locus-tag	class	description
XJ27_RS00015	COG0477	Major facilitator Superfamily
XJ27_RS00025	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XJ27_RS00035	COG2986	histidine ammonia-lyase
XJ27_RS00040	COG1228	amidohydrolase
XJ27_RS00075	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XJ27_RS00080	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XJ27_RS00085	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XJ27_RS00090	COG1605	Chorismate mutase
XJ27_RS00090	COG0077	Prephenate dehydratase
XJ27_RS00095	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XJ27_RS00110	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XJ27_RS00120	COG0583	DNA-binding transcription factor activity
XJ27_RS00185	COG2003	Belongs to the UPF0758 family
XJ27_RS00205	COG2189	Belongs to the N(4) N(6)-methyltransferase family
XJ27_RS00260	COG3039	Transposase
XJ27_RS00325	COG0840	transmembrane signaling receptor activity
XJ27_RS00345	COG0784	Response regulator, receiver
XJ27_RS00345	COG5002	protein histidine kinase activity
XJ27_RS00345	COG2205	protein histidine kinase activity
XJ27_RS00350	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XJ27_RS00355	COG0784	Response regulator, receiver
XJ27_RS00355	COG4191	Histidine kinase
XJ27_RS00360	COG3039	Transposase
XJ27_RS00375	COG2879	small protein
XJ27_RS00380	COG1966	Carbon starvation protein
XJ27_RS00385	COG1741	Belongs to the pirin family
XJ27_RS00400	COG1741	Belongs to the pirin family
XJ27_RS00405	COG1515	deoxyribonuclease V activity
XJ27_RS00420	COG3590	peptidase
XJ27_RS00425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XJ27_RS00435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XJ27_RS00445	COG0835	chemotaxis
XJ27_RS00450	COG0840	transmembrane signaling receptor activity
XJ27_RS00455	COG2198	Histidine kinase
XJ27_RS00455	COG0643	Histidine kinase
XJ27_RS00465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XJ27_RS00480	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XJ27_RS00485	COG0745	RESPONSE REGULATOR receiver
XJ27_RS00490	COG2205	protein histidine kinase activity
XJ27_RS00500	COG4452	Inner membrane protein CreD
XJ27_RS00525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XJ27_RS00530	COG0735	belongs to the Fur family
XJ27_RS00555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XJ27_RS00565	COG1309	transcriptional regulator
XJ27_RS00570	COG0667	Aldo Keto reductase
XJ27_RS00595	COG0583	DNA-binding transcription factor activity
XJ27_RS00600	COG2814	Major facilitator Superfamily
XJ27_RS00605	COG0667	Aldo Keto reductase
XJ27_RS00610	COG1404	Belongs to the peptidase S8 family
XJ27_RS00620	COG1404	Belongs to the peptidase S8 family
XJ27_RS00715	COG1595	DNA-templated transcription, initiation
XJ27_RS00725	COG5001	Diguanylate cyclase
XJ27_RS00725	COG5002	protein histidine kinase activity
XJ27_RS00730	COG1187	pseudouridine synthase activity
XJ27_RS00750	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XJ27_RS00760	COG0475	glutathione-regulated potassium exporter activity
XJ27_RS00770	COG1132	(ABC) transporter
XJ27_RS00810	COG2155	Conserved Protein
XJ27_RS00820	COG0583	DNA-binding transcription factor activity
XJ27_RS00835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XJ27_RS00865	COG3706	GGDEF domain
XJ27_RS00920	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XJ27_RS00935	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XJ27_RS00945	COG0497	DNA recombination
XJ27_RS00950	COG1420	regulation of RNA biosynthetic process
XJ27_RS00955	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XJ27_RS00970	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XJ27_RS00995	COG2274	protein secretion by the type I secretion system
XJ27_RS01000	COG0583	DNA-binding transcription factor activity
XJ27_RS01005	COG1132	(ABC) transporter
XJ27_RS01040	COG2850	peptidyl-arginine hydroxylation
XJ27_RS01060	COG1253	flavin adenine dinucleotide binding
XJ27_RS01090	COG1131	(ABC) transporter
XJ27_RS01095	COG1725	Transcriptional regulator
XJ27_RS01105	COG0386	Belongs to the glutathione peroxidase family
XJ27_RS01120	COG2900	Belongs to the SlyX family
XJ27_RS01145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XJ27_RS01160	COG1410	methionine synthase
XJ27_RS01160	COG0646	methionine synthase
XJ27_RS01170	COG2226	methyltransferase
XJ27_RS01175	COG1960	acyl-CoA dehydrogenase activity
XJ27_RS01180	COG3039	Transposase
XJ27_RS01195	COG0557	exoribonuclease II activity
XJ27_RS01205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XJ27_RS01225	COG0704	Plays a role in the regulation of phosphate uptake
XJ27_RS01235	COG0581	inorganic phosphate transmembrane transporter activity
XJ27_RS01240	COG0573	inorganic phosphate transmembrane transporter activity
XJ27_RS01245	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XJ27_RS01270	COG0659	secondary active sulfate transmembrane transporter activity
XJ27_RS01280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XJ27_RS01290	COG1024	Enoyl-CoA hydratase
XJ27_RS01335	COG0488	(ABC) transporter
XJ27_RS01350	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XJ27_RS01360	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XJ27_RS01375	COG2925	Exonuclease
XJ27_RS01380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XJ27_RS01400	COG0288	reversible hydration of carbon dioxide
XJ27_RS01405	COG2808	Putative FMN-binding domain
XJ27_RS01420	COG0017	Asparaginyl-tRNA synthetase
XJ27_RS01430	COG0316	Belongs to the HesB IscA family
XJ27_RS01455	COG3115	cell septum assembly
XJ27_RS01460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XJ27_RS01465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XJ27_RS01470	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XJ27_RS01480	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XJ27_RS01510	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XJ27_RS01515	COG3178	'Phosphotransferase
XJ27_RS01525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XJ27_RS01530	COG1555	photosystem II stabilization
XJ27_RS01545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XJ27_RS01550	COG1477	protein flavinylation
XJ27_RS01575	COG3128	pkhd-type hydroxylase
XJ27_RS01580	COG4774	siderophore transport
XJ27_RS01595	COG0456	acetyltransferase
XJ27_RS01600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XJ27_RS01605	COG0719	Fe-S assembly protein
XJ27_RS01610	COG0396	ATPase activity
XJ27_RS01615	COG0719	Fe-S assembly protein
XJ27_RS01620	COG1959	2 iron, 2 sulfur cluster binding
XJ27_RS01645	COG4942	peptidase
XJ27_RS01660	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XJ27_RS01680	COG0519	Catalyzes the synthesis of GMP from XMP
XJ27_RS01685	COG1678	Uncharacterized ACR, COG1678
XJ27_RS01690	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XJ27_RS01700	COG1764	response to oxidative stress
XJ27_RS01710	COG0384	phenazine biosynthesis protein PhzF
XJ27_RS01715	COG0384	phenazine biosynthesis protein PhzF
XJ27_RS01720	COG0527	aspartate kinase activity
XJ27_RS01740	COG0142	geranyltranstransferase activity
XJ27_RS01745	COG0629	single-stranded DNA binding
XJ27_RS01760	COG4251	negative regulation of phosphorylation
XJ27_RS01760	COG5001	Diguanylate cyclase
XJ27_RS01760	COG2203	Gaf domain
XJ27_RS01760	COG3706	GGDEF domain
XJ27_RS01765	COG2080	2 iron, 2 sulfur cluster binding
XJ27_RS01770	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XJ27_RS01775	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XJ27_RS01780	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XJ27_RS01810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XJ27_RS01845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XJ27_RS01855	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XJ27_RS01865	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XJ27_RS01915	COG2244	polysaccharide biosynthetic process
XJ27_RS01945	COG2264	protein methyltransferase activity
XJ27_RS01950	COG0297	glycogen (starch) synthase activity
XJ27_RS01955	COG0438	transferase activity, transferring glycosyl groups
XJ27_RS01975	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XJ27_RS01980	COG1132	(ABC) transporter
XJ27_RS01990	COG0477	Major facilitator Superfamily
XJ27_RS01995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XJ27_RS02010	COG1253	flavin adenine dinucleotide binding
XJ27_RS02050	COG0504	CTP synthase activity
XJ27_RS02065	COG0148	phosphopyruvate hydratase activity
XJ27_RS02075	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XJ27_RS02080	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XJ27_RS02090	COG2840	Smr protein MutS2
XJ27_RS02095	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XJ27_RS02100	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XJ27_RS02105	COG1238	metal cluster binding
XJ27_RS02120	COG1534	Rna-binding protein
XJ27_RS02125	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XJ27_RS02135	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XJ27_RS02140	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XJ27_RS02150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XJ27_RS02155	COG1546	Belongs to the CinA family
XJ27_RS02160	COG4771	TonB-dependent receptor
XJ27_RS02165	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XJ27_RS02175	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XJ27_RS02180	COG2137	regulation of response to DNA damage stimulus
XJ27_RS02185	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XJ27_RS02190	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XJ27_RS02205	COG1741	Belongs to the pirin family
XJ27_RS02210	COG0583	DNA-binding transcription factor activity
XJ27_RS02230	COG0352	thiamine-phosphate diphosphorylase activity
XJ27_RS02230	COG0351	phosphomethylpyrimidine kinase
XJ27_RS02245	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XJ27_RS02250	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XJ27_RS02265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XJ27_RS02275	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XJ27_RS02295	COG4948	Mandelate Racemase Muconate Lactonizing
XJ27_RS02300	COG0800	Aldolase
XJ27_RS02335	COG1501	Belongs to the glycosyl hydrolase 31 family
XJ27_RS02345	COG1070	Carbohydrate kinase
XJ27_RS02350	COG2115	Belongs to the xylose isomerase family
XJ27_RS02355	COG0477	Major facilitator Superfamily
XJ27_RS02375	COG0860	N-Acetylmuramoyl-L-alanine amidase
XJ27_RS02395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XJ27_RS02400	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XJ27_RS02405	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XJ27_RS02410	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XJ27_RS02445	COG1472	Belongs to the glycosyl hydrolase 3 family
XJ27_RS02455	COG4251	negative regulation of phosphorylation
XJ27_RS02455	COG3706	GGDEF domain
XJ27_RS02455	COG2203	Gaf domain
XJ27_RS02455	COG5001	Diguanylate cyclase
XJ27_RS02460	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XJ27_RS02470	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XJ27_RS02480	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XJ27_RS02485	COG0671	phosphoesterase, PA-phosphatase related
XJ27_RS02500	COG0697	spore germination
XJ27_RS02505	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XJ27_RS02510	COG0167	dihydroorotate dehydrogenase activity
XJ27_RS02525	COG1012	belongs to the aldehyde dehydrogenase family
XJ27_RS02570	COG0210	DNA helicase
XJ27_RS02625	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
