locus-tag	class	description
AB890_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AB890_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AB890_RS00020	COG0187	DNA topoisomerase II activity
AB890_RS00030	COG0501	Belongs to the peptidase M48B family
AB890_RS00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AB890_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB890_RS00115	COG0793	Belongs to the peptidase S41A family
AB890_RS00120	COG4942	peptidase
AB890_RS00130	COG2234	aminopeptidase activity
AB890_RS00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AB890_RS00150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AB890_RS00155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AB890_RS00160	COG1064	alcohol dehydrogenase
AB890_RS00165	COG0493	'glutamate synthase
AB890_RS00170	COG0070	glutamate synthase
AB890_RS00170	COG0069	glutamate synthase activity
AB890_RS00170	COG0067	glutamate synthase
AB890_RS00215	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AB890_RS00230	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AB890_RS00235	COG0297	glycogen (starch) synthase activity
AB890_RS00235	COG0438	transferase activity, transferring glycosyl groups
AB890_RS00255	COG0367	asparagine synthase
AB890_RS00285	COG1132	(ABC) transporter
AB890_RS00315	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AB890_RS00400	COG1111	helicase
AB890_RS00400	COG1205	dead DEAH box helicase
AB890_RS00405	COG1272	protein, Hemolysin III
AB890_RS00425	COG0300	oxidoreductase activity
AB890_RS00430	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS00450	COG2249	NAD(P)H dehydrogenase (quinone) activity
AB890_RS00500	COG3237	CsbD-like
AB890_RS00550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB890_RS00560	COG0477	Major facilitator Superfamily
AB890_RS00600	COG0714	Associated with various cellular activities
AB890_RS00630	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AB890_RS00640	COG4772	TonB-dependent receptor
AB890_RS00650	COG0662	Cupin 2, conserved barrel domain protein
AB890_RS00655	COG1012	belongs to the aldehyde dehydrogenase family
AB890_RS00680	COG1304	FMN binding
AB890_RS00695	COG4585	Histidine kinase
AB890_RS00700	COG2197	response regulator
AB890_RS00720	COG3710	Transcriptional regulator
AB890_RS00725	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AB890_RS00800	COG0366	Alpha amylase catalytic
AB890_RS00805	COG0366	Alpha amylase catalytic
AB890_RS00810	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AB890_RS00830	COG2755	lipolytic protein G-D-S-L family
AB890_RS00830	COG0657	acetylesterase activity
AB890_RS00840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AB890_RS00855	COG3507	Belongs to the glycosyl hydrolase 43 family
AB890_RS00860	COG1609	Transcriptional regulator
AB890_RS00865	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AB890_RS00870	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS00880	COG2755	lipolytic protein G-D-S-L family
AB890_RS00895	COG3186	Phenylalanine-4-hydroxylase
AB890_RS00900	COG1522	sequence-specific DNA binding
AB890_RS00910	COG1752	Esterase of the alpha-beta hydrolase superfamily
AB890_RS00920	COG1119	ATPase activity
AB890_RS00935	COG1125	glycine betaine transport
AB890_RS00950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AB890_RS00970	COG1396	sequence-specific DNA binding
AB890_RS00995	COG0489	protein tyrosine kinase activity
AB890_RS01000	COG2062	phosphohistidine phosphatase, SixA
AB890_RS01010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB890_RS01055	COG1968	undecaprenyl-diphosphatase activity
AB890_RS01060	COG0174	glutamine synthetase
AB890_RS01065	COG0347	Belongs to the P(II) protein family
AB890_RS01070	COG0004	ammonium transporteR
AB890_RS01075	COG3852	Histidine kinase
AB890_RS01080	COG2204	response regulator
AB890_RS01085	COG2032	superoxide dismutase activity
AB890_RS01090	COG2032	superoxide dismutase activity
AB890_RS01095	COG0346	lactoylglutathione lyase activity
AB890_RS01105	COG0183	Belongs to the thiolase family
AB890_RS01140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AB890_RS01145	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AB890_RS01150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AB890_RS01165	COG0028	Belongs to the TPP enzyme family
AB890_RS01170	COG2205	protein histidine kinase activity
AB890_RS01195	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AB890_RS01210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AB890_RS01220	COG0596	Alpha beta hydrolase
AB890_RS01225	COG0727	PFAM Uncharacterised protein family (UPF0153)
AB890_RS01230	COG0318	PFAM AMP-dependent synthetase and ligase
AB890_RS01235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB890_RS01250	COG1181	Belongs to the D-alanine--D-alanine ligase family
AB890_RS01260	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AB890_RS01270	COG0564	pseudouridine synthase activity
AB890_RS01295	COG0339	signal peptide processing
AB890_RS01325	COG0475	glutathione-regulated potassium exporter activity
AB890_RS01330	COG0583	DNA-binding transcription factor activity
AB890_RS01335	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AB890_RS01340	COG2224	Isocitrate lyase
AB890_RS01370	COG4770	biotin carboxylase activity
AB890_RS01375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AB890_RS01380	COG1960	acyl-CoA dehydrogenase activity
AB890_RS01435	COG0523	cobalamin synthesis protein
AB890_RS01450	COG0697	spore germination
AB890_RS01460	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AB890_RS01465	COG1846	Transcriptional regulator
AB890_RS01470	COG1764	response to oxidative stress
AB890_RS01500	COG2130	NADP-dependent
AB890_RS01515	COG1187	pseudouridine synthase activity
AB890_RS01530	COG1643	Atp-dependent helicase
AB890_RS01540	COG4807	Protein conserved in bacteria
AB890_RS01545	COG2351	hydroxyisourate hydrolase activity
AB890_RS01550	COG2072	flavoprotein involved in K transport
AB890_RS01570	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AB890_RS01615	COG2252	PERMEase
AB890_RS01640	COG0084	hydrolase, TatD family'
AB890_RS01655	COG0583	DNA-binding transcription factor activity
AB890_RS01660	COG2814	Major facilitator Superfamily
AB890_RS01675	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AB890_RS01680	COG1902	pentaerythritol trinitrate reductase activity
AB890_RS01700	COG0745	RESPONSE REGULATOR receiver
AB890_RS01705	COG2205	protein histidine kinase activity
AB890_RS01710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB890_RS01730	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AB890_RS01735	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AB890_RS01740	COG0583	DNA-binding transcription factor activity
AB890_RS01770	COG0702	epimerase
AB890_RS01775	COG1733	regulation of RNA biosynthetic process
AB890_RS01815	COG0129	dihydroxy-acid dehydratase activity
AB890_RS01835	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AB890_RS01890	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AB890_RS01895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AB890_RS01920	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AB890_RS01925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AB890_RS01935	COG3485	protocatechuate 3,4-dioxygenase
AB890_RS01940	COG3485	protocatechuate 3,4-dioxygenase
AB890_RS01950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AB890_RS01955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AB890_RS01965	COG1414	Transcriptional regulator
AB890_RS01975	COG0657	acetylesterase activity
AB890_RS01985	COG0445	tRNA wobble uridine modification
AB890_RS01995	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AB890_RS02025	COG2267	carboxylic ester hydrolase activity
AB890_RS02035	COG0156	8-amino-7-oxononanoate synthase activity
AB890_RS02040	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AB890_RS02045	COG1040	competence protein
AB890_RS02050	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AB890_RS02125	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AB890_RS02195	COG1511	domain protein
AB890_RS02195	COG3264	Mechanosensitive ion channel
AB890_RS02200	COG1368	sulfuric ester hydrolase activity
AB890_RS02205	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AB890_RS02210	COG2354	Protein conserved in bacteria
AB890_RS02220	COG0297	glycogen (starch) synthase activity
AB890_RS02225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AB890_RS02230	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AB890_RS02255	COG0702	epimerase
AB890_RS02260	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS02295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB890_RS02300	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS02310	COG0513	Belongs to the DEAD box helicase family
AB890_RS02330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AB890_RS02340	COG3483	tryptophan 2,3-dioxygenase activity
AB890_RS02345	COG3104	oligopeptide transport
AB890_RS02365	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AB890_RS02380	COG1320	monovalent cation:proton antiporter activity
AB890_RS02385	COG2212	antiporter activity
AB890_RS02395	COG0651	ATP synthesis coupled electron transport
AB890_RS02400	COG1006	Multisubunit Na H antiporter MnhC subunit
AB890_RS02405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AB890_RS02405	COG2111	Na H antiporter
AB890_RS02425	COG3179	chitinase
AB890_RS02445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AB890_RS02450	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AB890_RS02465	COG0456	acetyltransferase
AB890_RS02470	COG1597	lipid kinase activity
AB890_RS02495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AB890_RS02500	COG0134	indole-3-glycerol-phosphate synthase activity
AB890_RS02510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AB890_RS02515	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AB890_RS02525	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AB890_RS02535	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AB890_RS02550	COG1051	belongs to the nudix hydrolase family
AB890_RS02590	COG0316	Belongs to the HesB IscA family
AB890_RS02615	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AB890_RS02635	COG2814	Major facilitator Superfamily
AB890_RS02640	COG0583	DNA-binding transcription factor activity
AB890_RS02645	COG2814	Major facilitator Superfamily
AB890_RS02650	COG1289	transmembrane transporter activity
AB890_RS02660	COG0151	Belongs to the GarS family
AB890_RS02670	COG0138	bifunctional purine biosynthesis protein purh
AB890_RS02675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AB890_RS02680	COG2267	carboxylic ester hydrolase activity
AB890_RS02685	COG2453	phosphatase
AB890_RS02685	COG0671	phosphoesterase, PA-phosphatase related
AB890_RS02710	COG4589	Belongs to the CDS family
AB890_RS02715	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AB890_RS02740	COG2264	protein methyltransferase activity
AB890_RS02755	COG0439	Biotin carboxylase
AB890_RS02765	COG0511	ligase activity, forming carbon-carbon bonds
AB890_RS02770	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AB890_RS02780	COG1324	tolerance protein
AB890_RS02805	COG0300	oxidoreductase activity
AB890_RS02810	COG2356	endonuclease I
AB890_RS02825	COG0459	protein refolding
AB890_RS02840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AB890_RS02855	COG3386	PFAM SMP-30 Gluconolaconase
AB890_RS02865	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AB890_RS02870	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AB890_RS02890	COG0778	Nitroreductase
AB890_RS02895	COG2353	YceI-like domain
AB890_RS02925	COG3052	prosthetic group binding
AB890_RS02950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AB890_RS02960	COG1802	Transcriptional regulator
AB890_RS03015	COG4221	oxidoreductase activity
AB890_RS03030	COG4221	oxidoreductase activity
AB890_RS03040	COG0435	Glutathione S-transferase
AB890_RS03065	COG2409	Drug exporters of the RND superfamily
AB890_RS03070	COG1506	peptidase
AB890_RS03070	COG0823	Involved in the tonB-independent uptake of proteins
AB890_RS03110	COG0697	spore germination
AB890_RS03125	COG1113	amino acid transport
AB890_RS03145	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AB890_RS03185	COG5001	Diguanylate cyclase
AB890_RS03190	COG0840	transmembrane signaling receptor activity
AB890_RS03195	COG5297	Belongs to the glycosyl hydrolase family 6
AB890_RS03195	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AB890_RS03200	COG0659	secondary active sulfate transmembrane transporter activity
AB890_RS03220	COG2943	transferase activity, transferring hexosyl groups
AB890_RS03230	COG3275	phosphorelay sensor kinase activity
AB890_RS03240	COG0181	hydroxymethylbilane synthase activity
AB890_RS03265	COG1505	serine-type exopeptidase activity
AB890_RS03270	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AB890_RS03275	COG0436	Aminotransferase
AB890_RS03285	COG2832	Protein of unknown function (DUF454)
