locus-tag	class	description
EBN15_RS00020	COG0187	DNA topoisomerase II activity
EBN15_RS00030	COG0501	Belongs to the peptidase M48B family
EBN15_RS00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EBN15_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBN15_RS00105	COG0793	Belongs to the peptidase S41A family
EBN15_RS00110	COG4942	peptidase
EBN15_RS00120	COG2234	aminopeptidase activity
EBN15_RS00125	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBN15_RS00130	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBN15_RS00135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBN15_RS00140	COG1064	alcohol dehydrogenase
EBN15_RS00145	COG0493	'glutamate synthase
EBN15_RS00150	COG0067	glutamate synthase
EBN15_RS00150	COG0070	glutamate synthase
EBN15_RS00150	COG0069	glutamate synthase activity
EBN15_RS00250	COG0302	gtp cyclohydrolase
EBN15_RS00270	COG0730	response to heat
EBN15_RS00275	COG3012	SEC-C Motif Domain Protein
EBN15_RS00285	COG1322	Protein conserved in bacteria
EBN15_RS00290	COG0386	Belongs to the glutathione peroxidase family
EBN15_RS00295	COG2853	Lipoprotein
EBN15_RS00310	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBN15_RS00315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBN15_RS00320	COG1127	ABC transporter
EBN15_RS00355	COG3631	Ketosteroid isomerase-related protein
EBN15_RS00380	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EBN15_RS00385	COG1074	ATP-dependent DNA helicase activity
EBN15_RS00395	COG3549	Plasmid maintenance system killer
EBN15_RS00495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBN15_RS00505	COG0477	Major facilitator Superfamily
EBN15_RS00535	COG1111	helicase
EBN15_RS00535	COG1205	dead DEAH box helicase
EBN15_RS00540	COG1272	protein, Hemolysin III
EBN15_RS00575	COG3265	gluconokinase activity
EBN15_RS00580	COG2211	Major facilitator Superfamily
EBN15_RS00585	COG3459	Glycosyltransferase 36 associated
EBN15_RS00590	COG0784	Response regulator, receiver
EBN15_RS00590	COG2205	protein histidine kinase activity
EBN15_RS00595	COG1971	Probably functions as a manganese efflux pump
EBN15_RS00600	COG1414	Transcriptional regulator
EBN15_RS00605	COG0738	Major facilitator superfamily
EBN15_RS00610	COG3254	rhamnose metabolic process
EBN15_RS00615	COG4948	Mandelate Racemase Muconate Lactonizing
EBN15_RS00620	COG0179	Fumarylacetoacetate (FAA) hydrolase
EBN15_RS00625	COG1028	Short-chain dehydrogenase reductase Sdr
EBN15_RS00665	COG3162	membrane
EBN15_RS00680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EBN15_RS00690	COG1940	carbohydrate kinase activity
EBN15_RS00705	COG0708	Exodeoxyribonuclease III
EBN15_RS00720	COG2091	lysine biosynthetic process via aminoadipic acid
EBN15_RS00725	COG3540	Alkaline phosphatase
EBN15_RS00730	COG0357	Ribosomal RNA small subunit methyltransferase G
EBN15_RS00740	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EBN15_RS00745	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EBN15_RS00750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBN15_RS00760	COG0210	DNA helicase
EBN15_RS00835	COG3590	peptidase
EBN15_RS00875	COG0477	Major facilitator Superfamily
EBN15_RS00915	COG0714	Associated with various cellular activities
EBN15_RS00940	COG4733	cellulase activity
EBN15_RS00960	COG3039	Transposase
EBN15_RS00985	COG4772	TonB-dependent receptor
EBN15_RS01015	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EBN15_RS01085	COG2197	response regulator
EBN15_RS01095	COG3039	Transposase
EBN15_RS01100	COG4585	Histidine kinase
EBN15_RS01130	COG3501	Rhs element vgr protein
EBN15_RS01170	COG0631	protein serine/threonine phosphatase activity
EBN15_RS01210	COG0408	coproporphyrinogen oxidase activity
EBN15_RS01245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBN15_RS01260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBN15_RS01285	COG1028	Short-chain dehydrogenase reductase Sdr
EBN15_RS01300	COG0463	Glycosyl transferase, family 2
EBN15_RS01310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EBN15_RS01315	COG3100	YcgL domain-containing protein
EBN15_RS01335	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBN15_RS01375	COG0583	DNA-binding transcription factor activity
EBN15_RS01380	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EBN15_RS01385	COG2224	Isocitrate lyase
EBN15_RS01390	COG3706	GGDEF domain
EBN15_RS01430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EBN15_RS01435	COG1960	acyl-CoA dehydrogenase activity
EBN15_RS01495	COG0697	spore germination
EBN15_RS01505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EBN15_RS01520	COG1846	Transcriptional regulator
EBN15_RS01525	COG1764	response to oxidative stress
EBN15_RS01535	COG2130	NADP-dependent
EBN15_RS01540	COG0667	Aldo Keto reductase
EBN15_RS01550	COG1187	pseudouridine synthase activity
EBN15_RS01560	COG1643	Atp-dependent helicase
EBN15_RS01565	COG0840	transmembrane signaling receptor activity
EBN15_RS01570	COG4807	Protein conserved in bacteria
EBN15_RS01585	COG0084	hydrolase, TatD family'
EBN15_RS01600	COG1902	pentaerythritol trinitrate reductase activity
EBN15_RS01615	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EBN15_RS01620	COG0583	DNA-binding transcription factor activity
EBN15_RS01635	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EBN15_RS01645	COG0702	epimerase
EBN15_RS01650	COG1733	regulation of RNA biosynthetic process
EBN15_RS01655	COG1999	signal sequence binding
EBN15_RS01665	COG4774	siderophore transport
EBN15_RS01670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBN15_RS01695	COG0129	dihydroxy-acid dehydratase activity
EBN15_RS01700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EBN15_RS01705	COG2814	Major facilitator Superfamily
EBN15_RS01780	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EBN15_RS01785	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EBN15_RS01815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EBN15_RS01820	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EBN15_RS01830	COG3485	protocatechuate 3,4-dioxygenase
EBN15_RS01835	COG3485	protocatechuate 3,4-dioxygenase
EBN15_RS01845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBN15_RS01850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EBN15_RS01855	COG1414	Transcriptional regulator
EBN15_RS01870	COG0445	tRNA wobble uridine modification
EBN15_RS01915	COG0156	8-amino-7-oxononanoate synthase activity
EBN15_RS01920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EBN15_RS01925	COG1040	competence protein
EBN15_RS01930	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EBN15_RS01965	COG1511	domain protein
EBN15_RS01965	COG3264	Mechanosensitive ion channel
EBN15_RS01985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBN15_RS01995	COG0745	RESPONSE REGULATOR receiver
EBN15_RS01995	COG3706	GGDEF domain
EBN15_RS02000	COG0297	glycogen (starch) synthase activity
EBN15_RS02005	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EBN15_RS02010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EBN15_RS02035	COG0702	epimerase
EBN15_RS02040	COG1028	Short-chain dehydrogenase reductase Sdr
EBN15_RS02060	COG0513	Belongs to the DEAD box helicase family
EBN15_RS02075	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBN15_RS02090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EBN15_RS02125	COG2852	Protein conserved in bacteria
EBN15_RS02135	COG1320	monovalent cation:proton antiporter activity
EBN15_RS02140	COG2212	antiporter activity
EBN15_RS02150	COG0651	ATP synthesis coupled electron transport
EBN15_RS02155	COG1006	Multisubunit Na H antiporter MnhC subunit
EBN15_RS02160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBN15_RS02160	COG2111	Na H antiporter
EBN15_RS02185	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EBN15_RS02195	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EBN15_RS02205	COG1597	lipid kinase activity
EBN15_RS02240	COG4372	Transposase
EBN15_RS02245	COG4372	Transposase
EBN15_RS02265	COG4372	Transposase
EBN15_RS02300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EBN15_RS02305	COG0546	phosphoglycolate phosphatase activity
EBN15_RS02315	COG1956	GAF domain-containing protein
EBN15_RS02320	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EBN15_RS02330	COG0720	synthase
EBN15_RS02335	COG0513	Belongs to the DEAD box helicase family
EBN15_RS02350	COG0625	glutathione transferase activity
EBN15_RS02380	COG0626	cystathionine gamma-synthase activity
EBN15_RS02405	COG0438	transferase activity, transferring glycosyl groups
EBN15_RS02420	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EBN15_RS02435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBN15_RS02460	COG2086	electron transfer activity
EBN15_RS02485	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EBN15_RS02485	COG0662	Cupin 2, conserved barrel domain protein
EBN15_RS02525	COG3218	ABC-type transport auxiliary lipoprotein component
EBN15_RS02525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBN15_RS02530	COG1127	ABC transporter
EBN15_RS02535	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBN15_RS02550	COG0442	prolyl-tRNA aminoacylation
EBN15_RS02560	COG1183	phosphatidylcholine synthase activity
EBN15_RS02590	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBN15_RS02600	COG0795	lipopolysaccharide-transporting ATPase activity
EBN15_RS02610	COG4974	Belongs to the 'phage' integrase family
EBN15_RS02615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EBN15_RS02620	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBN15_RS02620	COG0047	phosphoribosylformylglycinamidine synthase activity
EBN15_RS02625	COG5295	Hep Hag repeat protein
EBN15_RS02630	COG1404	Belongs to the peptidase S8 family
EBN15_RS02650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBN15_RS02655	COG1459	type II secretion system
EBN15_RS02660	COG2165	general secretion pathway protein
EBN15_RS02665	COG4970	Tfp pilus assembly protein FimT
EBN15_RS02670	COG2165	general secretion pathway protein
EBN15_RS02675	COG4795	General secretion pathway protein
EBN15_RS02680	COG3156	type II secretion system protein K
EBN15_RS02685	COG3166	PFAM Fimbrial assembly family protein
EBN15_RS02700	COG1450	Type ii and iii secretion system protein
EBN15_RS02715	COG2188	Transcriptional regulator
EBN15_RS02765	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EBN15_RS02780	COG1215	transferase activity, transferring glycosyl groups
EBN15_RS02785	COG1215	transferase activity, transferring glycosyl groups
EBN15_RS02790	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EBN15_RS02795	COG0457	Tetratricopeptide repeat
EBN15_RS02800	COG1404	Belongs to the peptidase S8 family
EBN15_RS02810	COG0242	peptide deformylase activity
EBN15_RS02815	COG0488	(ABC) transporter