XJ27_RS02625	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
XJ27_RS02660	COG1215	transferase activity, transferring glycosyl groups
XJ27_RS02665	COG1649	PFAM Uncharacterised BCR, COG1649
XJ27_RS02665	COG0726	polysaccharide deacetylase
XJ27_RS02700	COG0527	aspartate kinase activity
XJ27_RS02700	COG0460	homoserine dehydrogenase
XJ27_RS02725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XJ27_RS02745	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XJ27_RS02750	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XJ27_RS02755	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XJ27_RS02760	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XJ27_RS02760	COG0131	Imidazoleglycerol-phosphate dehydratase
XJ27_RS02775	COG0107	imidazoleglycerol-phosphate synthase activity
XJ27_RS02780	COG0140	phosphoribosyl-ATP diphosphatase activity
XJ27_RS02780	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XJ27_RS02800	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XJ27_RS02825	COG0531	amino acid
XJ27_RS02830	COG0531	amino acid
XJ27_RS02845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XJ27_RS02850	COG0277	FAD linked oxidase domain protein
XJ27_RS02870	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XJ27_RS02885	COG1024	Enoyl-CoA hydratase
XJ27_RS02905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XJ27_RS02910	COG2258	MOSC domain
XJ27_RS02920	COG0505	Belongs to the CarA family
XJ27_RS02930	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XJ27_RS02935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XJ27_RS02945	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XJ27_RS02970	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XJ27_RS02975	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XJ27_RS02985	COG0784	Response regulator, receiver
XJ27_RS02985	COG2198	Histidine kinase
XJ27_RS02985	COG2205	protein histidine kinase activity
XJ27_RS02990	COG2198	Histidine kinase
XJ27_RS02990	COG2205	protein histidine kinase activity
XJ27_RS02990	COG0784	Response regulator, receiver
XJ27_RS03030	COG2267	carboxylic ester hydrolase activity
XJ27_RS03050	COG2201	protein-glutamate methylesterase activity
XJ27_RS03065	COG0840	transmembrane signaling receptor activity
XJ27_RS03075	COG0835	chemotaxis
XJ27_RS03095	COG0840	transmembrane signaling receptor activity
XJ27_RS03100	COG0840	transmembrane signaling receptor activity
XJ27_RS03105	COG0840	transmembrane signaling receptor activity
XJ27_RS03110	COG0840	transmembrane signaling receptor activity
XJ27_RS03115	COG0840	transmembrane signaling receptor activity
XJ27_RS03120	COG0840	transmembrane signaling receptor activity
XJ27_RS03125	COG0840	transmembrane signaling receptor activity
XJ27_RS03130	COG0840	transmembrane signaling receptor activity
XJ27_RS03130	COG0840	transmembrane signaling receptor activity
XJ27_RS03140	COG0840	transmembrane signaling receptor activity
XJ27_RS03150	COG2198	Histidine kinase
XJ27_RS03150	COG0643	Histidine kinase
XJ27_RS03155	COG0745	RESPONSE REGULATOR receiver
XJ27_RS03165	COG0835	chemotaxis
XJ27_RS03170	COG1192	Involved in chromosome partitioning
XJ27_RS03180	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XJ27_RS03200	COG2198	Histidine kinase
XJ27_RS03200	COG0784	Response regulator, receiver
XJ27_RS03200	COG0643	Histidine kinase
XJ27_RS03250	COG5001	Diguanylate cyclase
XJ27_RS03250	COG3300	MHYT domain
XJ27_RS03320	COG1677	Flagellar hook-basal body complex protein FliE
XJ27_RS03365	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS03370	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS03375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XJ27_RS03395	COG2201	protein-glutamate methylesterase activity
XJ27_RS03425	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XJ27_RS03430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XJ27_RS03445	COG1705	Flagellar rod assembly protein muramidase FlgJ
XJ27_RS03445	COG3951	Flagellar rod assembly protein muramidase FlgJ
XJ27_RS03465	COG4787	bacterial-type flagellum-dependent cell motility
XJ27_RS03475	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XJ27_RS03480	COG1558	bacterial-type flagellum-dependent cell motility
XJ27_RS03490	COG0784	Response regulator, receiver
XJ27_RS03490	COG0835	chemotaxis
XJ27_RS03510	COG4191	Histidine kinase
XJ27_RS03565	COG0482	sulfurtransferase activity
XJ27_RS03580	COG0542	response to heat
XJ27_RS03590	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XJ27_RS03600	COG0492	ferredoxin-NADP+ reductase activity
XJ27_RS03605	COG1674	ftsk spoiiie
XJ27_RS03620	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XJ27_RS03625	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XJ27_RS03630	COG0183	Belongs to the thiolase family
XJ27_RS03635	COG1250	3-hydroxyacyl-CoA dehydrogenase
XJ27_RS03635	COG1024	Enoyl-CoA hydratase
XJ27_RS03650	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XJ27_RS03670	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XJ27_RS03675	COG1160	GTP binding
XJ27_RS03680	COG0303	'Molybdopterin
XJ27_RS03685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XJ27_RS03695	COG0708	Exodeoxyribonuclease III
XJ27_RS03705	COG0303	'Molybdopterin
XJ27_RS03710	COG0746	molybdenum cofactor guanylyltransferase activity
XJ27_RS03720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XJ27_RS03720	COG1648	precorrin-2 dehydrogenase activity
XJ27_RS03730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XJ27_RS03745	COG2223	nitrite transmembrane transporter activity
XJ27_RS03750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XJ27_RS03760	COG0243	molybdopterin cofactor binding
XJ27_RS03780	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
XJ27_RS03790	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XJ27_RS03800	COG0579	oxidoreductase
XJ27_RS03810	COG3685	Protein conserved in bacteria
XJ27_RS03825	COG5001	Diguanylate cyclase
XJ27_RS03895	COG4191	Histidine kinase
XJ27_RS03895	COG0784	Response regulator, receiver
XJ27_RS03930	COG3781	membrane
XJ27_RS03935	COG4191	Histidine kinase
XJ27_RS03940	COG2197	response regulator
XJ27_RS03970	COG0840	transmembrane signaling receptor activity
XJ27_RS04135	COG2154	pterin-4-alpha-carbinolamine dehydratase
XJ27_RS04145	COG0428	transporter
XJ27_RS04160	COG3039	Transposase
XJ27_RS04220	COG0428	transporter
XJ27_RS04230	COG1530	ribonuclease E activity
XJ27_RS04240	COG1054	Belongs to the UPF0176 family
XJ27_RS04260	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XJ27_RS04360	COG0629	single-stranded DNA binding
XJ27_RS04365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XJ27_RS04370	COG0270	DNA (cytosine-5-)-methyltransferase activity
XJ27_RS04575	COG0583	DNA-binding transcription factor activity
XJ27_RS04580	COG0477	Major facilitator Superfamily
XJ27_RS04590	COG3039	Transposase
XJ27_RS04595	COG1960	acyl-CoA dehydrogenase activity
XJ27_RS04600	COG3039	Transposase
XJ27_RS04615	COG3039	Transposase
XJ27_RS04630	COG2816	NAD+ diphosphatase activity
XJ27_RS04640	COG2814	Major facilitator Superfamily
XJ27_RS04675	COG3830	Belongs to the UPF0237 family
XJ27_RS04675	COG0560	Phosphoserine phosphatase
XJ27_RS04685	COG4221	oxidoreductase activity
XJ27_RS04690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XJ27_RS04695	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS04850	COG0583	DNA-binding transcription factor activity
XJ27_RS04855	COG1396	sequence-specific DNA binding
XJ27_RS04865	COG0582	viral genome integration into host DNA
XJ27_RS04875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XJ27_RS04880	COG0322	excinuclease ABC activity
XJ27_RS04890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XJ27_RS04895	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XJ27_RS04905	COG1663	tetraacyldisaccharide 4'-kinase activity
XJ27_RS04910	COG1132	(ABC) transporter
XJ27_RS04920	COG0811	peptide transport
XJ27_RS04940	COG4591	ABC-type transport system involved in lipoprotein release permease component
XJ27_RS04950	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XJ27_RS04955	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XJ27_RS04970	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XJ27_RS04975	COG2009	succinate dehydrogenase
XJ27_RS04985	COG0354	folic acid binding
XJ27_RS04995	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XJ27_RS05000	COG0837	glucose binding
XJ27_RS05005	COG0363	glucosamine-6-phosphate deaminase activity
XJ27_RS05010	COG0129	dihydroxy-acid dehydratase activity
XJ27_RS05015	COG0800	Aldolase
XJ27_RS05110	COG0582	viral genome integration into host DNA
XJ27_RS05125	COG5002	protein histidine kinase activity
XJ27_RS05125	COG2205	protein histidine kinase activity
XJ27_RS05125	COG0784	Response regulator, receiver
XJ27_RS05135	COG2183	response to ionizing radiation
XJ27_RS05160	COG3243	poly(R)-hydroxyalkanoic acid synthase
XJ27_RS05170	COG1183	phosphatidylcholine synthase activity
XJ27_RS05175	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS05200	COG0668	transmembrane transport
XJ27_RS05205	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XJ27_RS05220	COG1914	H( )-stimulated, divalent metal cation uptake system
XJ27_RS05240	COG2801	Transposase and inactivated derivatives
XJ27_RS05250	COG3039	Transposase
XJ27_RS05295	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XJ27_RS05305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XJ27_RS05305	COG0475	glutathione-regulated potassium exporter activity
XJ27_RS05310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XJ27_RS05320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XJ27_RS05325	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XJ27_RS05335	COG0776	regulation of translation
XJ27_RS05360	COG2957	Belongs to the agmatine deiminase family
XJ27_RS05365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XJ27_RS05390	COG0395	ABC-type sugar transport system, permease component
XJ27_RS05395	COG1175	transmembrane transport
XJ27_RS05400	COG1653	transport
XJ27_RS05425	COG2350	Protein conserved in bacteria
XJ27_RS05430	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XJ27_RS05435	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XJ27_RS05440	COG1187	pseudouridine synthase activity
XJ27_RS05460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XJ27_RS05465	COG0436	Aminotransferase
XJ27_RS05490	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XJ27_RS05530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XJ27_RS05535	COG4988	ABC transporter
XJ27_RS05545	COG1294	oxidase, subunit
XJ27_RS05580	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XJ27_RS05595	COG0165	Argininosuccinate lyase
XJ27_RS05610	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XJ27_RS05615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XJ27_RS05620	COG0137	argininosuccinate synthase activity
XJ27_RS05625	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XJ27_RS05645	COG2166	iron-sulfur cluster assembly
XJ27_RS05665	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XJ27_RS05680	COG4303	Ethanolamine ammonia lyase large subunit
XJ27_RS05685	COG4302	ethanolamine ammonia-lyase activity
XJ27_RS05750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XJ27_RS05755	COG0402	S-adenosylhomocysteine deaminase activity
XJ27_RS05770	COG1509	lysine 2,3-aminomutase activity
XJ27_RS05775	COG3300	MHYT domain
XJ27_RS05775	COG5001	Diguanylate cyclase
XJ27_RS05790	COG0483	inositol monophosphate 1-phosphatase activity