AB890_RS03295	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AB890_RS03305	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AB890_RS03310	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AB890_RS03315	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AB890_RS03340	COG2226	methyltransferase
AB890_RS03345	COG3300	MHYT domain
AB890_RS03345	COG5001	Diguanylate cyclase
AB890_RS03350	COG0308	aminopeptidase N
AB890_RS03400	COG3284	Transcriptional regulator
AB890_RS03405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AB890_RS03410	COG1077	Cell shape determining protein MreB Mrl
AB890_RS03415	COG1792	Involved in formation and maintenance of cell shape
AB890_RS03430	COG0772	Belongs to the SEDS family
AB890_RS03440	COG2951	lytic endotransglycosylase activity
AB890_RS03445	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AB890_RS03455	COG1686	Belongs to the peptidase S11 family
AB890_RS03465	COG2921	Belongs to the UPF0250 family
AB890_RS03470	COG0321	lipoyl(octanoyl) transferase activity
AB890_RS03475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AB890_RS03490	COG0583	DNA-binding transcription factor activity
AB890_RS03500	COG1051	belongs to the nudix hydrolase family
AB890_RS03500	COG1056	cytidyltransferase-related domain
AB890_RS03535	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AB890_RS03540	COG0673	inositol 2-dehydrogenase activity
AB890_RS03545	COG2823	Periplasmic or secreted lipoprotein
AB890_RS03550	COG4251	negative regulation of phosphorylation
AB890_RS03555	COG0784	Response regulator, receiver
AB890_RS03560	COG4191	Histidine kinase
AB890_RS03565	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AB890_RS03620	COG1459	type II secretion system
AB890_RS03685	COG2188	Transcriptional regulator
AB890_RS03695	COG1609	Transcriptional regulator
AB890_RS03700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AB890_RS03705	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AB890_RS03715	COG0617	tRNA 3'-terminal CCA addition
AB890_RS03720	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AB890_RS03725	COG1012	belongs to the aldehyde dehydrogenase family
AB890_RS03730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AB890_RS03745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AB890_RS03760	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AB890_RS03765	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AB890_RS03810	COG3791	Glutathione-dependent formaldehyde-activating
AB890_RS03825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB890_RS03835	COG0697	spore germination
AB890_RS03845	COG0488	(ABC) transporter
AB890_RS03855	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AB890_RS03860	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AB890_RS03870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AB890_RS03870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AB890_RS03890	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AB890_RS03895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AB890_RS03900	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AB890_RS03920	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AB890_RS03925	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AB890_RS03930	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AB890_RS03935	COG2205	protein histidine kinase activity
AB890_RS03940	COG0745	RESPONSE REGULATOR receiver
AB890_RS03955	COG0277	FAD linked oxidase domain protein
AB890_RS03960	COG1988	membrane-bound metal-dependent
AB890_RS03965	COG0792	nuclease activity
AB890_RS04000	COG0275	rRNA processing
AB890_RS04005	COG3116	cell division
AB890_RS04015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AB890_RS04020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AB890_RS04025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AB890_RS04035	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AB890_RS04040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AB890_RS04045	COG1181	Belongs to the D-alanine--D-alanine ligase family
AB890_RS04050	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AB890_RS04065	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AB890_RS04075	COG0739	heme binding
AB890_RS04080	COG0653	protein targeting
AB890_RS04085	COG0494	nUDIX hydrolase
AB890_RS04095	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AB890_RS04105	COG3321	synthase
AB890_RS04105	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS04105	COG0604	alcohol dehydrogenase
AB890_RS04125	COG0366	Alpha amylase catalytic
AB890_RS04155	COG2226	methyltransferase
AB890_RS04160	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AB890_RS04170	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AB890_RS04205	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AB890_RS04215	COG4106	trans-aconitate 2-methyltransferase activity
AB890_RS04220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AB890_RS04230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AB890_RS04235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AB890_RS04240	COG0667	Aldo Keto reductase
AB890_RS04250	COG4771	TonB-dependent receptor
AB890_RS04270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB890_RS04275	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AB890_RS04285	COG2175	clavaminate synthase activity
AB890_RS04295	COG4181	ATPase activity
AB890_RS04310	COG0642	Histidine kinase
AB890_RS04320	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AB890_RS04340	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AB890_RS04345	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AB890_RS04360	COG3829	transcription factor binding
AB890_RS04370	COG1116	anion transmembrane transporter activity
AB890_RS04375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB890_RS04385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB890_RS04390	COG0431	NADPH-dependent FMN reductase
AB890_RS04415	COG0747	negative chemotaxis
AB890_RS04425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AB890_RS04435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AB890_RS04440	COG2967	ApaG domain
AB890_RS04445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AB890_RS04450	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AB890_RS04455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AB890_RS04460	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AB890_RS04470	COG0123	including yeast histone deacetylase and acetoin utilization protein
AB890_RS04475	COG2096	Adenosyltransferase
AB890_RS04490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB890_RS04495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB890_RS04525	COG3384	dioxygenase
AB890_RS04530	COG0583	DNA-binding transcription factor activity
AB890_RS04545	COG1024	Enoyl-CoA hydratase
AB890_RS04565	COG3386	PFAM SMP-30 Gluconolaconase
AB890_RS04580	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AB890_RS04610	COG0697	spore germination
AB890_RS04620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AB890_RS04640	COG2205	protein histidine kinase activity
AB890_RS04640	COG5002	protein histidine kinase activity
AB890_RS04640	COG0784	Response regulator, receiver
AB890_RS04645	COG2197	response regulator
AB890_RS04655	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AB890_RS04665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AB890_RS04670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AB890_RS04675	COG0583	DNA-binding transcription factor activity
AB890_RS04680	COG3634	alkyl hydroperoxide reductase activity
AB890_RS04690	COG2890	protein-(glutamine-N5) methyltransferase activity
AB890_RS04710	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB890_RS04710	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB890_RS04740	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AB890_RS04770	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AB890_RS04785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AB890_RS04790	COG1404	Belongs to the peptidase S8 family
AB890_RS04800	COG1404	Belongs to the peptidase S8 family
AB890_RS04805	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AB890_RS04830	COG1295	ribonuclease BN
AB890_RS04835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB890_RS04855	COG0521	Mo-molybdopterin cofactor biosynthetic process
AB890_RS04865	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AB890_RS04880	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AB890_RS04885	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AB890_RS04895	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AB890_RS04900	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AB890_RS04905	COG0193	aminoacyl-tRNA hydrolase activity
AB890_RS04910	COG0012	GTP binding
AB890_RS04930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AB890_RS04945	COG0250	Participates in transcription elongation, termination and antitermination
AB890_RS04950	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AB890_RS04955	COG0081	regulation of translation
AB890_RS04960	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AB890_RS04965	COG0222	ribosome binding
AB890_RS04970	COG0085	RNA polymerase activity
AB890_RS04975	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AB890_RS04980	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AB890_RS04985	COG0049	tRNA binding
AB890_RS04990	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AB890_RS04995	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AB890_RS05000	COG0051	transcription antitermination factor activity, RNA binding
AB890_RS05005	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AB890_RS05010	COG0088	Forms part of the polypeptide exit tunnel
AB890_RS05015	COG0089	rRNA binding
AB890_RS05020	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AB890_RS05025	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AB890_RS05035	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AB890_RS05040	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AB890_RS05045	COG0255	Belongs to the universal ribosomal protein uL29 family
AB890_RS05050	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AB890_RS05060	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AB890_RS05065	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AB890_RS05075	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AB890_RS05080	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AB890_RS05085	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AB890_RS05095	COG1841	ribosomal large subunit assembly
AB890_RS05100	COG0200	Binds to the 23S rRNA
AB890_RS05105	COG0201	protein transport
AB890_RS05130	COG0203	ribosomal protein L17
AB890_RS05135	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AB890_RS05150	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AB890_RS05160	COG0154	amidase activity
AB890_RS05170	COG1217	gtp-binding protein TYPA
AB890_RS05175	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AB890_RS05180	COG0039	L-malate dehydrogenase activity
AB890_RS05185	COG0625	glutathione transferase activity
AB890_RS05195	COG0446	pyridine nucleotide-disulphide oxidoreductase
AB890_RS05195	COG1902	pentaerythritol trinitrate reductase activity
AB890_RS05200	COG0604	alcohol dehydrogenase
AB890_RS05225	COG0156	8-amino-7-oxononanoate synthase activity
AB890_RS05230	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AB890_RS05235	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AB890_RS05240	COG4208	sulfate ABC transporter
AB890_RS05245	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AB890_RS05255	COG1063	alcohol dehydrogenase
AB890_RS05285	COG0406	alpha-ribazole phosphatase activity
AB890_RS05290	COG0285	dihydrofolate synthase activity
AB890_RS05310	COG2833	Protein of unknown function (DUF455)
AB890_RS05320	COG3291	Pkd domain containing protein
AB890_RS05330	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AB890_RS05335	COG0671	phosphoesterase, PA-phosphatase related
AB890_RS05340	COG0438	transferase activity, transferring glycosyl groups
AB890_RS05350	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AB890_RS05365	COG4783	chaperone-mediated protein folding
AB890_RS05380	COG0473	3-isopropylmalate dehydrogenase activity
AB890_RS05530	COG0544	peptidyl-prolyl cis-trans isomerase activity
AB890_RS05540	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AB890_RS05570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AB890_RS05580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB890_RS05590	COG0328	RNA-DNA hybrid ribonuclease activity
AB890_RS05595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AB890_RS05600	COG0631	protein serine/threonine phosphatase activity
AB890_RS05615	COG0859	PFAM glycosyl transferase family 9
AB890_RS05620	COG3642	lipopolysaccharide core region biosynthetic process
AB890_RS05625	COG1234	tRNA 3'-trailer cleavage
AB890_RS05630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AB890_RS05640	COG0315	cyclic pyranopterin monophosphate synthase activity
