XcvCFBP7112P_RS01850	COG0129	dihydroxy-acid dehydratase activity
XcvCFBP7112P_RS01865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XcvCFBP7112P_RS01920	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XcvCFBP7112P_RS01925	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XcvCFBP7112P_RS01950	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XcvCFBP7112P_RS01955	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XcvCFBP7112P_RS01965	COG3485	protocatechuate 3,4-dioxygenase
XcvCFBP7112P_RS01970	COG3485	protocatechuate 3,4-dioxygenase
XcvCFBP7112P_RS01980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcvCFBP7112P_RS01985	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XcvCFBP7112P_RS01995	COG1414	Transcriptional regulator
XcvCFBP7112P_RS02005	COG0657	acetylesterase activity
XcvCFBP7112P_RS02015	COG0445	tRNA wobble uridine modification
XcvCFBP7112P_RS02025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XcvCFBP7112P_RS02050	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS02055	COG2267	carboxylic ester hydrolase activity
XcvCFBP7112P_RS02065	COG0156	8-amino-7-oxononanoate synthase activity
XcvCFBP7112P_RS02070	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XcvCFBP7112P_RS02075	COG1040	competence protein
XcvCFBP7112P_RS02080	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XcvCFBP7112P_RS02120	COG5297	Belongs to the glycosyl hydrolase family 6
XcvCFBP7112P_RS02170	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XcvCFBP7112P_RS02245	COG3264	Mechanosensitive ion channel
XcvCFBP7112P_RS02245	COG1511	domain protein
XcvCFBP7112P_RS02250	COG1368	sulfuric ester hydrolase activity
XcvCFBP7112P_RS02260	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcvCFBP7112P_RS02265	COG2354	Protein conserved in bacteria
XcvCFBP7112P_RS02275	COG0297	glycogen (starch) synthase activity
XcvCFBP7112P_RS02280	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcvCFBP7112P_RS02285	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcvCFBP7112P_RS02310	COG0702	epimerase
XcvCFBP7112P_RS02315	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS02350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7112P_RS02365	COG0513	Belongs to the DEAD box helicase family
XcvCFBP7112P_RS02370	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcvCFBP7112P_RS02395	COG3483	tryptophan 2,3-dioxygenase activity
XcvCFBP7112P_RS02400	COG3104	oligopeptide transport
XcvCFBP7112P_RS02420	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XcvCFBP7112P_RS02440	COG1320	monovalent cation:proton antiporter activity
XcvCFBP7112P_RS02445	COG2212	antiporter activity
XcvCFBP7112P_RS02455	COG0651	ATP synthesis coupled electron transport
XcvCFBP7112P_RS02460	COG1006	Multisubunit Na H antiporter MnhC subunit
XcvCFBP7112P_RS02465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcvCFBP7112P_RS02465	COG2111	Na H antiporter
XcvCFBP7112P_RS02490	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XcvCFBP7112P_RS02495	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XcvCFBP7112P_RS02510	COG0456	acetyltransferase
XcvCFBP7112P_RS02515	COG1597	lipid kinase activity
XcvCFBP7112P_RS02540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XcvCFBP7112P_RS02545	COG0134	indole-3-glycerol-phosphate synthase activity
XcvCFBP7112P_RS02555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcvCFBP7112P_RS02560	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XcvCFBP7112P_RS02570	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XcvCFBP7112P_RS02580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XcvCFBP7112P_RS02595	COG1051	belongs to the nudix hydrolase family
XcvCFBP7112P_RS02635	COG0316	Belongs to the HesB IscA family
XcvCFBP7112P_RS02655	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcvCFBP7112P_RS02675	COG2814	Major facilitator Superfamily
XcvCFBP7112P_RS02685	COG2814	Major facilitator Superfamily
XcvCFBP7112P_RS02690	COG1289	transmembrane transporter activity
XcvCFBP7112P_RS02695	COG0151	Belongs to the GarS family
XcvCFBP7112P_RS02705	COG0138	bifunctional purine biosynthesis protein purh
XcvCFBP7112P_RS02710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcvCFBP7112P_RS02715	COG2267	carboxylic ester hydrolase activity
XcvCFBP7112P_RS02720	COG0671	phosphoesterase, PA-phosphatase related
XcvCFBP7112P_RS02720	COG2453	phosphatase
XcvCFBP7112P_RS02745	COG4589	Belongs to the CDS family
XcvCFBP7112P_RS02750	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XcvCFBP7112P_RS02775	COG2264	protein methyltransferase activity
XcvCFBP7112P_RS02795	COG0439	Biotin carboxylase
XcvCFBP7112P_RS02805	COG0511	ligase activity, forming carbon-carbon bonds
XcvCFBP7112P_RS02810	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XcvCFBP7112P_RS02820	COG1324	tolerance protein
XcvCFBP7112P_RS02850	COG0300	oxidoreductase activity
XcvCFBP7112P_RS02855	COG2356	endonuclease I
XcvCFBP7112P_RS02865	COG0459	protein refolding
XcvCFBP7112P_RS02870	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XcvCFBP7112P_RS02900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XcvCFBP7112P_RS02915	COG3386	PFAM SMP-30 Gluconolaconase
XcvCFBP7112P_RS02925	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XcvCFBP7112P_RS02955	COG0778	Nitroreductase
XcvCFBP7112P_RS02960	COG2353	YceI-like domain
XcvCFBP7112P_RS02990	COG3052	prosthetic group binding
XcvCFBP7112P_RS03015	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcvCFBP7112P_RS03025	COG1802	Transcriptional regulator
XcvCFBP7112P_RS03145	COG1082	Xylose isomerase domain protein TIM barrel
XcvCFBP7112P_RS03155	COG4221	oxidoreductase activity
XcvCFBP7112P_RS03165	COG0435	Glutathione S-transferase
XcvCFBP7112P_RS03200	COG1506	peptidase
XcvCFBP7112P_RS03200	COG0823	Involved in the tonB-independent uptake of proteins
XcvCFBP7112P_RS03245	COG0697	spore germination
XcvCFBP7112P_RS03250	COG4305	rare lipoprotein A
XcvCFBP7112P_RS03255	COG5297	Belongs to the glycosyl hydrolase family 6
XcvCFBP7112P_RS03265	COG1113	amino acid transport
XcvCFBP7112P_RS03285	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
XcvCFBP7112P_RS03335	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS03340	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcvCFBP7112P_RS03340	COG5297	Belongs to the glycosyl hydrolase family 6
XcvCFBP7112P_RS03345	COG0659	secondary active sulfate transmembrane transporter activity
XcvCFBP7112P_RS03370	COG2943	transferase activity, transferring hexosyl groups
XcvCFBP7112P_RS03380	COG3275	phosphorelay sensor kinase activity
XcvCFBP7112P_RS03390	COG0181	hydroxymethylbilane synthase activity
XcvCFBP7112P_RS03420	COG1505	serine-type exopeptidase activity
XcvCFBP7112P_RS03425	COG0436	Aminotransferase
XcvCFBP7112P_RS03435	COG2832	Protein of unknown function (DUF454)
XcvCFBP7112P_RS03445	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XcvCFBP7112P_RS03455	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XcvCFBP7112P_RS03460	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XcvCFBP7112P_RS03465	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XcvCFBP7112P_RS03490	COG2226	methyltransferase
XcvCFBP7112P_RS03495	COG3300	MHYT domain
XcvCFBP7112P_RS03495	COG5001	Diguanylate cyclase
XcvCFBP7112P_RS03500	COG0308	aminopeptidase N
XcvCFBP7112P_RS03550	COG3284	Transcriptional regulator
XcvCFBP7112P_RS03555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcvCFBP7112P_RS03560	COG1077	Cell shape determining protein MreB Mrl
XcvCFBP7112P_RS03565	COG1792	Involved in formation and maintenance of cell shape
XcvCFBP7112P_RS03580	COG0772	Belongs to the SEDS family
XcvCFBP7112P_RS03590	COG2951	lytic endotransglycosylase activity
XcvCFBP7112P_RS03595	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XcvCFBP7112P_RS03605	COG1686	Belongs to the peptidase S11 family
XcvCFBP7112P_RS03615	COG2921	Belongs to the UPF0250 family
XcvCFBP7112P_RS03620	COG0321	lipoyl(octanoyl) transferase activity
XcvCFBP7112P_RS03625	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XcvCFBP7112P_RS03640	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS03650	COG1051	belongs to the nudix hydrolase family
XcvCFBP7112P_RS03650	COG1056	cytidyltransferase-related domain
XcvCFBP7112P_RS03685	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XcvCFBP7112P_RS03690	COG0673	inositol 2-dehydrogenase activity
XcvCFBP7112P_RS03695	COG2823	Periplasmic or secreted lipoprotein
XcvCFBP7112P_RS03700	COG4251	negative regulation of phosphorylation
XcvCFBP7112P_RS03705	COG0784	Response regulator, receiver
XcvCFBP7112P_RS03710	COG4191	Histidine kinase
XcvCFBP7112P_RS03715	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XcvCFBP7112P_RS03770	COG1459	type II secretion system
XcvCFBP7112P_RS03775	COG2165	general secretion pathway protein
XcvCFBP7112P_RS03790	COG4795	General secretion pathway protein
XcvCFBP7112P_RS03820	COG3250	beta-galactosidase activity
XcvCFBP7112P_RS03835	COG2188	Transcriptional regulator
XcvCFBP7112P_RS03845	COG1609	Transcriptional regulator
XcvCFBP7112P_RS03850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcvCFBP7112P_RS03855	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XcvCFBP7112P_RS03870	COG0617	tRNA 3'-terminal CCA addition
XcvCFBP7112P_RS03875	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcvCFBP7112P_RS03880	COG1012	belongs to the aldehyde dehydrogenase family
XcvCFBP7112P_RS03900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcvCFBP7112P_RS03915	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XcvCFBP7112P_RS03920	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcvCFBP7112P_RS03940	COG2205	protein histidine kinase activity
XcvCFBP7112P_RS03970	COG3791	Glutathione-dependent formaldehyde-activating
XcvCFBP7112P_RS03985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcvCFBP7112P_RS03995	COG0697	spore germination
XcvCFBP7112P_RS04005	COG0488	(ABC) transporter
XcvCFBP7112P_RS04015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XcvCFBP7112P_RS04020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XcvCFBP7112P_RS04030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcvCFBP7112P_RS04030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcvCFBP7112P_RS04050	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XcvCFBP7112P_RS04055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcvCFBP7112P_RS04060	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XcvCFBP7112P_RS04090	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XcvCFBP7112P_RS04095	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XcvCFBP7112P_RS04100	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XcvCFBP7112P_RS04105	COG2205	protein histidine kinase activity
XcvCFBP7112P_RS04110	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_RS04115	COG0277	FAD linked oxidase domain protein
XcvCFBP7112P_RS04120	COG1988	membrane-bound metal-dependent
XcvCFBP7112P_RS04125	COG0792	nuclease activity
XcvCFBP7112P_RS04155	COG0275	rRNA processing
XcvCFBP7112P_RS04160	COG3116	cell division
XcvCFBP7112P_RS04170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XcvCFBP7112P_RS04175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XcvCFBP7112P_RS04180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcvCFBP7112P_RS04190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XcvCFBP7112P_RS04195	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcvCFBP7112P_RS04200	COG1181	Belongs to the D-alanine--D-alanine ligase family
XcvCFBP7112P_RS04205	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XcvCFBP7112P_RS04220	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XcvCFBP7112P_RS04230	COG0739	heme binding
XcvCFBP7112P_RS04235	COG0653	protein targeting
XcvCFBP7112P_RS04240	COG0494	nUDIX hydrolase
XcvCFBP7112P_RS04250	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XcvCFBP7112P_RS04265	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS04265	COG3321	synthase
XcvCFBP7112P_RS04265	COG0604	alcohol dehydrogenase
XcvCFBP7112P_RS04290	COG0366	Alpha amylase catalytic
XcvCFBP7112P_RS04330	COG2226	methyltransferase
XcvCFBP7112P_RS04335	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XcvCFBP7112P_RS04345	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XcvCFBP7112P_RS04385	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XcvCFBP7112P_RS04395	COG4106	trans-aconitate 2-methyltransferase activity
XcvCFBP7112P_RS04400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcvCFBP7112P_RS04410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcvCFBP7112P_RS04415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XcvCFBP7112P_RS04425	COG0667	Aldo Keto reductase
XcvCFBP7112P_RS04435	COG4771	TonB-dependent receptor
XcvCFBP7112P_RS04455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcvCFBP7112P_RS04460	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XcvCFBP7112P_RS04470	COG2175	clavaminate synthase activity
XcvCFBP7112P_RS04480	COG4181	ATPase activity
XcvCFBP7112P_RS04495	COG0642	Histidine kinase
XcvCFBP7112P_RS04505	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XcvCFBP7112P_RS04525	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XcvCFBP7112P_RS04530	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XcvCFBP7112P_RS04545	COG3829	transcription factor binding
XcvCFBP7112P_RS04555	COG1116	anion transmembrane transporter activity
XcvCFBP7112P_RS04560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcvCFBP7112P_RS04570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcvCFBP7112P_RS04575	COG0431	NADPH-dependent FMN reductase