XJ27_RS05795	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XJ27_RS05820	COG0628	permease
XJ27_RS05835	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XJ27_RS05860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XJ27_RS05865	COG0271	Belongs to the BolA IbaG family
XJ27_RS05875	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XJ27_RS05885	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XJ27_RS05890	COG1137	ATPase activity
XJ27_RS05905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XJ27_RS05925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XJ27_RS05930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XJ27_RS05935	COG2239	Acts as a magnesium transporter
XJ27_RS05945	COG1294	oxidase, subunit
XJ27_RS05950	COG1271	oxidase subunit
XJ27_RS05960	COG1113	amino acid transport
XJ27_RS05975	COG2197	response regulator
XJ27_RS05980	COG0531	amino acid
XJ27_RS06035	COG2814	Major facilitator Superfamily
XJ27_RS06040	COG0754	glutathionylspermidine amidase activity
XJ27_RS06065	COG1842	Phage shock protein A
XJ27_RS06080	COG0259	pyridoxamine-phosphate oxidase activity
XJ27_RS06085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XJ27_RS06090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XJ27_RS06100	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XJ27_RS06105	COG0488	(ABC) transporter
XJ27_RS06110	COG0513	Belongs to the DEAD box helicase family
XJ27_RS06115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XJ27_RS06120	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XJ27_RS06130	COG0625	glutathione transferase activity
XJ27_RS06140	COG1671	Belongs to the UPF0178 family
XJ27_RS06145	COG4681	YaeQ
XJ27_RS06150	COG2081	HI0933 family
XJ27_RS06155	COG5001	Diguanylate cyclase
XJ27_RS06155	COG3300	MHYT domain
XJ27_RS06165	COG0501	Belongs to the peptidase M48B family
XJ27_RS06170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XJ27_RS06175	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS06195	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XJ27_RS06200	COG0860	N-Acetylmuramoyl-L-alanine amidase
XJ27_RS06210	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XJ27_RS06210	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XJ27_RS06215	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XJ27_RS06235	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XJ27_RS06260	COG2199	diguanylate cyclase activity
XJ27_RS06265	COG0835	chemotaxis
XJ27_RS06270	COG0840	transmembrane signaling receptor activity
XJ27_RS06280	COG1201	RNA secondary structure unwinding
XJ27_RS06290	COG2969	positive regulation of protein catabolic process
XJ27_RS06295	COG0625	glutathione transferase activity
XJ27_RS06305	COG2857	Cytochrome c1
XJ27_RS06310	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XJ27_RS06315	COG0723	plastoquinol--plastocyanin reductase activity
XJ27_RS06320	COG0741	lytic transglycosylase activity
XJ27_RS06335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XJ27_RS06340	COG1702	phosphate starvation-inducible protein PhoH
XJ27_RS06360	COG4535	Mg2 and Co2 transporter CorC
XJ27_RS06380	COG1012	belongs to the aldehyde dehydrogenase family
XJ27_RS06390	COG1177	transmembrane transport
XJ27_RS06395	COG1176	ABC-type spermidine putrescine transport system, permease component I
XJ27_RS06405	COG3842	ATPase activity
XJ27_RS06440	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XJ27_RS06445	COG0174	glutamine synthetase
XJ27_RS06450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XJ27_RS06490	COG0243	molybdopterin cofactor binding
XJ27_RS06500	COG2223	nitrite transmembrane transporter activity
XJ27_RS06505	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XJ27_RS06515	COG2733	membrane
XJ27_RS06520	COG2205	protein histidine kinase activity
XJ27_RS06520	COG5002	protein histidine kinase activity
XJ27_RS06520	COG0784	Response regulator, receiver
XJ27_RS06530	COG0477	Major facilitator Superfamily
XJ27_RS06540	COG0604	alcohol dehydrogenase
XJ27_RS06545	COG0300	oxidoreductase activity
XJ27_RS06560	COG1902	pentaerythritol trinitrate reductase activity
XJ27_RS06570	COG0604	alcohol dehydrogenase
XJ27_RS06570	COG3321	synthase
XJ27_RS06605	COG2902	Dehydrogenase
XJ27_RS06615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XJ27_RS06620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XJ27_RS06625	COG1609	Transcriptional regulator
XJ27_RS06630	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XJ27_RS06630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XJ27_RS06635	COG1105	Belongs to the carbohydrate kinase PfkB family
XJ27_RS06640	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XJ27_RS06640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XJ27_RS06675	COG2963	transposase activity
XJ27_RS06710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XJ27_RS06720	COG1862	Preprotein translocase
XJ27_RS06730	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XJ27_RS06770	COG3291	Pkd domain containing protein
XJ27_RS06780	COG0405	Gamma-glutamyltransferase
XJ27_RS06785	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XJ27_RS06805	COG0742	ribosomal rna small subunit methyltransferase
XJ27_RS06915	COG0531	amino acid
XJ27_RS06930	COG0006	proline dipeptidase activity
XJ27_RS06940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XJ27_RS06955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XJ27_RS06960	COG3938	Belongs to the proline racemase family
XJ27_RS06970	COG0552	protein localization to endoplasmic reticulum
XJ27_RS06975	COG1194	a g-specific adenine glycosylase
XJ27_RS07010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XJ27_RS07030	COG3040	lipid binding
XJ27_RS07040	COG1960	acyl-CoA dehydrogenase activity
XJ27_RS07050	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XJ27_RS07075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XJ27_RS07080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XJ27_RS07085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XJ27_RS07110	COG0438	transferase activity, transferring glycosyl groups
XJ27_RS07120	COG0438	transferase activity, transferring glycosyl groups
XJ27_RS07125	COG0438	transferase activity, transferring glycosyl groups
XJ27_RS07175	COG0072	phenylalanine-tRNA ligase activity
XJ27_RS07175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XJ27_RS07180	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XJ27_RS07195	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XJ27_RS07200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XJ27_RS07245	COG3702	type iv secretory pathway
XJ27_RS07265	COG2948	multi-organism process
XJ27_RS07285	COG3505	Type IV secretory pathway VirD4
XJ27_RS07300	COG0556	nucleotide-excision repair
XJ27_RS07345	COG1611	Belongs to the LOG family
XJ27_RS07355	COG2095	MarC family integral membrane protein
XJ27_RS07360	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS07365	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XJ27_RS07405	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XJ27_RS07410	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XJ27_RS07415	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XJ27_RS07420	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XJ27_RS07425	COG0195	Participates in both transcription termination and antitermination
XJ27_RS07430	COG0779	Required for maturation of 30S ribosomal subunits
XJ27_RS07440	COG1007	ATP synthesis coupled electron transport
XJ27_RS07460	COG0839	Belongs to the complex I subunit 6 family
XJ27_RS07470	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XJ27_RS07480	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XJ27_RS07485	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XJ27_RS07490	COG0649	NAD binding
XJ27_RS07495	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XJ27_RS07505	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XJ27_RS07525	COG4221	oxidoreductase activity
XJ27_RS07560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XJ27_RS07570	COG0159	tryptophan synthase activity
XJ27_RS07580	COG0133	tryptophan synthase activity
XJ27_RS07590	COG0135	phosphoribosylanthranilate isomerase activity
XJ27_RS07595	COG0101	tRNA pseudouridine synthase activity
XJ27_RS07610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XJ27_RS07615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XJ27_RS07630	COG2890	protein-(glutamine-N5) methyltransferase activity
XJ27_RS07640	COG0688	phosphatidylethanolamine metabolic process
XJ27_RS07650	COG0433	COG0433 Predicted ATPase
XJ27_RS07660	COG0494	nUDIX hydrolase
XJ27_RS07690	COG1472	Belongs to the glycosyl hydrolase 3 family
XJ27_RS07710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XJ27_RS07740	COG0717	Belongs to the dCTP deaminase family
XJ27_RS07750	COG0489	protein tyrosine kinase activity
XJ27_RS07775	COG3590	peptidase
XJ27_RS07800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XJ27_RS07805	COG2311	Membrane
XJ27_RS07810	COG1047	Peptidyl-prolyl cis-trans
XJ27_RS07815	COG0791	NLP P60 protein
XJ27_RS07820	COG0791	NLP P60 protein
XJ27_RS07835	COG1301	dicarboxylic acid transport
XJ27_RS07840	COG1785	Belongs to the alkaline phosphatase family
XJ27_RS07845	COG0037	tRNA processing
XJ27_RS07850	COG1722	exodeoxyribonuclease VII activity
XJ27_RS07855	COG0142	geranyltranstransferase activity
XJ27_RS07860	COG4104	PAAR repeat-containing protein
XJ27_RS07870	COG0312	modulator of DNA gyrase
XJ27_RS07880	COG0312	modulator of DNA gyrase
XJ27_RS07890	COG3164	Protein of unknown function
XJ27_RS07915	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XJ27_RS07935	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XJ27_RS07950	COG0495	leucyl-tRNA aminoacylation
XJ27_RS07960	COG3118	belongs to the thioredoxin family
XJ27_RS07980	COG0415	Belongs to the DNA photolyase family
XJ27_RS07990	COG0305	Participates in initiation and elongation during chromosome replication
XJ27_RS08000	COG0367	asparagine synthase
XJ27_RS08015	COG1960	acyl-CoA dehydrogenase activity
XJ27_RS08030	COG0084	hydrolase, TatD family'
XJ27_RS08035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XJ27_RS08070	COG0288	reversible hydration of carbon dioxide
XJ27_RS08100	COG0386	Belongs to the glutathione peroxidase family
XJ27_RS08105	COG0339	signal peptide processing
XJ27_RS08165	COG2814	Major facilitator Superfamily
XJ27_RS08170	COG1566	PFAM secretion protein HlyD family protein
XJ27_RS08215	COG4774	siderophore transport
XJ27_RS08225	COG0367	asparagine synthase
XJ27_RS08230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XJ27_RS08235	COG1393	Belongs to the ArsC family
XJ27_RS08250	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XJ27_RS08295	COG0052	Belongs to the universal ribosomal protein uS2 family
XJ27_RS08300	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XJ27_RS08310	COG0528	UMP kinase activity
XJ27_RS08320	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XJ27_RS08325	COG0575	Belongs to the CDS family
XJ27_RS08330	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XJ27_RS08335	COG0750	zinc metalloprotease
XJ27_RS08350	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XJ27_RS08355	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XJ27_RS08360	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XJ27_RS08365	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XJ27_RS08380	COG0825	malonyl-CoA metabolic process
XJ27_RS08390	COG1981	membrane
XJ27_RS08420	COG1695	Transcriptional regulator