AB890_RS05645	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AB890_RS05650	COG0314	molybdopterin synthase activity
AB890_RS05705	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AB890_RS05710	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AB890_RS05715	COG0537	adenosine 5'-monophosphoramidase activity
AB890_RS05735	COG0714	Associated with various cellular activities
AB890_RS05755	COG0424	maF-like protein
AB890_RS05760	COG1399	metal-binding, possibly nucleic acid-binding protein
AB890_RS05765	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AB890_RS05770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AB890_RS05785	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS05800	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AB890_RS05805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AB890_RS05830	COG3829	transcription factor binding
AB890_RS05850	COG3609	addiction module antidote protein, CC2985 family
AB890_RS05870	COG2373	Large extracellular alpha-helical protein
AB890_RS05885	COG4953	penicillin-binding protein 1C
AB890_RS05895	COG0678	peroxiredoxin activity
AB890_RS05915	COG0330	HflC and HflK could
AB890_RS05920	COG0330	HflC and HflK could
AB890_RS05930	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AB890_RS05935	COG0308	aminopeptidase N
AB890_RS05945	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS05950	COG1309	transcriptional regulator
AB890_RS06020	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AB890_RS06030	COG3387	PFAM Glycoside hydrolase 15-related
AB890_RS06035	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS06040	COG3537	Alpha-1,2-mannosidase
AB890_RS06060	COG0492	ferredoxin-NADP+ reductase activity
AB890_RS06085	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AB890_RS06090	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AB890_RS06095	COG2080	2 iron, 2 sulfur cluster binding
AB890_RS06130	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AB890_RS06145	COG0587	DNA-directed DNA polymerase activity
AB890_RS06160	COG1297	OPT oligopeptide transporter protein
AB890_RS06180	COG0823	Involved in the tonB-independent uptake of proteins
AB890_RS06180	COG1506	peptidase
AB890_RS06195	COG2207	Transcriptional regulator
AB890_RS06195	COG1917	Cupin 2, conserved barrel domain protein
AB890_RS06210	COG0753	catalase activity
AB890_RS06215	COG0656	L-ascorbic acid biosynthetic process
AB890_RS06225	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AB890_RS06225	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AB890_RS06230	COG2814	Major facilitator Superfamily
AB890_RS06245	COG2194	sulfuric ester hydrolase activity
AB890_RS06260	COG0745	RESPONSE REGULATOR receiver
AB890_RS06265	COG0642	Histidine kinase
AB890_RS06275	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AB890_RS06280	COG2894	cell division
AB890_RS06285	COG0850	regulation of cytokinetic process
AB890_RS06300	COG4585	Histidine kinase
AB890_RS06305	COG2197	response regulator
AB890_RS06320	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AB890_RS06345	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AB890_RS06355	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AB890_RS06375	COG1946	Acyl-CoA thioesterase
AB890_RS06390	COG0824	Thioesterase
AB890_RS06395	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AB890_RS06400	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AB890_RS06405	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AB890_RS06410	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AB890_RS06415	COG0268	Binds directly to 16S ribosomal RNA
AB890_RS06425	COG0196	riboflavin kinase activity
AB890_RS06430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AB890_RS06435	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AB890_RS06440	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AB890_RS06455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AB890_RS06460	COG1845	cytochrome c oxidase, subunit III
AB890_RS06465	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AB890_RS06480	COG3152	Membrane
AB890_RS06490	COG2207	Transcriptional regulator
AB890_RS06495	COG0326	Molecular chaperone. Has ATPase activity
AB890_RS06505	COG1366	Belongs to the anti-sigma-factor antagonist family
AB890_RS06510	COG1366	Belongs to the anti-sigma-factor antagonist family
AB890_RS06515	COG2172	sigma factor antagonist activity
AB890_RS06540	COG4771	TonB-dependent receptor
AB890_RS06550	COG5507	3-demethylubiquinone-9 3-methyltransferase
AB890_RS06555	COG2205	protein histidine kinase activity
AB890_RS06565	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AB890_RS06570	COG3437	response regulator, receiver
AB890_RS06570	COG2205	protein histidine kinase activity
AB890_RS06570	COG3850	Histidine kinase
AB890_RS06570	COG4999	Histidine kinase
AB890_RS06575	COG4191	Histidine kinase
AB890_RS06575	COG0784	Response regulator, receiver
AB890_RS06605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AB890_RS06610	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AB890_RS06620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AB890_RS06625	COG0228	four-way junction DNA binding
AB890_RS06630	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AB890_RS06635	COG0336	Belongs to the RNA methyltransferase TrmD family
AB890_RS06640	COG0335	large ribosomal subunit rRNA binding
AB890_RS06670	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AB890_RS06680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AB890_RS06690	COG3209	COG3209 Rhs family protein
AB890_RS06710	COG3250	beta-galactosidase activity
AB890_RS06715	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AB890_RS06735	COG1960	acyl-CoA dehydrogenase activity
AB890_RS06740	COG1024	Enoyl-CoA hydratase
AB890_RS06760	COG1024	Enoyl-CoA hydratase
AB890_RS06760	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB890_RS06775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB890_RS06780	COG0481	GTPase activity
AB890_RS06795	COG0571	ribonuclease III activity
AB890_RS06800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AB890_RS06805	COG1381	Involved in DNA repair and RecF pathway recombination
AB890_RS06815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AB890_RS06820	COG2954	triphosphatase activity
AB890_RS06825	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AB890_RS06830	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AB890_RS06835	COG3046	protein related to deoxyribodipyrimidine photolyase
AB890_RS06840	COG1472	Belongs to the glycosyl hydrolase 3 family
AB890_RS06845	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AB890_RS06850	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AB890_RS06855	COG1278	Cold shock
AB890_RS06860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB890_RS06870	COG1201	RNA secondary structure unwinding
AB890_RS06875	COG1793	dna ligase
AB890_RS06885	COG1793	dna ligase
AB890_RS06885	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AB890_RS06915	COG0183	Belongs to the thiolase family
AB890_RS06940	COG1451	nucleotide metabolic process
AB890_RS06945	COG5487	UPF0391 membrane protein
AB890_RS06955	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AB890_RS06975	COG1077	Cell shape determining protein MreB Mrl
AB890_RS06980	COG1047	Peptidyl-prolyl cis-trans
AB890_RS06990	COG2824	Alkylphosphonate utilization operon protein PhnA
AB890_RS06995	COG1902	pentaerythritol trinitrate reductase activity
AB890_RS07000	COG2814	Major facilitator Superfamily
AB890_RS07035	COG0392	lysyltransferase activity
AB890_RS07035	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AB890_RS07045	COG0251	oxidation-reduction process
AB890_RS07050	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AB890_RS07065	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AB890_RS07090	COG1595	DNA-templated transcription, initiation
AB890_RS07110	COG2878	Part of a membrane complex involved in electron transport
AB890_RS07120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB890_RS07120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB890_RS07135	COG1131	(ABC) transporter
AB890_RS07140	COG0346	lactoylglutathione lyase activity
AB890_RS07145	COG0833	amino acid
AB890_RS07150	COG2040	homocysteine
AB890_RS07160	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AB890_RS07180	COG1695	Transcriptional regulator
AB890_RS07200	COG1981	membrane
AB890_RS07215	COG0825	malonyl-CoA metabolic process
AB890_RS07225	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AB890_RS07230	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AB890_RS07235	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AB890_RS07240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AB890_RS07245	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AB890_RS07260	COG0750	zinc metalloprotease
AB890_RS07265	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AB890_RS07270	COG0575	Belongs to the CDS family
AB890_RS07275	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AB890_RS07280	COG0233	cytoplasmic translational termination
AB890_RS07285	COG0528	UMP kinase activity
AB890_RS07295	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AB890_RS07300	COG0052	Belongs to the universal ribosomal protein uS2 family
AB890_RS07340	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AB890_RS07350	COG1393	Belongs to the ArsC family
AB890_RS07355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AB890_RS07360	COG0367	asparagine synthase
AB890_RS07370	COG4774	siderophore transport
AB890_RS07390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AB890_RS07425	COG1566	PFAM secretion protein HlyD family protein
AB890_RS07430	COG2814	Major facilitator Superfamily
AB890_RS07480	COG0339	signal peptide processing
AB890_RS07485	COG0386	Belongs to the glutathione peroxidase family
AB890_RS07540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AB890_RS07545	COG0084	hydrolase, TatD family'
AB890_RS07560	COG1960	acyl-CoA dehydrogenase activity
AB890_RS07575	COG0367	asparagine synthase
AB890_RS07585	COG0305	Participates in initiation and elongation during chromosome replication
AB890_RS07590	COG0415	Belongs to the DNA photolyase family
AB890_RS07600	COG0583	DNA-binding transcription factor activity
AB890_RS07645	COG3706	GGDEF domain
AB890_RS07755	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AB890_RS07770	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AB890_RS07780	COG0497	DNA recombination
AB890_RS07785	COG1420	regulation of RNA biosynthetic process
AB890_RS07790	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AB890_RS07795	COG0443	Heat shock 70 kDa protein
AB890_RS07800	COG0484	heat shock protein binding
AB890_RS07805	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AB890_RS07835	COG0583	DNA-binding transcription factor activity
AB890_RS07840	COG1132	(ABC) transporter
AB890_RS07875	COG2850	peptidyl-arginine hydroxylation
AB890_RS07895	COG1253	flavin adenine dinucleotide binding
AB890_RS07925	COG1131	(ABC) transporter
AB890_RS07930	COG1725	Transcriptional regulator
AB890_RS07935	COG0386	Belongs to the glutathione peroxidase family
AB890_RS07950	COG2900	Belongs to the SlyX family
AB890_RS07975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AB890_RS07985	COG1410	methionine synthase
AB890_RS07985	COG0646	methionine synthase
AB890_RS07990	COG0646	methionine synthase
AB890_RS07990	COG1410	methionine synthase
AB890_RS07995	COG2226	methyltransferase
AB890_RS08000	COG1960	acyl-CoA dehydrogenase activity
AB890_RS08015	COG0557	exoribonuclease II activity
AB890_RS08025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB890_RS08035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AB890_RS08045	COG0704	Plays a role in the regulation of phosphate uptake
AB890_RS08050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AB890_RS08055	COG0581	inorganic phosphate transmembrane transporter activity
AB890_RS08060	COG0573	inorganic phosphate transmembrane transporter activity
AB890_RS08065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AB890_RS08090	COG0659	secondary active sulfate transmembrane transporter activity
AB890_RS08095	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AB890_RS08105	COG1024	Enoyl-CoA hydratase
AB890_RS08115	COG0494	nUDIX hydrolase
AB890_RS08150	COG0488	(ABC) transporter
AB890_RS08155	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AB890_RS08155	COG0116	Belongs to the methyltransferase superfamily
AB890_RS08160	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AB890_RS08185	COG2925	Exonuclease
AB890_RS08195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB890_RS08200	COG3844	kynureninase activity
AB890_RS08210	COG0662	Cupin 2, conserved barrel domain protein
AB890_RS08215	COG0288	reversible hydration of carbon dioxide
AB890_RS08280	COG2808	Putative FMN-binding domain
AB890_RS08300	COG0017	Asparaginyl-tRNA synthetase
AB890_RS08305	COG0316	Belongs to the HesB IscA family
AB890_RS08310	COG0360	Binds together with S18 to 16S ribosomal RNA