EBN15_RS02825	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EBN15_RS02830	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EBN15_RS02840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBN15_RS02840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBN15_RS02860	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EBN15_RS02870	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EBN15_RS02880	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EBN15_RS02885	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EBN15_RS02890	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EBN15_RS02895	COG2205	protein histidine kinase activity
EBN15_RS02900	COG0745	RESPONSE REGULATOR receiver
EBN15_RS02905	COG1408	metallophosphoesterase
EBN15_RS02910	COG0667	Aldo Keto reductase
EBN15_RS02920	COG0277	FAD linked oxidase domain protein
EBN15_RS02960	COG2001	Belongs to the MraZ family
EBN15_RS02970	COG3116	cell division
EBN15_RS02980	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EBN15_RS02985	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EBN15_RS02990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBN15_RS03000	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EBN15_RS03005	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBN15_RS03010	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBN15_RS03015	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EBN15_RS03040	COG0739	heme binding
EBN15_RS03050	COG0494	nUDIX hydrolase
EBN15_RS03060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EBN15_RS03070	COG0604	alcohol dehydrogenase
EBN15_RS03070	COG3321	synthase
EBN15_RS03070	COG1028	Short-chain dehydrogenase reductase Sdr
EBN15_RS03080	COG0366	Alpha amylase catalytic
EBN15_RS03115	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EBN15_RS03125	COG2885	chlorophyll binding
EBN15_RS03140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EBN15_RS03150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBN15_RS03160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EBN15_RS03165	COG0667	Aldo Keto reductase
EBN15_RS03175	COG4771	TonB-dependent receptor
EBN15_RS03215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EBN15_RS03220	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EBN15_RS03240	COG4181	ATPase activity
EBN15_RS03255	COG0642	Histidine kinase
EBN15_RS03265	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EBN15_RS03270	COG3604	Transcriptional regulator
EBN15_RS03275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EBN15_RS03275	COG1017	nitric oxide dioxygenase activity
EBN15_RS03295	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EBN15_RS03310	COG3829	transcription factor binding
EBN15_RS03320	COG1116	anion transmembrane transporter activity
EBN15_RS03325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EBN15_RS03335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBN15_RS03340	COG0431	NADPH-dependent FMN reductase
EBN15_RS03350	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EBN15_RS03355	COG2967	ApaG domain
EBN15_RS03360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EBN15_RS03365	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EBN15_RS03380	COG0123	including yeast histone deacetylase and acetoin utilization protein
EBN15_RS03385	COG2096	Adenosyltransferase
EBN15_RS03395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBN15_RS03400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBN15_RS03410	COG0583	DNA-binding transcription factor activity
EBN15_RS03415	COG0318	PFAM AMP-dependent synthetase and ligase
EBN15_RS03420	COG1024	Enoyl-CoA hydratase
EBN15_RS03460	COG0697	spore germination
EBN15_RS03465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EBN15_RS03470	COG3706	GGDEF domain
EBN15_RS03470	COG0745	RESPONSE REGULATOR receiver
EBN15_RS03475	COG2205	protein histidine kinase activity
EBN15_RS03475	COG5002	protein histidine kinase activity
EBN15_RS03475	COG0784	Response regulator, receiver
EBN15_RS03480	COG2197	response regulator
EBN15_RS03490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EBN15_RS03500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EBN15_RS03505	COG0583	DNA-binding transcription factor activity
EBN15_RS03510	COG3634	alkyl hydroperoxide reductase activity
EBN15_RS03520	COG2890	protein-(glutamine-N5) methyltransferase activity
EBN15_RS03555	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBN15_RS03575	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBN15_RS03580	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EBN15_RS03595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EBN15_RS03605	COG1404	Belongs to the peptidase S8 family
EBN15_RS03610	COG1404	Belongs to the peptidase S8 family
EBN15_RS03615	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EBN15_RS03635	COG1295	ribonuclease BN
EBN15_RS03640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBN15_RS03645	COG1254	Belongs to the acylphosphatase family
EBN15_RS03660	COG0521	Mo-molybdopterin cofactor biosynthetic process
EBN15_RS03670	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EBN15_RS03675	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EBN15_RS03685	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EBN15_RS03690	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EBN15_RS03700	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EBN15_RS03705	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EBN15_RS03710	COG0193	aminoacyl-tRNA hydrolase activity
EBN15_RS03715	COG0012	GTP binding
EBN15_RS03735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EBN15_RS03745	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EBN15_RS03750	COG0250	Participates in transcription elongation, termination and antitermination
EBN15_RS03755	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EBN15_RS03760	COG0081	regulation of translation
EBN15_RS03765	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EBN15_RS03770	COG0222	ribosome binding
EBN15_RS03775	COG0085	RNA polymerase activity
EBN15_RS03795	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EBN15_RS03800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EBN15_RS03805	COG0051	transcription antitermination factor activity, RNA binding
EBN15_RS03815	COG0088	Forms part of the polypeptide exit tunnel
EBN15_RS03825	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EBN15_RS03835	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EBN15_RS03840	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EBN15_RS03845	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EBN15_RS03855	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EBN15_RS03860	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EBN15_RS03865	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EBN15_RS03875	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EBN15_RS03885	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EBN15_RS03895	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EBN15_RS03900	COG1841	ribosomal large subunit assembly
EBN15_RS03905	COG0200	Binds to the 23S rRNA
EBN15_RS03910	COG0201	protein transport
EBN15_RS03915	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EBN15_RS03920	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EBN15_RS03925	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EBN15_RS03930	COG0202	RNA polymerase activity
EBN15_RS03935	COG0203	ribosomal protein L17
EBN15_RS03940	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EBN15_RS03950	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EBN15_RS03960	COG0154	amidase activity
EBN15_RS03975	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EBN15_RS03985	COG0625	glutathione transferase activity
EBN15_RS03995	COG1902	pentaerythritol trinitrate reductase activity
EBN15_RS03995	COG0446	pyridine nucleotide-disulphide oxidoreductase
EBN15_RS04000	COG0604	alcohol dehydrogenase
EBN15_RS04005	COG2885	chlorophyll binding
EBN15_RS04030	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EBN15_RS04035	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EBN15_RS04040	COG4208	sulfate ABC transporter
EBN15_RS04045	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EBN15_RS04075	COG0406	alpha-ribazole phosphatase activity
EBN15_RS04080	COG0285	dihydrofolate synthase activity
EBN15_RS04100	COG2833	Protein of unknown function (DUF455)
EBN15_RS04105	COG3291	Pkd domain containing protein
EBN15_RS04115	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBN15_RS04120	COG0671	phosphoesterase, PA-phosphatase related
EBN15_RS04125	COG0438	transferase activity, transferring glycosyl groups
EBN15_RS04135	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EBN15_RS04150	COG4783	chaperone-mediated protein folding
EBN15_RS04165	COG0473	3-isopropylmalate dehydrogenase activity
EBN15_RS04215	COG3039	Transposase
EBN15_RS04245	COG0544	peptidyl-prolyl cis-trans isomerase activity
EBN15_RS04250	COG0740	serine-type endopeptidase activity
EBN15_RS04255	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EBN15_RS04285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EBN15_RS04295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBN15_RS04305	COG0328	RNA-DNA hybrid ribonuclease activity
EBN15_RS04310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBN15_RS04315	COG0631	protein serine/threonine phosphatase activity
EBN15_RS04330	COG0859	PFAM glycosyl transferase family 9
EBN15_RS04340	COG1234	tRNA 3'-trailer cleavage
EBN15_RS04345	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EBN15_RS04355	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EBN15_RS04360	COG0314	molybdopterin synthase activity
EBN15_RS04380	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EBN15_RS04385	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EBN15_RS04390	COG0537	adenosine 5'-monophosphoramidase activity
EBN15_RS04410	COG0714	Associated with various cellular activities
EBN15_RS04425	COG1399	metal-binding, possibly nucleic acid-binding protein
EBN15_RS04430	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EBN15_RS04435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBN15_RS04445	COG1028	Short-chain dehydrogenase reductase Sdr
EBN15_RS04450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBN15_RS04460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EBN15_RS04465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EBN15_RS04525	COG4372	Transposase
EBN15_RS04550	COG3829	transcription factor binding
EBN15_RS04565	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EBN15_RS04570	COG3609	addiction module antidote protein, CC2985 family
EBN15_RS04595	COG2373	Large extracellular alpha-helical protein
EBN15_RS04615	COG0678	peroxiredoxin activity
EBN15_RS04635	COG0330	HflC and HflK could
EBN15_RS04640	COG0330	HflC and HflK could
EBN15_RS04670	COG0308	aminopeptidase N
EBN15_RS04690	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EBN15_RS04740	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EBN15_RS04745	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EBN15_RS04750	COG2080	2 iron, 2 sulfur cluster binding