XJ27_RS08455	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XJ27_RS08475	COG2040	homocysteine
XJ27_RS08480	COG0833	amino acid
XJ27_RS08485	COG0346	lactoylglutathione lyase activity
XJ27_RS08490	COG1131	(ABC) transporter
XJ27_RS08505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XJ27_RS08505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XJ27_RS08515	COG2878	Part of a membrane complex involved in electron transport
XJ27_RS08530	COG1595	DNA-templated transcription, initiation
XJ27_RS08575	COG0251	oxidation-reduction process
XJ27_RS08585	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XJ27_RS08585	COG0392	lysyltransferase activity
XJ27_RS08620	COG2814	Major facilitator Superfamily
XJ27_RS08625	COG1902	pentaerythritol trinitrate reductase activity
XJ27_RS08640	COG2824	Alkylphosphonate utilization operon protein PhnA
XJ27_RS08650	COG1047	Peptidyl-prolyl cis-trans
XJ27_RS08690	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XJ27_RS08700	COG5487	UPF0391 membrane protein
XJ27_RS08705	COG1451	nucleotide metabolic process
XJ27_RS08725	COG0183	Belongs to the thiolase family
XJ27_RS08755	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XJ27_RS08755	COG1793	dna ligase
XJ27_RS08765	COG1793	dna ligase
XJ27_RS08770	COG1201	RNA secondary structure unwinding
XJ27_RS08780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XJ27_RS08785	COG1278	Cold shock
XJ27_RS08790	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XJ27_RS08795	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XJ27_RS08800	COG1472	Belongs to the glycosyl hydrolase 3 family
XJ27_RS08805	COG3046	protein related to deoxyribodipyrimidine photolyase
XJ27_RS08810	COG1233	COG1233 Phytoene dehydrogenase and related
XJ27_RS08815	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XJ27_RS08820	COG2954	triphosphatase activity
XJ27_RS08845	COG1381	Involved in DNA repair and RecF pathway recombination
XJ27_RS08850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XJ27_RS08875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XJ27_RS08890	COG1024	Enoyl-CoA hydratase
XJ27_RS08890	COG1250	3-hydroxyacyl-CoA dehydrogenase
XJ27_RS08900	COG0457	Tetratricopeptide repeat
XJ27_RS08940	COG1024	Enoyl-CoA hydratase
XJ27_RS08945	COG1960	acyl-CoA dehydrogenase activity
XJ27_RS08965	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XJ27_RS08970	COG3250	beta-galactosidase activity
XJ27_RS08975	COG4948	Mandelate Racemase Muconate Lactonizing
XJ27_RS08980	COG1301	dicarboxylic acid transport
XJ27_RS08985	COG0583	DNA-binding transcription factor activity
XJ27_RS09005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XJ27_RS09025	COG0840	transmembrane signaling receptor activity
XJ27_RS09035	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XJ27_RS09045	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XJ27_RS09060	COG0534	Mate efflux family protein
XJ27_RS09070	COG0336	Belongs to the RNA methyltransferase TrmD family
XJ27_RS09075	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XJ27_RS09100	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XJ27_RS09140	COG3534	alpha-L-arabinofuranosidase
XJ27_RS09165	COG0784	Response regulator, receiver
XJ27_RS09165	COG4191	Histidine kinase
XJ27_RS09170	COG2205	protein histidine kinase activity
XJ27_RS09170	COG3437	response regulator, receiver
XJ27_RS09170	COG3850	Histidine kinase
XJ27_RS09170	COG4999	Histidine kinase
XJ27_RS09175	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XJ27_RS09185	COG2205	protein histidine kinase activity
XJ27_RS09190	COG5507	3-demethylubiquinone-9 3-methyltransferase
XJ27_RS09200	COG4771	TonB-dependent receptor
XJ27_RS09225	COG2172	sigma factor antagonist activity
XJ27_RS09230	COG1366	Belongs to the anti-sigma-factor antagonist family
XJ27_RS09235	COG1366	Belongs to the anti-sigma-factor antagonist family
XJ27_RS09240	COG1902	pentaerythritol trinitrate reductase activity
XJ27_RS09255	COG0326	Molecular chaperone. Has ATPase activity
XJ27_RS09260	COG2207	Transcriptional regulator
XJ27_RS09270	COG3152	Membrane
XJ27_RS09285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XJ27_RS09290	COG1845	cytochrome c oxidase, subunit III
XJ27_RS09295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XJ27_RS09315	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XJ27_RS09325	COG0196	riboflavin kinase activity
XJ27_RS09340	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XJ27_RS09345	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XJ27_RS09355	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XJ27_RS09360	COG0824	Thioesterase
XJ27_RS09370	COG1024	Enoyl-CoA hydratase
XJ27_RS09375	COG1946	Acyl-CoA thioesterase
XJ27_RS09385	COG1595	DNA-templated transcription, initiation
XJ27_RS09405	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XJ27_RS09455	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XJ27_RS09470	COG2197	response regulator
XJ27_RS09475	COG4585	Histidine kinase
XJ27_RS09490	COG2894	cell division
XJ27_RS09495	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XJ27_RS09505	COG5002	protein histidine kinase activity
XJ27_RS09510	COG0745	RESPONSE REGULATOR receiver
XJ27_RS09525	COG2194	sulfuric ester hydrolase activity
XJ27_RS09550	COG2814	Major facilitator Superfamily
XJ27_RS09555	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XJ27_RS09555	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XJ27_RS09570	COG0656	L-ascorbic acid biosynthetic process
XJ27_RS09580	COG0753	catalase activity
XJ27_RS09590	COG1917	Cupin 2, conserved barrel domain protein
XJ27_RS09590	COG2207	Transcriptional regulator
XJ27_RS09600	COG1506	peptidase
XJ27_RS09600	COG0823	Involved in the tonB-independent uptake of proteins
XJ27_RS09610	COG1297	OPT oligopeptide transporter protein
XJ27_RS09625	COG0587	DNA-directed DNA polymerase activity
XJ27_RS09680	COG2080	2 iron, 2 sulfur cluster binding
XJ27_RS09685	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XJ27_RS09690	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XJ27_RS09740	COG3537	Alpha-1,2-mannosidase
XJ27_RS09750	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS09770	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XJ27_RS09805	COG3039	Transposase
XJ27_RS09855	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XJ27_RS09870	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
XJ27_RS09920	COG0330	HflC and HflK could
XJ27_RS09925	COG0330	HflC and HflK could
XJ27_RS09945	COG0678	peroxiredoxin activity
XJ27_RS09955	COG4953	penicillin-binding protein 1C
XJ27_RS09975	COG2373	Large extracellular alpha-helical protein
XJ27_RS10010	COG3829	transcription factor binding
XJ27_RS10020	COG2161	toxin-antitoxin pair type II binding
XJ27_RS10025	COG4115	mRNA cleavage
XJ27_RS10045	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XJ27_RS10050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XJ27_RS10070	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XJ27_RS10080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XJ27_RS10085	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XJ27_RS10090	COG1399	metal-binding, possibly nucleic acid-binding protein
XJ27_RS10095	COG0424	maF-like protein
XJ27_RS10110	COG0714	Associated with various cellular activities
XJ27_RS10130	COG0537	adenosine 5'-monophosphoramidase activity
XJ27_RS10140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XJ27_RS10160	COG0314	molybdopterin synthase activity
XJ27_RS10165	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XJ27_RS10170	COG0315	cyclic pyranopterin monophosphate synthase activity
XJ27_RS10175	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XJ27_RS10180	COG1234	tRNA 3'-trailer cleavage
XJ27_RS10190	COG0859	PFAM glycosyl transferase family 9
XJ27_RS10295	COG0631	protein serine/threonine phosphatase activity
XJ27_RS10300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XJ27_RS10315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XJ27_RS10325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XJ27_RS10355	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XJ27_RS10365	COG0544	peptidyl-prolyl cis-trans isomerase activity
XJ27_RS10415	COG4695	Portal protein
XJ27_RS10680	COG0473	3-isopropylmalate dehydrogenase activity
XJ27_RS10695	COG4783	chaperone-mediated protein folding
XJ27_RS10700	COG0745	RESPONSE REGULATOR receiver
XJ27_RS10710	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XJ27_RS10720	COG0438	transferase activity, transferring glycosyl groups
XJ27_RS10725	COG0671	phosphoesterase, PA-phosphatase related
XJ27_RS10730	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XJ27_RS10740	COG3291	Pkd domain containing protein
XJ27_RS10745	COG2833	Protein of unknown function (DUF455)
XJ27_RS10765	COG0285	dihydrofolate synthase activity
XJ27_RS10775	COG0406	alpha-ribazole phosphatase activity
XJ27_RS10795	COG1063	alcohol dehydrogenase
XJ27_RS10805	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XJ27_RS10810	COG4208	sulfate ABC transporter
XJ27_RS10815	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XJ27_RS10820	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XJ27_RS10825	COG0156	8-amino-7-oxononanoate synthase activity
XJ27_RS10845	COG2885	chlorophyll binding
XJ27_RS10850	COG0604	alcohol dehydrogenase
XJ27_RS10855	COG0446	pyridine nucleotide-disulphide oxidoreductase
XJ27_RS10855	COG1902	pentaerythritol trinitrate reductase activity
XJ27_RS10870	COG0625	glutathione transferase activity
XJ27_RS10880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XJ27_RS10885	COG1217	gtp-binding protein TYPA
XJ27_RS10895	COG0154	amidase activity
XJ27_RS10905	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XJ27_RS10920	COG0203	ribosomal protein L17
XJ27_RS10945	COG0201	protein transport
XJ27_RS10990	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XJ27_RS11000	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XJ27_RS11005	COG0255	Belongs to the universal ribosomal protein uL29 family
XJ27_RS11020	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XJ27_RS11030	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XJ27_RS11050	COG0051	transcription antitermination factor activity, RNA binding
XJ27_RS11055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XJ27_RS11070	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XJ27_RS11075	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XJ27_RS11085	COG0222	ribosome binding
XJ27_RS11090	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XJ27_RS11095	COG0081	regulation of translation
XJ27_RS11100	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XJ27_RS11105	COG0250	Participates in transcription elongation, termination and antitermination
XJ27_RS11140	COG0012	GTP binding
XJ27_RS11145	COG0193	aminoacyl-tRNA hydrolase activity
XJ27_RS11150	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XJ27_RS11155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XJ27_RS11170	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XJ27_RS11180	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XJ27_RS11205	COG0521	Mo-molybdopterin cofactor biosynthetic process
XJ27_RS11225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XJ27_RS11230	COG1295	ribonuclease BN
XJ27_RS11255	COG1404	Belongs to the peptidase S8 family
XJ27_RS11265	COG1404	Belongs to the peptidase S8 family