XcvCFBP7112P_RS04595	COG0747	negative chemotaxis
XcvCFBP7112P_RS04605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XcvCFBP7112P_RS04615	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XcvCFBP7112P_RS04620	COG2967	ApaG domain
XcvCFBP7112P_RS04625	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XcvCFBP7112P_RS04630	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XcvCFBP7112P_RS04635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcvCFBP7112P_RS04640	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XcvCFBP7112P_RS04645	COG0123	including yeast histone deacetylase and acetoin utilization protein
XcvCFBP7112P_RS04650	COG2096	Adenosyltransferase
XcvCFBP7112P_RS04665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcvCFBP7112P_RS04670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcvCFBP7112P_RS04700	COG3384	dioxygenase
XcvCFBP7112P_RS04705	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS04720	COG1024	Enoyl-CoA hydratase
XcvCFBP7112P_RS04750	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XcvCFBP7112P_RS04775	COG0697	spore germination
XcvCFBP7112P_RS04785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcvCFBP7112P_RS04815	COG2197	response regulator
XcvCFBP7112P_RS04825	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XcvCFBP7112P_RS04835	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XcvCFBP7112P_RS04840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcvCFBP7112P_RS04850	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS04855	COG3634	alkyl hydroperoxide reductase activity
XcvCFBP7112P_RS04865	COG2890	protein-(glutamine-N5) methyltransferase activity
XcvCFBP7112P_RS04885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcvCFBP7112P_RS04885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcvCFBP7112P_RS04915	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XcvCFBP7112P_RS04955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcvCFBP7112P_RS04960	COG1404	Belongs to the peptidase S8 family
XcvCFBP7112P_RS04970	COG1404	Belongs to the peptidase S8 family
XcvCFBP7112P_RS04975	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XcvCFBP7112P_RS05000	COG1295	ribonuclease BN
XcvCFBP7112P_RS05005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcvCFBP7112P_RS05010	COG1254	Belongs to the acylphosphatase family
XcvCFBP7112P_RS05025	COG0521	Mo-molybdopterin cofactor biosynthetic process
XcvCFBP7112P_RS05035	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XcvCFBP7112P_RS05040	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XcvCFBP7112P_RS05050	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XcvCFBP7112P_RS05055	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XcvCFBP7112P_RS05065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XcvCFBP7112P_RS05070	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XcvCFBP7112P_RS05075	COG0193	aminoacyl-tRNA hydrolase activity
XcvCFBP7112P_RS05080	COG0012	GTP binding
XcvCFBP7112P_RS05100	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcvCFBP7112P_RS05115	COG0250	Participates in transcription elongation, termination and antitermination
XcvCFBP7112P_RS05120	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XcvCFBP7112P_RS05125	COG0081	regulation of translation
XcvCFBP7112P_RS05130	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XcvCFBP7112P_RS05135	COG0222	ribosome binding
XcvCFBP7112P_RS05140	COG0085	RNA polymerase activity
XcvCFBP7112P_RS05145	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XcvCFBP7112P_RS05150	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XcvCFBP7112P_RS05155	COG0049	tRNA binding
XcvCFBP7112P_RS05160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XcvCFBP7112P_RS05165	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcvCFBP7112P_RS05170	COG0051	transcription antitermination factor activity, RNA binding
XcvCFBP7112P_RS05175	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XcvCFBP7112P_RS05180	COG0088	Forms part of the polypeptide exit tunnel
XcvCFBP7112P_RS05190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XcvCFBP7112P_RS05195	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XcvCFBP7112P_RS05205	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XcvCFBP7112P_RS05210	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XcvCFBP7112P_RS05215	COG0255	Belongs to the universal ribosomal protein uL29 family
XcvCFBP7112P_RS05220	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XcvCFBP7112P_RS05230	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XcvCFBP7112P_RS05235	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XcvCFBP7112P_RS05240	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XcvCFBP7112P_RS05245	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XcvCFBP7112P_RS05250	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XcvCFBP7112P_RS05255	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XcvCFBP7112P_RS05265	COG1841	ribosomal large subunit assembly
XcvCFBP7112P_RS05270	COG0200	Binds to the 23S rRNA
XcvCFBP7112P_RS05275	COG0201	protein transport
XcvCFBP7112P_RS05300	COG0203	ribosomal protein L17
XcvCFBP7112P_RS05305	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XcvCFBP7112P_RS05325	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XcvCFBP7112P_RS05340	COG0154	amidase activity
XcvCFBP7112P_RS05350	COG1217	gtp-binding protein TYPA
XcvCFBP7112P_RS05355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XcvCFBP7112P_RS05360	COG0039	L-malate dehydrogenase activity
XcvCFBP7112P_RS05365	COG0625	glutathione transferase activity
XcvCFBP7112P_RS05380	COG1902	pentaerythritol trinitrate reductase activity
XcvCFBP7112P_RS05380	COG0446	pyridine nucleotide-disulphide oxidoreductase
XcvCFBP7112P_RS05415	COG0156	8-amino-7-oxononanoate synthase activity
XcvCFBP7112P_RS05425	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XcvCFBP7112P_RS05430	COG4208	sulfate ABC transporter
XcvCFBP7112P_RS05435	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XcvCFBP7112P_RS05465	COG0406	alpha-ribazole phosphatase activity
XcvCFBP7112P_RS05470	COG0285	dihydrofolate synthase activity
XcvCFBP7112P_RS05490	COG2833	Protein of unknown function (DUF455)
XcvCFBP7112P_RS05510	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcvCFBP7112P_RS05515	COG0671	phosphoesterase, PA-phosphatase related
XcvCFBP7112P_RS05520	COG0438	transferase activity, transferring glycosyl groups
XcvCFBP7112P_RS05530	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XcvCFBP7112P_RS05545	COG4783	chaperone-mediated protein folding
XcvCFBP7112P_RS05560	COG0473	3-isopropylmalate dehydrogenase activity
XcvCFBP7112P_RS05790	COG3179	chitinase
XcvCFBP7112P_RS05835	COG4695	Portal protein
XcvCFBP7112P_RS05845	COG0863	Belongs to the N(4) N(6)-methyltransferase family
XcvCFBP7112P_RS05850	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XcvCFBP7112P_RS05880	COG0544	peptidyl-prolyl cis-trans isomerase activity
XcvCFBP7112P_RS05890	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XcvCFBP7112P_RS05920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcvCFBP7112P_RS05930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcvCFBP7112P_RS05940	COG0328	RNA-DNA hybrid ribonuclease activity
XcvCFBP7112P_RS05945	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcvCFBP7112P_RS05950	COG0631	protein serine/threonine phosphatase activity
XcvCFBP7112P_RS05965	COG0859	PFAM glycosyl transferase family 9
XcvCFBP7112P_RS05970	COG3642	lipopolysaccharide core region biosynthetic process
XcvCFBP7112P_RS05975	COG1234	tRNA 3'-trailer cleavage
XcvCFBP7112P_RS05980	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XcvCFBP7112P_RS05990	COG0315	cyclic pyranopterin monophosphate synthase activity
XcvCFBP7112P_RS05995	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XcvCFBP7112P_RS06000	COG0314	molybdopterin synthase activity
XcvCFBP7112P_RS06020	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XcvCFBP7112P_RS06025	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XcvCFBP7112P_RS06030	COG0537	adenosine 5'-monophosphoramidase activity
XcvCFBP7112P_RS06050	COG0714	Associated with various cellular activities
XcvCFBP7112P_RS06075	COG0424	maF-like protein
XcvCFBP7112P_RS06080	COG1399	metal-binding, possibly nucleic acid-binding protein
XcvCFBP7112P_RS06090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcvCFBP7112P_RS06100	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcvCFBP7112P_RS06120	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XcvCFBP7112P_RS06125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XcvCFBP7112P_RS06150	COG3829	transcription factor binding
XcvCFBP7112P_RS06165	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
XcvCFBP7112P_RS06195	COG2373	Large extracellular alpha-helical protein
XcvCFBP7112P_RS06215	COG4953	penicillin-binding protein 1C
XcvCFBP7112P_RS06225	COG0678	peroxiredoxin activity
XcvCFBP7112P_RS06245	COG0330	HflC and HflK could
XcvCFBP7112P_RS06250	COG0330	HflC and HflK could
XcvCFBP7112P_RS06260	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XcvCFBP7112P_RS06265	COG0308	aminopeptidase N
XcvCFBP7112P_RS06275	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS06280	COG1309	transcriptional regulator
XcvCFBP7112P_RS06335	COG0732	type I restriction modification DNA specificity domain
XcvCFBP7112P_RS06340	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XcvCFBP7112P_RS06385	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcvCFBP7112P_RS06400	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS06405	COG3537	Alpha-1,2-mannosidase
XcvCFBP7112P_RS06410	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS06425	COG0492	ferredoxin-NADP+ reductase activity
XcvCFBP7112P_RS06470	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcvCFBP7112P_RS06475	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcvCFBP7112P_RS06480	COG2080	2 iron, 2 sulfur cluster binding
XcvCFBP7112P_RS06515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcvCFBP7112P_RS06530	COG0587	DNA-directed DNA polymerase activity
XcvCFBP7112P_RS06560	COG1506	peptidase
XcvCFBP7112P_RS06560	COG0823	Involved in the tonB-independent uptake of proteins
XcvCFBP7112P_RS06580	COG1917	Cupin 2, conserved barrel domain protein
XcvCFBP7112P_RS06580	COG2207	Transcriptional regulator
XcvCFBP7112P_RS06600	COG0753	catalase activity
XcvCFBP7112P_RS06605	COG0656	L-ascorbic acid biosynthetic process
XcvCFBP7112P_RS06615	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcvCFBP7112P_RS06615	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcvCFBP7112P_RS06620	COG2814	Major facilitator Superfamily
XcvCFBP7112P_RS06635	COG2194	sulfuric ester hydrolase activity
XcvCFBP7112P_RS06650	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_RS06655	COG0642	Histidine kinase
XcvCFBP7112P_RS06665	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XcvCFBP7112P_RS06670	COG2894	cell division
XcvCFBP7112P_RS06675	COG0850	regulation of cytokinetic process
XcvCFBP7112P_RS06690	COG4585	Histidine kinase
XcvCFBP7112P_RS06695	COG2197	response regulator
XcvCFBP7112P_RS06710	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XcvCFBP7112P_RS06735	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XcvCFBP7112P_RS06745	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XcvCFBP7112P_RS06765	COG1946	Acyl-CoA thioesterase
XcvCFBP7112P_RS06780	COG0824	Thioesterase
XcvCFBP7112P_RS06785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XcvCFBP7112P_RS06790	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XcvCFBP7112P_RS06795	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XcvCFBP7112P_RS06800	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XcvCFBP7112P_RS06805	COG0268	Binds directly to 16S ribosomal RNA
XcvCFBP7112P_RS06815	COG0196	riboflavin kinase activity
XcvCFBP7112P_RS06820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XcvCFBP7112P_RS06825	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XcvCFBP7112P_RS06830	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XcvCFBP7112P_RS06865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XcvCFBP7112P_RS06870	COG1845	cytochrome c oxidase, subunit III
XcvCFBP7112P_RS06875	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XcvCFBP7112P_RS06900	COG2207	Transcriptional regulator
XcvCFBP7112P_RS06905	COG0326	Molecular chaperone. Has ATPase activity
XcvCFBP7112P_RS06915	COG1366	Belongs to the anti-sigma-factor antagonist family
XcvCFBP7112P_RS06925	COG2172	sigma factor antagonist activity
XcvCFBP7112P_RS06950	COG4771	TonB-dependent receptor
XcvCFBP7112P_RS06960	COG5507	3-demethylubiquinone-9 3-methyltransferase
XcvCFBP7112P_RS06970	COG2205	protein histidine kinase activity
XcvCFBP7112P_RS06980	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcvCFBP7112P_RS06985	COG4999	Histidine kinase
XcvCFBP7112P_RS06985	COG3850	Histidine kinase
XcvCFBP7112P_RS06985	COG2205	protein histidine kinase activity
XcvCFBP7112P_RS06985	COG3437	response regulator, receiver
XcvCFBP7112P_RS06990	COG0784	Response regulator, receiver
XcvCFBP7112P_RS06990	COG4191	Histidine kinase
XcvCFBP7112P_RS07015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcvCFBP7112P_RS07025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XcvCFBP7112P_RS07035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcvCFBP7112P_RS07040	COG0228	four-way junction DNA binding