EBN15_RS04765	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EBN15_RS04780	COG0587	DNA-directed DNA polymerase activity
EBN15_RS04820	COG1297	OPT oligopeptide transporter protein
EBN15_RS04830	COG0823	Involved in the tonB-independent uptake of proteins
EBN15_RS04830	COG1506	peptidase
EBN15_RS04840	COG1917	Cupin 2, conserved barrel domain protein
EBN15_RS04840	COG2207	Transcriptional regulator
EBN15_RS04860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EBN15_RS04870	COG0753	catalase activity
EBN15_RS04875	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EBN15_RS04875	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EBN15_RS04885	COG3551	Protein conserved in bacteria
EBN15_RS04900	COG2814	Major facilitator Superfamily
EBN15_RS04915	COG2194	sulfuric ester hydrolase activity
EBN15_RS04925	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EBN15_RS04935	COG5002	protein histidine kinase activity
EBN15_RS04945	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EBN15_RS04950	COG2894	cell division
EBN15_RS04955	COG0850	regulation of cytokinetic process
EBN15_RS04965	COG4585	Histidine kinase
EBN15_RS04970	COG2197	response regulator
EBN15_RS04985	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EBN15_RS05010	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EBN15_RS05020	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EBN15_RS05035	COG1946	Acyl-CoA thioesterase
EBN15_RS05045	COG0824	Thioesterase
EBN15_RS05050	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EBN15_RS05055	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EBN15_RS05060	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EBN15_RS05075	COG0728	peptidoglycan biosynthetic process
EBN15_RS05080	COG0196	riboflavin kinase activity
EBN15_RS05090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EBN15_RS05095	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EBN15_RS05110	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EBN15_RS05115	COG1845	cytochrome c oxidase, subunit III
EBN15_RS05120	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EBN15_RS05130	COG0156	8-amino-7-oxononanoate synthase activity
EBN15_RS05150	COG2207	Transcriptional regulator
EBN15_RS05155	COG0326	Molecular chaperone. Has ATPase activity
EBN15_RS05175	COG1366	Belongs to the anti-sigma-factor antagonist family
EBN15_RS05180	COG1366	Belongs to the anti-sigma-factor antagonist family
EBN15_RS05185	COG2172	sigma factor antagonist activity
EBN15_RS05195	COG2205	protein histidine kinase activity
EBN15_RS05205	COG4771	TonB-dependent receptor
EBN15_RS05215	COG5507	3-demethylubiquinone-9 3-methyltransferase
EBN15_RS05220	COG2205	protein histidine kinase activity
EBN15_RS05230	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EBN15_RS05240	COG0784	Response regulator, receiver
EBN15_RS05240	COG4191	Histidine kinase
EBN15_RS05250	COG4566	intracellular signal transduction
EBN15_RS05255	COG4191	Histidine kinase
EBN15_RS05280	COG3534	alpha-L-arabinofuranosidase
EBN15_RS05290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBN15_RS05295	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EBN15_RS05300	COG2070	2-Nitropropane dioxygenase
EBN15_RS05330	COG0534	Mate efflux family protein
EBN15_RS05345	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EBN15_RS05370	COG0523	cobalamin synthesis protein
EBN15_RS05375	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EBN15_RS05390	COG3209	COG3209 Rhs family protein
EBN15_RS05455	COG3250	beta-galactosidase activity
EBN15_RS05460	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EBN15_RS05470	COG1396	sequence-specific DNA binding
EBN15_RS05470	COG3800	Transcriptional regulator
EBN15_RS05480	COG1960	acyl-CoA dehydrogenase activity
EBN15_RS05485	COG1024	Enoyl-CoA hydratase
EBN15_RS05520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBN15_RS05525	COG0481	GTPase activity
EBN15_RS05560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EBN15_RS05570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EBN15_RS05575	COG0493	'glutamate synthase
EBN15_RS05575	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EBN15_RS05580	COG3046	protein related to deoxyribodipyrimidine photolyase
EBN15_RS05585	COG1472	Belongs to the glycosyl hydrolase 3 family
EBN15_RS05595	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EBN15_RS05600	COG1278	Cold shock
EBN15_RS05610	COG1201	RNA secondary structure unwinding
EBN15_RS05615	COG1793	dna ligase
EBN15_RS05625	COG1793	dna ligase
EBN15_RS05625	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EBN15_RS05640	COG0745	RESPONSE REGULATOR receiver
EBN15_RS05640	COG3706	GGDEF domain
EBN15_RS05655	COG0183	Belongs to the thiolase family
EBN15_RS05670	COG1451	nucleotide metabolic process
EBN15_RS05675	COG5487	UPF0391 membrane protein
EBN15_RS05685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EBN15_RS05705	COG1047	Peptidyl-prolyl cis-trans
EBN15_RS05710	COG2824	Alkylphosphonate utilization operon protein PhnA
EBN15_RS05715	COG1902	pentaerythritol trinitrate reductase activity
EBN15_RS05720	COG2814	Major facilitator Superfamily
EBN15_RS05755	COG0392	lysyltransferase activity
EBN15_RS05755	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EBN15_RS05765	COG0251	oxidation-reduction process
EBN15_RS05770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBN15_RS05785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBN15_RS05810	COG1595	DNA-templated transcription, initiation
EBN15_RS05825	COG2878	Part of a membrane complex involved in electron transport
EBN15_RS05835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBN15_RS05835	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBN15_RS05850	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBN15_RS05885	COG0825	malonyl-CoA metabolic process
EBN15_RS05895	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EBN15_RS05900	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBN15_RS05905	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBN15_RS05925	COG0750	zinc metalloprotease
EBN15_RS05930	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EBN15_RS05935	COG0575	Belongs to the CDS family
EBN15_RS05945	COG0233	cytoplasmic translational termination
EBN15_RS05950	COG0528	UMP kinase activity
EBN15_RS05955	COG0745	RESPONSE REGULATOR receiver
EBN15_RS05955	COG3706	GGDEF domain
EBN15_RS05960	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EBN15_RS05965	COG0052	Belongs to the universal ribosomal protein uS2 family
EBN15_RS06000	COG0024	Methionine aminopeptidase
EBN15_RS06005	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EBN15_RS06015	COG1393	Belongs to the ArsC family
EBN15_RS06020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBN15_RS06025	COG0367	asparagine synthase
EBN15_RS06070	COG1566	PFAM secretion protein HlyD family protein
EBN15_RS06075	COG2814	Major facilitator Superfamily
EBN15_RS06115	COG0339	signal peptide processing
EBN15_RS06120	COG0386	Belongs to the glutathione peroxidase family
EBN15_RS06150	COG0288	reversible hydration of carbon dioxide
EBN15_RS06180	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EBN15_RS06185	COG0084	hydrolase, TatD family'
EBN15_RS06200	COG1960	acyl-CoA dehydrogenase activity
EBN15_RS06215	COG0367	asparagine synthase
EBN15_RS06220	COG0305	Participates in initiation and elongation during chromosome replication
EBN15_RS06230	COG0415	Belongs to the DNA photolyase family
EBN15_RS06240	COG0583	DNA-binding transcription factor activity
EBN15_RS06250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBN15_RS06270	COG3706	GGDEF domain
EBN15_RS06285	COG4372	Transposase
EBN15_RS06355	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EBN15_RS06370	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBN15_RS06380	COG0497	DNA recombination
EBN15_RS06385	COG1420	regulation of RNA biosynthetic process
EBN15_RS06390	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EBN15_RS06400	COG0484	heat shock protein binding
EBN15_RS06405	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EBN15_RS06425	COG2274	protein secretion by the type I secretion system
EBN15_RS06435	COG1132	(ABC) transporter
EBN15_RS06470	COG2850	peptidyl-arginine hydroxylation
EBN15_RS06490	COG1253	flavin adenine dinucleotide binding
EBN15_RS06520	COG1131	(ABC) transporter
EBN15_RS06525	COG1725	Transcriptional regulator
EBN15_RS06535	COG0386	Belongs to the glutathione peroxidase family
EBN15_RS06560	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EBN15_RS06560	COG2755	lipolytic protein G-D-S-L family
EBN15_RS06580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBN15_RS06600	COG0646	methionine synthase
EBN15_RS06600	COG1410	methionine synthase
EBN15_RS06610	COG1960	acyl-CoA dehydrogenase activity
EBN15_RS06625	COG0557	exoribonuclease II activity
EBN15_RS06630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBN15_RS06635	COG3706	GGDEF domain
EBN15_RS06640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBN15_RS06645	COG0704	Plays a role in the regulation of phosphate uptake
EBN15_RS06655	COG0581	inorganic phosphate transmembrane transporter activity
EBN15_RS06660	COG0573	inorganic phosphate transmembrane transporter activity
EBN15_RS06665	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EBN15_RS06685	COG4372	Transposase
EBN15_RS06705	COG0659	secondary active sulfate transmembrane transporter activity
EBN15_RS06710	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EBN15_RS06770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EBN15_RS06790	COG2925	Exonuclease
EBN15_RS06795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBN15_RS06800	COG3844	kynureninase activity
EBN15_RS06815	COG0288	reversible hydration of carbon dioxide
EBN15_RS06850	COG0017	Asparaginyl-tRNA synthetase
EBN15_RS06855	COG0316	Belongs to the HesB IscA family
EBN15_RS06865	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EBN15_RS06895	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EBN15_RS06900	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EBN15_RS06925	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EBN15_RS06935	COG2986	histidine ammonia-lyase
EBN15_RS06980	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EBN15_RS06985	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EBN15_RS06990	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EBN15_RS07000	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EBN15_RS07005	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EBN15_RS07015	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EBN15_RS07020	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EBN15_RS07025	COG0583	DNA-binding transcription factor activity
EBN15_RS07080	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EBN15_RS07095	COG1074	ATP-dependent DNA helicase activity
EBN15_RS07115	COG0840	transmembrane signaling receptor activity
EBN15_RS07135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBN15_RS07145	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EBN15_RS07155	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBN15_RS07215	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EBN15_RS07220	COG2244	polysaccharide biosynthetic process
EBN15_RS07245	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EBN15_RS07255	COG0438	transferase activity, transferring glycosyl groups
EBN15_RS07260	COG0438	transferase activity, transferring glycosyl groups
EBN15_RS07275	COG1136	(ABC) transporter
EBN15_RS07280	COG1132	(ABC) transporter
EBN15_RS07285	COG0477	Major facilitator Superfamily
EBN15_RS07290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBN15_RS07305	COG1253	flavin adenine dinucleotide binding
EBN15_RS07320	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EBN15_RS07340	COG0504	CTP synthase activity
EBN15_RS07345	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EBN15_RS07350	COG0148	phosphopyruvate hydratase activity
EBN15_RS07355	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EBN15_RS07365	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EBN15_RS07370	COG0585	pseudouridine synthase activity
EBN15_RS07380	COG2840	Smr protein MutS2
EBN15_RS07385	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EBN15_RS07390	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBN15_RS07395	COG1238	metal cluster binding
EBN15_RS07405	COG3737	Protein of unknown function (DUF498/DUF598)
EBN15_RS07410	COG1534	Rna-binding protein
EBN15_RS07415	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EBN15_RS07420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EBN15_RS07425	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EBN15_RS07430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EBN15_RS07435	COG1923	regulation of RNA biosynthetic process
EBN15_RS07440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EBN15_RS07445	COG1546	Belongs to the CinA family
EBN15_RS07450	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBN15_RS07460	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EBN15_RS07465	COG2137	regulation of response to DNA damage stimulus
EBN15_RS07470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EBN15_RS07475	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EBN15_RS07490	COG1741	Belongs to the pirin family
EBN15_RS07520	COG0351	phosphomethylpyrimidine kinase
EBN15_RS07520	COG0352	thiamine-phosphate diphosphorylase activity
EBN15_RS07530	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EBN15_RS07535	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EBN15_RS07550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBN15_RS07560	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EBN15_RS07565	COG3734	2-keto-3-deoxy-galactonokinase
EBN15_RS07580	COG0800	Aldolase
EBN15_RS07615	COG1501	Belongs to the glycosyl hydrolase 31 family
EBN15_RS07625	COG1070	Carbohydrate kinase
EBN15_RS07630	COG2115	Belongs to the xylose isomerase family
EBN15_RS07635	COG0477	Major facilitator Superfamily
EBN15_RS07700	COG1215	transferase activity, transferring glycosyl groups
EBN15_RS07705	COG1649	PFAM Uncharacterised BCR, COG1649
EBN15_RS07705	COG0726	polysaccharide deacetylase
EBN15_RS07720	COG3210	domain, Protein
EBN15_RS07720	COG3210	domain, Protein
EBN15_RS07745	COG0460	homoserine dehydrogenase
EBN15_RS07745	COG0527	aspartate kinase activity
EBN15_RS07770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EBN15_RS07775	COG0124	histidyl-tRNA synthetase
EBN15_RS07790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EBN15_RS07795	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EBN15_RS07800	COG0131	Imidazoleglycerol-phosphate dehydratase
EBN15_RS07800	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EBN15_RS07805	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EBN15_RS07815	COG0107	imidazoleglycerol-phosphate synthase activity
EBN15_RS07820	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EBN15_RS07820	COG0140	phosphoribosyl-ATP diphosphatase activity
EBN15_RS07835	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
EBN15_RS07850	COG0531	amino acid
EBN15_RS07855	COG0531	amino acid
EBN15_RS07865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EBN15_RS07870	COG0277	FAD linked oxidase domain protein
EBN15_RS07885	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EBN15_RS07900	COG1024	Enoyl-CoA hydratase
EBN15_RS07920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBN15_RS07925	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EBN15_RS07930	COG0505	Belongs to the CarA family
EBN15_RS07945	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EBN15_RS07950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBN15_RS07960	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EBN15_RS07975	COG3279	Response regulator of the LytR AlgR family
EBN15_RS07985	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EBN15_RS08000	COG2198	Histidine kinase
EBN15_RS08000	COG0784	Response regulator, receiver
EBN15_RS08000	COG2205	protein histidine kinase activity
EBN15_RS08005	COG1024	Enoyl-CoA hydratase
EBN15_RS08050	COG0318	PFAM AMP-dependent synthetase and ligase
EBN15_RS08075	COG2267	carboxylic ester hydrolase activity
EBN15_RS08085	COG2201	protein-glutamate methylesterase activity
EBN15_RS08100	COG0840	transmembrane signaling receptor activity
EBN15_RS08110	COG0835	chemotaxis
EBN15_RS08125	COG0840	transmembrane signaling receptor activity
EBN15_RS08130	COG0840	transmembrane signaling receptor activity
EBN15_RS08135	COG0840	transmembrane signaling receptor activity
EBN15_RS08140	COG0840	transmembrane signaling receptor activity
EBN15_RS08145	COG0840	transmembrane signaling receptor activity
EBN15_RS08145	COG0840	transmembrane signaling receptor activity
EBN15_RS08160	COG0745	RESPONSE REGULATOR receiver
EBN15_RS08170	COG0835	chemotaxis
EBN15_RS08175	COG1192	Involved in chromosome partitioning
EBN15_RS08180	COG1360	Flagellar Motor Protein
EBN15_RS08185	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EBN15_RS08215	COG2826	transposase and inactivated derivatives, IS30 family
EBN15_RS08255	COG0643	Histidine kinase
EBN15_RS08255	COG2198	Histidine kinase
EBN15_RS08275	COG0455	bacterial-type flagellum organization
EBN15_RS08320	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EBN15_RS08330	COG5001	Diguanylate cyclase
EBN15_RS08330	COG3300	MHYT domain
EBN15_RS08335	COG3300	MHYT domain
EBN15_RS08335	COG5001	Diguanylate cyclase
EBN15_RS08345	COG1987	bacterial-type flagellum assembly
EBN15_RS08410	COG1677	Flagellar hook-basal body complex protein FliE
EBN15_RS08425	COG4372	Transposase
EBN15_RS08450	COG0489	protein tyrosine kinase activity
EBN15_RS08455	COG0717	Belongs to the dCTP deaminase family
EBN15_RS08485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBN15_RS08495	COG0741	lytic transglycosylase activity
EBN15_RS08500	COG0688	phosphatidylethanolamine metabolic process
EBN15_RS08510	COG2890	protein-(glutamine-N5) methyltransferase activity
EBN15_RS08515	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EBN15_RS08520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBN15_RS08525	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EBN15_RS08555	COG0133	tryptophan synthase activity
EBN15_RS08570	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EBN15_RS08575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBN15_RS08605	COG4221	oxidoreductase activity
EBN15_RS08610	COG0149	triose-phosphate isomerase activity
EBN15_RS08625	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBN15_RS08635	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBN15_RS08640	COG0649	NAD binding
EBN15_RS08645	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EBN15_RS08650	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EBN15_RS08655	COG1034	ATP synthesis coupled electron transport
EBN15_RS08660	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EBN15_RS08675	COG0713	ATP synthesis coupled electron transport
EBN15_RS08690	COG1007	ATP synthesis coupled electron transport
EBN15_RS08700	COG0779	Required for maturation of 30S ribosomal subunits
EBN15_RS08705	COG0195	Participates in both transcription termination and antitermination
EBN15_RS08710	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EBN15_RS08715	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EBN15_RS08720	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EBN15_RS08725	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EBN15_RS08765	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBN15_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
EBN15_RS08775	COG2095	MarC family integral membrane protein
EBN15_RS08785	COG1611	Belongs to the LOG family
EBN15_RS09055	COG4695	Portal protein
EBN15_RS09090	COG0556	nucleotide-excision repair
EBN15_RS09120	COG2948	multi-organism process
EBN15_RS09140	COG3702	type iv secretory pathway
EBN15_RS09330	COG0366	Alpha amylase catalytic
EBN15_RS09340	COG1082	Xylose isomerase domain protein TIM barrel
EBN15_RS09370	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EBN15_RS09375	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EBN15_RS09380	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EBN15_RS09385	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EBN15_RS09390	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EBN15_RS09395	COG0072	phenylalanine-tRNA ligase activity
EBN15_RS09395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBN15_RS09400	COG0776	regulation of translation
EBN15_RS09445	COG0438	transferase activity, transferring glycosyl groups
EBN15_RS09450	COG0438	transferase activity, transferring glycosyl groups
EBN15_RS09455	COG2244	polysaccharide biosynthetic process
EBN15_RS09480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBN15_RS09485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBN15_RS09490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EBN15_RS09510	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EBN15_RS09520	COG1960	acyl-CoA dehydrogenase activity
EBN15_RS09530	COG3040	lipid binding
EBN15_RS09545	COG0784	Response regulator, receiver
EBN15_RS09545	COG4191	Histidine kinase
EBN15_RS09555	COG1194	a g-specific adenine glycosylase
EBN15_RS09565	COG0552	protein localization to endoplasmic reticulum
EBN15_RS09575	COG3938	Belongs to the proline racemase family
EBN15_RS09580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBN15_RS09595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBN15_RS09605	COG0006	proline dipeptidase activity
EBN15_RS09620	COG0531	amino acid
EBN15_RS09645	COG4206	TonB-dependent receptor
EBN15_RS09655	COG3507	Belongs to the glycosyl hydrolase 43 family
EBN15_RS09675	COG3345	alpha-galactosidase
EBN15_RS09690	COG0326	Molecular chaperone. Has ATPase activity
EBN15_RS09695	COG0742	ribosomal rna small subunit methyltransferase
EBN15_RS09700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EBN15_RS09710	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EBN15_RS09715	COG0405	Gamma-glutamyltransferase
EBN15_RS09755	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EBN15_RS09760	COG0343	queuine tRNA-ribosyltransferase activity
EBN15_RS09765	COG1862	Preprotein translocase
EBN15_RS09775	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBN15_RS09815	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBN15_RS09815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBN15_RS09820	COG1105	Belongs to the carbohydrate kinase PfkB family
EBN15_RS09825	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBN15_RS09825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBN15_RS09830	COG1609	Transcriptional regulator
EBN15_RS09835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBN15_RS09840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBN15_RS09850	COG2902	Dehydrogenase
EBN15_RS09865	COG2733	membrane
EBN15_RS09880	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EBN15_RS09885	COG0243	molybdopterin cofactor binding
EBN15_RS09895	COG0477	Major facilitator Superfamily
EBN15_RS09900	COG3706	GGDEF domain
EBN15_RS09900	COG0745	RESPONSE REGULATOR receiver
EBN15_RS10025	COG2857	Cytochrome c1
EBN15_RS10035	COG2969	positive regulation of protein catabolic process
EBN15_RS10070	COG0835	chemotaxis
EBN15_RS10125	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EBN15_RS10340	COG1028	Short-chain dehydrogenase reductase Sdr
EBN15_RS10350	COG0501	Belongs to the peptidase M48B family
EBN15_RS10360	COG2081	HI0933 family
EBN15_RS10365	COG4681	YaeQ
EBN15_RS10385	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EBN15_RS10390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EBN15_RS10395	COG0513	Belongs to the DEAD box helicase family
EBN15_RS10425	COG0483	inositol monophosphate 1-phosphatase activity
EBN15_RS10440	COG3300	MHYT domain
EBN15_RS10440	COG5001	Diguanylate cyclase
EBN15_RS10445	COG1509	lysine 2,3-aminomutase activity
EBN15_RS10455	COG0402	S-adenosylhomocysteine deaminase activity
EBN15_RS10460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EBN15_RS10490	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EBN15_RS10500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EBN15_RS10510	COG2166	iron-sulfur cluster assembly
EBN15_RS10525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EBN15_RS10530	COG0137	argininosuccinate synthase activity
EBN15_RS10540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EBN15_RS10575	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EBN15_RS10600	COG1294	oxidase, subunit
EBN15_RS10610	COG4988	ABC transporter
EBN15_RS10615	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EBN15_RS10625	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBN15_RS10670	COG4133	protoheme IX ABC transporter activity
EBN15_RS10675	COG0436	Aminotransferase
EBN15_RS10705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBN15_RS10720	COG0728	peptidoglycan biosynthetic process
EBN15_RS10730	COG1187	pseudouridine synthase activity
EBN15_RS10735	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EBN15_RS10740	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EBN15_RS10745	COG2350	Protein conserved in bacteria
EBN15_RS10765	COG1175	transmembrane transport
EBN15_RS10770	COG0395	ABC-type sugar transport system, permease component
EBN15_RS10795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBN15_RS10800	COG2957	Belongs to the agmatine deiminase family
EBN15_RS10810	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EBN15_RS10815	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EBN15_RS10820	COG0539	negative regulation of cytoplasmic translation
EBN15_RS10835	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EBN15_RS10840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBN15_RS10850	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EBN15_RS10855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EBN15_RS10855	COG0475	glutathione-regulated potassium exporter activity
EBN15_RS10865	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EBN15_RS10875	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBN15_RS10875	COG0519	Catalyzes the synthesis of GMP from XMP
EBN15_RS10895	COG1914	H( )-stimulated, divalent metal cation uptake system
EBN15_RS10900	COG1321	iron dependent repressor
EBN15_RS10905	COG0590	tRNA wobble adenosine to inosine editing
EBN15_RS10915	COG0668	transmembrane transport
EBN15_RS10925	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EBN15_RS10940	COG1028	Short-chain dehydrogenase reductase Sdr
EBN15_RS10945	COG1183	phosphatidylcholine synthase activity
EBN15_RS10955	COG3243	poly(R)-hydroxyalkanoic acid synthase
EBN15_RS10980	COG2183	response to ionizing radiation
EBN15_RS11055	COG0800	Aldolase
EBN15_RS11060	COG0129	dihydroxy-acid dehydratase activity
EBN15_RS11065	COG0363	glucosamine-6-phosphate deaminase activity
EBN15_RS11070	COG0837	glucose binding
EBN15_RS11075	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBN15_RS11100	COG2009	succinate dehydrogenase
EBN15_RS11105	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EBN15_RS11110	COG1053	succinate dehydrogenase
EBN15_RS11115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EBN15_RS11130	COG4591	ABC-type transport system involved in lipoprotein release permease component
EBN15_RS11135	COG1136	(ABC) transporter
EBN15_RS11145	COG0658	competence protein
EBN15_RS11145	COG2333	competence protein COMEC
EBN15_RS11150	COG0811	peptide transport
EBN15_RS11160	COG1132	(ABC) transporter
EBN15_RS11165	COG1663	tetraacyldisaccharide 4'-kinase activity
EBN15_RS11180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBN15_RS11190	COG0322	excinuclease ABC activity
EBN15_RS11195	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EBN15_RS11235	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EBN15_RS11265	COG1530	ribonuclease E activity
EBN15_RS11275	COG3064	Membrane
EBN15_RS11280	COG0428	transporter
EBN15_RS11290	COG2154	pterin-4-alpha-carbinolamine dehydratase
EBN15_RS11295	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EBN15_RS11295	COG0316	Belongs to the HesB IscA family
EBN15_RS11315	COG0653	protein targeting
EBN15_RS11340	COG3220	belongs to the UPF0276 family
EBN15_RS11345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EBN15_RS11355	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EBN15_RS11355	COG1648	precorrin-2 dehydrogenase activity
EBN15_RS11365	COG0746	molybdenum cofactor guanylyltransferase activity
EBN15_RS11370	COG0303	'Molybdopterin
EBN15_RS11375	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EBN15_RS11385	COG1160	GTP binding
EBN15_RS11390	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBN15_RS11400	COG1426	Protein conserved in bacteria
EBN15_RS11415	COG0105	UTP biosynthetic process
EBN15_RS11425	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBN15_RS11425	COG1024	Enoyl-CoA hydratase
EBN15_RS11430	COG0183	Belongs to the thiolase family
EBN15_RS11435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EBN15_RS11440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EBN15_RS11460	COG1674	ftsk spoiiie
EBN15_RS11465	COG0492	ferredoxin-NADP+ reductase activity
EBN15_RS11475	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EBN15_RS11480	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EBN15_RS11485	COG0542	response to heat
EBN15_RS11500	COG0482	sulfurtransferase activity
EBN15_RS11530	COG4585	Histidine kinase
EBN15_RS11540	COG4191	Histidine kinase
EBN15_RS11560	COG0835	chemotaxis
EBN15_RS11560	COG0784	Response regulator, receiver
EBN15_RS11570	COG1558	bacterial-type flagellum-dependent cell motility
EBN15_RS11575	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EBN15_RS11580	COG1749	Flagellar hook protein flgE
EBN15_RS11585	COG4787	bacterial-type flagellum-dependent cell motility
EBN15_RS11590	COG4786	Flagellar basal body rod
EBN15_RS11600	COG1706	bacterial-type flagellum-dependent cell motility
EBN15_RS11620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EBN15_RS11630	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EBN15_RS11660	COG2201	protein-glutamate methylesterase activity
EBN15_RS11665	COG2204	response regulator
EBN15_RS11680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBN15_RS11690	COG1028	Short-chain dehydrogenase reductase Sdr
EBN15_RS11745	COG4372	Transposase
EBN15_RS11750	COG3590	peptidase
EBN15_RS11755	COG3590	peptidase
EBN15_RS11780	COG2311	Membrane
EBN15_RS11785	COG1047	Peptidyl-prolyl cis-trans
EBN15_RS11790	COG0791	NLP P60 protein
EBN15_RS11795	COG0791	NLP P60 protein
EBN15_RS11810	COG1301	dicarboxylic acid transport
EBN15_RS11815	COG1785	Belongs to the alkaline phosphatase family
EBN15_RS11820	COG0037	tRNA processing
EBN15_RS11825	COG1722	exodeoxyribonuclease VII activity
EBN15_RS11830	COG0142	geranyltranstransferase activity
EBN15_RS11835	COG4104	PAAR repeat-containing protein
EBN15_RS11845	COG0312	modulator of DNA gyrase
EBN15_RS11855	COG0312	modulator of DNA gyrase
EBN15_RS11865	COG3164	Protein of unknown function
EBN15_RS11870	COG1530	ribonuclease E activity
EBN15_RS11880	COG2968	Membrane
EBN15_RS11895	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EBN15_RS11915	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EBN15_RS11940	COG3118	belongs to the thioredoxin family
EBN15_RS11950	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EBN15_RS11995	COG1132	(ABC) transporter
EBN15_RS12000	COG0475	glutathione-regulated potassium exporter activity
EBN15_RS12020	COG3706	GGDEF domain
EBN15_RS12020	COG0745	RESPONSE REGULATOR receiver
EBN15_RS12025	COG1187	pseudouridine synthase activity
EBN15_RS12030	COG5002	protein histidine kinase activity
EBN15_RS12030	COG5001	Diguanylate cyclase
EBN15_RS12135	COG0735	belongs to the Fur family
EBN15_RS12175	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EBN15_RS12185	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EBN15_RS12295	COG0643	Histidine kinase
EBN15_RS12295	COG2198	Histidine kinase
EBN15_RS12305	COG0835	chemotaxis
EBN15_RS12310	COG2202	Pas domain
EBN15_RS12310	COG2200	EAL domain
EBN15_RS12310	COG2199	diguanylate cyclase activity
EBN15_RS12315	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EBN15_RS12330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBN15_RS12335	COG3590	peptidase
EBN15_RS12340	COG0588	phosphoglycerate mutase activity
EBN15_RS12345	COG1515	deoxyribonuclease V activity
EBN15_RS12355	COG1741	Belongs to the pirin family
EBN15_RS12360	COG1966	Carbon starvation protein
EBN15_RS12365	COG2879	small protein
EBN15_RS12400	COG0746	molybdenum cofactor guanylyltransferase activity
EBN15_RS12415	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EBN15_RS12420	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EBN15_RS12425	COG2080	2 iron, 2 sulfur cluster binding
EBN15_RS12430	COG2203	Gaf domain
EBN15_RS12430	COG3706	GGDEF domain
EBN15_RS12430	COG4251	negative regulation of phosphorylation
EBN15_RS12430	COG5001	Diguanylate cyclase
EBN15_RS12460	COG0629	single-stranded DNA binding
EBN15_RS12465	COG0142	geranyltranstransferase activity
EBN15_RS12475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EBN15_RS12490	COG0527	aspartate kinase activity
EBN15_RS12495	COG0384	phenazine biosynthesis protein PhzF
EBN15_RS12500	COG0384	phenazine biosynthesis protein PhzF
EBN15_RS12510	COG1764	response to oxidative stress
EBN15_RS12515	COG0540	Belongs to the ATCase OTCase family
EBN15_RS12520	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EBN15_RS12525	COG1678	Uncharacterized ACR, COG1678
EBN15_RS12530	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EBN15_RS12535	COG0519	Catalyzes the synthesis of GMP from XMP
EBN15_RS12545	COG3039	Transposase
EBN15_RS12560	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EBN15_RS12605	COG1959	2 iron, 2 sulfur cluster binding
EBN15_RS12610	COG0719	Fe-S assembly protein
EBN15_RS12615	COG0396	ATPase activity
EBN15_RS12620	COG0719	Fe-S assembly protein
EBN15_RS12625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EBN15_RS12630	COG0456	acetyltransferase
EBN15_RS12635	COG2146	nitrite reductase [NAD(P)H] activity
EBN15_RS12640	COG4774	siderophore transport
EBN15_RS12645	COG3128	pkhd-type hydroxylase
EBN15_RS12675	COG1477	protein flavinylation
EBN15_RS12695	COG1555	photosystem II stabilization
EBN15_RS12700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBN15_RS12710	COG3178	'Phosphotransferase
EBN15_RS12715	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EBN15_RS12730	COG0628	permease
EBN15_RS12740	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EBN15_RS12755	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EBN15_RS12775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EBN15_RS12780	COG0271	Belongs to the BolA IbaG family
EBN15_RS12790	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EBN15_RS12800	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EBN15_RS12805	COG1137	ATPase activity
EBN15_RS12820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBN15_RS12830	COG1660	Displays ATPase and GTPase activities
EBN15_RS12840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBN15_RS12845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBN15_RS12850	COG2239	Acts as a magnesium transporter
EBN15_RS12860	COG1294	oxidase, subunit
EBN15_RS12865	COG1271	oxidase subunit
EBN15_RS12870	COG1113	amino acid transport
EBN15_RS12895	COG2197	response regulator
EBN15_RS12900	COG0531	amino acid
EBN15_RS12935	COG3039	Transposase
EBN15_RS12970	COG0754	glutathionylspermidine amidase activity
EBN15_RS12995	COG1842	Phage shock protein A
EBN15_RS13010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EBN15_RS13015	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EBN15_RS13025	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EBN15_RS13105	COG2814	Major facilitator Superfamily
EBN15_RS13120	COG2353	YceI-like domain
EBN15_RS13135	COG1278	Cold shock
EBN15_RS13145	COG1760	l-serine dehydratase
EBN15_RS13155	COG0527	aspartate kinase activity
EBN15_RS13155	COG0460	homoserine dehydrogenase
EBN15_RS13160	COG0626	cystathionine gamma-synthase activity
EBN15_RS13165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBN15_RS13170	COG0739	heme binding
EBN15_RS13180	COG1272	protein, Hemolysin III
EBN15_RS13185	COG2982	Protein involved in outer membrane biogenesis
EBN15_RS13190	COG0463	Glycosyl transferase, family 2
EBN15_RS13195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EBN15_RS13200	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EBN15_RS13220	COG0457	Tetratricopeptide repeat
EBN15_RS13245	COG1309	transcriptional regulator
EBN15_RS13255	COG1960	acyl-CoA dehydrogenase activity
EBN15_RS13285	COG0509	glycine decarboxylation via glycine cleavage system
EBN15_RS13290	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EBN15_RS13300	COG0330	HflC and HflK could
EBN15_RS13320	COG0494	nUDIX hydrolase
EBN15_RS13330	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EBN15_RS13335	COG0837	glucose binding
EBN15_RS13355	COG3858	chitin binding
EBN15_RS13355	COG1388	LysM domain
EBN15_RS13420	COG1486	melibiose metabolic process
EBN15_RS13430	COG3537	Alpha-1,2-mannosidase
EBN15_RS13455	COG3645	SOS response
EBN15_RS13470	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EBN15_RS13495	COG3142	Participates in the control of copper homeostasis
EBN15_RS13500	COG1446	asparaginase
EBN15_RS13525	COG0840	transmembrane signaling receptor activity
EBN15_RS13530	COG0835	chemotaxis
EBN15_RS13545	COG0189	ligase activity
EBN15_RS13565	COG1199	ATP-dependent helicase activity
EBN15_RS13575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EBN15_RS13580	COG1216	Glycosyl transferase, family 2
EBN15_RS13595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBN15_RS13605	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EBN15_RS13610	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
EBN15_RS13620	COG0535	radical SAM domain protein
EBN15_RS13635	COG1643	Atp-dependent helicase
EBN15_RS13640	COG0783	Belongs to the Dps family
EBN15_RS13645	COG0514	ATP-dependent DNA helicase (RecQ)
EBN15_RS13665	COG1187	pseudouridine synthase activity
EBN15_RS13690	COG0602	queuosine metabolic process
EBN15_RS13700	COG2885	chlorophyll binding
EBN15_RS13705	COG0823	Involved in the tonB-independent uptake of proteins
EBN15_RS13715	COG0848	biopolymer transport protein
EBN15_RS13725	COG0824	Thioesterase
EBN15_RS13740	COG0632	four-way junction helicase activity
EBN15_RS13745	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EBN15_RS13750	COG0217	transcriptional regulatory protein
EBN15_RS13820	COG0488	(ABC) transporter
EBN15_RS13840	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EBN15_RS13840	COG4651	solute:proton antiporter activity
EBN15_RS13925	COG4772	TonB-dependent receptor
EBN15_RS13935	COG4264	IucA IucC family
EBN15_RS13940	COG2814	Major facilitator Superfamily
EBN15_RS13950	COG0019	diaminopimelate decarboxylase activity
EBN15_RS13965	COG1492	cobalamin metabolic process
EBN15_RS13980	COG4206	TonB-dependent receptor
EBN15_RS13995	COG0542	response to heat
EBN15_RS14050	COG2985	domain, Protein
EBN15_RS14060	COG1877	trehalose-phosphatase activity
EBN15_RS14065	COG3387	PFAM Glycoside hydrolase 15-related
EBN15_RS14070	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EBN15_RS14075	COG0840	transmembrane signaling receptor activity
EBN15_RS14080	COG3011	Protein conserved in bacteria
EBN15_RS14095	COG0564	pseudouridine synthase activity
EBN15_RS14100	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBN15_RS14105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBN15_RS14105	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EBN15_RS14110	COG2852	Protein conserved in bacteria
EBN15_RS14115	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EBN15_RS14120	COG0045	succinate-CoA ligase (ADP-forming) activity
EBN15_RS14135	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBN15_RS14150	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EBN15_RS14155	COG0237	dephospho-CoA kinase activity
EBN15_RS14160	COG5002	protein histidine kinase activity
EBN15_RS14165	COG0745	RESPONSE REGULATOR receiver
EBN15_RS14175	COG0189	ligase activity
EBN15_RS14260	COG1196	nuclear chromosome segregation
EBN15_RS14325	COG0616	signal peptide processing
EBN15_RS14340	COG2856	Zn peptidase
EBN15_RS14545	COG0582	viral genome integration into host DNA
EBN15_RS14570	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EBN15_RS14575	COG0471	metal ion transport
EBN15_RS14575	COG3273	potassium ion transport
EBN15_RS14605	COG1609	Transcriptional regulator
EBN15_RS14615	COG5297	Belongs to the glycosyl hydrolase family 6
EBN15_RS14625	COG3250	beta-galactosidase activity
EBN15_RS14630	COG4948	Mandelate Racemase Muconate Lactonizing
EBN15_RS14645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBN15_RS14655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBN15_RS14660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBN15_RS14665	COG2895	sulfate adenylyltransferase (ATP) activity
EBN15_RS14665	COG0529	Catalyzes the synthesis of activated sulfate
EBN15_RS14675	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBN15_RS14680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EBN15_RS14710	COG2205	protein histidine kinase activity
EBN15_RS14710	COG0784	Response regulator, receiver
EBN15_RS14710	COG2198	Histidine kinase
EBN15_RS14720	COG1648	precorrin-2 dehydrogenase activity
EBN15_RS14720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EBN15_RS14735	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EBN15_RS14740	COG3588	fructose-bisphosphate aldolase
EBN15_RS14745	COG0469	pyruvate kinase activity
EBN15_RS14775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EBN15_RS14785	COG3047	cAMP biosynthetic process
EBN15_RS14800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBN15_RS14800	COG3453	Protein conserved in bacteria
EBN15_RS14805	COG0725	ABC transporter, periplasmic molybdate-binding protein
EBN15_RS14810	COG4149	molybdate abc transporter
EBN15_RS14815	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EBN15_RS14840	COG1376	ErfK ybiS ycfS ynhG family protein
EBN15_RS14845	COG0739	heme binding
EBN15_RS14850	COG4773	Receptor
EBN15_RS14855	COG0596	Alpha beta hydrolase
EBN15_RS14865	COG1301	dicarboxylic acid transport
EBN15_RS14875	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EBN15_RS14880	COG1012	belongs to the aldehyde dehydrogenase family
EBN15_RS14885	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EBN15_RS14890	COG1012	belongs to the aldehyde dehydrogenase family
EBN15_RS14895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBN15_RS14900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EBN15_RS14905	COG2267	carboxylic ester hydrolase activity
EBN15_RS14930	COG2304	oxidoreductase activity
EBN15_RS14950	COG0714	Associated with various cellular activities
EBN15_RS14980	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EBN15_RS15000	COG1957	nucleoside hydrolase
EBN15_RS15005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EBN15_RS15015	COG2721	sulfolactate sulfo-lyase activity
EBN15_RS15030	COG2271	Major facilitator Superfamily
EBN15_RS15045	COG0583	DNA-binding transcription factor activity
EBN15_RS15050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBN15_RS15055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EBN15_RS15060	COG2390	Transcriptional regulator
EBN15_RS15070	COG3039	Transposase
EBN15_RS15100	COG1028	Short-chain dehydrogenase reductase Sdr
EBN15_RS15110	COG1758	RNA polymerase activity
EBN15_RS15115	COG0194	GDP metabolic process
EBN15_RS15120	COG1561	YicC-like family, N-terminal region
EBN15_RS15125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EBN15_RS15135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EBN15_RS15150	COG0006	proline dipeptidase activity
EBN15_RS15160	COG0006	proline dipeptidase activity
EBN15_RS15185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EBN15_RS15205	COG2912	Transglutaminase-like superfamily
EBN15_RS15210	COG1773	rubredoxin
EBN15_RS15215	COG0352	thiamine-phosphate diphosphorylase activity
EBN15_RS15225	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EBN15_RS15235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EBN15_RS15240	COG0300	oxidoreductase activity
EBN15_RS15265	COG2826	transposase and inactivated derivatives, IS30 family
EBN15_RS15295	COG3781	membrane
EBN15_RS15305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBN15_RS15310	COG0563	adenylate kinase activity
EBN15_RS15330	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EBN15_RS15335	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EBN15_RS15365	COG0823	Involved in the tonB-independent uptake of proteins
EBN15_RS15375	COG0840	transmembrane signaling receptor activity
EBN15_RS15380	COG0405	Gamma-glutamyltransferase
EBN15_RS15385	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EBN15_RS15405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EBN15_RS15410	COG0473	3-isopropylmalate dehydrogenase activity
EBN15_RS15415	COG0066	3-isopropylmalate dehydratase activity
EBN15_RS15430	COG3706	GGDEF domain
EBN15_RS15440	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBN15_RS15445	COG1538	Outer membrane efflux protein
EBN15_RS15450	COG1519	Transferase
EBN15_RS15455	COG1560	Kdo2-lipid A biosynthetic process
EBN15_RS15465	COG0438	transferase activity, transferring glycosyl groups
EBN15_RS15495	COG0280	phosphate acetyltransferase
EBN15_RS15495	COG0281	malic enzyme
EBN15_RS15510	COG4191	Histidine kinase
EBN15_RS15515	COG2197	response regulator
EBN15_RS15520	COG1840	ABC-type Fe3 transport system, periplasmic component
EBN15_RS15525	COG0642	Histidine kinase
EBN15_RS15540	COG2851	Citrate transporter
EBN15_RS15545	COG1028	Short-chain dehydrogenase reductase Sdr
EBN15_RS15550	COG1609	Transcriptional regulator
EBN15_RS15555	COG2211	Major facilitator Superfamily
EBN15_RS15580	COG1162	GTPase activity
EBN15_RS15620	COG0436	Aminotransferase
EBN15_RS15640	COG0726	polysaccharide deacetylase
EBN15_RS15645	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBN15_RS15665	COG3964	amidohydrolase
EBN15_RS15670	COG0402	S-adenosylhomocysteine deaminase activity
EBN15_RS15680	COG1307	EDD domain protein, DegV family
EBN15_RS15690	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EBN15_RS15710	COG0745	RESPONSE REGULATOR receiver
EBN15_RS15715	COG2205	protein histidine kinase activity
EBN15_RS15740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EBN15_RS15750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EBN15_RS15755	COG1012	belongs to the aldehyde dehydrogenase family
EBN15_RS15760	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EBN15_RS15805	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EBN15_RS15810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBN15_RS15815	COG1609	Transcriptional regulator
EBN15_RS15850	COG4795	General secretion pathway protein
EBN15_RS15870	COG1459	type II secretion system
EBN15_RS15915	COG1028	Short-chain dehydrogenase reductase Sdr
EBN15_RS15920	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EBN15_RS15925	COG4191	Histidine kinase
EBN15_RS15930	COG0784	Response regulator, receiver
EBN15_RS15935	COG4251	negative regulation of phosphorylation
EBN15_RS15940	COG2823	Periplasmic or secreted lipoprotein
EBN15_RS15945	COG0673	inositol 2-dehydrogenase activity
EBN15_RS15950	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EBN15_RS16045	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EBN15_RS16065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EBN15_RS16070	COG0321	lipoyl(octanoyl) transferase activity
EBN15_RS16085	COG1686	Belongs to the peptidase S11 family
EBN15_RS16095	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EBN15_RS16100	COG2951	lytic endotransglycosylase activity
EBN15_RS16105	COG5434	Belongs to the glycosyl hydrolase 28 family
EBN15_RS16110	COG0772	Belongs to the SEDS family
EBN15_RS16125	COG1792	Involved in formation and maintenance of cell shape
EBN15_RS16130	COG1077	Cell shape determining protein MreB Mrl
EBN15_RS16150	COG0308	aminopeptidase N
EBN15_RS16155	COG5001	Diguanylate cyclase
EBN15_RS16155	COG3300	MHYT domain
EBN15_RS16160	COG2226	methyltransferase
EBN15_RS16170	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EBN15_RS16175	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EBN15_RS16180	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EBN15_RS16190	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EBN15_RS16200	COG2832	Protein of unknown function (DUF454)
EBN15_RS16215	COG1505	serine-type exopeptidase activity
EBN15_RS16240	COG0181	hydroxymethylbilane synthase activity
EBN15_RS16250	COG3275	phosphorelay sensor kinase activity
EBN15_RS16260	COG2943	transferase activity, transferring hexosyl groups
EBN15_RS16270	COG3706	GGDEF domain
EBN15_RS16275	COG0659	secondary active sulfate transmembrane transporter activity
EBN15_RS16280	COG5297	Belongs to the glycosyl hydrolase family 6
EBN15_RS16280	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBN15_RS16315	COG0598	Magnesium transport protein CorA
EBN15_RS16320	COG1113	amino acid transport
EBN15_RS16325	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBN15_RS16325	COG5297	Belongs to the glycosyl hydrolase family 6
EBN15_RS16340	COG0697	spore germination
EBN15_RS16355	COG1959	2 iron, 2 sulfur cluster binding
EBN15_RS16360	COG3706	GGDEF domain
EBN15_RS16380	COG0823	Involved in the tonB-independent uptake of proteins
EBN15_RS16380	COG1506	peptidase
EBN15_RS16415	COG0435	Glutathione S-transferase
EBN15_RS16425	COG1802	Transcriptional regulator
EBN15_RS16440	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EBN15_RS16460	COG3052	prosthetic group binding
EBN15_RS16480	COG2353	YceI-like domain
EBN15_RS16485	COG0778	Nitroreductase
EBN15_RS16495	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBN15_RS16500	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EBN15_RS16515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EBN15_RS16520	COG3550	peptidyl-serine autophosphorylation
EBN15_RS16545	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EBN15_RS16550	COG2356	endonuclease I
EBN15_RS16555	COG1324	tolerance protein
EBN15_RS16565	COG1505	serine-type exopeptidase activity
EBN15_RS16570	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EBN15_RS16575	COG0511	ligase activity, forming carbon-carbon bonds
EBN15_RS16585	COG0439	Biotin carboxylase
EBN15_RS16600	COG2264	protein methyltransferase activity
EBN15_RS16620	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EBN15_RS16625	COG4589	Belongs to the CDS family
EBN15_RS16645	COG2453	phosphatase
EBN15_RS16645	COG0671	phosphoesterase, PA-phosphatase related
EBN15_RS16655	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EBN15_RS16660	COG0138	bifunctional purine biosynthesis protein purh
EBN15_RS16665	COG0151	Belongs to the GarS family
EBN15_RS16670	COG0577	efflux transmembrane transporter activity
EBN15_RS16670	COG1136	(ABC) transporter
EBN15_RS16680	COG1289	transmembrane transporter activity
EBN15_RS16685	COG2814	Major facilitator Superfamily
EBN15_RS16700	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EBN15_RS16705	COG2816	NAD+ diphosphatase activity
EBN15_RS16710	COG0316	Belongs to the HesB IscA family
EBN15_RS16770	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EBN15_RS16800	COG0134	indole-3-glycerol-phosphate synthase activity
EBN15_RS16805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EBN15_RS16880	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EBN15_RS16935	COG5297	Belongs to the glycosyl hydrolase family 6
EBN15_RS16950	COG4372	Transposase
EBN15_RS16995	COG3039	Transposase
EBN15_RS17030	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
EBN15_RS17070	COG1518	maintenance of DNA repeat elements
EBN15_RS17075	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EBN15_RS17090	COG4372	Transposase
EBN15_RS17110	COG4372	Transposase
EBN15_RS17145	COG0339	signal peptide processing
EBN15_RS17200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBN15_RS17210	COG1136	(ABC) transporter
EBN15_RS17210	COG4591	ABC-type transport system involved in lipoprotein release permease component
EBN15_RS17220	COG1136	(ABC) transporter
EBN15_RS17220	COG0577	efflux transmembrane transporter activity
EBN15_RS17235	COG4191	Histidine kinase
EBN15_RS17240	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EBN15_RS17255	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EBN15_RS17260	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EBN15_RS17265	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EBN15_RS17275	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EBN15_RS17280	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EBN15_RS17290	COG0356	it plays a direct role in the translocation of protons across the membrane
EBN15_RS17305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EBN15_RS17315	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBN15_RS17345	COG2011	ABC-type metal ion transport system permease component
EBN15_RS17350	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EBN15_RS17355	COG0697	spore germination
EBN15_RS17360	COG1666	GTP binding
EBN15_RS17390	COG1187	pseudouridine synthase activity
EBN15_RS17395	COG2813	Specifically methylates the guanine in position
EBN15_RS17410	COG2202	Pas domain
EBN15_RS17410	COG2205	protein histidine kinase activity
EBN15_RS17430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EBN15_RS17435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBN15_RS17440	COG1522	sequence-specific DNA binding
EBN15_RS17485	COG0842	Transport permease protein
EBN15_RS17490	COG1131	(ABC) transporter
EBN15_RS17495	COG0025	NhaP-type Na H and K H
EBN15_RS17505	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EBN15_RS17510	COG1573	uracil-dna glycosylase
EBN15_RS17520	COG3384	dioxygenase
EBN15_RS17530	COG0583	DNA-binding transcription factor activity
EBN15_RS17540	COG0667	Aldo Keto reductase
EBN15_RS17550	COG3590	peptidase
EBN15_RS17565	COG0531	amino acid
EBN15_RS17580	COG2972	Histidine kinase
EBN15_RS17590	COG3685	Protein conserved in bacteria
EBN15_RS17600	COG2204	response regulator
EBN15_RS17610	COG1028	Short-chain dehydrogenase reductase Sdr
EBN15_RS17785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBN15_RS17795	COG1560	Kdo2-lipid A biosynthetic process
EBN15_RS17805	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EBN15_RS17840	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EBN15_RS17840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBN15_RS17845	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EBN15_RS17850	COG0242	peptide deformylase activity
EBN15_RS17855	COG1652	LysM domain
EBN15_RS17860	COG0758	DNA mediated transformation
EBN15_RS17880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBN15_RS17880	COG1754	DNA topoisomerase type I activity
EBN15_RS17885	COG0009	L-threonylcarbamoyladenylate synthase
EBN15_RS17900	COG1028	Short-chain dehydrogenase reductase Sdr
EBN15_RS17910	COG0616	signal peptide processing
EBN15_RS17915	COG0534	Mate efflux family protein
EBN15_RS17930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EBN15_RS17945	COG1252	NADH dehydrogenase
EBN15_RS17950	COG2860	membrane
EBN15_RS17955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBN15_RS17960	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EBN15_RS17965	COG3437	response regulator, receiver
EBN15_RS17970	COG2177	Part of the ABC transporter FtsEX involved in
EBN15_RS17975	COG2884	Cell division ATP-binding protein ftsE
EBN15_RS17980	COG0513	Belongs to the DEAD box helicase family
EBN15_RS17985	COG3118	belongs to the thioredoxin family
EBN15_RS17990	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EBN15_RS18000	COG1473	amidohydrolase
EBN15_RS18005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBN15_RS18010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBN15_RS18020	COG5383	Protein conserved in bacteria
EBN15_RS18055	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EBN15_RS18060	COG3023	N-Acetylmuramoyl-L-alanine amidase
EBN15_RS18070	COG4948	Mandelate Racemase Muconate Lactonizing
EBN15_RS18080	COG0531	amino acid
EBN15_RS18090	COG4682	membrane
EBN15_RS18095	COG2133	pyrroloquinoline quinone binding
EBN15_RS18105	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EBN15_RS18110	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EBN15_RS18115	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EBN15_RS18120	COG1610	YqeY-like protein
EBN15_RS18125	COG1295	ribonuclease BN
EBN15_RS18130	COG0358	DNA primase activity
EBN15_RS18150	COG0109	protoheme IX farnesyltransferase activity
EBN15_RS18180	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EBN15_RS18195	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EBN15_RS18260	COG0739	heme binding
EBN15_RS18275	COG2211	Major facilitator Superfamily
EBN15_RS18280	COG0708	Exodeoxyribonuclease III
EBN15_RS18295	COG1192	Involved in chromosome partitioning
EBN15_RS18300	COG1475	DNA binding
EBN15_RS18320	COG0463	Glycosyl transferase, family 2
EBN15_RS18340	COG0756	dUTP diphosphatase activity
EBN15_RS18345	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EBN15_RS18355	COG0018	arginyl-trna synthetase
EBN15_RS18370	COG4221	oxidoreductase activity
EBN15_RS18375	COG2755	lipolytic protein G-D-S-L family
EBN15_RS18375	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EBN15_RS18380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EBN15_RS18390	COG1166	arginine decarboxylase activity
EBN15_RS18395	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EBN15_RS18425	COG0606	chelatase, subunit chli
EBN15_RS18440	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EBN15_RS18480	COG1090	epimerase
EBN15_RS18490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBN15_RS18515	COG1011	Hydrolase
EBN15_RS18520	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBN15_RS18540	COG2197	response regulator
EBN15_RS18545	COG4585	Histidine kinase
EBN15_RS18550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBN15_RS18555	COG1136	(ABC) transporter
EBN15_RS18580	COG0697	spore germination
EBN15_RS18595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBN15_RS18600	COG0180	Tryptophanyl-tRNA synthetase
EBN15_RS18605	COG3237	CsbD-like
EBN15_RS18645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EBN15_RS18675	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EBN15_RS18680	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EBN15_RS18680	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EBN15_RS18705	COG2205	protein histidine kinase activity
EBN15_RS18710	COG0745	RESPONSE REGULATOR receiver
EBN15_RS18720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBN15_RS18740	COG1199	ATP-dependent helicase activity
EBN15_RS18750	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EBN15_RS18815	COG0625	glutathione transferase activity
EBN15_RS18850	COG4555	ABC transporter
EBN15_RS18860	COG1476	TRANSCRIPTIONal
EBN15_RS18875	COG1230	cation diffusion facilitator family transporter
EBN15_RS18880	COG0633	Ferredoxin
EBN15_RS18880	COG0543	2 iron, 2 sulfur cluster binding
EBN15_RS18885	COG1131	(ABC) transporter
EBN15_RS18890	COG0842	Transport permease protein
EBN15_RS18900	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EBN15_RS18910	COG1607	acyl-coa hydrolase
EBN15_RS18935	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBN15_RS18940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBN15_RS18950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EBN15_RS18950	COG1042	CoA-binding domain protein
EBN15_RS18950	COG0045	succinate-CoA ligase (ADP-forming) activity
EBN15_RS18955	COG2239	Acts as a magnesium transporter
EBN15_RS18965	COG0339	signal peptide processing
EBN15_RS18970	COG1446	asparaginase
EBN15_RS18990	COG0564	pseudouridine synthase activity
EBN15_RS19010	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBN15_RS19020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EBN15_RS19025	COG0318	PFAM AMP-dependent synthetase and ligase
EBN15_RS19035	COG0596	Alpha beta hydrolase
EBN15_RS19040	COG3177	Filamentation induced by cAMP protein fic
EBN15_RS19045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBN15_RS19060	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EBN15_RS19080	COG2204	response regulator
EBN15_RS19090	COG0028	Belongs to the TPP enzyme family
EBN15_RS19100	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EBN15_RS19110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EBN15_RS19150	COG0183	Belongs to the thiolase family
EBN15_RS19170	COG2032	superoxide dismutase activity
EBN15_RS19175	COG2032	superoxide dismutase activity
EBN15_RS19180	COG2204	response regulator
EBN15_RS19185	COG3852	Histidine kinase
EBN15_RS19190	COG0004	ammonium transporteR
EBN15_RS19195	COG0347	Belongs to the P(II) protein family
EBN15_RS19200	COG0174	glutamine synthetase
EBN15_RS19230	COG2050	protein possibly involved in aromatic compounds catabolism
EBN15_RS19235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBN15_RS19245	COG2062	phosphohistidine phosphatase, SixA
EBN15_RS19250	COG0489	protein tyrosine kinase activity
EBN15_RS19270	COG1396	sequence-specific DNA binding
EBN15_RS19275	COG3550	peptidyl-serine autophosphorylation
EBN15_RS19285	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EBN15_RS19290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBN15_RS19305	COG0517	IMP dehydrogenase activity
EBN15_RS19305	COG1125	glycine betaine transport
EBN15_RS19310	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EBN15_RS19320	COG1119	ATPase activity
EBN15_RS19330	COG1752	Esterase of the alpha-beta hydrolase superfamily
EBN15_RS19335	COG1522	sequence-specific DNA binding
EBN15_RS19340	COG3186	Phenylalanine-4-hydroxylase
EBN15_RS19350	COG2755	lipolytic protein G-D-S-L family
EBN15_RS19360	COG1028	Short-chain dehydrogenase reductase Sdr
EBN15_RS19365	COG1609	Transcriptional regulator
EBN15_RS19370	COG3507	Belongs to the glycosyl hydrolase 43 family
EBN15_RS19385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EBN15_RS19395	COG0657	acetylesterase activity
EBN15_RS19395	COG2755	lipolytic protein G-D-S-L family
EBN15_RS19415	COG0366	Alpha amylase catalytic
EBN15_RS19420	COG0366	Alpha amylase catalytic
EBN15_RS19435	COG2911	Protein conserved in bacteria
EBN15_RS19440	COG0729	surface antigen
EBN15_RS19445	COG4771	TonB-dependent receptor
EBN15_RS19450	COG0457	Tetratricopeptide repeat
EBN15_RS19460	COG0752	glycyl-tRNA synthetase alpha subunit
EBN15_RS19465	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBN15_RS19470	COG0519	Catalyzes the synthesis of GMP from XMP
EBN15_RS19470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBN15_RS19480	COG0805	protein transport
EBN15_RS19485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBN15_RS19490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBN15_RS19500	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EBN15_RS19505	COG0596	Alpha beta hydrolase
EBN15_RS19515	COG2974	May be involved in recombination
EBN15_RS19520	COG0037	tRNA processing
EBN15_RS19525	COG2115	Belongs to the xylose isomerase family
EBN15_RS19535	COG3661	Belongs to the glycosyl hydrolase 67 family
EBN15_RS19545	COG4948	Mandelate Racemase Muconate Lactonizing
EBN15_RS19550	COG3507	Belongs to the glycosyl hydrolase 43 family
EBN15_RS19555	COG1472	Belongs to the glycosyl hydrolase 3 family
EBN15_RS19560	COG0246	Mannitol dehydrogenase
EBN15_RS19625	COG2211	Major facilitator Superfamily
EBN15_RS19630	COG1172	Belongs to the binding-protein-dependent transport system permease family
EBN15_RS19635	COG1172	Belongs to the binding-protein-dependent transport system permease family
EBN15_RS19640	COG1129	ABC transporter
EBN15_RS19645	COG1879	ABC-type sugar transport system periplasmic component
EBN15_RS19660	COG0129	dihydroxy-acid dehydratase activity
EBN15_RS19665	COG3386	PFAM SMP-30 Gluconolaconase
EBN15_RS19680	COG3250	beta-galactosidase activity
EBN15_RS19685	COG1904	glucuronate isomerase
EBN15_RS19690	COG3693	PFAM glycoside hydrolase, family 10
EBN15_RS19705	COG2211	Major facilitator Superfamily
EBN15_RS19715	COG0393	Putative heavy-metal-binding
EBN15_RS19740	COG2937	Belongs to the GPAT DAPAT family
EBN15_RS19765	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EBN15_RS19770	COG3132	Protein of unknown function, DUF480
EBN15_RS19780	COG0210	DNA helicase
EBN15_RS19785	COG1435	thymidine kinase activity
EBN15_RS19795	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EBN15_RS19855	COG2951	lytic endotransglycosylase activity
EBN15_RS19860	COG0531	amino acid
EBN15_RS19865	COG3537	Alpha-1,2-mannosidase
EBN15_RS19870	COG3706	GGDEF domain
EBN15_RS19875	COG1929	Belongs to the glycerate kinase type-1 family
EBN15_RS19900	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBN15_RS19905	COG0861	Integral membrane protein TerC family
EBN15_RS19915	COG0584	glycerophosphoryl diester phosphodiesterase
EBN15_RS19945	COG0706	membrane insertase activity
EBN15_RS19955	COG0230	Belongs to the bacterial ribosomal protein bL34 family