AB890_RS08315	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AB890_RS08320	COG0359	binds to the 23S rRNA
AB890_RS08330	COG3115	cell septum assembly
AB890_RS08340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AB890_RS08345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AB890_RS08350	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AB890_RS08365	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AB890_RS08375	COG4993	Dehydrogenase
AB890_RS08385	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AB890_RS08395	COG2986	histidine ammonia-lyase
AB890_RS08400	COG1228	amidohydrolase
AB890_RS08445	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AB890_RS08450	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AB890_RS08455	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AB890_RS08460	COG1605	Chorismate mutase
AB890_RS08460	COG0077	Prephenate dehydratase
AB890_RS08465	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AB890_RS08480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AB890_RS08485	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AB890_RS08490	COG0583	DNA-binding transcription factor activity
AB890_RS08505	COG0840	transmembrane signaling receptor activity
AB890_RS08540	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AB890_RS08545	COG4191	Histidine kinase
AB890_RS08545	COG0784	Response regulator, receiver
AB890_RS08560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB890_RS08570	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AB890_RS08580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AB890_RS08595	COG1595	DNA-templated transcription, initiation
AB890_RS08650	COG2244	polysaccharide biosynthetic process
AB890_RS08680	COG2264	protein methyltransferase activity
AB890_RS08690	COG0438	transferase activity, transferring glycosyl groups
AB890_RS08705	COG1136	(ABC) transporter
AB890_RS08715	COG0477	Major facilitator Superfamily
AB890_RS08720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB890_RS08735	COG1253	flavin adenine dinucleotide binding
AB890_RS08745	COG0306	phosphate transporter
AB890_RS08770	COG0504	CTP synthase activity
AB890_RS08775	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AB890_RS08785	COG0148	phosphopyruvate hydratase activity
AB890_RS08790	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AB890_RS08795	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AB890_RS08800	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AB890_RS08805	COG0585	pseudouridine synthase activity
AB890_RS08810	COG2840	Smr protein MutS2
AB890_RS08815	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AB890_RS08820	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AB890_RS08825	COG1238	metal cluster binding
AB890_RS08840	COG1534	Rna-binding protein
AB890_RS08845	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AB890_RS08855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AB890_RS08860	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AB890_RS08870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AB890_RS08875	COG1546	Belongs to the CinA family
AB890_RS08885	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AB890_RS08890	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AB890_RS08895	COG2137	regulation of response to DNA damage stimulus
AB890_RS08900	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AB890_RS08905	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AB890_RS08920	COG1741	Belongs to the pirin family
AB890_RS08930	COG0583	DNA-binding transcription factor activity
AB890_RS08955	COG0352	thiamine-phosphate diphosphorylase activity
AB890_RS08955	COG0351	phosphomethylpyrimidine kinase
AB890_RS08970	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AB890_RS08975	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AB890_RS08990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB890_RS09000	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AB890_RS09005	COG3734	2-keto-3-deoxy-galactonokinase
AB890_RS09015	COG4948	Mandelate Racemase Muconate Lactonizing
AB890_RS09020	COG0800	Aldolase
AB890_RS09060	COG1501	Belongs to the glycosyl hydrolase 31 family
AB890_RS09070	COG1070	Carbohydrate kinase
AB890_RS09075	COG2115	Belongs to the xylose isomerase family
AB890_RS09080	COG0477	Major facilitator Superfamily
AB890_RS09090	COG0860	N-Acetylmuramoyl-L-alanine amidase
AB890_RS09095	COG1469	GTP cyclohydrolase I activity
AB890_RS09115	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AB890_RS09120	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AB890_RS09125	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AB890_RS09130	COG0166	Belongs to the GPI family
AB890_RS09150	COG1472	Belongs to the glycosyl hydrolase 3 family
AB890_RS09160	COG4251	negative regulation of phosphorylation
AB890_RS09160	COG3706	GGDEF domain
AB890_RS09160	COG2203	Gaf domain
AB890_RS09160	COG5001	Diguanylate cyclase
AB890_RS09165	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AB890_RS09170	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AB890_RS09180	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AB890_RS09185	COG0671	phosphoesterase, PA-phosphatase related
AB890_RS09200	COG1794	racemase activity, acting on amino acids and derivatives
AB890_RS09205	COG0697	spore germination
AB890_RS09210	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AB890_RS09215	COG0167	dihydroorotate dehydrogenase activity
AB890_RS09230	COG1012	belongs to the aldehyde dehydrogenase family
AB890_RS09245	COG1215	transferase activity, transferring glycosyl groups
AB890_RS09250	COG1649	PFAM Uncharacterised BCR, COG1649
AB890_RS09250	COG0726	polysaccharide deacetylase
AB890_RS09265	COG3210	domain, Protein
AB890_RS09270	COG3210	domain, Protein
AB890_RS09310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AB890_RS09315	COG0124	histidyl-tRNA synthetase
AB890_RS09325	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AB890_RS09330	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AB890_RS09335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AB890_RS09340	COG0131	Imidazoleglycerol-phosphate dehydratase
AB890_RS09340	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AB890_RS09345	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AB890_RS09350	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AB890_RS09355	COG0107	imidazoleglycerol-phosphate synthase activity
AB890_RS09360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AB890_RS09360	COG0140	phosphoribosyl-ATP diphosphatase activity
AB890_RS09375	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AB890_RS09380	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AB890_RS09385	COG0235	Class ii aldolase
AB890_RS09390	COG0531	amino acid
AB890_RS09395	COG0531	amino acid
AB890_RS09405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AB890_RS09410	COG0277	FAD linked oxidase domain protein
AB890_RS09430	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AB890_RS09475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB890_RS09480	COG2258	MOSC domain
AB890_RS09485	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AB890_RS09490	COG0505	Belongs to the CarA family
AB890_RS09500	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AB890_RS09505	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AB890_RS09515	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AB890_RS09560	COG3279	Response regulator of the LytR AlgR family
AB890_RS09565	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AB890_RS09570	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AB890_RS09580	COG2198	Histidine kinase
AB890_RS09580	COG2205	protein histidine kinase activity
AB890_RS09580	COG0784	Response regulator, receiver
AB890_RS09585	COG1024	Enoyl-CoA hydratase
AB890_RS09590	COG0318	PFAM AMP-dependent synthetase and ligase
AB890_RS09620	COG2267	carboxylic ester hydrolase activity
AB890_RS09630	COG2201	protein-glutamate methylesterase activity
AB890_RS09635	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AB890_RS09645	COG0840	transmembrane signaling receptor activity
AB890_RS09650	COG0840	transmembrane signaling receptor activity
AB890_RS09655	COG0840	transmembrane signaling receptor activity
AB890_RS09665	COG0840	transmembrane signaling receptor activity
AB890_RS09670	COG0840	transmembrane signaling receptor activity
AB890_RS09680	COG0840	transmembrane signaling receptor activity
AB890_RS09695	COG0840	transmembrane signaling receptor activity
AB890_RS09710	COG0840	transmembrane signaling receptor activity
AB890_RS09715	COG2198	Histidine kinase
AB890_RS09715	COG0643	Histidine kinase
AB890_RS09720	COG0745	RESPONSE REGULATOR receiver
AB890_RS09730	COG0835	chemotaxis
AB890_RS09740	COG1360	Flagellar Motor Protein
AB890_RS09745	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AB890_RS09825	COG0641	radical SAM
AB890_RS09840	COG0643	Histidine kinase
AB890_RS09840	COG0784	Response regulator, receiver
AB890_RS09840	COG2198	Histidine kinase
AB890_RS09870	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AB890_RS09900	COG1684	flagellar biosynthetic protein fliR
AB890_RS09915	COG3190	flagellar
AB890_RS09965	COG1677	Flagellar hook-basal body complex protein FliE
AB890_RS09995	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS10000	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS10005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AB890_RS10025	COG2201	protein-glutamate methylesterase activity
AB890_RS10055	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AB890_RS10060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AB890_RS10065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AB890_RS10075	COG3951	Flagellar rod assembly protein muramidase FlgJ
AB890_RS10075	COG1705	Flagellar rod assembly protein muramidase FlgJ
AB890_RS10080	COG1706	bacterial-type flagellum-dependent cell motility
AB890_RS10085	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AB890_RS10095	COG4787	bacterial-type flagellum-dependent cell motility
AB890_RS10105	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AB890_RS10110	COG1558	bacterial-type flagellum-dependent cell motility
AB890_RS10120	COG0784	Response regulator, receiver
AB890_RS10120	COG0835	chemotaxis
AB890_RS10140	COG5002	protein histidine kinase activity
AB890_RS10170	COG2915	High frequency lysogenization protein hflD homolog
AB890_RS10175	COG0482	sulfurtransferase activity
AB890_RS10190	COG0542	response to heat
AB890_RS10200	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AB890_RS10210	COG0492	ferredoxin-NADP+ reductase activity
AB890_RS10215	COG1674	ftsk spoiiie
AB890_RS10225	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AB890_RS10235	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AB890_RS10240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AB890_RS10250	COG0183	Belongs to the thiolase family
AB890_RS10255	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB890_RS10255	COG1024	Enoyl-CoA hydratase
AB890_RS10270	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AB890_RS10280	COG1426	Protein conserved in bacteria
AB890_RS10290	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AB890_RS10295	COG1160	GTP binding
AB890_RS10300	COG0303	'Molybdopterin
AB890_RS10305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AB890_RS10340	COG0708	Exodeoxyribonuclease III
AB890_RS10350	COG0303	'Molybdopterin
AB890_RS10355	COG0746	molybdenum cofactor guanylyltransferase activity
AB890_RS10370	COG1914	H( )-stimulated, divalent metal cation uptake system
AB890_RS10385	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AB890_RS10390	COG0668	transmembrane transport
AB890_RS10400	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AB890_RS10415	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS10420	COG1183	phosphatidylcholine synthase activity
AB890_RS10430	COG3243	poly(R)-hydroxyalkanoic acid synthase
AB890_RS10445	COG0723	plastoquinol--plastocyanin reductase activity
AB890_RS10445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB890_RS10455	COG2183	response to ionizing radiation
AB890_RS10460	COG2205	protein histidine kinase activity
AB890_RS10460	COG0784	Response regulator, receiver
AB890_RS10525	COG0800	Aldolase
AB890_RS10530	COG0129	dihydroxy-acid dehydratase activity
AB890_RS10535	COG0363	glucosamine-6-phosphate deaminase activity
AB890_RS10540	COG0837	glucose binding
AB890_RS10545	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AB890_RS10565	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AB890_RS10580	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AB890_RS10585	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AB890_RS10595	COG4591	ABC-type transport system involved in lipoprotein release permease component
AB890_RS10600	COG1136	(ABC) transporter
AB890_RS10615	COG0811	peptide transport
AB890_RS10625	COG1132	(ABC) transporter
AB890_RS10630	COG1663	tetraacyldisaccharide 4'-kinase activity