XcvCFBP7112P_RS07045	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XcvCFBP7112P_RS07050	COG0336	Belongs to the RNA methyltransferase TrmD family
XcvCFBP7112P_RS07055	COG0335	large ribosomal subunit rRNA binding
XcvCFBP7112P_RS07060	COG0534	Mate efflux family protein
XcvCFBP7112P_RS07085	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XcvCFBP7112P_RS07095	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XcvCFBP7112P_RS07125	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XcvCFBP7112P_RS07135	COG0210	DNA helicase
XcvCFBP7112P_RS07195	COG3483	tryptophan 2,3-dioxygenase activity
XcvCFBP7112P_RS07205	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XcvCFBP7112P_RS07210	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS07235	COG3250	beta-galactosidase activity
XcvCFBP7112P_RS07240	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XcvCFBP7112P_RS07260	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7112P_RS07265	COG1024	Enoyl-CoA hydratase
XcvCFBP7112P_RS07270	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XcvCFBP7112P_RS07300	COG0457	Tetratricopeptide repeat
XcvCFBP7112P_RS07310	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcvCFBP7112P_RS07310	COG1024	Enoyl-CoA hydratase
XcvCFBP7112P_RS07325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcvCFBP7112P_RS07330	COG0481	GTPase activity
XcvCFBP7112P_RS07345	COG0571	ribonuclease III activity
XcvCFBP7112P_RS07350	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XcvCFBP7112P_RS07355	COG1381	Involved in DNA repair and RecF pathway recombination
XcvCFBP7112P_RS07365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XcvCFBP7112P_RS07370	COG2954	triphosphatase activity
XcvCFBP7112P_RS07375	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XcvCFBP7112P_RS07380	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XcvCFBP7112P_RS07385	COG3046	protein related to deoxyribodipyrimidine photolyase
XcvCFBP7112P_RS07390	COG1472	Belongs to the glycosyl hydrolase 3 family
XcvCFBP7112P_RS07395	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XcvCFBP7112P_RS07400	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XcvCFBP7112P_RS07405	COG1278	Cold shock
XcvCFBP7112P_RS07410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcvCFBP7112P_RS07420	COG1201	RNA secondary structure unwinding
XcvCFBP7112P_RS07425	COG1793	dna ligase
XcvCFBP7112P_RS07435	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcvCFBP7112P_RS07435	COG1793	dna ligase
XcvCFBP7112P_RS07465	COG0183	Belongs to the thiolase family
XcvCFBP7112P_RS07485	COG1451	nucleotide metabolic process
XcvCFBP7112P_RS07490	COG5487	UPF0391 membrane protein
XcvCFBP7112P_RS07500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XcvCFBP7112P_RS07515	COG1077	Cell shape determining protein MreB Mrl
XcvCFBP7112P_RS07520	COG1047	Peptidyl-prolyl cis-trans
XcvCFBP7112P_RS07530	COG2824	Alkylphosphonate utilization operon protein PhnA
XcvCFBP7112P_RS07540	COG1902	pentaerythritol trinitrate reductase activity
XcvCFBP7112P_RS07545	COG2814	Major facilitator Superfamily
XcvCFBP7112P_RS07580	COG0392	lysyltransferase activity
XcvCFBP7112P_RS07580	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XcvCFBP7112P_RS07590	COG0251	oxidation-reduction process
XcvCFBP7112P_RS07595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcvCFBP7112P_RS07610	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcvCFBP7112P_RS07635	COG1595	DNA-templated transcription, initiation
XcvCFBP7112P_RS07660	COG2878	Part of a membrane complex involved in electron transport
XcvCFBP7112P_RS07670	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcvCFBP7112P_RS07670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcvCFBP7112P_RS07685	COG1131	(ABC) transporter
XcvCFBP7112P_RS07690	COG0346	lactoylglutathione lyase activity
XcvCFBP7112P_RS07695	COG0833	amino acid
XcvCFBP7112P_RS07700	COG2040	homocysteine
XcvCFBP7112P_RS07710	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XcvCFBP7112P_RS07730	COG1695	Transcriptional regulator
XcvCFBP7112P_RS07750	COG1981	membrane
XcvCFBP7112P_RS07765	COG0825	malonyl-CoA metabolic process
XcvCFBP7112P_RS07780	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcvCFBP7112P_RS07785	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcvCFBP7112P_RS07790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcvCFBP7112P_RS07795	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcvCFBP7112P_RS07810	COG0750	zinc metalloprotease
XcvCFBP7112P_RS07815	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XcvCFBP7112P_RS07825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XcvCFBP7112P_RS07830	COG0233	cytoplasmic translational termination
XcvCFBP7112P_RS07835	COG0528	UMP kinase activity
XcvCFBP7112P_RS07845	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XcvCFBP7112P_RS07850	COG0052	Belongs to the universal ribosomal protein uS2 family
XcvCFBP7112P_RS07890	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XcvCFBP7112P_RS07900	COG1393	Belongs to the ArsC family
XcvCFBP7112P_RS07905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcvCFBP7112P_RS07910	COG0367	asparagine synthase
XcvCFBP7112P_RS07920	COG4774	siderophore transport
XcvCFBP7112P_RS07960	COG1566	PFAM secretion protein HlyD family protein
XcvCFBP7112P_RS07965	COG2814	Major facilitator Superfamily
XcvCFBP7112P_RS08020	COG0339	signal peptide processing
XcvCFBP7112P_RS08025	COG0386	Belongs to the glutathione peroxidase family
XcvCFBP7112P_RS08045	COG0625	glutathione transferase activity
XcvCFBP7112P_RS08080	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XcvCFBP7112P_RS08085	COG0084	hydrolase, TatD family'
XcvCFBP7112P_RS08100	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7112P_RS08120	COG0367	asparagine synthase
XcvCFBP7112P_RS08130	COG0305	Participates in initiation and elongation during chromosome replication
XcvCFBP7112P_RS08135	COG0415	Belongs to the DNA photolyase family
XcvCFBP7112P_RS08150	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS08195	COG3706	GGDEF domain
XcvCFBP7112P_RS08220	COG0582	viral genome integration into host DNA
XcvCFBP7112P_RS08235	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XcvCFBP7112P_RS08250	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcvCFBP7112P_RS08260	COG0497	DNA recombination
XcvCFBP7112P_RS08265	COG1420	regulation of RNA biosynthetic process
XcvCFBP7112P_RS08270	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XcvCFBP7112P_RS08275	COG0443	Heat shock 70 kDa protein
XcvCFBP7112P_RS08280	COG0484	heat shock protein binding
XcvCFBP7112P_RS08320	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS08325	COG1132	(ABC) transporter
XcvCFBP7112P_RS08350	COG0567	Dehydrogenase, E1 component
XcvCFBP7112P_RS08360	COG2850	peptidyl-arginine hydroxylation
XcvCFBP7112P_RS08380	COG1253	flavin adenine dinucleotide binding
XcvCFBP7112P_RS08415	COG1131	(ABC) transporter
XcvCFBP7112P_RS08420	COG1725	Transcriptional regulator
XcvCFBP7112P_RS08430	COG0386	Belongs to the glutathione peroxidase family
XcvCFBP7112P_RS08445	COG2900	Belongs to the SlyX family
XcvCFBP7112P_RS08470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcvCFBP7112P_RS08480	COG0646	methionine synthase
XcvCFBP7112P_RS08480	COG1410	methionine synthase
XcvCFBP7112P_RS08485	COG1410	methionine synthase
XcvCFBP7112P_RS08485	COG0646	methionine synthase
XcvCFBP7112P_RS08490	COG2226	methyltransferase
XcvCFBP7112P_RS08495	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7112P_RS08500	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7112P_RS08530	COG0557	exoribonuclease II activity
XcvCFBP7112P_RS08540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcvCFBP7112P_RS08550	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcvCFBP7112P_RS08560	COG0704	Plays a role in the regulation of phosphate uptake
XcvCFBP7112P_RS08565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XcvCFBP7112P_RS08570	COG0581	inorganic phosphate transmembrane transporter activity
XcvCFBP7112P_RS08575	COG0573	inorganic phosphate transmembrane transporter activity
XcvCFBP7112P_RS08580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XcvCFBP7112P_RS08605	COG0659	secondary active sulfate transmembrane transporter activity
XcvCFBP7112P_RS08610	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XcvCFBP7112P_RS08620	COG1024	Enoyl-CoA hydratase
XcvCFBP7112P_RS08630	COG0494	nUDIX hydrolase
XcvCFBP7112P_RS08665	COG0488	(ABC) transporter
XcvCFBP7112P_RS08675	COG0116	Belongs to the methyltransferase superfamily
XcvCFBP7112P_RS08675	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcvCFBP7112P_RS08680	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XcvCFBP7112P_RS08700	COG2925	Exonuclease
XcvCFBP7112P_RS08705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcvCFBP7112P_RS08710	COG3844	kynureninase activity
XcvCFBP7112P_RS08720	COG0662	Cupin 2, conserved barrel domain protein
XcvCFBP7112P_RS08725	COG0288	reversible hydration of carbon dioxide
XcvCFBP7112P_RS08805	COG0017	Asparaginyl-tRNA synthetase
XcvCFBP7112P_RS08815	COG0316	Belongs to the HesB IscA family
XcvCFBP7112P_RS08820	COG0360	Binds together with S18 to 16S ribosomal RNA
XcvCFBP7112P_RS08825	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XcvCFBP7112P_RS08830	COG0359	binds to the 23S rRNA
XcvCFBP7112P_RS08845	COG3115	cell septum assembly
XcvCFBP7112P_RS08855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcvCFBP7112P_RS08860	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XcvCFBP7112P_RS08865	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XcvCFBP7112P_RS08880	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XcvCFBP7112P_RS08890	COG4993	Dehydrogenase
XcvCFBP7112P_RS08900	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XcvCFBP7112P_RS08910	COG2986	histidine ammonia-lyase
XcvCFBP7112P_RS08915	COG1228	amidohydrolase
XcvCFBP7112P_RS08960	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XcvCFBP7112P_RS08965	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XcvCFBP7112P_RS08970	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XcvCFBP7112P_RS08975	COG0077	Prephenate dehydratase
XcvCFBP7112P_RS08975	COG1605	Chorismate mutase
XcvCFBP7112P_RS08980	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XcvCFBP7112P_RS08995	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XcvCFBP7112P_RS09000	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcvCFBP7112P_RS09005	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS09020	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS09055	COG4191	Histidine kinase
XcvCFBP7112P_RS09055	COG0784	Response regulator, receiver
XcvCFBP7112P_RS09070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcvCFBP7112P_RS09080	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcvCFBP7112P_RS09090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcvCFBP7112P_RS09105	COG1595	DNA-templated transcription, initiation
XcvCFBP7112P_RS09160	COG2244	polysaccharide biosynthetic process
XcvCFBP7112P_RS09190	COG2264	protein methyltransferase activity
XcvCFBP7112P_RS09215	COG1136	(ABC) transporter
XcvCFBP7112P_RS09230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcvCFBP7112P_RS09245	COG1253	flavin adenine dinucleotide binding
XcvCFBP7112P_RS09260	COG0306	phosphate transporter
XcvCFBP7112P_RS09285	COG0504	CTP synthase activity
XcvCFBP7112P_RS09300	COG0148	phosphopyruvate hydratase activity
XcvCFBP7112P_RS09305	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XcvCFBP7112P_RS09310	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XcvCFBP7112P_RS09315	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XcvCFBP7112P_RS09320	COG0585	pseudouridine synthase activity
XcvCFBP7112P_RS09325	COG2840	Smr protein MutS2
XcvCFBP7112P_RS09330	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XcvCFBP7112P_RS09335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcvCFBP7112P_RS09340	COG1238	metal cluster binding
XcvCFBP7112P_RS09355	COG1534	Rna-binding protein
XcvCFBP7112P_RS09360	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XcvCFBP7112P_RS09370	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XcvCFBP7112P_RS09375	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XcvCFBP7112P_RS09385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XcvCFBP7112P_RS09390	COG1546	Belongs to the CinA family
XcvCFBP7112P_RS09400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcvCFBP7112P_RS09405	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XcvCFBP7112P_RS09415	COG2137	regulation of response to DNA damage stimulus
XcvCFBP7112P_RS09420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XcvCFBP7112P_RS09425	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XcvCFBP7112P_RS09445	COG1741	Belongs to the pirin family
XcvCFBP7112P_RS09450	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS09475	COG0351	phosphomethylpyrimidine kinase
XcvCFBP7112P_RS09490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XcvCFBP7112P_RS09495	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XcvCFBP7112P_RS09510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcvCFBP7112P_RS09520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XcvCFBP7112P_RS09525	COG3734	2-keto-3-deoxy-galactonokinase
XcvCFBP7112P_RS09535	COG4948	Mandelate Racemase Muconate Lactonizing
XcvCFBP7112P_RS09540	COG0800	Aldolase
XcvCFBP7112P_RS09595	COG1501	Belongs to the glycosyl hydrolase 31 family
XcvCFBP7112P_RS09605	COG1070	Carbohydrate kinase
XcvCFBP7112P_RS09610	COG2115	Belongs to the xylose isomerase family
XcvCFBP7112P_RS09615	COG0477	Major facilitator Superfamily
XcvCFBP7112P_RS09640	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcvCFBP7112P_RS09645	COG1469	GTP cyclohydrolase I activity
XcvCFBP7112P_RS09665	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XcvCFBP7112P_RS09670	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XcvCFBP7112P_RS09675	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XcvCFBP7112P_RS09700	COG1472	Belongs to the glycosyl hydrolase 3 family
XcvCFBP7112P_RS09715	COG5001	Diguanylate cyclase
XcvCFBP7112P_RS09715	COG3706	GGDEF domain
XcvCFBP7112P_RS09715	COG4251	negative regulation of phosphorylation
XcvCFBP7112P_RS09715	COG2203	Gaf domain
XcvCFBP7112P_RS09730	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XcvCFBP7112P_RS09740	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XcvCFBP7112P_RS09745	COG0671	phosphoesterase, PA-phosphatase related
XcvCFBP7112P_RS09755	COG1794	racemase activity, acting on amino acids and derivatives
XcvCFBP7112P_RS09765	COG0697	spore germination
XcvCFBP7112P_RS09770	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XcvCFBP7112P_RS09775	COG0167	dihydroorotate dehydrogenase activity
XcvCFBP7112P_RS09790	COG1012	belongs to the aldehyde dehydrogenase family
XcvCFBP7112P_RS09810	COG1215	transferase activity, transferring glycosyl groups
XcvCFBP7112P_RS09815	COG1649	PFAM Uncharacterised BCR, COG1649
XcvCFBP7112P_RS09815	COG0726	polysaccharide deacetylase
XcvCFBP7112P_RS09830	COG3210	domain, Protein
XcvCFBP7112P_RS09830	COG3210	domain, Protein
XcvCFBP7112P_RS09840	COG3210	domain, Protein
XcvCFBP7112P_RS09860	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
XcvCFBP7112P_RS09895	COG0124	histidyl-tRNA synthetase
XcvCFBP7112P_RS09905	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XcvCFBP7112P_RS09910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XcvCFBP7112P_RS09915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcvCFBP7112P_RS09920	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XcvCFBP7112P_RS09920	COG0131	Imidazoleglycerol-phosphate dehydratase
XcvCFBP7112P_RS09925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XcvCFBP7112P_RS09930	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XcvCFBP7112P_RS09935	COG0107	imidazoleglycerol-phosphate synthase activity
XcvCFBP7112P_RS09940	COG0140	phosphoribosyl-ATP diphosphatase activity
XcvCFBP7112P_RS09940	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XcvCFBP7112P_RS09955	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XcvCFBP7112P_RS09960	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XcvCFBP7112P_RS09965	COG0235	Class ii aldolase
XcvCFBP7112P_RS09970	COG0531	amino acid
XcvCFBP7112P_RS09975	COG0531	amino acid
XcvCFBP7112P_RS09985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XcvCFBP7112P_RS09990	COG0277	FAD linked oxidase domain protein
XcvCFBP7112P_RS10010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcvCFBP7112P_RS10055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcvCFBP7112P_RS10060	COG2258	MOSC domain
XcvCFBP7112P_RS10065	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XcvCFBP7112P_RS10070	COG0505	Belongs to the CarA family
XcvCFBP7112P_RS10080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XcvCFBP7112P_RS10085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcvCFBP7112P_RS10130	COG3279	Response regulator of the LytR AlgR family
XcvCFBP7112P_RS10135	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XcvCFBP7112P_RS10140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XcvCFBP7112P_RS10150	COG2198	Histidine kinase
XcvCFBP7112P_RS10150	COG0784	Response regulator, receiver
XcvCFBP7112P_RS10150	COG2205	protein histidine kinase activity
XcvCFBP7112P_RS10155	COG2198	Histidine kinase
XcvCFBP7112P_RS10155	COG2205	protein histidine kinase activity
XcvCFBP7112P_RS10155	COG0784	Response regulator, receiver
XcvCFBP7112P_RS10160	COG1024	Enoyl-CoA hydratase
XcvCFBP7112P_RS10165	COG0318	PFAM AMP-dependent synthetase and ligase
XcvCFBP7112P_RS10195	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcvCFBP7112P_RS10205	COG2201	protein-glutamate methylesterase activity
XcvCFBP7112P_RS10210	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XcvCFBP7112P_RS10220	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS10235	COG0835	chemotaxis
XcvCFBP7112P_RS10260	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS10265	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS10275	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS10285	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS10295	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS10300	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS10305	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS10320	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS10345	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_RS10355	COG0835	chemotaxis
XcvCFBP7112P_RS10365	COG1360	Flagellar Motor Protein
XcvCFBP7112P_RS10370	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XcvCFBP7112P_RS10450	COG0784	Response regulator, receiver
XcvCFBP7112P_RS10450	COG2198	Histidine kinase
XcvCFBP7112P_RS10450	COG0643	Histidine kinase
XcvCFBP7112P_RS10510	COG1684	flagellar biosynthetic protein fliR
XcvCFBP7112P_RS10525	COG3190	flagellar
XcvCFBP7112P_RS10575	COG1677	Flagellar hook-basal body complex protein FliE
XcvCFBP7112P_RS10615	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS10620	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS10625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcvCFBP7112P_RS10645	COG2201	protein-glutamate methylesterase activity
XcvCFBP7112P_RS10675	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XcvCFBP7112P_RS10680	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XcvCFBP7112P_RS10685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XcvCFBP7112P_RS10695	COG1705	Flagellar rod assembly protein muramidase FlgJ
XcvCFBP7112P_RS10695	COG3951	Flagellar rod assembly protein muramidase FlgJ
XcvCFBP7112P_RS10700	COG1706	bacterial-type flagellum-dependent cell motility
XcvCFBP7112P_RS10705	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XcvCFBP7112P_RS10720	COG4787	bacterial-type flagellum-dependent cell motility
XcvCFBP7112P_RS10730	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XcvCFBP7112P_RS10735	COG1558	bacterial-type flagellum-dependent cell motility
XcvCFBP7112P_RS10745	COG0835	chemotaxis
XcvCFBP7112P_RS10745	COG0784	Response regulator, receiver
XcvCFBP7112P_RS10765	COG5002	protein histidine kinase activity
XcvCFBP7112P_RS10795	COG2915	High frequency lysogenization protein hflD homolog
XcvCFBP7112P_RS10800	COG0482	sulfurtransferase activity
XcvCFBP7112P_RS10815	COG0542	response to heat
XcvCFBP7112P_RS10825	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XcvCFBP7112P_RS10835	COG0492	ferredoxin-NADP+ reductase activity
XcvCFBP7112P_RS10840	COG1674	ftsk spoiiie
XcvCFBP7112P_RS10850	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XcvCFBP7112P_RS10860	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XcvCFBP7112P_RS10865	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XcvCFBP7112P_RS10875	COG0183	Belongs to the thiolase family
XcvCFBP7112P_RS10880	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcvCFBP7112P_RS10880	COG1024	Enoyl-CoA hydratase
XcvCFBP7112P_RS10895	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XcvCFBP7112P_RS10905	COG1426	Protein conserved in bacteria
XcvCFBP7112P_RS10915	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcvCFBP7112P_RS10920	COG1160	GTP binding
XcvCFBP7112P_RS10925	COG0303	'Molybdopterin
XcvCFBP7112P_RS10930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XcvCFBP7112P_RS10970	COG0708	Exodeoxyribonuclease III
XcvCFBP7112P_RS10980	COG0303	'Molybdopterin
XcvCFBP7112P_RS10985	COG0746	molybdenum cofactor guanylyltransferase activity
XcvCFBP7112P_RS11005	COG2072	flavoprotein involved in K transport
XcvCFBP7112P_RS11015	COG1914	H( )-stimulated, divalent metal cation uptake system
XcvCFBP7112P_RS11030	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XcvCFBP7112P_RS11035	COG0668	transmembrane transport
XcvCFBP7112P_RS11045	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XcvCFBP7112P_RS11060	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS11065	COG1183	phosphatidylcholine synthase activity
XcvCFBP7112P_RS11075	COG3243	poly(R)-hydroxyalkanoic acid synthase
XcvCFBP7112P_RS11090	COG0723	plastoquinol--plastocyanin reductase activity
XcvCFBP7112P_RS11090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcvCFBP7112P_RS11100	COG2183	response to ionizing radiation
XcvCFBP7112P_RS11105	COG0784	Response regulator, receiver
XcvCFBP7112P_RS11105	COG2205	protein histidine kinase activity
XcvCFBP7112P_RS11170	COG0800	Aldolase
XcvCFBP7112P_RS11175	COG0129	dihydroxy-acid dehydratase activity
XcvCFBP7112P_RS11180	COG0363	glucosamine-6-phosphate deaminase activity
XcvCFBP7112P_RS11185	COG0837	glucose binding
XcvCFBP7112P_RS11190	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcvCFBP7112P_RS11200	COG0354	folic acid binding
XcvCFBP7112P_RS11215	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XcvCFBP7112P_RS11230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XcvCFBP7112P_RS11235	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XcvCFBP7112P_RS11245	COG4591	ABC-type transport system involved in lipoprotein release permease component
XcvCFBP7112P_RS11250	COG1136	(ABC) transporter
XcvCFBP7112P_RS11265	COG0811	peptide transport
XcvCFBP7112P_RS11270	COG0848	biopolymer transport protein
XcvCFBP7112P_RS11275	COG1132	(ABC) transporter
XcvCFBP7112P_RS11280	COG1663	tetraacyldisaccharide 4'-kinase activity
XcvCFBP7112P_RS11285	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XcvCFBP7112P_RS11290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XcvCFBP7112P_RS11300	COG0322	excinuclease ABC activity
XcvCFBP7112P_RS11305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcvCFBP7112P_RS11330	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XcvCFBP7112P_RS11350	COG1054	Belongs to the UPF0176 family
XcvCFBP7112P_RS11360	COG1530	ribonuclease E activity
XcvCFBP7112P_RS11370	COG3064	Membrane
XcvCFBP7112P_RS11375	COG0428	transporter
XcvCFBP7112P_RS11385	COG2154	pterin-4-alpha-carbinolamine dehydratase
XcvCFBP7112P_RS11390	COG0316	Belongs to the HesB IscA family
XcvCFBP7112P_RS11390	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XcvCFBP7112P_RS11420	COG1073	alpha beta
XcvCFBP7112P_RS11420	COG2226	methyltransferase
XcvCFBP7112P_RS11425	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcvCFBP7112P_RS11430	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS11480	COG3318	Belongs to the UPF0149 family
XcvCFBP7112P_RS11480	COG3012	SEC-C Motif Domain Protein
XcvCFBP7112P_RS11500	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XcvCFBP7112P_RS11620	COG2133	pyrroloquinoline quinone binding
XcvCFBP7112P_RS11625	COG1408	metallophosphoesterase
XcvCFBP7112P_RS11630	COG0300	oxidoreductase activity
XcvCFBP7112P_RS11635	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS11645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7112P_RS11650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7112P_RS11665	COG0300	oxidoreductase activity
XcvCFBP7112P_RS11670	COG2814	Major facilitator Superfamily
XcvCFBP7112P_RS11680	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS11690	COG4221	oxidoreductase activity
XcvCFBP7112P_RS11695	COG0300	oxidoreductase activity
XcvCFBP7112P_RS11725	COG1136	(ABC) transporter
XcvCFBP7112P_RS11730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XcvCFBP7112P_RS11735	COG3321	synthase
XcvCFBP7112P_RS11735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcvCFBP7112P_RS11735	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS11735	COG4221	oxidoreductase activity
XcvCFBP7112P_RS11770	COG3220	belongs to the UPF0276 family
XcvCFBP7112P_RS11790	COG3920	Histidine kinase
XcvCFBP7112P_RS11800	COG1238	metal cluster binding
XcvCFBP7112P_RS11830	COG3279	Response regulator of the LytR AlgR family
XcvCFBP7112P_RS11835	COG3275	phosphorelay sensor kinase activity
XcvCFBP7112P_RS11875	COG4566	intracellular signal transduction
XcvCFBP7112P_RS11885	COG5001	Diguanylate cyclase
XcvCFBP7112P_RS11905	COG3685	Protein conserved in bacteria
XcvCFBP7112P_RS11925	COG0243	molybdopterin cofactor binding
XcvCFBP7112P_RS11930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcvCFBP7112P_RS11930	COG1648	precorrin-2 dehydrogenase activity
XcvCFBP7112P_RS11945	COG2814	Major facilitator Superfamily
XcvCFBP7112P_RS11960	COG1335	isochorismatase
XcvCFBP7112P_RS11975	COG2197	response regulator
XcvCFBP7112P_RS11990	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS11995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcvCFBP7112P_RS12000	COG3002	Belongs to the UPF0753 family
XcvCFBP7112P_RS12005	COG0519	Catalyzes the synthesis of GMP from XMP
XcvCFBP7112P_RS12005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcvCFBP7112P_RS12015	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XcvCFBP7112P_RS12025	COG0475	glutathione-regulated potassium exporter activity
XcvCFBP7112P_RS12025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcvCFBP7112P_RS12030	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XcvCFBP7112P_RS12040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcvCFBP7112P_RS12045	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XcvCFBP7112P_RS12055	COG0776	regulation of translation
XcvCFBP7112P_RS12060	COG0539	negative regulation of cytoplasmic translation
XcvCFBP7112P_RS12065	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XcvCFBP7112P_RS12080	COG2957	Belongs to the agmatine deiminase family
XcvCFBP7112P_RS12085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcvCFBP7112P_RS12110	COG0395	ABC-type sugar transport system, permease component
XcvCFBP7112P_RS12115	COG1175	transmembrane transport
XcvCFBP7112P_RS12145	COG2350	Protein conserved in bacteria
XcvCFBP7112P_RS12150	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XcvCFBP7112P_RS12155	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XcvCFBP7112P_RS12160	COG1187	pseudouridine synthase activity
XcvCFBP7112P_RS12180	COG0436	Aminotransferase
XcvCFBP7112P_RS12185	COG4133	protoheme IX ABC transporter activity
XcvCFBP7112P_RS12205	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcvCFBP7112P_RS12210	COG1138	Cytochrome C-type biogenesis protein
XcvCFBP7112P_RS12230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcvCFBP7112P_RS12235	COG1278	Cold shock
XcvCFBP7112P_RS12240	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XcvCFBP7112P_RS12245	COG4988	ABC transporter
XcvCFBP7112P_RS12255	COG1294	oxidase, subunit
XcvCFBP7112P_RS12285	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XcvCFBP7112P_RS12290	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XcvCFBP7112P_RS12300	COG0165	Argininosuccinate lyase
XcvCFBP7112P_RS12305	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XcvCFBP7112P_RS12315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XcvCFBP7112P_RS12320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcvCFBP7112P_RS12330	COG0137	argininosuccinate synthase activity
XcvCFBP7112P_RS12335	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XcvCFBP7112P_RS12345	COG0215	cysteine-tRNA ligase activity
XcvCFBP7112P_RS12350	COG2166	iron-sulfur cluster assembly
XcvCFBP7112P_RS12365	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XcvCFBP7112P_RS12370	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XcvCFBP7112P_RS12390	COG4302	ethanolamine ammonia-lyase activity
XcvCFBP7112P_RS12440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XcvCFBP7112P_RS12445	COG0402	S-adenosylhomocysteine deaminase activity
XcvCFBP7112P_RS12455	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcvCFBP7112P_RS12460	COG1509	lysine 2,3-aminomutase activity
XcvCFBP7112P_RS12465	COG5001	Diguanylate cyclase
XcvCFBP7112P_RS12465	COG3300	MHYT domain
XcvCFBP7112P_RS12480	COG0483	inositol monophosphate 1-phosphatase activity
XcvCFBP7112P_RS12485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XcvCFBP7112P_RS12505	COG0488	(ABC) transporter
XcvCFBP7112P_RS12510	COG0513	Belongs to the DEAD box helicase family
XcvCFBP7112P_RS12515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XcvCFBP7112P_RS12520	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XcvCFBP7112P_RS12530	COG0625	glutathione transferase activity
XcvCFBP7112P_RS12540	COG4681	YaeQ
XcvCFBP7112P_RS12545	COG2081	HI0933 family
XcvCFBP7112P_RS12555	COG0501	Belongs to the peptidase M48B family
XcvCFBP7112P_RS12560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcvCFBP7112P_RS12565	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS12590	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XcvCFBP7112P_RS12595	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcvCFBP7112P_RS12600	COG0802	atpase or kinase
XcvCFBP7112P_RS12605	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcvCFBP7112P_RS12605	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XcvCFBP7112P_RS12610	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcvCFBP7112P_RS12615	COG1570	exodeoxyribonuclease VII activity
XcvCFBP7112P_RS12625	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcvCFBP7112P_RS12670	COG0835	chemotaxis
XcvCFBP7112P_RS12675	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS12680	COG2094	Belongs to the DNA glycosylase MPG family
XcvCFBP7112P_RS12685	COG1201	RNA secondary structure unwinding
XcvCFBP7112P_RS12705	COG2969	positive regulation of protein catabolic process
XcvCFBP7112P_RS12710	COG0625	glutathione transferase activity
XcvCFBP7112P_RS12715	COG2857	Cytochrome c1
XcvCFBP7112P_RS12720	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XcvCFBP7112P_RS12725	COG0723	plastoquinol--plastocyanin reductase activity
XcvCFBP7112P_RS12735	COG0741	lytic transglycosylase activity
XcvCFBP7112P_RS12750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcvCFBP7112P_RS12755	COG1702	phosphate starvation-inducible protein PhoH
XcvCFBP7112P_RS12765	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XcvCFBP7112P_RS12775	COG4535	Mg2 and Co2 transporter CorC
XcvCFBP7112P_RS12790	COG1012	belongs to the aldehyde dehydrogenase family
XcvCFBP7112P_RS12795	COG1177	transmembrane transport
XcvCFBP7112P_RS12800	COG1176	ABC-type spermidine putrescine transport system, permease component I
XcvCFBP7112P_RS12810	COG3842	ATPase activity
XcvCFBP7112P_RS12830	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XcvCFBP7112P_RS12845	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XcvCFBP7112P_RS12850	COG0174	glutamine synthetase
XcvCFBP7112P_RS12855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcvCFBP7112P_RS12865	COG2703	oxygen carrier activity
XcvCFBP7112P_RS12870	COG0477	Major facilitator Superfamily
XcvCFBP7112P_RS12880	COG0243	molybdopterin cofactor binding
XcvCFBP7112P_RS12885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XcvCFBP7112P_RS12890	COG2223	nitrite transmembrane transporter activity
XcvCFBP7112P_RS12905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XcvCFBP7112P_RS12915	COG2733	membrane
XcvCFBP7112P_RS12920	COG0784	Response regulator, receiver
XcvCFBP7112P_RS12920	COG5002	protein histidine kinase activity
XcvCFBP7112P_RS12920	COG2205	protein histidine kinase activity
XcvCFBP7112P_RS12940	COG0477	Major facilitator Superfamily
XcvCFBP7112P_RS12945	COG2902	Dehydrogenase
XcvCFBP7112P_RS12955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7112P_RS12960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7112P_RS12965	COG1609	Transcriptional regulator
XcvCFBP7112P_RS12970	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcvCFBP7112P_RS12970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcvCFBP7112P_RS12975	COG1105	Belongs to the carbohydrate kinase PfkB family
XcvCFBP7112P_RS12980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcvCFBP7112P_RS12980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcvCFBP7112P_RS13000	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XcvCFBP7112P_RS13010	COG1862	Preprotein translocase
XcvCFBP7112P_RS13015	COG0343	queuine tRNA-ribosyltransferase activity
XcvCFBP7112P_RS13020	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XcvCFBP7112P_RS13055	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XcvCFBP7112P_RS13060	COG3291	Pkd domain containing protein
XcvCFBP7112P_RS13065	COG0405	Gamma-glutamyltransferase
XcvCFBP7112P_RS13070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XcvCFBP7112P_RS13085	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XcvCFBP7112P_RS13090	COG0742	ribosomal rna small subunit methyltransferase
XcvCFBP7112P_RS13095	COG0326	Molecular chaperone. Has ATPase activity
XcvCFBP7112P_RS13185	COG0531	amino acid
XcvCFBP7112P_RS13200	COG0006	proline dipeptidase activity
XcvCFBP7112P_RS13210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcvCFBP7112P_RS13225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcvCFBP7112P_RS13230	COG3938	Belongs to the proline racemase family
XcvCFBP7112P_RS13240	COG0552	protein localization to endoplasmic reticulum
XcvCFBP7112P_RS13245	COG1194	a g-specific adenine glycosylase
XcvCFBP7112P_RS13250	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XcvCFBP7112P_RS13255	COG4191	Histidine kinase
XcvCFBP7112P_RS13255	COG0784	Response regulator, receiver
XcvCFBP7112P_RS13270	COG0322	excinuclease ABC activity
XcvCFBP7112P_RS13285	COG3040	lipid binding
XcvCFBP7112P_RS13295	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7112P_RS13305	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XcvCFBP7112P_RS13325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcvCFBP7112P_RS13330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcvCFBP7112P_RS13335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcvCFBP7112P_RS13360	COG0438	transferase activity, transferring glycosyl groups
XcvCFBP7112P_RS13370	COG0438	transferase activity, transferring glycosyl groups
XcvCFBP7112P_RS13375	COG0438	transferase activity, transferring glycosyl groups
XcvCFBP7112P_RS13425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcvCFBP7112P_RS13425	COG0072	phenylalanine-tRNA ligase activity
XcvCFBP7112P_RS13430	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XcvCFBP7112P_RS13445	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XcvCFBP7112P_RS13450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XcvCFBP7112P_RS13475	COG1082	Xylose isomerase domain protein TIM barrel
XcvCFBP7112P_RS13525	COG3702	type iv secretory pathway
XcvCFBP7112P_RS13545	COG2948	multi-organism process
XcvCFBP7112P_RS13565	COG3505	Type IV secretory pathway VirD4
XcvCFBP7112P_RS13580	COG0556	nucleotide-excision repair
XcvCFBP7112P_RS13645	COG3275	phosphorelay sensor kinase activity
XcvCFBP7112P_RS13650	COG1611	Belongs to the LOG family
XcvCFBP7112P_RS13665	COG2095	MarC family integral membrane protein
XcvCFBP7112P_RS13675	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcvCFBP7112P_RS13710	COG1185	polyribonucleotide nucleotidyltransferase activity
XcvCFBP7112P_RS13715	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XcvCFBP7112P_RS13720	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XcvCFBP7112P_RS13725	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XcvCFBP7112P_RS13730	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XcvCFBP7112P_RS13735	COG0195	Participates in both transcription termination and antitermination
XcvCFBP7112P_RS13740	COG0779	Required for maturation of 30S ribosomal subunits
XcvCFBP7112P_RS13750	COG1007	ATP synthesis coupled electron transport
XcvCFBP7112P_RS13775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcvCFBP7112P_RS13780	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XcvCFBP7112P_RS13790	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XcvCFBP7112P_RS13795	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XcvCFBP7112P_RS13800	COG0649	NAD binding
XcvCFBP7112P_RS13805	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcvCFBP7112P_RS13810	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcvCFBP7112P_RS13815	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcvCFBP7112P_RS13830	COG0149	triose-phosphate isomerase activity
XcvCFBP7112P_RS13835	COG0300	oxidoreductase activity
XcvCFBP7112P_RS13865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcvCFBP7112P_RS13870	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XcvCFBP7112P_RS13875	COG0159	tryptophan synthase activity
XcvCFBP7112P_RS13885	COG0133	tryptophan synthase activity
XcvCFBP7112P_RS13895	COG0135	phosphoribosylanthranilate isomerase activity
XcvCFBP7112P_RS13900	COG0101	tRNA pseudouridine synthase activity
XcvCFBP7112P_RS13915	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XcvCFBP7112P_RS13920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XcvCFBP7112P_RS13925	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XcvCFBP7112P_RS13930	COG2890	protein-(glutamine-N5) methyltransferase activity
XcvCFBP7112P_RS13940	COG0688	phosphatidylethanolamine metabolic process
XcvCFBP7112P_RS13955	COG0433	COG0433 Predicted ATPase
XcvCFBP7112P_RS13960	COG0494	nUDIX hydrolase
XcvCFBP7112P_RS13980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcvCFBP7112P_RS13985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcvCFBP7112P_RS14010	COG0717	Belongs to the dCTP deaminase family
XcvCFBP7112P_RS14020	COG0489	protein tyrosine kinase activity
XcvCFBP7112P_RS14040	COG3590	peptidase
XcvCFBP7112P_RS14045	COG3590	peptidase
XcvCFBP7112P_RS14065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcvCFBP7112P_RS14070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcvCFBP7112P_RS14075	COG2311	Membrane
XcvCFBP7112P_RS14080	COG1047	Peptidyl-prolyl cis-trans
XcvCFBP7112P_RS14085	COG0791	NLP P60 protein
XcvCFBP7112P_RS14090	COG0791	NLP P60 protein
XcvCFBP7112P_RS14100	COG4106	trans-aconitate 2-methyltransferase activity
XcvCFBP7112P_RS14105	COG1301	dicarboxylic acid transport
XcvCFBP7112P_RS14110	COG1785	Belongs to the alkaline phosphatase family
XcvCFBP7112P_RS14120	COG0037	tRNA processing
XcvCFBP7112P_RS14125	COG1722	exodeoxyribonuclease VII activity
XcvCFBP7112P_RS14130	COG0142	geranyltranstransferase activity
XcvCFBP7112P_RS14145	COG0312	modulator of DNA gyrase
XcvCFBP7112P_RS14150	COG3028	Belongs to the UPF0307 family
XcvCFBP7112P_RS14155	COG0312	modulator of DNA gyrase
XcvCFBP7112P_RS14165	COG3164	Protein of unknown function
XcvCFBP7112P_RS14175	COG0424	maF-like protein
XcvCFBP7112P_RS14180	COG2968	Membrane
XcvCFBP7112P_RS14195	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XcvCFBP7112P_RS14210	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XcvCFBP7112P_RS14225	COG0495	leucyl-tRNA aminoacylation
XcvCFBP7112P_RS14235	COG3118	belongs to the thioredoxin family
XcvCFBP7112P_RS14270	COG2155	Conserved Protein
XcvCFBP7112P_RS14315	COG1132	(ABC) transporter
XcvCFBP7112P_RS14340	COG1538	Outer membrane efflux protein
XcvCFBP7112P_RS14345	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_RS14350	COG5000	phosphorelay sensor kinase activity
XcvCFBP7112P_RS14350	COG5002	protein histidine kinase activity
XcvCFBP7112P_RS14355	COG0475	glutathione-regulated potassium exporter activity
XcvCFBP7112P_RS14365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcvCFBP7112P_RS14390	COG1187	pseudouridine synthase activity
XcvCFBP7112P_RS14395	COG5002	protein histidine kinase activity
XcvCFBP7112P_RS14395	COG5001	Diguanylate cyclase
XcvCFBP7112P_RS14405	COG1595	DNA-templated transcription, initiation
XcvCFBP7112P_RS14515	COG0667	Aldo Keto reductase
XcvCFBP7112P_RS14525	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS14535	COG2207	Transcriptional regulator
XcvCFBP7112P_RS14545	COG1309	transcriptional regulator
XcvCFBP7112P_RS14555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7112P_RS14570	COG0735	belongs to the Fur family
XcvCFBP7112P_RS14575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcvCFBP7112P_RS14600	COG4452	Inner membrane protein CreD
XcvCFBP7112P_RS14610	COG2205	protein histidine kinase activity
XcvCFBP7112P_RS14615	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_RS14620	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XcvCFBP7112P_RS14635	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XcvCFBP7112P_RS14685	COG0643	Histidine kinase
XcvCFBP7112P_RS14685	COG2198	Histidine kinase
XcvCFBP7112P_RS14690	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS14695	COG0835	chemotaxis
XcvCFBP7112P_RS14700	COG2200	EAL domain
XcvCFBP7112P_RS14700	COG2202	Pas domain
XcvCFBP7112P_RS14700	COG2199	diguanylate cyclase activity
XcvCFBP7112P_RS14705	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcvCFBP7112P_RS14710	COG2201	protein-glutamate methylesterase activity
XcvCFBP7112P_RS14715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcvCFBP7112P_RS14720	COG3590	peptidase
XcvCFBP7112P_RS14730	COG0588	phosphoglycerate mutase activity
XcvCFBP7112P_RS14735	COG1515	deoxyribonuclease V activity
XcvCFBP7112P_RS14745	COG1741	Belongs to the pirin family
XcvCFBP7112P_RS14760	COG1741	Belongs to the pirin family
XcvCFBP7112P_RS14765	COG1966	Carbon starvation protein
XcvCFBP7112P_RS14770	COG2879	small protein
XcvCFBP7112P_RS14820	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XcvCFBP7112P_RS14825	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcvCFBP7112P_RS14830	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcvCFBP7112P_RS14835	COG2080	2 iron, 2 sulfur cluster binding
XcvCFBP7112P_RS14840	COG0604	alcohol dehydrogenase
XcvCFBP7112P_RS14840	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS14840	COG3321	synthase
XcvCFBP7112P_RS14845	COG2203	Gaf domain
XcvCFBP7112P_RS14845	COG3706	GGDEF domain
XcvCFBP7112P_RS14845	COG4251	negative regulation of phosphorylation
XcvCFBP7112P_RS14845	COG5001	Diguanylate cyclase
XcvCFBP7112P_RS14850	COG0629	single-stranded DNA binding
XcvCFBP7112P_RS14855	COG0142	geranyltranstransferase activity
XcvCFBP7112P_RS14870	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XcvCFBP7112P_RS14885	COG0527	aspartate kinase activity
XcvCFBP7112P_RS14890	COG0384	phenazine biosynthesis protein PhzF
XcvCFBP7112P_RS14895	COG0384	phenazine biosynthesis protein PhzF
XcvCFBP7112P_RS14905	COG1764	response to oxidative stress
XcvCFBP7112P_RS14910	COG0540	Belongs to the ATCase OTCase family
XcvCFBP7112P_RS14915	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XcvCFBP7112P_RS14920	COG1678	Uncharacterized ACR, COG1678
XcvCFBP7112P_RS14930	COG0519	Catalyzes the synthesis of GMP from XMP
XcvCFBP7112P_RS14955	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XcvCFBP7112P_RS14970	COG0739	heme binding
XcvCFBP7112P_RS14990	COG0693	protein deglycase activity
XcvCFBP7112P_RS15000	COG1959	2 iron, 2 sulfur cluster binding
XcvCFBP7112P_RS15005	COG0719	Fe-S assembly protein
XcvCFBP7112P_RS15010	COG0396	ATPase activity
XcvCFBP7112P_RS15015	COG0719	Fe-S assembly protein
XcvCFBP7112P_RS15020	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XcvCFBP7112P_RS15030	COG2146	nitrite reductase [NAD(P)H] activity
XcvCFBP7112P_RS15040	COG3128	pkhd-type hydroxylase
XcvCFBP7112P_RS15065	COG1477	protein flavinylation
XcvCFBP7112P_RS15070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcvCFBP7112P_RS15080	COG1555	photosystem II stabilization
XcvCFBP7112P_RS15095	COG3178	'Phosphotransferase
XcvCFBP7112P_RS15100	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XcvCFBP7112P_RS15115	COG0628	permease
XcvCFBP7112P_RS15125	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XcvCFBP7112P_RS15135	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XcvCFBP7112P_RS15155	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XcvCFBP7112P_RS15160	COG0271	Belongs to the BolA IbaG family
XcvCFBP7112P_RS15170	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XcvCFBP7112P_RS15180	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XcvCFBP7112P_RS15185	COG1137	ATPase activity
XcvCFBP7112P_RS15200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcvCFBP7112P_RS15205	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XcvCFBP7112P_RS15210	COG1660	Displays ATPase and GTPase activities
XcvCFBP7112P_RS15220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcvCFBP7112P_RS15225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcvCFBP7112P_RS15230	COG2239	Acts as a magnesium transporter
XcvCFBP7112P_RS15240	COG1294	oxidase, subunit
XcvCFBP7112P_RS15245	COG1271	oxidase subunit
XcvCFBP7112P_RS15255	COG1113	amino acid transport
XcvCFBP7112P_RS15285	COG2197	response regulator
XcvCFBP7112P_RS15290	COG0531	amino acid
XcvCFBP7112P_RS15385	COG2814	Major facilitator Superfamily
XcvCFBP7112P_RS15400	COG0754	glutathionylspermidine amidase activity
XcvCFBP7112P_RS15425	COG1842	Phage shock protein A
XcvCFBP7112P_RS15435	COG0259	pyridoxamine-phosphate oxidase activity
XcvCFBP7112P_RS15440	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XcvCFBP7112P_RS15445	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XcvCFBP7112P_RS15455	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XcvCFBP7112P_RS15460	COG2814	Major facilitator Superfamily
XcvCFBP7112P_RS15480	COG0784	Response regulator, receiver
XcvCFBP7112P_RS15480	COG2205	protein histidine kinase activity
XcvCFBP7112P_RS15480	COG2198	Histidine kinase
XcvCFBP7112P_RS15485	COG2353	YceI-like domain
XcvCFBP7112P_RS15505	COG1760	l-serine dehydratase
XcvCFBP7112P_RS15520	COG0460	homoserine dehydrogenase
XcvCFBP7112P_RS15520	COG0527	aspartate kinase activity
XcvCFBP7112P_RS15525	COG0626	cystathionine gamma-synthase activity
XcvCFBP7112P_RS15530	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcvCFBP7112P_RS15535	COG0739	heme binding
XcvCFBP7112P_RS15540	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XcvCFBP7112P_RS15545	COG1272	protein, Hemolysin III
XcvCFBP7112P_RS15550	COG2982	Protein involved in outer membrane biogenesis
XcvCFBP7112P_RS15555	COG0516	GMP reductase activity
XcvCFBP7112P_RS15555	COG0517	IMP dehydrogenase activity
XcvCFBP7112P_RS15560	COG0463	Glycosyl transferase, family 2
XcvCFBP7112P_RS15565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcvCFBP7112P_RS15570	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XcvCFBP7112P_RS15580	COG4771	TonB-dependent receptor
XcvCFBP7112P_RS15590	COG1309	transcriptional regulator
XcvCFBP7112P_RS15600	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7112P_RS15630	COG0509	glycine decarboxylation via glycine cleavage system
XcvCFBP7112P_RS15635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XcvCFBP7112P_RS15650	COG1742	UPF0060 membrane protein
XcvCFBP7112P_RS15655	COG3956	TIGRFAM MazG family protein
XcvCFBP7112P_RS15660	COG1218	3'(2'),5'-bisphosphate nucleotidase
XcvCFBP7112P_RS15665	COG0494	nUDIX hydrolase
XcvCFBP7112P_RS15675	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XcvCFBP7112P_RS15680	COG0837	glucose binding
XcvCFBP7112P_RS15695	COG3858	chitin binding
XcvCFBP7112P_RS15695	COG1388	LysM domain
XcvCFBP7112P_RS15710	COG1472	Belongs to the glycosyl hydrolase 3 family
XcvCFBP7112P_RS15725	COG0531	amino acid
XcvCFBP7112P_RS15735	COG1486	melibiose metabolic process
XcvCFBP7112P_RS15745	COG3537	Alpha-1,2-mannosidase
XcvCFBP7112P_RS15785	COG3142	Participates in the control of copper homeostasis
XcvCFBP7112P_RS15790	COG1446	asparaginase
XcvCFBP7112P_RS15815	COG0643	Histidine kinase
XcvCFBP7112P_RS15815	COG0784	Response regulator, receiver
XcvCFBP7112P_RS15815	COG2198	Histidine kinase
XcvCFBP7112P_RS15820	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS15825	COG0835	chemotaxis
XcvCFBP7112P_RS15840	COG0189	ligase activity
XcvCFBP7112P_RS15850	COG1397	ADP-ribosylglycohydrolase
XcvCFBP7112P_RS15860	COG1199	ATP-dependent helicase activity
XcvCFBP7112P_RS15870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcvCFBP7112P_RS15875	COG1215	transferase activity, transferring glycosyl groups
XcvCFBP7112P_RS15890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcvCFBP7112P_RS15900	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XcvCFBP7112P_RS15905	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XcvCFBP7112P_RS15910	COG0535	radical SAM domain protein
XcvCFBP7112P_RS15915	COG0535	radical SAM domain protein
XcvCFBP7112P_RS15930	COG0837	glucose binding
XcvCFBP7112P_RS15945	COG1643	Atp-dependent helicase
XcvCFBP7112P_RS15950	COG0783	Belongs to the Dps family
XcvCFBP7112P_RS15955	COG0514	ATP-dependent DNA helicase (RecQ)
XcvCFBP7112P_RS16000	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS16020	COG3920	Histidine kinase
XcvCFBP7112P_RS16025	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XcvCFBP7112P_RS16035	COG0602	queuosine metabolic process
XcvCFBP7112P_RS16045	COG2885	chlorophyll binding
XcvCFBP7112P_RS16050	COG0823	Involved in the tonB-independent uptake of proteins
XcvCFBP7112P_RS16060	COG0848	biopolymer transport protein
XcvCFBP7112P_RS16070	COG0824	Thioesterase
XcvCFBP7112P_RS16075	COG2255	four-way junction helicase activity
XcvCFBP7112P_RS16080	COG3158	transport of potassium into the cell
XcvCFBP7112P_RS16085	COG0632	four-way junction helicase activity
XcvCFBP7112P_RS16090	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XcvCFBP7112P_RS16095	COG0217	transcriptional regulatory protein
XcvCFBP7112P_RS16110	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XcvCFBP7112P_RS16125	COG0477	Major facilitator Superfamily
XcvCFBP7112P_RS16165	COG0488	(ABC) transporter
XcvCFBP7112P_RS16205	COG4651	solute:proton antiporter activity
XcvCFBP7112P_RS16205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcvCFBP7112P_RS16215	COG4772	TonB-dependent receptor
XcvCFBP7112P_RS16225	COG4264	IucA IucC family
XcvCFBP7112P_RS16240	COG0019	diaminopimelate decarboxylase activity
XcvCFBP7112P_RS16265	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XcvCFBP7112P_RS16275	COG1492	cobalamin metabolic process
XcvCFBP7112P_RS16285	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcvCFBP7112P_RS16310	COG4206	TonB-dependent receptor
XcvCFBP7112P_RS16315	COG0542	response to heat
XcvCFBP7112P_RS16320	COG1116	anion transmembrane transporter activity
XcvCFBP7112P_RS16325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcvCFBP7112P_RS16330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XcvCFBP7112P_RS16335	COG0667	Aldo Keto reductase
XcvCFBP7112P_RS16340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcvCFBP7112P_RS16345	COG4771	TonB-dependent receptor
XcvCFBP7112P_RS16350	COG2827	Endonuclease containing a URI domain
XcvCFBP7112P_RS16390	COG1877	trehalose-phosphatase activity
XcvCFBP7112P_RS16395	COG3387	PFAM Glycoside hydrolase 15-related
XcvCFBP7112P_RS16415	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS16420	COG3011	Protein conserved in bacteria
XcvCFBP7112P_RS16435	COG0564	pseudouridine synthase activity
XcvCFBP7112P_RS16440	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcvCFBP7112P_RS16450	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XcvCFBP7112P_RS16450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcvCFBP7112P_RS16465	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XcvCFBP7112P_RS16470	COG0045	succinate-CoA ligase (ADP-forming) activity
XcvCFBP7112P_RS16510	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XcvCFBP7112P_RS16515	COG0237	dephospho-CoA kinase activity
XcvCFBP7112P_RS16525	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_RS16535	COG0189	ligase activity
XcvCFBP7112P_RS16595	COG3209	COG3209 Rhs family protein
XcvCFBP7112P_RS16640	COG2022	thiamine diphosphate biosynthetic process
XcvCFBP7112P_RS16645	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XcvCFBP7112P_RS16650	COG0471	metal ion transport
XcvCFBP7112P_RS16650	COG3273	potassium ion transport
XcvCFBP7112P_RS16675	COG1970	mechanosensitive ion channel activity
XcvCFBP7112P_RS16685	COG1609	Transcriptional regulator
XcvCFBP7112P_RS16695	COG3250	beta-galactosidase activity
XcvCFBP7112P_RS16700	COG4948	Mandelate Racemase Muconate Lactonizing
XcvCFBP7112P_RS16710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcvCFBP7112P_RS16720	COG0308	aminopeptidase N
XcvCFBP7112P_RS16725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7112P_RS16735	COG2895	sulfate adenylyltransferase (ATP) activity
XcvCFBP7112P_RS16735	COG0529	Catalyzes the synthesis of activated sulfate
XcvCFBP7112P_RS16740	COG0175	sulfate reduction
XcvCFBP7112P_RS16745	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcvCFBP7112P_RS16750	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XcvCFBP7112P_RS16755	COG0175	sulfate reduction
XcvCFBP7112P_RS16775	COG2205	protein histidine kinase activity
XcvCFBP7112P_RS16775	COG2198	Histidine kinase
XcvCFBP7112P_RS16775	COG0784	Response regulator, receiver
XcvCFBP7112P_RS16795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcvCFBP7112P_RS16795	COG1648	precorrin-2 dehydrogenase activity
XcvCFBP7112P_RS16810	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XcvCFBP7112P_RS16815	COG3588	fructose-bisphosphate aldolase
XcvCFBP7112P_RS16830	COG0469	pyruvate kinase activity
XcvCFBP7112P_RS16840	COG0126	phosphoglycerate kinase activity
XcvCFBP7112P_RS16865	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XcvCFBP7112P_RS16875	COG3047	cAMP biosynthetic process
XcvCFBP7112P_RS16880	COG3047	cAMP biosynthetic process
XcvCFBP7112P_RS16890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcvCFBP7112P_RS16890	COG3453	Protein conserved in bacteria
XcvCFBP7112P_RS16895	COG0725	ABC transporter, periplasmic molybdate-binding protein
XcvCFBP7112P_RS16900	COG4149	molybdate abc transporter
XcvCFBP7112P_RS16905	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XcvCFBP7112P_RS16940	COG1376	ErfK ybiS ycfS ynhG family protein
XcvCFBP7112P_RS16945	COG0739	heme binding
XcvCFBP7112P_RS16950	COG4773	Receptor
XcvCFBP7112P_RS16955	COG0596	Alpha beta hydrolase
XcvCFBP7112P_RS16960	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XcvCFBP7112P_RS16965	COG1301	dicarboxylic acid transport
XcvCFBP7112P_RS16975	COG2304	oxidoreductase activity
XcvCFBP7112P_RS16995	COG0714	Associated with various cellular activities
XcvCFBP7112P_RS17025	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XcvCFBP7112P_RS17050	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XcvCFBP7112P_RS17060	COG2721	sulfolactate sulfo-lyase activity
XcvCFBP7112P_RS17075	COG2271	Major facilitator Superfamily
XcvCFBP7112P_RS17090	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS17095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcvCFBP7112P_RS17110	COG1561	YicC-like family, N-terminal region
XcvCFBP7112P_RS17115	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XcvCFBP7112P_RS17125	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XcvCFBP7112P_RS17130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XcvCFBP7112P_RS17145	COG0006	proline dipeptidase activity
XcvCFBP7112P_RS17155	COG0006	proline dipeptidase activity
XcvCFBP7112P_RS17160	COG3079	Belongs to the UPF0149 family
XcvCFBP7112P_RS17180	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XcvCFBP7112P_RS17190	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XcvCFBP7112P_RS17200	COG2912	Transglutaminase-like superfamily
XcvCFBP7112P_RS17205	COG1773	rubredoxin
XcvCFBP7112P_RS17210	COG0352	thiamine-phosphate diphosphorylase activity
XcvCFBP7112P_RS17230	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcvCFBP7112P_RS17245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcvCFBP7112P_RS17275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XcvCFBP7112P_RS17280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcvCFBP7112P_RS17295	COG0671	phosphoesterase, PA-phosphatase related
XcvCFBP7112P_RS17300	COG3781	membrane
XcvCFBP7112P_RS17310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcvCFBP7112P_RS17315	COG0563	adenylate kinase activity
XcvCFBP7112P_RS17330	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XcvCFBP7112P_RS17340	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XcvCFBP7112P_RS17360	COG3710	Transcriptional regulator
XcvCFBP7112P_RS17365	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XcvCFBP7112P_RS17380	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS17385	COG0405	Gamma-glutamyltransferase
XcvCFBP7112P_RS17390	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XcvCFBP7112P_RS17410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XcvCFBP7112P_RS17415	COG0473	3-isopropylmalate dehydrogenase activity
XcvCFBP7112P_RS17420	COG0066	3-isopropylmalate dehydratase activity
XcvCFBP7112P_RS17425	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XcvCFBP7112P_RS17445	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcvCFBP7112P_RS17450	COG1538	Outer membrane efflux protein
XcvCFBP7112P_RS17455	COG1519	Transferase
XcvCFBP7112P_RS17465	COG1560	Kdo2-lipid A biosynthetic process
XcvCFBP7112P_RS17520	COG0280	phosphate acetyltransferase
XcvCFBP7112P_RS17520	COG0281	malic enzyme
XcvCFBP7112P_RS17525	COG1301	dicarboxylic acid transport
XcvCFBP7112P_RS17550	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS17560	COG0667	Aldo Keto reductase
XcvCFBP7112P_RS17575	COG2197	response regulator
XcvCFBP7112P_RS17590	COG0642	Histidine kinase
XcvCFBP7112P_RS17610	COG2851	Citrate transporter
XcvCFBP7112P_RS17615	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS17620	COG1609	Transcriptional regulator
XcvCFBP7112P_RS17625	COG2211	Major facilitator Superfamily
XcvCFBP7112P_RS17655	COG1162	GTPase activity
XcvCFBP7112P_RS17660	COG0436	Aminotransferase
XcvCFBP7112P_RS17675	COG0726	polysaccharide deacetylase
XcvCFBP7112P_RS17680	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcvCFBP7112P_RS17695	COG3964	amidohydrolase
XcvCFBP7112P_RS17700	COG0402	S-adenosylhomocysteine deaminase activity
XcvCFBP7112P_RS17725	COG1307	EDD domain protein, DegV family
XcvCFBP7112P_RS17730	COG0242	peptide deformylase activity
XcvCFBP7112P_RS17755	COG0457	Tetratricopeptide repeat
XcvCFBP7112P_RS17760	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XcvCFBP7112P_RS17765	COG1215	transferase activity, transferring glycosyl groups
XcvCFBP7112P_RS17770	COG1215	transferase activity, transferring glycosyl groups
XcvCFBP7112P_RS17785	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XcvCFBP7112P_RS17840	COG2188	Transcriptional regulator
XcvCFBP7112P_RS17850	COG1450	Type ii and iii secretion system protein
XcvCFBP7112P_RS17865	COG3166	PFAM Fimbrial assembly family protein
XcvCFBP7112P_RS17870	COG3156	type II secretion system protein K
XcvCFBP7112P_RS17875	COG4795	General secretion pathway protein
XcvCFBP7112P_RS17880	COG2165	general secretion pathway protein
XcvCFBP7112P_RS17885	COG4970	Tfp pilus assembly protein FimT
XcvCFBP7112P_RS17890	COG2165	general secretion pathway protein
XcvCFBP7112P_RS17895	COG1459	type II secretion system
XcvCFBP7112P_RS17905	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcvCFBP7112P_RS17910	COG1404	Belongs to the peptidase S8 family
XcvCFBP7112P_RS17915	COG5295	Hep Hag repeat protein
XcvCFBP7112P_RS17920	COG1404	Belongs to the peptidase S8 family
XcvCFBP7112P_RS17925	COG5295	Hep Hag repeat protein
XcvCFBP7112P_RS17930	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XcvCFBP7112P_RS17930	COG0047	phosphoribosylformylglycinamidine synthase activity
XcvCFBP7112P_RS17945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcvCFBP7112P_RS17960	COG4974	Belongs to the 'phage' integrase family
XcvCFBP7112P_RS17975	COG0795	lipopolysaccharide-transporting ATPase activity
XcvCFBP7112P_RS17985	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcvCFBP7112P_RS18000	COG0525	valine-tRNA ligase activity
XcvCFBP7112P_RS18035	COG1183	phosphatidylcholine synthase activity
XcvCFBP7112P_RS18045	COG0442	prolyl-tRNA aminoacylation
XcvCFBP7112P_RS18060	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcvCFBP7112P_RS18065	COG1127	ABC transporter
XcvCFBP7112P_RS18070	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcvCFBP7112P_RS18070	COG3218	ABC-type transport auxiliary lipoprotein component
XcvCFBP7112P_RS18100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcvCFBP7112P_RS18105	COG0662	Cupin 2, conserved barrel domain protein
XcvCFBP7112P_RS18105	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XcvCFBP7112P_RS18135	COG2086	electron transfer activity
XcvCFBP7112P_RS18150	COG2226	methyltransferase
XcvCFBP7112P_RS18155	COG0463	Glycosyl transferase, family 2
XcvCFBP7112P_RS18165	COG0463	Glycosyl transferase, family 2
XcvCFBP7112P_RS18180	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XcvCFBP7112P_RS18205	COG0626	cystathionine gamma-synthase activity
XcvCFBP7112P_RS18235	COG0625	glutathione transferase activity
XcvCFBP7112P_RS18250	COG0513	Belongs to the DEAD box helicase family
XcvCFBP7112P_RS18260	COG4206	TonB-dependent receptor
XcvCFBP7112P_RS18270	COG0720	synthase
XcvCFBP7112P_RS18280	COG2015	COG2015, Alkyl sulfatase and related hydrolases
XcvCFBP7112P_RS18290	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XcvCFBP7112P_RS18295	COG1956	GAF domain-containing protein
XcvCFBP7112P_RS18305	COG2819	hydrolase of the alpha beta superfamily
XcvCFBP7112P_RS18315	COG0546	phosphoglycolate phosphatase activity
XcvCFBP7112P_RS18320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XcvCFBP7112P_RS18325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcvCFBP7112P_RS18340	COG0339	signal peptide processing
XcvCFBP7112P_RS18390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcvCFBP7112P_RS18395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7112P_RS18400	COG1136	(ABC) transporter
XcvCFBP7112P_RS18405	COG0577	efflux transmembrane transporter activity
XcvCFBP7112P_RS18410	COG1136	(ABC) transporter
XcvCFBP7112P_RS18410	COG0577	efflux transmembrane transporter activity
XcvCFBP7112P_RS18425	COG4191	Histidine kinase
XcvCFBP7112P_RS18430	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XcvCFBP7112P_RS18450	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XcvCFBP7112P_RS18455	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XcvCFBP7112P_RS18460	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XcvCFBP7112P_RS18465	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XcvCFBP7112P_RS18470	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XcvCFBP7112P_RS18475	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XcvCFBP7112P_RS18485	COG0356	it plays a direct role in the translocation of protons across the membrane
XcvCFBP7112P_RS18505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcvCFBP7112P_RS18515	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcvCFBP7112P_RS18555	COG2011	ABC-type metal ion transport system permease component
XcvCFBP7112P_RS18560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XcvCFBP7112P_RS18565	COG0697	spore germination
XcvCFBP7112P_RS18570	COG1666	GTP binding
XcvCFBP7112P_RS18600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XcvCFBP7112P_RS18605	COG1187	pseudouridine synthase activity
XcvCFBP7112P_RS18610	COG2813	Specifically methylates the guanine in position
XcvCFBP7112P_RS18630	COG2202	Pas domain
XcvCFBP7112P_RS18630	COG2205	protein histidine kinase activity
XcvCFBP7112P_RS18650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XcvCFBP7112P_RS18655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcvCFBP7112P_RS18710	COG0842	Transport permease protein
XcvCFBP7112P_RS18715	COG1131	(ABC) transporter
XcvCFBP7112P_RS18720	COG0025	NhaP-type Na H and K H
XcvCFBP7112P_RS18730	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XcvCFBP7112P_RS18735	COG1573	uracil-dna glycosylase
XcvCFBP7112P_RS18745	COG3384	dioxygenase
XcvCFBP7112P_RS18755	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS18765	COG0667	Aldo Keto reductase
XcvCFBP7112P_RS18775	COG3590	peptidase
XcvCFBP7112P_RS18790	COG0531	amino acid
XcvCFBP7112P_RS18805	COG2972	Histidine kinase
XcvCFBP7112P_RS18830	COG3685	Protein conserved in bacteria
XcvCFBP7112P_RS18835	COG3546	catalase activity
XcvCFBP7112P_RS18870	COG2204	response regulator
XcvCFBP7112P_RS18885	COG1271	oxidase subunit
XcvCFBP7112P_RS18890	COG1294	oxidase, subunit
XcvCFBP7112P_RS18905	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS18930	COG1132	(ABC) transporter
XcvCFBP7112P_RS18945	COG1063	alcohol dehydrogenase
XcvCFBP7112P_RS19020	COG0251	oxidation-reduction process
XcvCFBP7112P_RS19035	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_RS19050	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS19055	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcvCFBP7112P_RS19085	COG0659	secondary active sulfate transmembrane transporter activity
XcvCFBP7112P_RS19120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcvCFBP7112P_RS19125	COG1490	D-aminoacyl-tRNA deacylase activity
XcvCFBP7112P_RS19130	COG1560	Kdo2-lipid A biosynthetic process
XcvCFBP7112P_RS19185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XcvCFBP7112P_RS19185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcvCFBP7112P_RS19190	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XcvCFBP7112P_RS19195	COG0242	peptide deformylase activity
XcvCFBP7112P_RS19200	COG1652	LysM domain
XcvCFBP7112P_RS19205	COG0758	DNA mediated transformation
XcvCFBP7112P_RS19225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XcvCFBP7112P_RS19225	COG1754	DNA topoisomerase type I activity
XcvCFBP7112P_RS19230	COG0009	L-threonylcarbamoyladenylate synthase
XcvCFBP7112P_RS19245	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS19255	COG0616	signal peptide processing
XcvCFBP7112P_RS19260	COG0534	Mate efflux family protein
XcvCFBP7112P_RS19280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XcvCFBP7112P_RS19285	COG0625	glutathione transferase activity
XcvCFBP7112P_RS19300	COG1252	NADH dehydrogenase
XcvCFBP7112P_RS19305	COG2860	membrane
XcvCFBP7112P_RS19310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcvCFBP7112P_RS19315	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XcvCFBP7112P_RS19320	COG3437	response regulator, receiver
XcvCFBP7112P_RS19325	COG2177	Part of the ABC transporter FtsEX involved in
XcvCFBP7112P_RS19330	COG2884	Cell division ATP-binding protein ftsE
XcvCFBP7112P_RS19335	COG0513	Belongs to the DEAD box helicase family
XcvCFBP7112P_RS19340	COG3118	belongs to the thioredoxin family
XcvCFBP7112P_RS19345	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XcvCFBP7112P_RS19350	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XcvCFBP7112P_RS19355	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS19375	COG1652	LysM domain
XcvCFBP7112P_RS19380	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcvCFBP7112P_RS19380	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcvCFBP7112P_RS19385	COG1473	amidohydrolase
XcvCFBP7112P_RS19390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7112P_RS19395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7112P_RS19415	COG5383	Protein conserved in bacteria
XcvCFBP7112P_RS19455	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XcvCFBP7112P_RS19460	COG3023	N-Acetylmuramoyl-L-alanine amidase
XcvCFBP7112P_RS19470	COG4948	Mandelate Racemase Muconate Lactonizing
XcvCFBP7112P_RS19480	COG0531	amino acid
XcvCFBP7112P_RS19495	COG4682	membrane
XcvCFBP7112P_RS19500	COG2133	pyrroloquinoline quinone binding
XcvCFBP7112P_RS19510	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XcvCFBP7112P_RS19515	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XcvCFBP7112P_RS19525	COG1610	YqeY-like protein
XcvCFBP7112P_RS19535	COG1295	ribonuclease BN
XcvCFBP7112P_RS19540	COG0358	DNA primase activity
XcvCFBP7112P_RS19555	COG0109	protoheme IX farnesyltransferase activity
XcvCFBP7112P_RS19585	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XcvCFBP7112P_RS19600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XcvCFBP7112P_RS19645	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XcvCFBP7112P_RS19650	COG0739	heme binding
XcvCFBP7112P_RS19655	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XcvCFBP7112P_RS19665	COG2211	Major facilitator Superfamily
XcvCFBP7112P_RS19670	COG0708	Exodeoxyribonuclease III
XcvCFBP7112P_RS19675	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XcvCFBP7112P_RS19685	COG1192	Involved in chromosome partitioning
XcvCFBP7112P_RS19690	COG1475	DNA binding
XcvCFBP7112P_RS19710	COG0463	Glycosyl transferase, family 2
XcvCFBP7112P_RS19730	COG0756	dUTP diphosphatase activity
XcvCFBP7112P_RS19735	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XcvCFBP7112P_RS19740	COG2003	Belongs to the UPF0758 family
XcvCFBP7112P_RS19745	COG0018	arginyl-trna synthetase
XcvCFBP7112P_RS19760	COG4221	oxidoreductase activity
XcvCFBP7112P_RS19765	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XcvCFBP7112P_RS19765	COG2755	lipolytic protein G-D-S-L family
XcvCFBP7112P_RS19775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcvCFBP7112P_RS19780	COG1166	arginine decarboxylase activity
XcvCFBP7112P_RS19785	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XcvCFBP7112P_RS19805	COG3291	Pkd domain containing protein
XcvCFBP7112P_RS19805	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XcvCFBP7112P_RS19825	COG0606	chelatase, subunit chli
XcvCFBP7112P_RS19860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XcvCFBP7112P_RS19890	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XcvCFBP7112P_RS19935	COG0606	chelatase, subunit chli
XcvCFBP7112P_RS19950	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XcvCFBP7112P_RS19990	COG1690	Belongs to the RtcB family
XcvCFBP7112P_RS20025	COG1090	epimerase
XcvCFBP7112P_RS20035	COG0642	Histidine kinase
XcvCFBP7112P_RS20060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcvCFBP7112P_RS20085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XcvCFBP7112P_RS20090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcvCFBP7112P_RS20105	COG0753	catalase activity
XcvCFBP7112P_RS20120	COG2197	response regulator
XcvCFBP7112P_RS20125	COG4585	Histidine kinase
XcvCFBP7112P_RS20130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7112P_RS20135	COG1136	(ABC) transporter
XcvCFBP7112P_RS20160	COG0697	spore germination
XcvCFBP7112P_RS20180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcvCFBP7112P_RS20185	COG0180	Tryptophanyl-tRNA synthetase
XcvCFBP7112P_RS20190	COG3237	CsbD-like
XcvCFBP7112P_RS20230	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XcvCFBP7112P_RS20245	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XcvCFBP7112P_RS20250	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XcvCFBP7112P_RS20250	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XcvCFBP7112P_RS20295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcvCFBP7112P_RS20325	COG1199	ATP-dependent helicase activity
XcvCFBP7112P_RS20340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XcvCFBP7112P_RS20410	COG0625	glutathione transferase activity
XcvCFBP7112P_RS20445	COG4555	ABC transporter
XcvCFBP7112P_RS20455	COG1476	TRANSCRIPTIONal
XcvCFBP7112P_RS20475	COG1230	cation diffusion facilitator family transporter
XcvCFBP7112P_RS20485	COG4774	siderophore transport
XcvCFBP7112P_RS20500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcvCFBP7112P_RS20505	COG1131	(ABC) transporter
XcvCFBP7112P_RS20510	COG0842	Transport permease protein
XcvCFBP7112P_RS20515	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XcvCFBP7112P_RS20530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcvCFBP7112P_RS20545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcvCFBP7112P_RS20555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcvCFBP7112P_RS20570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XcvCFBP7112P_RS20570	COG1042	CoA-binding domain protein
XcvCFBP7112P_RS20570	COG0045	succinate-CoA ligase (ADP-forming) activity
XcvCFBP7112P_RS20575	COG2239	Acts as a magnesium transporter
XcvCFBP7112P_RS20595	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcvCFBP7112P_RS20600	COG3387	PFAM Glycoside hydrolase 15-related
XcvCFBP7112P_RS20615	COG3100	YcgL domain-containing protein
XcvCFBP7112P_RS20620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XcvCFBP7112P_RS20630	COG0463	Glycosyl transferase, family 2
XcvCFBP7112P_RS20640	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS20695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcvCFBP7112P_RS20710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcvCFBP7112P_RS20740	COG4946	Tricorn protease homolog
XcvCFBP7112P_RS20740	COG1506	peptidase
XcvCFBP7112P_RS20740	COG0823	Involved in the tonB-independent uptake of proteins
XcvCFBP7112P_RS20760	COG0408	coproporphyrinogen oxidase activity
XcvCFBP7112P_RS20800	COG0515	serine threonine protein kinase
XcvCFBP7112P_RS20805	COG0631	protein serine/threonine phosphatase activity
XcvCFBP7112P_RS20830	COG0667	Aldo Keto reductase
XcvCFBP7112P_RS20835	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS20875	COG1595	DNA-templated transcription, initiation
XcvCFBP7112P_RS20990	COG0210	DNA helicase
XcvCFBP7112P_RS21000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcvCFBP7112P_RS21010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcvCFBP7112P_RS21025	COG2159	amidohydrolase
XcvCFBP7112P_RS21055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7112P_RS21075	COG0357	Ribosomal RNA small subunit methyltransferase G
XcvCFBP7112P_RS21080	COG3540	Alkaline phosphatase
XcvCFBP7112P_RS21090	COG2091	lysine biosynthetic process via aminoadipic acid
XcvCFBP7112P_RS21105	COG0708	Exodeoxyribonuclease III
XcvCFBP7112P_RS21110	COG1940	carbohydrate kinase activity
XcvCFBP7112P_RS21110	COG1846	Transcriptional regulator
XcvCFBP7112P_RS21120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcvCFBP7112P_RS21135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XcvCFBP7112P_RS21140	COG3162	membrane
XcvCFBP7112P_RS21150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XcvCFBP7112P_RS21180	COG3507	Belongs to the glycosyl hydrolase 43 family
XcvCFBP7112P_RS21200	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS21205	COG0179	Fumarylacetoacetate (FAA) hydrolase
XcvCFBP7112P_RS21210	COG4948	Mandelate Racemase Muconate Lactonizing
XcvCFBP7112P_RS21215	COG3254	rhamnose metabolic process
XcvCFBP7112P_RS21220	COG0738	Major facilitator superfamily
XcvCFBP7112P_RS21225	COG1414	Transcriptional regulator
XcvCFBP7112P_RS21230	COG1971	Probably functions as a manganese efflux pump
XcvCFBP7112P_RS21235	COG2205	protein histidine kinase activity
XcvCFBP7112P_RS21250	COG3459	Glycosyltransferase 36 associated
XcvCFBP7112P_RS21255	COG2211	Major facilitator Superfamily
XcvCFBP7112P_RS21260	COG3265	gluconokinase activity
XcvCFBP7112P_RS21270	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcvCFBP7112P_RS21290	COG2911	Protein conserved in bacteria
XcvCFBP7112P_RS21295	COG0729	surface antigen
XcvCFBP7112P_RS21330	COG0752	glycyl-tRNA synthetase alpha subunit
XcvCFBP7112P_RS21335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcvCFBP7112P_RS21350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcvCFBP7112P_RS21350	COG0519	Catalyzes the synthesis of GMP from XMP
XcvCFBP7112P_RS21360	COG0805	protein transport
XcvCFBP7112P_RS21365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcvCFBP7112P_RS21370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcvCFBP7112P_RS21380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XcvCFBP7112P_RS21400	COG2974	May be involved in recombination
XcvCFBP7112P_RS21405	COG0037	tRNA processing
XcvCFBP7112P_RS21410	COG2115	Belongs to the xylose isomerase family
XcvCFBP7112P_RS21420	COG3661	Belongs to the glycosyl hydrolase 67 family
XcvCFBP7112P_RS21430	COG4948	Mandelate Racemase Muconate Lactonizing
XcvCFBP7112P_RS21440	COG1472	Belongs to the glycosyl hydrolase 3 family
XcvCFBP7112P_RS21445	COG0246	Mannitol dehydrogenase
XcvCFBP7112P_RS21495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcvCFBP7112P_RS21505	COG1070	Carbohydrate kinase
XcvCFBP7112P_RS21525	COG3386	PFAM SMP-30 Gluconolaconase
XcvCFBP7112P_RS21535	COG3250	beta-galactosidase activity
XcvCFBP7112P_RS21540	COG1904	glucuronate isomerase
XcvCFBP7112P_RS21555	COG3693	PFAM glycoside hydrolase, family 10
XcvCFBP7112P_RS21570	COG2211	Major facilitator Superfamily
XcvCFBP7112P_RS21615	COG3321	synthase
XcvCFBP7112P_RS21615	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS21615	COG0604	alcohol dehydrogenase
XcvCFBP7112P_RS21620	COG2937	Belongs to the GPAT DAPAT family
XcvCFBP7112P_RS21655	COG0284	orotidine-5'-phosphate decarboxylase activity
XcvCFBP7112P_RS21660	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XcvCFBP7112P_RS21665	COG3132	Protein of unknown function, DUF480
XcvCFBP7112P_RS21680	COG0210	DNA helicase
XcvCFBP7112P_RS21685	COG1435	thymidine kinase activity
XcvCFBP7112P_RS21695	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XcvCFBP7112P_RS21705	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XcvCFBP7112P_RS21735	COG3135	benzoate transporter
XcvCFBP7112P_RS21755	COG0676	glucose-6-phosphate 1-epimerase activity
XcvCFBP7112P_RS21765	COG3012	SEC-C Motif Domain Protein
XcvCFBP7112P_RS21770	COG0730	response to heat
XcvCFBP7112P_RS21790	COG0302	gtp cyclohydrolase
XcvCFBP7112P_RS21805	COG1566	PFAM secretion protein HlyD family protein
XcvCFBP7112P_RS21815	COG1289	transmembrane transporter activity
XcvCFBP7112P_RS21820	COG0477	Major facilitator Superfamily
XcvCFBP7112P_RS21830	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_RS21835	COG4221	oxidoreductase activity
XcvCFBP7112P_RS21845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcvCFBP7112P_RS21900	COG0564	pseudouridine synthase activity
XcvCFBP7112P_RS21945	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_RS21990	COG1074	ATP-dependent DNA helicase activity
XcvCFBP7112P_RS21995	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XcvCFBP7112P_RS22035	COG1127	ABC transporter
XcvCFBP7112P_RS22040	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcvCFBP7112P_RS22045	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcvCFBP7112P_RS22060	COG2853	Lipoprotein
XcvCFBP7112P_RS22070	COG0386	Belongs to the glutathione peroxidase family
XcvCFBP7112P_RS22080	COG1322	Protein conserved in bacteria
XcvCFBP7112P_RS22095	COG0625	glutathione transferase activity
XcvCFBP7112P_RS22105	COG0531	amino acid
XcvCFBP7112P_RS22110	COG3537	Alpha-1,2-mannosidase
XcvCFBP7112P_RS22125	COG3706	GGDEF domain
XcvCFBP7112P_RS22130	COG3835	regulator
XcvCFBP7112P_RS22135	COG1929	Belongs to the glycerate kinase type-1 family
XcvCFBP7112P_RS22140	COG2271	Major facilitator Superfamily
XcvCFBP7112P_RS22155	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcvCFBP7112P_RS22160	COG0861	Integral membrane protein TerC family
XcvCFBP7112P_RS22170	COG0584	glycerophosphoryl diester phosphodiesterase
XcvCFBP7112P_RS22185	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XcvCFBP7112P_RS22195	COG0706	membrane insertase activity
XcvCFBP7112P_RS22200	COG0594	ribonuclease P activity
XcvCFBP7112P_RS22255	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XcvCFBP7112P_RS22315	COG2951	lytic endotransglycosylase activity
XcvCFBP7112P_RS22440	COG0489	protein tyrosine kinase activity
XcvCFBP7112P_RS22615	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XcvCFBP7112P_RS22685	COG3318	Belongs to the UPF0149 family
XcvCFBP7112P_RS22685	COG3012	SEC-C Motif Domain Protein
XcvCFBP7112P_RS22705	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs