locus-tag	class	description
J151_RS00325	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
J151_RS00370	COG0493	'glutamate synthase
J151_RS00385	COG0070	glutamate synthase
J151_RS00385	COG0069	glutamate synthase activity
J151_RS00385	COG0067	glutamate synthase
J151_RS00395	COG0067	glutamate synthase
J151_RS00395	COG0070	glutamate synthase
J151_RS00395	COG0069	glutamate synthase activity
J151_RS00495	COG0367	asparagine synthase
J151_RS00515	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J151_RS00525	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J151_RS00530	COG0187	DNA topoisomerase II activity
J151_RS00540	COG0501	Belongs to the peptidase M48B family
J151_RS00570	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J151_RS00580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J151_RS00625	COG0793	Belongs to the peptidase S41A family
J151_RS00630	COG4942	peptidase
J151_RS00640	COG2234	aminopeptidase activity
J151_RS00650	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
J151_RS00655	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
J151_RS00665	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
J151_RS00670	COG1064	alcohol dehydrogenase
J151_RS00675	COG0493	'glutamate synthase
J151_RS00680	COG0069	glutamate synthase activity
J151_RS00680	COG0067	glutamate synthase
J151_RS00680	COG0070	glutamate synthase
J151_RS00725	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J151_RS00740	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J151_RS00745	COG0297	glycogen (starch) synthase activity
J151_RS00745	COG0438	transferase activity, transferring glycosyl groups
J151_RS00765	COG0367	asparagine synthase
J151_RS00795	COG1132	(ABC) transporter
J151_RS00825	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J151_RS00910	COG1111	helicase
J151_RS00910	COG1205	dead DEAH box helicase
J151_RS00915	COG1272	protein, Hemolysin III
J151_RS00930	COG0300	oxidoreductase activity
J151_RS00935	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS00955	COG2249	NAD(P)H dehydrogenase (quinone) activity
J151_RS01015	COG3237	CsbD-like
J151_RS01065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J151_RS01075	COG0477	Major facilitator Superfamily
J151_RS01115	COG0714	Associated with various cellular activities
J151_RS01145	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
J151_RS01155	COG4772	TonB-dependent receptor
J151_RS01165	COG0662	Cupin 2, conserved barrel domain protein
J151_RS01170	COG1012	belongs to the aldehyde dehydrogenase family
J151_RS01195	COG1304	FMN binding
J151_RS01205	COG4585	Histidine kinase
J151_RS01210	COG2197	response regulator
J151_RS01230	COG3710	Transcriptional regulator
J151_RS01235	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J151_RS01305	COG2801	Transposase and inactivated derivatives
J151_RS01310	COG0366	Alpha amylase catalytic
J151_RS01315	COG0366	Alpha amylase catalytic
J151_RS01320	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J151_RS01340	COG2755	lipolytic protein G-D-S-L family
J151_RS01340	COG0657	acetylesterase activity
J151_RS01350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J151_RS01365	COG3507	Belongs to the glycosyl hydrolase 43 family
J151_RS01370	COG1609	Transcriptional regulator
J151_RS01375	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
J151_RS01380	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS01390	COG2755	lipolytic protein G-D-S-L family
J151_RS01405	COG3186	Phenylalanine-4-hydroxylase
J151_RS01410	COG1522	sequence-specific DNA binding
J151_RS01420	COG1752	Esterase of the alpha-beta hydrolase superfamily
J151_RS01430	COG1119	ATPase activity
J151_RS01445	COG1125	glycine betaine transport
J151_RS01460	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J151_RS01480	COG1396	sequence-specific DNA binding
J151_RS01505	COG0489	protein tyrosine kinase activity
J151_RS01510	COG2062	phosphohistidine phosphatase, SixA
J151_RS01520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J151_RS01565	COG1968	undecaprenyl-diphosphatase activity
J151_RS01570	COG0174	glutamine synthetase
J151_RS01575	COG0347	Belongs to the P(II) protein family
J151_RS01580	COG0004	ammonium transporteR
J151_RS01585	COG3852	Histidine kinase
J151_RS01590	COG2204	response regulator
J151_RS01595	COG2032	superoxide dismutase activity
J151_RS01600	COG2032	superoxide dismutase activity
J151_RS01605	COG0346	lactoylglutathione lyase activity
J151_RS01615	COG0183	Belongs to the thiolase family
J151_RS01650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J151_RS01655	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
J151_RS01660	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J151_RS01670	COG0028	Belongs to the TPP enzyme family
J151_RS01675	COG2205	protein histidine kinase activity
J151_RS01700	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J151_RS01715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J151_RS01725	COG0596	Alpha beta hydrolase
J151_RS01730	COG0727	PFAM Uncharacterised protein family (UPF0153)
J151_RS01735	COG0318	PFAM AMP-dependent synthetase and ligase
J151_RS01740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J151_RS01750	COG1181	Belongs to the D-alanine--D-alanine ligase family
J151_RS01760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J151_RS01770	COG0564	pseudouridine synthase activity
J151_RS01795	COG0339	signal peptide processing
J151_RS01825	COG0475	glutathione-regulated potassium exporter activity
J151_RS01830	COG0583	DNA-binding transcription factor activity
J151_RS01835	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J151_RS01840	COG2224	Isocitrate lyase
J151_RS01870	COG4770	biotin carboxylase activity
J151_RS01875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J151_RS01880	COG1960	acyl-CoA dehydrogenase activity
J151_RS01935	COG0523	cobalamin synthesis protein
J151_RS01950	COG0697	spore germination
J151_RS01960	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J151_RS01965	COG1846	Transcriptional regulator
J151_RS01970	COG1764	response to oxidative stress
J151_RS02000	COG2130	NADP-dependent
J151_RS02015	COG1187	pseudouridine synthase activity
J151_RS02030	COG1643	Atp-dependent helicase
J151_RS02040	COG4807	Protein conserved in bacteria
J151_RS02045	COG2351	hydroxyisourate hydrolase activity
J151_RS02050	COG2072	flavoprotein involved in K transport
J151_RS02070	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J151_RS02105	COG1957	nucleoside hydrolase
J151_RS02115	COG2252	PERMEase
J151_RS02140	COG0084	hydrolase, TatD family'
J151_RS02155	COG0583	DNA-binding transcription factor activity
J151_RS02160	COG2814	Major facilitator Superfamily
J151_RS02175	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J151_RS02180	COG1902	pentaerythritol trinitrate reductase activity
J151_RS02200	COG0745	RESPONSE REGULATOR receiver
J151_RS02205	COG2205	protein histidine kinase activity
J151_RS02210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J151_RS02230	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J151_RS02235	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J151_RS02240	COG0583	DNA-binding transcription factor activity
J151_RS02275	COG0702	epimerase
J151_RS02280	COG1733	regulation of RNA biosynthetic process
J151_RS02305	COG2801	Transposase and inactivated derivatives
J151_RS02320	COG0129	dihydroxy-acid dehydratase activity
J151_RS02340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J151_RS02395	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J151_RS02400	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J151_RS02425	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J151_RS02430	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J151_RS02440	COG3485	protocatechuate 3,4-dioxygenase
J151_RS02445	COG3485	protocatechuate 3,4-dioxygenase
J151_RS02455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J151_RS02460	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J151_RS02470	COG1414	Transcriptional regulator
J151_RS02480	COG0657	acetylesterase activity
J151_RS02490	COG0445	tRNA wobble uridine modification
J151_RS02500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J151_RS02530	COG2267	carboxylic ester hydrolase activity
J151_RS02540	COG0156	8-amino-7-oxononanoate synthase activity
J151_RS02545	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J151_RS02550	COG1040	competence protein
J151_RS02555	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J151_RS02630	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J151_RS02700	COG1511	domain protein
J151_RS02700	COG3264	Mechanosensitive ion channel
J151_RS02705	COG1368	sulfuric ester hydrolase activity
J151_RS02710	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J151_RS02715	COG2354	Protein conserved in bacteria
J151_RS02725	COG0297	glycogen (starch) synthase activity
J151_RS02730	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J151_RS02735	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J151_RS02760	COG0702	epimerase
J151_RS02765	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS02800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J151_RS02805	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS02815	COG0513	Belongs to the DEAD box helicase family
J151_RS02835	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J151_RS02845	COG3483	tryptophan 2,3-dioxygenase activity
J151_RS02850	COG3104	oligopeptide transport
J151_RS02870	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J151_RS02885	COG1320	monovalent cation:proton antiporter activity
J151_RS02890	COG2212	antiporter activity
J151_RS02900	COG0651	ATP synthesis coupled electron transport
J151_RS02905	COG1006	Multisubunit Na H antiporter MnhC subunit
J151_RS02910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J151_RS02910	COG2111	Na H antiporter
J151_RS02930	COG3179	chitinase
J151_RS02950	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J151_RS02955	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J151_RS02970	COG0456	acetyltransferase
J151_RS02975	COG1597	lipid kinase activity
J151_RS03000	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J151_RS03005	COG0134	indole-3-glycerol-phosphate synthase activity
J151_RS03015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J151_RS03020	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
J151_RS03030	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
J151_RS03040	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J151_RS03055	COG1051	belongs to the nudix hydrolase family
J151_RS03095	COG0316	Belongs to the HesB IscA family
J151_RS03120	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
J151_RS03140	COG2814	Major facilitator Superfamily
J151_RS03145	COG0583	DNA-binding transcription factor activity
J151_RS03150	COG2814	Major facilitator Superfamily
J151_RS03155	COG1289	transmembrane transporter activity
J151_RS03165	COG0151	Belongs to the GarS family
J151_RS03175	COG0138	bifunctional purine biosynthesis protein purh
J151_RS03180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J151_RS03185	COG2267	carboxylic ester hydrolase activity
J151_RS03190	COG0671	phosphoesterase, PA-phosphatase related
J151_RS03190	COG2453	phosphatase
J151_RS03215	COG4589	Belongs to the CDS family
J151_RS03220	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J151_RS03245	COG2264	protein methyltransferase activity
J151_RS03260	COG0439	Biotin carboxylase
J151_RS03270	COG0511	ligase activity, forming carbon-carbon bonds
J151_RS03275	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J151_RS03285	COG1324	tolerance protein
J151_RS03310	COG0300	oxidoreductase activity
J151_RS03315	COG2356	endonuclease I
J151_RS03325	COG0459	protein refolding
J151_RS03340	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J151_RS03355	COG3386	PFAM SMP-30 Gluconolaconase
J151_RS03365	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J151_RS03370	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J151_RS03390	COG0778	Nitroreductase
J151_RS03395	COG2353	YceI-like domain
J151_RS03425	COG3052	prosthetic group binding
J151_RS03450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J151_RS03460	COG1802	Transcriptional regulator
J151_RS03505	COG2801	Transposase and inactivated derivatives
J151_RS03515	COG4221	oxidoreductase activity
J151_RS03530	COG4221	oxidoreductase activity
J151_RS03540	COG0435	Glutathione S-transferase
J151_RS03565	COG2409	Drug exporters of the RND superfamily
J151_RS03570	COG0823	Involved in the tonB-independent uptake of proteins
J151_RS03570	COG1506	peptidase
J151_RS03610	COG0697	spore germination
J151_RS03625	COG1113	amino acid transport
J151_RS03645	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
J151_RS03680	COG5001	Diguanylate cyclase
J151_RS03685	COG0840	transmembrane signaling receptor activity
J151_RS03690	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
