locus-tag	class	description
AMD17_RS00025	COG0592	DNA-directed DNA polymerase activity
AMD17_RS00050	COG0187	DNA topoisomerase II activity
AMD17_RS00070	COG0501	Belongs to the peptidase M48B family
AMD17_RS00295	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AMD17_RS00340	COG0493	'glutamate synthase
AMD17_RS00355	COG0070	glutamate synthase
AMD17_RS00355	COG0067	glutamate synthase
AMD17_RS00355	COG0069	glutamate synthase activity
AMD17_RS00365	COG0070	glutamate synthase
AMD17_RS00365	COG0069	glutamate synthase activity
AMD17_RS00365	COG0067	glutamate synthase
AMD17_RS00465	COG0367	asparagine synthase
AMD17_RS00485	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AMD17_RS00495	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AMD17_RS00500	COG0187	DNA topoisomerase II activity
AMD17_RS00510	COG0501	Belongs to the peptidase M48B family
AMD17_RS00540	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AMD17_RS00550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMD17_RS00595	COG0793	Belongs to the peptidase S41A family
AMD17_RS00600	COG4942	peptidase
AMD17_RS00610	COG2234	aminopeptidase activity
AMD17_RS00620	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AMD17_RS00625	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AMD17_RS00630	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AMD17_RS00635	COG1064	alcohol dehydrogenase
AMD17_RS00640	COG0493	'glutamate synthase
AMD17_RS00645	COG0070	glutamate synthase
AMD17_RS00645	COG0069	glutamate synthase activity
AMD17_RS00645	COG0067	glutamate synthase
AMD17_RS00690	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMD17_RS00705	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AMD17_RS00710	COG0438	transferase activity, transferring glycosyl groups
AMD17_RS00710	COG0297	glycogen (starch) synthase activity
AMD17_RS00730	COG0367	asparagine synthase
AMD17_RS00760	COG1132	(ABC) transporter
AMD17_RS00790	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AMD17_RS00870	COG1205	dead DEAH box helicase
AMD17_RS00870	COG1111	helicase
AMD17_RS00875	COG1272	protein, Hemolysin III
AMD17_RS00890	COG0300	oxidoreductase activity
AMD17_RS00895	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS00915	COG2249	NAD(P)H dehydrogenase (quinone) activity
AMD17_RS00975	COG3237	CsbD-like
AMD17_RS01025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMD17_RS01035	COG0477	Major facilitator Superfamily
AMD17_RS01075	COG0714	Associated with various cellular activities
AMD17_RS01105	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AMD17_RS01115	COG4772	TonB-dependent receptor
AMD17_RS01125	COG0662	Cupin 2, conserved barrel domain protein
AMD17_RS01130	COG1012	belongs to the aldehyde dehydrogenase family
AMD17_RS01155	COG1304	FMN binding
AMD17_RS01170	COG4585	Histidine kinase
AMD17_RS01175	COG2197	response regulator
AMD17_RS01195	COG3710	Transcriptional regulator
AMD17_RS01200	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMD17_RS01270	COG2801	Transposase and inactivated derivatives
AMD17_RS01275	COG0366	Alpha amylase catalytic
AMD17_RS01280	COG0366	Alpha amylase catalytic
AMD17_RS01285	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AMD17_RS01305	COG0657	acetylesterase activity
AMD17_RS01305	COG2755	lipolytic protein G-D-S-L family
AMD17_RS01315	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AMD17_RS01330	COG3507	Belongs to the glycosyl hydrolase 43 family
AMD17_RS01335	COG1609	Transcriptional regulator
AMD17_RS01340	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AMD17_RS01345	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS01355	COG2755	lipolytic protein G-D-S-L family
AMD17_RS01370	COG3186	Phenylalanine-4-hydroxylase
AMD17_RS01375	COG1522	sequence-specific DNA binding
AMD17_RS01385	COG1752	Esterase of the alpha-beta hydrolase superfamily
AMD17_RS01395	COG1119	ATPase activity
AMD17_RS01410	COG1125	glycine betaine transport
AMD17_RS01425	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMD17_RS01445	COG1396	sequence-specific DNA binding
AMD17_RS01470	COG0489	protein tyrosine kinase activity
AMD17_RS01475	COG2062	phosphohistidine phosphatase, SixA
AMD17_RS01485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMD17_RS01530	COG1968	undecaprenyl-diphosphatase activity
AMD17_RS01535	COG0174	glutamine synthetase
AMD17_RS01540	COG0347	Belongs to the P(II) protein family
AMD17_RS01545	COG0004	ammonium transporteR
AMD17_RS01550	COG3852	Histidine kinase
AMD17_RS01555	COG2204	response regulator
AMD17_RS01560	COG2032	superoxide dismutase activity
AMD17_RS01565	COG2032	superoxide dismutase activity
AMD17_RS01570	COG0346	lactoylglutathione lyase activity
AMD17_RS01580	COG0183	Belongs to the thiolase family
AMD17_RS01615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMD17_RS01620	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AMD17_RS01625	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AMD17_RS01635	COG0028	Belongs to the TPP enzyme family
AMD17_RS01640	COG2205	protein histidine kinase activity
AMD17_RS01665	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AMD17_RS01680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMD17_RS01690	COG0596	Alpha beta hydrolase
AMD17_RS01695	COG0727	PFAM Uncharacterised protein family (UPF0153)
AMD17_RS01700	COG0318	PFAM AMP-dependent synthetase and ligase
AMD17_RS01705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMD17_RS01720	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMD17_RS01730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMD17_RS01740	COG0564	pseudouridine synthase activity
AMD17_RS01765	COG0339	signal peptide processing
AMD17_RS01795	COG0475	glutathione-regulated potassium exporter activity
AMD17_RS01800	COG0583	DNA-binding transcription factor activity
AMD17_RS01805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AMD17_RS01810	COG2224	Isocitrate lyase
AMD17_RS01840	COG4770	biotin carboxylase activity
AMD17_RS01845	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMD17_RS01850	COG1960	acyl-CoA dehydrogenase activity
AMD17_RS01905	COG0523	cobalamin synthesis protein
AMD17_RS01920	COG0697	spore germination
AMD17_RS01930	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AMD17_RS01935	COG1846	Transcriptional regulator
AMD17_RS01940	COG1764	response to oxidative stress
AMD17_RS01970	COG2130	NADP-dependent
AMD17_RS01985	COG1187	pseudouridine synthase activity
AMD17_RS02000	COG1643	Atp-dependent helicase
AMD17_RS02010	COG4807	Protein conserved in bacteria
AMD17_RS02015	COG2351	hydroxyisourate hydrolase activity
AMD17_RS02020	COG2072	flavoprotein involved in K transport
AMD17_RS02040	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AMD17_RS02075	COG1957	nucleoside hydrolase
AMD17_RS02085	COG2252	PERMEase
AMD17_RS02110	COG0084	hydrolase, TatD family'
AMD17_RS02125	COG0583	DNA-binding transcription factor activity
AMD17_RS02130	COG2814	Major facilitator Superfamily
AMD17_RS02145	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AMD17_RS02150	COG1902	pentaerythritol trinitrate reductase activity
AMD17_RS02170	COG0745	RESPONSE REGULATOR receiver
AMD17_RS02175	COG2205	protein histidine kinase activity
AMD17_RS02180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMD17_RS02200	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AMD17_RS02205	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AMD17_RS02210	COG0583	DNA-binding transcription factor activity
AMD17_RS02240	COG0702	epimerase
AMD17_RS02245	COG1733	regulation of RNA biosynthetic process
AMD17_RS02270	COG2801	Transposase and inactivated derivatives
AMD17_RS02285	COG0129	dihydroxy-acid dehydratase activity
AMD17_RS02305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AMD17_RS02360	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AMD17_RS02365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AMD17_RS02390	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AMD17_RS02395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AMD17_RS02405	COG3485	protocatechuate 3,4-dioxygenase
AMD17_RS02410	COG3485	protocatechuate 3,4-dioxygenase
AMD17_RS02420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMD17_RS02425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AMD17_RS02435	COG1414	Transcriptional regulator
AMD17_RS02445	COG0657	acetylesterase activity
AMD17_RS02455	COG0445	tRNA wobble uridine modification
AMD17_RS02465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMD17_RS02495	COG2267	carboxylic ester hydrolase activity
AMD17_RS02505	COG0156	8-amino-7-oxononanoate synthase activity
AMD17_RS02510	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AMD17_RS02515	COG1040	competence protein
AMD17_RS02520	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AMD17_RS02595	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMD17_RS02665	COG1511	domain protein
AMD17_RS02665	COG3264	Mechanosensitive ion channel
AMD17_RS02670	COG1368	sulfuric ester hydrolase activity
AMD17_RS02675	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMD17_RS02680	COG2354	Protein conserved in bacteria
AMD17_RS02690	COG0297	glycogen (starch) synthase activity
AMD17_RS02695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AMD17_RS02700	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AMD17_RS02725	COG0702	epimerase
AMD17_RS02730	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS02765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMD17_RS02770	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS02780	COG0513	Belongs to the DEAD box helicase family
AMD17_RS02800	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AMD17_RS02810	COG3483	tryptophan 2,3-dioxygenase activity
AMD17_RS02815	COG3104	oligopeptide transport
AMD17_RS02835	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AMD17_RS02850	COG1320	monovalent cation:proton antiporter activity
AMD17_RS02855	COG2212	antiporter activity
AMD17_RS02865	COG0651	ATP synthesis coupled electron transport
AMD17_RS02870	COG1006	Multisubunit Na H antiporter MnhC subunit
AMD17_RS02875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AMD17_RS02875	COG2111	Na H antiporter
AMD17_RS02895	COG3179	chitinase
AMD17_RS02915	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AMD17_RS02920	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AMD17_RS02935	COG0456	acetyltransferase
AMD17_RS02940	COG1597	lipid kinase activity
AMD17_RS02965	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMD17_RS02970	COG0134	indole-3-glycerol-phosphate synthase activity
AMD17_RS02980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMD17_RS02985	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AMD17_RS02995	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AMD17_RS03005	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AMD17_RS03020	COG1051	belongs to the nudix hydrolase family
AMD17_RS03060	COG0316	Belongs to the HesB IscA family
AMD17_RS03085	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AMD17_RS03105	COG2814	Major facilitator Superfamily
AMD17_RS03110	COG0583	DNA-binding transcription factor activity
AMD17_RS03115	COG2814	Major facilitator Superfamily
AMD17_RS03120	COG1289	transmembrane transporter activity
AMD17_RS03130	COG0151	Belongs to the GarS family
AMD17_RS03140	COG0138	bifunctional purine biosynthesis protein purh
AMD17_RS03145	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMD17_RS03150	COG2267	carboxylic ester hydrolase activity
AMD17_RS03155	COG0671	phosphoesterase, PA-phosphatase related
AMD17_RS03155	COG2453	phosphatase
AMD17_RS03180	COG4589	Belongs to the CDS family
AMD17_RS03185	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AMD17_RS03210	COG2264	protein methyltransferase activity
AMD17_RS03225	COG0439	Biotin carboxylase
AMD17_RS03235	COG0511	ligase activity, forming carbon-carbon bonds
AMD17_RS03240	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AMD17_RS03250	COG1324	tolerance protein
AMD17_RS03275	COG0300	oxidoreductase activity
AMD17_RS03280	COG2356	endonuclease I
AMD17_RS03290	COG0459	protein refolding
AMD17_RS03305	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMD17_RS03320	COG3386	PFAM SMP-30 Gluconolaconase
AMD17_RS03330	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AMD17_RS03335	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AMD17_RS03355	COG0778	Nitroreductase
AMD17_RS03360	COG2353	YceI-like domain
AMD17_RS03390	COG3052	prosthetic group binding
AMD17_RS03415	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AMD17_RS03425	COG1802	Transcriptional regulator
AMD17_RS03470	COG2801	Transposase and inactivated derivatives
AMD17_RS03480	COG4221	oxidoreductase activity
AMD17_RS03495	COG4221	oxidoreductase activity
AMD17_RS03505	COG0435	Glutathione S-transferase
AMD17_RS03530	COG2409	Drug exporters of the RND superfamily
AMD17_RS03535	COG1506	peptidase
AMD17_RS03535	COG0823	Involved in the tonB-independent uptake of proteins
AMD17_RS03575	COG0697	spore germination
AMD17_RS03590	COG1113	amino acid transport
AMD17_RS03610	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AMD17_RS03645	COG5001	Diguanylate cyclase
AMD17_RS03650	COG0840	transmembrane signaling receptor activity
AMD17_RS03655	COG5297	Belongs to the glycosyl hydrolase family 6
AMD17_RS03655	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AMD17_RS03660	COG0659	secondary active sulfate transmembrane transporter activity
AMD17_RS03680	COG2943	transferase activity, transferring hexosyl groups
AMD17_RS03690	COG3275	phosphorelay sensor kinase activity
AMD17_RS03700	COG0181	hydroxymethylbilane synthase activity
AMD17_RS03725	COG1505	serine-type exopeptidase activity
AMD17_RS03730	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMD17_RS03735	COG0436	Aminotransferase
AMD17_RS03745	COG2832	Protein of unknown function (DUF454)
AMD17_RS03755	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AMD17_RS03765	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AMD17_RS03770	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AMD17_RS03775	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AMD17_RS03800	COG2226	methyltransferase
AMD17_RS03805	COG3300	MHYT domain
AMD17_RS03805	COG5001	Diguanylate cyclase
AMD17_RS03810	COG0308	aminopeptidase N
AMD17_RS03860	COG3284	Transcriptional regulator
AMD17_RS03865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMD17_RS03870	COG1077	Cell shape determining protein MreB Mrl
AMD17_RS03875	COG1792	Involved in formation and maintenance of cell shape
AMD17_RS03890	COG0772	Belongs to the SEDS family
AMD17_RS03900	COG2951	lytic endotransglycosylase activity
AMD17_RS03905	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMD17_RS03915	COG1686	Belongs to the peptidase S11 family
AMD17_RS03925	COG2921	Belongs to the UPF0250 family
AMD17_RS03930	COG0321	lipoyl(octanoyl) transferase activity
AMD17_RS03935	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMD17_RS03950	COG0583	DNA-binding transcription factor activity
AMD17_RS03960	COG1056	cytidyltransferase-related domain
AMD17_RS03960	COG1051	belongs to the nudix hydrolase family
AMD17_RS03995	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AMD17_RS04000	COG0673	inositol 2-dehydrogenase activity
AMD17_RS04005	COG2823	Periplasmic or secreted lipoprotein
AMD17_RS04010	COG4251	negative regulation of phosphorylation
AMD17_RS04015	COG0784	Response regulator, receiver
AMD17_RS04020	COG4191	Histidine kinase
AMD17_RS04025	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AMD17_RS04080	COG1459	type II secretion system
AMD17_RS04145	COG2188	Transcriptional regulator
AMD17_RS04155	COG1609	Transcriptional regulator
AMD17_RS04160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMD17_RS04165	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AMD17_RS04175	COG0617	tRNA 3'-terminal CCA addition
AMD17_RS04180	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AMD17_RS04185	COG1012	belongs to the aldehyde dehydrogenase family
AMD17_RS04190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AMD17_RS04200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMD17_RS04215	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AMD17_RS04220	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AMD17_RS04235	COG2205	protein histidine kinase activity
AMD17_RS04265	COG3791	Glutathione-dependent formaldehyde-activating
AMD17_RS04280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMD17_RS04290	COG0697	spore germination
AMD17_RS04300	COG0488	(ABC) transporter
AMD17_RS04310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMD17_RS04315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AMD17_RS04325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMD17_RS04325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMD17_RS04345	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AMD17_RS04350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMD17_RS04355	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AMD17_RS04375	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AMD17_RS04380	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AMD17_RS04385	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AMD17_RS04390	COG2205	protein histidine kinase activity
AMD17_RS04395	COG0745	RESPONSE REGULATOR receiver
AMD17_RS04410	COG0277	FAD linked oxidase domain protein
AMD17_RS04415	COG1988	membrane-bound metal-dependent
AMD17_RS04420	COG0792	nuclease activity
AMD17_RS04450	COG0275	rRNA processing
AMD17_RS04455	COG3116	cell division
AMD17_RS04465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AMD17_RS04470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AMD17_RS04475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMD17_RS04485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AMD17_RS04490	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMD17_RS04495	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMD17_RS04500	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AMD17_RS04515	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AMD17_RS04525	COG0739	heme binding
AMD17_RS04530	COG0653	protein targeting
AMD17_RS04535	COG0494	nUDIX hydrolase
AMD17_RS04545	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AMD17_RS04555	COG3321	synthase
AMD17_RS04555	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS04555	COG0604	alcohol dehydrogenase
AMD17_RS04575	COG0366	Alpha amylase catalytic
AMD17_RS04605	COG2226	methyltransferase
AMD17_RS04610	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AMD17_RS04620	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AMD17_RS04655	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AMD17_RS04665	COG4106	trans-aconitate 2-methyltransferase activity
AMD17_RS04670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMD17_RS04680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMD17_RS04685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AMD17_RS04690	COG0667	Aldo Keto reductase
AMD17_RS04700	COG4771	TonB-dependent receptor
AMD17_RS04720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMD17_RS04725	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AMD17_RS04735	COG2175	clavaminate synthase activity
AMD17_RS04745	COG4181	ATPase activity
AMD17_RS04760	COG0642	Histidine kinase
AMD17_RS04770	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AMD17_RS04790	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AMD17_RS04795	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AMD17_RS04810	COG3829	transcription factor binding
AMD17_RS04820	COG1116	anion transmembrane transporter activity
AMD17_RS04825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMD17_RS04835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMD17_RS04840	COG0431	NADPH-dependent FMN reductase
AMD17_RS04865	COG0747	negative chemotaxis
AMD17_RS04875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMD17_RS04885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AMD17_RS04890	COG2967	ApaG domain
AMD17_RS04895	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AMD17_RS04900	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AMD17_RS04905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMD17_RS04910	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AMD17_RS04920	COG0123	including yeast histone deacetylase and acetoin utilization protein
AMD17_RS04925	COG2096	Adenosyltransferase
AMD17_RS04935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMD17_RS04940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMD17_RS04970	COG3384	dioxygenase
AMD17_RS04975	COG0583	DNA-binding transcription factor activity
AMD17_RS04990	COG1024	Enoyl-CoA hydratase
AMD17_RS05010	COG3386	PFAM SMP-30 Gluconolaconase
AMD17_RS05020	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AMD17_RS05045	COG0697	spore germination
AMD17_RS05055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMD17_RS05075	COG0784	Response regulator, receiver
AMD17_RS05075	COG2205	protein histidine kinase activity
AMD17_RS05075	COG5002	protein histidine kinase activity
AMD17_RS05080	COG2197	response regulator
AMD17_RS05090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMD17_RS05100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AMD17_RS05105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMD17_RS05110	COG0583	DNA-binding transcription factor activity
AMD17_RS05115	COG3634	alkyl hydroperoxide reductase activity
AMD17_RS05125	COG2890	protein-(glutamine-N5) methyltransferase activity
AMD17_RS05145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMD17_RS05145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMD17_RS05175	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AMD17_RS05205	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AMD17_RS05220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMD17_RS05225	COG1404	Belongs to the peptidase S8 family
AMD17_RS05230	COG1404	Belongs to the peptidase S8 family
AMD17_RS05235	COG1404	Belongs to the peptidase S8 family
AMD17_RS05240	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AMD17_RS05265	COG1295	ribonuclease BN
AMD17_RS05270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMD17_RS05275	COG1254	Belongs to the acylphosphatase family
AMD17_RS05290	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMD17_RS05300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AMD17_RS05305	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AMD17_RS05315	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AMD17_RS05320	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AMD17_RS05330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AMD17_RS05335	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AMD17_RS05340	COG0193	aminoacyl-tRNA hydrolase activity
AMD17_RS05345	COG0012	GTP binding
AMD17_RS05380	COG0250	Participates in transcription elongation, termination and antitermination
AMD17_RS05385	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AMD17_RS05390	COG0081	regulation of translation
AMD17_RS05395	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AMD17_RS05400	COG0222	ribosome binding
AMD17_RS05405	COG0085	RNA polymerase activity
AMD17_RS05410	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AMD17_RS05415	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AMD17_RS05420	COG0049	tRNA binding
AMD17_RS05425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMD17_RS05430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMD17_RS05435	COG0051	transcription antitermination factor activity, RNA binding
AMD17_RS05440	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AMD17_RS05445	COG0088	Forms part of the polypeptide exit tunnel
AMD17_RS05450	COG0089	rRNA binding
AMD17_RS05455	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AMD17_RS05460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AMD17_RS05470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AMD17_RS05475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AMD17_RS05480	COG0255	Belongs to the universal ribosomal protein uL29 family
AMD17_RS05485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AMD17_RS05495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AMD17_RS05500	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AMD17_RS05510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AMD17_RS05515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AMD17_RS05520	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AMD17_RS05530	COG1841	ribosomal large subunit assembly
AMD17_RS05535	COG0200	Binds to the 23S rRNA
AMD17_RS05540	COG0201	protein transport
AMD17_RS05565	COG0203	ribosomal protein L17
AMD17_RS05570	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AMD17_RS05585	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AMD17_RS05595	COG0154	amidase activity
AMD17_RS05605	COG1217	gtp-binding protein TYPA
AMD17_RS05610	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMD17_RS05615	COG0039	L-malate dehydrogenase activity
AMD17_RS05620	COG0625	glutathione transferase activity
AMD17_RS05630	COG1902	pentaerythritol trinitrate reductase activity
AMD17_RS05630	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMD17_RS05635	COG0604	alcohol dehydrogenase
AMD17_RS05660	COG0156	8-amino-7-oxononanoate synthase activity
AMD17_RS05665	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AMD17_RS05670	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AMD17_RS05675	COG4208	sulfate ABC transporter
AMD17_RS05680	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AMD17_RS05690	COG1063	alcohol dehydrogenase
AMD17_RS05720	COG0406	alpha-ribazole phosphatase activity
AMD17_RS05725	COG0285	dihydrofolate synthase activity
AMD17_RS05745	COG2833	Protein of unknown function (DUF455)
AMD17_RS05755	COG3291	Pkd domain containing protein
AMD17_RS05765	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMD17_RS05770	COG0671	phosphoesterase, PA-phosphatase related
AMD17_RS05775	COG0438	transferase activity, transferring glycosyl groups
AMD17_RS05785	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AMD17_RS05800	COG4783	chaperone-mediated protein folding
AMD17_RS05815	COG0473	3-isopropylmalate dehydrogenase activity
AMD17_RS05945	COG2801	Transposase and inactivated derivatives
AMD17_RS05960	COG3852	Histidine kinase
AMD17_RS05970	COG0544	peptidyl-prolyl cis-trans isomerase activity
AMD17_RS05980	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AMD17_RS06010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMD17_RS06020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMD17_RS06030	COG0328	RNA-DNA hybrid ribonuclease activity
AMD17_RS06035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMD17_RS06040	COG0631	protein serine/threonine phosphatase activity
AMD17_RS06055	COG0859	PFAM glycosyl transferase family 9
AMD17_RS06060	COG3642	lipopolysaccharide core region biosynthetic process
AMD17_RS06065	COG1234	tRNA 3'-trailer cleavage
AMD17_RS06070	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AMD17_RS06080	COG0315	cyclic pyranopterin monophosphate synthase activity
AMD17_RS06085	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AMD17_RS06090	COG0314	molybdopterin synthase activity
AMD17_RS06145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AMD17_RS06150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AMD17_RS06155	COG0537	adenosine 5'-monophosphoramidase activity
AMD17_RS06175	COG0714	Associated with various cellular activities
AMD17_RS06195	COG0424	maF-like protein
AMD17_RS06200	COG1399	metal-binding, possibly nucleic acid-binding protein
AMD17_RS06205	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AMD17_RS06210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMD17_RS06225	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS06240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMD17_RS06245	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AMD17_RS06270	COG3829	transcription factor binding
AMD17_RS06290	COG3609	addiction module antidote protein, CC2985 family
AMD17_RS06310	COG2373	Large extracellular alpha-helical protein
AMD17_RS06325	COG4953	penicillin-binding protein 1C
AMD17_RS06335	COG0678	peroxiredoxin activity
AMD17_RS06355	COG0330	HflC and HflK could
AMD17_RS06360	COG0330	HflC and HflK could
AMD17_RS06370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AMD17_RS06375	COG0308	aminopeptidase N
AMD17_RS06385	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS06390	COG1309	transcriptional regulator
AMD17_RS06465	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AMD17_RS06475	COG3387	PFAM Glycoside hydrolase 15-related
AMD17_RS06480	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS06485	COG3537	Alpha-1,2-mannosidase
AMD17_RS06505	COG0492	ferredoxin-NADP+ reductase activity
AMD17_RS06530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMD17_RS06535	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AMD17_RS06540	COG2080	2 iron, 2 sulfur cluster binding
AMD17_RS06575	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMD17_RS06590	COG0587	DNA-directed DNA polymerase activity
AMD17_RS06605	COG1297	OPT oligopeptide transporter protein
AMD17_RS06620	COG0823	Involved in the tonB-independent uptake of proteins
AMD17_RS06620	COG1506	peptidase
AMD17_RS06635	COG2207	Transcriptional regulator
AMD17_RS06635	COG1917	Cupin 2, conserved barrel domain protein
AMD17_RS06650	COG0753	catalase activity
AMD17_RS06655	COG0656	L-ascorbic acid biosynthetic process
AMD17_RS06665	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMD17_RS06665	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMD17_RS06670	COG2814	Major facilitator Superfamily
AMD17_RS06685	COG2194	sulfuric ester hydrolase activity
AMD17_RS06700	COG0745	RESPONSE REGULATOR receiver
AMD17_RS06705	COG0642	Histidine kinase
AMD17_RS06715	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AMD17_RS06720	COG2894	cell division
AMD17_RS06725	COG0850	regulation of cytokinetic process
AMD17_RS06740	COG4585	Histidine kinase
AMD17_RS06745	COG2197	response regulator
AMD17_RS06760	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AMD17_RS06785	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AMD17_RS06795	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AMD17_RS06815	COG1946	Acyl-CoA thioesterase
AMD17_RS06830	COG0824	Thioesterase
AMD17_RS06835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AMD17_RS06840	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AMD17_RS06845	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AMD17_RS06850	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AMD17_RS06855	COG0268	Binds directly to 16S ribosomal RNA
AMD17_RS06865	COG0196	riboflavin kinase activity
AMD17_RS06870	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AMD17_RS06875	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AMD17_RS06880	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AMD17_RS06895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMD17_RS06900	COG1845	cytochrome c oxidase, subunit III
AMD17_RS06905	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AMD17_RS06920	COG3152	Membrane
AMD17_RS06930	COG2207	Transcriptional regulator
AMD17_RS06935	COG0326	Molecular chaperone. Has ATPase activity
AMD17_RS06945	COG1366	Belongs to the anti-sigma-factor antagonist family
AMD17_RS06950	COG1366	Belongs to the anti-sigma-factor antagonist family
AMD17_RS06955	COG2172	sigma factor antagonist activity
AMD17_RS06980	COG4771	TonB-dependent receptor
AMD17_RS06990	COG5507	3-demethylubiquinone-9 3-methyltransferase
AMD17_RS06995	COG2205	protein histidine kinase activity
AMD17_RS07005	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AMD17_RS07010	COG4999	Histidine kinase
AMD17_RS07010	COG3850	Histidine kinase
AMD17_RS07010	COG3437	response regulator, receiver
AMD17_RS07010	COG2205	protein histidine kinase activity
AMD17_RS07015	COG0784	Response regulator, receiver
AMD17_RS07015	COG4191	Histidine kinase
AMD17_RS07045	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMD17_RS07050	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AMD17_RS07060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMD17_RS07065	COG0228	four-way junction DNA binding
AMD17_RS07070	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AMD17_RS07075	COG0336	Belongs to the RNA methyltransferase TrmD family
AMD17_RS07080	COG0335	large ribosomal subunit rRNA binding
AMD17_RS07110	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AMD17_RS07120	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AMD17_RS07130	COG3209	COG3209 Rhs family protein
AMD17_RS07150	COG3250	beta-galactosidase activity
AMD17_RS07155	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AMD17_RS07175	COG1960	acyl-CoA dehydrogenase activity
AMD17_RS07180	COG1024	Enoyl-CoA hydratase
AMD17_RS07200	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMD17_RS07200	COG1024	Enoyl-CoA hydratase
AMD17_RS07215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMD17_RS07220	COG0481	GTPase activity
AMD17_RS07235	COG0571	ribonuclease III activity
AMD17_RS07240	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AMD17_RS07245	COG1381	Involved in DNA repair and RecF pathway recombination
AMD17_RS07255	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMD17_RS07260	COG2954	triphosphatase activity
AMD17_RS07265	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AMD17_RS07270	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AMD17_RS07275	COG3046	protein related to deoxyribodipyrimidine photolyase
AMD17_RS07280	COG1472	Belongs to the glycosyl hydrolase 3 family
AMD17_RS07285	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AMD17_RS07290	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AMD17_RS07295	COG1278	Cold shock
AMD17_RS07300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMD17_RS07310	COG1201	RNA secondary structure unwinding
AMD17_RS07315	COG1793	dna ligase
AMD17_RS07325	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AMD17_RS07325	COG1793	dna ligase
AMD17_RS07355	COG0183	Belongs to the thiolase family
AMD17_RS07375	COG1451	nucleotide metabolic process
AMD17_RS07380	COG5487	UPF0391 membrane protein
AMD17_RS07390	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AMD17_RS07410	COG1077	Cell shape determining protein MreB Mrl
AMD17_RS07415	COG1047	Peptidyl-prolyl cis-trans
AMD17_RS07425	COG2824	Alkylphosphonate utilization operon protein PhnA
AMD17_RS07430	COG1902	pentaerythritol trinitrate reductase activity
AMD17_RS07435	COG2814	Major facilitator Superfamily
AMD17_RS07470	COG0392	lysyltransferase activity
AMD17_RS07470	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AMD17_RS07480	COG0251	oxidation-reduction process
AMD17_RS07485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMD17_RS07500	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMD17_RS07525	COG1595	DNA-templated transcription, initiation
AMD17_RS07545	COG2878	Part of a membrane complex involved in electron transport
AMD17_RS07555	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMD17_RS07555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMD17_RS07570	COG1131	(ABC) transporter
AMD17_RS07575	COG0346	lactoylglutathione lyase activity
AMD17_RS07580	COG0833	amino acid
AMD17_RS07585	COG2040	homocysteine
AMD17_RS07595	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AMD17_RS07615	COG1695	Transcriptional regulator
AMD17_RS07635	COG1981	membrane
AMD17_RS07650	COG0825	malonyl-CoA metabolic process
AMD17_RS07660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AMD17_RS07665	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMD17_RS07670	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMD17_RS07675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMD17_RS07680	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMD17_RS07695	COG0750	zinc metalloprotease
AMD17_RS07700	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AMD17_RS07705	COG0575	Belongs to the CDS family
AMD17_RS07710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AMD17_RS07715	COG0233	cytoplasmic translational termination
AMD17_RS07720	COG0528	UMP kinase activity
AMD17_RS07730	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AMD17_RS07735	COG0052	Belongs to the universal ribosomal protein uS2 family
AMD17_RS07775	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AMD17_RS07785	COG1393	Belongs to the ArsC family
AMD17_RS07790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMD17_RS07795	COG0367	asparagine synthase
AMD17_RS07805	COG4774	siderophore transport
AMD17_RS07825	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMD17_RS07855	COG1566	PFAM secretion protein HlyD family protein
AMD17_RS07860	COG2814	Major facilitator Superfamily
AMD17_RS07910	COG0339	signal peptide processing
AMD17_RS07915	COG0386	Belongs to the glutathione peroxidase family
AMD17_RS07970	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AMD17_RS07975	COG0084	hydrolase, TatD family'
AMD17_RS07990	COG1960	acyl-CoA dehydrogenase activity
AMD17_RS08010	COG0367	asparagine synthase
AMD17_RS08020	COG0305	Participates in initiation and elongation during chromosome replication
AMD17_RS08025	COG0415	Belongs to the DNA photolyase family
AMD17_RS08035	COG0583	DNA-binding transcription factor activity
AMD17_RS08080	COG3706	GGDEF domain
AMD17_RS08185	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AMD17_RS08200	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMD17_RS08210	COG0497	DNA recombination
AMD17_RS08215	COG1420	regulation of RNA biosynthetic process
AMD17_RS08220	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMD17_RS08225	COG0443	Heat shock 70 kDa protein
AMD17_RS08230	COG0484	heat shock protein binding
AMD17_RS08235	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AMD17_RS08265	COG0583	DNA-binding transcription factor activity
AMD17_RS08270	COG1132	(ABC) transporter
AMD17_RS08305	COG2850	peptidyl-arginine hydroxylation
AMD17_RS08325	COG1253	flavin adenine dinucleotide binding
AMD17_RS08355	COG1131	(ABC) transporter
AMD17_RS08360	COG1725	Transcriptional regulator
AMD17_RS08365	COG0386	Belongs to the glutathione peroxidase family
AMD17_RS08380	COG2900	Belongs to the SlyX family
AMD17_RS08405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMD17_RS08415	COG1410	methionine synthase
AMD17_RS08415	COG0646	methionine synthase
AMD17_RS08420	COG1410	methionine synthase
AMD17_RS08420	COG0646	methionine synthase
AMD17_RS08425	COG2226	methyltransferase
AMD17_RS08430	COG1960	acyl-CoA dehydrogenase activity
AMD17_RS08445	COG0557	exoribonuclease II activity
AMD17_RS08455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMD17_RS08465	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMD17_RS08475	COG0704	Plays a role in the regulation of phosphate uptake
AMD17_RS08480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMD17_RS08485	COG0581	inorganic phosphate transmembrane transporter activity
AMD17_RS08490	COG0573	inorganic phosphate transmembrane transporter activity
AMD17_RS08495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AMD17_RS08520	COG0659	secondary active sulfate transmembrane transporter activity
AMD17_RS08525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AMD17_RS08535	COG1024	Enoyl-CoA hydratase
AMD17_RS08545	COG0494	nUDIX hydrolase
AMD17_RS08580	COG0488	(ABC) transporter
AMD17_RS08585	COG0116	Belongs to the methyltransferase superfamily
AMD17_RS08585	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AMD17_RS08590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AMD17_RS08615	COG2925	Exonuclease
AMD17_RS08620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMD17_RS08625	COG3844	kynureninase activity
AMD17_RS08635	COG0662	Cupin 2, conserved barrel domain protein
AMD17_RS08640	COG0288	reversible hydration of carbon dioxide
AMD17_RS08700	COG2808	Putative FMN-binding domain
AMD17_RS08720	COG0017	Asparaginyl-tRNA synthetase
AMD17_RS08725	COG0316	Belongs to the HesB IscA family
AMD17_RS08730	COG0360	Binds together with S18 to 16S ribosomal RNA
AMD17_RS08735	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AMD17_RS08740	COG0359	binds to the 23S rRNA
AMD17_RS08750	COG3115	cell septum assembly
AMD17_RS08760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMD17_RS08765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMD17_RS08770	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AMD17_RS08780	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AMD17_RS08800	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AMD17_RS08810	COG2986	histidine ammonia-lyase
AMD17_RS08815	COG1228	amidohydrolase
AMD17_RS08860	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AMD17_RS08865	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AMD17_RS08870	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AMD17_RS08875	COG0077	Prephenate dehydratase
AMD17_RS08875	COG1605	Chorismate mutase
AMD17_RS08880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AMD17_RS08895	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AMD17_RS08900	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AMD17_RS08905	COG0583	DNA-binding transcription factor activity
AMD17_RS08935	COG2801	Transposase and inactivated derivatives
AMD17_RS08955	COG0840	transmembrane signaling receptor activity
AMD17_RS08990	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AMD17_RS08995	COG0784	Response regulator, receiver
AMD17_RS08995	COG4191	Histidine kinase
AMD17_RS09010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMD17_RS09020	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AMD17_RS09030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMD17_RS09045	COG1595	DNA-templated transcription, initiation
AMD17_RS09100	COG2244	polysaccharide biosynthetic process
AMD17_RS09130	COG2264	protein methyltransferase activity
AMD17_RS09140	COG0438	transferase activity, transferring glycosyl groups
AMD17_RS09155	COG1136	(ABC) transporter
AMD17_RS09165	COG0477	Major facilitator Superfamily
AMD17_RS09170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMD17_RS09185	COG1253	flavin adenine dinucleotide binding
AMD17_RS09195	COG0306	phosphate transporter
AMD17_RS09220	COG0504	CTP synthase activity
AMD17_RS09225	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AMD17_RS09235	COG0148	phosphopyruvate hydratase activity
AMD17_RS09240	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AMD17_RS09245	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AMD17_RS09250	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AMD17_RS09255	COG0585	pseudouridine synthase activity
AMD17_RS09260	COG2840	Smr protein MutS2
AMD17_RS09265	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AMD17_RS09270	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AMD17_RS09275	COG1238	metal cluster binding
AMD17_RS09290	COG1534	Rna-binding protein
AMD17_RS09295	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AMD17_RS09305	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMD17_RS09310	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMD17_RS09320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AMD17_RS09325	COG1546	Belongs to the CinA family
AMD17_RS09335	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMD17_RS09340	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AMD17_RS09345	COG2137	regulation of response to DNA damage stimulus
AMD17_RS09350	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMD17_RS09355	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AMD17_RS09370	COG1741	Belongs to the pirin family
AMD17_RS09380	COG0583	DNA-binding transcription factor activity
AMD17_RS09405	COG0352	thiamine-phosphate diphosphorylase activity
AMD17_RS09405	COG0351	phosphomethylpyrimidine kinase
AMD17_RS09420	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AMD17_RS09425	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AMD17_RS09440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMD17_RS09450	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AMD17_RS09455	COG3734	2-keto-3-deoxy-galactonokinase
AMD17_RS09465	COG4948	Mandelate Racemase Muconate Lactonizing
AMD17_RS09470	COG0800	Aldolase
AMD17_RS09510	COG1501	Belongs to the glycosyl hydrolase 31 family
AMD17_RS09520	COG1070	Carbohydrate kinase
AMD17_RS09525	COG2115	Belongs to the xylose isomerase family
AMD17_RS09530	COG0477	Major facilitator Superfamily
AMD17_RS09540	COG0860	N-Acetylmuramoyl-L-alanine amidase
AMD17_RS09545	COG1469	GTP cyclohydrolase I activity
AMD17_RS09565	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AMD17_RS09570	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AMD17_RS09575	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AMD17_RS09580	COG0166	Belongs to the GPI family
AMD17_RS09600	COG1472	Belongs to the glycosyl hydrolase 3 family
AMD17_RS09610	COG5001	Diguanylate cyclase
AMD17_RS09610	COG3706	GGDEF domain
AMD17_RS09610	COG4251	negative regulation of phosphorylation
AMD17_RS09610	COG2203	Gaf domain
AMD17_RS09615	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AMD17_RS09620	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AMD17_RS09630	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AMD17_RS09635	COG0671	phosphoesterase, PA-phosphatase related
AMD17_RS09645	COG1794	racemase activity, acting on amino acids and derivatives
AMD17_RS09650	COG0697	spore germination
AMD17_RS09655	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AMD17_RS09660	COG0167	dihydroorotate dehydrogenase activity
AMD17_RS09675	COG1012	belongs to the aldehyde dehydrogenase family
AMD17_RS09690	COG1215	transferase activity, transferring glycosyl groups
AMD17_RS09695	COG1649	PFAM Uncharacterised BCR, COG1649
AMD17_RS09695	COG0726	polysaccharide deacetylase
AMD17_RS09710	COG3210	domain, Protein
AMD17_RS09715	COG3210	domain, Protein
AMD17_RS09755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMD17_RS09760	COG0124	histidyl-tRNA synthetase
AMD17_RS09770	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AMD17_RS09775	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AMD17_RS09780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMD17_RS09785	COG0131	Imidazoleglycerol-phosphate dehydratase
AMD17_RS09785	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AMD17_RS09790	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AMD17_RS09795	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AMD17_RS09800	COG0107	imidazoleglycerol-phosphate synthase activity
AMD17_RS09805	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AMD17_RS09805	COG0140	phosphoribosyl-ATP diphosphatase activity
AMD17_RS09820	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AMD17_RS09825	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AMD17_RS09830	COG0235	Class ii aldolase
AMD17_RS09835	COG0531	amino acid
AMD17_RS09840	COG0531	amino acid
AMD17_RS09850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMD17_RS09855	COG0277	FAD linked oxidase domain protein
AMD17_RS09875	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMD17_RS09920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMD17_RS09925	COG2258	MOSC domain
AMD17_RS09930	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMD17_RS09935	COG0505	Belongs to the CarA family
AMD17_RS09945	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AMD17_RS09950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMD17_RS09960	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AMD17_RS10005	COG3279	Response regulator of the LytR AlgR family
AMD17_RS10010	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AMD17_RS10015	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AMD17_RS10025	COG2198	Histidine kinase
AMD17_RS10025	COG2205	protein histidine kinase activity
AMD17_RS10025	COG0784	Response regulator, receiver
AMD17_RS10030	COG1024	Enoyl-CoA hydratase
AMD17_RS10035	COG0318	PFAM AMP-dependent synthetase and ligase
AMD17_RS10065	COG2267	carboxylic ester hydrolase activity
AMD17_RS10075	COG2201	protein-glutamate methylesterase activity
AMD17_RS10080	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AMD17_RS10090	COG0840	transmembrane signaling receptor activity
AMD17_RS10095	COG0840	transmembrane signaling receptor activity
AMD17_RS10100	COG0840	transmembrane signaling receptor activity
AMD17_RS10110	COG0840	transmembrane signaling receptor activity
AMD17_RS10115	COG0840	transmembrane signaling receptor activity
AMD17_RS10120	COG0840	transmembrane signaling receptor activity
AMD17_RS10125	COG0840	transmembrane signaling receptor activity
AMD17_RS10140	COG0840	transmembrane signaling receptor activity
AMD17_RS10155	COG0840	transmembrane signaling receptor activity
AMD17_RS10160	COG2198	Histidine kinase
AMD17_RS10160	COG0643	Histidine kinase
AMD17_RS10165	COG0745	RESPONSE REGULATOR receiver
AMD17_RS10175	COG0835	chemotaxis
AMD17_RS10185	COG1360	Flagellar Motor Protein
AMD17_RS10190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMD17_RS10275	COG0641	radical SAM
AMD17_RS10290	COG2198	Histidine kinase
AMD17_RS10290	COG0784	Response regulator, receiver
AMD17_RS10290	COG0643	Histidine kinase
AMD17_RS10320	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMD17_RS10350	COG1684	flagellar biosynthetic protein fliR
AMD17_RS10365	COG3190	flagellar
AMD17_RS10415	COG1677	Flagellar hook-basal body complex protein FliE
AMD17_RS10445	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS10450	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS10455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMD17_RS10475	COG2201	protein-glutamate methylesterase activity
AMD17_RS10505	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AMD17_RS10510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMD17_RS10515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMD17_RS10525	COG1705	Flagellar rod assembly protein muramidase FlgJ
AMD17_RS10525	COG3951	Flagellar rod assembly protein muramidase FlgJ
AMD17_RS10530	COG1706	bacterial-type flagellum-dependent cell motility
AMD17_RS10535	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AMD17_RS10545	COG4787	bacterial-type flagellum-dependent cell motility
AMD17_RS10555	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AMD17_RS10560	COG1558	bacterial-type flagellum-dependent cell motility
AMD17_RS10570	COG0784	Response regulator, receiver
AMD17_RS10570	COG0835	chemotaxis
AMD17_RS10590	COG5002	protein histidine kinase activity
AMD17_RS10620	COG2915	High frequency lysogenization protein hflD homolog
AMD17_RS10625	COG0482	sulfurtransferase activity
AMD17_RS10640	COG0542	response to heat
AMD17_RS10650	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AMD17_RS10660	COG0492	ferredoxin-NADP+ reductase activity
AMD17_RS10665	COG1674	ftsk spoiiie
AMD17_RS10675	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AMD17_RS10685	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AMD17_RS10690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AMD17_RS10700	COG0183	Belongs to the thiolase family
AMD17_RS10705	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMD17_RS10705	COG1024	Enoyl-CoA hydratase
AMD17_RS10720	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMD17_RS10730	COG1426	Protein conserved in bacteria
AMD17_RS10740	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMD17_RS10745	COG1160	GTP binding
AMD17_RS10750	COG0303	'Molybdopterin
AMD17_RS10755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMD17_RS10790	COG0708	Exodeoxyribonuclease III
AMD17_RS10800	COG0303	'Molybdopterin
AMD17_RS10805	COG0746	molybdenum cofactor guanylyltransferase activity
AMD17_RS10820	COG1914	H( )-stimulated, divalent metal cation uptake system
AMD17_RS10835	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AMD17_RS10840	COG0668	transmembrane transport
AMD17_RS10850	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AMD17_RS10865	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS10870	COG1183	phosphatidylcholine synthase activity
AMD17_RS10880	COG3243	poly(R)-hydroxyalkanoic acid synthase
AMD17_RS10895	COG0723	plastoquinol--plastocyanin reductase activity
AMD17_RS10895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMD17_RS10905	COG2183	response to ionizing radiation
AMD17_RS10910	COG2205	protein histidine kinase activity
AMD17_RS10910	COG0784	Response regulator, receiver
AMD17_RS10975	COG0800	Aldolase
AMD17_RS10980	COG0129	dihydroxy-acid dehydratase activity
AMD17_RS10985	COG0363	glucosamine-6-phosphate deaminase activity
AMD17_RS10990	COG0837	glucose binding
AMD17_RS10995	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AMD17_RS11015	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AMD17_RS11030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AMD17_RS11035	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AMD17_RS11045	COG4591	ABC-type transport system involved in lipoprotein release permease component
AMD17_RS11050	COG1136	(ABC) transporter
AMD17_RS11065	COG0811	peptide transport
AMD17_RS11075	COG1132	(ABC) transporter
AMD17_RS11080	COG1663	tetraacyldisaccharide 4'-kinase activity
AMD17_RS11085	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AMD17_RS11090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AMD17_RS11100	COG0322	excinuclease ABC activity
AMD17_RS11105	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMD17_RS11125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMD17_RS11130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMD17_RS11145	COG2801	Transposase and inactivated derivatives
AMD17_RS11155	COG0582	viral genome integration into host DNA
AMD17_RS11165	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AMD17_RS11185	COG1054	Belongs to the UPF0176 family
AMD17_RS11195	COG1530	ribonuclease E activity
AMD17_RS11205	COG3064	Membrane
AMD17_RS11210	COG0428	transporter
AMD17_RS11220	COG2154	pterin-4-alpha-carbinolamine dehydratase
AMD17_RS11225	COG0316	Belongs to the HesB IscA family
AMD17_RS11225	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AMD17_RS11280	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS11315	COG1238	metal cluster binding
AMD17_RS11350	COG3279	Response regulator of the LytR AlgR family
AMD17_RS11395	COG4566	intracellular signal transduction
AMD17_RS11405	COG5001	Diguanylate cyclase
AMD17_RS11420	COG3685	Protein conserved in bacteria
AMD17_RS11435	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMD17_RS11435	COG1648	precorrin-2 dehydrogenase activity
AMD17_RS11450	COG2814	Major facilitator Superfamily
AMD17_RS11470	COG1335	isochorismatase
AMD17_RS11485	COG2197	response regulator
AMD17_RS11505	COG0583	DNA-binding transcription factor activity
AMD17_RS11510	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AMD17_RS11515	COG3002	Belongs to the UPF0753 family
AMD17_RS11530	COG1396	sequence-specific DNA binding
AMD17_RS11535	COG5489	Protein of unknown function (DUF736)
AMD17_RS11540	COG2003	Belongs to the UPF0758 family
AMD17_RS11565	COG0582	viral genome integration into host DNA
AMD17_RS11580	COG4774	siderophore transport
AMD17_RS11595	COG2336	PFAM SpoVT AbrB
AMD17_RS11620	COG4206	TonB-dependent receptor
AMD17_RS11640	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AMD17_RS11640	COG2273	Hydrolase Family 16
AMD17_RS11660	COG2274	protein secretion by the type I secretion system
AMD17_RS11710	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AMD17_RS11715	COG0270	DNA (cytosine-5-)-methyltransferase activity
AMD17_RS11765	COG4804	nuclease activity
AMD17_RS11785	COG5006	permease, DMT superfamily
AMD17_RS11800	COG2249	NAD(P)H dehydrogenase (quinone) activity
AMD17_RS11810	COG3938	Belongs to the proline racemase family
AMD17_RS11825	COG2807	transmembrane transport
AMD17_RS11830	COG2207	Transcriptional regulator
AMD17_RS11980	COG0210	DNA helicase
AMD17_RS12060	COG2084	Dehydrogenase
AMD17_RS12080	COG2003	Belongs to the UPF0758 family
AMD17_RS12115	COG0582	viral genome integration into host DNA
AMD17_RS12120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMD17_RS12120	COG0519	Catalyzes the synthesis of GMP from XMP
AMD17_RS12130	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AMD17_RS12140	COG0475	glutathione-regulated potassium exporter activity
AMD17_RS12140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AMD17_RS12145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AMD17_RS12155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMD17_RS12160	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AMD17_RS12170	COG0776	regulation of translation
AMD17_RS12175	COG0539	negative regulation of cytoplasmic translation
AMD17_RS12180	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AMD17_RS12195	COG2957	Belongs to the agmatine deiminase family
AMD17_RS12200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMD17_RS12225	COG0395	ABC-type sugar transport system, permease component
AMD17_RS12230	COG1175	transmembrane transport
AMD17_RS12260	COG2350	Protein conserved in bacteria
AMD17_RS12265	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AMD17_RS12270	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AMD17_RS12275	COG1187	pseudouridine synthase activity
AMD17_RS12295	COG0436	Aminotransferase
AMD17_RS12300	COG4133	protoheme IX ABC transporter activity
AMD17_RS12320	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AMD17_RS12325	COG1138	Cytochrome C-type biogenesis protein
AMD17_RS12345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMD17_RS12350	COG1278	Cold shock
AMD17_RS12355	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AMD17_RS12360	COG4988	ABC transporter
AMD17_RS12370	COG1294	oxidase, subunit
AMD17_RS12395	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AMD17_RS12400	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AMD17_RS12410	COG0165	Argininosuccinate lyase
AMD17_RS12415	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AMD17_RS12425	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMD17_RS12430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMD17_RS12440	COG0137	argininosuccinate synthase activity
AMD17_RS12445	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AMD17_RS12455	COG0215	cysteine-tRNA ligase activity
AMD17_RS12460	COG2166	iron-sulfur cluster assembly
AMD17_RS12480	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AMD17_RS12485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMD17_RS12510	COG4302	ethanolamine ammonia-lyase activity
AMD17_RS12540	COG2963	transposase activity
AMD17_RS12560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMD17_RS12565	COG0402	S-adenosylhomocysteine deaminase activity
AMD17_RS12575	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMD17_RS12580	COG1509	lysine 2,3-aminomutase activity
AMD17_RS12585	COG5001	Diguanylate cyclase
AMD17_RS12585	COG3300	MHYT domain
AMD17_RS12600	COG0483	inositol monophosphate 1-phosphatase activity
AMD17_RS12605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AMD17_RS12620	COG0488	(ABC) transporter
AMD17_RS12625	COG0513	Belongs to the DEAD box helicase family
AMD17_RS12630	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AMD17_RS12635	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AMD17_RS12645	COG0625	glutathione transferase activity
AMD17_RS12655	COG4681	YaeQ
AMD17_RS12660	COG2081	HI0933 family
AMD17_RS12670	COG0501	Belongs to the peptidase M48B family
AMD17_RS12675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMD17_RS12680	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS12700	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AMD17_RS12705	COG0860	N-Acetylmuramoyl-L-alanine amidase
AMD17_RS12710	COG0802	atpase or kinase
AMD17_RS12715	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AMD17_RS12715	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AMD17_RS12720	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AMD17_RS12725	COG1570	exodeoxyribonuclease VII activity
AMD17_RS12735	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMD17_RS12915	COG0835	chemotaxis
AMD17_RS12920	COG0840	transmembrane signaling receptor activity
AMD17_RS12925	COG2094	Belongs to the DNA glycosylase MPG family
AMD17_RS12930	COG1201	RNA secondary structure unwinding
AMD17_RS12945	COG2969	positive regulation of protein catabolic process
AMD17_RS12950	COG0625	glutathione transferase activity
AMD17_RS12955	COG2857	Cytochrome c1
AMD17_RS12960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AMD17_RS12965	COG0723	plastoquinol--plastocyanin reductase activity
AMD17_RS12970	COG0741	lytic transglycosylase activity
AMD17_RS12985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMD17_RS12990	COG1702	phosphate starvation-inducible protein PhoH
AMD17_RS13000	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AMD17_RS13010	COG4535	Mg2 and Co2 transporter CorC
AMD17_RS13025	COG1012	belongs to the aldehyde dehydrogenase family
AMD17_RS13035	COG1177	transmembrane transport
AMD17_RS13040	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMD17_RS13045	COG3842	ATPase activity
AMD17_RS13065	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AMD17_RS13080	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AMD17_RS13085	COG0174	glutamine synthetase
AMD17_RS13090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMD17_RS13100	COG2703	oxygen carrier activity
AMD17_RS13105	COG0477	Major facilitator Superfamily
AMD17_RS13115	COG0243	molybdopterin cofactor binding
AMD17_RS13120	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AMD17_RS13125	COG2223	nitrite transmembrane transporter activity
AMD17_RS13130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMD17_RS13140	COG2733	membrane
AMD17_RS13145	COG0784	Response regulator, receiver
AMD17_RS13145	COG5002	protein histidine kinase activity
AMD17_RS13145	COG2205	protein histidine kinase activity
AMD17_RS13155	COG0477	Major facilitator Superfamily
AMD17_RS13160	COG2902	Dehydrogenase
AMD17_RS13170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMD17_RS13175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMD17_RS13180	COG1609	Transcriptional regulator
AMD17_RS13185	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMD17_RS13185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMD17_RS13190	COG1105	Belongs to the carbohydrate kinase PfkB family
AMD17_RS13195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMD17_RS13195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMD17_RS13230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMD17_RS13240	COG1862	Preprotein translocase
AMD17_RS13245	COG0343	queuine tRNA-ribosyltransferase activity
AMD17_RS13250	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AMD17_RS13290	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AMD17_RS13295	COG3291	Pkd domain containing protein
AMD17_RS13305	COG0405	Gamma-glutamyltransferase
AMD17_RS13310	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMD17_RS13325	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AMD17_RS13330	COG0742	ribosomal rna small subunit methyltransferase
AMD17_RS13335	COG0326	Molecular chaperone. Has ATPase activity
AMD17_RS13405	COG0531	amino acid
AMD17_RS13420	COG0006	proline dipeptidase activity
AMD17_RS13430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMD17_RS13445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMD17_RS13450	COG3938	Belongs to the proline racemase family
AMD17_RS13460	COG0552	protein localization to endoplasmic reticulum
AMD17_RS13465	COG1194	a g-specific adenine glycosylase
AMD17_RS13470	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AMD17_RS13475	COG4191	Histidine kinase
AMD17_RS13475	COG0784	Response regulator, receiver
AMD17_RS13490	COG0322	excinuclease ABC activity
AMD17_RS13505	COG3040	lipid binding
AMD17_RS13515	COG1960	acyl-CoA dehydrogenase activity
AMD17_RS13525	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AMD17_RS13545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMD17_RS13550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMD17_RS13555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMD17_RS13580	COG0438	transferase activity, transferring glycosyl groups
AMD17_RS13590	COG0438	transferase activity, transferring glycosyl groups
AMD17_RS13595	COG0438	transferase activity, transferring glycosyl groups
AMD17_RS13645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMD17_RS13645	COG0072	phenylalanine-tRNA ligase activity
AMD17_RS13650	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AMD17_RS13665	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AMD17_RS13670	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AMD17_RS13695	COG1082	Xylose isomerase domain protein TIM barrel
AMD17_RS13710	COG0366	Alpha amylase catalytic
AMD17_RS13715	COG2963	transposase activity
AMD17_RS13780	COG2948	multi-organism process
AMD17_RS13800	COG3505	Type IV secretory pathway VirD4
AMD17_RS13815	COG0556	nucleotide-excision repair
AMD17_RS13885	COG4695	Portal protein
AMD17_RS13930	COG3179	chitinase
AMD17_RS14025	COG3275	phosphorelay sensor kinase activity
AMD17_RS14030	COG1611	Belongs to the LOG family
AMD17_RS14040	COG2095	MarC family integral membrane protein
AMD17_RS14050	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AMD17_RS14085	COG1185	polyribonucleotide nucleotidyltransferase activity
AMD17_RS14090	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AMD17_RS14095	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AMD17_RS14100	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AMD17_RS14105	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AMD17_RS14110	COG0195	Participates in both transcription termination and antitermination
AMD17_RS14115	COG0779	Required for maturation of 30S ribosomal subunits
AMD17_RS14125	COG1007	ATP synthesis coupled electron transport
AMD17_RS14150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMD17_RS14155	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMD17_RS14165	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AMD17_RS14170	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AMD17_RS14175	COG0649	NAD binding
AMD17_RS14180	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMD17_RS14185	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMD17_RS14190	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMD17_RS14205	COG0149	triose-phosphate isomerase activity
AMD17_RS14210	COG0300	oxidoreductase activity
AMD17_RS14245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMD17_RS14250	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AMD17_RS14255	COG0159	tryptophan synthase activity
AMD17_RS14265	COG0133	tryptophan synthase activity
AMD17_RS14275	COG0135	phosphoribosylanthranilate isomerase activity
AMD17_RS14280	COG0101	tRNA pseudouridine synthase activity
AMD17_RS14300	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AMD17_RS14305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMD17_RS14310	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AMD17_RS14315	COG2890	protein-(glutamine-N5) methyltransferase activity
AMD17_RS14325	COG0688	phosphatidylethanolamine metabolic process
AMD17_RS14335	COG0433	COG0433 Predicted ATPase
AMD17_RS14340	COG0494	nUDIX hydrolase
AMD17_RS14355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMD17_RS14360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMD17_RS14385	COG0717	Belongs to the dCTP deaminase family
AMD17_RS14390	COG0489	protein tyrosine kinase activity
AMD17_RS14410	COG3590	peptidase
AMD17_RS14415	COG3590	peptidase
AMD17_RS14435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMD17_RS14440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMD17_RS14445	COG2311	Membrane
AMD17_RS14450	COG1047	Peptidyl-prolyl cis-trans
AMD17_RS14455	COG0791	NLP P60 protein
AMD17_RS14460	COG0791	NLP P60 protein
AMD17_RS14470	COG4106	trans-aconitate 2-methyltransferase activity
AMD17_RS14475	COG1301	dicarboxylic acid transport
AMD17_RS14480	COG1785	Belongs to the alkaline phosphatase family
AMD17_RS14485	COG0037	tRNA processing
AMD17_RS14490	COG1722	exodeoxyribonuclease VII activity
AMD17_RS14495	COG0142	geranyltranstransferase activity
AMD17_RS14500	COG4104	PAAR repeat-containing protein
AMD17_RS14510	COG0312	modulator of DNA gyrase
AMD17_RS14515	COG3028	Belongs to the UPF0307 family
AMD17_RS14520	COG0312	modulator of DNA gyrase
AMD17_RS14530	COG3164	Protein of unknown function
AMD17_RS14540	COG0424	maF-like protein
AMD17_RS14545	COG2968	Membrane
AMD17_RS14560	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AMD17_RS14575	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AMD17_RS14590	COG0495	leucyl-tRNA aminoacylation
AMD17_RS14600	COG3118	belongs to the thioredoxin family
AMD17_RS14625	COG2155	Conserved Protein
AMD17_RS14670	COG1132	(ABC) transporter
AMD17_RS14695	COG1538	Outer membrane efflux protein
AMD17_RS14700	COG0745	RESPONSE REGULATOR receiver
AMD17_RS14705	COG5000	phosphorelay sensor kinase activity
AMD17_RS14705	COG5002	protein histidine kinase activity
AMD17_RS14710	COG0475	glutathione-regulated potassium exporter activity
AMD17_RS14720	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AMD17_RS14745	COG1187	pseudouridine synthase activity
AMD17_RS14750	COG5002	protein histidine kinase activity
AMD17_RS14750	COG5001	Diguanylate cyclase
AMD17_RS14865	COG0667	Aldo Keto reductase
AMD17_RS14870	COG2814	Major facilitator Superfamily
AMD17_RS14875	COG0583	DNA-binding transcription factor activity
AMD17_RS14885	COG2207	Transcriptional regulator
AMD17_RS14895	COG1309	transcriptional regulator
AMD17_RS14920	COG0735	belongs to the Fur family
AMD17_RS14925	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMD17_RS14950	COG4452	Inner membrane protein CreD
AMD17_RS14960	COG2205	protein histidine kinase activity
AMD17_RS14965	COG0745	RESPONSE REGULATOR receiver
AMD17_RS14970	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AMD17_RS14980	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AMD17_RS15015	COG2198	Histidine kinase
AMD17_RS15015	COG0643	Histidine kinase
AMD17_RS15020	COG0840	transmembrane signaling receptor activity
AMD17_RS15025	COG0835	chemotaxis
AMD17_RS15030	COG2199	diguanylate cyclase activity
AMD17_RS15030	COG2200	EAL domain
AMD17_RS15030	COG2202	Pas domain
AMD17_RS15035	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AMD17_RS15040	COG2201	protein-glutamate methylesterase activity
AMD17_RS15045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMD17_RS15050	COG3590	peptidase
AMD17_RS15060	COG0588	phosphoglycerate mutase activity
AMD17_RS15065	COG1515	deoxyribonuclease V activity
AMD17_RS15075	COG1741	Belongs to the pirin family
AMD17_RS15090	COG1741	Belongs to the pirin family
AMD17_RS15095	COG1966	Carbon starvation protein
AMD17_RS15100	COG2879	small protein
AMD17_RS15155	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMD17_RS15160	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AMD17_RS15165	COG2080	2 iron, 2 sulfur cluster binding
AMD17_RS15175	COG2203	Gaf domain
AMD17_RS15175	COG3706	GGDEF domain
AMD17_RS15175	COG4251	negative regulation of phosphorylation
AMD17_RS15175	COG5001	Diguanylate cyclase
AMD17_RS15215	COG0629	single-stranded DNA binding
AMD17_RS15220	COG0142	geranyltranstransferase activity
AMD17_RS15230	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AMD17_RS15245	COG0527	aspartate kinase activity
AMD17_RS15250	COG0384	phenazine biosynthesis protein PhzF
AMD17_RS15255	COG0384	phenazine biosynthesis protein PhzF
AMD17_RS15265	COG1764	response to oxidative stress
AMD17_RS15270	COG0540	Belongs to the ATCase OTCase family
AMD17_RS15275	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AMD17_RS15280	COG1678	Uncharacterized ACR, COG1678
AMD17_RS15290	COG0519	Catalyzes the synthesis of GMP from XMP
AMD17_RS15300	COG5297	Belongs to the glycosyl hydrolase family 6
AMD17_RS15315	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AMD17_RS15330	COG0739	heme binding
AMD17_RS15350	COG0693	protein deglycase activity
AMD17_RS15360	COG1959	2 iron, 2 sulfur cluster binding
AMD17_RS15365	COG0719	Fe-S assembly protein
AMD17_RS15370	COG0396	ATPase activity
AMD17_RS15375	COG0719	Fe-S assembly protein
AMD17_RS15380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMD17_RS15390	COG2146	nitrite reductase [NAD(P)H] activity
AMD17_RS15395	COG4774	siderophore transport
AMD17_RS15400	COG3128	pkhd-type hydroxylase
AMD17_RS15425	COG1477	protein flavinylation
AMD17_RS15430	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AMD17_RS15445	COG1555	photosystem II stabilization
AMD17_RS15450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMD17_RS15460	COG3178	'Phosphotransferase
AMD17_RS15465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AMD17_RS15475	COG0628	permease
AMD17_RS15485	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AMD17_RS15495	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AMD17_RS15515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AMD17_RS15520	COG0271	Belongs to the BolA IbaG family
AMD17_RS15530	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AMD17_RS15540	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AMD17_RS15545	COG1137	ATPase activity
AMD17_RS15560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMD17_RS15565	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AMD17_RS15570	COG1660	Displays ATPase and GTPase activities
AMD17_RS15580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMD17_RS15585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMD17_RS15590	COG2239	Acts as a magnesium transporter
AMD17_RS15600	COG1294	oxidase, subunit
AMD17_RS15605	COG1271	oxidase subunit
AMD17_RS15615	COG1113	amino acid transport
AMD17_RS15635	COG2197	response regulator
AMD17_RS15640	COG0531	amino acid
AMD17_RS15660	COG1234	tRNA 3'-trailer cleavage
AMD17_RS15695	COG2814	Major facilitator Superfamily
AMD17_RS15705	COG0754	glutathionylspermidine amidase activity
AMD17_RS15730	COG1842	Phage shock protein A
AMD17_RS15740	COG0259	pyridoxamine-phosphate oxidase activity
AMD17_RS15745	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AMD17_RS15750	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMD17_RS15760	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AMD17_RS15835	COG2814	Major facilitator Superfamily
AMD17_RS15855	COG2198	Histidine kinase
AMD17_RS15855	COG0784	Response regulator, receiver
AMD17_RS15855	COG2205	protein histidine kinase activity
AMD17_RS15860	COG2353	YceI-like domain
AMD17_RS15880	COG1760	l-serine dehydratase
AMD17_RS15890	COG0460	homoserine dehydrogenase
AMD17_RS15890	COG0527	aspartate kinase activity
AMD17_RS15895	COG0626	cystathionine gamma-synthase activity
AMD17_RS15900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMD17_RS15905	COG0739	heme binding
AMD17_RS15910	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AMD17_RS15915	COG1272	protein, Hemolysin III
AMD17_RS15920	COG2982	Protein involved in outer membrane biogenesis
AMD17_RS15925	COG0517	IMP dehydrogenase activity
AMD17_RS15925	COG0516	GMP reductase activity
AMD17_RS15930	COG0463	Glycosyl transferase, family 2
AMD17_RS15935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMD17_RS15940	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AMD17_RS15950	COG4771	TonB-dependent receptor
AMD17_RS15960	COG1309	transcriptional regulator
AMD17_RS15970	COG1960	acyl-CoA dehydrogenase activity
AMD17_RS15995	COG0509	glycine decarboxylation via glycine cleavage system
AMD17_RS16000	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AMD17_RS16010	COG0330	HflC and HflK could
AMD17_RS16015	COG1742	UPF0060 membrane protein
AMD17_RS16020	COG3956	TIGRFAM MazG family protein
AMD17_RS16030	COG0494	nUDIX hydrolase
AMD17_RS16040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AMD17_RS16045	COG0837	glucose binding
AMD17_RS16060	COG1388	LysM domain
AMD17_RS16060	COG3858	chitin binding
AMD17_RS16065	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AMD17_RS16075	COG1472	Belongs to the glycosyl hydrolase 3 family
AMD17_RS16090	COG0531	amino acid
AMD17_RS16100	COG1486	melibiose metabolic process
AMD17_RS16110	COG3537	Alpha-1,2-mannosidase
AMD17_RS16145	COG3142	Participates in the control of copper homeostasis
AMD17_RS16150	COG1446	asparaginase
AMD17_RS16175	COG0643	Histidine kinase
AMD17_RS16175	COG0784	Response regulator, receiver
AMD17_RS16175	COG2198	Histidine kinase
AMD17_RS16180	COG0840	transmembrane signaling receptor activity
AMD17_RS16185	COG0835	chemotaxis
AMD17_RS16200	COG0189	ligase activity
AMD17_RS16210	COG1397	ADP-ribosylglycohydrolase
AMD17_RS16220	COG1199	ATP-dependent helicase activity
AMD17_RS16230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMD17_RS16235	COG1215	transferase activity, transferring glycosyl groups
AMD17_RS16245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMD17_RS16250	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AMD17_RS16255	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AMD17_RS16260	COG0535	radical SAM domain protein
AMD17_RS16265	COG0535	radical SAM domain protein
AMD17_RS16280	COG0837	glucose binding
AMD17_RS16290	COG1643	Atp-dependent helicase
AMD17_RS16295	COG0783	Belongs to the Dps family
AMD17_RS16300	COG0514	ATP-dependent DNA helicase (RecQ)
AMD17_RS16335	COG0840	transmembrane signaling receptor activity
AMD17_RS16355	COG3920	Histidine kinase
AMD17_RS16360	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AMD17_RS16370	COG0602	queuosine metabolic process
AMD17_RS16380	COG2885	chlorophyll binding
AMD17_RS16385	COG0823	Involved in the tonB-independent uptake of proteins
AMD17_RS16395	COG0848	biopolymer transport protein
AMD17_RS16405	COG0824	Thioesterase
AMD17_RS16410	COG2255	four-way junction helicase activity
AMD17_RS16420	COG3158	transport of potassium into the cell
AMD17_RS16425	COG0632	four-way junction helicase activity
AMD17_RS16430	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AMD17_RS16435	COG0217	transcriptional regulatory protein
AMD17_RS16450	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AMD17_RS16465	COG0477	Major facilitator Superfamily
AMD17_RS16500	COG0488	(ABC) transporter
AMD17_RS16535	COG4651	solute:proton antiporter activity
AMD17_RS16535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AMD17_RS16560	COG4772	TonB-dependent receptor
AMD17_RS16570	COG4264	IucA IucC family
AMD17_RS16585	COG0019	diaminopimelate decarboxylase activity
AMD17_RS16610	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AMD17_RS16620	COG1492	cobalamin metabolic process
AMD17_RS16630	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AMD17_RS16650	COG4206	TonB-dependent receptor
AMD17_RS16655	COG0542	response to heat
AMD17_RS16660	COG1116	anion transmembrane transporter activity
AMD17_RS16665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMD17_RS16670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMD17_RS16675	COG0667	Aldo Keto reductase
AMD17_RS16680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMD17_RS16685	COG4771	TonB-dependent receptor
AMD17_RS16690	COG2827	Endonuclease containing a URI domain
AMD17_RS16730	COG1877	trehalose-phosphatase activity
AMD17_RS16735	COG3387	PFAM Glycoside hydrolase 15-related
AMD17_RS16750	COG0840	transmembrane signaling receptor activity
AMD17_RS16755	COG3011	Protein conserved in bacteria
AMD17_RS16770	COG0564	pseudouridine synthase activity
AMD17_RS16775	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMD17_RS16785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMD17_RS16785	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AMD17_RS16815	COG2951	lytic endotransglycosylase activity
AMD17_RS16820	COG4644	lycopene metabolic process
AMD17_RS16840	COG2369	cell adhesion
AMD17_RS16860	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AMD17_RS16865	COG0045	succinate-CoA ligase (ADP-forming) activity
AMD17_RS16880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMD17_RS16910	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AMD17_RS16915	COG0237	dephospho-CoA kinase activity
AMD17_RS16935	COG2801	Transposase and inactivated derivatives
AMD17_RS16940	COG5002	protein histidine kinase activity
AMD17_RS16945	COG0745	RESPONSE REGULATOR receiver
AMD17_RS16955	COG0189	ligase activity
AMD17_RS17015	COG2003	Belongs to the UPF0758 family
AMD17_RS17040	COG4191	Histidine kinase
AMD17_RS17040	COG0784	Response regulator, receiver
AMD17_RS17045	COG0784	Response regulator, receiver
AMD17_RS17045	COG4191	Histidine kinase
AMD17_RS17155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AMD17_RS17180	COG2022	thiamine diphosphate biosynthetic process
AMD17_RS17185	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AMD17_RS17190	COG3273	potassium ion transport
AMD17_RS17190	COG0471	metal ion transport
AMD17_RS17210	COG1970	mechanosensitive ion channel activity
AMD17_RS17235	COG3250	beta-galactosidase activity
AMD17_RS17240	COG4948	Mandelate Racemase Muconate Lactonizing
AMD17_RS17255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMD17_RS17265	COG0308	aminopeptidase N
AMD17_RS17315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMD17_RS17325	COG2895	sulfate adenylyltransferase (ATP) activity
AMD17_RS17325	COG0529	Catalyzes the synthesis of activated sulfate
AMD17_RS17330	COG0175	sulfate reduction
AMD17_RS17335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AMD17_RS17340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMD17_RS17345	COG0175	sulfate reduction
AMD17_RS17365	COG0784	Response regulator, receiver
AMD17_RS17365	COG2198	Histidine kinase
AMD17_RS17365	COG2205	protein histidine kinase activity
AMD17_RS17400	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AMD17_RS17405	COG3588	fructose-bisphosphate aldolase
AMD17_RS17410	COG0469	pyruvate kinase activity
AMD17_RS17420	COG0126	phosphoglycerate kinase activity
AMD17_RS17440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AMD17_RS17450	COG3047	cAMP biosynthetic process
AMD17_RS17455	COG3047	cAMP biosynthetic process
AMD17_RS17465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMD17_RS17465	COG3453	Protein conserved in bacteria
AMD17_RS17470	COG0725	ABC transporter, periplasmic molybdate-binding protein
AMD17_RS17475	COG4149	molybdate abc transporter
AMD17_RS17480	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AMD17_RS17515	COG1376	ErfK ybiS ycfS ynhG family protein
AMD17_RS17520	COG0739	heme binding
AMD17_RS17530	COG4773	Receptor
AMD17_RS17550	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AMD17_RS17555	COG1301	dicarboxylic acid transport
AMD17_RS17565	COG2304	oxidoreductase activity
AMD17_RS17585	COG0714	Associated with various cellular activities
AMD17_RS17615	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMD17_RS17640	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AMD17_RS17650	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMD17_RS17660	COG0194	GDP metabolic process
AMD17_RS17665	COG1561	YicC-like family, N-terminal region
AMD17_RS17670	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AMD17_RS17680	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AMD17_RS17685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMD17_RS17700	COG0006	proline dipeptidase activity
AMD17_RS17710	COG0006	proline dipeptidase activity
AMD17_RS17715	COG3079	Belongs to the UPF0149 family
AMD17_RS17730	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AMD17_RS17740	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AMD17_RS17750	COG2912	Transglutaminase-like superfamily
AMD17_RS17755	COG1773	rubredoxin
AMD17_RS17760	COG0352	thiamine-phosphate diphosphorylase activity
AMD17_RS17775	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AMD17_RS17790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMD17_RS17820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMD17_RS17825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMD17_RS17830	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS17840	COG0671	phosphoesterase, PA-phosphatase related
AMD17_RS17845	COG3781	membrane
AMD17_RS17855	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMD17_RS17860	COG0563	adenylate kinase activity
AMD17_RS17875	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AMD17_RS17885	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AMD17_RS17905	COG3710	Transcriptional regulator
AMD17_RS17910	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AMD17_RS17920	COG0840	transmembrane signaling receptor activity
AMD17_RS17925	COG0405	Gamma-glutamyltransferase
AMD17_RS17930	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AMD17_RS17950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMD17_RS17955	COG0473	3-isopropylmalate dehydrogenase activity
AMD17_RS17960	COG0066	3-isopropylmalate dehydratase activity
AMD17_RS17965	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AMD17_RS17985	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AMD17_RS17990	COG1538	Outer membrane efflux protein
AMD17_RS17995	COG1519	Transferase
AMD17_RS18000	COG1560	Kdo2-lipid A biosynthetic process
AMD17_RS18025	COG0281	malic enzyme
AMD17_RS18025	COG0280	phosphate acetyltransferase
AMD17_RS18030	COG1301	dicarboxylic acid transport
AMD17_RS18055	COG0583	DNA-binding transcription factor activity
AMD17_RS18060	COG0667	Aldo Keto reductase
AMD17_RS18075	COG2197	response regulator
AMD17_RS18085	COG0642	Histidine kinase
AMD17_RS18100	COG2851	Citrate transporter
AMD17_RS18105	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS18110	COG1609	Transcriptional regulator
AMD17_RS18115	COG2211	Major facilitator Superfamily
AMD17_RS18140	COG1162	GTPase activity
AMD17_RS18160	COG4773	Receptor
AMD17_RS18165	COG0726	polysaccharide deacetylase
AMD17_RS18170	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AMD17_RS18185	COG2963	transposase activity
AMD17_RS18190	COG2801	Transposase and inactivated derivatives
AMD17_RS18205	COG1307	EDD domain protein, DegV family
AMD17_RS18210	COG0242	peptide deformylase activity
AMD17_RS18230	COG0457	Tetratricopeptide repeat
AMD17_RS18235	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AMD17_RS18240	COG1215	transferase activity, transferring glycosyl groups
AMD17_RS18245	COG1215	transferase activity, transferring glycosyl groups
AMD17_RS18260	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AMD17_RS18315	COG2188	Transcriptional regulator
AMD17_RS18325	COG1450	Type ii and iii secretion system protein
AMD17_RS18340	COG3166	PFAM Fimbrial assembly family protein
AMD17_RS18345	COG3156	type II secretion system protein K
AMD17_RS18350	COG4795	General secretion pathway protein
AMD17_RS18355	COG2165	general secretion pathway protein
AMD17_RS18360	COG4970	Tfp pilus assembly protein FimT
AMD17_RS18365	COG2165	general secretion pathway protein
AMD17_RS18370	COG1459	type II secretion system
AMD17_RS18375	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMD17_RS18380	COG1404	Belongs to the peptidase S8 family
AMD17_RS18385	COG5295	Hep Hag repeat protein
AMD17_RS18390	COG1404	Belongs to the peptidase S8 family
AMD17_RS18395	COG5295	Hep Hag repeat protein
AMD17_RS18405	COG0047	phosphoribosylformylglycinamidine synthase activity
AMD17_RS18405	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMD17_RS18410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMD17_RS18415	COG4974	Belongs to the 'phage' integrase family
AMD17_RS18430	COG0795	lipopolysaccharide-transporting ATPase activity
AMD17_RS18440	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMD17_RS18455	COG0525	valine-tRNA ligase activity
AMD17_RS18485	COG1183	phosphatidylcholine synthase activity
AMD17_RS18495	COG0442	prolyl-tRNA aminoacylation
AMD17_RS18510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMD17_RS18515	COG1127	ABC transporter
AMD17_RS18520	COG3218	ABC-type transport auxiliary lipoprotein component
AMD17_RS18520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMD17_RS18555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMD17_RS18560	COG0662	Cupin 2, conserved barrel domain protein
AMD17_RS18560	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AMD17_RS18590	COG2086	electron transfer activity
AMD17_RS18605	COG0546	phosphoglycolate phosphatase activity
AMD17_RS18605	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AMD17_RS18610	COG0277	FAD linked oxidase domain protein
AMD17_RS18625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMD17_RS18655	COG0438	transferase activity, transferring glycosyl groups
AMD17_RS18655	COG1216	Glycosyl transferase, family 2
AMD17_RS18675	COG0626	cystathionine gamma-synthase activity
AMD17_RS18710	COG0625	glutathione transferase activity
AMD17_RS18720	COG0513	Belongs to the DEAD box helicase family
AMD17_RS18730	COG4206	TonB-dependent receptor
AMD17_RS18735	COG0720	synthase
AMD17_RS18745	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AMD17_RS18755	COG1956	GAF domain-containing protein
AMD17_RS18765	COG2819	hydrolase of the alpha beta superfamily
AMD17_RS18780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMD17_RS18785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMD17_RS18800	COG0339	signal peptide processing
AMD17_RS18850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMD17_RS18855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMD17_RS18860	COG4591	ABC-type transport system involved in lipoprotein release permease component
AMD17_RS18860	COG1136	(ABC) transporter
AMD17_RS18865	COG0577	efflux transmembrane transporter activity
AMD17_RS18865	COG1136	(ABC) transporter
AMD17_RS18870	COG0577	efflux transmembrane transporter activity
AMD17_RS18885	COG4191	Histidine kinase
AMD17_RS18890	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AMD17_RS18905	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AMD17_RS18910	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AMD17_RS18915	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AMD17_RS18920	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AMD17_RS18925	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMD17_RS18930	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMD17_RS18940	COG0356	it plays a direct role in the translocation of protons across the membrane
AMD17_RS18960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMD17_RS18970	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMD17_RS19015	COG2011	ABC-type metal ion transport system permease component
AMD17_RS19020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AMD17_RS19025	COG0697	spore germination
AMD17_RS19030	COG1666	GTP binding
AMD17_RS19040	COG0784	Response regulator, receiver
AMD17_RS19040	COG2198	Histidine kinase
AMD17_RS19040	COG5002	protein histidine kinase activity
AMD17_RS19065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMD17_RS19070	COG1187	pseudouridine synthase activity
AMD17_RS19075	COG2813	Specifically methylates the guanine in position
AMD17_RS19095	COG2205	protein histidine kinase activity
AMD17_RS19095	COG2202	Pas domain
AMD17_RS19115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AMD17_RS19120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMD17_RS19175	COG0842	Transport permease protein
AMD17_RS19180	COG1131	(ABC) transporter
AMD17_RS19185	COG0025	NhaP-type Na H and K H
AMD17_RS19190	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AMD17_RS19195	COG1573	uracil-dna glycosylase
AMD17_RS19205	COG3384	dioxygenase
AMD17_RS19215	COG0583	DNA-binding transcription factor activity
AMD17_RS19225	COG0667	Aldo Keto reductase
AMD17_RS19235	COG3590	peptidase
AMD17_RS19255	COG0531	amino acid
AMD17_RS19270	COG2972	Histidine kinase
AMD17_RS19285	COG3685	Protein conserved in bacteria
AMD17_RS19290	COG3546	catalase activity
AMD17_RS19335	COG1271	oxidase subunit
AMD17_RS19340	COG1294	oxidase, subunit
AMD17_RS19355	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS19360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMD17_RS19380	COG1132	(ABC) transporter
AMD17_RS19395	COG1063	alcohol dehydrogenase
AMD17_RS19470	COG0251	oxidation-reduction process
AMD17_RS19500	COG0840	transmembrane signaling receptor activity
AMD17_RS19520	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AMD17_RS19560	COG0024	Methionine aminopeptidase
AMD17_RS19580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMD17_RS19585	COG1490	D-aminoacyl-tRNA deacylase activity
AMD17_RS19590	COG1560	Kdo2-lipid A biosynthetic process
AMD17_RS19640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMD17_RS19640	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMD17_RS19645	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMD17_RS19650	COG0242	peptide deformylase activity
AMD17_RS19655	COG1652	LysM domain
AMD17_RS19660	COG0758	DNA mediated transformation
AMD17_RS19665	COG2922	Belongs to the Smg family
AMD17_RS19680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AMD17_RS19680	COG1754	DNA topoisomerase type I activity
AMD17_RS19685	COG0009	L-threonylcarbamoyladenylate synthase
AMD17_RS19700	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS19710	COG0616	signal peptide processing
AMD17_RS19715	COG0534	Mate efflux family protein
AMD17_RS19735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AMD17_RS19740	COG0625	glutathione transferase activity
AMD17_RS19755	COG1252	NADH dehydrogenase
AMD17_RS19760	COG2860	membrane
AMD17_RS19765	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMD17_RS19770	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AMD17_RS19775	COG2201	protein-glutamate methylesterase activity
AMD17_RS19780	COG2177	Part of the ABC transporter FtsEX involved in
AMD17_RS19785	COG2884	Cell division ATP-binding protein ftsE
AMD17_RS19790	COG0513	Belongs to the DEAD box helicase family
AMD17_RS19795	COG3118	belongs to the thioredoxin family
AMD17_RS19800	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AMD17_RS19805	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AMD17_RS19810	COG0583	DNA-binding transcription factor activity
AMD17_RS19855	COG1518	maintenance of DNA repeat elements
AMD17_RS19860	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AMD17_RS19870	COG1652	LysM domain
AMD17_RS19875	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AMD17_RS19875	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AMD17_RS19880	COG1473	amidohydrolase
AMD17_RS19885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMD17_RS19890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMD17_RS19900	COG5383	Protein conserved in bacteria
AMD17_RS19940	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AMD17_RS19945	COG3023	N-Acetylmuramoyl-L-alanine amidase
AMD17_RS19955	COG4948	Mandelate Racemase Muconate Lactonizing
AMD17_RS19965	COG0531	amino acid
AMD17_RS19980	COG4682	membrane
AMD17_RS19985	COG2133	pyrroloquinoline quinone binding
AMD17_RS19995	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AMD17_RS20000	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AMD17_RS20010	COG1610	YqeY-like protein
AMD17_RS20015	COG1295	ribonuclease BN
AMD17_RS20020	COG0358	DNA primase activity
AMD17_RS20035	COG0109	protoheme IX farnesyltransferase activity
AMD17_RS20065	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AMD17_RS20075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMD17_RS20120	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AMD17_RS20125	COG0739	heme binding
AMD17_RS20130	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AMD17_RS20140	COG2223	nitrite transmembrane transporter activity
AMD17_RS20145	COG0708	Exodeoxyribonuclease III
AMD17_RS20150	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AMD17_RS20160	COG1192	Involved in chromosome partitioning
AMD17_RS20165	COG1475	DNA binding
AMD17_RS20180	COG0463	Glycosyl transferase, family 2
AMD17_RS20200	COG0756	dUTP diphosphatase activity
AMD17_RS20205	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AMD17_RS20210	COG2003	Belongs to the UPF0758 family
AMD17_RS20215	COG0018	arginyl-trna synthetase
AMD17_RS20230	COG4221	oxidoreductase activity
AMD17_RS20235	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMD17_RS20235	COG2755	lipolytic protein G-D-S-L family
AMD17_RS20245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMD17_RS20255	COG1166	arginine decarboxylase activity
AMD17_RS20260	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AMD17_RS20300	COG0606	chelatase, subunit chli
AMD17_RS20395	COG0606	chelatase, subunit chli
AMD17_RS20410	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AMD17_RS20445	COG1690	Belongs to the RtcB family
AMD17_RS20485	COG1090	epimerase
AMD17_RS20495	COG0642	Histidine kinase
AMD17_RS20515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMD17_RS20540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMD17_RS20545	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMD17_RS20560	COG0753	catalase activity
AMD17_RS20575	COG2197	response regulator
AMD17_RS20580	COG4585	Histidine kinase
AMD17_RS20585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMD17_RS20590	COG1136	(ABC) transporter
AMD17_RS20615	COG0697	spore germination
AMD17_RS20630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMD17_RS20635	COG0180	Tryptophanyl-tRNA synthetase
AMD17_RS20640	COG3237	CsbD-like
AMD17_RS20680	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AMD17_RS20695	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AMD17_RS20740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMD17_RS20760	COG1199	ATP-dependent helicase activity
AMD17_RS20775	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AMD17_RS20835	COG0625	glutathione transferase activity
AMD17_RS20875	COG4555	ABC transporter
AMD17_RS20885	COG1476	TRANSCRIPTIONal
AMD17_RS20930	COG0543	2 iron, 2 sulfur cluster binding
AMD17_RS20930	COG0633	Ferredoxin
AMD17_RS20935	COG1131	(ABC) transporter
AMD17_RS20940	COG0842	Transport permease protein
AMD17_RS20950	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AMD17_RS20980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMD17_RS20985	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMD17_RS20995	COG1042	CoA-binding domain protein
AMD17_RS20995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMD17_RS20995	COG0045	succinate-CoA ligase (ADP-forming) activity
AMD17_RS21000	COG2239	Acts as a magnesium transporter
AMD17_RS21005	COG3338	carbonate dehydratase activity
AMD17_RS21015	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AMD17_RS21020	COG3387	PFAM Glycoside hydrolase 15-related
AMD17_RS21035	COG3100	YcgL domain-containing protein
AMD17_RS21040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMD17_RS21050	COG0463	Glycosyl transferase, family 2
AMD17_RS21065	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS21105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMD17_RS21120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMD17_RS21145	COG0823	Involved in the tonB-independent uptake of proteins
AMD17_RS21145	COG1506	peptidase
AMD17_RS21145	COG4946	Tricorn protease homolog
AMD17_RS21160	COG0408	coproporphyrinogen oxidase activity
AMD17_RS21195	COG2815	serine threonine protein kinase
AMD17_RS21195	COG0515	serine threonine protein kinase
AMD17_RS21200	COG0631	protein serine/threonine phosphatase activity
AMD17_RS21360	COG0210	DNA helicase
AMD17_RS21375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMD17_RS21380	COG0583	DNA-binding transcription factor activity
AMD17_RS21385	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AMD17_RS21395	COG2159	amidohydrolase
AMD17_RS21415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMD17_RS21435	COG0357	Ribosomal RNA small subunit methyltransferase G
AMD17_RS21440	COG3540	Alkaline phosphatase
AMD17_RS21450	COG2091	lysine biosynthetic process via aminoadipic acid
AMD17_RS21470	COG0708	Exodeoxyribonuclease III
AMD17_RS21475	COG1940	carbohydrate kinase activity
AMD17_RS21475	COG1846	Transcriptional regulator
AMD17_RS21485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMD17_RS21495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMD17_RS21500	COG3162	membrane
AMD17_RS21510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMD17_RS21540	COG3507	Belongs to the glycosyl hydrolase 43 family
AMD17_RS21560	COG1028	Short-chain dehydrogenase reductase Sdr
AMD17_RS21565	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMD17_RS21570	COG4948	Mandelate Racemase Muconate Lactonizing
AMD17_RS21580	COG3254	rhamnose metabolic process
AMD17_RS21585	COG0738	Major facilitator superfamily
AMD17_RS21590	COG1414	Transcriptional regulator
AMD17_RS21595	COG1971	Probably functions as a manganese efflux pump
AMD17_RS21600	COG2205	protein histidine kinase activity
AMD17_RS21615	COG3459	Glycosyltransferase 36 associated
AMD17_RS21620	COG2211	Major facilitator Superfamily
AMD17_RS21625	COG3265	gluconokinase activity
AMD17_RS21630	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMD17_RS21650	COG2911	Protein conserved in bacteria
AMD17_RS21655	COG0729	surface antigen
AMD17_RS21695	COG0752	glycyl-tRNA synthetase alpha subunit
AMD17_RS21700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMD17_RS21710	COG0519	Catalyzes the synthesis of GMP from XMP
AMD17_RS21710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMD17_RS21720	COG0805	protein transport
AMD17_RS21725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMD17_RS21730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMD17_RS21740	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AMD17_RS21760	COG2974	May be involved in recombination
AMD17_RS21765	COG0037	tRNA processing
AMD17_RS21770	COG2115	Belongs to the xylose isomerase family
AMD17_RS21780	COG3661	Belongs to the glycosyl hydrolase 67 family
AMD17_RS21790	COG4948	Mandelate Racemase Muconate Lactonizing
AMD17_RS21800	COG1472	Belongs to the glycosyl hydrolase 3 family
AMD17_RS21805	COG0246	Mannitol dehydrogenase
AMD17_RS21880	COG3386	PFAM SMP-30 Gluconolaconase
AMD17_RS21890	COG3250	beta-galactosidase activity
AMD17_RS21895	COG1904	glucuronate isomerase
AMD17_RS21900	COG3693	PFAM glycoside hydrolase, family 10
AMD17_RS21915	COG3693	PFAM glycoside hydrolase, family 10
AMD17_RS21930	COG2211	Major facilitator Superfamily
AMD17_RS21975	COG2937	Belongs to the GPAT DAPAT family
AMD17_RS22010	COG0284	orotidine-5'-phosphate decarboxylase activity
AMD17_RS22015	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AMD17_RS22020	COG3132	Protein of unknown function, DUF480
AMD17_RS22035	COG0210	DNA helicase
AMD17_RS22040	COG1435	thymidine kinase activity
AMD17_RS22050	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AMD17_RS22060	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMD17_RS22095	COG3135	benzoate transporter
AMD17_RS22115	COG0676	glucose-6-phosphate 1-epimerase activity
AMD17_RS22125	COG3012	SEC-C Motif Domain Protein
AMD17_RS22130	COG0730	response to heat
AMD17_RS22150	COG0302	gtp cyclohydrolase
AMD17_RS22165	COG1566	PFAM secretion protein HlyD family protein
AMD17_RS22175	COG1289	transmembrane transporter activity
AMD17_RS22180	COG0477	Major facilitator Superfamily
AMD17_RS22190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMD17_RS22210	COG4691	Plasmid stability protein
AMD17_RS22215	COG1487	ribonuclease activity
AMD17_RS22240	COG0564	pseudouridine synthase activity
AMD17_RS22275	COG0439	Biotin carboxylase
AMD17_RS22315	COG1074	ATP-dependent DNA helicase activity
AMD17_RS22320	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AMD17_RS22335	COG1127	ABC transporter
AMD17_RS22340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMD17_RS22345	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMD17_RS22360	COG2853	Lipoprotein
AMD17_RS22370	COG0386	Belongs to the glutathione peroxidase family
AMD17_RS22380	COG1322	Protein conserved in bacteria
AMD17_RS22385	COG0604	alcohol dehydrogenase
AMD17_RS22400	COG0625	glutathione transferase activity
AMD17_RS22410	COG0531	amino acid
AMD17_RS22415	COG3537	Alpha-1,2-mannosidase
AMD17_RS22425	COG3706	GGDEF domain
AMD17_RS22430	COG3835	regulator
AMD17_RS22435	COG1929	Belongs to the glycerate kinase type-1 family
AMD17_RS22440	COG2271	Major facilitator Superfamily
AMD17_RS22455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AMD17_RS22460	COG0861	Integral membrane protein TerC family
AMD17_RS22470	COG0584	glycerophosphoryl diester phosphodiesterase
AMD17_RS22485	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AMD17_RS22490	COG0726	polysaccharide deacetylase
AMD17_RS22500	COG0706	membrane insertase activity
AMD17_RS22505	COG0594	ribonuclease P activity