AB890_RS10635	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AB890_RS10640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AB890_RS10650	COG0322	excinuclease ABC activity
AB890_RS10655	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AB890_RS10675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AB890_RS10710	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AB890_RS10730	COG1054	Belongs to the UPF0176 family
AB890_RS10740	COG1530	ribonuclease E activity
AB890_RS10750	COG3064	Membrane
AB890_RS10755	COG0428	transporter
AB890_RS10765	COG2154	pterin-4-alpha-carbinolamine dehydratase
AB890_RS10770	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AB890_RS10770	COG0316	Belongs to the HesB IscA family
AB890_RS10815	COG1073	alpha beta
AB890_RS10815	COG2226	methyltransferase
AB890_RS10825	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS10850	COG1238	metal cluster binding
AB890_RS10890	COG3279	Response regulator of the LytR AlgR family
AB890_RS10935	COG4566	intracellular signal transduction
AB890_RS10945	COG5001	Diguanylate cyclase
AB890_RS10965	COG3685	Protein conserved in bacteria
AB890_RS10980	COG1648	precorrin-2 dehydrogenase activity
AB890_RS10980	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AB890_RS10995	COG2814	Major facilitator Superfamily
AB890_RS11015	COG1335	isochorismatase
AB890_RS11030	COG2197	response regulator
AB890_RS11050	COG0583	DNA-binding transcription factor activity
AB890_RS11055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AB890_RS11060	COG3002	Belongs to the UPF0753 family
AB890_RS11070	COG1396	sequence-specific DNA binding
AB890_RS11075	COG5489	Protein of unknown function (DUF736)
AB890_RS11080	COG2003	Belongs to the UPF0758 family
AB890_RS11105	COG0582	viral genome integration into host DNA
AB890_RS11120	COG4774	siderophore transport
AB890_RS11135	COG2336	PFAM SpoVT AbrB
AB890_RS11160	COG4206	TonB-dependent receptor
AB890_RS11205	COG2274	protein secretion by the type I secretion system
AB890_RS11260	COG0270	DNA (cytosine-5-)-methyltransferase activity
AB890_RS11310	COG4804	nuclease activity
AB890_RS11320	COG5006	permease, DMT superfamily
AB890_RS11335	COG2249	NAD(P)H dehydrogenase (quinone) activity
AB890_RS11345	COG3938	Belongs to the proline racemase family
AB890_RS11360	COG2807	transmembrane transport
AB890_RS11365	COG2207	Transcriptional regulator
AB890_RS11515	COG0210	DNA helicase
AB890_RS11595	COG2084	Dehydrogenase
AB890_RS11615	COG2003	Belongs to the UPF0758 family
AB890_RS11650	COG0582	viral genome integration into host DNA
AB890_RS11655	COG0519	Catalyzes the synthesis of GMP from XMP
AB890_RS11655	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AB890_RS11665	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AB890_RS11675	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AB890_RS11675	COG0475	glutathione-regulated potassium exporter activity
AB890_RS11680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AB890_RS11690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AB890_RS11695	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AB890_RS11705	COG0776	regulation of translation
AB890_RS11710	COG0539	negative regulation of cytoplasmic translation
AB890_RS11715	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AB890_RS11730	COG2957	Belongs to the agmatine deiminase family
AB890_RS11735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AB890_RS11760	COG0395	ABC-type sugar transport system, permease component
AB890_RS11765	COG1175	transmembrane transport
AB890_RS11795	COG2350	Protein conserved in bacteria
AB890_RS11800	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AB890_RS11805	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AB890_RS11810	COG1187	pseudouridine synthase activity
AB890_RS11830	COG0436	Aminotransferase
AB890_RS11835	COG4133	protoheme IX ABC transporter activity
AB890_RS11855	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AB890_RS11860	COG1138	Cytochrome C-type biogenesis protein
AB890_RS11880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AB890_RS11885	COG1278	Cold shock
AB890_RS11890	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AB890_RS11895	COG4988	ABC transporter
AB890_RS11905	COG1294	oxidase, subunit
AB890_RS11930	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AB890_RS11935	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AB890_RS11945	COG0165	Argininosuccinate lyase
AB890_RS11950	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AB890_RS11960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AB890_RS11965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AB890_RS11975	COG0137	argininosuccinate synthase activity
AB890_RS11980	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AB890_RS11990	COG0215	cysteine-tRNA ligase activity
AB890_RS11995	COG2166	iron-sulfur cluster assembly
AB890_RS12010	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AB890_RS12015	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AB890_RS12040	COG4302	ethanolamine ammonia-lyase activity
AB890_RS12070	COG2963	transposase activity
AB890_RS12090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AB890_RS12095	COG0402	S-adenosylhomocysteine deaminase activity
AB890_RS12105	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AB890_RS12110	COG1509	lysine 2,3-aminomutase activity
AB890_RS12115	COG5001	Diguanylate cyclase
AB890_RS12115	COG3300	MHYT domain
AB890_RS12130	COG0483	inositol monophosphate 1-phosphatase activity
AB890_RS12135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AB890_RS12150	COG0488	(ABC) transporter
AB890_RS12155	COG0513	Belongs to the DEAD box helicase family
AB890_RS12160	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AB890_RS12165	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AB890_RS12175	COG0625	glutathione transferase activity
AB890_RS12185	COG4681	YaeQ
AB890_RS12190	COG2081	HI0933 family
AB890_RS12200	COG0501	Belongs to the peptidase M48B family
AB890_RS12205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AB890_RS12210	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS12235	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AB890_RS12240	COG0860	N-Acetylmuramoyl-L-alanine amidase
AB890_RS12245	COG0802	atpase or kinase
AB890_RS12250	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AB890_RS12250	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AB890_RS12255	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AB890_RS12260	COG1570	exodeoxyribonuclease VII activity
AB890_RS12270	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AB890_RS12455	COG0835	chemotaxis
AB890_RS12460	COG0840	transmembrane signaling receptor activity
AB890_RS12465	COG2094	Belongs to the DNA glycosylase MPG family
AB890_RS12470	COG1201	RNA secondary structure unwinding
AB890_RS12490	COG2969	positive regulation of protein catabolic process
AB890_RS12495	COG0625	glutathione transferase activity
AB890_RS12500	COG2857	Cytochrome c1
AB890_RS12505	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AB890_RS12510	COG0723	plastoquinol--plastocyanin reductase activity
AB890_RS12515	COG0741	lytic transglycosylase activity
AB890_RS12530	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AB890_RS12535	COG1702	phosphate starvation-inducible protein PhoH
AB890_RS12545	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AB890_RS12555	COG4535	Mg2 and Co2 transporter CorC
AB890_RS12570	COG1012	belongs to the aldehyde dehydrogenase family
AB890_RS12580	COG1177	transmembrane transport
AB890_RS12585	COG1176	ABC-type spermidine putrescine transport system, permease component I
AB890_RS12590	COG3842	ATPase activity
AB890_RS12610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AB890_RS12625	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AB890_RS12630	COG0174	glutamine synthetase
AB890_RS12635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB890_RS12645	COG2703	oxygen carrier activity
AB890_RS12650	COG0477	Major facilitator Superfamily
AB890_RS12660	COG0243	molybdopterin cofactor binding
AB890_RS12665	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AB890_RS12670	COG2223	nitrite transmembrane transporter activity
AB890_RS12680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AB890_RS12690	COG2733	membrane
AB890_RS12695	COG5002	protein histidine kinase activity
AB890_RS12695	COG0784	Response regulator, receiver
AB890_RS12695	COG2205	protein histidine kinase activity
AB890_RS12705	COG0477	Major facilitator Superfamily
AB890_RS12710	COG2902	Dehydrogenase
AB890_RS12720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB890_RS12725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB890_RS12730	COG1609	Transcriptional regulator
AB890_RS12735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AB890_RS12735	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB890_RS12740	COG1105	Belongs to the carbohydrate kinase PfkB family
AB890_RS12745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AB890_RS12745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AB890_RS12780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AB890_RS12790	COG1862	Preprotein translocase
AB890_RS12795	COG0343	queuine tRNA-ribosyltransferase activity
AB890_RS12800	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AB890_RS12840	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AB890_RS12845	COG3291	Pkd domain containing protein
AB890_RS12855	COG0405	Gamma-glutamyltransferase
AB890_RS12860	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AB890_RS12875	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AB890_RS12880	COG0742	ribosomal rna small subunit methyltransferase
AB890_RS12885	COG0326	Molecular chaperone. Has ATPase activity
AB890_RS12960	COG0531	amino acid
AB890_RS12975	COG0006	proline dipeptidase activity
AB890_RS12985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB890_RS13000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB890_RS13005	COG3938	Belongs to the proline racemase family
AB890_RS13015	COG0552	protein localization to endoplasmic reticulum
AB890_RS13020	COG1194	a g-specific adenine glycosylase
AB890_RS13025	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AB890_RS13030	COG0784	Response regulator, receiver
AB890_RS13030	COG4191	Histidine kinase
AB890_RS13045	COG0322	excinuclease ABC activity
AB890_RS13060	COG3040	lipid binding
AB890_RS13075	COG1960	acyl-CoA dehydrogenase activity
AB890_RS13085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AB890_RS13105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB890_RS13110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB890_RS13115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AB890_RS13140	COG0438	transferase activity, transferring glycosyl groups
AB890_RS13150	COG0438	transferase activity, transferring glycosyl groups
AB890_RS13155	COG0438	transferase activity, transferring glycosyl groups
AB890_RS13205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB890_RS13205	COG0072	phenylalanine-tRNA ligase activity
AB890_RS13210	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AB890_RS13225	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AB890_RS13230	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AB890_RS13255	COG1082	Xylose isomerase domain protein TIM barrel
AB890_RS13270	COG0366	Alpha amylase catalytic
AB890_RS13320	COG3702	type iv secretory pathway
AB890_RS13340	COG2948	multi-organism process
AB890_RS13360	COG3505	Type IV secretory pathway VirD4
AB890_RS13375	COG0556	nucleotide-excision repair
AB890_RS13430	COG4695	Portal protein
AB890_RS13475	COG3179	chitinase
AB890_RS13570	COG3275	phosphorelay sensor kinase activity
AB890_RS13575	COG1611	Belongs to the LOG family
AB890_RS13585	COG2095	MarC family integral membrane protein
AB890_RS13595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AB890_RS13630	COG1185	polyribonucleotide nucleotidyltransferase activity
AB890_RS13635	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AB890_RS13640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AB890_RS13645	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AB890_RS13650	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AB890_RS13655	COG0195	Participates in both transcription termination and antitermination
AB890_RS13660	COG0779	Required for maturation of 30S ribosomal subunits
AB890_RS13670	COG1007	ATP synthesis coupled electron transport
AB890_RS13695	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB890_RS13700	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AB890_RS13710	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AB890_RS13715	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AB890_RS13720	COG0649	NAD binding
AB890_RS13725	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB890_RS13730	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB890_RS13735	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB890_RS13750	COG0149	triose-phosphate isomerase activity
AB890_RS13755	COG0300	oxidoreductase activity
AB890_RS13790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AB890_RS13795	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AB890_RS13800	COG0159	tryptophan synthase activity
AB890_RS13810	COG0133	tryptophan synthase activity
AB890_RS13820	COG0135	phosphoribosylanthranilate isomerase activity
AB890_RS13825	COG0101	tRNA pseudouridine synthase activity
AB890_RS13850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AB890_RS13855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AB890_RS13860	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AB890_RS13865	COG2890	protein-(glutamine-N5) methyltransferase activity
AB890_RS13875	COG0688	phosphatidylethanolamine metabolic process
AB890_RS13885	COG0433	COG0433 Predicted ATPase
AB890_RS13890	COG0494	nUDIX hydrolase
AB890_RS13905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AB890_RS13910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AB890_RS13935	COG0717	Belongs to the dCTP deaminase family
AB890_RS13940	COG0489	protein tyrosine kinase activity
AB890_RS13960	COG3590	peptidase
AB890_RS13965	COG3590	peptidase
AB890_RS13985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AB890_RS13990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB890_RS13995	COG2311	Membrane
AB890_RS14000	COG1047	Peptidyl-prolyl cis-trans
AB890_RS14005	COG0791	NLP P60 protein
AB890_RS14010	COG0791	NLP P60 protein
AB890_RS14020	COG4106	trans-aconitate 2-methyltransferase activity
AB890_RS14025	COG1301	dicarboxylic acid transport
AB890_RS14030	COG1785	Belongs to the alkaline phosphatase family
AB890_RS14035	COG0037	tRNA processing
AB890_RS14040	COG1722	exodeoxyribonuclease VII activity
AB890_RS14045	COG0142	geranyltranstransferase activity
AB890_RS14050	COG4104	PAAR repeat-containing protein
AB890_RS14060	COG0312	modulator of DNA gyrase
AB890_RS14065	COG3028	Belongs to the UPF0307 family
AB890_RS14070	COG0312	modulator of DNA gyrase
AB890_RS14080	COG3164	Protein of unknown function
AB890_RS14090	COG0424	maF-like protein
AB890_RS14095	COG2968	Membrane
AB890_RS14110	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AB890_RS14125	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AB890_RS14140	COG0495	leucyl-tRNA aminoacylation
AB890_RS14150	COG3118	belongs to the thioredoxin family
AB890_RS14175	COG2155	Conserved Protein
AB890_RS14220	COG1132	(ABC) transporter
AB890_RS14250	COG1538	Outer membrane efflux protein
AB890_RS14255	COG0745	RESPONSE REGULATOR receiver
AB890_RS14260	COG5000	phosphorelay sensor kinase activity
AB890_RS14260	COG5002	protein histidine kinase activity
AB890_RS14265	COG0475	glutathione-regulated potassium exporter activity
AB890_RS14275	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AB890_RS14300	COG1187	pseudouridine synthase activity
AB890_RS14305	COG5002	protein histidine kinase activity
AB890_RS14305	COG5001	Diguanylate cyclase
AB890_RS14425	COG0667	Aldo Keto reductase
AB890_RS14430	COG2814	Major facilitator Superfamily
AB890_RS14435	COG0583	DNA-binding transcription factor activity
AB890_RS14445	COG2207	Transcriptional regulator
AB890_RS14455	COG1309	transcriptional regulator
AB890_RS14480	COG0735	belongs to the Fur family
AB890_RS14485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AB890_RS14510	COG4452	Inner membrane protein CreD
AB890_RS14520	COG2205	protein histidine kinase activity
AB890_RS14525	COG0745	RESPONSE REGULATOR receiver
AB890_RS14530	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AB890_RS14540	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AB890_RS14575	COG2198	Histidine kinase
AB890_RS14575	COG0643	Histidine kinase
AB890_RS14580	COG0840	transmembrane signaling receptor activity
AB890_RS14585	COG0835	chemotaxis
AB890_RS14590	COG2202	Pas domain
AB890_RS14590	COG2200	EAL domain
AB890_RS14590	COG2199	diguanylate cyclase activity
AB890_RS14595	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AB890_RS14600	COG2201	protein-glutamate methylesterase activity
AB890_RS14605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB890_RS14610	COG3590	peptidase
AB890_RS14620	COG0588	phosphoglycerate mutase activity
AB890_RS14625	COG1515	deoxyribonuclease V activity
AB890_RS14635	COG1741	Belongs to the pirin family
AB890_RS14650	COG1741	Belongs to the pirin family
AB890_RS14655	COG1966	Carbon starvation protein
AB890_RS14660	COG2879	small protein
AB890_RS14715	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AB890_RS14720	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AB890_RS14725	COG2080	2 iron, 2 sulfur cluster binding
AB890_RS14735	COG3706	GGDEF domain
AB890_RS14735	COG4251	negative regulation of phosphorylation
AB890_RS14735	COG5001	Diguanylate cyclase
AB890_RS14735	COG2203	Gaf domain
AB890_RS14740	COG0629	single-stranded DNA binding
AB890_RS14745	COG0142	geranyltranstransferase activity
AB890_RS14755	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AB890_RS14770	COG0527	aspartate kinase activity
AB890_RS14775	COG0384	phenazine biosynthesis protein PhzF
AB890_RS14780	COG0384	phenazine biosynthesis protein PhzF
AB890_RS14790	COG1764	response to oxidative stress
AB890_RS14795	COG0540	Belongs to the ATCase OTCase family
AB890_RS14800	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AB890_RS14805	COG1678	Uncharacterized ACR, COG1678
AB890_RS14815	COG0519	Catalyzes the synthesis of GMP from XMP
AB890_RS14825	COG5297	Belongs to the glycosyl hydrolase family 6
AB890_RS14840	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AB890_RS14855	COG0739	heme binding
AB890_RS14875	COG0693	protein deglycase activity
AB890_RS14885	COG1959	2 iron, 2 sulfur cluster binding
AB890_RS14890	COG0719	Fe-S assembly protein
AB890_RS14895	COG0396	ATPase activity
AB890_RS14900	COG0719	Fe-S assembly protein
AB890_RS14905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AB890_RS14915	COG2146	nitrite reductase [NAD(P)H] activity
AB890_RS14920	COG4774	siderophore transport
AB890_RS14925	COG3128	pkhd-type hydroxylase
AB890_RS14950	COG1477	protein flavinylation
AB890_RS14955	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AB890_RS14970	COG1555	photosystem II stabilization
AB890_RS14975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AB890_RS14985	COG3178	'Phosphotransferase
AB890_RS14990	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AB890_RS15000	COG0628	permease
AB890_RS15010	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AB890_RS15020	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AB890_RS15040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AB890_RS15045	COG0271	Belongs to the BolA IbaG family
AB890_RS15055	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AB890_RS15065	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AB890_RS15070	COG1137	ATPase activity
AB890_RS15085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB890_RS15090	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AB890_RS15095	COG1660	Displays ATPase and GTPase activities
AB890_RS15105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB890_RS15110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AB890_RS15115	COG2239	Acts as a magnesium transporter
AB890_RS15130	COG1294	oxidase, subunit
AB890_RS15135	COG1271	oxidase subunit
AB890_RS15145	COG1113	amino acid transport
AB890_RS15165	COG2197	response regulator
AB890_RS15170	COG0531	amino acid
AB890_RS15190	COG1234	tRNA 3'-trailer cleavage
AB890_RS15225	COG2814	Major facilitator Superfamily
AB890_RS15235	COG0754	glutathionylspermidine amidase activity
AB890_RS15260	COG1842	Phage shock protein A
AB890_RS15270	COG0259	pyridoxamine-phosphate oxidase activity
AB890_RS15275	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AB890_RS15280	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AB890_RS15290	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AB890_RS15365	COG2814	Major facilitator Superfamily
AB890_RS15385	COG0784	Response regulator, receiver
AB890_RS15385	COG2198	Histidine kinase
AB890_RS15385	COG2205	protein histidine kinase activity
AB890_RS15390	COG2353	YceI-like domain
AB890_RS15410	COG1760	l-serine dehydratase
AB890_RS15420	COG0527	aspartate kinase activity
AB890_RS15420	COG0460	homoserine dehydrogenase
AB890_RS15425	COG0626	cystathionine gamma-synthase activity
AB890_RS15430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AB890_RS15435	COG0739	heme binding
AB890_RS15440	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AB890_RS15445	COG1272	protein, Hemolysin III
AB890_RS15450	COG2982	Protein involved in outer membrane biogenesis
AB890_RS15455	COG0517	IMP dehydrogenase activity
AB890_RS15455	COG0516	GMP reductase activity
AB890_RS15460	COG0463	Glycosyl transferase, family 2
AB890_RS15465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AB890_RS15470	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AB890_RS15480	COG4771	TonB-dependent receptor
AB890_RS15490	COG1309	transcriptional regulator
AB890_RS15500	COG1960	acyl-CoA dehydrogenase activity
AB890_RS15525	COG0509	glycine decarboxylation via glycine cleavage system
AB890_RS15530	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AB890_RS15540	COG0330	HflC and HflK could
AB890_RS15545	COG1742	UPF0060 membrane protein
AB890_RS15550	COG3956	TIGRFAM MazG family protein
AB890_RS15560	COG0494	nUDIX hydrolase
AB890_RS15570	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AB890_RS15575	COG0837	glucose binding
AB890_RS15590	COG3858	chitin binding
AB890_RS15590	COG1388	LysM domain
AB890_RS15605	COG1472	Belongs to the glycosyl hydrolase 3 family
AB890_RS15620	COG0531	amino acid
AB890_RS15630	COG1486	melibiose metabolic process
AB890_RS15640	COG3537	Alpha-1,2-mannosidase
AB890_RS15675	COG3142	Participates in the control of copper homeostasis
AB890_RS15680	COG1446	asparaginase
AB890_RS15705	COG0784	Response regulator, receiver
AB890_RS15705	COG0643	Histidine kinase
AB890_RS15705	COG2198	Histidine kinase
AB890_RS15710	COG0840	transmembrane signaling receptor activity
AB890_RS15715	COG0835	chemotaxis
AB890_RS15730	COG0189	ligase activity
AB890_RS15740	COG1397	ADP-ribosylglycohydrolase
AB890_RS15750	COG1199	ATP-dependent helicase activity
AB890_RS15760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AB890_RS15765	COG1215	transferase activity, transferring glycosyl groups
AB890_RS15775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AB890_RS15780	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AB890_RS15785	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AB890_RS15790	COG0535	radical SAM domain protein
AB890_RS15795	COG0535	radical SAM domain protein
AB890_RS15810	COG0837	glucose binding
AB890_RS15825	COG1643	Atp-dependent helicase
AB890_RS15830	COG0783	Belongs to the Dps family
AB890_RS15835	COG0514	ATP-dependent DNA helicase (RecQ)
AB890_RS15870	COG0840	transmembrane signaling receptor activity
AB890_RS15890	COG3920	Histidine kinase
AB890_RS15895	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AB890_RS15905	COG0602	queuosine metabolic process
AB890_RS15915	COG2885	chlorophyll binding
AB890_RS15920	COG0823	Involved in the tonB-independent uptake of proteins
AB890_RS15930	COG0848	biopolymer transport protein
AB890_RS15940	COG0824	Thioesterase
AB890_RS15945	COG2255	four-way junction helicase activity
AB890_RS15955	COG3158	transport of potassium into the cell
AB890_RS15960	COG0632	four-way junction helicase activity
AB890_RS15965	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AB890_RS15970	COG0217	transcriptional regulatory protein
AB890_RS15985	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AB890_RS16000	COG0477	Major facilitator Superfamily
AB890_RS16040	COG0488	(ABC) transporter
AB890_RS16075	COG4651	solute:proton antiporter activity
AB890_RS16075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AB890_RS16100	COG4772	TonB-dependent receptor
AB890_RS16110	COG4264	IucA IucC family
AB890_RS16125	COG0019	diaminopimelate decarboxylase activity
AB890_RS16150	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AB890_RS16160	COG1492	cobalamin metabolic process
AB890_RS16170	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AB890_RS16190	COG4206	TonB-dependent receptor
AB890_RS16195	COG0542	response to heat
AB890_RS16200	COG1116	anion transmembrane transporter activity
AB890_RS16205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB890_RS16210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB890_RS16215	COG0667	Aldo Keto reductase
AB890_RS16220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB890_RS16225	COG4771	TonB-dependent receptor
AB890_RS16230	COG2827	Endonuclease containing a URI domain
AB890_RS16270	COG1877	trehalose-phosphatase activity
AB890_RS16275	COG3387	PFAM Glycoside hydrolase 15-related
AB890_RS16290	COG0840	transmembrane signaling receptor activity
AB890_RS16295	COG3011	Protein conserved in bacteria
AB890_RS16310	COG0564	pseudouridine synthase activity
AB890_RS16315	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AB890_RS16325	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AB890_RS16325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AB890_RS16345	COG2951	lytic endotransglycosylase activity
AB890_RS16350	COG4644	lycopene metabolic process
AB890_RS16365	COG2369	cell adhesion
AB890_RS16390	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AB890_RS16395	COG0045	succinate-CoA ligase (ADP-forming) activity
AB890_RS16410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AB890_RS16440	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AB890_RS16445	COG0237	dephospho-CoA kinase activity
AB890_RS16470	COG5002	protein histidine kinase activity
AB890_RS16475	COG0745	RESPONSE REGULATOR receiver
AB890_RS16545	COG2003	Belongs to the UPF0758 family
AB890_RS16570	COG0784	Response regulator, receiver
AB890_RS16570	COG4191	Histidine kinase
AB890_RS16575	COG0784	Response regulator, receiver
AB890_RS16575	COG4191	Histidine kinase
AB890_RS16685	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AB890_RS16710	COG2022	thiamine diphosphate biosynthetic process
AB890_RS16715	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AB890_RS16720	COG0471	metal ion transport
AB890_RS16720	COG3273	potassium ion transport
AB890_RS16740	COG1970	mechanosensitive ion channel activity
AB890_RS16765	COG3250	beta-galactosidase activity
AB890_RS16770	COG4948	Mandelate Racemase Muconate Lactonizing
AB890_RS16785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB890_RS16795	COG0308	aminopeptidase N
AB890_RS16835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB890_RS16845	COG2895	sulfate adenylyltransferase (ATP) activity
AB890_RS16845	COG0529	Catalyzes the synthesis of activated sulfate
AB890_RS16850	COG0175	sulfate reduction
AB890_RS16855	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AB890_RS16860	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AB890_RS16865	COG0175	sulfate reduction
AB890_RS16885	COG2198	Histidine kinase
AB890_RS16885	COG0784	Response regulator, receiver
AB890_RS16885	COG2205	protein histidine kinase activity
AB890_RS16905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AB890_RS16905	COG1648	precorrin-2 dehydrogenase activity
AB890_RS16920	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AB890_RS16925	COG3588	fructose-bisphosphate aldolase
AB890_RS16930	COG0469	pyruvate kinase activity
AB890_RS16940	COG0126	phosphoglycerate kinase activity
AB890_RS16960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AB890_RS16970	COG3047	cAMP biosynthetic process
AB890_RS16975	COG3047	cAMP biosynthetic process
AB890_RS16985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB890_RS16985	COG3453	Protein conserved in bacteria
AB890_RS16990	COG0725	ABC transporter, periplasmic molybdate-binding protein
AB890_RS16995	COG4149	molybdate abc transporter
AB890_RS17000	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AB890_RS17035	COG1376	ErfK ybiS ycfS ynhG family protein
AB890_RS17040	COG0739	heme binding
AB890_RS17050	COG4773	Receptor
AB890_RS17065	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AB890_RS17070	COG1301	dicarboxylic acid transport
AB890_RS17080	COG2304	oxidoreductase activity
AB890_RS17100	COG0714	Associated with various cellular activities
AB890_RS17130	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AB890_RS17155	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AB890_RS17165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AB890_RS17175	COG0194	GDP metabolic process
AB890_RS17180	COG1561	YicC-like family, N-terminal region
AB890_RS17185	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AB890_RS17195	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AB890_RS17200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AB890_RS17215	COG0006	proline dipeptidase activity
AB890_RS17225	COG0006	proline dipeptidase activity
AB890_RS17230	COG3079	Belongs to the UPF0149 family
AB890_RS17250	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AB890_RS17260	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AB890_RS17270	COG2912	Transglutaminase-like superfamily
AB890_RS17275	COG1773	rubredoxin
AB890_RS17280	COG0352	thiamine-phosphate diphosphorylase activity
AB890_RS17295	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AB890_RS17310	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AB890_RS17340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AB890_RS17345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AB890_RS17355	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS17365	COG0671	phosphoesterase, PA-phosphatase related
AB890_RS17370	COG3781	membrane
AB890_RS17380	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AB890_RS17385	COG0563	adenylate kinase activity
AB890_RS17400	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AB890_RS17410	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AB890_RS17430	COG3710	Transcriptional regulator
AB890_RS17435	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AB890_RS17445	COG0840	transmembrane signaling receptor activity
AB890_RS17450	COG0405	Gamma-glutamyltransferase
AB890_RS17455	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AB890_RS17475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AB890_RS17480	COG0473	3-isopropylmalate dehydrogenase activity
AB890_RS17485	COG0066	3-isopropylmalate dehydratase activity
AB890_RS17490	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AB890_RS17510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AB890_RS17515	COG1538	Outer membrane efflux protein
AB890_RS17520	COG1519	Transferase
AB890_RS17525	COG1560	Kdo2-lipid A biosynthetic process
AB890_RS17550	COG0281	malic enzyme
AB890_RS17550	COG0280	phosphate acetyltransferase
AB890_RS17555	COG1301	dicarboxylic acid transport
AB890_RS17580	COG0583	DNA-binding transcription factor activity
AB890_RS17585	COG0667	Aldo Keto reductase
AB890_RS17600	COG2197	response regulator
AB890_RS17610	COG0642	Histidine kinase
AB890_RS17625	COG2851	Citrate transporter
AB890_RS17630	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS17635	COG1609	Transcriptional regulator
AB890_RS17640	COG2211	Major facilitator Superfamily
AB890_RS17665	COG1162	GTPase activity
AB890_RS17685	COG4773	Receptor
AB890_RS17690	COG0726	polysaccharide deacetylase
AB890_RS17695	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AB890_RS17730	COG1307	EDD domain protein, DegV family
AB890_RS17735	COG0242	peptide deformylase activity
AB890_RS17755	COG0457	Tetratricopeptide repeat
AB890_RS17760	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AB890_RS17765	COG1215	transferase activity, transferring glycosyl groups
AB890_RS17770	COG1215	transferase activity, transferring glycosyl groups
AB890_RS17785	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AB890_RS17840	COG2188	Transcriptional regulator
AB890_RS17850	COG1450	Type ii and iii secretion system protein
AB890_RS17865	COG3166	PFAM Fimbrial assembly family protein
AB890_RS17870	COG3156	type II secretion system protein K
AB890_RS17875	COG4795	General secretion pathway protein
AB890_RS17880	COG2165	general secretion pathway protein
AB890_RS17885	COG4970	Tfp pilus assembly protein FimT
AB890_RS17890	COG2165	general secretion pathway protein
AB890_RS17895	COG1459	type II secretion system
AB890_RS17900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AB890_RS17905	COG1404	Belongs to the peptidase S8 family
AB890_RS17910	COG5295	Hep Hag repeat protein
AB890_RS17915	COG1404	Belongs to the peptidase S8 family
AB890_RS17920	COG5295	Hep Hag repeat protein
AB890_RS17930	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AB890_RS17930	COG0047	phosphoribosylformylglycinamidine synthase activity
AB890_RS17935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AB890_RS17940	COG4974	Belongs to the 'phage' integrase family
AB890_RS17955	COG0795	lipopolysaccharide-transporting ATPase activity
AB890_RS17965	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AB890_RS17980	COG0525	valine-tRNA ligase activity
AB890_RS18010	COG1183	phosphatidylcholine synthase activity
AB890_RS18020	COG0442	prolyl-tRNA aminoacylation
AB890_RS18035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AB890_RS18040	COG1127	ABC transporter
AB890_RS18045	COG3218	ABC-type transport auxiliary lipoprotein component
AB890_RS18045	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB890_RS18080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AB890_RS18085	COG0662	Cupin 2, conserved barrel domain protein
AB890_RS18085	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AB890_RS18115	COG2086	electron transfer activity
AB890_RS18130	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AB890_RS18130	COG0546	phosphoglycolate phosphatase activity
AB890_RS18135	COG0277	FAD linked oxidase domain protein
AB890_RS18150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB890_RS18180	COG1216	Glycosyl transferase, family 2
AB890_RS18180	COG0438	transferase activity, transferring glycosyl groups
AB890_RS18200	COG0626	cystathionine gamma-synthase activity
AB890_RS18235	COG0625	glutathione transferase activity
AB890_RS18245	COG0513	Belongs to the DEAD box helicase family
AB890_RS18260	COG4206	TonB-dependent receptor
AB890_RS18265	COG0720	synthase
AB890_RS18275	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AB890_RS18285	COG1956	GAF domain-containing protein
AB890_RS18295	COG2819	hydrolase of the alpha beta superfamily
AB890_RS18310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AB890_RS18315	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AB890_RS18330	COG0339	signal peptide processing
AB890_RS18385	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AB890_RS18390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB890_RS18395	COG4591	ABC-type transport system involved in lipoprotein release permease component
AB890_RS18395	COG1136	(ABC) transporter
AB890_RS18400	COG1136	(ABC) transporter
AB890_RS18400	COG0577	efflux transmembrane transporter activity
AB890_RS18405	COG0577	efflux transmembrane transporter activity
AB890_RS18420	COG4191	Histidine kinase
AB890_RS18425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AB890_RS18440	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AB890_RS18445	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AB890_RS18450	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AB890_RS18455	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AB890_RS18460	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AB890_RS18465	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AB890_RS18475	COG0356	it plays a direct role in the translocation of protons across the membrane
AB890_RS18495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AB890_RS18505	COG0508	dehydrogenase complex catalyzes the overall conversion of
AB890_RS18550	COG2011	ABC-type metal ion transport system permease component
AB890_RS18555	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AB890_RS18560	COG0697	spore germination
AB890_RS18565	COG1666	GTP binding
AB890_RS18575	COG0784	Response regulator, receiver
AB890_RS18575	COG2198	Histidine kinase
AB890_RS18575	COG5002	protein histidine kinase activity
AB890_RS18600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AB890_RS18605	COG1187	pseudouridine synthase activity
AB890_RS18610	COG2813	Specifically methylates the guanine in position
AB890_RS18630	COG2202	Pas domain
AB890_RS18630	COG2205	protein histidine kinase activity
AB890_RS18650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AB890_RS18655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB890_RS18710	COG0842	Transport permease protein
AB890_RS18715	COG1131	(ABC) transporter
AB890_RS18720	COG0025	NhaP-type Na H and K H
AB890_RS18725	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AB890_RS18730	COG1573	uracil-dna glycosylase
AB890_RS18740	COG3384	dioxygenase
AB890_RS18750	COG0583	DNA-binding transcription factor activity
AB890_RS18760	COG0667	Aldo Keto reductase
AB890_RS18790	COG0531	amino acid
AB890_RS18820	COG3685	Protein conserved in bacteria
AB890_RS18825	COG3546	catalase activity
AB890_RS18870	COG1271	oxidase subunit
AB890_RS18875	COG1294	oxidase, subunit
AB890_RS18890	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS18895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AB890_RS18915	COG1132	(ABC) transporter
AB890_RS18930	COG1063	alcohol dehydrogenase
AB890_RS19005	COG0251	oxidation-reduction process
AB890_RS19035	COG0840	transmembrane signaling receptor activity
AB890_RS19055	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AB890_RS19095	COG0024	Methionine aminopeptidase
AB890_RS19115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AB890_RS19120	COG1490	D-aminoacyl-tRNA deacylase activity
AB890_RS19125	COG1560	Kdo2-lipid A biosynthetic process
AB890_RS19180	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AB890_RS19180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AB890_RS19185	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AB890_RS19190	COG0242	peptide deformylase activity
AB890_RS19195	COG1652	LysM domain
AB890_RS19200	COG0758	DNA mediated transformation
AB890_RS19205	COG2922	Belongs to the Smg family
AB890_RS19220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AB890_RS19220	COG1754	DNA topoisomerase type I activity
AB890_RS19225	COG0009	L-threonylcarbamoyladenylate synthase
AB890_RS19240	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS19250	COG0616	signal peptide processing
AB890_RS19255	COG0534	Mate efflux family protein
AB890_RS19275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AB890_RS19280	COG0625	glutathione transferase activity
AB890_RS19295	COG1252	NADH dehydrogenase
AB890_RS19300	COG2860	membrane
AB890_RS19305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AB890_RS19310	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AB890_RS19315	COG3437	response regulator, receiver
AB890_RS19320	COG2177	Part of the ABC transporter FtsEX involved in
AB890_RS19325	COG2884	Cell division ATP-binding protein ftsE
AB890_RS19330	COG0513	Belongs to the DEAD box helicase family
AB890_RS19335	COG3118	belongs to the thioredoxin family
AB890_RS19340	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AB890_RS19345	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AB890_RS19350	COG0583	DNA-binding transcription factor activity
AB890_RS19395	COG1518	maintenance of DNA repeat elements
AB890_RS19400	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AB890_RS19410	COG1652	LysM domain
AB890_RS19415	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AB890_RS19415	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AB890_RS19420	COG1473	amidohydrolase
AB890_RS19425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB890_RS19430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB890_RS19440	COG5383	Protein conserved in bacteria
AB890_RS19480	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AB890_RS19485	COG3023	N-Acetylmuramoyl-L-alanine amidase
AB890_RS19495	COG4948	Mandelate Racemase Muconate Lactonizing
AB890_RS19505	COG0531	amino acid
AB890_RS19520	COG4682	membrane
AB890_RS19525	COG2133	pyrroloquinoline quinone binding
AB890_RS19535	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AB890_RS19540	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AB890_RS19550	COG1610	YqeY-like protein
AB890_RS19555	COG1295	ribonuclease BN
AB890_RS19560	COG0358	DNA primase activity
AB890_RS19575	COG0109	protoheme IX farnesyltransferase activity
AB890_RS19605	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AB890_RS19615	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AB890_RS19660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AB890_RS19665	COG0739	heme binding
AB890_RS19670	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AB890_RS19680	COG2211	Major facilitator Superfamily
AB890_RS19685	COG0708	Exodeoxyribonuclease III
AB890_RS19690	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AB890_RS19700	COG1192	Involved in chromosome partitioning
AB890_RS19705	COG1475	DNA binding
AB890_RS19720	COG0463	Glycosyl transferase, family 2
AB890_RS19740	COG0756	dUTP diphosphatase activity
AB890_RS19745	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AB890_RS19750	COG2003	Belongs to the UPF0758 family
AB890_RS19755	COG0018	arginyl-trna synthetase
AB890_RS19770	COG4221	oxidoreductase activity
AB890_RS19775	COG2755	lipolytic protein G-D-S-L family
AB890_RS19775	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AB890_RS19785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AB890_RS19795	COG1166	arginine decarboxylase activity
AB890_RS19800	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AB890_RS19840	COG0606	chelatase, subunit chli
AB890_RS19855	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AB890_RS19890	COG1690	Belongs to the RtcB family
AB890_RS19930	COG1090	epimerase
AB890_RS19940	COG0642	Histidine kinase
AB890_RS19965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB890_RS19990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AB890_RS19995	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AB890_RS20010	COG0753	catalase activity
AB890_RS20025	COG2197	response regulator
AB890_RS20030	COG4585	Histidine kinase
AB890_RS20035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB890_RS20040	COG1136	(ABC) transporter
AB890_RS20065	COG0697	spore germination
AB890_RS20080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB890_RS20085	COG0180	Tryptophanyl-tRNA synthetase
AB890_RS20090	COG3237	CsbD-like
AB890_RS20130	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AB890_RS20145	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AB890_RS20190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AB890_RS20210	COG1199	ATP-dependent helicase activity
AB890_RS20225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AB890_RS20290	COG0625	glutathione transferase activity
AB890_RS20330	COG4555	ABC transporter
AB890_RS20340	COG1476	TRANSCRIPTIONal
AB890_RS20385	COG0633	Ferredoxin
AB890_RS20385	COG0543	2 iron, 2 sulfur cluster binding
AB890_RS20390	COG1131	(ABC) transporter
AB890_RS20395	COG0842	Transport permease protein
AB890_RS20405	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AB890_RS20440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AB890_RS20445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AB890_RS20455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AB890_RS20455	COG1042	CoA-binding domain protein
AB890_RS20455	COG0045	succinate-CoA ligase (ADP-forming) activity
AB890_RS20460	COG2239	Acts as a magnesium transporter
AB890_RS20475	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AB890_RS20480	COG3387	PFAM Glycoside hydrolase 15-related
AB890_RS20495	COG3100	YcgL domain-containing protein
AB890_RS20500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AB890_RS20510	COG0463	Glycosyl transferase, family 2
AB890_RS20530	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS20570	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AB890_RS20585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AB890_RS20610	COG4946	Tricorn protease homolog
AB890_RS20610	COG1506	peptidase
AB890_RS20610	COG0823	Involved in the tonB-independent uptake of proteins
AB890_RS20625	COG0408	coproporphyrinogen oxidase activity
AB890_RS20660	COG0515	serine threonine protein kinase
AB890_RS20660	COG2815	serine threonine protein kinase
AB890_RS20665	COG0631	protein serine/threonine phosphatase activity
AB890_RS20825	COG0210	DNA helicase
AB890_RS20840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB890_RS20845	COG0583	DNA-binding transcription factor activity
AB890_RS20850	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AB890_RS20860	COG2159	amidohydrolase
AB890_RS20880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB890_RS20900	COG0357	Ribosomal RNA small subunit methyltransferase G
AB890_RS20905	COG3540	Alkaline phosphatase
AB890_RS20915	COG2091	lysine biosynthetic process via aminoadipic acid
AB890_RS20935	COG0708	Exodeoxyribonuclease III
AB890_RS20940	COG1846	Transcriptional regulator
AB890_RS20940	COG1940	carbohydrate kinase activity
AB890_RS20950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AB890_RS20960	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AB890_RS20965	COG3162	membrane
AB890_RS20975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB890_RS21005	COG3507	Belongs to the glycosyl hydrolase 43 family
AB890_RS21025	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_RS21030	COG0179	Fumarylacetoacetate (FAA) hydrolase
AB890_RS21035	COG4948	Mandelate Racemase Muconate Lactonizing
AB890_RS21045	COG3254	rhamnose metabolic process
AB890_RS21050	COG0738	Major facilitator superfamily
AB890_RS21055	COG1414	Transcriptional regulator
AB890_RS21060	COG1971	Probably functions as a manganese efflux pump
AB890_RS21065	COG2205	protein histidine kinase activity
AB890_RS21080	COG3459	Glycosyltransferase 36 associated
AB890_RS21085	COG2211	Major facilitator Superfamily
AB890_RS21090	COG3265	gluconokinase activity
AB890_RS21095	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AB890_RS21115	COG2911	Protein conserved in bacteria
AB890_RS21120	COG0729	surface antigen
AB890_RS21150	COG0752	glycyl-tRNA synthetase alpha subunit
AB890_RS21155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AB890_RS21165	COG0519	Catalyzes the synthesis of GMP from XMP
AB890_RS21165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AB890_RS21175	COG0805	protein transport
AB890_RS21180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AB890_RS21185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AB890_RS21195	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AB890_RS21215	COG2974	May be involved in recombination
AB890_RS21220	COG0037	tRNA processing
AB890_RS21225	COG2115	Belongs to the xylose isomerase family
AB890_RS21235	COG3661	Belongs to the glycosyl hydrolase 67 family
AB890_RS21245	COG4948	Mandelate Racemase Muconate Lactonizing
AB890_RS21255	COG1472	Belongs to the glycosyl hydrolase 3 family
AB890_RS21260	COG0246	Mannitol dehydrogenase
AB890_RS21335	COG3386	PFAM SMP-30 Gluconolaconase
AB890_RS21345	COG3250	beta-galactosidase activity
AB890_RS21350	COG1904	glucuronate isomerase
AB890_RS21370	COG3693	PFAM glycoside hydrolase, family 10
AB890_RS21385	COG2211	Major facilitator Superfamily
AB890_RS21430	COG2937	Belongs to the GPAT DAPAT family
AB890_RS21465	COG0284	orotidine-5'-phosphate decarboxylase activity
AB890_RS21470	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AB890_RS21475	COG3132	Protein of unknown function, DUF480
AB890_RS21490	COG0210	DNA helicase
AB890_RS21495	COG1435	thymidine kinase activity
AB890_RS21505	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AB890_RS21515	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AB890_RS21550	COG3135	benzoate transporter
AB890_RS21570	COG0676	glucose-6-phosphate 1-epimerase activity
AB890_RS21580	COG3012	SEC-C Motif Domain Protein
AB890_RS21585	COG0730	response to heat
AB890_RS21605	COG0302	gtp cyclohydrolase
AB890_RS21620	COG1566	PFAM secretion protein HlyD family protein
AB890_RS21630	COG1289	transmembrane transporter activity
AB890_RS21635	COG0477	Major facilitator Superfamily
AB890_RS21645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB890_RS21665	COG4691	Plasmid stability protein
AB890_RS21670	COG1487	ribonuclease activity
AB890_RS21695	COG0564	pseudouridine synthase activity
AB890_RS21720	COG0439	Biotin carboxylase
AB890_RS21755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AB890_RS21760	COG1074	ATP-dependent DNA helicase activity
AB890_RS21765	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AB890_RS21780	COG1127	ABC transporter
AB890_RS21785	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AB890_RS21790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB890_RS21815	COG0386	Belongs to the glutathione peroxidase family
AB890_RS21825	COG1322	Protein conserved in bacteria
AB890_RS21830	COG0604	alcohol dehydrogenase
AB890_RS21845	COG0625	glutathione transferase activity
AB890_RS21855	COG0531	amino acid
AB890_RS21860	COG3537	Alpha-1,2-mannosidase
AB890_RS21870	COG3706	GGDEF domain
AB890_RS21875	COG3835	regulator
AB890_RS21880	COG1929	Belongs to the glycerate kinase type-1 family
AB890_RS21885	COG2271	Major facilitator Superfamily
AB890_RS21900	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AB890_RS21905	COG0861	Integral membrane protein TerC family
AB890_RS21915	COG0584	glycerophosphoryl diester phosphodiesterase
AB890_RS21930	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AB890_RS21935	COG0726	polysaccharide deacetylase
AB890_RS21945	COG0706	membrane insertase activity
AB890_RS21950	COG0594	ribonuclease P activity
AB890_RS21985	COG2951	lytic endotransglycosylase activity
AB890_RS21990	COG4644	lycopene metabolic process
AB890_RS22120	COG2948	multi-organism process
AB890_RS22125	COG3504	Conjugal transfer protein
AB890_RS22230	COG4456	Virulence-associated protein
AB890_RS22235	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AB890_RS22240	COG2801	Transposase and inactivated derivatives
AB890_RS22265	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AB890_RS22425	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AB890_RS22445	COG1192	Involved in chromosome partitioning
AB890_RS22855	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AB890_RS22990	COG1960	acyl-CoA dehydrogenase activity
AB890_RS22995	COG1960	acyl-CoA dehydrogenase activity
AB890_RS23000	COG1960	acyl-CoA dehydrogenase activity
AB890_RS23145	COG3002	Belongs to the UPF0753 family
AB890_RS23200	COG0582	viral genome integration into host DNA
AB890_RS23740	COG0596	Alpha beta hydrolase
AB890_RS23890	COG2972	Histidine kinase
AB890_RS24285	COG3012	SEC-C Motif Domain Protein
AB890_RS24285	COG3318	Belongs to the UPF0149 family
AB890_RS24300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AB890_RS24335	COG3012	SEC-C Motif Domain Protein
AB890_RS24335	COG3318	Belongs to the UPF0149 family