J151_RS03690	COG5297	Belongs to the glycosyl hydrolase family 6
J151_RS03695	COG0659	secondary active sulfate transmembrane transporter activity
J151_RS03715	COG2943	transferase activity, transferring hexosyl groups
J151_RS03725	COG3275	phosphorelay sensor kinase activity
J151_RS03735	COG0181	hydroxymethylbilane synthase activity
J151_RS03760	COG1505	serine-type exopeptidase activity
J151_RS03765	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J151_RS03770	COG0436	Aminotransferase
J151_RS03780	COG2832	Protein of unknown function (DUF454)
J151_RS03790	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J151_RS03800	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J151_RS03805	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J151_RS03810	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J151_RS03835	COG2226	methyltransferase
J151_RS03840	COG3300	MHYT domain
J151_RS03840	COG5001	Diguanylate cyclase
J151_RS03845	COG0308	aminopeptidase N
J151_RS03895	COG3284	Transcriptional regulator
J151_RS03900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J151_RS03905	COG1077	Cell shape determining protein MreB Mrl
J151_RS03910	COG1792	Involved in formation and maintenance of cell shape
J151_RS03925	COG0772	Belongs to the SEDS family
J151_RS03935	COG2951	lytic endotransglycosylase activity
J151_RS03940	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J151_RS03950	COG1686	Belongs to the peptidase S11 family
J151_RS03960	COG2921	Belongs to the UPF0250 family
J151_RS03965	COG0321	lipoyl(octanoyl) transferase activity
J151_RS03970	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J151_RS03985	COG0583	DNA-binding transcription factor activity
J151_RS03995	COG1056	cytidyltransferase-related domain
J151_RS03995	COG1051	belongs to the nudix hydrolase family
J151_RS04030	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
J151_RS04035	COG0673	inositol 2-dehydrogenase activity
J151_RS04040	COG2823	Periplasmic or secreted lipoprotein
J151_RS04045	COG4251	negative regulation of phosphorylation
J151_RS04050	COG0784	Response regulator, receiver
J151_RS04055	COG4191	Histidine kinase
J151_RS04060	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J151_RS04115	COG1459	type II secretion system
J151_RS04180	COG2188	Transcriptional regulator
J151_RS04190	COG1609	Transcriptional regulator
J151_RS04195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J151_RS04200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J151_RS04210	COG0617	tRNA 3'-terminal CCA addition
J151_RS04215	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
J151_RS04220	COG1012	belongs to the aldehyde dehydrogenase family
J151_RS04225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J151_RS04235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J151_RS04250	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J151_RS04255	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J151_RS04270	COG2205	protein histidine kinase activity
J151_RS04300	COG3791	Glutathione-dependent formaldehyde-activating
J151_RS04315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J151_RS04325	COG0697	spore germination
J151_RS04335	COG0488	(ABC) transporter
J151_RS04345	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J151_RS04350	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J151_RS04360	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J151_RS04360	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J151_RS04380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J151_RS04385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J151_RS04390	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J151_RS04410	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J151_RS04415	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
J151_RS04420	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
J151_RS04425	COG2205	protein histidine kinase activity
J151_RS04430	COG0745	RESPONSE REGULATOR receiver
J151_RS04445	COG0277	FAD linked oxidase domain protein
J151_RS04450	COG1988	membrane-bound metal-dependent
J151_RS04455	COG0792	nuclease activity
J151_RS04485	COG0275	rRNA processing
J151_RS04490	COG3116	cell division
J151_RS04500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J151_RS04505	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J151_RS04510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J151_RS04520	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J151_RS04525	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J151_RS04530	COG1181	Belongs to the D-alanine--D-alanine ligase family
J151_RS04535	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J151_RS04550	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J151_RS04560	COG0739	heme binding
J151_RS04565	COG0653	protein targeting
J151_RS04570	COG0494	nUDIX hydrolase
J151_RS04580	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J151_RS04590	COG0604	alcohol dehydrogenase
J151_RS04590	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS04590	COG3321	synthase
J151_RS04610	COG0366	Alpha amylase catalytic
J151_RS04640	COG2226	methyltransferase
J151_RS04645	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J151_RS04655	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J151_RS04690	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J151_RS04700	COG4106	trans-aconitate 2-methyltransferase activity
J151_RS04705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J151_RS04715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J151_RS04720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J151_RS04725	COG0667	Aldo Keto reductase
J151_RS04735	COG4771	TonB-dependent receptor
J151_RS04755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J151_RS04760	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
J151_RS04770	COG2175	clavaminate synthase activity
J151_RS04780	COG4181	ATPase activity
J151_RS04795	COG0642	Histidine kinase
J151_RS04805	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J151_RS04825	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J151_RS04830	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J151_RS04845	COG3829	transcription factor binding
J151_RS04855	COG1116	anion transmembrane transporter activity
J151_RS04860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J151_RS04870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J151_RS04875	COG0431	NADPH-dependent FMN reductase
J151_RS04900	COG0747	negative chemotaxis
J151_RS04910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J151_RS04920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J151_RS04925	COG2967	ApaG domain
J151_RS04930	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J151_RS04935	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J151_RS04940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J151_RS04945	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J151_RS04955	COG0123	including yeast histone deacetylase and acetoin utilization protein
J151_RS04960	COG2096	Adenosyltransferase
J151_RS04970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J151_RS04975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J151_RS05005	COG3384	dioxygenase
J151_RS05010	COG0583	DNA-binding transcription factor activity
J151_RS05025	COG1024	Enoyl-CoA hydratase
J151_RS05045	COG3386	PFAM SMP-30 Gluconolaconase
J151_RS05055	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
J151_RS05080	COG0697	spore germination
J151_RS05090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J151_RS05110	COG5002	protein histidine kinase activity
J151_RS05110	COG0784	Response regulator, receiver
J151_RS05110	COG2205	protein histidine kinase activity
J151_RS05115	COG2197	response regulator
J151_RS05125	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J151_RS05135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J151_RS05140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J151_RS05145	COG0583	DNA-binding transcription factor activity
J151_RS05150	COG3634	alkyl hydroperoxide reductase activity
J151_RS05160	COG2890	protein-(glutamine-N5) methyltransferase activity
J151_RS05180	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J151_RS05180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J151_RS05210	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J151_RS05240	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J151_RS05255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J151_RS05260	COG1404	Belongs to the peptidase S8 family
J151_RS05265	COG1404	Belongs to the peptidase S8 family
J151_RS05270	COG1404	Belongs to the peptidase S8 family
J151_RS05275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J151_RS05300	COG1295	ribonuclease BN
J151_RS05305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J151_RS05310	COG1254	Belongs to the acylphosphatase family
J151_RS05325	COG0521	Mo-molybdopterin cofactor biosynthetic process
J151_RS05335	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J151_RS05340	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J151_RS05350	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J151_RS05355	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J151_RS05365	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J151_RS05370	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J151_RS05375	COG0193	aminoacyl-tRNA hydrolase activity
J151_RS05380	COG0012	GTP binding
J151_RS05400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J151_RS05415	COG0250	Participates in transcription elongation, termination and antitermination
J151_RS05420	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J151_RS05425	COG0081	regulation of translation
J151_RS05430	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J151_RS05435	COG0222	ribosome binding
J151_RS05440	COG0085	RNA polymerase activity
J151_RS05445	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J151_RS05450	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J151_RS05455	COG0049	tRNA binding
J151_RS05460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J151_RS05465	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J151_RS05470	COG0051	transcription antitermination factor activity, RNA binding
J151_RS05475	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J151_RS05480	COG0088	Forms part of the polypeptide exit tunnel
J151_RS05485	COG0089	rRNA binding
J151_RS05490	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J151_RS05495	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J151_RS05505	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J151_RS05510	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J151_RS05515	COG0255	Belongs to the universal ribosomal protein uL29 family
J151_RS05520	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J151_RS05530	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J151_RS05535	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J151_RS05545	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J151_RS05550	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J151_RS05555	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J151_RS05565	COG1841	ribosomal large subunit assembly
J151_RS05570	COG0200	Binds to the 23S rRNA
J151_RS05575	COG0201	protein transport
J151_RS05600	COG0203	ribosomal protein L17
J151_RS05605	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J151_RS05620	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
J151_RS05630	COG0154	amidase activity
J151_RS05640	COG1217	gtp-binding protein TYPA
J151_RS05645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J151_RS05650	COG0039	L-malate dehydrogenase activity
J151_RS05655	COG0625	glutathione transferase activity
J151_RS05665	COG0446	pyridine nucleotide-disulphide oxidoreductase
J151_RS05665	COG1902	pentaerythritol trinitrate reductase activity
J151_RS05670	COG0604	alcohol dehydrogenase
J151_RS05695	COG0156	8-amino-7-oxononanoate synthase activity
J151_RS05700	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J151_RS05705	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J151_RS05710	COG4208	sulfate ABC transporter
J151_RS05715	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J151_RS05725	COG1063	alcohol dehydrogenase
J151_RS05755	COG0406	alpha-ribazole phosphatase activity
J151_RS05760	COG0285	dihydrofolate synthase activity
J151_RS05780	COG2833	Protein of unknown function (DUF455)
J151_RS05790	COG3291	Pkd domain containing protein
J151_RS05800	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J151_RS05805	COG0671	phosphoesterase, PA-phosphatase related
J151_RS05810	COG0438	transferase activity, transferring glycosyl groups
J151_RS05820	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J151_RS05835	COG4783	chaperone-mediated protein folding
J151_RS05850	COG0473	3-isopropylmalate dehydrogenase activity
J151_RS05980	COG2801	Transposase and inactivated derivatives
J151_RS05995	COG3852	Histidine kinase
J151_RS06005	COG0544	peptidyl-prolyl cis-trans isomerase activity
J151_RS06015	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J151_RS06045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J151_RS06055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J151_RS06065	COG0328	RNA-DNA hybrid ribonuclease activity
J151_RS06070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J151_RS06075	COG0631	protein serine/threonine phosphatase activity
J151_RS06090	COG0859	PFAM glycosyl transferase family 9
J151_RS06095	COG3642	lipopolysaccharide core region biosynthetic process
J151_RS06100	COG1234	tRNA 3'-trailer cleavage
J151_RS06105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J151_RS06115	COG0315	cyclic pyranopterin monophosphate synthase activity
J151_RS06120	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J151_RS06125	COG0314	molybdopterin synthase activity
J151_RS06180	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J151_RS06185	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J151_RS06190	COG0537	adenosine 5'-monophosphoramidase activity
J151_RS06210	COG0714	Associated with various cellular activities
J151_RS06230	COG0424	maF-like protein
J151_RS06235	COG1399	metal-binding, possibly nucleic acid-binding protein
J151_RS06240	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J151_RS06245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J151_RS06260	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS06275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J151_RS06280	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J151_RS06305	COG3829	transcription factor binding
J151_RS06325	COG3609	addiction module antidote protein, CC2985 family
J151_RS06345	COG2373	Large extracellular alpha-helical protein
J151_RS06360	COG4953	penicillin-binding protein 1C
J151_RS06370	COG0678	peroxiredoxin activity
J151_RS06390	COG0330	HflC and HflK could
J151_RS06395	COG0330	HflC and HflK could
J151_RS06405	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J151_RS06410	COG0308	aminopeptidase N
J151_RS06420	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS06425	COG1309	transcriptional regulator
J151_RS06495	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J151_RS06505	COG3387	PFAM Glycoside hydrolase 15-related
J151_RS06510	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS06515	COG3537	Alpha-1,2-mannosidase
J151_RS06535	COG0492	ferredoxin-NADP+ reductase activity
J151_RS06560	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J151_RS06565	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
J151_RS06570	COG2080	2 iron, 2 sulfur cluster binding
J151_RS06605	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J151_RS06620	COG0587	DNA-directed DNA polymerase activity
J151_RS06635	COG1297	OPT oligopeptide transporter protein
J151_RS06650	COG0823	Involved in the tonB-independent uptake of proteins
J151_RS06650	COG1506	peptidase
J151_RS06665	COG2207	Transcriptional regulator
J151_RS06665	COG1917	Cupin 2, conserved barrel domain protein
J151_RS06680	COG0753	catalase activity
J151_RS06685	COG0656	L-ascorbic acid biosynthetic process
J151_RS06695	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J151_RS06695	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J151_RS06700	COG2814	Major facilitator Superfamily
J151_RS06715	COG2194	sulfuric ester hydrolase activity
J151_RS06730	COG0745	RESPONSE REGULATOR receiver
J151_RS06735	COG0642	Histidine kinase
J151_RS06745	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J151_RS06750	COG2894	cell division
J151_RS06755	COG0850	regulation of cytokinetic process
J151_RS06770	COG4585	Histidine kinase
J151_RS06775	COG2197	response regulator
J151_RS06790	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J151_RS06815	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J151_RS06825	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J151_RS06845	COG1946	Acyl-CoA thioesterase
J151_RS06860	COG0824	Thioesterase
J151_RS06865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J151_RS06870	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J151_RS06875	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J151_RS06880	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J151_RS06885	COG0268	Binds directly to 16S ribosomal RNA
J151_RS06895	COG0196	riboflavin kinase activity
J151_RS06900	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J151_RS06905	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J151_RS06910	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J151_RS06925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J151_RS06930	COG1845	cytochrome c oxidase, subunit III
J151_RS06935	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J151_RS06950	COG3152	Membrane
J151_RS06960	COG2207	Transcriptional regulator
J151_RS06965	COG0326	Molecular chaperone. Has ATPase activity
J151_RS06975	COG1366	Belongs to the anti-sigma-factor antagonist family
J151_RS06980	COG1366	Belongs to the anti-sigma-factor antagonist family
J151_RS06985	COG2172	sigma factor antagonist activity
J151_RS07010	COG4771	TonB-dependent receptor
J151_RS07020	COG5507	3-demethylubiquinone-9 3-methyltransferase
J151_RS07025	COG2205	protein histidine kinase activity
J151_RS07035	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J151_RS07040	COG3850	Histidine kinase
J151_RS07040	COG2205	protein histidine kinase activity
J151_RS07040	COG3437	response regulator, receiver
J151_RS07040	COG4999	Histidine kinase
J151_RS07045	COG4191	Histidine kinase
J151_RS07045	COG0784	Response regulator, receiver
J151_RS07075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J151_RS07080	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J151_RS07095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J151_RS07100	COG0228	four-way junction DNA binding
J151_RS07105	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J151_RS07110	COG0336	Belongs to the RNA methyltransferase TrmD family
J151_RS07115	COG0335	large ribosomal subunit rRNA binding
J151_RS07145	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
J151_RS07155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J151_RS07165	COG3209	COG3209 Rhs family protein
J151_RS07185	COG3250	beta-galactosidase activity
J151_RS07190	COG3867	Arabinogalactan endo-beta-1,4-galactanase
J151_RS07210	COG1960	acyl-CoA dehydrogenase activity
J151_RS07215	COG1024	Enoyl-CoA hydratase
J151_RS07235	COG1024	Enoyl-CoA hydratase
J151_RS07235	COG1250	3-hydroxyacyl-CoA dehydrogenase
J151_RS07250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J151_RS07255	COG0481	GTPase activity
J151_RS07270	COG0571	ribonuclease III activity
J151_RS07275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J151_RS07280	COG1381	Involved in DNA repair and RecF pathway recombination
J151_RS07290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J151_RS07295	COG2954	triphosphatase activity
J151_RS07300	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J151_RS07305	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
J151_RS07310	COG3046	protein related to deoxyribodipyrimidine photolyase
J151_RS07315	COG1472	Belongs to the glycosyl hydrolase 3 family
J151_RS07320	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J151_RS07325	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
J151_RS07330	COG1278	Cold shock
J151_RS07335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J151_RS07345	COG1201	RNA secondary structure unwinding
J151_RS07350	COG1793	dna ligase
J151_RS07360	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J151_RS07360	COG1793	dna ligase
J151_RS07390	COG0183	Belongs to the thiolase family
J151_RS07410	COG1451	nucleotide metabolic process
J151_RS07415	COG5487	UPF0391 membrane protein
J151_RS07425	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J151_RS07445	COG1077	Cell shape determining protein MreB Mrl
J151_RS07450	COG1047	Peptidyl-prolyl cis-trans
J151_RS07460	COG2824	Alkylphosphonate utilization operon protein PhnA
J151_RS07465	COG1902	pentaerythritol trinitrate reductase activity
J151_RS07470	COG2814	Major facilitator Superfamily
J151_RS07505	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
J151_RS07505	COG0392	lysyltransferase activity
J151_RS07515	COG0251	oxidation-reduction process
J151_RS07520	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J151_RS07535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J151_RS07560	COG1595	DNA-templated transcription, initiation
J151_RS07580	COG2878	Part of a membrane complex involved in electron transport
J151_RS07590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J151_RS07590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J151_RS07605	COG1131	(ABC) transporter
J151_RS07610	COG0346	lactoylglutathione lyase activity
J151_RS07615	COG0833	amino acid
J151_RS07620	COG2040	homocysteine
J151_RS07630	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J151_RS07650	COG1695	Transcriptional regulator
J151_RS07670	COG1981	membrane
J151_RS07685	COG0825	malonyl-CoA metabolic process
J151_RS07695	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J151_RS07700	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J151_RS07705	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J151_RS07710	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J151_RS07715	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J151_RS07730	COG0750	zinc metalloprotease
J151_RS07735	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J151_RS07740	COG0575	Belongs to the CDS family
J151_RS07745	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J151_RS07750	COG0233	cytoplasmic translational termination
J151_RS07755	COG0528	UMP kinase activity
J151_RS07765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J151_RS07770	COG0052	Belongs to the universal ribosomal protein uS2 family
J151_RS07810	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J151_RS07820	COG1393	Belongs to the ArsC family
J151_RS07825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J151_RS07830	COG0367	asparagine synthase
J151_RS07840	COG4774	siderophore transport
J151_RS07860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J151_RS07890	COG1566	PFAM secretion protein HlyD family protein
J151_RS07895	COG2814	Major facilitator Superfamily
J151_RS07945	COG0339	signal peptide processing
J151_RS07950	COG0386	Belongs to the glutathione peroxidase family
J151_RS08005	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J151_RS08010	COG0084	hydrolase, TatD family'
J151_RS08025	COG1960	acyl-CoA dehydrogenase activity
J151_RS08045	COG0367	asparagine synthase
J151_RS08055	COG0305	Participates in initiation and elongation during chromosome replication
J151_RS08060	COG0415	Belongs to the DNA photolyase family
J151_RS08070	COG0583	DNA-binding transcription factor activity
J151_RS08115	COG3706	GGDEF domain
J151_RS08205	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J151_RS08220	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J151_RS08230	COG0497	DNA recombination
J151_RS08235	COG1420	regulation of RNA biosynthetic process
J151_RS08240	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J151_RS08245	COG0443	Heat shock 70 kDa protein
J151_RS08250	COG0484	heat shock protein binding
J151_RS08255	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J151_RS08285	COG0583	DNA-binding transcription factor activity
J151_RS08290	COG1132	(ABC) transporter
J151_RS08325	COG2850	peptidyl-arginine hydroxylation
J151_RS08345	COG1253	flavin adenine dinucleotide binding
J151_RS08375	COG1131	(ABC) transporter
J151_RS08380	COG1725	Transcriptional regulator
J151_RS08385	COG0386	Belongs to the glutathione peroxidase family
J151_RS08400	COG2900	Belongs to the SlyX family
J151_RS08425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J151_RS08435	COG0646	methionine synthase
J151_RS08435	COG1410	methionine synthase
J151_RS08440	COG0646	methionine synthase
J151_RS08440	COG1410	methionine synthase
J151_RS08445	COG2226	methyltransferase
J151_RS08450	COG1960	acyl-CoA dehydrogenase activity
J151_RS08465	COG0557	exoribonuclease II activity
J151_RS08475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J151_RS08485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J151_RS08495	COG0704	Plays a role in the regulation of phosphate uptake
J151_RS08500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J151_RS08505	COG0581	inorganic phosphate transmembrane transporter activity
J151_RS08510	COG0573	inorganic phosphate transmembrane transporter activity
J151_RS08515	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J151_RS08540	COG0659	secondary active sulfate transmembrane transporter activity
J151_RS08545	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J151_RS08555	COG1024	Enoyl-CoA hydratase
J151_RS08565	COG0494	nUDIX hydrolase
J151_RS08600	COG0488	(ABC) transporter
J151_RS08605	COG0116	Belongs to the methyltransferase superfamily
J151_RS08605	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J151_RS08610	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J151_RS08635	COG2925	Exonuclease
J151_RS08640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J151_RS08645	COG3844	kynureninase activity
J151_RS08655	COG0662	Cupin 2, conserved barrel domain protein
J151_RS08660	COG0288	reversible hydration of carbon dioxide
J151_RS08720	COG2808	Putative FMN-binding domain
J151_RS08740	COG0017	Asparaginyl-tRNA synthetase
J151_RS08745	COG0316	Belongs to the HesB IscA family
J151_RS08750	COG0360	Binds together with S18 to 16S ribosomal RNA
J151_RS08755	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J151_RS08760	COG0359	binds to the 23S rRNA
J151_RS08770	COG3115	cell septum assembly
J151_RS08780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J151_RS08785	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J151_RS08790	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J151_RS08800	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
J151_RS08820	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
J151_RS08830	COG2986	histidine ammonia-lyase
J151_RS08835	COG1228	amidohydrolase
J151_RS08880	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
J151_RS08885	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J151_RS08890	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J151_RS08895	COG0077	Prephenate dehydratase
J151_RS08895	COG1605	Chorismate mutase
J151_RS08900	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J151_RS08915	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J151_RS08920	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J151_RS08925	COG0583	DNA-binding transcription factor activity
J151_RS08960	COG2801	Transposase and inactivated derivatives
J151_RS08980	COG0840	transmembrane signaling receptor activity
J151_RS09015	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
J151_RS09020	COG4191	Histidine kinase
J151_RS09020	COG0784	Response regulator, receiver
J151_RS09035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J151_RS09045	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
J151_RS09055	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J151_RS09070	COG1595	DNA-templated transcription, initiation
J151_RS09125	COG2244	polysaccharide biosynthetic process
J151_RS09155	COG2264	protein methyltransferase activity
J151_RS09165	COG0438	transferase activity, transferring glycosyl groups
J151_RS09180	COG1136	(ABC) transporter
J151_RS09190	COG0477	Major facilitator Superfamily
J151_RS09195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J151_RS09210	COG1253	flavin adenine dinucleotide binding
J151_RS09220	COG0306	phosphate transporter
J151_RS09245	COG0504	CTP synthase activity
J151_RS09250	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J151_RS09260	COG0148	phosphopyruvate hydratase activity
J151_RS09265	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J151_RS09270	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J151_RS09275	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J151_RS09280	COG0585	pseudouridine synthase activity
J151_RS09285	COG2840	Smr protein MutS2
J151_RS09290	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J151_RS09295	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J151_RS09300	COG1238	metal cluster binding
J151_RS09315	COG1534	Rna-binding protein
J151_RS09320	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J151_RS09330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J151_RS09335	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J151_RS09345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J151_RS09350	COG1546	Belongs to the CinA family
J151_RS09360	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J151_RS09365	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J151_RS09370	COG2137	regulation of response to DNA damage stimulus
J151_RS09375	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J151_RS09380	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
J151_RS09395	COG1741	Belongs to the pirin family
J151_RS09405	COG0583	DNA-binding transcription factor activity
J151_RS09430	COG0352	thiamine-phosphate diphosphorylase activity
J151_RS09430	COG0351	phosphomethylpyrimidine kinase
J151_RS09445	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J151_RS09450	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J151_RS09465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J151_RS09475	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J151_RS09480	COG3734	2-keto-3-deoxy-galactonokinase
J151_RS09490	COG4948	Mandelate Racemase Muconate Lactonizing
J151_RS09495	COG0800	Aldolase
J151_RS09535	COG1501	Belongs to the glycosyl hydrolase 31 family
J151_RS09545	COG1070	Carbohydrate kinase
J151_RS09550	COG2115	Belongs to the xylose isomerase family
J151_RS09555	COG0477	Major facilitator Superfamily
J151_RS09565	COG0860	N-Acetylmuramoyl-L-alanine amidase
J151_RS09570	COG1469	GTP cyclohydrolase I activity
J151_RS09590	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J151_RS09595	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J151_RS09600	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
J151_RS09605	COG0166	Belongs to the GPI family
J151_RS09625	COG1472	Belongs to the glycosyl hydrolase 3 family
J151_RS09635	COG3706	GGDEF domain
J151_RS09635	COG5001	Diguanylate cyclase
J151_RS09635	COG2203	Gaf domain
J151_RS09635	COG4251	negative regulation of phosphorylation
J151_RS09640	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
J151_RS09645	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
J151_RS09655	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J151_RS09660	COG0671	phosphoesterase, PA-phosphatase related
J151_RS09670	COG1794	racemase activity, acting on amino acids and derivatives
J151_RS09675	COG0697	spore germination
J151_RS09680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J151_RS09685	COG0167	dihydroorotate dehydrogenase activity
J151_RS09700	COG1012	belongs to the aldehyde dehydrogenase family
J151_RS09715	COG1215	transferase activity, transferring glycosyl groups
J151_RS09720	COG0726	polysaccharide deacetylase
J151_RS09720	COG1649	PFAM Uncharacterised BCR, COG1649
J151_RS09735	COG3210	domain, Protein
J151_RS09740	COG3210	domain, Protein
J151_RS09780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J151_RS09785	COG0124	histidyl-tRNA synthetase
J151_RS09795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J151_RS09800	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J151_RS09805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J151_RS09810	COG0131	Imidazoleglycerol-phosphate dehydratase
J151_RS09810	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J151_RS09815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J151_RS09820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J151_RS09825	COG0107	imidazoleglycerol-phosphate synthase activity
J151_RS09830	COG0140	phosphoribosyl-ATP diphosphatase activity
J151_RS09830	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J151_RS09845	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
J151_RS09850	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
J151_RS09855	COG0235	Class ii aldolase
J151_RS09860	COG0531	amino acid
J151_RS09865	COG0531	amino acid
J151_RS09875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J151_RS09880	COG0277	FAD linked oxidase domain protein
J151_RS09900	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J151_RS09945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J151_RS09950	COG2258	MOSC domain
J151_RS09955	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J151_RS09960	COG0505	Belongs to the CarA family
J151_RS09970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J151_RS09975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J151_RS09985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J151_RS10030	COG3279	Response regulator of the LytR AlgR family
J151_RS10035	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
J151_RS10040	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J151_RS10050	COG0784	Response regulator, receiver
J151_RS10050	COG2198	Histidine kinase
J151_RS10050	COG2205	protein histidine kinase activity
J151_RS10055	COG1024	Enoyl-CoA hydratase
J151_RS10060	COG0318	PFAM AMP-dependent synthetase and ligase
J151_RS10095	COG2267	carboxylic ester hydrolase activity
J151_RS10105	COG2201	protein-glutamate methylesterase activity
J151_RS10110	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
J151_RS10120	COG0840	transmembrane signaling receptor activity
J151_RS10125	COG0840	transmembrane signaling receptor activity
J151_RS10130	COG0840	transmembrane signaling receptor activity
J151_RS10140	COG0840	transmembrane signaling receptor activity
J151_RS10145	COG0840	transmembrane signaling receptor activity
J151_RS10150	COG0840	transmembrane signaling receptor activity
J151_RS10155	COG0840	transmembrane signaling receptor activity
J151_RS10170	COG0840	transmembrane signaling receptor activity
J151_RS10190	COG0840	transmembrane signaling receptor activity
J151_RS10195	COG2198	Histidine kinase
J151_RS10195	COG0643	Histidine kinase
J151_RS10200	COG0745	RESPONSE REGULATOR receiver
J151_RS10210	COG0835	chemotaxis
J151_RS10220	COG1360	Flagellar Motor Protein
J151_RS10225	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J151_RS10310	COG0641	radical SAM
J151_RS10325	COG0784	Response regulator, receiver
J151_RS10325	COG2198	Histidine kinase
J151_RS10325	COG0643	Histidine kinase
J151_RS10355	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J151_RS10385	COG1684	flagellar biosynthetic protein fliR
J151_RS10400	COG3190	flagellar
J151_RS10450	COG1677	Flagellar hook-basal body complex protein FliE
J151_RS10480	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS10485	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS10490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J151_RS10510	COG2201	protein-glutamate methylesterase activity
J151_RS10540	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J151_RS10545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J151_RS10550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J151_RS10560	COG3951	Flagellar rod assembly protein muramidase FlgJ
J151_RS10560	COG1705	Flagellar rod assembly protein muramidase FlgJ
J151_RS10565	COG1706	bacterial-type flagellum-dependent cell motility
J151_RS10570	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J151_RS10580	COG4787	bacterial-type flagellum-dependent cell motility
J151_RS10590	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J151_RS10595	COG1558	bacterial-type flagellum-dependent cell motility
J151_RS10605	COG0784	Response regulator, receiver
J151_RS10605	COG0835	chemotaxis
J151_RS10625	COG5002	protein histidine kinase activity
J151_RS10655	COG2915	High frequency lysogenization protein hflD homolog
J151_RS10660	COG0482	sulfurtransferase activity
J151_RS10675	COG0542	response to heat
J151_RS10685	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J151_RS10695	COG0492	ferredoxin-NADP+ reductase activity
J151_RS10700	COG1674	ftsk spoiiie
J151_RS10710	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J151_RS10720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J151_RS10725	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J151_RS10735	COG0183	Belongs to the thiolase family
J151_RS10740	COG1024	Enoyl-CoA hydratase
J151_RS10740	COG1250	3-hydroxyacyl-CoA dehydrogenase
J151_RS10755	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J151_RS10765	COG1426	Protein conserved in bacteria
J151_RS10775	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J151_RS10780	COG1160	GTP binding
J151_RS10785	COG0303	'Molybdopterin
J151_RS10790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J151_RS10825	COG0708	Exodeoxyribonuclease III
J151_RS10835	COG0303	'Molybdopterin
J151_RS10840	COG0746	molybdenum cofactor guanylyltransferase activity
J151_RS10855	COG1914	H( )-stimulated, divalent metal cation uptake system
J151_RS10870	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J151_RS10875	COG0668	transmembrane transport
J151_RS10885	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J151_RS10900	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS10905	COG1183	phosphatidylcholine synthase activity
J151_RS10915	COG3243	poly(R)-hydroxyalkanoic acid synthase
J151_RS10930	COG0723	plastoquinol--plastocyanin reductase activity
J151_RS10930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J151_RS10940	COG2183	response to ionizing radiation
J151_RS10945	COG0784	Response regulator, receiver
J151_RS10945	COG2205	protein histidine kinase activity
J151_RS11010	COG0800	Aldolase
J151_RS11015	COG0129	dihydroxy-acid dehydratase activity
J151_RS11020	COG0363	glucosamine-6-phosphate deaminase activity
J151_RS11025	COG0837	glucose binding
J151_RS11030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J151_RS11050	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J151_RS11065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J151_RS11070	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J151_RS11080	COG4591	ABC-type transport system involved in lipoprotein release permease component
J151_RS11085	COG1136	(ABC) transporter
J151_RS11100	COG0811	peptide transport
J151_RS11110	COG1132	(ABC) transporter
J151_RS11115	COG1663	tetraacyldisaccharide 4'-kinase activity
J151_RS11120	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J151_RS11125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J151_RS11135	COG0322	excinuclease ABC activity
J151_RS11140	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J151_RS11160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J151_RS11165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J151_RS11180	COG2801	Transposase and inactivated derivatives
J151_RS11190	COG0582	viral genome integration into host DNA
J151_RS11200	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J151_RS11220	COG1054	Belongs to the UPF0176 family
J151_RS11230	COG1530	ribonuclease E activity
J151_RS11240	COG3064	Membrane
J151_RS11245	COG0428	transporter
J151_RS11255	COG2154	pterin-4-alpha-carbinolamine dehydratase
J151_RS11260	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J151_RS11260	COG0316	Belongs to the HesB IscA family
J151_RS11315	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS11350	COG1238	metal cluster binding
J151_RS11385	COG3279	Response regulator of the LytR AlgR family
J151_RS11430	COG4566	intracellular signal transduction
J151_RS11440	COG5001	Diguanylate cyclase
J151_RS11455	COG3685	Protein conserved in bacteria
J151_RS11475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J151_RS11475	COG1648	precorrin-2 dehydrogenase activity
J151_RS11490	COG2814	Major facilitator Superfamily
J151_RS11505	COG1335	isochorismatase
J151_RS11520	COG2197	response regulator
J151_RS11540	COG0583	DNA-binding transcription factor activity
J151_RS11545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J151_RS11550	COG3002	Belongs to the UPF0753 family
J151_RS11565	COG1396	sequence-specific DNA binding
J151_RS11570	COG5489	Protein of unknown function (DUF736)
J151_RS11575	COG2003	Belongs to the UPF0758 family
J151_RS11600	COG0582	viral genome integration into host DNA
J151_RS11615	COG4774	siderophore transport
J151_RS11630	COG2336	PFAM SpoVT AbrB
J151_RS11655	COG4206	TonB-dependent receptor
J151_RS11675	COG2273	Hydrolase Family 16
J151_RS11675	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
J151_RS11695	COG2274	protein secretion by the type I secretion system
J151_RS11745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J151_RS11750	COG0270	DNA (cytosine-5-)-methyltransferase activity
J151_RS11800	COG4804	nuclease activity
J151_RS11820	COG5006	permease, DMT superfamily
J151_RS11835	COG2249	NAD(P)H dehydrogenase (quinone) activity
J151_RS11845	COG3938	Belongs to the proline racemase family
J151_RS11860	COG2807	transmembrane transport
J151_RS11865	COG2207	Transcriptional regulator
J151_RS12015	COG0210	DNA helicase
J151_RS12095	COG2084	Dehydrogenase
J151_RS12115	COG2003	Belongs to the UPF0758 family
J151_RS12150	COG0582	viral genome integration into host DNA
J151_RS12155	COG0519	Catalyzes the synthesis of GMP from XMP
J151_RS12155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J151_RS12165	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J151_RS12175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J151_RS12175	COG0475	glutathione-regulated potassium exporter activity
J151_RS12180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J151_RS12190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J151_RS12195	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J151_RS12205	COG0776	regulation of translation
J151_RS12210	COG0539	negative regulation of cytoplasmic translation
J151_RS12215	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J151_RS12230	COG2957	Belongs to the agmatine deiminase family
J151_RS12235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J151_RS12260	COG0395	ABC-type sugar transport system, permease component
J151_RS12265	COG1175	transmembrane transport
J151_RS12295	COG2350	Protein conserved in bacteria
J151_RS12300	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
J151_RS12305	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J151_RS12310	COG1187	pseudouridine synthase activity
J151_RS12330	COG0436	Aminotransferase
J151_RS12335	COG4133	protoheme IX ABC transporter activity
J151_RS12355	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
J151_RS12360	COG1138	Cytochrome C-type biogenesis protein
J151_RS12380	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J151_RS12385	COG1278	Cold shock
J151_RS12390	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J151_RS12395	COG4988	ABC transporter
J151_RS12405	COG1294	oxidase, subunit
J151_RS12430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J151_RS12435	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J151_RS12445	COG0165	Argininosuccinate lyase
J151_RS12450	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J151_RS12460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J151_RS12465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J151_RS12475	COG0137	argininosuccinate synthase activity
J151_RS12480	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J151_RS12490	COG0215	cysteine-tRNA ligase activity
J151_RS12495	COG2166	iron-sulfur cluster assembly
J151_RS12515	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J151_RS12520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J151_RS12545	COG4302	ethanolamine ammonia-lyase activity
J151_RS12575	COG2963	transposase activity
J151_RS12595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J151_RS12600	COG0402	S-adenosylhomocysteine deaminase activity
J151_RS12610	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J151_RS12615	COG1509	lysine 2,3-aminomutase activity
J151_RS12620	COG3300	MHYT domain
J151_RS12620	COG5001	Diguanylate cyclase
J151_RS12635	COG0483	inositol monophosphate 1-phosphatase activity
J151_RS12640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J151_RS12655	COG0488	(ABC) transporter
J151_RS12660	COG0513	Belongs to the DEAD box helicase family
J151_RS12665	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J151_RS12670	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J151_RS12680	COG0625	glutathione transferase activity
J151_RS12690	COG4681	YaeQ
J151_RS12695	COG2081	HI0933 family
J151_RS12705	COG0501	Belongs to the peptidase M48B family
J151_RS12710	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J151_RS12715	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS12735	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J151_RS12740	COG0860	N-Acetylmuramoyl-L-alanine amidase
J151_RS12745	COG0802	atpase or kinase
J151_RS12750	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J151_RS12750	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J151_RS12755	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J151_RS12760	COG1570	exodeoxyribonuclease VII activity
J151_RS12770	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J151_RS12950	COG0835	chemotaxis
J151_RS12955	COG0840	transmembrane signaling receptor activity
J151_RS12960	COG2094	Belongs to the DNA glycosylase MPG family
J151_RS12965	COG1201	RNA secondary structure unwinding
J151_RS12980	COG2969	positive regulation of protein catabolic process
J151_RS12985	COG0625	glutathione transferase activity
J151_RS12990	COG2857	Cytochrome c1
J151_RS12995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J151_RS13000	COG0723	plastoquinol--plastocyanin reductase activity
J151_RS13005	COG0741	lytic transglycosylase activity
J151_RS13020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J151_RS13025	COG1702	phosphate starvation-inducible protein PhoH
J151_RS13035	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J151_RS13045	COG4535	Mg2 and Co2 transporter CorC
J151_RS13060	COG1012	belongs to the aldehyde dehydrogenase family
J151_RS13070	COG1177	transmembrane transport
J151_RS13075	COG1176	ABC-type spermidine putrescine transport system, permease component I
J151_RS13080	COG3842	ATPase activity
J151_RS13100	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J151_RS13115	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J151_RS13120	COG0174	glutamine synthetase
J151_RS13125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J151_RS13135	COG2703	oxygen carrier activity
J151_RS13140	COG0477	Major facilitator Superfamily
J151_RS13150	COG0243	molybdopterin cofactor binding
J151_RS13155	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J151_RS13160	COG2223	nitrite transmembrane transporter activity
J151_RS13165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J151_RS13175	COG2733	membrane
J151_RS13180	COG5002	protein histidine kinase activity
J151_RS13180	COG0784	Response regulator, receiver
J151_RS13180	COG2205	protein histidine kinase activity
J151_RS13190	COG0477	Major facilitator Superfamily
J151_RS13195	COG2902	Dehydrogenase
J151_RS13205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J151_RS13210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J151_RS13215	COG1609	Transcriptional regulator
J151_RS13220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J151_RS13220	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J151_RS13225	COG1105	Belongs to the carbohydrate kinase PfkB family
J151_RS13230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J151_RS13230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J151_RS13275	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J151_RS13285	COG1862	Preprotein translocase
J151_RS13290	COG0343	queuine tRNA-ribosyltransferase activity
J151_RS13295	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J151_RS13335	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J151_RS13340	COG3291	Pkd domain containing protein
J151_RS13350	COG0405	Gamma-glutamyltransferase
J151_RS13355	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J151_RS13370	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J151_RS13375	COG0742	ribosomal rna small subunit methyltransferase
J151_RS13380	COG0326	Molecular chaperone. Has ATPase activity
J151_RS13450	COG0531	amino acid
J151_RS13465	COG0006	proline dipeptidase activity
J151_RS13475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J151_RS13490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J151_RS13495	COG3938	Belongs to the proline racemase family
J151_RS13505	COG0552	protein localization to endoplasmic reticulum
J151_RS13510	COG1194	a g-specific adenine glycosylase
J151_RS13515	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J151_RS13520	COG0784	Response regulator, receiver
J151_RS13520	COG4191	Histidine kinase
J151_RS13535	COG0322	excinuclease ABC activity
J151_RS13550	COG3040	lipid binding
J151_RS13560	COG1960	acyl-CoA dehydrogenase activity
J151_RS13570	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J151_RS13590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J151_RS13595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J151_RS13600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J151_RS13625	COG0438	transferase activity, transferring glycosyl groups
J151_RS13635	COG0438	transferase activity, transferring glycosyl groups
J151_RS13640	COG0438	transferase activity, transferring glycosyl groups
J151_RS13690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J151_RS13690	COG0072	phenylalanine-tRNA ligase activity
J151_RS13695	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J151_RS13710	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J151_RS13715	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J151_RS13740	COG1082	Xylose isomerase domain protein TIM barrel
J151_RS13755	COG0366	Alpha amylase catalytic
J151_RS13760	COG2963	transposase activity
J151_RS13830	COG2948	multi-organism process
J151_RS13850	COG3505	Type IV secretory pathway VirD4
J151_RS13865	COG0556	nucleotide-excision repair
J151_RS13935	COG4695	Portal protein
J151_RS13980	COG3179	chitinase
J151_RS14060	COG3275	phosphorelay sensor kinase activity
J151_RS14065	COG1611	Belongs to the LOG family
J151_RS14075	COG2095	MarC family integral membrane protein
J151_RS14085	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J151_RS14120	COG1185	polyribonucleotide nucleotidyltransferase activity
J151_RS14125	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J151_RS14130	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J151_RS14135	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J151_RS14140	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J151_RS14145	COG0195	Participates in both transcription termination and antitermination
J151_RS14150	COG0779	Required for maturation of 30S ribosomal subunits
J151_RS14160	COG1007	ATP synthesis coupled electron transport
J151_RS14185	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J151_RS14190	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J151_RS14200	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J151_RS14205	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
J151_RS14210	COG0649	NAD binding
J151_RS14215	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J151_RS14220	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J151_RS14225	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J151_RS14240	COG0149	triose-phosphate isomerase activity
J151_RS14245	COG0300	oxidoreductase activity
J151_RS14280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J151_RS14285	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J151_RS14290	COG0159	tryptophan synthase activity
J151_RS14300	COG0133	tryptophan synthase activity
J151_RS14310	COG0135	phosphoribosylanthranilate isomerase activity
J151_RS14315	COG0101	tRNA pseudouridine synthase activity
J151_RS14335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J151_RS14340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J151_RS14345	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J151_RS14350	COG2890	protein-(glutamine-N5) methyltransferase activity
J151_RS14360	COG0688	phosphatidylethanolamine metabolic process
J151_RS14370	COG0433	COG0433 Predicted ATPase
J151_RS14375	COG0494	nUDIX hydrolase
J151_RS14390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J151_RS14395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J151_RS14420	COG0717	Belongs to the dCTP deaminase family
J151_RS14425	COG0489	protein tyrosine kinase activity
J151_RS14445	COG3590	peptidase
J151_RS14450	COG3590	peptidase
J151_RS14470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J151_RS14475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J151_RS14480	COG2311	Membrane
J151_RS14485	COG1047	Peptidyl-prolyl cis-trans
J151_RS14490	COG0791	NLP P60 protein
J151_RS14495	COG0791	NLP P60 protein
J151_RS14505	COG4106	trans-aconitate 2-methyltransferase activity
J151_RS14510	COG1301	dicarboxylic acid transport
J151_RS14515	COG1785	Belongs to the alkaline phosphatase family
J151_RS14520	COG0037	tRNA processing
J151_RS14525	COG1722	exodeoxyribonuclease VII activity
J151_RS14530	COG0142	geranyltranstransferase activity
J151_RS14535	COG4104	PAAR repeat-containing protein
J151_RS14545	COG0312	modulator of DNA gyrase
J151_RS14550	COG3028	Belongs to the UPF0307 family
J151_RS14555	COG0312	modulator of DNA gyrase
J151_RS14565	COG3164	Protein of unknown function
J151_RS14575	COG0424	maF-like protein
J151_RS14580	COG2968	Membrane
J151_RS14595	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J151_RS14610	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J151_RS14625	COG0495	leucyl-tRNA aminoacylation
J151_RS14635	COG3118	belongs to the thioredoxin family
J151_RS14660	COG2155	Conserved Protein
J151_RS14705	COG1132	(ABC) transporter
J151_RS14730	COG1538	Outer membrane efflux protein
J151_RS14735	COG0745	RESPONSE REGULATOR receiver
J151_RS14740	COG5002	protein histidine kinase activity
J151_RS14740	COG5000	phosphorelay sensor kinase activity
J151_RS14745	COG0475	glutathione-regulated potassium exporter activity
J151_RS14755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J151_RS14780	COG1187	pseudouridine synthase activity
J151_RS14785	COG5002	protein histidine kinase activity
J151_RS14785	COG5001	Diguanylate cyclase
J151_RS14900	COG0667	Aldo Keto reductase
J151_RS14905	COG2814	Major facilitator Superfamily
J151_RS14910	COG0583	DNA-binding transcription factor activity
J151_RS14920	COG2207	Transcriptional regulator
J151_RS14930	COG1309	transcriptional regulator
J151_RS14955	COG0735	belongs to the Fur family
J151_RS14960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J151_RS14985	COG4452	Inner membrane protein CreD
J151_RS14995	COG2205	protein histidine kinase activity
J151_RS15000	COG0745	RESPONSE REGULATOR receiver
J151_RS15005	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J151_RS15015	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J151_RS15050	COG2198	Histidine kinase
J151_RS15050	COG0643	Histidine kinase
J151_RS15055	COG0840	transmembrane signaling receptor activity
J151_RS15060	COG0835	chemotaxis
J151_RS15065	COG2199	diguanylate cyclase activity
J151_RS15065	COG2202	Pas domain
J151_RS15065	COG2200	EAL domain
J151_RS15070	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J151_RS15075	COG2201	protein-glutamate methylesterase activity
J151_RS15080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J151_RS15085	COG3590	peptidase
J151_RS15095	COG0588	phosphoglycerate mutase activity
J151_RS15100	COG1515	deoxyribonuclease V activity
J151_RS15110	COG1741	Belongs to the pirin family
J151_RS15125	COG1741	Belongs to the pirin family
J151_RS15130	COG1966	Carbon starvation protein
J151_RS15135	COG2879	small protein
J151_RS15190	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J151_RS15195	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
J151_RS15200	COG2080	2 iron, 2 sulfur cluster binding
J151_RS15210	COG2203	Gaf domain
J151_RS15210	COG3706	GGDEF domain
J151_RS15210	COG4251	negative regulation of phosphorylation
J151_RS15210	COG5001	Diguanylate cyclase
J151_RS15250	COG0629	single-stranded DNA binding
J151_RS15255	COG0142	geranyltranstransferase activity
J151_RS15265	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J151_RS15280	COG0527	aspartate kinase activity
J151_RS15285	COG0384	phenazine biosynthesis protein PhzF
J151_RS15290	COG0384	phenazine biosynthesis protein PhzF
J151_RS15300	COG1764	response to oxidative stress
J151_RS15305	COG0540	Belongs to the ATCase OTCase family
J151_RS15310	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J151_RS15315	COG1678	Uncharacterized ACR, COG1678
J151_RS15325	COG0519	Catalyzes the synthesis of GMP from XMP
J151_RS15340	COG5297	Belongs to the glycosyl hydrolase family 6
J151_RS15355	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J151_RS15370	COG0739	heme binding
J151_RS15390	COG0693	protein deglycase activity
J151_RS15400	COG1959	2 iron, 2 sulfur cluster binding
J151_RS15405	COG0719	Fe-S assembly protein
J151_RS15410	COG0396	ATPase activity
J151_RS15415	COG0719	Fe-S assembly protein
J151_RS15420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J151_RS15430	COG2146	nitrite reductase [NAD(P)H] activity
J151_RS15435	COG4774	siderophore transport
J151_RS15440	COG3128	pkhd-type hydroxylase
J151_RS15465	COG1477	protein flavinylation
J151_RS15470	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J151_RS15485	COG1555	photosystem II stabilization
J151_RS15490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J151_RS15500	COG3178	'Phosphotransferase
J151_RS15505	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J151_RS15515	COG0628	permease
J151_RS15525	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J151_RS15535	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J151_RS15555	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J151_RS15560	COG0271	Belongs to the BolA IbaG family
J151_RS15570	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J151_RS15580	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J151_RS15585	COG1137	ATPase activity
J151_RS15600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J151_RS15605	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J151_RS15610	COG1660	Displays ATPase and GTPase activities
J151_RS15620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J151_RS15625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J151_RS15630	COG2239	Acts as a magnesium transporter
J151_RS15640	COG1294	oxidase, subunit
J151_RS15645	COG1271	oxidase subunit
J151_RS15655	COG1113	amino acid transport
J151_RS15675	COG2197	response regulator
J151_RS15680	COG0531	amino acid
J151_RS15700	COG1234	tRNA 3'-trailer cleavage
J151_RS15735	COG2814	Major facilitator Superfamily
J151_RS15745	COG0754	glutathionylspermidine amidase activity
J151_RS15770	COG1842	Phage shock protein A
J151_RS15780	COG0259	pyridoxamine-phosphate oxidase activity
J151_RS15785	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J151_RS15790	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J151_RS15800	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J151_RS15875	COG2814	Major facilitator Superfamily
J151_RS15895	COG2198	Histidine kinase
J151_RS15895	COG2205	protein histidine kinase activity
J151_RS15895	COG0784	Response regulator, receiver
J151_RS15900	COG2353	YceI-like domain
J151_RS15920	COG1760	l-serine dehydratase
J151_RS15930	COG0527	aspartate kinase activity
J151_RS15930	COG0460	homoserine dehydrogenase
J151_RS15935	COG0626	cystathionine gamma-synthase activity
J151_RS15940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J151_RS15945	COG0739	heme binding
J151_RS15950	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J151_RS15955	COG1272	protein, Hemolysin III
J151_RS15960	COG2982	Protein involved in outer membrane biogenesis
J151_RS15965	COG0516	GMP reductase activity
J151_RS15965	COG0517	IMP dehydrogenase activity
J151_RS15970	COG0463	Glycosyl transferase, family 2
J151_RS15975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J151_RS15980	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J151_RS15990	COG4771	TonB-dependent receptor
J151_RS16000	COG1309	transcriptional regulator
J151_RS16010	COG1960	acyl-CoA dehydrogenase activity
J151_RS16035	COG0509	glycine decarboxylation via glycine cleavage system
J151_RS16040	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J151_RS16050	COG0330	HflC and HflK could
J151_RS16055	COG1742	UPF0060 membrane protein
J151_RS16060	COG3956	TIGRFAM MazG family protein
J151_RS16070	COG0494	nUDIX hydrolase
J151_RS16080	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J151_RS16085	COG0837	glucose binding
J151_RS16100	COG3858	chitin binding
J151_RS16100	COG1388	LysM domain
J151_RS16105	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J151_RS16115	COG1472	Belongs to the glycosyl hydrolase 3 family
J151_RS16130	COG0531	amino acid
J151_RS16140	COG1486	melibiose metabolic process
J151_RS16150	COG3537	Alpha-1,2-mannosidase
J151_RS16185	COG3142	Participates in the control of copper homeostasis
J151_RS16190	COG1446	asparaginase
J151_RS16220	COG0643	Histidine kinase
J151_RS16220	COG0784	Response regulator, receiver
J151_RS16220	COG2198	Histidine kinase
J151_RS16225	COG0840	transmembrane signaling receptor activity
J151_RS16230	COG0835	chemotaxis
J151_RS16245	COG0189	ligase activity
J151_RS16255	COG1397	ADP-ribosylglycohydrolase
J151_RS16265	COG1199	ATP-dependent helicase activity
J151_RS16275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J151_RS16280	COG1215	transferase activity, transferring glycosyl groups
J151_RS16290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J151_RS16295	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J151_RS16300	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
J151_RS16305	COG0535	radical SAM domain protein
J151_RS16310	COG0535	radical SAM domain protein
J151_RS16325	COG0837	glucose binding
J151_RS16335	COG1643	Atp-dependent helicase
J151_RS16340	COG0783	Belongs to the Dps family
J151_RS16345	COG0514	ATP-dependent DNA helicase (RecQ)
J151_RS16380	COG0840	transmembrane signaling receptor activity
J151_RS16400	COG3920	Histidine kinase
J151_RS16405	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J151_RS16415	COG0602	queuosine metabolic process
J151_RS16425	COG2885	chlorophyll binding
J151_RS16430	COG0823	Involved in the tonB-independent uptake of proteins
J151_RS16440	COG0848	biopolymer transport protein
J151_RS16450	COG0824	Thioesterase
J151_RS16455	COG2255	four-way junction helicase activity
J151_RS16465	COG3158	transport of potassium into the cell
J151_RS16470	COG0632	four-way junction helicase activity
J151_RS16475	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J151_RS16480	COG0217	transcriptional regulatory protein
J151_RS16495	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J151_RS16510	COG0477	Major facilitator Superfamily
J151_RS16545	COG0488	(ABC) transporter
J151_RS16580	COG4651	solute:proton antiporter activity
J151_RS16580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J151_RS16605	COG4772	TonB-dependent receptor
J151_RS16615	COG4264	IucA IucC family
J151_RS16630	COG0019	diaminopimelate decarboxylase activity
J151_RS16655	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J151_RS16665	COG1492	cobalamin metabolic process
J151_RS16675	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
J151_RS16695	COG4206	TonB-dependent receptor
J151_RS16700	COG0542	response to heat
J151_RS16705	COG1116	anion transmembrane transporter activity
J151_RS16710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J151_RS16715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J151_RS16720	COG0667	Aldo Keto reductase
J151_RS16725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J151_RS16730	COG4771	TonB-dependent receptor
J151_RS16735	COG2827	Endonuclease containing a URI domain
J151_RS16775	COG1877	trehalose-phosphatase activity
J151_RS16780	COG3387	PFAM Glycoside hydrolase 15-related
J151_RS16795	COG0840	transmembrane signaling receptor activity
J151_RS16800	COG3011	Protein conserved in bacteria
J151_RS16815	COG0564	pseudouridine synthase activity
J151_RS16820	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J151_RS16830	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J151_RS16830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J151_RS16860	COG2951	lytic endotransglycosylase activity
J151_RS16865	COG4644	lycopene metabolic process
J151_RS16885	COG2369	cell adhesion
J151_RS16910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J151_RS16915	COG0045	succinate-CoA ligase (ADP-forming) activity
J151_RS16930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J151_RS16960	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
J151_RS16965	COG0237	dephospho-CoA kinase activity
J151_RS16985	COG2801	Transposase and inactivated derivatives
J151_RS16990	COG5002	protein histidine kinase activity
J151_RS16995	COG0745	RESPONSE REGULATOR receiver
J151_RS17005	COG0189	ligase activity
J151_RS17065	COG2003	Belongs to the UPF0758 family
J151_RS17090	COG0784	Response regulator, receiver
J151_RS17090	COG4191	Histidine kinase
J151_RS17095	COG4191	Histidine kinase
J151_RS17095	COG0784	Response regulator, receiver
J151_RS17205	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J151_RS17230	COG2022	thiamine diphosphate biosynthetic process
J151_RS17235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J151_RS17240	COG3273	potassium ion transport
J151_RS17240	COG0471	metal ion transport
J151_RS17260	COG1970	mechanosensitive ion channel activity
J151_RS17285	COG3250	beta-galactosidase activity
J151_RS17290	COG4948	Mandelate Racemase Muconate Lactonizing
J151_RS17305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J151_RS17315	COG0308	aminopeptidase N
J151_RS17365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J151_RS17375	COG2895	sulfate adenylyltransferase (ATP) activity
J151_RS17375	COG0529	Catalyzes the synthesis of activated sulfate
J151_RS17380	COG0175	sulfate reduction
J151_RS17385	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J151_RS17390	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J151_RS17395	COG0175	sulfate reduction
J151_RS17415	COG2198	Histidine kinase
J151_RS17415	COG0784	Response regulator, receiver
J151_RS17415	COG2205	protein histidine kinase activity
J151_RS17450	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
J151_RS17455	COG3588	fructose-bisphosphate aldolase
J151_RS17460	COG0469	pyruvate kinase activity
J151_RS17470	COG0126	phosphoglycerate kinase activity
J151_RS17490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J151_RS17500	COG3047	cAMP biosynthetic process
J151_RS17505	COG3047	cAMP biosynthetic process
J151_RS17515	COG3453	Protein conserved in bacteria
J151_RS17515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J151_RS17520	COG0725	ABC transporter, periplasmic molybdate-binding protein
J151_RS17525	COG4149	molybdate abc transporter
J151_RS17530	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J151_RS17565	COG1376	ErfK ybiS ycfS ynhG family protein
J151_RS17570	COG0739	heme binding
J151_RS17580	COG4773	Receptor
J151_RS17595	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J151_RS17600	COG1301	dicarboxylic acid transport
J151_RS17610	COG2304	oxidoreductase activity
J151_RS17630	COG0714	Associated with various cellular activities
J151_RS17660	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J151_RS17685	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J151_RS17695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J151_RS17705	COG0194	GDP metabolic process
J151_RS17710	COG1561	YicC-like family, N-terminal region
J151_RS17715	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J151_RS17725	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J151_RS17730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J151_RS17745	COG0006	proline dipeptidase activity
J151_RS17755	COG0006	proline dipeptidase activity
J151_RS17760	COG3079	Belongs to the UPF0149 family
J151_RS17775	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J151_RS17785	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J151_RS17795	COG2912	Transglutaminase-like superfamily
J151_RS17800	COG1773	rubredoxin
J151_RS17805	COG0352	thiamine-phosphate diphosphorylase activity
J151_RS17820	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J151_RS17835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J151_RS17865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J151_RS17870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J151_RS17875	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS17885	COG0671	phosphoesterase, PA-phosphatase related
J151_RS17890	COG3781	membrane
J151_RS17900	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J151_RS17905	COG0563	adenylate kinase activity
J151_RS17920	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
J151_RS17930	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J151_RS17955	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J151_RS17965	COG0840	transmembrane signaling receptor activity
J151_RS17970	COG0405	Gamma-glutamyltransferase
J151_RS17975	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J151_RS17995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J151_RS18000	COG0473	3-isopropylmalate dehydrogenase activity
J151_RS18005	COG0066	3-isopropylmalate dehydratase activity
J151_RS18010	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J151_RS18030	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J151_RS18035	COG1538	Outer membrane efflux protein
J151_RS18040	COG1519	Transferase
J151_RS18045	COG1560	Kdo2-lipid A biosynthetic process
J151_RS18070	COG0281	malic enzyme
J151_RS18070	COG0280	phosphate acetyltransferase
J151_RS18075	COG1301	dicarboxylic acid transport
J151_RS18100	COG0583	DNA-binding transcription factor activity
J151_RS18105	COG0667	Aldo Keto reductase
J151_RS18120	COG2197	response regulator
J151_RS18130	COG0642	Histidine kinase
J151_RS18145	COG2851	Citrate transporter
J151_RS18150	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS18155	COG1609	Transcriptional regulator
J151_RS18160	COG2211	Major facilitator Superfamily
J151_RS18185	COG1162	GTPase activity
J151_RS18205	COG4773	Receptor
J151_RS18210	COG0726	polysaccharide deacetylase
J151_RS18215	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J151_RS18230	COG2963	transposase activity
J151_RS18235	COG2801	Transposase and inactivated derivatives
J151_RS18250	COG1307	EDD domain protein, DegV family
J151_RS18255	COG0242	peptide deformylase activity
J151_RS18275	COG0457	Tetratricopeptide repeat
J151_RS18280	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
J151_RS18285	COG1215	transferase activity, transferring glycosyl groups
J151_RS18290	COG1215	transferase activity, transferring glycosyl groups
J151_RS18305	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J151_RS18360	COG2188	Transcriptional regulator
J151_RS18370	COG1450	Type ii and iii secretion system protein
J151_RS18385	COG3166	PFAM Fimbrial assembly family protein
J151_RS18390	COG3156	type II secretion system protein K
J151_RS18395	COG4795	General secretion pathway protein
J151_RS18400	COG2165	general secretion pathway protein
J151_RS18405	COG4970	Tfp pilus assembly protein FimT
J151_RS18410	COG2165	general secretion pathway protein
J151_RS18415	COG1459	type II secretion system
J151_RS18420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J151_RS18425	COG1404	Belongs to the peptidase S8 family
J151_RS18430	COG5295	Hep Hag repeat protein
J151_RS18435	COG1404	Belongs to the peptidase S8 family
J151_RS18440	COG5295	Hep Hag repeat protein
J151_RS18450	COG0047	phosphoribosylformylglycinamidine synthase activity
J151_RS18450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J151_RS18455	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J151_RS18460	COG4974	Belongs to the 'phage' integrase family
J151_RS18475	COG0795	lipopolysaccharide-transporting ATPase activity
J151_RS18485	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J151_RS18500	COG0525	valine-tRNA ligase activity
J151_RS18530	COG1183	phosphatidylcholine synthase activity
J151_RS18540	COG0442	prolyl-tRNA aminoacylation
J151_RS18555	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J151_RS18560	COG1127	ABC transporter
J151_RS18565	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J151_RS18565	COG3218	ABC-type transport auxiliary lipoprotein component
J151_RS18600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J151_RS18605	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
J151_RS18605	COG0662	Cupin 2, conserved barrel domain protein
J151_RS18635	COG2086	electron transfer activity
J151_RS18650	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J151_RS18650	COG0546	phosphoglycolate phosphatase activity
J151_RS18655	COG0277	FAD linked oxidase domain protein
J151_RS18670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J151_RS18700	COG0438	transferase activity, transferring glycosyl groups
J151_RS18700	COG1216	Glycosyl transferase, family 2
J151_RS18720	COG0626	cystathionine gamma-synthase activity
J151_RS18755	COG0625	glutathione transferase activity
J151_RS18765	COG0513	Belongs to the DEAD box helicase family
J151_RS18775	COG4206	TonB-dependent receptor
J151_RS18780	COG0720	synthase
J151_RS18790	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J151_RS18800	COG1956	GAF domain-containing protein
J151_RS18810	COG2819	hydrolase of the alpha beta superfamily
J151_RS18825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J151_RS18830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J151_RS18845	COG0339	signal peptide processing
J151_RS18895	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J151_RS18900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J151_RS18905	COG4591	ABC-type transport system involved in lipoprotein release permease component
J151_RS18905	COG1136	(ABC) transporter
J151_RS18910	COG0577	efflux transmembrane transporter activity
J151_RS18910	COG1136	(ABC) transporter
J151_RS18915	COG0577	efflux transmembrane transporter activity
J151_RS18930	COG4191	Histidine kinase
J151_RS18935	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J151_RS18950	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J151_RS18955	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J151_RS18960	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J151_RS18965	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J151_RS18970	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J151_RS18975	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J151_RS18985	COG0356	it plays a direct role in the translocation of protons across the membrane
J151_RS19005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J151_RS19015	COG0508	dehydrogenase complex catalyzes the overall conversion of
J151_RS19060	COG2011	ABC-type metal ion transport system permease component
J151_RS19065	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J151_RS19070	COG0697	spore germination
J151_RS19075	COG1666	GTP binding
J151_RS19085	COG5002	protein histidine kinase activity
J151_RS19085	COG2198	Histidine kinase
J151_RS19085	COG0784	Response regulator, receiver
J151_RS19110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J151_RS19115	COG1187	pseudouridine synthase activity
J151_RS19120	COG2813	Specifically methylates the guanine in position
J151_RS19140	COG2202	Pas domain
J151_RS19140	COG2205	protein histidine kinase activity
J151_RS19160	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J151_RS19165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J151_RS19220	COG0842	Transport permease protein
J151_RS19225	COG1131	(ABC) transporter
J151_RS19230	COG0025	NhaP-type Na H and K H
J151_RS19235	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
J151_RS19240	COG1573	uracil-dna glycosylase
J151_RS19250	COG3384	dioxygenase
J151_RS19260	COG0583	DNA-binding transcription factor activity
J151_RS19270	COG0667	Aldo Keto reductase
J151_RS19280	COG3590	peptidase
J151_RS19300	COG0531	amino acid
J151_RS19315	COG2972	Histidine kinase
J151_RS19330	COG3685	Protein conserved in bacteria
J151_RS19335	COG3546	catalase activity
J151_RS19380	COG1271	oxidase subunit
J151_RS19385	COG1294	oxidase, subunit
J151_RS19400	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS19405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J151_RS19425	COG1132	(ABC) transporter
J151_RS19440	COG1063	alcohol dehydrogenase
J151_RS19515	COG0251	oxidation-reduction process
J151_RS19545	COG0840	transmembrane signaling receptor activity
J151_RS19565	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J151_RS19605	COG0024	Methionine aminopeptidase
J151_RS19625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J151_RS19630	COG1490	D-aminoacyl-tRNA deacylase activity
J151_RS19635	COG1560	Kdo2-lipid A biosynthetic process
J151_RS19685	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J151_RS19685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J151_RS19690	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J151_RS19695	COG0242	peptide deformylase activity
J151_RS19700	COG1652	LysM domain
J151_RS19705	COG0758	DNA mediated transformation
J151_RS19710	COG2922	Belongs to the Smg family
J151_RS19725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J151_RS19725	COG1754	DNA topoisomerase type I activity
J151_RS19730	COG0009	L-threonylcarbamoyladenylate synthase
J151_RS19745	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS19755	COG0616	signal peptide processing
J151_RS19760	COG0534	Mate efflux family protein
J151_RS19780	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J151_RS19785	COG0625	glutathione transferase activity
J151_RS19800	COG1252	NADH dehydrogenase
J151_RS19805	COG2860	membrane
J151_RS19810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J151_RS19815	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J151_RS19820	COG2201	protein-glutamate methylesterase activity
J151_RS19825	COG2177	Part of the ABC transporter FtsEX involved in
J151_RS19830	COG2884	Cell division ATP-binding protein ftsE
J151_RS19835	COG0513	Belongs to the DEAD box helicase family
J151_RS19840	COG3118	belongs to the thioredoxin family
J151_RS19845	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J151_RS19850	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
J151_RS19855	COG0583	DNA-binding transcription factor activity
J151_RS19900	COG1518	maintenance of DNA repeat elements
J151_RS19905	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
J151_RS19915	COG1652	LysM domain
J151_RS19920	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J151_RS19920	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J151_RS19925	COG1473	amidohydrolase
J151_RS19930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J151_RS19935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J151_RS19945	COG5383	Protein conserved in bacteria
J151_RS19985	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
J151_RS19990	COG3023	N-Acetylmuramoyl-L-alanine amidase
J151_RS20000	COG4948	Mandelate Racemase Muconate Lactonizing
J151_RS20010	COG0531	amino acid
J151_RS20025	COG4682	membrane
J151_RS20030	COG2133	pyrroloquinoline quinone binding
J151_RS20040	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J151_RS20045	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J151_RS20055	COG1610	YqeY-like protein
J151_RS20060	COG1295	ribonuclease BN
J151_RS20065	COG0358	DNA primase activity
J151_RS20080	COG0109	protoheme IX farnesyltransferase activity
J151_RS20110	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
J151_RS20125	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J151_RS20165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J151_RS20170	COG0739	heme binding
J151_RS20175	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J151_RS20185	COG2223	nitrite transmembrane transporter activity
J151_RS20190	COG0708	Exodeoxyribonuclease III
J151_RS20195	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J151_RS20205	COG1192	Involved in chromosome partitioning
J151_RS20210	COG1475	DNA binding
J151_RS20225	COG0463	Glycosyl transferase, family 2
J151_RS20245	COG0756	dUTP diphosphatase activity
J151_RS20250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J151_RS20255	COG2003	Belongs to the UPF0758 family
J151_RS20260	COG0018	arginyl-trna synthetase
J151_RS20275	COG4221	oxidoreductase activity
J151_RS20280	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J151_RS20280	COG2755	lipolytic protein G-D-S-L family
J151_RS20290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J151_RS20300	COG1166	arginine decarboxylase activity
J151_RS20305	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J151_RS20345	COG0606	chelatase, subunit chli
J151_RS20440	COG0606	chelatase, subunit chli
J151_RS20455	COG4943	cyclic-guanylate-specific phosphodiesterase activity
J151_RS20490	COG1690	Belongs to the RtcB family
J151_RS20530	COG1090	epimerase
J151_RS20540	COG0642	Histidine kinase
J151_RS20560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J151_RS20585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J151_RS20590	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J151_RS20605	COG0753	catalase activity
J151_RS20620	COG2197	response regulator
J151_RS20625	COG4585	Histidine kinase
J151_RS20630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J151_RS20635	COG1136	(ABC) transporter
J151_RS20660	COG0697	spore germination
J151_RS20675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J151_RS20680	COG0180	Tryptophanyl-tRNA synthetase
J151_RS20685	COG3237	CsbD-like
J151_RS20725	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J151_RS20740	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J151_RS20785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J151_RS20810	COG1199	ATP-dependent helicase activity
J151_RS20825	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J151_RS20885	COG0625	glutathione transferase activity
J151_RS20925	COG4555	ABC transporter
J151_RS20935	COG1476	TRANSCRIPTIONal
J151_RS20980	COG0543	2 iron, 2 sulfur cluster binding
J151_RS20980	COG0633	Ferredoxin
J151_RS20985	COG1131	(ABC) transporter
J151_RS20990	COG0842	Transport permease protein
J151_RS21000	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J151_RS21030	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J151_RS21035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J151_RS21045	COG1042	CoA-binding domain protein
J151_RS21045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J151_RS21045	COG0045	succinate-CoA ligase (ADP-forming) activity
J151_RS21050	COG2239	Acts as a magnesium transporter
J151_RS21055	COG3338	carbonate dehydratase activity
J151_RS21065	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J151_RS21070	COG3387	PFAM Glycoside hydrolase 15-related
J151_RS21085	COG3100	YcgL domain-containing protein
J151_RS21090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J151_RS21100	COG0463	Glycosyl transferase, family 2
J151_RS21115	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS21155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J151_RS21170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J151_RS21195	COG4946	Tricorn protease homolog
J151_RS21195	COG0823	Involved in the tonB-independent uptake of proteins
J151_RS21195	COG1506	peptidase
J151_RS21210	COG0408	coproporphyrinogen oxidase activity
J151_RS21245	COG0515	serine threonine protein kinase
J151_RS21245	COG2815	serine threonine protein kinase
J151_RS21250	COG0631	protein serine/threonine phosphatase activity
J151_RS21410	COG0210	DNA helicase
J151_RS21425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J151_RS21430	COG0583	DNA-binding transcription factor activity
J151_RS21435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J151_RS21445	COG2159	amidohydrolase
J151_RS21465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J151_RS21485	COG0357	Ribosomal RNA small subunit methyltransferase G
J151_RS21490	COG3540	Alkaline phosphatase
J151_RS21500	COG2091	lysine biosynthetic process via aminoadipic acid
J151_RS21520	COG0708	Exodeoxyribonuclease III
J151_RS21525	COG1940	carbohydrate kinase activity
J151_RS21525	COG1846	Transcriptional regulator
J151_RS21535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J151_RS21545	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J151_RS21550	COG3162	membrane
J151_RS21560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J151_RS21590	COG3507	Belongs to the glycosyl hydrolase 43 family
J151_RS21610	COG1028	Short-chain dehydrogenase reductase Sdr
J151_RS21615	COG0179	Fumarylacetoacetate (FAA) hydrolase
J151_RS21620	COG4948	Mandelate Racemase Muconate Lactonizing
J151_RS21630	COG3254	rhamnose metabolic process
J151_RS21635	COG0738	Major facilitator superfamily
J151_RS21640	COG1414	Transcriptional regulator
J151_RS21645	COG1971	Probably functions as a manganese efflux pump
J151_RS21650	COG2205	protein histidine kinase activity
J151_RS21665	COG3459	Glycosyltransferase 36 associated
J151_RS21670	COG2211	Major facilitator Superfamily
J151_RS21675	COG3265	gluconokinase activity
J151_RS21680	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J151_RS21700	COG2911	Protein conserved in bacteria
J151_RS21705	COG0729	surface antigen
J151_RS21745	COG0752	glycyl-tRNA synthetase alpha subunit
J151_RS21750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J151_RS21760	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J151_RS21760	COG0519	Catalyzes the synthesis of GMP from XMP
J151_RS21770	COG0805	protein transport
J151_RS21775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J151_RS21780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J151_RS21790	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J151_RS21810	COG2974	May be involved in recombination
J151_RS21815	COG0037	tRNA processing
J151_RS21820	COG2115	Belongs to the xylose isomerase family
J151_RS21830	COG3661	Belongs to the glycosyl hydrolase 67 family
J151_RS21840	COG4948	Mandelate Racemase Muconate Lactonizing
J151_RS21850	COG1472	Belongs to the glycosyl hydrolase 3 family
J151_RS21855	COG0246	Mannitol dehydrogenase
J151_RS21935	COG3386	PFAM SMP-30 Gluconolaconase
J151_RS21945	COG3250	beta-galactosidase activity
J151_RS21950	COG1904	glucuronate isomerase
J151_RS21955	COG3693	PFAM glycoside hydrolase, family 10
J151_RS21970	COG3693	PFAM glycoside hydrolase, family 10
J151_RS21985	COG2211	Major facilitator Superfamily
J151_RS22030	COG2937	Belongs to the GPAT DAPAT family
J151_RS22065	COG0284	orotidine-5'-phosphate decarboxylase activity
J151_RS22070	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
J151_RS22075	COG3132	Protein of unknown function, DUF480
J151_RS22090	COG0210	DNA helicase
J151_RS22095	COG1435	thymidine kinase activity
J151_RS22105	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
J151_RS22115	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J151_RS22145	COG3135	benzoate transporter
J151_RS22165	COG0676	glucose-6-phosphate 1-epimerase activity
J151_RS22175	COG3012	SEC-C Motif Domain Protein
J151_RS22180	COG0730	response to heat
J151_RS22200	COG0302	gtp cyclohydrolase
J151_RS22215	COG1566	PFAM secretion protein HlyD family protein
J151_RS22225	COG1289	transmembrane transporter activity
J151_RS22230	COG0477	Major facilitator Superfamily
J151_RS22240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J151_RS22260	COG4691	Plasmid stability protein
J151_RS22265	COG1487	ribonuclease activity
J151_RS22290	COG0564	pseudouridine synthase activity
J151_RS22325	COG0439	Biotin carboxylase
J151_RS22365	COG1074	ATP-dependent DNA helicase activity
J151_RS22370	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J151_RS22385	COG1127	ABC transporter
J151_RS22390	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J151_RS22395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J151_RS22410	COG2853	Lipoprotein
J151_RS22420	COG0386	Belongs to the glutathione peroxidase family
J151_RS22430	COG1322	Protein conserved in bacteria
J151_RS22435	COG0604	alcohol dehydrogenase
J151_RS22455	COG0625	glutathione transferase activity
J151_RS22465	COG0531	amino acid
J151_RS22470	COG3537	Alpha-1,2-mannosidase
J151_RS22480	COG3706	GGDEF domain
J151_RS22485	COG3835	regulator
J151_RS22490	COG1929	Belongs to the glycerate kinase type-1 family
J151_RS22495	COG2271	Major facilitator Superfamily
J151_RS22510	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J151_RS22515	COG0861	Integral membrane protein TerC family
J151_RS22525	COG0584	glycerophosphoryl diester phosphodiesterase
J151_RS22540	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J151_RS22545	COG0726	polysaccharide deacetylase
J151_RS22550	COG0706	membrane insertase activity
J151_RS22555	COG0594	ribonuclease P activity