XJ27_RS11270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XJ27_RS11320	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XJ27_RS11320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XJ27_RS11335	COG2890	protein-(glutamine-N5) methyltransferase activity
XJ27_RS11345	COG3634	alkyl hydroperoxide reductase activity
XJ27_RS11350	COG0583	DNA-binding transcription factor activity
XJ27_RS11360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XJ27_RS11370	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XJ27_RS11380	COG2197	response regulator
XJ27_RS11385	COG5002	protein histidine kinase activity
XJ27_RS11385	COG0784	Response regulator, receiver
XJ27_RS11385	COG2205	protein histidine kinase activity
XJ27_RS11405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XJ27_RS11410	COG0697	spore germination
XJ27_RS11440	COG3386	PFAM SMP-30 Gluconolaconase
XJ27_RS11465	COG1024	Enoyl-CoA hydratase
XJ27_RS11475	COG0318	PFAM AMP-dependent synthetase and ligase
XJ27_RS11480	COG0583	DNA-binding transcription factor activity
XJ27_RS11485	COG3384	dioxygenase
XJ27_RS11515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XJ27_RS11520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XJ27_RS11530	COG2096	Adenosyltransferase
XJ27_RS11535	COG0123	including yeast histone deacetylase and acetoin utilization protein
XJ27_RS11540	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XJ27_RS11555	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XJ27_RS11560	COG2967	ApaG domain
XJ27_RS11565	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XJ27_RS11570	COG0431	NADPH-dependent FMN reductase
XJ27_RS11575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XJ27_RS11585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XJ27_RS11590	COG1116	anion transmembrane transporter activity
XJ27_RS11610	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XJ27_RS11630	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XJ27_RS11640	COG0642	Histidine kinase
XJ27_RS11655	COG4181	ATPase activity
XJ27_RS11665	COG2175	clavaminate synthase activity
XJ27_RS11675	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XJ27_RS11730	COG4771	TonB-dependent receptor
XJ27_RS11740	COG0667	Aldo Keto reductase
XJ27_RS11745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XJ27_RS11760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XJ27_RS11765	COG4106	trans-aconitate 2-methyltransferase activity
XJ27_RS11775	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XJ27_RS11785	COG2885	chlorophyll binding
XJ27_RS11805	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XJ27_RS11825	COG3039	Transposase
XJ27_RS11875	COG0604	alcohol dehydrogenase
XJ27_RS11875	COG3321	synthase
XJ27_RS11875	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS11885	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XJ27_RS11905	COG0494	nUDIX hydrolase
XJ27_RS11915	COG0653	protein targeting
XJ27_RS11920	COG0739	heme binding
XJ27_RS11945	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XJ27_RS11950	COG1181	Belongs to the D-alanine--D-alanine ligase family
XJ27_RS11955	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XJ27_RS11975	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XJ27_RS11980	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XJ27_RS11990	COG3116	cell division
XJ27_RS12035	COG0792	nuclease activity
XJ27_RS12040	COG1988	membrane-bound metal-dependent
XJ27_RS12045	COG0277	FAD linked oxidase domain protein
XJ27_RS12050	COG0745	RESPONSE REGULATOR receiver
XJ27_RS12055	COG2205	protein histidine kinase activity
XJ27_RS12065	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XJ27_RS12070	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XJ27_RS12090	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XJ27_RS12130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XJ27_RS12130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XJ27_RS12145	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XJ27_RS12155	COG0488	(ABC) transporter
XJ27_RS12160	COG0242	peptide deformylase activity
XJ27_RS12175	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XJ27_RS12220	COG2188	Transcriptional regulator
XJ27_RS12255	COG1450	Type ii and iii secretion system protein
XJ27_RS12270	COG3166	PFAM Fimbrial assembly family protein
XJ27_RS12275	COG3156	type II secretion system protein K
XJ27_RS12280	COG4795	General secretion pathway protein
XJ27_RS12285	COG2165	general secretion pathway protein
XJ27_RS12290	COG4970	Tfp pilus assembly protein FimT
XJ27_RS12295	COG2165	general secretion pathway protein
XJ27_RS12300	COG1459	type II secretion system
XJ27_RS12305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XJ27_RS12310	COG1404	Belongs to the peptidase S8 family
XJ27_RS12315	COG5295	Hep Hag repeat protein
XJ27_RS12320	COG1404	Belongs to the peptidase S8 family
XJ27_RS12330	COG0047	phosphoribosylformylglycinamidine synthase activity
XJ27_RS12330	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XJ27_RS12335	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XJ27_RS12340	COG4974	Belongs to the 'phage' integrase family
XJ27_RS12355	COG0795	lipopolysaccharide-transporting ATPase activity
XJ27_RS12375	COG0525	valine-tRNA ligase activity
XJ27_RS12405	COG1183	phosphatidylcholine synthase activity
XJ27_RS12415	COG0442	prolyl-tRNA aminoacylation
XJ27_RS12430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XJ27_RS12435	COG1127	ABC transporter
XJ27_RS12485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XJ27_RS12490	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XJ27_RS12490	COG0662	Cupin 2, conserved barrel domain protein
XJ27_RS12515	COG2086	electron transfer activity
XJ27_RS12535	COG0463	Glycosyl transferase, family 2
XJ27_RS12560	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XJ27_RS12600	COG0626	cystathionine gamma-synthase activity
XJ27_RS12630	COG0625	glutathione transferase activity
XJ27_RS12645	COG0513	Belongs to the DEAD box helicase family
XJ27_RS12655	COG4771	TonB-dependent receptor
XJ27_RS12660	COG0720	synthase
XJ27_RS12670	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XJ27_RS12675	COG1956	GAF domain-containing protein
XJ27_RS12685	COG2819	hydrolase of the alpha beta superfamily
XJ27_RS12695	COG0546	phosphoglycolate phosphatase activity
XJ27_RS12700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XJ27_RS12705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XJ27_RS12720	COG0339	signal peptide processing
XJ27_RS12765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XJ27_RS12770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XJ27_RS12780	COG1136	(ABC) transporter
XJ27_RS12790	COG0577	efflux transmembrane transporter activity
XJ27_RS12800	COG4191	Histidine kinase
XJ27_RS12815	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XJ27_RS12830	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XJ27_RS12855	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XJ27_RS12865	COG0356	it plays a direct role in the translocation of protons across the membrane
XJ27_RS12880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XJ27_RS12890	COG0508	dehydrogenase complex catalyzes the overall conversion of
XJ27_RS12920	COG2011	ABC-type metal ion transport system permease component
XJ27_RS12925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XJ27_RS12930	COG0697	spore germination
XJ27_RS12935	COG1666	GTP binding
XJ27_RS12955	COG1187	pseudouridine synthase activity
XJ27_RS12960	COG2813	Specifically methylates the guanine in position
XJ27_RS12985	COG0784	Response regulator, receiver
XJ27_RS12985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XJ27_RS12985	COG2198	Histidine kinase
XJ27_RS12985	COG2205	protein histidine kinase activity
XJ27_RS13005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XJ27_RS13010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XJ27_RS13125	COG0842	Transport permease protein
XJ27_RS13130	COG1131	(ABC) transporter
XJ27_RS13135	COG0025	NhaP-type Na H and K H
XJ27_RS13150	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XJ27_RS13155	COG1573	uracil-dna glycosylase
XJ27_RS13170	COG3384	dioxygenase
XJ27_RS13180	COG0583	DNA-binding transcription factor activity
XJ27_RS13190	COG0667	Aldo Keto reductase
XJ27_RS13200	COG3590	peptidase
XJ27_RS13225	COG0531	amino acid
XJ27_RS13240	COG2972	Histidine kinase
XJ27_RS13260	COG3685	Protein conserved in bacteria
XJ27_RS13265	COG3546	catalase activity
XJ27_RS13295	COG2204	response regulator
XJ27_RS13310	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS13320	COG3039	Transposase
XJ27_RS13330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XJ27_RS13350	COG1132	(ABC) transporter
XJ27_RS13365	COG1063	alcohol dehydrogenase
XJ27_RS13385	COG0583	DNA-binding transcription factor activity
XJ27_RS13390	COG2814	Major facilitator Superfamily
XJ27_RS13430	COG1131	(ABC) transporter
XJ27_RS13445	COG0251	oxidation-reduction process
XJ27_RS13475	COG0659	secondary active sulfate transmembrane transporter activity
XJ27_RS13485	COG0024	Methionine aminopeptidase
XJ27_RS13495	COG4977	sequence-specific DNA binding
XJ27_RS13510	COG1309	transcriptional regulator
XJ27_RS13515	COG0583	DNA-binding transcription factor activity
XJ27_RS13520	COG1902	pentaerythritol trinitrate reductase activity
XJ27_RS13540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XJ27_RS13545	COG1490	D-aminoacyl-tRNA deacylase activity
XJ27_RS13550	COG1560	Kdo2-lipid A biosynthetic process
XJ27_RS13595	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XJ27_RS13595	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XJ27_RS13600	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XJ27_RS13605	COG0242	peptide deformylase activity
XJ27_RS13610	COG1652	LysM domain
XJ27_RS13615	COG0758	DNA mediated transformation
XJ27_RS13635	COG1754	DNA topoisomerase type I activity
XJ27_RS13635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XJ27_RS13640	COG0009	L-threonylcarbamoyladenylate synthase
XJ27_RS13655	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS13665	COG0616	signal peptide processing
XJ27_RS13670	COG0534	Mate efflux family protein
XJ27_RS13685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XJ27_RS13695	COG0625	glutathione transferase activity
XJ27_RS13715	COG1252	NADH dehydrogenase
XJ27_RS13720	COG2860	membrane
XJ27_RS13725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XJ27_RS13730	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XJ27_RS13735	COG3437	response regulator, receiver
XJ27_RS13740	COG2177	Part of the ABC transporter FtsEX involved in
XJ27_RS13745	COG2884	Cell division ATP-binding protein ftsE
XJ27_RS13755	COG3118	belongs to the thioredoxin family
XJ27_RS13760	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XJ27_RS13780	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XJ27_RS13810	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XJ27_RS13810	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XJ27_RS13815	COG1473	amidohydrolase
XJ27_RS13820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XJ27_RS13825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XJ27_RS13840	COG4948	Mandelate Racemase Muconate Lactonizing
XJ27_RS13850	COG3023	N-Acetylmuramoyl-L-alanine amidase
XJ27_RS13855	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XJ27_RS13895	COG5383	Protein conserved in bacteria
XJ27_RS13910	COG0531	amino acid
XJ27_RS13925	COG4682	membrane
XJ27_RS13930	COG2133	pyrroloquinoline quinone binding
XJ27_RS13945	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XJ27_RS13960	COG1610	YqeY-like protein
XJ27_RS13965	COG1295	ribonuclease BN
XJ27_RS13970	COG0358	DNA primase activity
XJ27_RS13985	COG0109	protoheme IX farnesyltransferase activity
XJ27_RS14015	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XJ27_RS14030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XJ27_RS14075	COG0739	heme binding
XJ27_RS14090	COG2807	transmembrane transport
XJ27_RS14095	COG0708	Exodeoxyribonuclease III
XJ27_RS14110	COG1192	Involved in chromosome partitioning
XJ27_RS14115	COG1475	DNA binding
XJ27_RS14130	COG0463	Glycosyl transferase, family 2
XJ27_RS14150	COG0756	dUTP diphosphatase activity
XJ27_RS14155	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XJ27_RS14165	COG0018	arginyl-trna synthetase
XJ27_RS14175	COG4221	oxidoreductase activity
XJ27_RS14180	COG2755	lipolytic protein G-D-S-L family
XJ27_RS14180	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XJ27_RS14190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XJ27_RS14195	COG1166	arginine decarboxylase activity
XJ27_RS14230	COG2960	long-chain fatty acid transporting porin activity
XJ27_RS14235	COG0606	chelatase, subunit chli
XJ27_RS14255	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XJ27_RS14310	COG1090	epimerase
XJ27_RS14320	COG0642	Histidine kinase
XJ27_RS14340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XJ27_RS14365	COG1011	Hydrolase
XJ27_RS14370	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XJ27_RS14395	COG2197	response regulator
XJ27_RS14400	COG4585	Histidine kinase
XJ27_RS14405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XJ27_RS14410	COG1136	(ABC) transporter
XJ27_RS14435	COG0697	spore germination
XJ27_RS14470	COG0180	Tryptophanyl-tRNA synthetase
XJ27_RS14475	COG3237	CsbD-like
XJ27_RS14515	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XJ27_RS14530	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XJ27_RS14535	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XJ27_RS14535	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XJ27_RS14545	COG3228	Belongs to the MtfA family
XJ27_RS14575	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XJ27_RS14595	COG1199	ATP-dependent helicase activity
XJ27_RS14635	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XJ27_RS14675	COG0625	glutathione transferase activity
XJ27_RS14710	COG4555	ABC transporter
XJ27_RS14720	COG1476	TRANSCRIPTIONal
XJ27_RS14750	COG1131	(ABC) transporter
XJ27_RS14755	COG0842	Transport permease protein
XJ27_RS14765	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XJ27_RS14785	COG1607	acyl-coa hydrolase
XJ27_RS14800	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XJ27_RS14810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XJ27_RS14825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XJ27_RS14825	COG0045	succinate-CoA ligase (ADP-forming) activity
XJ27_RS14825	COG1042	CoA-binding domain protein
XJ27_RS14840	COG4771	TonB-dependent receptor
XJ27_RS14840	COG1629	transport
XJ27_RS14845	COG2239	Acts as a magnesium transporter
XJ27_RS14860	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XJ27_RS14865	COG3387	PFAM Glycoside hydrolase 15-related
XJ27_RS14880	COG3100	YcgL domain-containing protein
XJ27_RS14885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XJ27_RS14920	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS14950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XJ27_RS14965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XJ27_RS15010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XJ27_RS15010	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XJ27_RS15040	COG3621	Patatin-like phospholipase
XJ27_RS15065	COG0210	DNA helicase
XJ27_RS15080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XJ27_RS15090	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XJ27_RS15100	COG2159	amidohydrolase
XJ27_RS15120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XJ27_RS15150	COG3540	Alkaline phosphatase
XJ27_RS15160	COG2091	lysine biosynthetic process via aminoadipic acid
XJ27_RS15175	COG0708	Exodeoxyribonuclease III
XJ27_RS15190	COG1940	carbohydrate kinase activity
XJ27_RS15200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XJ27_RS15210	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XJ27_RS15215	COG3162	membrane
XJ27_RS15285	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS15290	COG0179	Fumarylacetoacetate (FAA) hydrolase
XJ27_RS15295	COG4948	Mandelate Racemase Muconate Lactonizing
XJ27_RS15300	COG3254	rhamnose metabolic process
XJ27_RS15305	COG0738	Major facilitator superfamily
XJ27_RS15310	COG1414	Transcriptional regulator
XJ27_RS15325	COG1971	Probably functions as a manganese efflux pump
XJ27_RS15330	COG2205	protein histidine kinase activity
XJ27_RS15340	COG3459	Glycosyltransferase 36 associated
XJ27_RS15345	COG2211	Major facilitator Superfamily
XJ27_RS15350	COG3265	gluconokinase activity
XJ27_RS15355	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XJ27_RS15390	COG2911	Protein conserved in bacteria
XJ27_RS15395	COG0729	surface antigen
XJ27_RS15410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XJ27_RS15425	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XJ27_RS15425	COG0519	Catalyzes the synthesis of GMP from XMP
XJ27_RS15435	COG0805	protein transport
XJ27_RS15440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XJ27_RS15445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XJ27_RS15455	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XJ27_RS15475	COG2974	May be involved in recombination
XJ27_RS15480	COG0037	tRNA processing
XJ27_RS15485	COG2115	Belongs to the xylose isomerase family
XJ27_RS15495	COG3661	Belongs to the glycosyl hydrolase 67 family
XJ27_RS15505	COG4948	Mandelate Racemase Muconate Lactonizing
XJ27_RS15515	COG1472	Belongs to the glycosyl hydrolase 3 family
XJ27_RS15520	COG0246	Mannitol dehydrogenase
XJ27_RS15545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XJ27_RS15550	COG1620	l-lactate permease
XJ27_RS15560	COG3386	PFAM SMP-30 Gluconolaconase
XJ27_RS15570	COG3250	beta-galactosidase activity
XJ27_RS15575	COG1904	glucuronate isomerase
XJ27_RS15580	COG3693	PFAM glycoside hydrolase, family 10
XJ27_RS15595	COG2211	Major facilitator Superfamily
XJ27_RS15640	COG2937	Belongs to the GPAT DAPAT family
XJ27_RS15665	COG0284	orotidine-5'-phosphate decarboxylase activity
XJ27_RS15670	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XJ27_RS15675	COG3132	Protein of unknown function, DUF480
XJ27_RS15695	COG0210	DNA helicase
XJ27_RS15700	COG1435	thymidine kinase activity
XJ27_RS15710	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XJ27_RS15720	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XJ27_RS15750	COG3135	benzoate transporter
XJ27_RS15770	COG0676	glucose-6-phosphate 1-epimerase activity
XJ27_RS15785	COG0730	response to heat
XJ27_RS15815	COG0302	gtp cyclohydrolase
XJ27_RS15830	COG1566	PFAM secretion protein HlyD family protein
XJ27_RS15840	COG1289	transmembrane transporter activity
XJ27_RS15845	COG0477	Major facilitator Superfamily
XJ27_RS15850	COG0583	DNA-binding transcription factor activity
XJ27_RS15855	COG4221	oxidoreductase activity
XJ27_RS15865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XJ27_RS15885	COG3293	Transposase
XJ27_RS15895	COG1192	Involved in chromosome partitioning
XJ27_RS15910	COG3550	peptidyl-serine autophosphorylation
XJ27_RS15945	COG3039	Transposase
XJ27_RS16000	COG2207	Transcriptional regulator
XJ27_RS16005	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS16015	COG3549	Plasmid maintenance system killer
XJ27_RS16030	COG1074	ATP-dependent DNA helicase activity
XJ27_RS16035	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XJ27_RS16040	COG1127	ABC transporter
XJ27_RS16045	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XJ27_RS16050	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XJ27_RS16065	COG2853	Lipoprotein
XJ27_RS16090	COG0386	Belongs to the glutathione peroxidase family
XJ27_RS16100	COG1322	Protein conserved in bacteria
XJ27_RS16105	COG0625	glutathione transferase activity
XJ27_RS16110	COG0531	amino acid
XJ27_RS16115	COG3537	Alpha-1,2-mannosidase
XJ27_RS16130	COG2199	diguanylate cyclase activity
XJ27_RS16130	COG2203	Gaf domain
XJ27_RS16135	COG3835	regulator
XJ27_RS16140	COG1929	Belongs to the glycerate kinase type-1 family
XJ27_RS16145	COG2271	Major facilitator Superfamily
XJ27_RS16180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XJ27_RS16185	COG1126	abc transporter atp-binding protein
XJ27_RS16195	COG1473	amidohydrolase
XJ27_RS16200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XJ27_RS16205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XJ27_RS16215	COG3039	Transposase
XJ27_RS16220	COG4206	TonB-dependent receptor
XJ27_RS16240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XJ27_RS16250	COG0861	Integral membrane protein TerC family
XJ27_RS16270	COG0584	glycerophosphoryl diester phosphodiesterase
XJ27_RS16295	COG0706	membrane insertase activity
XJ27_RS16330	COG0187	DNA topoisomerase II activity
XJ27_RS16340	COG0501	Belongs to the peptidase M48B family
XJ27_RS16375	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XJ27_RS16385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XJ27_RS16415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XJ27_RS16420	COG0793	Belongs to the peptidase S41A family
XJ27_RS16425	COG4942	peptidase
XJ27_RS16435	COG2234	aminopeptidase activity
XJ27_RS16445	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XJ27_RS16450	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XJ27_RS16455	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XJ27_RS16460	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XJ27_RS16465	COG1064	alcohol dehydrogenase
XJ27_RS16475	COG0493	'glutamate synthase
XJ27_RS16480	COG0067	glutamate synthase
XJ27_RS16480	COG0069	glutamate synthase activity
XJ27_RS16480	COG0070	glutamate synthase
XJ27_RS16515	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XJ27_RS16555	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS16635	COG1205	dead DEAH box helicase
XJ27_RS16635	COG1111	helicase
XJ27_RS16645	COG1272	protein, Hemolysin III
XJ27_RS16670	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS16690	COG0583	DNA-binding transcription factor activity
XJ27_RS16695	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS16710	COG2249	NAD(P)H dehydrogenase (quinone) activity
XJ27_RS16725	COG1733	regulation of RNA biosynthetic process
XJ27_RS16730	COG3039	Transposase
XJ27_RS16775	COG3237	CsbD-like
XJ27_RS16815	COG2816	NAD+ diphosphatase activity
XJ27_RS16820	COG0657	acetylesterase activity
XJ27_RS16830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XJ27_RS16880	COG0714	Associated with various cellular activities
XJ27_RS16935	COG4772	TonB-dependent receptor
XJ27_RS16945	COG0662	Cupin 2, conserved barrel domain protein
XJ27_RS16955	COG1012	belongs to the aldehyde dehydrogenase family
XJ27_RS17005	COG1755	Isoprenylcysteine carboxyl methyltransferase
XJ27_RS17015	COG2197	response regulator
XJ27_RS17030	COG3710	Transcriptional regulator
XJ27_RS17035	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XJ27_RS17045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XJ27_RS17050	COG4771	TonB-dependent receptor
XJ27_RS17195	COG0366	Alpha amylase catalytic
XJ27_RS17200	COG0366	Alpha amylase catalytic
XJ27_RS17205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XJ27_RS17235	COG2755	lipolytic protein G-D-S-L family
XJ27_RS17245	COG2755	lipolytic protein G-D-S-L family
XJ27_RS17245	COG0657	acetylesterase activity
XJ27_RS17255	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XJ27_RS17270	COG3507	Belongs to the glycosyl hydrolase 43 family
XJ27_RS17275	COG1609	Transcriptional regulator
XJ27_RS17285	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XJ27_RS17290	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS17300	COG2755	lipolytic protein G-D-S-L family
XJ27_RS17320	COG3186	Phenylalanine-4-hydroxylase
XJ27_RS17325	COG1522	sequence-specific DNA binding
XJ27_RS17335	COG1752	Esterase of the alpha-beta hydrolase superfamily
XJ27_RS17340	COG1119	ATPase activity
XJ27_RS17355	COG1125	glycine betaine transport
XJ27_RS17355	COG0517	IMP dehydrogenase activity
XJ27_RS17370	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XJ27_RS17380	COG3550	peptidyl-serine autophosphorylation
XJ27_RS17385	COG1396	sequence-specific DNA binding
XJ27_RS17415	COG0489	protein tyrosine kinase activity
XJ27_RS17420	COG2062	phosphohistidine phosphatase, SixA
XJ27_RS17430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XJ27_RS17460	COG1881	PFAM PEBP family protein
XJ27_RS17475	COG0174	glutamine synthetase
XJ27_RS17480	COG0347	Belongs to the P(II) protein family
XJ27_RS17485	COG0004	ammonium transporteR
XJ27_RS17490	COG3852	Histidine kinase
XJ27_RS17495	COG2204	response regulator
XJ27_RS17500	COG2032	superoxide dismutase activity
XJ27_RS17505	COG2032	superoxide dismutase activity
XJ27_RS17515	COG0183	Belongs to the thiolase family
XJ27_RS17560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XJ27_RS17570	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XJ27_RS17580	COG0028	Belongs to the TPP enzyme family
XJ27_RS17610	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XJ27_RS17625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XJ27_RS17630	COG3177	Filamentation induced by cAMP protein fic
XJ27_RS17635	COG0596	Alpha beta hydrolase
XJ27_RS17640	COG0727	PFAM Uncharacterised protein family (UPF0153)
XJ27_RS17645	COG0318	PFAM AMP-dependent synthetase and ligase
XJ27_RS17665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XJ27_RS17675	COG1181	Belongs to the D-alanine--D-alanine ligase family
XJ27_RS17690	COG0564	pseudouridine synthase activity
XJ27_RS17710	COG1446	asparaginase
XJ27_RS17715	COG0339	signal peptide processing
XJ27_RS17735	COG0583	DNA-binding transcription factor activity
XJ27_RS17740	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XJ27_RS17745	COG2224	Isocitrate lyase
XJ27_RS17775	COG4770	biotin carboxylase activity
XJ27_RS17780	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XJ27_RS17785	COG1960	acyl-CoA dehydrogenase activity
XJ27_RS17840	COG0523	cobalamin synthesis protein
XJ27_RS17855	COG0697	spore germination
XJ27_RS17865	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XJ27_RS17880	COG1846	Transcriptional regulator
XJ27_RS17885	COG1764	response to oxidative stress
XJ27_RS17910	COG0656	L-ascorbic acid biosynthetic process
XJ27_RS17915	COG2130	NADP-dependent
XJ27_RS17930	COG1187	pseudouridine synthase activity
XJ27_RS17945	COG1643	Atp-dependent helicase
XJ27_RS17950	COG0840	transmembrane signaling receptor activity
XJ27_RS17960	COG4807	Protein conserved in bacteria
XJ27_RS17965	COG2351	hydroxyisourate hydrolase activity
XJ27_RS17970	COG2072	flavoprotein involved in K transport
XJ27_RS17990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XJ27_RS18015	COG0596	Alpha beta hydrolase
XJ27_RS18090	COG2252	PERMEase
XJ27_RS18110	COG0084	hydrolase, TatD family'
XJ27_RS18125	COG0583	DNA-binding transcription factor activity
XJ27_RS18130	COG2814	Major facilitator Superfamily
XJ27_RS18160	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XJ27_RS18165	COG1902	pentaerythritol trinitrate reductase activity
XJ27_RS18200	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XJ27_RS18205	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XJ27_RS18210	COG0583	DNA-binding transcription factor activity
XJ27_RS18240	COG0702	epimerase
XJ27_RS18245	COG1733	regulation of RNA biosynthetic process
XJ27_RS18330	COG0129	dihydroxy-acid dehydratase activity
XJ27_RS18340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XJ27_RS18395	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XJ27_RS18400	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XJ27_RS18430	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XJ27_RS18435	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XJ27_RS18445	COG3485	protocatechuate 3,4-dioxygenase
XJ27_RS18460	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XJ27_RS18465	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XJ27_RS18475	COG1414	Transcriptional regulator
XJ27_RS18485	COG0657	acetylesterase activity
XJ27_RS18495	COG0445	tRNA wobble uridine modification
XJ27_RS18505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XJ27_RS18545	COG0156	8-amino-7-oxononanoate synthase activity
XJ27_RS18550	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XJ27_RS18555	COG1040	competence protein
XJ27_RS18610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XJ27_RS18610	COG2111	Na H antiporter
XJ27_RS18615	COG1006	Multisubunit Na H antiporter MnhC subunit
XJ27_RS18620	COG0651	ATP synthesis coupled electron transport
XJ27_RS18630	COG2212	antiporter activity
XJ27_RS18635	COG1320	monovalent cation:proton antiporter activity
XJ27_RS18655	COG2852	Protein conserved in bacteria
XJ27_RS18675	COG3104	oligopeptide transport
XJ27_RS18690	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XJ27_RS18705	COG0508	dehydrogenase complex catalyzes the overall conversion of
XJ27_RS18715	COG0513	Belongs to the DEAD box helicase family
XJ27_RS18725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XJ27_RS18765	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS18770	COG0702	epimerase
XJ27_RS18795	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XJ27_RS18800	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XJ27_RS18805	COG0297	glycogen (starch) synthase activity
XJ27_RS18815	COG1649	PFAM Uncharacterised BCR, COG1649
XJ27_RS18820	COG2354	Protein conserved in bacteria
XJ27_RS18825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XJ27_RS18830	COG1368	sulfuric ester hydrolase activity
XJ27_RS18840	COG3264	Mechanosensitive ion channel
XJ27_RS18840	COG1511	domain protein
XJ27_RS18860	COG3590	peptidase
XJ27_RS18895	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XJ27_RS18915	COG1597	lipid kinase activity
XJ27_RS18940	COG2826	transposase and inactivated derivatives, IS30 family
XJ27_RS18950	COG2267	carboxylic ester hydrolase activity
XJ27_RS19025	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XJ27_RS19095	COG0840	transmembrane signaling receptor activity
XJ27_RS19110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XJ27_RS19115	COG0134	indole-3-glycerol-phosphate synthase activity
XJ27_RS19125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XJ27_RS19140	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XJ27_RS19205	COG0316	Belongs to the HesB IscA family
XJ27_RS19215	COG2816	NAD+ diphosphatase activity
XJ27_RS19220	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XJ27_RS19240	COG2814	Major facilitator Superfamily
XJ27_RS19245	COG1289	transmembrane transporter activity
XJ27_RS19250	COG0151	Belongs to the GarS family
XJ27_RS19255	COG0138	bifunctional purine biosynthesis protein purh
XJ27_RS19280	COG3039	Transposase
XJ27_RS19295	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XJ27_RS19320	COG2264	protein methyltransferase activity
XJ27_RS19370	COG0210	DNA helicase
XJ27_RS19380	COG0439	Biotin carboxylase
XJ27_RS19390	COG0511	ligase activity, forming carbon-carbon bonds
XJ27_RS19395	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XJ27_RS19410	COG1324	tolerance protein
XJ27_RS19420	COG2356	endonuclease I
XJ27_RS19465	COG3039	Transposase
XJ27_RS19480	COG3550	peptidyl-serine autophosphorylation
XJ27_RS19485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XJ27_RS19515	COG3712	iron ion homeostasis
XJ27_RS19545	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XJ27_RS19550	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XJ27_RS19575	COG2353	YceI-like domain
XJ27_RS19600	COG3052	prosthetic group binding
XJ27_RS19635	COG1802	Transcriptional regulator
XJ27_RS19695	COG2826	transposase and inactivated derivatives, IS30 family
XJ27_RS19730	COG0210	DNA helicase
XJ27_RS19825	COG1506	peptidase
XJ27_RS19825	COG0823	Involved in the tonB-independent uptake of proteins
XJ27_RS19855	COG0435	Glutathione S-transferase
XJ27_RS19890	COG1506	peptidase
XJ27_RS19890	COG0823	Involved in the tonB-independent uptake of proteins
XJ27_RS19925	COG0697	spore germination
XJ27_RS19945	COG1113	amino acid transport
XJ27_RS19960	COG3507	Belongs to the glycosyl hydrolase 43 family
XJ27_RS20030	COG0840	transmembrane signaling receptor activity
XJ27_RS20035	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XJ27_RS20035	COG5297	Belongs to the glycosyl hydrolase family 6
XJ27_RS20040	COG0659	secondary active sulfate transmembrane transporter activity
XJ27_RS20080	COG3275	phosphorelay sensor kinase activity
XJ27_RS20090	COG0181	hydroxymethylbilane synthase activity
XJ27_RS20115	COG1505	serine-type exopeptidase activity
XJ27_RS20130	COG0436	Aminotransferase
XJ27_RS20145	COG2832	Protein of unknown function (DUF454)
XJ27_RS20155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XJ27_RS20165	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XJ27_RS20170	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XJ27_RS20175	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XJ27_RS20180	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XJ27_RS20215	COG2226	methyltransferase
XJ27_RS20220	COG5001	Diguanylate cyclase
XJ27_RS20220	COG3300	MHYT domain
XJ27_RS20225	COG0308	aminopeptidase N
XJ27_RS20280	COG3284	Transcriptional regulator
XJ27_RS20285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XJ27_RS20290	COG1077	Cell shape determining protein MreB Mrl
XJ27_RS20295	COG1792	Involved in formation and maintenance of cell shape
XJ27_RS20300	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
XJ27_RS20310	COG0772	Belongs to the SEDS family
XJ27_RS20320	COG2951	lytic endotransglycosylase activity
XJ27_RS20325	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XJ27_RS20330	COG1686	Belongs to the peptidase S11 family
XJ27_RS20345	COG0321	lipoyl(octanoyl) transferase activity
XJ27_RS20350	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XJ27_RS20370	COG1051	belongs to the nudix hydrolase family
XJ27_RS20370	COG1056	cytidyltransferase-related domain
XJ27_RS20405	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XJ27_RS20410	COG0673	inositol 2-dehydrogenase activity
XJ27_RS20415	COG2823	Periplasmic or secreted lipoprotein
XJ27_RS20420	COG4251	negative regulation of phosphorylation
XJ27_RS20425	COG0784	Response regulator, receiver
XJ27_RS20430	COG4191	Histidine kinase
XJ27_RS20435	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XJ27_RS20440	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS20490	COG1459	type II secretion system
XJ27_RS20515	COG3156	type II secretion system protein K
XJ27_RS20540	COG3250	beta-galactosidase activity
XJ27_RS20555	COG2188	Transcriptional regulator
XJ27_RS20565	COG1609	Transcriptional regulator
XJ27_RS20570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XJ27_RS20575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XJ27_RS20610	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XJ27_RS20620	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XJ27_RS20630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XJ27_RS20645	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XJ27_RS20655	COG2205	protein histidine kinase activity
XJ27_RS20690	COG3791	Glutathione-dependent formaldehyde-activating
XJ27_RS20700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XJ27_RS20710	COG0697	spore germination
XJ27_RS20760	COG0402	S-adenosylhomocysteine deaminase activity
XJ27_RS20775	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XJ27_RS20780	COG0726	polysaccharide deacetylase
XJ27_RS20785	COG4773	Receptor
XJ27_RS20880	COG2211	Major facilitator Superfamily
XJ27_RS20885	COG1609	Transcriptional regulator
XJ27_RS20890	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS20895	COG2851	Citrate transporter
XJ27_RS20910	COG0642	Histidine kinase
XJ27_RS20920	COG2197	response regulator
XJ27_RS20935	COG4191	Histidine kinase
XJ27_RS20950	COG0281	malic enzyme
XJ27_RS20950	COG0280	phosphate acetyltransferase
XJ27_RS20975	COG1560	Kdo2-lipid A biosynthetic process
XJ27_RS20980	COG1519	Transferase
XJ27_RS20990	COG1538	Outer membrane efflux protein
XJ27_RS20995	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XJ27_RS21015	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XJ27_RS21020	COG0066	3-isopropylmalate dehydratase activity
XJ27_RS21025	COG2226	methyltransferase
XJ27_RS21030	COG0473	3-isopropylmalate dehydrogenase activity
XJ27_RS21040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XJ27_RS21060	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XJ27_RS21065	COG0405	Gamma-glutamyltransferase
XJ27_RS21070	COG0840	transmembrane signaling receptor activity
XJ27_RS21075	COG0823	Involved in the tonB-independent uptake of proteins
XJ27_RS21075	COG4946	Tricorn protease homolog
XJ27_RS21075	COG1506	peptidase
XJ27_RS21085	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XJ27_RS21090	COG3710	Transcriptional regulator
XJ27_RS21110	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XJ27_RS21120	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XJ27_RS21140	COG0563	adenylate kinase activity
XJ27_RS21145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XJ27_RS21155	COG3781	membrane
XJ27_RS21165	COG0671	phosphoesterase, PA-phosphatase related
XJ27_RS21175	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS21200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XJ27_RS21205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XJ27_RS21235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XJ27_RS21240	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
XJ27_RS21250	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XJ27_RS21270	COG0352	thiamine-phosphate diphosphorylase activity
XJ27_RS21275	COG1773	rubredoxin
XJ27_RS21280	COG2912	Transglutaminase-like superfamily
XJ27_RS21300	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XJ27_RS21325	COG0006	proline dipeptidase activity
XJ27_RS21330	COG0006	proline dipeptidase activity
XJ27_RS21345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XJ27_RS21355	COG0346	lactoylglutathione lyase activity
XJ27_RS21360	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XJ27_RS21365	COG1561	YicC-like family, N-terminal region
XJ27_RS21380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XJ27_RS21390	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XJ27_RS21415	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XJ27_RS21445	COG0714	Associated with various cellular activities
XJ27_RS21480	COG1301	dicarboxylic acid transport
XJ27_RS21495	COG4773	Receptor
XJ27_RS21500	COG0583	DNA-binding transcription factor activity
XJ27_RS21505	COG1028	Short-chain dehydrogenase reductase Sdr
XJ27_RS21520	COG1376	ErfK ybiS ycfS ynhG family protein
XJ27_RS21540	COG3682	Transcriptional regulator
XJ27_RS21555	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XJ27_RS21560	COG4149	molybdate abc transporter
XJ27_RS21565	COG0725	ABC transporter, periplasmic molybdate-binding protein
XJ27_RS21570	COG3453	Protein conserved in bacteria
XJ27_RS21570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XJ27_RS21580	COG3047	cAMP biosynthetic process
XJ27_RS21595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XJ27_RS21625	COG0469	pyruvate kinase activity
XJ27_RS21635	COG3588	fructose-bisphosphate aldolase
XJ27_RS21640	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XJ27_RS21655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XJ27_RS21655	COG1648	precorrin-2 dehydrogenase activity
XJ27_RS21680	COG2198	Histidine kinase
XJ27_RS21680	COG0784	Response regulator, receiver
XJ27_RS21680	COG2205	protein histidine kinase activity
XJ27_RS21700	COG0175	sulfate reduction
XJ27_RS21705	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XJ27_RS21720	COG2895	sulfate adenylyltransferase (ATP) activity
XJ27_RS21720	COG0529	Catalyzes the synthesis of activated sulfate
XJ27_RS21725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XJ27_RS21730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XJ27_RS21750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XJ27_RS21755	COG2272	Belongs to the type-B carboxylesterase lipase family
XJ27_RS21765	COG4948	Mandelate Racemase Muconate Lactonizing
XJ27_RS21770	COG3250	beta-galactosidase activity
XJ27_RS21780	COG1609	Transcriptional regulator
XJ27_RS21810	COG0471	metal ion transport
XJ27_RS21810	COG3273	potassium ion transport
XJ27_RS21815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XJ27_RS21880	COG1238	metal cluster binding
XJ27_RS21885	COG0840	transmembrane signaling receptor activity
XJ27_RS21920	COG0189	ligase activity
XJ27_RS21925	COG0745	RESPONSE REGULATOR receiver
XJ27_RS21960	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XJ27_RS21995	COG0045	succinate-CoA ligase (ADP-forming) activity
XJ27_RS22000	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XJ27_RS22030	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XJ27_RS22030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XJ27_RS22040	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XJ27_RS22045	COG0564	pseudouridine synthase activity
XJ27_RS22060	COG3011	Protein conserved in bacteria
XJ27_RS22065	COG0840	transmembrane signaling receptor activity
XJ27_RS22080	COG3387	PFAM Glycoside hydrolase 15-related
XJ27_RS22085	COG1877	trehalose-phosphatase activity
XJ27_RS22135	COG4771	TonB-dependent receptor
XJ27_RS22145	COG0667	Aldo Keto reductase
XJ27_RS22150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XJ27_RS22155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XJ27_RS22160	COG1116	anion transmembrane transporter activity
XJ27_RS22165	COG0542	response to heat
XJ27_RS22175	COG4206	TonB-dependent receptor
XJ27_RS22180	COG1492	cobalamin metabolic process
XJ27_RS22190	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XJ27_RS22205	COG0019	diaminopimelate decarboxylase activity
XJ27_RS22210	COG4264	IucA IucC family
XJ27_RS22220	COG4264	IucA IucC family
XJ27_RS22230	COG4772	TonB-dependent receptor
XJ27_RS22240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XJ27_RS22240	COG4651	solute:proton antiporter activity
XJ27_RS22270	COG0488	(ABC) transporter
XJ27_RS22315	COG0477	Major facilitator Superfamily
XJ27_RS22335	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XJ27_RS22380	COG2255	four-way junction helicase activity
XJ27_RS22385	COG0824	Thioesterase
XJ27_RS22395	COG0848	biopolymer transport protein
XJ27_RS22410	COG2885	chlorophyll binding
XJ27_RS22420	COG0602	queuosine metabolic process
XJ27_RS22425	COG0667	Aldo Keto reductase
XJ27_RS22465	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XJ27_RS22470	COG3920	Histidine kinase
XJ27_RS22505	COG1187	pseudouridine synthase activity
XJ27_RS22525	COG0514	ATP-dependent DNA helicase (RecQ)
XJ27_RS22530	COG0783	Belongs to the Dps family
XJ27_RS22535	COG1643	Atp-dependent helicase
XJ27_RS22545	COG0837	glucose binding
XJ27_RS22565	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XJ27_RS22570	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XJ27_RS22580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XJ27_RS22595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XJ27_RS22605	COG1199	ATP-dependent helicase activity
XJ27_RS22625	COG0189	ligase activity
XJ27_RS22640	COG0835	chemotaxis
XJ27_RS22645	COG0840	transmembrane signaling receptor activity
XJ27_RS22650	COG2198	Histidine kinase
XJ27_RS22650	COG0784	Response regulator, receiver
XJ27_RS22650	COG0643	Histidine kinase
XJ27_RS22655	COG2201	protein-glutamate methylesterase activity
XJ27_RS22685	COG1595	DNA-templated transcription, initiation
XJ27_RS22690	COG2304	oxidoreductase activity
XJ27_RS22695	COG1446	asparaginase
XJ27_RS22700	COG3142	Participates in the control of copper homeostasis
XJ27_RS22775	COG3039	Transposase
XJ27_RS22800	COG3537	Alpha-1,2-mannosidase
XJ27_RS22810	COG1486	melibiose metabolic process
XJ27_RS22820	COG0531	amino acid
XJ27_RS22845	COG1472	Belongs to the glycosyl hydrolase 3 family
XJ27_RS22865	COG1388	LysM domain
XJ27_RS22865	COG3858	chitin binding
XJ27_RS22880	COG0837	glucose binding
XJ27_RS22885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XJ27_RS22895	COG0494	nUDIX hydrolase
XJ27_RS22900	COG1218	3'(2'),5'-bisphosphate nucleotidase
XJ27_RS22905	COG3956	TIGRFAM MazG family protein
XJ27_RS22910	COG1742	UPF0060 membrane protein
XJ27_RS22915	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XJ27_RS22920	COG0509	glycine decarboxylation via glycine cleavage system
XJ27_RS22955	COG1960	acyl-CoA dehydrogenase activity
XJ27_RS22965	COG1309	transcriptional regulator
XJ27_RS22970	COG4206	TonB-dependent receptor
XJ27_RS22980	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XJ27_RS22985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XJ27_RS22990	COG0463	Glycosyl transferase, family 2
XJ27_RS22995	COG0516	GMP reductase activity
XJ27_RS22995	COG0517	IMP dehydrogenase activity
XJ27_RS23005	COG2982	Protein involved in outer membrane biogenesis
XJ27_RS23010	COG1272	protein, Hemolysin III
XJ27_RS23015	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XJ27_RS23025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XJ27_RS23030	COG0626	cystathionine gamma-synthase activity
XJ27_RS23035	COG0460	homoserine dehydrogenase
XJ27_RS23035	COG0527	aspartate kinase activity
XJ27_RS23045	COG1760	l-serine dehydratase
XJ27_RS23060	COG1278	Cold shock
XJ27_RS23070	COG3038	cytochrome b561
XJ27_RS23075	COG2353	YceI-like domain
XJ27_RS23080	COG2198	Histidine kinase
XJ27_RS23080	COG2205	protein histidine kinase activity
XJ27_RS23080	COG0784	Response regulator, receiver
XJ27_RS23140	COG0653	protein targeting
XJ27_RS23165	COG2826	transposase and inactivated derivatives, IS30 family
XJ27_RS23185	COG0659	secondary active sulfate transmembrane transporter activity
XJ27_RS23230	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XJ27_RS23240	COG5599	Phosphatase
XJ27_RS23315	COG3328	transposase activity
XJ27_RS23420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XJ27_RS23430	COG2948	multi-organism process
XJ27_RS23460	COG3039	Transposase
XJ27_RS23555	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XJ27_RS23575	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs