locus-tag	class	description
CLM98_RS00010	COG3135	benzoate transporter
CLM98_RS00030	COG0676	glucose-6-phosphate 1-epimerase activity
CLM98_RS00040	COG3012	SEC-C Motif Domain Protein
CLM98_RS00045	COG0730	response to heat
CLM98_RS00070	COG0302	gtp cyclohydrolase
CLM98_RS00085	COG1566	PFAM secretion protein HlyD family protein
CLM98_RS00095	COG1289	transmembrane transporter activity
CLM98_RS00100	COG0477	Major facilitator Superfamily
CLM98_RS00110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLM98_RS00130	COG4691	Plasmid stability protein
CLM98_RS00135	COG1487	ribonuclease activity
CLM98_RS00160	COG0564	pseudouridine synthase activity
CLM98_RS00195	COG0439	Biotin carboxylase
CLM98_RS00235	COG1074	ATP-dependent DNA helicase activity
CLM98_RS00240	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CLM98_RS00255	COG1127	ABC transporter
CLM98_RS00260	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CLM98_RS00265	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CLM98_RS00280	COG2853	Lipoprotein
CLM98_RS00290	COG0386	Belongs to the glutathione peroxidase family
CLM98_RS00300	COG1322	Protein conserved in bacteria
CLM98_RS00305	COG0604	alcohol dehydrogenase
CLM98_RS00325	COG0625	glutathione transferase activity
CLM98_RS00335	COG0531	amino acid
CLM98_RS00340	COG3537	Alpha-1,2-mannosidase
CLM98_RS00355	COG3706	GGDEF domain
CLM98_RS00360	COG3835	regulator
CLM98_RS00365	COG1929	Belongs to the glycerate kinase type-1 family
CLM98_RS00370	COG2271	Major facilitator Superfamily
CLM98_RS00385	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CLM98_RS00395	COG0861	Integral membrane protein TerC family
CLM98_RS00410	COG0584	glycerophosphoryl diester phosphodiesterase
CLM98_RS00425	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CLM98_RS00430	COG0726	polysaccharide deacetylase
CLM98_RS00435	COG0706	membrane insertase activity
CLM98_RS00440	COG0594	ribonuclease P activity
CLM98_RS00455	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CLM98_RS00465	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CLM98_RS00470	COG0187	DNA topoisomerase II activity
CLM98_RS00480	COG0501	Belongs to the peptidase M48B family
CLM98_RS00510	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CLM98_RS00520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLM98_RS00565	COG0793	Belongs to the peptidase S41A family
CLM98_RS00570	COG4942	peptidase
CLM98_RS00580	COG2234	aminopeptidase activity
CLM98_RS00590	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLM98_RS00600	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLM98_RS00610	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLM98_RS00620	COG1064	alcohol dehydrogenase
CLM98_RS00625	COG0493	'glutamate synthase
CLM98_RS00630	COG0070	glutamate synthase
CLM98_RS00630	COG0067	glutamate synthase
CLM98_RS00630	COG0069	glutamate synthase activity
CLM98_RS00680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CLM98_RS00695	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CLM98_RS00700	COG0297	glycogen (starch) synthase activity
CLM98_RS00700	COG0438	transferase activity, transferring glycosyl groups
CLM98_RS00720	COG0367	asparagine synthase
CLM98_RS00750	COG1132	(ABC) transporter
CLM98_RS00780	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CLM98_RS00875	COG1111	helicase
CLM98_RS00875	COG1205	dead DEAH box helicase
CLM98_RS00880	COG1272	protein, Hemolysin III
CLM98_RS00900	COG0300	oxidoreductase activity
CLM98_RS00905	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS00930	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLM98_RS00995	COG3237	CsbD-like
CLM98_RS01040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLM98_RS01050	COG0477	Major facilitator Superfamily
CLM98_RS01090	COG0714	Associated with various cellular activities
CLM98_RS01120	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CLM98_RS01130	COG4772	TonB-dependent receptor
CLM98_RS01140	COG0662	Cupin 2, conserved barrel domain protein
CLM98_RS01145	COG1012	belongs to the aldehyde dehydrogenase family
CLM98_RS01170	COG1304	FMN binding
CLM98_RS01185	COG4585	Histidine kinase
CLM98_RS01190	COG2197	response regulator
CLM98_RS01210	COG3710	Transcriptional regulator
CLM98_RS01215	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CLM98_RS01290	COG0366	Alpha amylase catalytic
CLM98_RS01295	COG0366	Alpha amylase catalytic
CLM98_RS01300	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CLM98_RS01320	COG2755	lipolytic protein G-D-S-L family
CLM98_RS01320	COG0657	acetylesterase activity
CLM98_RS01330	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CLM98_RS01345	COG3507	Belongs to the glycosyl hydrolase 43 family
CLM98_RS01350	COG1609	Transcriptional regulator
CLM98_RS01360	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CLM98_RS01365	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS01375	COG2755	lipolytic protein G-D-S-L family
CLM98_RS01390	COG3186	Phenylalanine-4-hydroxylase
CLM98_RS01395	COG1522	sequence-specific DNA binding
CLM98_RS01405	COG1752	Esterase of the alpha-beta hydrolase superfamily
CLM98_RS01415	COG1119	ATPase activity
CLM98_RS01430	COG1125	glycine betaine transport
CLM98_RS01445	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CLM98_RS01465	COG1396	sequence-specific DNA binding
CLM98_RS01490	COG0489	protein tyrosine kinase activity
CLM98_RS01495	COG2062	phosphohistidine phosphatase, SixA
CLM98_RS01505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLM98_RS01555	COG1968	undecaprenyl-diphosphatase activity
CLM98_RS01565	COG0174	glutamine synthetase
CLM98_RS01570	COG0347	Belongs to the P(II) protein family
CLM98_RS01575	COG0004	ammonium transporteR
CLM98_RS01580	COG3852	Histidine kinase
CLM98_RS01585	COG2204	response regulator
CLM98_RS01590	COG2032	superoxide dismutase activity
CLM98_RS01595	COG2032	superoxide dismutase activity
CLM98_RS01605	COG0346	lactoylglutathione lyase activity
CLM98_RS01615	COG0183	Belongs to the thiolase family
CLM98_RS01650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLM98_RS01655	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CLM98_RS01660	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CLM98_RS01675	COG0028	Belongs to the TPP enzyme family
CLM98_RS01680	COG2205	protein histidine kinase activity
CLM98_RS01705	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CLM98_RS01720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLM98_RS01730	COG0596	Alpha beta hydrolase
CLM98_RS01735	COG0727	PFAM Uncharacterised protein family (UPF0153)
CLM98_RS01740	COG0318	PFAM AMP-dependent synthetase and ligase
CLM98_RS01745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLM98_RS01760	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLM98_RS01775	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CLM98_RS01785	COG0564	pseudouridine synthase activity
CLM98_RS01810	COG0339	signal peptide processing
CLM98_RS01840	COG0475	glutathione-regulated potassium exporter activity
CLM98_RS01845	COG0583	DNA-binding transcription factor activity
CLM98_RS01850	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CLM98_RS01855	COG2224	Isocitrate lyase
CLM98_RS01885	COG4770	biotin carboxylase activity
CLM98_RS01890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CLM98_RS01895	COG1960	acyl-CoA dehydrogenase activity
CLM98_RS01955	COG0523	cobalamin synthesis protein
CLM98_RS01965	COG0697	spore germination
CLM98_RS01975	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CLM98_RS01980	COG1846	Transcriptional regulator
CLM98_RS01985	COG1764	response to oxidative stress
CLM98_RS02015	COG2130	NADP-dependent
CLM98_RS02030	COG1187	pseudouridine synthase activity
CLM98_RS02045	COG1643	Atp-dependent helicase
CLM98_RS02055	COG4807	Protein conserved in bacteria
CLM98_RS02060	COG2351	hydroxyisourate hydrolase activity
CLM98_RS02065	COG2072	flavoprotein involved in K transport
CLM98_RS02085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CLM98_RS02120	COG1957	nucleoside hydrolase
CLM98_RS02130	COG2252	PERMEase
CLM98_RS02155	COG0084	hydrolase, TatD family'
CLM98_RS02170	COG0583	DNA-binding transcription factor activity
CLM98_RS02175	COG2814	Major facilitator Superfamily
CLM98_RS02190	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CLM98_RS02195	COG1902	pentaerythritol trinitrate reductase activity
CLM98_RS02215	COG0745	RESPONSE REGULATOR receiver
CLM98_RS02220	COG2205	protein histidine kinase activity
CLM98_RS02225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM98_RS02245	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CLM98_RS02250	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CLM98_RS02255	COG0583	DNA-binding transcription factor activity
CLM98_RS02290	COG0702	epimerase
CLM98_RS02295	COG1733	regulation of RNA biosynthetic process
CLM98_RS02335	COG0129	dihydroxy-acid dehydratase activity
CLM98_RS02350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CLM98_RS02410	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CLM98_RS02415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CLM98_RS02440	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CLM98_RS02445	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CLM98_RS02455	COG3485	protocatechuate 3,4-dioxygenase
CLM98_RS02460	COG3485	protocatechuate 3,4-dioxygenase
CLM98_RS02470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CLM98_RS02475	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLM98_RS02490	COG1414	Transcriptional regulator
CLM98_RS02500	COG0657	acetylesterase activity
CLM98_RS02510	COG0445	tRNA wobble uridine modification
CLM98_RS02520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CLM98_RS02550	COG2267	carboxylic ester hydrolase activity
CLM98_RS02560	COG0156	8-amino-7-oxononanoate synthase activity
CLM98_RS02565	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CLM98_RS02570	COG1040	competence protein
CLM98_RS02575	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CLM98_RS02665	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLM98_RS02735	COG1511	domain protein
CLM98_RS02735	COG3264	Mechanosensitive ion channel
CLM98_RS02740	COG1368	sulfuric ester hydrolase activity
CLM98_RS02750	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CLM98_RS02755	COG2354	Protein conserved in bacteria
CLM98_RS02765	COG0297	glycogen (starch) synthase activity
CLM98_RS02770	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CLM98_RS02775	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CLM98_RS02800	COG0702	epimerase
CLM98_RS02810	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS02845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM98_RS02850	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS02865	COG0513	Belongs to the DEAD box helicase family
CLM98_RS02885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CLM98_RS02895	COG3483	tryptophan 2,3-dioxygenase activity
CLM98_RS02900	COG3104	oligopeptide transport
CLM98_RS02925	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CLM98_RS02945	COG1320	monovalent cation:proton antiporter activity
CLM98_RS02950	COG2212	antiporter activity
CLM98_RS02960	COG0651	ATP synthesis coupled electron transport
CLM98_RS02965	COG1006	Multisubunit Na H antiporter MnhC subunit
CLM98_RS02970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CLM98_RS02970	COG2111	Na H antiporter
CLM98_RS03000	COG3179	chitinase
CLM98_RS03020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CLM98_RS03025	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CLM98_RS03040	COG0456	acetyltransferase
CLM98_RS03045	COG1597	lipid kinase activity
CLM98_RS03080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLM98_RS03085	COG0134	indole-3-glycerol-phosphate synthase activity
CLM98_RS03095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLM98_RS03100	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CLM98_RS03110	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CLM98_RS03120	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CLM98_RS03135	COG1051	belongs to the nudix hydrolase family
CLM98_RS03175	COG0316	Belongs to the HesB IscA family
CLM98_RS03205	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CLM98_RS03225	COG2814	Major facilitator Superfamily
CLM98_RS03230	COG0583	DNA-binding transcription factor activity
CLM98_RS03235	COG2814	Major facilitator Superfamily
CLM98_RS03240	COG1289	transmembrane transporter activity
CLM98_RS03250	COG0151	Belongs to the GarS family
CLM98_RS03260	COG0138	bifunctional purine biosynthesis protein purh
CLM98_RS03265	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLM98_RS03270	COG2267	carboxylic ester hydrolase activity
CLM98_RS03275	COG0671	phosphoesterase, PA-phosphatase related
CLM98_RS03275	COG2453	phosphatase
CLM98_RS03300	COG4589	Belongs to the CDS family
CLM98_RS03305	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CLM98_RS03325	COG2264	protein methyltransferase activity
CLM98_RS03350	COG0439	Biotin carboxylase
CLM98_RS03360	COG0511	ligase activity, forming carbon-carbon bonds
CLM98_RS03365	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CLM98_RS03375	COG1324	tolerance protein
CLM98_RS03405	COG0300	oxidoreductase activity
CLM98_RS03410	COG2356	endonuclease I
CLM98_RS03425	COG0459	protein refolding
CLM98_RS03440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLM98_RS03455	COG3386	PFAM SMP-30 Gluconolaconase
CLM98_RS03465	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CLM98_RS03470	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CLM98_RS03490	COG0778	Nitroreductase
CLM98_RS03495	COG2353	YceI-like domain
CLM98_RS03525	COG3052	prosthetic group binding
CLM98_RS03550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CLM98_RS03560	COG1802	Transcriptional regulator
CLM98_RS03620	COG4221	oxidoreductase activity
CLM98_RS03635	COG4221	oxidoreductase activity
CLM98_RS03645	COG0435	Glutathione S-transferase
CLM98_RS03670	COG2409	Drug exporters of the RND superfamily
CLM98_RS03680	COG0823	Involved in the tonB-independent uptake of proteins
CLM98_RS03680	COG1506	peptidase
CLM98_RS03720	COG0697	spore germination
CLM98_RS03735	COG1113	amino acid transport
CLM98_RS03755	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CLM98_RS03805	COG5001	Diguanylate cyclase
CLM98_RS03810	COG0840	transmembrane signaling receptor activity
CLM98_RS03815	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLM98_RS03815	COG5297	Belongs to the glycosyl hydrolase family 6
CLM98_RS03820	COG0659	secondary active sulfate transmembrane transporter activity
CLM98_RS03840	COG2943	transferase activity, transferring hexosyl groups
CLM98_RS03850	COG3275	phosphorelay sensor kinase activity
CLM98_RS03860	COG0181	hydroxymethylbilane synthase activity
CLM98_RS03890	COG1505	serine-type exopeptidase activity
CLM98_RS03895	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CLM98_RS03910	COG2832	Protein of unknown function (DUF454)
CLM98_RS03920	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CLM98_RS03930	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CLM98_RS03935	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CLM98_RS03940	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CLM98_RS03965	COG2226	methyltransferase
CLM98_RS03970	COG5001	Diguanylate cyclase
CLM98_RS03970	COG3300	MHYT domain
CLM98_RS03975	COG0308	aminopeptidase N
CLM98_RS04025	COG3284	Transcriptional regulator
CLM98_RS04030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLM98_RS04035	COG1077	Cell shape determining protein MreB Mrl
CLM98_RS04040	COG1792	Involved in formation and maintenance of cell shape
CLM98_RS04055	COG0772	Belongs to the SEDS family
CLM98_RS04065	COG2951	lytic endotransglycosylase activity
CLM98_RS04070	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CLM98_RS04080	COG1686	Belongs to the peptidase S11 family
CLM98_RS04090	COG2921	Belongs to the UPF0250 family
CLM98_RS04095	COG0321	lipoyl(octanoyl) transferase activity
CLM98_RS04100	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CLM98_RS04115	COG0583	DNA-binding transcription factor activity
CLM98_RS04125	COG1051	belongs to the nudix hydrolase family
CLM98_RS04125	COG1056	cytidyltransferase-related domain
CLM98_RS04160	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CLM98_RS04165	COG0673	inositol 2-dehydrogenase activity
CLM98_RS04170	COG2823	Periplasmic or secreted lipoprotein
CLM98_RS04175	COG4251	negative regulation of phosphorylation
CLM98_RS04180	COG0784	Response regulator, receiver
CLM98_RS04185	COG4191	Histidine kinase
CLM98_RS04190	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CLM98_RS04250	COG1459	type II secretion system
CLM98_RS04315	COG2188	Transcriptional regulator
CLM98_RS04325	COG1609	Transcriptional regulator
CLM98_RS04330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CLM98_RS04335	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CLM98_RS04345	COG0617	tRNA 3'-terminal CCA addition
CLM98_RS04350	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CLM98_RS04355	COG1012	belongs to the aldehyde dehydrogenase family
CLM98_RS04360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLM98_RS04375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CLM98_RS04390	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CLM98_RS04395	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CLM98_RS04415	COG2205	protein histidine kinase activity
CLM98_RS04445	COG3791	Glutathione-dependent formaldehyde-activating
CLM98_RS04460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM98_RS04470	COG0697	spore germination
CLM98_RS04480	COG0488	(ABC) transporter
CLM98_RS04490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CLM98_RS04495	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CLM98_RS04505	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLM98_RS04505	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLM98_RS04525	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CLM98_RS04530	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLM98_RS04535	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CLM98_RS04560	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CLM98_RS04565	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CLM98_RS04570	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CLM98_RS04575	COG2205	protein histidine kinase activity
CLM98_RS04580	COG0745	RESPONSE REGULATOR receiver
CLM98_RS04595	COG0277	FAD linked oxidase domain protein
CLM98_RS04600	COG1988	membrane-bound metal-dependent
CLM98_RS04605	COG0792	nuclease activity
CLM98_RS04640	COG0275	rRNA processing
CLM98_RS04645	COG3116	cell division
CLM98_RS04655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLM98_RS04660	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CLM98_RS04665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLM98_RS04675	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLM98_RS04680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLM98_RS04685	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLM98_RS04690	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CLM98_RS04705	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CLM98_RS04715	COG0739	heme binding
CLM98_RS04720	COG0653	protein targeting
CLM98_RS04725	COG0494	nUDIX hydrolase
CLM98_RS04735	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CLM98_RS04750	COG0604	alcohol dehydrogenase
CLM98_RS04750	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS04750	COG3321	synthase
CLM98_RS04780	COG0366	Alpha amylase catalytic
CLM98_RS04810	COG2226	methyltransferase
CLM98_RS04815	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CLM98_RS04830	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CLM98_RS04875	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CLM98_RS04885	COG4106	trans-aconitate 2-methyltransferase activity
CLM98_RS04890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLM98_RS04900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLM98_RS04905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLM98_RS04915	COG0667	Aldo Keto reductase
CLM98_RS04925	COG4771	TonB-dependent receptor
CLM98_RS04945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM98_RS04950	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CLM98_RS04960	COG2175	clavaminate synthase activity
CLM98_RS04970	COG4181	ATPase activity
CLM98_RS04985	COG0642	Histidine kinase
CLM98_RS05000	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CLM98_RS05020	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CLM98_RS05025	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLM98_RS05040	COG3829	transcription factor binding
CLM98_RS05050	COG1116	anion transmembrane transporter activity
CLM98_RS05055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM98_RS05065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLM98_RS05070	COG0431	NADPH-dependent FMN reductase
CLM98_RS05095	COG0747	negative chemotaxis
CLM98_RS05105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM98_RS05115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CLM98_RS05120	COG2967	ApaG domain
CLM98_RS05125	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CLM98_RS05130	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CLM98_RS05135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLM98_RS05140	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CLM98_RS05155	COG0123	including yeast histone deacetylase and acetoin utilization protein
CLM98_RS05160	COG2096	Adenosyltransferase
CLM98_RS05175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLM98_RS05180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLM98_RS05210	COG3384	dioxygenase
CLM98_RS05215	COG0583	DNA-binding transcription factor activity
CLM98_RS05230	COG1024	Enoyl-CoA hydratase
CLM98_RS05250	COG3386	PFAM SMP-30 Gluconolaconase
CLM98_RS05265	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CLM98_RS05285	COG0697	spore germination
CLM98_RS05295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLM98_RS05315	COG0784	Response regulator, receiver
CLM98_RS05315	COG2205	protein histidine kinase activity
CLM98_RS05315	COG5002	protein histidine kinase activity
CLM98_RS05320	COG2197	response regulator
CLM98_RS05330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLM98_RS05340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CLM98_RS05345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLM98_RS05360	COG0583	DNA-binding transcription factor activity
CLM98_RS05365	COG3634	alkyl hydroperoxide reductase activity
CLM98_RS05375	COG2890	protein-(glutamine-N5) methyltransferase activity
CLM98_RS05395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLM98_RS05395	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLM98_RS05425	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CLM98_RS05455	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CLM98_RS05470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLM98_RS05475	COG1404	Belongs to the peptidase S8 family
CLM98_RS05480	COG1404	Belongs to the peptidase S8 family
CLM98_RS05485	COG1404	Belongs to the peptidase S8 family
CLM98_RS05490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLM98_RS05515	COG1295	ribonuclease BN
CLM98_RS05520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLM98_RS05525	COG1254	Belongs to the acylphosphatase family
CLM98_RS05540	COG0521	Mo-molybdopterin cofactor biosynthetic process
CLM98_RS05550	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CLM98_RS05555	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CLM98_RS05565	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CLM98_RS05570	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CLM98_RS05580	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLM98_RS05585	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CLM98_RS05590	COG0193	aminoacyl-tRNA hydrolase activity
CLM98_RS05595	COG0012	GTP binding
CLM98_RS05615	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLM98_RS05630	COG0250	Participates in transcription elongation, termination and antitermination
CLM98_RS05635	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CLM98_RS05640	COG0081	regulation of translation
CLM98_RS05645	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CLM98_RS05650	COG0222	ribosome binding
CLM98_RS05655	COG0085	RNA polymerase activity
CLM98_RS05660	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLM98_RS05665	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CLM98_RS05670	COG0049	tRNA binding
CLM98_RS05675	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLM98_RS05680	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLM98_RS05685	COG0051	transcription antitermination factor activity, RNA binding
CLM98_RS05690	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CLM98_RS05695	COG0088	Forms part of the polypeptide exit tunnel
CLM98_RS05700	COG0089	rRNA binding
CLM98_RS05705	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CLM98_RS05710	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CLM98_RS05720	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CLM98_RS05725	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CLM98_RS05730	COG0255	Belongs to the universal ribosomal protein uL29 family
CLM98_RS05735	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CLM98_RS05745	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CLM98_RS05750	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CLM98_RS05760	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CLM98_RS05765	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CLM98_RS05770	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CLM98_RS05780	COG1841	ribosomal large subunit assembly
CLM98_RS05785	COG0200	Binds to the 23S rRNA
CLM98_RS05790	COG0201	protein transport
CLM98_RS05815	COG0203	ribosomal protein L17
CLM98_RS05820	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CLM98_RS05840	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CLM98_RS05850	COG0154	amidase activity
CLM98_RS05860	COG1217	gtp-binding protein TYPA
CLM98_RS05865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLM98_RS05870	COG0039	L-malate dehydrogenase activity
CLM98_RS05875	COG0625	glutathione transferase activity
CLM98_RS05895	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLM98_RS05895	COG1902	pentaerythritol trinitrate reductase activity
CLM98_RS05900	COG0604	alcohol dehydrogenase
CLM98_RS05930	COG0156	8-amino-7-oxononanoate synthase activity
CLM98_RS05935	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CLM98_RS05940	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CLM98_RS05945	COG4208	sulfate ABC transporter
CLM98_RS05950	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CLM98_RS05960	COG1063	alcohol dehydrogenase
CLM98_RS05995	COG0406	alpha-ribazole phosphatase activity
CLM98_RS06000	COG0285	dihydrofolate synthase activity
CLM98_RS06020	COG2833	Protein of unknown function (DUF455)
CLM98_RS06030	COG3291	Pkd domain containing protein
CLM98_RS06040	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLM98_RS06045	COG0671	phosphoesterase, PA-phosphatase related
CLM98_RS06050	COG0438	transferase activity, transferring glycosyl groups
CLM98_RS06060	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CLM98_RS06075	COG4783	chaperone-mediated protein folding
CLM98_RS06090	COG0473	3-isopropylmalate dehydrogenase activity
CLM98_RS06245	COG0544	peptidyl-prolyl cis-trans isomerase activity
CLM98_RS06255	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CLM98_RS06285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLM98_RS06295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLM98_RS06305	COG0328	RNA-DNA hybrid ribonuclease activity
CLM98_RS06310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLM98_RS06315	COG0631	protein serine/threonine phosphatase activity
CLM98_RS06330	COG0859	PFAM glycosyl transferase family 9
CLM98_RS06335	COG3642	lipopolysaccharide core region biosynthetic process
CLM98_RS06340	COG1234	tRNA 3'-trailer cleavage
CLM98_RS06345	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CLM98_RS06355	COG0315	cyclic pyranopterin monophosphate synthase activity
CLM98_RS06360	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CLM98_RS06365	COG0314	molybdopterin synthase activity
CLM98_RS06420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CLM98_RS06425	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CLM98_RS06430	COG0537	adenosine 5'-monophosphoramidase activity
CLM98_RS06450	COG0714	Associated with various cellular activities
CLM98_RS06470	COG0424	maF-like protein
CLM98_RS06475	COG1399	metal-binding, possibly nucleic acid-binding protein
CLM98_RS06480	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CLM98_RS06485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLM98_RS06500	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS06515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CLM98_RS06520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CLM98_RS06545	COG3829	transcription factor binding
CLM98_RS06565	COG3609	addiction module antidote protein, CC2985 family
CLM98_RS06600	COG2373	Large extracellular alpha-helical protein
CLM98_RS06620	COG4953	penicillin-binding protein 1C
CLM98_RS06630	COG0678	peroxiredoxin activity
CLM98_RS06650	COG0330	HflC and HflK could
CLM98_RS06655	COG0330	HflC and HflK could
CLM98_RS06665	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CLM98_RS06670	COG0308	aminopeptidase N
CLM98_RS06675	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS06680	COG1309	transcriptional regulator
CLM98_RS06760	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CLM98_RS06770	COG3387	PFAM Glycoside hydrolase 15-related
CLM98_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS06785	COG3537	Alpha-1,2-mannosidase
CLM98_RS06805	COG0492	ferredoxin-NADP+ reductase activity
CLM98_RS06830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CLM98_RS06835	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CLM98_RS06840	COG2080	2 iron, 2 sulfur cluster binding
CLM98_RS06875	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CLM98_RS06890	COG0587	DNA-directed DNA polymerase activity
CLM98_RS06910	COG1297	OPT oligopeptide transporter protein
CLM98_RS06925	COG0823	Involved in the tonB-independent uptake of proteins
CLM98_RS06925	COG1506	peptidase
CLM98_RS06940	COG1917	Cupin 2, conserved barrel domain protein
CLM98_RS06940	COG2207	Transcriptional regulator
CLM98_RS06960	COG0753	catalase activity
CLM98_RS06965	COG0656	L-ascorbic acid biosynthetic process
CLM98_RS06975	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CLM98_RS06975	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CLM98_RS06980	COG2814	Major facilitator Superfamily
CLM98_RS07010	COG0745	RESPONSE REGULATOR receiver
CLM98_RS07015	COG0642	Histidine kinase
CLM98_RS07025	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CLM98_RS07030	COG2894	cell division
CLM98_RS07035	COG0850	regulation of cytokinetic process
CLM98_RS07050	COG4585	Histidine kinase
CLM98_RS07055	COG2197	response regulator
CLM98_RS07070	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CLM98_RS07100	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CLM98_RS07110	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CLM98_RS07130	COG1946	Acyl-CoA thioesterase
CLM98_RS07145	COG0824	Thioesterase
CLM98_RS07150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CLM98_RS07155	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CLM98_RS07160	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CLM98_RS07165	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CLM98_RS07170	COG0268	Binds directly to 16S ribosomal RNA
CLM98_RS07180	COG0196	riboflavin kinase activity
CLM98_RS07185	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CLM98_RS07190	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CLM98_RS07195	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CLM98_RS07210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CLM98_RS07215	COG1845	cytochrome c oxidase, subunit III
CLM98_RS07220	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CLM98_RS07235	COG3152	Membrane
CLM98_RS07245	COG2207	Transcriptional regulator
CLM98_RS07250	COG0326	Molecular chaperone. Has ATPase activity
CLM98_RS07260	COG1366	Belongs to the anti-sigma-factor antagonist family
CLM98_RS07265	COG1366	Belongs to the anti-sigma-factor antagonist family
CLM98_RS07270	COG2172	sigma factor antagonist activity
CLM98_RS07295	COG4771	TonB-dependent receptor
CLM98_RS07305	COG5507	3-demethylubiquinone-9 3-methyltransferase
CLM98_RS07310	COG2205	protein histidine kinase activity
CLM98_RS07320	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CLM98_RS07325	COG3850	Histidine kinase
CLM98_RS07325	COG4999	Histidine kinase
CLM98_RS07325	COG3437	response regulator, receiver
CLM98_RS07325	COG2205	protein histidine kinase activity
CLM98_RS07330	COG4191	Histidine kinase
CLM98_RS07330	COG0784	Response regulator, receiver
CLM98_RS07355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLM98_RS07365	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CLM98_RS07380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLM98_RS07385	COG0228	four-way junction DNA binding
CLM98_RS07390	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CLM98_RS07395	COG0336	Belongs to the RNA methyltransferase TrmD family
CLM98_RS07400	COG0335	large ribosomal subunit rRNA binding
CLM98_RS07425	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CLM98_RS07435	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CLM98_RS07445	COG3209	COG3209 Rhs family protein
CLM98_RS07470	COG3250	beta-galactosidase activity
CLM98_RS07475	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CLM98_RS07495	COG1960	acyl-CoA dehydrogenase activity
CLM98_RS07500	COG1024	Enoyl-CoA hydratase
CLM98_RS07520	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLM98_RS07520	COG1024	Enoyl-CoA hydratase
CLM98_RS07535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLM98_RS07540	COG0481	GTPase activity
CLM98_RS07555	COG0571	ribonuclease III activity
CLM98_RS07565	COG1381	Involved in DNA repair and RecF pathway recombination
CLM98_RS07575	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLM98_RS07580	COG2954	triphosphatase activity
CLM98_RS07585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CLM98_RS07590	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
CLM98_RS07595	COG3046	protein related to deoxyribodipyrimidine photolyase
CLM98_RS07600	COG1472	Belongs to the glycosyl hydrolase 3 family
CLM98_RS07605	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CLM98_RS07610	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CLM98_RS07615	COG1278	Cold shock
CLM98_RS07620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLM98_RS07630	COG1201	RNA secondary structure unwinding
CLM98_RS07635	COG1793	dna ligase
CLM98_RS07645	COG1793	dna ligase
CLM98_RS07645	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CLM98_RS07675	COG0183	Belongs to the thiolase family
CLM98_RS07700	COG1451	nucleotide metabolic process
CLM98_RS07705	COG5487	UPF0391 membrane protein
CLM98_RS07715	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CLM98_RS07730	COG1077	Cell shape determining protein MreB Mrl
CLM98_RS07735	COG1047	Peptidyl-prolyl cis-trans
CLM98_RS07745	COG2824	Alkylphosphonate utilization operon protein PhnA
CLM98_RS07755	COG1902	pentaerythritol trinitrate reductase activity
CLM98_RS07760	COG2814	Major facilitator Superfamily
CLM98_RS07790	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CLM98_RS07790	COG0392	lysyltransferase activity
CLM98_RS07800	COG0251	oxidation-reduction process
CLM98_RS07805	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CLM98_RS07820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CLM98_RS07845	COG1595	DNA-templated transcription, initiation
CLM98_RS07865	COG2878	Part of a membrane complex involved in electron transport
CLM98_RS07875	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLM98_RS07875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLM98_RS07890	COG1131	(ABC) transporter
CLM98_RS07895	COG0346	lactoylglutathione lyase activity
CLM98_RS07900	COG0833	amino acid
CLM98_RS07905	COG2040	homocysteine
CLM98_RS07915	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CLM98_RS07935	COG1695	Transcriptional regulator
CLM98_RS07955	COG1981	membrane
CLM98_RS07970	COG0825	malonyl-CoA metabolic process
CLM98_RS07980	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CLM98_RS07985	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLM98_RS07990	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLM98_RS07995	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLM98_RS08000	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLM98_RS08015	COG0750	zinc metalloprotease
CLM98_RS08020	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CLM98_RS08025	COG0575	Belongs to the CDS family
CLM98_RS08030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CLM98_RS08035	COG0233	cytoplasmic translational termination
CLM98_RS08040	COG0528	UMP kinase activity
CLM98_RS08050	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CLM98_RS08055	COG0052	Belongs to the universal ribosomal protein uS2 family
CLM98_RS08095	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CLM98_RS08105	COG1393	Belongs to the ArsC family
CLM98_RS08110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLM98_RS08115	COG0367	asparagine synthase
CLM98_RS08125	COG4774	siderophore transport
CLM98_RS08145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLM98_RS08180	COG1566	PFAM secretion protein HlyD family protein
CLM98_RS08185	COG2814	Major facilitator Superfamily
CLM98_RS08235	COG0339	signal peptide processing
CLM98_RS08245	COG0386	Belongs to the glutathione peroxidase family
CLM98_RS08300	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CLM98_RS08320	COG1960	acyl-CoA dehydrogenase activity
CLM98_RS08340	COG0367	asparagine synthase
CLM98_RS08350	COG0305	Participates in initiation and elongation during chromosome replication
CLM98_RS08355	COG0415	Belongs to the DNA photolyase family
CLM98_RS08375	COG0583	DNA-binding transcription factor activity
CLM98_RS08420	COG3706	GGDEF domain
CLM98_RS08540	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CLM98_RS08555	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLM98_RS08565	COG0497	DNA recombination
CLM98_RS08570	COG1420	regulation of RNA biosynthetic process
CLM98_RS08575	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CLM98_RS08580	COG0443	Heat shock 70 kDa protein
CLM98_RS08585	COG0484	heat shock protein binding
CLM98_RS08595	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CLM98_RS08625	COG0583	DNA-binding transcription factor activity
CLM98_RS08630	COG1132	(ABC) transporter
CLM98_RS08665	COG2850	peptidyl-arginine hydroxylation
CLM98_RS08685	COG1253	flavin adenine dinucleotide binding
CLM98_RS08715	COG1131	(ABC) transporter
CLM98_RS08720	COG1725	Transcriptional regulator
CLM98_RS08730	COG0386	Belongs to the glutathione peroxidase family
CLM98_RS08745	COG2900	Belongs to the SlyX family
CLM98_RS08770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLM98_RS08780	COG1410	methionine synthase
CLM98_RS08780	COG0646	methionine synthase
CLM98_RS08785	COG0646	methionine synthase
CLM98_RS08785	COG1410	methionine synthase
CLM98_RS08790	COG2226	methyltransferase
CLM98_RS08795	COG1960	acyl-CoA dehydrogenase activity
CLM98_RS08800	COG1960	acyl-CoA dehydrogenase activity
CLM98_RS08820	COG0557	exoribonuclease II activity
CLM98_RS08830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLM98_RS08840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLM98_RS08850	COG0704	Plays a role in the regulation of phosphate uptake
CLM98_RS08855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLM98_RS08860	COG0581	inorganic phosphate transmembrane transporter activity
CLM98_RS08865	COG0573	inorganic phosphate transmembrane transporter activity
CLM98_RS08870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CLM98_RS08895	COG0659	secondary active sulfate transmembrane transporter activity
CLM98_RS08900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CLM98_RS08910	COG1024	Enoyl-CoA hydratase
CLM98_RS08920	COG0494	nUDIX hydrolase
CLM98_RS08955	COG0488	(ABC) transporter
CLM98_RS08965	COG0116	Belongs to the methyltransferase superfamily
CLM98_RS08965	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CLM98_RS08970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLM98_RS08995	COG2925	Exonuclease
CLM98_RS09005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLM98_RS09010	COG3844	kynureninase activity
CLM98_RS09020	COG0662	Cupin 2, conserved barrel domain protein
CLM98_RS09025	COG0288	reversible hydration of carbon dioxide
CLM98_RS09090	COG2808	Putative FMN-binding domain
CLM98_RS09110	COG0017	Asparaginyl-tRNA synthetase
CLM98_RS09120	COG0316	Belongs to the HesB IscA family
CLM98_RS09125	COG0360	Binds together with S18 to 16S ribosomal RNA
CLM98_RS09130	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CLM98_RS09135	COG0359	binds to the 23S rRNA
CLM98_RS09145	COG3115	cell septum assembly
CLM98_RS09155	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLM98_RS09160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLM98_RS09165	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CLM98_RS09180	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CLM98_RS09200	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CLM98_RS09210	COG2986	histidine ammonia-lyase
CLM98_RS09215	COG1228	amidohydrolase
CLM98_RS09260	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CLM98_RS09265	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CLM98_RS09270	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CLM98_RS09275	COG0077	Prephenate dehydratase
CLM98_RS09275	COG1605	Chorismate mutase
CLM98_RS09280	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CLM98_RS09295	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CLM98_RS09300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CLM98_RS09305	COG0583	DNA-binding transcription factor activity
CLM98_RS09365	COG0840	transmembrane signaling receptor activity
CLM98_RS09400	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CLM98_RS09405	COG0784	Response regulator, receiver
CLM98_RS09405	COG4191	Histidine kinase
CLM98_RS09420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLM98_RS09430	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CLM98_RS09440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLM98_RS09455	COG1595	DNA-templated transcription, initiation
CLM98_RS09510	COG2244	polysaccharide biosynthetic process
CLM98_RS09545	COG2264	protein methyltransferase activity
CLM98_RS09555	COG0438	transferase activity, transferring glycosyl groups
CLM98_RS09570	COG1136	(ABC) transporter
CLM98_RS09580	COG0477	Major facilitator Superfamily
CLM98_RS09585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLM98_RS09600	COG1253	flavin adenine dinucleotide binding
CLM98_RS09615	COG0306	phosphate transporter
CLM98_RS09645	COG0504	CTP synthase activity
CLM98_RS09650	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CLM98_RS09660	COG0148	phosphopyruvate hydratase activity
CLM98_RS09665	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CLM98_RS09670	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CLM98_RS09675	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CLM98_RS09680	COG0585	pseudouridine synthase activity
CLM98_RS09685	COG2840	Smr protein MutS2
CLM98_RS09690	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CLM98_RS09695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CLM98_RS09700	COG1238	metal cluster binding
CLM98_RS09715	COG1534	Rna-binding protein
CLM98_RS09720	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CLM98_RS09730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CLM98_RS09735	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CLM98_RS09745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CLM98_RS09750	COG1546	Belongs to the CinA family
CLM98_RS09760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CLM98_RS09765	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CLM98_RS09775	COG2137	regulation of response to DNA damage stimulus
CLM98_RS09780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CLM98_RS09785	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CLM98_RS09805	COG1741	Belongs to the pirin family
CLM98_RS09810	COG0583	DNA-binding transcription factor activity
CLM98_RS09835	COG0351	phosphomethylpyrimidine kinase
CLM98_RS09835	COG0352	thiamine-phosphate diphosphorylase activity
CLM98_RS09850	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CLM98_RS09855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CLM98_RS09870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLM98_RS09880	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CLM98_RS09885	COG3734	2-keto-3-deoxy-galactonokinase
CLM98_RS09895	COG4948	Mandelate Racemase Muconate Lactonizing
CLM98_RS09900	COG0800	Aldolase
CLM98_RS09940	COG1501	Belongs to the glycosyl hydrolase 31 family
CLM98_RS09950	COG1070	Carbohydrate kinase
CLM98_RS09955	COG2115	Belongs to the xylose isomerase family
CLM98_RS09960	COG0477	Major facilitator Superfamily
CLM98_RS09980	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLM98_RS09985	COG1469	GTP cyclohydrolase I activity
CLM98_RS10005	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CLM98_RS10010	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CLM98_RS10015	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CLM98_RS10020	COG0166	Belongs to the GPI family
CLM98_RS10045	COG1472	Belongs to the glycosyl hydrolase 3 family
CLM98_RS10060	COG4251	negative regulation of phosphorylation
CLM98_RS10060	COG3706	GGDEF domain
CLM98_RS10060	COG2203	Gaf domain
CLM98_RS10060	COG5001	Diguanylate cyclase
CLM98_RS10070	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLM98_RS10075	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CLM98_RS10085	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CLM98_RS10090	COG0671	phosphoesterase, PA-phosphatase related
CLM98_RS10105	COG1794	racemase activity, acting on amino acids and derivatives
CLM98_RS10115	COG0697	spore germination
CLM98_RS10120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CLM98_RS10125	COG0167	dihydroorotate dehydrogenase activity
CLM98_RS10145	COG1012	belongs to the aldehyde dehydrogenase family
CLM98_RS10160	COG1215	transferase activity, transferring glycosyl groups
CLM98_RS10165	COG1649	PFAM Uncharacterised BCR, COG1649
CLM98_RS10165	COG0726	polysaccharide deacetylase
CLM98_RS10180	COG3210	domain, Protein
CLM98_RS10190	COG3210	domain, Protein
CLM98_RS10235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLM98_RS10240	COG0124	histidyl-tRNA synthetase
CLM98_RS10250	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CLM98_RS10255	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CLM98_RS10260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLM98_RS10265	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CLM98_RS10265	COG0131	Imidazoleglycerol-phosphate dehydratase
CLM98_RS10270	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CLM98_RS10275	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CLM98_RS10280	COG0107	imidazoleglycerol-phosphate synthase activity
CLM98_RS10285	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CLM98_RS10285	COG0140	phosphoribosyl-ATP diphosphatase activity
CLM98_RS10300	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CLM98_RS10305	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CLM98_RS10310	COG0235	Class ii aldolase
CLM98_RS10315	COG0531	amino acid
CLM98_RS10320	COG0531	amino acid
CLM98_RS10330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLM98_RS10335	COG0277	FAD linked oxidase domain protein
CLM98_RS10355	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLM98_RS10400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM98_RS10405	COG2258	MOSC domain
CLM98_RS10410	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CLM98_RS10415	COG0505	Belongs to the CarA family
CLM98_RS10425	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CLM98_RS10430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLM98_RS10440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CLM98_RS10480	COG3279	Response regulator of the LytR AlgR family
CLM98_RS10490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CLM98_RS10500	COG2205	protein histidine kinase activity
CLM98_RS10500	COG0784	Response regulator, receiver
CLM98_RS10500	COG2198	Histidine kinase
CLM98_RS10505	COG1024	Enoyl-CoA hydratase
CLM98_RS10510	COG0318	PFAM AMP-dependent synthetase and ligase
CLM98_RS10540	COG2267	carboxylic ester hydrolase activity
CLM98_RS10550	COG2201	protein-glutamate methylesterase activity
CLM98_RS10555	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CLM98_RS10565	COG0840	transmembrane signaling receptor activity
CLM98_RS10575	COG0835	chemotaxis
CLM98_RS10590	COG0840	transmembrane signaling receptor activity
CLM98_RS10595	COG0840	transmembrane signaling receptor activity
CLM98_RS10610	COG0840	transmembrane signaling receptor activity
CLM98_RS10620	COG0840	transmembrane signaling receptor activity
CLM98_RS10625	COG0840	transmembrane signaling receptor activity
CLM98_RS10630	COG0840	transmembrane signaling receptor activity
CLM98_RS10635	COG0840	transmembrane signaling receptor activity
CLM98_RS10650	COG0840	transmembrane signaling receptor activity
CLM98_RS10670	COG2198	Histidine kinase
CLM98_RS10670	COG0643	Histidine kinase
CLM98_RS10675	COG0745	RESPONSE REGULATOR receiver
CLM98_RS10685	COG0835	chemotaxis
CLM98_RS10695	COG1360	Flagellar Motor Protein
CLM98_RS10700	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CLM98_RS10825	COG0641	radical SAM
CLM98_RS10845	COG2198	Histidine kinase
CLM98_RS10845	COG0784	Response regulator, receiver
CLM98_RS10845	COG0643	Histidine kinase
CLM98_RS10875	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLM98_RS10905	COG1684	flagellar biosynthetic protein fliR
CLM98_RS10925	COG3190	flagellar
CLM98_RS10975	COG1677	Flagellar hook-basal body complex protein FliE
CLM98_RS11005	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS11010	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS11015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLM98_RS11035	COG2201	protein-glutamate methylesterase activity
CLM98_RS11065	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CLM98_RS11070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CLM98_RS11075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CLM98_RS11085	COG1705	Flagellar rod assembly protein muramidase FlgJ
CLM98_RS11085	COG3951	Flagellar rod assembly protein muramidase FlgJ
CLM98_RS11090	COG1706	bacterial-type flagellum-dependent cell motility
CLM98_RS11095	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CLM98_RS11105	COG4787	bacterial-type flagellum-dependent cell motility
CLM98_RS11115	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CLM98_RS11120	COG1558	bacterial-type flagellum-dependent cell motility
CLM98_RS11130	COG0835	chemotaxis
CLM98_RS11130	COG0784	Response regulator, receiver
CLM98_RS11150	COG5002	protein histidine kinase activity
CLM98_RS11180	COG2915	High frequency lysogenization protein hflD homolog
CLM98_RS11185	COG0482	sulfurtransferase activity
CLM98_RS11200	COG0542	response to heat
CLM98_RS11210	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CLM98_RS11220	COG0492	ferredoxin-NADP+ reductase activity
CLM98_RS11225	COG1674	ftsk spoiiie
CLM98_RS11235	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CLM98_RS11245	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CLM98_RS11250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CLM98_RS11260	COG0183	Belongs to the thiolase family
CLM98_RS11265	COG1024	Enoyl-CoA hydratase
CLM98_RS11265	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLM98_RS11280	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CLM98_RS11290	COG1426	Protein conserved in bacteria
CLM98_RS11300	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLM98_RS11305	COG1160	GTP binding
CLM98_RS11310	COG0303	'Molybdopterin
CLM98_RS11315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CLM98_RS11355	COG0708	Exodeoxyribonuclease III
CLM98_RS11365	COG0303	'Molybdopterin
CLM98_RS11370	COG0746	molybdenum cofactor guanylyltransferase activity
CLM98_RS11385	COG1914	H( )-stimulated, divalent metal cation uptake system
CLM98_RS11400	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CLM98_RS11405	COG0668	transmembrane transport
CLM98_RS11415	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CLM98_RS11430	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS11435	COG1183	phosphatidylcholine synthase activity
CLM98_RS11445	COG3243	poly(R)-hydroxyalkanoic acid synthase
CLM98_RS11460	COG0723	plastoquinol--plastocyanin reductase activity
CLM98_RS11460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM98_RS11470	COG2183	response to ionizing radiation
CLM98_RS11475	COG0784	Response regulator, receiver
CLM98_RS11475	COG2205	protein histidine kinase activity
CLM98_RS11550	COG0800	Aldolase
CLM98_RS11555	COG0129	dihydroxy-acid dehydratase activity
CLM98_RS11560	COG0363	glucosamine-6-phosphate deaminase activity
CLM98_RS11565	COG0837	glucose binding
CLM98_RS11570	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CLM98_RS11595	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CLM98_RS11610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CLM98_RS11615	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CLM98_RS11625	COG4591	ABC-type transport system involved in lipoprotein release permease component
CLM98_RS11630	COG1136	(ABC) transporter
CLM98_RS11645	COG0811	peptide transport
CLM98_RS11655	COG1132	(ABC) transporter
CLM98_RS11660	COG1663	tetraacyldisaccharide 4'-kinase activity
CLM98_RS11665	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CLM98_RS11670	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLM98_RS11680	COG0322	excinuclease ABC activity
CLM98_RS11685	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLM98_RS11705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLM98_RS11710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLM98_RS11735	COG0582	viral genome integration into host DNA
CLM98_RS11745	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CLM98_RS11765	COG1054	Belongs to the UPF0176 family
CLM98_RS11775	COG1530	ribonuclease E activity
CLM98_RS11785	COG3064	Membrane
CLM98_RS11790	COG0428	transporter
CLM98_RS11800	COG2154	pterin-4-alpha-carbinolamine dehydratase
CLM98_RS11805	COG0316	Belongs to the HesB IscA family
CLM98_RS11805	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CLM98_RS11860	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS11945	COG1238	metal cluster binding
CLM98_RS11980	COG3279	Response regulator of the LytR AlgR family
CLM98_RS12030	COG4566	intracellular signal transduction
CLM98_RS12040	COG5001	Diguanylate cyclase
CLM98_RS12060	COG3685	Protein conserved in bacteria
CLM98_RS12085	COG1648	precorrin-2 dehydrogenase activity
CLM98_RS12085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CLM98_RS12100	COG2814	Major facilitator Superfamily
CLM98_RS12115	COG1335	isochorismatase
CLM98_RS12130	COG2197	response regulator
CLM98_RS12150	COG0583	DNA-binding transcription factor activity
CLM98_RS12155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CLM98_RS12160	COG3002	Belongs to the UPF0753 family
CLM98_RS12170	COG1396	sequence-specific DNA binding
CLM98_RS12175	COG5489	Protein of unknown function (DUF736)
CLM98_RS12180	COG2003	Belongs to the UPF0758 family
CLM98_RS12205	COG0582	viral genome integration into host DNA
CLM98_RS12220	COG4774	siderophore transport
CLM98_RS12240	COG2336	PFAM SpoVT AbrB
CLM98_RS12265	COG4206	TonB-dependent receptor
CLM98_RS12305	COG2274	protein secretion by the type I secretion system
CLM98_RS12360	COG0270	DNA (cytosine-5-)-methyltransferase activity
CLM98_RS12425	COG5006	permease, DMT superfamily
CLM98_RS12440	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLM98_RS12450	COG3938	Belongs to the proline racemase family
CLM98_RS12465	COG2807	transmembrane transport
CLM98_RS12470	COG2207	Transcriptional regulator
CLM98_RS12615	COG0210	DNA helicase
CLM98_RS12695	COG2084	Dehydrogenase
CLM98_RS12715	COG2003	Belongs to the UPF0758 family
CLM98_RS12750	COG0582	viral genome integration into host DNA
CLM98_RS12760	COG0519	Catalyzes the synthesis of GMP from XMP
CLM98_RS12760	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CLM98_RS12770	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CLM98_RS12780	COG0475	glutathione-regulated potassium exporter activity
CLM98_RS12780	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CLM98_RS12790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CLM98_RS12800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLM98_RS12805	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CLM98_RS12815	COG0776	regulation of translation
CLM98_RS12820	COG0539	negative regulation of cytoplasmic translation
CLM98_RS12825	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CLM98_RS12845	COG2957	Belongs to the agmatine deiminase family
CLM98_RS12850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLM98_RS12875	COG0395	ABC-type sugar transport system, permease component
CLM98_RS12880	COG1175	transmembrane transport
CLM98_RS12910	COG2350	Protein conserved in bacteria
CLM98_RS12915	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CLM98_RS12920	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CLM98_RS12925	COG1187	pseudouridine synthase activity
CLM98_RS12945	COG0436	Aminotransferase
CLM98_RS12950	COG4133	protoheme IX ABC transporter activity
CLM98_RS12970	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CLM98_RS12975	COG1138	Cytochrome C-type biogenesis protein
CLM98_RS12995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CLM98_RS13000	COG1278	Cold shock
CLM98_RS13005	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CLM98_RS13010	COG4988	ABC transporter
CLM98_RS13020	COG1294	oxidase, subunit
CLM98_RS13050	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CLM98_RS13055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CLM98_RS13065	COG0165	Argininosuccinate lyase
CLM98_RS13070	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CLM98_RS13080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CLM98_RS13085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLM98_RS13095	COG0137	argininosuccinate synthase activity
CLM98_RS13100	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CLM98_RS13110	COG0215	cysteine-tRNA ligase activity
CLM98_RS13115	COG2166	iron-sulfur cluster assembly
CLM98_RS13130	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CLM98_RS13135	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CLM98_RS13165	COG4302	ethanolamine ammonia-lyase activity
CLM98_RS13225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CLM98_RS13230	COG0402	S-adenosylhomocysteine deaminase activity
CLM98_RS13240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLM98_RS13245	COG1509	lysine 2,3-aminomutase activity
CLM98_RS13250	COG3300	MHYT domain
CLM98_RS13250	COG5001	Diguanylate cyclase
CLM98_RS13265	COG0483	inositol monophosphate 1-phosphatase activity
CLM98_RS13270	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CLM98_RS13290	COG0488	(ABC) transporter
CLM98_RS13295	COG0513	Belongs to the DEAD box helicase family
CLM98_RS13300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLM98_RS13305	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CLM98_RS13315	COG0625	glutathione transferase activity
CLM98_RS13325	COG4681	YaeQ
CLM98_RS13330	COG2081	HI0933 family
CLM98_RS13340	COG0501	Belongs to the peptidase M48B family
CLM98_RS13345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLM98_RS13350	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS13375	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CLM98_RS13380	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLM98_RS13385	COG0802	atpase or kinase
CLM98_RS13390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CLM98_RS13390	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CLM98_RS13395	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CLM98_RS13400	COG1570	exodeoxyribonuclease VII activity
CLM98_RS13410	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CLM98_RS13595	COG0835	chemotaxis
CLM98_RS13600	COG0840	transmembrane signaling receptor activity
CLM98_RS13605	COG2094	Belongs to the DNA glycosylase MPG family
CLM98_RS13610	COG1201	RNA secondary structure unwinding
CLM98_RS13630	COG2969	positive regulation of protein catabolic process
CLM98_RS13635	COG0625	glutathione transferase activity
CLM98_RS13640	COG2857	Cytochrome c1
CLM98_RS13645	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CLM98_RS13650	COG0723	plastoquinol--plastocyanin reductase activity
CLM98_RS13660	COG0741	lytic transglycosylase activity
CLM98_RS13675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLM98_RS13680	COG1702	phosphate starvation-inducible protein PhoH
CLM98_RS13690	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CLM98_RS13700	COG4535	Mg2 and Co2 transporter CorC
CLM98_RS13715	COG1012	belongs to the aldehyde dehydrogenase family
CLM98_RS13720	COG1177	transmembrane transport
CLM98_RS13725	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLM98_RS13730	COG3842	ATPase activity
CLM98_RS13750	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CLM98_RS13765	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CLM98_RS13770	COG0174	glutamine synthetase
CLM98_RS13775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM98_RS13785	COG2703	oxygen carrier activity
CLM98_RS13790	COG0477	Major facilitator Superfamily
CLM98_RS13800	COG0243	molybdopterin cofactor binding
CLM98_RS13805	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CLM98_RS13810	COG2223	nitrite transmembrane transporter activity
CLM98_RS13825	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CLM98_RS13835	COG2733	membrane
CLM98_RS13840	COG2205	protein histidine kinase activity
CLM98_RS13840	COG5002	protein histidine kinase activity
CLM98_RS13840	COG0784	Response regulator, receiver
CLM98_RS13850	COG0477	Major facilitator Superfamily
CLM98_RS13860	COG2902	Dehydrogenase
CLM98_RS13870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM98_RS13875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM98_RS13880	COG1609	Transcriptional regulator
CLM98_RS13885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLM98_RS13885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLM98_RS13890	COG1105	Belongs to the carbohydrate kinase PfkB family
CLM98_RS13895	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLM98_RS13895	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLM98_RS13940	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLM98_RS13950	COG1862	Preprotein translocase
CLM98_RS13955	COG0343	queuine tRNA-ribosyltransferase activity
CLM98_RS13960	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CLM98_RS14000	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CLM98_RS14005	COG3291	Pkd domain containing protein
CLM98_RS14010	COG0405	Gamma-glutamyltransferase
CLM98_RS14015	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLM98_RS14030	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CLM98_RS14035	COG0742	ribosomal rna small subunit methyltransferase
CLM98_RS14040	COG0326	Molecular chaperone. Has ATPase activity
CLM98_RS14130	COG0531	amino acid
CLM98_RS14145	COG0006	proline dipeptidase activity
CLM98_RS14155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLM98_RS14170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM98_RS14175	COG3938	Belongs to the proline racemase family
CLM98_RS14185	COG0552	protein localization to endoplasmic reticulum
CLM98_RS14195	COG1194	a g-specific adenine glycosylase
CLM98_RS14200	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CLM98_RS14205	COG0784	Response regulator, receiver
CLM98_RS14205	COG4191	Histidine kinase
CLM98_RS14220	COG0322	excinuclease ABC activity
CLM98_RS14235	COG3040	lipid binding
CLM98_RS14250	COG1960	acyl-CoA dehydrogenase activity
CLM98_RS14260	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CLM98_RS14280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLM98_RS14285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLM98_RS14290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLM98_RS14315	COG0438	transferase activity, transferring glycosyl groups
CLM98_RS14325	COG0438	transferase activity, transferring glycosyl groups
CLM98_RS14330	COG0438	transferase activity, transferring glycosyl groups
CLM98_RS14380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLM98_RS14380	COG0072	phenylalanine-tRNA ligase activity
CLM98_RS14385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CLM98_RS14400	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CLM98_RS14405	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLM98_RS14430	COG1082	Xylose isomerase domain protein TIM barrel
CLM98_RS14445	COG0366	Alpha amylase catalytic
CLM98_RS14505	COG3702	type iv secretory pathway
CLM98_RS14525	COG2948	multi-organism process
CLM98_RS14545	COG3505	Type IV secretory pathway VirD4
CLM98_RS14565	COG0556	nucleotide-excision repair
CLM98_RS14655	COG4695	Portal protein
CLM98_RS14700	COG3179	chitinase
CLM98_RS14800	COG3275	phosphorelay sensor kinase activity
CLM98_RS14805	COG1611	Belongs to the LOG family
CLM98_RS14820	COG2095	MarC family integral membrane protein
CLM98_RS14830	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CLM98_RS14865	COG1185	polyribonucleotide nucleotidyltransferase activity
CLM98_RS14870	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CLM98_RS14875	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CLM98_RS14880	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CLM98_RS14885	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CLM98_RS14890	COG0195	Participates in both transcription termination and antitermination
CLM98_RS14895	COG0779	Required for maturation of 30S ribosomal subunits
CLM98_RS14905	COG1007	ATP synthesis coupled electron transport
CLM98_RS14930	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLM98_RS14935	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CLM98_RS14945	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CLM98_RS14950	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CLM98_RS14955	COG0649	NAD binding
CLM98_RS14960	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLM98_RS14965	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLM98_RS14970	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLM98_RS14985	COG0149	triose-phosphate isomerase activity
CLM98_RS14990	COG0300	oxidoreductase activity
CLM98_RS15020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLM98_RS15025	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CLM98_RS15030	COG0159	tryptophan synthase activity
CLM98_RS15040	COG0133	tryptophan synthase activity
CLM98_RS15050	COG0135	phosphoribosylanthranilate isomerase activity
CLM98_RS15055	COG0101	tRNA pseudouridine synthase activity
CLM98_RS15075	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLM98_RS15080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLM98_RS15085	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CLM98_RS15090	COG2890	protein-(glutamine-N5) methyltransferase activity
CLM98_RS15100	COG0688	phosphatidylethanolamine metabolic process
CLM98_RS15115	COG0433	COG0433 Predicted ATPase
CLM98_RS15120	COG0494	nUDIX hydrolase
CLM98_RS15140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLM98_RS15145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLM98_RS15170	COG0717	Belongs to the dCTP deaminase family
CLM98_RS15180	COG0489	protein tyrosine kinase activity
CLM98_RS15200	COG3590	peptidase
CLM98_RS15210	COG3590	peptidase
CLM98_RS15230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLM98_RS15235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM98_RS15240	COG2311	Membrane
CLM98_RS15245	COG1047	Peptidyl-prolyl cis-trans
CLM98_RS15250	COG0791	NLP P60 protein
CLM98_RS15255	COG0791	NLP P60 protein
CLM98_RS15265	COG4106	trans-aconitate 2-methyltransferase activity
CLM98_RS15270	COG1301	dicarboxylic acid transport
CLM98_RS15275	COG1785	Belongs to the alkaline phosphatase family
CLM98_RS15285	COG0037	tRNA processing
CLM98_RS15290	COG1722	exodeoxyribonuclease VII activity
CLM98_RS15295	COG0142	geranyltranstransferase activity
CLM98_RS15300	COG4104	PAAR repeat-containing protein
CLM98_RS15310	COG0312	modulator of DNA gyrase
CLM98_RS15315	COG3028	Belongs to the UPF0307 family
CLM98_RS15320	COG0312	modulator of DNA gyrase
CLM98_RS15330	COG3164	Protein of unknown function
CLM98_RS15340	COG0424	maF-like protein
CLM98_RS15345	COG2968	Membrane
CLM98_RS15360	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CLM98_RS15375	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CLM98_RS15390	COG0495	leucyl-tRNA aminoacylation
CLM98_RS15400	COG3118	belongs to the thioredoxin family
CLM98_RS15430	COG2155	Conserved Protein
CLM98_RS15475	COG1132	(ABC) transporter
CLM98_RS15505	COG1538	Outer membrane efflux protein
CLM98_RS15510	COG0745	RESPONSE REGULATOR receiver
CLM98_RS15515	COG5000	phosphorelay sensor kinase activity
CLM98_RS15515	COG5002	protein histidine kinase activity
CLM98_RS15520	COG0475	glutathione-regulated potassium exporter activity
CLM98_RS15530	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLM98_RS15555	COG1187	pseudouridine synthase activity
CLM98_RS15560	COG5002	protein histidine kinase activity
CLM98_RS15560	COG5001	Diguanylate cyclase
CLM98_RS15680	COG0667	Aldo Keto reductase
CLM98_RS15690	COG2814	Major facilitator Superfamily
CLM98_RS15695	COG0583	DNA-binding transcription factor activity
CLM98_RS15705	COG2207	Transcriptional regulator
CLM98_RS15715	COG1309	transcriptional regulator
CLM98_RS15740	COG0735	belongs to the Fur family
CLM98_RS15745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLM98_RS15770	COG4452	Inner membrane protein CreD
CLM98_RS15780	COG2205	protein histidine kinase activity
CLM98_RS15785	COG0745	RESPONSE REGULATOR receiver
CLM98_RS15790	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CLM98_RS15800	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CLM98_RS15835	COG2198	Histidine kinase
CLM98_RS15835	COG0643	Histidine kinase
CLM98_RS15840	COG0840	transmembrane signaling receptor activity
CLM98_RS15845	COG0835	chemotaxis
CLM98_RS15850	COG2199	diguanylate cyclase activity
CLM98_RS15850	COG2200	EAL domain
CLM98_RS15850	COG2202	Pas domain
CLM98_RS15855	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CLM98_RS15860	COG2201	protein-glutamate methylesterase activity
CLM98_RS15865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLM98_RS15870	COG3590	peptidase
CLM98_RS15880	COG0588	phosphoglycerate mutase activity
CLM98_RS15885	COG1515	deoxyribonuclease V activity
CLM98_RS15895	COG1741	Belongs to the pirin family
CLM98_RS15910	COG1741	Belongs to the pirin family
CLM98_RS15915	COG1966	Carbon starvation protein
CLM98_RS15920	COG2879	small protein
CLM98_RS15985	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CLM98_RS15990	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CLM98_RS15995	COG2080	2 iron, 2 sulfur cluster binding
CLM98_RS16005	COG5001	Diguanylate cyclase
CLM98_RS16005	COG4251	negative regulation of phosphorylation
CLM98_RS16005	COG3706	GGDEF domain
CLM98_RS16005	COG2203	Gaf domain
CLM98_RS16045	COG0629	single-stranded DNA binding
CLM98_RS16050	COG0142	geranyltranstransferase activity
CLM98_RS16065	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CLM98_RS16080	COG0527	aspartate kinase activity
CLM98_RS16085	COG0384	phenazine biosynthesis protein PhzF
CLM98_RS16090	COG0384	phenazine biosynthesis protein PhzF
CLM98_RS16100	COG1764	response to oxidative stress
CLM98_RS16105	COG0540	Belongs to the ATCase OTCase family
CLM98_RS16110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CLM98_RS16115	COG1678	Uncharacterized ACR, COG1678
CLM98_RS16125	COG0519	Catalyzes the synthesis of GMP from XMP
CLM98_RS16135	COG5297	Belongs to the glycosyl hydrolase family 6
CLM98_RS16150	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CLM98_RS16165	COG0739	heme binding
CLM98_RS16185	COG0693	protein deglycase activity
CLM98_RS16195	COG1959	2 iron, 2 sulfur cluster binding
CLM98_RS16200	COG0719	Fe-S assembly protein
CLM98_RS16205	COG0396	ATPase activity
CLM98_RS16210	COG0719	Fe-S assembly protein
CLM98_RS16215	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLM98_RS16225	COG2146	nitrite reductase [NAD(P)H] activity
CLM98_RS16230	COG4774	siderophore transport
CLM98_RS16235	COG3128	pkhd-type hydroxylase
CLM98_RS16260	COG1477	protein flavinylation
CLM98_RS16265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CLM98_RS16280	COG1555	photosystem II stabilization
CLM98_RS16285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLM98_RS16295	COG3178	'Phosphotransferase
CLM98_RS16300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CLM98_RS16310	COG0628	permease
CLM98_RS16320	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CLM98_RS16330	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CLM98_RS16350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLM98_RS16355	COG0271	Belongs to the BolA IbaG family
CLM98_RS16365	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CLM98_RS16375	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CLM98_RS16380	COG1137	ATPase activity
CLM98_RS16395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLM98_RS16400	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CLM98_RS16405	COG1660	Displays ATPase and GTPase activities
CLM98_RS16415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLM98_RS16420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLM98_RS16430	COG2239	Acts as a magnesium transporter
CLM98_RS16445	COG1294	oxidase, subunit
CLM98_RS16450	COG1271	oxidase subunit
CLM98_RS16460	COG1113	amino acid transport
CLM98_RS16490	COG2197	response regulator
CLM98_RS16495	COG0531	amino acid
CLM98_RS16530	COG1234	tRNA 3'-trailer cleavage
CLM98_RS16570	COG2814	Major facilitator Superfamily
CLM98_RS16580	COG0754	glutathionylspermidine amidase activity
CLM98_RS16605	COG1842	Phage shock protein A
CLM98_RS16615	COG0259	pyridoxamine-phosphate oxidase activity
CLM98_RS16620	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLM98_RS16625	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CLM98_RS16635	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CLM98_RS16710	COG2814	Major facilitator Superfamily
CLM98_RS16730	COG0784	Response regulator, receiver
CLM98_RS16730	COG2198	Histidine kinase
CLM98_RS16730	COG2205	protein histidine kinase activity
CLM98_RS16735	COG2353	YceI-like domain
CLM98_RS16755	COG1760	l-serine dehydratase
CLM98_RS16770	COG0460	homoserine dehydrogenase
CLM98_RS16770	COG0527	aspartate kinase activity
CLM98_RS16775	COG0626	cystathionine gamma-synthase activity
CLM98_RS16780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CLM98_RS16785	COG0739	heme binding
CLM98_RS16790	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CLM98_RS16795	COG1272	protein, Hemolysin III
CLM98_RS16800	COG2982	Protein involved in outer membrane biogenesis
CLM98_RS16805	COG0516	GMP reductase activity
CLM98_RS16805	COG0517	IMP dehydrogenase activity
CLM98_RS16810	COG0463	Glycosyl transferase, family 2
CLM98_RS16815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLM98_RS16820	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CLM98_RS16830	COG4771	TonB-dependent receptor
CLM98_RS16840	COG1309	transcriptional regulator
CLM98_RS16850	COG1960	acyl-CoA dehydrogenase activity
CLM98_RS16875	COG0509	glycine decarboxylation via glycine cleavage system
CLM98_RS16880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CLM98_RS16895	COG1742	UPF0060 membrane protein
CLM98_RS16900	COG3956	TIGRFAM MazG family protein
CLM98_RS16910	COG0494	nUDIX hydrolase
CLM98_RS16920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CLM98_RS16925	COG0837	glucose binding
CLM98_RS16940	COG1388	LysM domain
CLM98_RS16940	COG3858	chitin binding
CLM98_RS16955	COG1472	Belongs to the glycosyl hydrolase 3 family
CLM98_RS16970	COG0531	amino acid
CLM98_RS16980	COG1486	melibiose metabolic process
CLM98_RS16990	COG3537	Alpha-1,2-mannosidase
CLM98_RS17030	COG3142	Participates in the control of copper homeostasis
CLM98_RS17035	COG1446	asparaginase
CLM98_RS17070	COG0784	Response regulator, receiver
CLM98_RS17070	COG0643	Histidine kinase
CLM98_RS17070	COG2198	Histidine kinase
CLM98_RS17075	COG0840	transmembrane signaling receptor activity
CLM98_RS17080	COG0835	chemotaxis
CLM98_RS17095	COG0189	ligase activity
CLM98_RS17105	COG1397	ADP-ribosylglycohydrolase
CLM98_RS17115	COG1199	ATP-dependent helicase activity
CLM98_RS17125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLM98_RS17130	COG1215	transferase activity, transferring glycosyl groups
CLM98_RS17150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLM98_RS17160	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CLM98_RS17165	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CLM98_RS17170	COG0535	radical SAM domain protein
CLM98_RS17175	COG0535	radical SAM domain protein
CLM98_RS17190	COG0837	glucose binding
CLM98_RS17205	COG1643	Atp-dependent helicase
CLM98_RS17210	COG0783	Belongs to the Dps family
CLM98_RS17220	COG0514	ATP-dependent DNA helicase (RecQ)
CLM98_RS17255	COG0840	transmembrane signaling receptor activity
CLM98_RS17275	COG3920	Histidine kinase
CLM98_RS17280	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CLM98_RS17290	COG0602	queuosine metabolic process
CLM98_RS17300	COG2885	chlorophyll binding
CLM98_RS17305	COG0823	Involved in the tonB-independent uptake of proteins
CLM98_RS17315	COG0848	biopolymer transport protein
CLM98_RS17325	COG0824	Thioesterase
CLM98_RS17330	COG2255	four-way junction helicase activity
CLM98_RS17340	COG3158	transport of potassium into the cell
CLM98_RS17345	COG0632	four-way junction helicase activity
CLM98_RS17350	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CLM98_RS17355	COG0217	transcriptional regulatory protein
CLM98_RS17370	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CLM98_RS17385	COG0477	Major facilitator Superfamily
CLM98_RS17430	COG0488	(ABC) transporter
CLM98_RS17470	COG4651	solute:proton antiporter activity
CLM98_RS17470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CLM98_RS17495	COG4772	TonB-dependent receptor
CLM98_RS17505	COG4264	IucA IucC family
CLM98_RS17520	COG0019	diaminopimelate decarboxylase activity
CLM98_RS17545	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CLM98_RS17555	COG1492	cobalamin metabolic process
CLM98_RS17565	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CLM98_RS17585	COG4206	TonB-dependent receptor
CLM98_RS17590	COG0542	response to heat
CLM98_RS17595	COG1116	anion transmembrane transporter activity
CLM98_RS17600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM98_RS17605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLM98_RS17610	COG0667	Aldo Keto reductase
CLM98_RS17615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLM98_RS17620	COG4771	TonB-dependent receptor
CLM98_RS17625	COG2827	Endonuclease containing a URI domain
CLM98_RS17670	COG1877	trehalose-phosphatase activity
CLM98_RS17675	COG3387	PFAM Glycoside hydrolase 15-related
CLM98_RS17695	COG0840	transmembrane signaling receptor activity
CLM98_RS17700	COG3011	Protein conserved in bacteria
CLM98_RS17715	COG0564	pseudouridine synthase activity
CLM98_RS17720	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLM98_RS17730	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CLM98_RS17730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLM98_RS17770	COG2369	cell adhesion
CLM98_RS17795	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CLM98_RS17800	COG0045	succinate-CoA ligase (ADP-forming) activity
CLM98_RS17820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLM98_RS17855	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CLM98_RS17860	COG0237	dephospho-CoA kinase activity
CLM98_RS17890	COG5002	protein histidine kinase activity
CLM98_RS17895	COG0745	RESPONSE REGULATOR receiver
CLM98_RS17980	COG2003	Belongs to the UPF0758 family
CLM98_RS18005	COG0784	Response regulator, receiver
CLM98_RS18005	COG4191	Histidine kinase
CLM98_RS18010	COG4191	Histidine kinase
CLM98_RS18010	COG0784	Response regulator, receiver
CLM98_RS18140	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CLM98_RS18170	COG2022	thiamine diphosphate biosynthetic process
CLM98_RS18180	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CLM98_RS18185	COG3273	potassium ion transport
CLM98_RS18185	COG0471	metal ion transport
CLM98_RS18210	COG1970	mechanosensitive ion channel activity
CLM98_RS18230	COG3250	beta-galactosidase activity
CLM98_RS18235	COG4948	Mandelate Racemase Muconate Lactonizing
CLM98_RS18250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLM98_RS18260	COG0308	aminopeptidase N
CLM98_RS18325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM98_RS18335	COG0529	Catalyzes the synthesis of activated sulfate
CLM98_RS18335	COG2895	sulfate adenylyltransferase (ATP) activity
CLM98_RS18340	COG0175	sulfate reduction
CLM98_RS18345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CLM98_RS18350	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLM98_RS18355	COG0175	sulfate reduction
CLM98_RS18375	COG0784	Response regulator, receiver
CLM98_RS18375	COG2198	Histidine kinase
CLM98_RS18375	COG2205	protein histidine kinase activity
CLM98_RS18395	COG1648	precorrin-2 dehydrogenase activity
CLM98_RS18395	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CLM98_RS18410	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CLM98_RS18415	COG3588	fructose-bisphosphate aldolase
CLM98_RS18430	COG0469	pyruvate kinase activity
CLM98_RS18440	COG0126	phosphoglycerate kinase activity
CLM98_RS18465	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CLM98_RS18475	COG3047	cAMP biosynthetic process
CLM98_RS18480	COG3047	cAMP biosynthetic process
CLM98_RS18490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLM98_RS18490	COG3453	Protein conserved in bacteria
CLM98_RS18495	COG0725	ABC transporter, periplasmic molybdate-binding protein
CLM98_RS18500	COG4149	molybdate abc transporter
CLM98_RS18505	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CLM98_RS18540	COG1376	ErfK ybiS ycfS ynhG family protein
CLM98_RS18545	COG0739	heme binding
CLM98_RS18555	COG4773	Receptor
CLM98_RS18560	COG0596	Alpha beta hydrolase
CLM98_RS18565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CLM98_RS18570	COG1301	dicarboxylic acid transport
CLM98_RS18585	COG2304	oxidoreductase activity
CLM98_RS18605	COG0714	Associated with various cellular activities
CLM98_RS18640	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CLM98_RS18665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLM98_RS18675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLM98_RS18685	COG0194	GDP metabolic process
CLM98_RS18690	COG1561	YicC-like family, N-terminal region
CLM98_RS18695	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CLM98_RS18705	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CLM98_RS18710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLM98_RS18725	COG0006	proline dipeptidase activity
CLM98_RS18735	COG0006	proline dipeptidase activity
CLM98_RS18740	COG3079	Belongs to the UPF0149 family
CLM98_RS18760	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CLM98_RS18770	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CLM98_RS18780	COG2912	Transglutaminase-like superfamily
CLM98_RS18785	COG1773	rubredoxin
CLM98_RS18790	COG0352	thiamine-phosphate diphosphorylase activity
CLM98_RS18805	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CLM98_RS18820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLM98_RS18850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLM98_RS18855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLM98_RS18865	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS18875	COG0671	phosphoesterase, PA-phosphatase related
CLM98_RS18880	COG3781	membrane
CLM98_RS18890	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLM98_RS18895	COG0563	adenylate kinase activity
CLM98_RS18910	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CLM98_RS18920	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CLM98_RS18940	COG3710	Transcriptional regulator
CLM98_RS18945	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CLM98_RS18960	COG0840	transmembrane signaling receptor activity
CLM98_RS18965	COG0405	Gamma-glutamyltransferase
CLM98_RS18970	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CLM98_RS18990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLM98_RS18995	COG0473	3-isopropylmalate dehydrogenase activity
CLM98_RS19000	COG0066	3-isopropylmalate dehydratase activity
CLM98_RS19005	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLM98_RS19025	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CLM98_RS19030	COG1538	Outer membrane efflux protein
CLM98_RS19035	COG1519	Transferase
CLM98_RS19040	COG1560	Kdo2-lipid A biosynthetic process
CLM98_RS19065	COG0280	phosphate acetyltransferase
CLM98_RS19065	COG0281	malic enzyme
CLM98_RS19070	COG1301	dicarboxylic acid transport
CLM98_RS19095	COG0583	DNA-binding transcription factor activity
CLM98_RS19100	COG0667	Aldo Keto reductase
CLM98_RS19115	COG2197	response regulator
CLM98_RS19125	COG0642	Histidine kinase
CLM98_RS19145	COG2851	Citrate transporter
CLM98_RS19150	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS19155	COG1609	Transcriptional regulator
CLM98_RS19160	COG2211	Major facilitator Superfamily
CLM98_RS19185	COG1162	GTPase activity
CLM98_RS19215	COG4773	Receptor
CLM98_RS19220	COG0726	polysaccharide deacetylase
CLM98_RS19225	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CLM98_RS19265	COG1307	EDD domain protein, DegV family
CLM98_RS19270	COG0242	peptide deformylase activity
CLM98_RS19300	COG0457	Tetratricopeptide repeat
CLM98_RS19305	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CLM98_RS19310	COG1215	transferase activity, transferring glycosyl groups
CLM98_RS19315	COG1215	transferase activity, transferring glycosyl groups
CLM98_RS19330	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CLM98_RS19385	COG2188	Transcriptional regulator
CLM98_RS19395	COG1450	Type ii and iii secretion system protein
CLM98_RS19410	COG3166	PFAM Fimbrial assembly family protein
CLM98_RS19415	COG3156	type II secretion system protein K
CLM98_RS19420	COG4795	General secretion pathway protein
CLM98_RS19425	COG2165	general secretion pathway protein
CLM98_RS19430	COG4970	Tfp pilus assembly protein FimT
CLM98_RS19435	COG2165	general secretion pathway protein
CLM98_RS19440	COG1459	type II secretion system
CLM98_RS19450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLM98_RS19455	COG1404	Belongs to the peptidase S8 family
CLM98_RS19460	COG5295	Hep Hag repeat protein
CLM98_RS19465	COG1404	Belongs to the peptidase S8 family
CLM98_RS19470	COG5295	Hep Hag repeat protein
CLM98_RS19480	COG0047	phosphoribosylformylglycinamidine synthase activity
CLM98_RS19480	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLM98_RS19490	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CLM98_RS19500	COG4974	Belongs to the 'phage' integrase family
CLM98_RS19515	COG0795	lipopolysaccharide-transporting ATPase activity
CLM98_RS19525	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CLM98_RS19540	COG0525	valine-tRNA ligase activity
CLM98_RS19570	COG1183	phosphatidylcholine synthase activity
CLM98_RS19580	COG0442	prolyl-tRNA aminoacylation
CLM98_RS19595	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CLM98_RS19600	COG1127	ABC transporter
CLM98_RS19605	COG3218	ABC-type transport auxiliary lipoprotein component
CLM98_RS19605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CLM98_RS19640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLM98_RS19645	COG0662	Cupin 2, conserved barrel domain protein
CLM98_RS19645	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CLM98_RS19680	COG2086	electron transfer activity
CLM98_RS19695	COG0546	phosphoglycolate phosphatase activity
CLM98_RS19695	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CLM98_RS19700	COG0277	FAD linked oxidase domain protein
CLM98_RS19715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLM98_RS19745	COG0438	transferase activity, transferring glycosyl groups
CLM98_RS19745	COG1216	Glycosyl transferase, family 2
CLM98_RS19765	COG0626	cystathionine gamma-synthase activity
CLM98_RS19800	COG0625	glutathione transferase activity
CLM98_RS19815	COG0513	Belongs to the DEAD box helicase family
CLM98_RS19825	COG4206	TonB-dependent receptor
CLM98_RS19835	COG0720	synthase
CLM98_RS19845	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CLM98_RS19855	COG1956	GAF domain-containing protein
CLM98_RS19865	COG2819	hydrolase of the alpha beta superfamily
CLM98_RS19880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLM98_RS19885	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLM98_RS19900	COG0339	signal peptide processing
CLM98_RS19955	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CLM98_RS19960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM98_RS19965	COG4591	ABC-type transport system involved in lipoprotein release permease component
CLM98_RS19965	COG1136	(ABC) transporter
CLM98_RS19970	COG1136	(ABC) transporter
CLM98_RS19970	COG0577	efflux transmembrane transporter activity
CLM98_RS19975	COG0577	efflux transmembrane transporter activity
CLM98_RS19990	COG4191	Histidine kinase
CLM98_RS19995	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CLM98_RS20010	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CLM98_RS20015	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CLM98_RS20020	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CLM98_RS20025	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CLM98_RS20030	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLM98_RS20035	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CLM98_RS20045	COG0356	it plays a direct role in the translocation of protons across the membrane
CLM98_RS20065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLM98_RS20075	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLM98_RS20115	COG2011	ABC-type metal ion transport system permease component
CLM98_RS20120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLM98_RS20125	COG0697	spore germination
CLM98_RS20130	COG1666	GTP binding
CLM98_RS20140	COG0784	Response regulator, receiver
CLM98_RS20140	COG5002	protein histidine kinase activity
CLM98_RS20140	COG2198	Histidine kinase
CLM98_RS20165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLM98_RS20170	COG1187	pseudouridine synthase activity
CLM98_RS20175	COG2813	Specifically methylates the guanine in position
CLM98_RS20195	COG2205	protein histidine kinase activity
CLM98_RS20195	COG2202	Pas domain
CLM98_RS20215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLM98_RS20220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM98_RS20280	COG0842	Transport permease protein
CLM98_RS20285	COG1131	(ABC) transporter
CLM98_RS20290	COG0025	NhaP-type Na H and K H
CLM98_RS20300	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CLM98_RS20305	COG1573	uracil-dna glycosylase
CLM98_RS20315	COG3384	dioxygenase
CLM98_RS20325	COG0583	DNA-binding transcription factor activity
CLM98_RS20335	COG0667	Aldo Keto reductase
CLM98_RS20370	COG0531	amino acid
CLM98_RS20385	COG2972	Histidine kinase
CLM98_RS20410	COG3685	Protein conserved in bacteria
CLM98_RS20415	COG3546	catalase activity
CLM98_RS20465	COG1271	oxidase subunit
CLM98_RS20470	COG1294	oxidase, subunit
CLM98_RS20485	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS20490	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLM98_RS20510	COG1132	(ABC) transporter
CLM98_RS20525	COG1063	alcohol dehydrogenase
CLM98_RS20600	COG0251	oxidation-reduction process
CLM98_RS20630	COG0840	transmembrane signaling receptor activity
CLM98_RS20650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CLM98_RS20695	COG0024	Methionine aminopeptidase
CLM98_RS20725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLM98_RS20730	COG1490	D-aminoacyl-tRNA deacylase activity
CLM98_RS20735	COG1560	Kdo2-lipid A biosynthetic process
CLM98_RS20790	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CLM98_RS20790	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLM98_RS20795	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLM98_RS20800	COG0242	peptide deformylase activity
CLM98_RS20805	COG1652	LysM domain
CLM98_RS20810	COG0758	DNA mediated transformation
CLM98_RS20815	COG2922	Belongs to the Smg family
CLM98_RS20830	COG1754	DNA topoisomerase type I activity
CLM98_RS20830	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLM98_RS20835	COG0009	L-threonylcarbamoyladenylate synthase
CLM98_RS20850	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS20860	COG0616	signal peptide processing
CLM98_RS20865	COG0534	Mate efflux family protein
CLM98_RS20885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLM98_RS20890	COG0625	glutathione transferase activity
CLM98_RS20905	COG1252	NADH dehydrogenase
CLM98_RS20910	COG2860	membrane
CLM98_RS20915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLM98_RS20920	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CLM98_RS20925	COG3437	response regulator, receiver
CLM98_RS20930	COG2177	Part of the ABC transporter FtsEX involved in
CLM98_RS20935	COG2884	Cell division ATP-binding protein ftsE
CLM98_RS20940	COG0513	Belongs to the DEAD box helicase family
CLM98_RS20945	COG3118	belongs to the thioredoxin family
CLM98_RS20950	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CLM98_RS20960	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CLM98_RS20965	COG0583	DNA-binding transcription factor activity
CLM98_RS21010	COG1518	maintenance of DNA repeat elements
CLM98_RS21015	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CLM98_RS21025	COG1652	LysM domain
CLM98_RS21030	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CLM98_RS21030	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CLM98_RS21035	COG1473	amidohydrolase
CLM98_RS21040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM98_RS21045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM98_RS21055	COG5383	Protein conserved in bacteria
CLM98_RS21110	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CLM98_RS21115	COG3023	N-Acetylmuramoyl-L-alanine amidase
CLM98_RS21125	COG4948	Mandelate Racemase Muconate Lactonizing
CLM98_RS21135	COG0531	amino acid
CLM98_RS21150	COG4682	membrane
CLM98_RS21155	COG2133	pyrroloquinoline quinone binding
CLM98_RS21165	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CLM98_RS21170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CLM98_RS21180	COG1610	YqeY-like protein
CLM98_RS21190	COG1295	ribonuclease BN
CLM98_RS21195	COG0358	DNA primase activity
CLM98_RS21210	COG0109	protoheme IX farnesyltransferase activity
CLM98_RS21240	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CLM98_RS21255	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CLM98_RS21300	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CLM98_RS21305	COG0739	heme binding
CLM98_RS21310	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CLM98_RS21320	COG2211	Major facilitator Superfamily
CLM98_RS21325	COG0708	Exodeoxyribonuclease III
CLM98_RS21330	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CLM98_RS21340	COG1192	Involved in chromosome partitioning
CLM98_RS21345	COG1475	DNA binding
CLM98_RS21365	COG0463	Glycosyl transferase, family 2
CLM98_RS21385	COG0756	dUTP diphosphatase activity
CLM98_RS21390	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLM98_RS21395	COG2003	Belongs to the UPF0758 family
CLM98_RS21400	COG0018	arginyl-trna synthetase
CLM98_RS21415	COG4221	oxidoreductase activity
CLM98_RS21420	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CLM98_RS21420	COG2755	lipolytic protein G-D-S-L family
CLM98_RS21430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLM98_RS21435	COG1166	arginine decarboxylase activity
CLM98_RS21440	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CLM98_RS21485	COG0606	chelatase, subunit chli
CLM98_RS21500	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CLM98_RS21535	COG1690	Belongs to the RtcB family
CLM98_RS21570	COG1090	epimerase
CLM98_RS21580	COG0642	Histidine kinase
CLM98_RS21610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLM98_RS21635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLM98_RS21640	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CLM98_RS21655	COG0753	catalase activity
CLM98_RS21670	COG2197	response regulator
CLM98_RS21675	COG4585	Histidine kinase
CLM98_RS21680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM98_RS21685	COG1136	(ABC) transporter
CLM98_RS21710	COG0697	spore germination
CLM98_RS21730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLM98_RS21735	COG0180	Tryptophanyl-tRNA synthetase
CLM98_RS21740	COG3237	CsbD-like
CLM98_RS21785	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLM98_RS21800	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CLM98_RS21850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLM98_RS21880	COG1199	ATP-dependent helicase activity
CLM98_RS21895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLM98_RS21955	COG0625	glutathione transferase activity
CLM98_RS21995	COG4555	ABC transporter
CLM98_RS22005	COG1476	TRANSCRIPTIONal
CLM98_RS22050	COG0633	Ferredoxin
CLM98_RS22050	COG0543	2 iron, 2 sulfur cluster binding
CLM98_RS22055	COG1131	(ABC) transporter
CLM98_RS22060	COG0842	Transport permease protein
CLM98_RS22070	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLM98_RS22105	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLM98_RS22110	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLM98_RS22125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLM98_RS22125	COG0045	succinate-CoA ligase (ADP-forming) activity
CLM98_RS22125	COG1042	CoA-binding domain protein
CLM98_RS22130	COG2239	Acts as a magnesium transporter
CLM98_RS22145	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CLM98_RS22150	COG3387	PFAM Glycoside hydrolase 15-related
CLM98_RS22165	COG3100	YcgL domain-containing protein
CLM98_RS22170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLM98_RS22180	COG0463	Glycosyl transferase, family 2
CLM98_RS22200	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS22235	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLM98_RS22250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLM98_RS22280	COG0823	Involved in the tonB-independent uptake of proteins
CLM98_RS22280	COG1506	peptidase
CLM98_RS22280	COG4946	Tricorn protease homolog
CLM98_RS22300	COG0408	coproporphyrinogen oxidase activity
CLM98_RS22340	COG2815	serine threonine protein kinase
CLM98_RS22340	COG0515	serine threonine protein kinase
CLM98_RS22345	COG0631	protein serine/threonine phosphatase activity
CLM98_RS22515	COG0210	DNA helicase
CLM98_RS22530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLM98_RS22535	COG0583	DNA-binding transcription factor activity
CLM98_RS22540	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLM98_RS22555	COG2159	amidohydrolase
CLM98_RS22575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM98_RS22595	COG0357	Ribosomal RNA small subunit methyltransferase G
CLM98_RS22600	COG3540	Alkaline phosphatase
CLM98_RS22610	COG2091	lysine biosynthetic process via aminoadipic acid
CLM98_RS22625	COG0708	Exodeoxyribonuclease III
CLM98_RS22630	COG1940	carbohydrate kinase activity
CLM98_RS22630	COG1846	Transcriptional regulator
CLM98_RS22640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLM98_RS22650	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLM98_RS22655	COG3162	membrane
CLM98_RS22665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLM98_RS22695	COG3507	Belongs to the glycosyl hydrolase 43 family
CLM98_RS22715	COG1028	Short-chain dehydrogenase reductase Sdr
CLM98_RS22720	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLM98_RS22730	COG4948	Mandelate Racemase Muconate Lactonizing
CLM98_RS22740	COG3254	rhamnose metabolic process
CLM98_RS22745	COG0738	Major facilitator superfamily
CLM98_RS22750	COG1414	Transcriptional regulator
CLM98_RS22755	COG1971	Probably functions as a manganese efflux pump
CLM98_RS22760	COG2205	protein histidine kinase activity
CLM98_RS22775	COG3459	Glycosyltransferase 36 associated
CLM98_RS22780	COG2211	Major facilitator Superfamily
CLM98_RS22785	COG3265	gluconokinase activity
CLM98_RS22795	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLM98_RS22815	COG2911	Protein conserved in bacteria
CLM98_RS22820	COG0729	surface antigen
CLM98_RS22855	COG0752	glycyl-tRNA synthetase alpha subunit
CLM98_RS22860	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLM98_RS22875	COG0519	Catalyzes the synthesis of GMP from XMP
CLM98_RS22875	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CLM98_RS22885	COG0805	protein transport
CLM98_RS22890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLM98_RS22895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLM98_RS22905	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CLM98_RS22930	COG2974	May be involved in recombination
CLM98_RS22935	COG0037	tRNA processing
CLM98_RS22945	COG2115	Belongs to the xylose isomerase family
CLM98_RS22955	COG3661	Belongs to the glycosyl hydrolase 67 family
CLM98_RS22965	COG4948	Mandelate Racemase Muconate Lactonizing
CLM98_RS22975	COG1472	Belongs to the glycosyl hydrolase 3 family
CLM98_RS22980	COG0246	Mannitol dehydrogenase
CLM98_RS23060	COG3386	PFAM SMP-30 Gluconolaconase
CLM98_RS23070	COG3250	beta-galactosidase activity
CLM98_RS23075	COG1904	glucuronate isomerase
CLM98_RS23080	COG3693	PFAM glycoside hydrolase, family 10
CLM98_RS23090	COG3693	PFAM glycoside hydrolase, family 10
CLM98_RS23105	COG2211	Major facilitator Superfamily
CLM98_RS23170	COG2937	Belongs to the GPAT DAPAT family
CLM98_RS23205	COG0284	orotidine-5'-phosphate decarboxylase activity
CLM98_RS23210	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CLM98_RS23220	COG3132	Protein of unknown function, DUF480
CLM98_RS23235	COG0210	DNA helicase
CLM98_RS23240	COG1435	thymidine kinase activity
CLM98_RS23250	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CLM98_RS23260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CLM98_RS23315	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CLM98_RS23405	COG1199	ATP-dependent helicase activity
CLM98_RS23415	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CLM98_RS23425	COG0745	RESPONSE REGULATOR receiver
CLM98_RS23505	COG1525	nuclease
CLM98_RS23565	COG1475	DNA binding
CLM98_RS23600	COG0629	single-stranded DNA binding
CLM98_RS23660	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLM98_RS23760	COG4232	protein-disulfide reductase activity
CLM98_RS23865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM98_RS23870	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM98_RS23885	COG0010	Belongs to the arginase family
CLM98_RS23940	COG2132	Multicopper oxidase
CLM98_RS23970	COG0653	protein targeting
CLM98_RS23995	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CLM98_RS24010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLM98_RS24020	COG0431	NADPH-dependent FMN reductase
CLM98_RS24025	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CLM98_RS24070	COG4644	lycopene metabolic process
CLM98_RS24095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLM98_RS24575	COG3504	Conjugal transfer protein
CLM98_RS24580	COG2948	multi-organism process
CLM98_RS24750	COG3012	SEC-C Motif Domain Protein
CLM98_RS24750	COG3318	Belongs to the UPF0149 family
CLM98_RS24780	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CLM98_RS24825	COG2951	lytic endotransglycosylase activity
CLM98_RS24830	COG4644	lycopene metabolic process
CLM98_RS24970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CLM98_RS25000	COG1192	Involved in chromosome partitioning
CLM98_RS25020	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CLM98_RS25040	COG3012	SEC-C Motif Domain Protein
CLM98_RS25040	COG3318	Belongs to the UPF0149 family