locus-tag	class	description
DYQ48_RS00015	COG0187	DNA topoisomerase II activity
DYQ48_RS00025	COG0501	Belongs to the peptidase M48B family
DYQ48_RS00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DYQ48_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DYQ48_RS00100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DYQ48_RS00105	COG0793	Belongs to the peptidase S41A family
DYQ48_RS00110	COG4942	peptidase
DYQ48_RS00120	COG2234	aminopeptidase activity
DYQ48_RS00130	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DYQ48_RS00135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DYQ48_RS00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DYQ48_RS00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DYQ48_RS00150	COG1064	alcohol dehydrogenase
DYQ48_RS00160	COG0493	'glutamate synthase
DYQ48_RS00165	COG0070	glutamate synthase
DYQ48_RS00165	COG0067	glutamate synthase
DYQ48_RS00165	COG0069	glutamate synthase activity
DYQ48_RS00205	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DYQ48_RS00220	COG3459	Glycosyltransferase 36 associated
DYQ48_RS00250	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS00330	COG1111	helicase
DYQ48_RS00330	COG1205	dead DEAH box helicase
DYQ48_RS00340	COG1272	protein, Hemolysin III
DYQ48_RS00365	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS00385	COG0583	DNA-binding transcription factor activity
DYQ48_RS00390	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS00405	COG2249	NAD(P)H dehydrogenase (quinone) activity
DYQ48_RS00420	COG1733	regulation of RNA biosynthetic process
DYQ48_RS00455	COG3237	CsbD-like
DYQ48_RS00495	COG2816	NAD+ diphosphatase activity
DYQ48_RS00500	COG0657	acetylesterase activity
DYQ48_RS00510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DYQ48_RS00555	COG0714	Associated with various cellular activities
DYQ48_RS00610	COG4772	TonB-dependent receptor
DYQ48_RS00620	COG0662	Cupin 2, conserved barrel domain protein
DYQ48_RS00630	COG1012	belongs to the aldehyde dehydrogenase family
DYQ48_RS00685	COG1755	Isoprenylcysteine carboxyl methyltransferase
DYQ48_RS00690	COG4585	Histidine kinase
DYQ48_RS00695	COG2197	response regulator
DYQ48_RS00710	COG3710	Transcriptional regulator
DYQ48_RS00715	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DYQ48_RS00725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYQ48_RS00730	COG4771	TonB-dependent receptor
DYQ48_RS00840	COG3039	Transposase
DYQ48_RS00880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DYQ48_RS00905	COG0366	Alpha amylase catalytic
DYQ48_RS00910	COG0366	Alpha amylase catalytic
DYQ48_RS00915	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DYQ48_RS00945	COG2755	lipolytic protein G-D-S-L family
DYQ48_RS00955	COG0657	acetylesterase activity
DYQ48_RS00955	COG2755	lipolytic protein G-D-S-L family
DYQ48_RS00965	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DYQ48_RS00980	COG3507	Belongs to the glycosyl hydrolase 43 family
DYQ48_RS00985	COG1609	Transcriptional regulator
DYQ48_RS00995	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DYQ48_RS01000	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS01010	COG2755	lipolytic protein G-D-S-L family
DYQ48_RS01030	COG3186	Phenylalanine-4-hydroxylase
DYQ48_RS01035	COG1522	sequence-specific DNA binding
DYQ48_RS01045	COG1752	Esterase of the alpha-beta hydrolase superfamily
DYQ48_RS01050	COG1119	ATPase activity
DYQ48_RS01065	COG1125	glycine betaine transport
DYQ48_RS01065	COG0517	IMP dehydrogenase activity
DYQ48_RS01080	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DYQ48_RS01090	COG3550	peptidyl-serine autophosphorylation
DYQ48_RS01095	COG1396	sequence-specific DNA binding
DYQ48_RS01125	COG0489	protein tyrosine kinase activity
DYQ48_RS01130	COG2062	phosphohistidine phosphatase, SixA
DYQ48_RS01140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DYQ48_RS01175	COG1881	PFAM PEBP family protein
DYQ48_RS01190	COG0174	glutamine synthetase
DYQ48_RS01195	COG0347	Belongs to the P(II) protein family
DYQ48_RS01200	COG0004	ammonium transporteR
DYQ48_RS01205	COG3852	Histidine kinase
DYQ48_RS01210	COG2204	response regulator
DYQ48_RS01215	COG2032	superoxide dismutase activity
DYQ48_RS01220	COG2032	superoxide dismutase activity
DYQ48_RS01230	COG0183	Belongs to the thiolase family
DYQ48_RS01275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DYQ48_RS01285	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DYQ48_RS01295	COG0028	Belongs to the TPP enzyme family
DYQ48_RS01330	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DYQ48_RS01345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DYQ48_RS01350	COG3177	Filamentation induced by cAMP protein fic
DYQ48_RS01355	COG0596	Alpha beta hydrolase
DYQ48_RS01360	COG0727	PFAM Uncharacterised protein family (UPF0153)
DYQ48_RS01365	COG0318	PFAM AMP-dependent synthetase and ligase
DYQ48_RS01380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DYQ48_RS01395	COG1181	Belongs to the D-alanine--D-alanine ligase family
DYQ48_RS01410	COG0564	pseudouridine synthase activity
DYQ48_RS01430	COG1446	asparaginase
DYQ48_RS01435	COG0339	signal peptide processing
DYQ48_RS01455	COG0583	DNA-binding transcription factor activity
DYQ48_RS01460	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DYQ48_RS01465	COG2224	Isocitrate lyase
DYQ48_RS01500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DYQ48_RS01505	COG1960	acyl-CoA dehydrogenase activity
DYQ48_RS01560	COG0523	cobalamin synthesis protein
DYQ48_RS01575	COG0697	spore germination
DYQ48_RS01585	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DYQ48_RS01600	COG1846	Transcriptional regulator
DYQ48_RS01605	COG1764	response to oxidative stress
DYQ48_RS01630	COG0656	L-ascorbic acid biosynthetic process
DYQ48_RS01635	COG2130	NADP-dependent
DYQ48_RS01650	COG1187	pseudouridine synthase activity
DYQ48_RS01665	COG1643	Atp-dependent helicase
DYQ48_RS01670	COG0840	transmembrane signaling receptor activity
DYQ48_RS01680	COG4807	Protein conserved in bacteria
DYQ48_RS01685	COG2351	hydroxyisourate hydrolase activity
DYQ48_RS01690	COG2072	flavoprotein involved in K transport
DYQ48_RS01710	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DYQ48_RS01735	COG0596	Alpha beta hydrolase
DYQ48_RS01810	COG2252	PERMEase
DYQ48_RS01830	COG0084	hydrolase, TatD family'
DYQ48_RS01845	COG0583	DNA-binding transcription factor activity
DYQ48_RS01850	COG2814	Major facilitator Superfamily
DYQ48_RS01875	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DYQ48_RS01880	COG1902	pentaerythritol trinitrate reductase activity
DYQ48_RS01915	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DYQ48_RS01920	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DYQ48_RS01925	COG0583	DNA-binding transcription factor activity
DYQ48_RS01955	COG0702	epimerase
DYQ48_RS01960	COG1733	regulation of RNA biosynthetic process
DYQ48_RS02065	COG0129	dihydroxy-acid dehydratase activity
DYQ48_RS02075	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DYQ48_RS02135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DYQ48_RS02165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DYQ48_RS02170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DYQ48_RS02180	COG3485	protocatechuate 3,4-dioxygenase
DYQ48_RS02195	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DYQ48_RS02200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DYQ48_RS02215	COG1414	Transcriptional regulator
DYQ48_RS02225	COG0657	acetylesterase activity
DYQ48_RS02235	COG0445	tRNA wobble uridine modification
DYQ48_RS02245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DYQ48_RS02285	COG0156	8-amino-7-oxononanoate synthase activity
DYQ48_RS02290	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DYQ48_RS02295	COG1040	competence protein
DYQ48_RS02335	COG3590	peptidase
DYQ48_RS02355	COG1511	domain protein
DYQ48_RS02355	COG3264	Mechanosensitive ion channel
DYQ48_RS02365	COG1368	sulfuric ester hydrolase activity
DYQ48_RS02375	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DYQ48_RS02380	COG2354	Protein conserved in bacteria
DYQ48_RS02385	COG1649	PFAM Uncharacterised BCR, COG1649
DYQ48_RS02395	COG0297	glycogen (starch) synthase activity
DYQ48_RS02400	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DYQ48_RS02405	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DYQ48_RS02430	COG0702	epimerase
DYQ48_RS02435	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS02475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYQ48_RS02485	COG0513	Belongs to the DEAD box helicase family
DYQ48_RS02495	COG0508	dehydrogenase complex catalyzes the overall conversion of
DYQ48_RS02510	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DYQ48_RS02525	COG3104	oligopeptide transport
DYQ48_RS02545	COG2852	Protein conserved in bacteria
DYQ48_RS02565	COG1320	monovalent cation:proton antiporter activity
DYQ48_RS02570	COG2212	antiporter activity
DYQ48_RS02580	COG0651	ATP synthesis coupled electron transport
DYQ48_RS02585	COG1006	Multisubunit Na H antiporter MnhC subunit
DYQ48_RS02590	COG2111	Na H antiporter
DYQ48_RS02590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DYQ48_RS02655	COG1597	lipid kinase activity
DYQ48_RS02675	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DYQ48_RS02705	COG2267	carboxylic ester hydrolase activity
DYQ48_RS02785	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DYQ48_RS02855	COG0840	transmembrane signaling receptor activity
DYQ48_RS02870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DYQ48_RS02875	COG0134	indole-3-glycerol-phosphate synthase activity
DYQ48_RS02885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DYQ48_RS02900	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DYQ48_RS02965	COG0316	Belongs to the HesB IscA family
DYQ48_RS02975	COG2816	NAD+ diphosphatase activity
DYQ48_RS02980	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DYQ48_RS03000	COG2814	Major facilitator Superfamily
DYQ48_RS03005	COG1289	transmembrane transporter activity
DYQ48_RS03010	COG0151	Belongs to the GarS family
DYQ48_RS03025	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DYQ48_RS03050	COG2264	protein methyltransferase activity
DYQ48_RS03065	COG0439	Biotin carboxylase
DYQ48_RS03075	COG0511	ligase activity, forming carbon-carbon bonds
DYQ48_RS03080	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DYQ48_RS03095	COG1324	tolerance protein
DYQ48_RS03100	COG2356	endonuclease I
DYQ48_RS03140	COG3550	peptidyl-serine autophosphorylation
DYQ48_RS03145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DYQ48_RS03170	COG3712	iron ion homeostasis
DYQ48_RS03195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DYQ48_RS03200	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DYQ48_RS03225	COG2353	YceI-like domain
DYQ48_RS03245	COG3052	prosthetic group binding
DYQ48_RS03280	COG1802	Transcriptional regulator
DYQ48_RS03380	COG0210	DNA helicase
DYQ48_RS03485	COG4206	TonB-dependent receptor
DYQ48_RS03490	COG0823	Involved in the tonB-independent uptake of proteins
DYQ48_RS03490	COG1506	peptidase
DYQ48_RS03530	COG0435	Glutathione S-transferase
DYQ48_RS03565	COG1506	peptidase
DYQ48_RS03565	COG0823	Involved in the tonB-independent uptake of proteins
DYQ48_RS03600	COG0697	spore germination
DYQ48_RS03620	COG1113	amino acid transport
DYQ48_RS03640	COG3507	Belongs to the glycosyl hydrolase 43 family
DYQ48_RS03705	COG0840	transmembrane signaling receptor activity
DYQ48_RS03710	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DYQ48_RS03710	COG5297	Belongs to the glycosyl hydrolase family 6
DYQ48_RS03715	COG0659	secondary active sulfate transmembrane transporter activity
DYQ48_RS03745	COG3275	phosphorelay sensor kinase activity
DYQ48_RS03755	COG0181	hydroxymethylbilane synthase activity
DYQ48_RS03780	COG1505	serine-type exopeptidase activity
DYQ48_RS03800	COG0436	Aminotransferase
DYQ48_RS03815	COG2832	Protein of unknown function (DUF454)
DYQ48_RS03825	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DYQ48_RS03835	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DYQ48_RS03840	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DYQ48_RS03845	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DYQ48_RS03850	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DYQ48_RS03880	COG2226	methyltransferase
DYQ48_RS03885	COG5001	Diguanylate cyclase
DYQ48_RS03885	COG3300	MHYT domain
DYQ48_RS03890	COG0308	aminopeptidase N
DYQ48_RS03930	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DYQ48_RS03945	COG3284	Transcriptional regulator
DYQ48_RS03950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYQ48_RS03955	COG1077	Cell shape determining protein MreB Mrl
DYQ48_RS03960	COG1792	Involved in formation and maintenance of cell shape
DYQ48_RS03965	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DYQ48_RS03975	COG0772	Belongs to the SEDS family
DYQ48_RS03990	COG2951	lytic endotransglycosylase activity
DYQ48_RS03995	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DYQ48_RS04000	COG1686	Belongs to the peptidase S11 family
DYQ48_RS04015	COG0321	lipoyl(octanoyl) transferase activity
DYQ48_RS04020	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DYQ48_RS04035	COG1051	belongs to the nudix hydrolase family
DYQ48_RS04035	COG1056	cytidyltransferase-related domain
DYQ48_RS04070	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DYQ48_RS04075	COG0673	inositol 2-dehydrogenase activity
DYQ48_RS04080	COG2823	Periplasmic or secreted lipoprotein
DYQ48_RS04085	COG4251	negative regulation of phosphorylation
DYQ48_RS04090	COG0784	Response regulator, receiver
DYQ48_RS04095	COG4191	Histidine kinase
DYQ48_RS04100	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DYQ48_RS04105	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS04155	COG1459	type II secretion system
DYQ48_RS04180	COG3156	type II secretion system protein K
DYQ48_RS04205	COG3250	beta-galactosidase activity
DYQ48_RS04220	COG2188	Transcriptional regulator
DYQ48_RS04230	COG1609	Transcriptional regulator
DYQ48_RS04235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DYQ48_RS04240	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DYQ48_RS04270	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DYQ48_RS04280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DYQ48_RS04290	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DYQ48_RS04305	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DYQ48_RS04315	COG2205	protein histidine kinase activity
DYQ48_RS04335	COG3920	Histidine kinase
DYQ48_RS04350	COG3791	Glutathione-dependent formaldehyde-activating
DYQ48_RS04360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DYQ48_RS04410	COG0402	S-adenosylhomocysteine deaminase activity
DYQ48_RS04430	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DYQ48_RS04435	COG0726	polysaccharide deacetylase
DYQ48_RS04440	COG4773	Receptor
DYQ48_RS04500	COG3039	Transposase
DYQ48_RS04545	COG2211	Major facilitator Superfamily
DYQ48_RS04550	COG1609	Transcriptional regulator
DYQ48_RS04555	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS04560	COG2851	Citrate transporter
DYQ48_RS04575	COG0642	Histidine kinase
DYQ48_RS04585	COG2197	response regulator
DYQ48_RS04600	COG4191	Histidine kinase
DYQ48_RS04615	COG0281	malic enzyme
DYQ48_RS04615	COG0280	phosphate acetyltransferase
DYQ48_RS04640	COG1560	Kdo2-lipid A biosynthetic process
DYQ48_RS04645	COG1519	Transferase
DYQ48_RS04655	COG1538	Outer membrane efflux protein
DYQ48_RS04660	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DYQ48_RS04680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DYQ48_RS04685	COG0066	3-isopropylmalate dehydratase activity
DYQ48_RS04690	COG2226	methyltransferase
DYQ48_RS04695	COG0473	3-isopropylmalate dehydrogenase activity
DYQ48_RS04705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DYQ48_RS04725	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DYQ48_RS04730	COG0405	Gamma-glutamyltransferase
DYQ48_RS04740	COG1506	peptidase
DYQ48_RS04740	COG0823	Involved in the tonB-independent uptake of proteins
DYQ48_RS04740	COG4946	Tricorn protease homolog
DYQ48_RS04750	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DYQ48_RS04755	COG3710	Transcriptional regulator
DYQ48_RS04775	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DYQ48_RS04785	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DYQ48_RS04805	COG0563	adenylate kinase activity
DYQ48_RS04810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DYQ48_RS04820	COG3781	membrane
DYQ48_RS04830	COG0671	phosphoesterase, PA-phosphatase related
DYQ48_RS04840	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS04855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DYQ48_RS04860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DYQ48_RS04890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DYQ48_RS04895	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
DYQ48_RS04905	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DYQ48_RS04920	COG0352	thiamine-phosphate diphosphorylase activity
DYQ48_RS04925	COG1773	rubredoxin
DYQ48_RS04930	COG2912	Transglutaminase-like superfamily
DYQ48_RS04950	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DYQ48_RS04975	COG0006	proline dipeptidase activity
DYQ48_RS04980	COG0006	proline dipeptidase activity
DYQ48_RS04995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DYQ48_RS05000	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DYQ48_RS05005	COG0346	lactoylglutathione lyase activity
DYQ48_RS05010	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DYQ48_RS05015	COG1561	YicC-like family, N-terminal region
DYQ48_RS05030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DYQ48_RS05040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DYQ48_RS05065	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DYQ48_RS05095	COG0714	Associated with various cellular activities
DYQ48_RS05130	COG1301	dicarboxylic acid transport
DYQ48_RS05145	COG4773	Receptor
DYQ48_RS05150	COG0583	DNA-binding transcription factor activity
DYQ48_RS05155	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS05170	COG1376	ErfK ybiS ycfS ynhG family protein
DYQ48_RS05190	COG3682	Transcriptional regulator
DYQ48_RS05205	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DYQ48_RS05210	COG4149	molybdate abc transporter
DYQ48_RS05215	COG0725	ABC transporter, periplasmic molybdate-binding protein
DYQ48_RS05220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYQ48_RS05220	COG3453	Protein conserved in bacteria
DYQ48_RS05230	COG3047	cAMP biosynthetic process
DYQ48_RS05245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DYQ48_RS05280	COG0469	pyruvate kinase activity
DYQ48_RS05290	COG3588	fructose-bisphosphate aldolase
DYQ48_RS05295	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DYQ48_RS05335	COG0784	Response regulator, receiver
DYQ48_RS05335	COG2198	Histidine kinase
DYQ48_RS05335	COG2205	protein histidine kinase activity
DYQ48_RS05355	COG0175	sulfate reduction
DYQ48_RS05360	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DYQ48_RS05375	COG0529	Catalyzes the synthesis of activated sulfate
DYQ48_RS05375	COG2895	sulfate adenylyltransferase (ATP) activity
DYQ48_RS05380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYQ48_RS05385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYQ48_RS05405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DYQ48_RS05410	COG2272	Belongs to the type-B carboxylesterase lipase family
DYQ48_RS05420	COG4948	Mandelate Racemase Muconate Lactonizing
DYQ48_RS05425	COG3250	beta-galactosidase activity
DYQ48_RS05435	COG1609	Transcriptional regulator
DYQ48_RS05465	COG3273	potassium ion transport
DYQ48_RS05465	COG0471	metal ion transport
DYQ48_RS05470	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DYQ48_RS05540	COG2003	Belongs to the UPF0758 family
DYQ48_RS05720	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DYQ48_RS05765	COG1238	metal cluster binding
DYQ48_RS05770	COG0840	transmembrane signaling receptor activity
DYQ48_RS05805	COG0189	ligase activity
DYQ48_RS05810	COG0745	RESPONSE REGULATOR receiver
DYQ48_RS05845	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DYQ48_RS05850	COG1459	type II secretion system
DYQ48_RS05860	COG4969	Belongs to the N-Me-Phe pilin family
DYQ48_RS05880	COG0045	succinate-CoA ligase (ADP-forming) activity
DYQ48_RS05885	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DYQ48_RS05915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DYQ48_RS05915	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DYQ48_RS05925	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DYQ48_RS05930	COG0564	pseudouridine synthase activity
DYQ48_RS05945	COG3011	Protein conserved in bacteria
DYQ48_RS05950	COG0840	transmembrane signaling receptor activity
DYQ48_RS05965	COG3387	PFAM Glycoside hydrolase 15-related
DYQ48_RS05970	COG1877	trehalose-phosphatase activity
DYQ48_RS06030	COG4771	TonB-dependent receptor
DYQ48_RS06040	COG0667	Aldo Keto reductase
DYQ48_RS06045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DYQ48_RS06050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DYQ48_RS06055	COG1116	anion transmembrane transporter activity
DYQ48_RS06060	COG0542	response to heat
DYQ48_RS06070	COG4206	TonB-dependent receptor
DYQ48_RS06085	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DYQ48_RS06100	COG0019	diaminopimelate decarboxylase activity
DYQ48_RS06105	COG4264	IucA IucC family
DYQ48_RS06115	COG4264	IucA IucC family
DYQ48_RS06125	COG4772	TonB-dependent receptor
DYQ48_RS06135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DYQ48_RS06135	COG4651	solute:proton antiporter activity
DYQ48_RS06160	COG0488	(ABC) transporter
DYQ48_RS06205	COG0477	Major facilitator Superfamily
DYQ48_RS06225	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DYQ48_RS06270	COG2255	four-way junction helicase activity
DYQ48_RS06275	COG0824	Thioesterase
DYQ48_RS06285	COG0848	biopolymer transport protein
DYQ48_RS06300	COG2885	chlorophyll binding
DYQ48_RS06310	COG0602	queuosine metabolic process
DYQ48_RS06315	COG0667	Aldo Keto reductase
DYQ48_RS06370	COG4983	Phage plasmid primase, P4 family domain protein
DYQ48_RS06390	COG0582	viral genome integration into host DNA
DYQ48_RS06400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DYQ48_RS06405	COG3920	Histidine kinase
DYQ48_RS06440	COG1187	pseudouridine synthase activity
DYQ48_RS06460	COG0514	ATP-dependent DNA helicase (RecQ)
DYQ48_RS06465	COG0783	Belongs to the Dps family
DYQ48_RS06470	COG1643	Atp-dependent helicase
DYQ48_RS06480	COG0837	glucose binding
DYQ48_RS06500	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
DYQ48_RS06505	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DYQ48_RS06515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DYQ48_RS06530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DYQ48_RS06540	COG1199	ATP-dependent helicase activity
DYQ48_RS06555	COG0189	ligase activity
DYQ48_RS06570	COG0835	chemotaxis
DYQ48_RS06575	COG0840	transmembrane signaling receptor activity
DYQ48_RS06580	COG2198	Histidine kinase
DYQ48_RS06580	COG0643	Histidine kinase
DYQ48_RS06580	COG0784	Response regulator, receiver
DYQ48_RS06585	COG2201	protein-glutamate methylesterase activity
DYQ48_RS06615	COG1595	DNA-templated transcription, initiation
DYQ48_RS06620	COG2304	oxidoreductase activity
DYQ48_RS06630	COG1446	asparaginase
DYQ48_RS06635	COG3142	Participates in the control of copper homeostasis
DYQ48_RS06685	COG3537	Alpha-1,2-mannosidase
DYQ48_RS06695	COG1486	melibiose metabolic process
DYQ48_RS06705	COG0531	amino acid
DYQ48_RS06720	COG1472	Belongs to the glycosyl hydrolase 3 family
DYQ48_RS06745	COG3858	chitin binding
DYQ48_RS06745	COG1388	LysM domain
DYQ48_RS06760	COG0837	glucose binding
DYQ48_RS06765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DYQ48_RS06775	COG0494	nUDIX hydrolase
DYQ48_RS06780	COG1218	3'(2'),5'-bisphosphate nucleotidase
DYQ48_RS06785	COG3956	TIGRFAM MazG family protein
DYQ48_RS06790	COG1742	UPF0060 membrane protein
DYQ48_RS06795	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DYQ48_RS06800	COG0509	glycine decarboxylation via glycine cleavage system
DYQ48_RS06825	COG3039	Transposase
DYQ48_RS06835	COG1960	acyl-CoA dehydrogenase activity
DYQ48_RS06845	COG1309	transcriptional regulator
DYQ48_RS06860	COG2205	protein histidine kinase activity
DYQ48_RS06865	COG1104	cysteine desulfurase activity
DYQ48_RS06895	COG3039	Transposase
DYQ48_RS06920	COG4206	TonB-dependent receptor
DYQ48_RS06930	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DYQ48_RS06935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DYQ48_RS06940	COG0463	Glycosyl transferase, family 2
DYQ48_RS06945	COG0517	IMP dehydrogenase activity
DYQ48_RS06945	COG0516	GMP reductase activity
DYQ48_RS06950	COG2982	Protein involved in outer membrane biogenesis
DYQ48_RS06955	COG1272	protein, Hemolysin III
DYQ48_RS06960	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DYQ48_RS06970	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DYQ48_RS06975	COG0626	cystathionine gamma-synthase activity
DYQ48_RS06980	COG0460	homoserine dehydrogenase
DYQ48_RS06980	COG0527	aspartate kinase activity
DYQ48_RS06990	COG1760	l-serine dehydratase
DYQ48_RS07005	COG1278	Cold shock
DYQ48_RS07015	COG3038	cytochrome b561
DYQ48_RS07020	COG2353	YceI-like domain
DYQ48_RS07025	COG2205	protein histidine kinase activity
DYQ48_RS07025	COG0784	Response regulator, receiver
DYQ48_RS07025	COG2198	Histidine kinase
DYQ48_RS07030	COG2205	protein histidine kinase activity
DYQ48_RS07030	COG2198	Histidine kinase
DYQ48_RS07030	COG0784	Response regulator, receiver
DYQ48_RS07045	COG0477	Major facilitator Superfamily
DYQ48_RS07055	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DYQ48_RS07065	COG2986	histidine ammonia-lyase
DYQ48_RS07070	COG1228	amidohydrolase
DYQ48_RS07105	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DYQ48_RS07110	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DYQ48_RS07115	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DYQ48_RS07120	COG0077	Prephenate dehydratase
DYQ48_RS07120	COG1605	Chorismate mutase
DYQ48_RS07125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DYQ48_RS07140	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DYQ48_RS07145	COG0583	DNA-binding transcription factor activity
DYQ48_RS07200	COG0840	transmembrane signaling receptor activity
DYQ48_RS07220	COG0784	Response regulator, receiver
DYQ48_RS07220	COG2205	protein histidine kinase activity
DYQ48_RS07220	COG5002	protein histidine kinase activity
DYQ48_RS07225	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
DYQ48_RS07230	COG4191	Histidine kinase
DYQ48_RS07230	COG0784	Response regulator, receiver
DYQ48_RS07245	COG3039	Transposase
DYQ48_RS07250	COG2879	small protein
DYQ48_RS07255	COG1966	Carbon starvation protein
DYQ48_RS07260	COG1741	Belongs to the pirin family
DYQ48_RS07275	COG1741	Belongs to the pirin family
DYQ48_RS07280	COG1515	deoxyribonuclease V activity
DYQ48_RS07295	COG3590	peptidase
DYQ48_RS07300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DYQ48_RS07310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DYQ48_RS07320	COG0835	chemotaxis
DYQ48_RS07325	COG0840	transmembrane signaling receptor activity
DYQ48_RS07330	COG0643	Histidine kinase
DYQ48_RS07330	COG2198	Histidine kinase
DYQ48_RS07340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DYQ48_RS07355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DYQ48_RS07360	COG0745	RESPONSE REGULATOR receiver
DYQ48_RS07365	COG2205	protein histidine kinase activity
DYQ48_RS07375	COG4452	Inner membrane protein CreD
DYQ48_RS07400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DYQ48_RS07405	COG0735	belongs to the Fur family
DYQ48_RS07420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYQ48_RS07430	COG1309	transcriptional regulator
DYQ48_RS07435	COG0667	Aldo Keto reductase
DYQ48_RS07460	COG0583	DNA-binding transcription factor activity
DYQ48_RS07465	COG2814	Major facilitator Superfamily
DYQ48_RS07470	COG0667	Aldo Keto reductase
DYQ48_RS07475	COG1404	Belongs to the peptidase S8 family
DYQ48_RS07485	COG1404	Belongs to the peptidase S8 family
DYQ48_RS07580	COG1595	DNA-templated transcription, initiation
DYQ48_RS07590	COG5002	protein histidine kinase activity
DYQ48_RS07590	COG5001	Diguanylate cyclase
DYQ48_RS07595	COG1187	pseudouridine synthase activity
DYQ48_RS07615	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DYQ48_RS07625	COG0475	glutathione-regulated potassium exporter activity
DYQ48_RS07635	COG1132	(ABC) transporter
DYQ48_RS07680	COG2155	Conserved Protein
DYQ48_RS07690	COG0583	DNA-binding transcription factor activity
DYQ48_RS07705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYQ48_RS07735	COG3706	GGDEF domain
DYQ48_RS07790	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DYQ48_RS07805	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DYQ48_RS07815	COG0497	DNA recombination
DYQ48_RS07820	COG1420	regulation of RNA biosynthetic process
DYQ48_RS07825	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DYQ48_RS07840	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DYQ48_RS07865	COG2274	protein secretion by the type I secretion system
DYQ48_RS07870	COG0583	DNA-binding transcription factor activity
DYQ48_RS07875	COG1132	(ABC) transporter
DYQ48_RS07910	COG2850	peptidyl-arginine hydroxylation
DYQ48_RS07930	COG1253	flavin adenine dinucleotide binding
DYQ48_RS07960	COG1131	(ABC) transporter
DYQ48_RS07965	COG1725	Transcriptional regulator
DYQ48_RS07975	COG0386	Belongs to the glutathione peroxidase family
DYQ48_RS07990	COG2900	Belongs to the SlyX family
DYQ48_RS08015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYQ48_RS08030	COG0646	methionine synthase
DYQ48_RS08030	COG1410	methionine synthase
DYQ48_RS08040	COG2226	methyltransferase
DYQ48_RS08045	COG1960	acyl-CoA dehydrogenase activity
DYQ48_RS08060	COG0557	exoribonuclease II activity
DYQ48_RS08070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DYQ48_RS08090	COG0704	Plays a role in the regulation of phosphate uptake
DYQ48_RS08100	COG0581	inorganic phosphate transmembrane transporter activity
DYQ48_RS08105	COG0573	inorganic phosphate transmembrane transporter activity
DYQ48_RS08110	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DYQ48_RS08135	COG0659	secondary active sulfate transmembrane transporter activity
DYQ48_RS08145	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DYQ48_RS08155	COG1024	Enoyl-CoA hydratase
DYQ48_RS08200	COG0488	(ABC) transporter
DYQ48_RS08215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DYQ48_RS08225	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DYQ48_RS08240	COG2925	Exonuclease
DYQ48_RS08245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DYQ48_RS08265	COG0288	reversible hydration of carbon dioxide
DYQ48_RS08270	COG2808	Putative FMN-binding domain
DYQ48_RS08285	COG0017	Asparaginyl-tRNA synthetase
DYQ48_RS08290	COG0316	Belongs to the HesB IscA family
DYQ48_RS08315	COG3115	cell septum assembly
DYQ48_RS08320	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DYQ48_RS08325	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DYQ48_RS08330	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DYQ48_RS08340	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DYQ48_RS08370	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DYQ48_RS08375	COG3178	'Phosphotransferase
DYQ48_RS08385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DYQ48_RS08390	COG1555	photosystem II stabilization
DYQ48_RS08400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DYQ48_RS08405	COG1477	protein flavinylation
DYQ48_RS08430	COG3128	pkhd-type hydroxylase
DYQ48_RS08435	COG4774	siderophore transport
DYQ48_RS08450	COG0456	acetyltransferase
DYQ48_RS08455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DYQ48_RS08460	COG0719	Fe-S assembly protein
DYQ48_RS08465	COG0396	ATPase activity
DYQ48_RS08470	COG0719	Fe-S assembly protein
DYQ48_RS08475	COG1959	2 iron, 2 sulfur cluster binding
DYQ48_RS08500	COG4942	peptidase
DYQ48_RS08515	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DYQ48_RS08535	COG0519	Catalyzes the synthesis of GMP from XMP
DYQ48_RS08545	COG1678	Uncharacterized ACR, COG1678
DYQ48_RS08550	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DYQ48_RS08560	COG1764	response to oxidative stress
DYQ48_RS08570	COG0384	phenazine biosynthesis protein PhzF
DYQ48_RS08575	COG0384	phenazine biosynthesis protein PhzF
DYQ48_RS08580	COG0527	aspartate kinase activity
DYQ48_RS08600	COG0142	geranyltranstransferase activity
DYQ48_RS08605	COG0629	single-stranded DNA binding
DYQ48_RS08620	COG2203	Gaf domain
DYQ48_RS08620	COG3706	GGDEF domain
DYQ48_RS08620	COG4251	negative regulation of phosphorylation
DYQ48_RS08620	COG5001	Diguanylate cyclase
DYQ48_RS08625	COG2080	2 iron, 2 sulfur cluster binding
DYQ48_RS08630	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DYQ48_RS08635	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DYQ48_RS08640	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DYQ48_RS08670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DYQ48_RS08705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DYQ48_RS08715	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DYQ48_RS08725	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DYQ48_RS08775	COG2244	polysaccharide biosynthetic process
DYQ48_RS08805	COG2264	protein methyltransferase activity
DYQ48_RS08810	COG0297	glycogen (starch) synthase activity
DYQ48_RS08815	COG0438	transferase activity, transferring glycosyl groups
DYQ48_RS08830	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
DYQ48_RS08835	COG1132	(ABC) transporter
DYQ48_RS08840	COG0477	Major facilitator Superfamily
DYQ48_RS08845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DYQ48_RS08860	COG1253	flavin adenine dinucleotide binding
DYQ48_RS08900	COG0504	CTP synthase activity
DYQ48_RS08915	COG0148	phosphopyruvate hydratase activity
DYQ48_RS08925	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DYQ48_RS08930	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DYQ48_RS08940	COG2840	Smr protein MutS2
DYQ48_RS08945	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DYQ48_RS08950	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DYQ48_RS08955	COG1238	metal cluster binding
DYQ48_RS08970	COG1534	Rna-binding protein
DYQ48_RS08975	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DYQ48_RS08985	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DYQ48_RS08990	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DYQ48_RS09000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DYQ48_RS09005	COG1546	Belongs to the CinA family
DYQ48_RS09010	COG4771	TonB-dependent receptor
DYQ48_RS09015	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DYQ48_RS09025	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DYQ48_RS09030	COG2137	regulation of response to DNA damage stimulus
DYQ48_RS09035	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DYQ48_RS09040	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DYQ48_RS09055	COG1741	Belongs to the pirin family
DYQ48_RS09080	COG0351	phosphomethylpyrimidine kinase
DYQ48_RS09080	COG0352	thiamine-phosphate diphosphorylase activity
DYQ48_RS09095	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DYQ48_RS09100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DYQ48_RS09115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYQ48_RS09125	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DYQ48_RS09140	COG4948	Mandelate Racemase Muconate Lactonizing
DYQ48_RS09145	COG0800	Aldolase
DYQ48_RS09180	COG1501	Belongs to the glycosyl hydrolase 31 family
DYQ48_RS09190	COG1070	Carbohydrate kinase
DYQ48_RS09195	COG2115	Belongs to the xylose isomerase family
DYQ48_RS09200	COG0477	Major facilitator Superfamily
DYQ48_RS09220	COG0860	N-Acetylmuramoyl-L-alanine amidase
DYQ48_RS09240	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DYQ48_RS09245	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DYQ48_RS09250	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DYQ48_RS09255	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DYQ48_RS09290	COG1472	Belongs to the glycosyl hydrolase 3 family
DYQ48_RS09305	COG3706	GGDEF domain
DYQ48_RS09305	COG4251	negative regulation of phosphorylation
DYQ48_RS09305	COG5001	Diguanylate cyclase
DYQ48_RS09305	COG2203	Gaf domain
DYQ48_RS09310	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DYQ48_RS09320	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DYQ48_RS09330	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DYQ48_RS09335	COG0671	phosphoesterase, PA-phosphatase related
DYQ48_RS09350	COG0697	spore germination
DYQ48_RS09355	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DYQ48_RS09360	COG0167	dihydroorotate dehydrogenase activity
DYQ48_RS09375	COG1012	belongs to the aldehyde dehydrogenase family
DYQ48_RS09425	COG1215	transferase activity, transferring glycosyl groups
DYQ48_RS09430	COG0726	polysaccharide deacetylase
DYQ48_RS09430	COG1649	PFAM Uncharacterised BCR, COG1649
DYQ48_RS09460	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DYQ48_RS09465	COG0527	aspartate kinase activity
DYQ48_RS09465	COG0460	homoserine dehydrogenase
DYQ48_RS09490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DYQ48_RS09510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DYQ48_RS09515	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DYQ48_RS09520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DYQ48_RS09525	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DYQ48_RS09525	COG0131	Imidazoleglycerol-phosphate dehydratase
DYQ48_RS09540	COG0107	imidazoleglycerol-phosphate synthase activity
DYQ48_RS09545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DYQ48_RS09545	COG0140	phosphoribosyl-ATP diphosphatase activity
DYQ48_RS09560	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DYQ48_RS09580	COG0531	amino acid
DYQ48_RS09585	COG0531	amino acid
DYQ48_RS09600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DYQ48_RS09605	COG0277	FAD linked oxidase domain protein
DYQ48_RS09625	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DYQ48_RS09640	COG1024	Enoyl-CoA hydratase
DYQ48_RS09660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DYQ48_RS09665	COG2258	MOSC domain
DYQ48_RS09675	COG0505	Belongs to the CarA family
DYQ48_RS09685	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DYQ48_RS09690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DYQ48_RS09700	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DYQ48_RS09725	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DYQ48_RS09735	COG2198	Histidine kinase
DYQ48_RS09735	COG0784	Response regulator, receiver
DYQ48_RS09735	COG2205	protein histidine kinase activity
DYQ48_RS09740	COG2205	protein histidine kinase activity
DYQ48_RS09740	COG2198	Histidine kinase
DYQ48_RS09740	COG0784	Response regulator, receiver
DYQ48_RS09780	COG2267	carboxylic ester hydrolase activity
DYQ48_RS09800	COG2201	protein-glutamate methylesterase activity
DYQ48_RS09815	COG0840	transmembrane signaling receptor activity
DYQ48_RS09825	COG0835	chemotaxis
DYQ48_RS09840	COG0840	transmembrane signaling receptor activity
DYQ48_RS09845	COG0840	transmembrane signaling receptor activity
DYQ48_RS09850	COG0840	transmembrane signaling receptor activity
DYQ48_RS09855	COG0840	transmembrane signaling receptor activity
DYQ48_RS09860	COG0840	transmembrane signaling receptor activity
DYQ48_RS09865	COG0840	transmembrane signaling receptor activity
DYQ48_RS09870	COG0840	transmembrane signaling receptor activity
DYQ48_RS09875	COG0840	transmembrane signaling receptor activity
DYQ48_RS09895	COG0840	transmembrane signaling receptor activity
DYQ48_RS09905	COG0643	Histidine kinase
DYQ48_RS09905	COG2198	Histidine kinase
DYQ48_RS09910	COG0745	RESPONSE REGULATOR receiver
DYQ48_RS09920	COG0835	chemotaxis
DYQ48_RS09925	COG1192	Involved in chromosome partitioning
DYQ48_RS09935	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DYQ48_RS09950	COG0784	Response regulator, receiver
DYQ48_RS09950	COG2198	Histidine kinase
DYQ48_RS09950	COG0643	Histidine kinase
DYQ48_RS10005	COG3300	MHYT domain
DYQ48_RS10005	COG5001	Diguanylate cyclase
DYQ48_RS10025	COG3190	flagellar
DYQ48_RS10075	COG1677	Flagellar hook-basal body complex protein FliE
DYQ48_RS10080	COG3039	Transposase
DYQ48_RS10135	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS10140	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS10145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DYQ48_RS10165	COG2201	protein-glutamate methylesterase activity
DYQ48_RS10195	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DYQ48_RS10200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DYQ48_RS10215	COG1705	Flagellar rod assembly protein muramidase FlgJ
DYQ48_RS10215	COG3951	Flagellar rod assembly protein muramidase FlgJ
DYQ48_RS10235	COG4787	bacterial-type flagellum-dependent cell motility
DYQ48_RS10245	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DYQ48_RS10250	COG1558	bacterial-type flagellum-dependent cell motility
DYQ48_RS10260	COG0835	chemotaxis
DYQ48_RS10260	COG0784	Response regulator, receiver
DYQ48_RS10280	COG4191	Histidine kinase
DYQ48_RS10325	COG0482	sulfurtransferase activity
DYQ48_RS10340	COG0542	response to heat
DYQ48_RS10350	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DYQ48_RS10360	COG0492	ferredoxin-NADP+ reductase activity
DYQ48_RS10365	COG1674	ftsk spoiiie
DYQ48_RS10380	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DYQ48_RS10385	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DYQ48_RS10390	COG0183	Belongs to the thiolase family
DYQ48_RS10395	COG1024	Enoyl-CoA hydratase
DYQ48_RS10395	COG1250	3-hydroxyacyl-CoA dehydrogenase
DYQ48_RS10410	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DYQ48_RS10430	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DYQ48_RS10435	COG1160	GTP binding
DYQ48_RS10440	COG0303	'Molybdopterin
DYQ48_RS10445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DYQ48_RS10455	COG0708	Exodeoxyribonuclease III
DYQ48_RS10465	COG0303	'Molybdopterin
DYQ48_RS10470	COG0746	molybdenum cofactor guanylyltransferase activity
DYQ48_RS10480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DYQ48_RS10480	COG1648	precorrin-2 dehydrogenase activity
DYQ48_RS10490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DYQ48_RS10500	COG2223	nitrite transmembrane transporter activity
DYQ48_RS10505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DYQ48_RS10515	COG0243	molybdopterin cofactor binding
DYQ48_RS10535	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DYQ48_RS10545	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DYQ48_RS10555	COG0579	oxidoreductase
DYQ48_RS10570	COG3685	Protein conserved in bacteria
DYQ48_RS10585	COG5001	Diguanylate cyclase
DYQ48_RS10655	COG4191	Histidine kinase
DYQ48_RS10655	COG0784	Response regulator, receiver
DYQ48_RS10690	COG3781	membrane
DYQ48_RS10695	COG4191	Histidine kinase
DYQ48_RS10700	COG2197	response regulator
DYQ48_RS10730	COG0840	transmembrane signaling receptor activity
DYQ48_RS10755	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS10785	COG1322	Protein conserved in bacteria
DYQ48_RS10820	COG2154	pterin-4-alpha-carbinolamine dehydratase
DYQ48_RS10895	COG1530	ribonuclease E activity
DYQ48_RS10905	COG1054	Belongs to the UPF0176 family
DYQ48_RS10925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DYQ48_RS10950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DYQ48_RS10955	COG0322	excinuclease ABC activity
DYQ48_RS10965	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DYQ48_RS10970	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DYQ48_RS10975	COG1663	tetraacyldisaccharide 4'-kinase activity
DYQ48_RS10980	COG1132	(ABC) transporter
DYQ48_RS10990	COG0811	peptide transport
DYQ48_RS11010	COG4591	ABC-type transport system involved in lipoprotein release permease component
DYQ48_RS11020	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DYQ48_RS11025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DYQ48_RS11040	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DYQ48_RS11045	COG2009	succinate dehydrogenase
DYQ48_RS11055	COG0354	folic acid binding
DYQ48_RS11065	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DYQ48_RS11070	COG0837	glucose binding
DYQ48_RS11075	COG0363	glucosamine-6-phosphate deaminase activity
DYQ48_RS11080	COG0129	dihydroxy-acid dehydratase activity
DYQ48_RS11085	COG0800	Aldolase
DYQ48_RS11160	COG5002	protein histidine kinase activity
DYQ48_RS11160	COG0784	Response regulator, receiver
DYQ48_RS11160	COG2205	protein histidine kinase activity
DYQ48_RS11170	COG2183	response to ionizing radiation
DYQ48_RS11195	COG3243	poly(R)-hydroxyalkanoic acid synthase
DYQ48_RS11205	COG1183	phosphatidylcholine synthase activity
DYQ48_RS11210	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS11235	COG0668	transmembrane transport
DYQ48_RS11240	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DYQ48_RS11255	COG1914	H( )-stimulated, divalent metal cation uptake system
DYQ48_RS11305	COG1396	sequence-specific DNA binding
DYQ48_RS11395	COG1487	ribonuclease activity
DYQ48_RS11400	COG4691	Plasmid stability protein
DYQ48_RS11490	COG0582	viral genome integration into host DNA
DYQ48_RS11510	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DYQ48_RS11520	COG0475	glutathione-regulated potassium exporter activity
DYQ48_RS11520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DYQ48_RS11525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DYQ48_RS11535	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DYQ48_RS11540	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DYQ48_RS11550	COG0776	regulation of translation
DYQ48_RS11575	COG2957	Belongs to the agmatine deiminase family
DYQ48_RS11580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DYQ48_RS11605	COG0395	ABC-type sugar transport system, permease component
DYQ48_RS11610	COG1175	transmembrane transport
DYQ48_RS11615	COG1653	transport
DYQ48_RS11640	COG2350	Protein conserved in bacteria
DYQ48_RS11645	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DYQ48_RS11650	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DYQ48_RS11655	COG1187	pseudouridine synthase activity
DYQ48_RS11675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DYQ48_RS11680	COG0436	Aminotransferase
DYQ48_RS11705	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DYQ48_RS11745	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DYQ48_RS11750	COG4988	ABC transporter
DYQ48_RS11760	COG1294	oxidase, subunit
DYQ48_RS11795	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DYQ48_RS11810	COG0165	Argininosuccinate lyase
DYQ48_RS11825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DYQ48_RS11830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DYQ48_RS11835	COG0137	argininosuccinate synthase activity
DYQ48_RS11840	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DYQ48_RS11855	COG0215	cysteine-tRNA ligase activity
DYQ48_RS11860	COG2166	iron-sulfur cluster assembly
DYQ48_RS11880	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DYQ48_RS11900	COG4302	ethanolamine ammonia-lyase activity
DYQ48_RS11965	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DYQ48_RS11970	COG0402	S-adenosylhomocysteine deaminase activity
DYQ48_RS11985	COG1509	lysine 2,3-aminomutase activity
DYQ48_RS11990	COG5001	Diguanylate cyclase
DYQ48_RS11990	COG3300	MHYT domain
DYQ48_RS12005	COG0483	inositol monophosphate 1-phosphatase activity
DYQ48_RS12010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DYQ48_RS12035	COG0628	permease
DYQ48_RS12050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DYQ48_RS12075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DYQ48_RS12080	COG0271	Belongs to the BolA IbaG family
DYQ48_RS12090	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DYQ48_RS12100	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DYQ48_RS12105	COG1137	ATPase activity
DYQ48_RS12120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DYQ48_RS12140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DYQ48_RS12145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DYQ48_RS12155	COG2239	Acts as a magnesium transporter
DYQ48_RS12165	COG1294	oxidase, subunit
DYQ48_RS12170	COG1271	oxidase subunit
DYQ48_RS12180	COG1113	amino acid transport
DYQ48_RS12195	COG2197	response regulator
DYQ48_RS12200	COG0531	amino acid
DYQ48_RS12255	COG2814	Major facilitator Superfamily
DYQ48_RS12260	COG0754	glutathionylspermidine amidase activity
DYQ48_RS12285	COG1842	Phage shock protein A
DYQ48_RS12300	COG0259	pyridoxamine-phosphate oxidase activity
DYQ48_RS12305	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DYQ48_RS12310	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DYQ48_RS12320	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DYQ48_RS12325	COG0488	(ABC) transporter
DYQ48_RS12330	COG0513	Belongs to the DEAD box helicase family
DYQ48_RS12335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DYQ48_RS12340	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DYQ48_RS12350	COG0625	glutathione transferase activity
DYQ48_RS12360	COG1671	Belongs to the UPF0178 family
DYQ48_RS12365	COG4681	YaeQ
DYQ48_RS12370	COG2081	HI0933 family
DYQ48_RS12375	COG3300	MHYT domain
DYQ48_RS12375	COG5001	Diguanylate cyclase
DYQ48_RS12385	COG0501	Belongs to the peptidase M48B family
DYQ48_RS12390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DYQ48_RS12395	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS12415	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DYQ48_RS12420	COG0860	N-Acetylmuramoyl-L-alanine amidase
DYQ48_RS12430	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DYQ48_RS12430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DYQ48_RS12435	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DYQ48_RS12450	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DYQ48_RS12480	COG0835	chemotaxis
DYQ48_RS12485	COG0840	transmembrane signaling receptor activity
DYQ48_RS12495	COG1201	RNA secondary structure unwinding
DYQ48_RS12505	COG2969	positive regulation of protein catabolic process
DYQ48_RS12510	COG0625	glutathione transferase activity
DYQ48_RS12520	COG2857	Cytochrome c1
DYQ48_RS12525	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DYQ48_RS12530	COG0723	plastoquinol--plastocyanin reductase activity
DYQ48_RS12535	COG0741	lytic transglycosylase activity
DYQ48_RS12550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DYQ48_RS12555	COG1702	phosphate starvation-inducible protein PhoH
DYQ48_RS12575	COG4535	Mg2 and Co2 transporter CorC
DYQ48_RS12595	COG1012	belongs to the aldehyde dehydrogenase family
DYQ48_RS12605	COG1177	transmembrane transport
DYQ48_RS12610	COG1176	ABC-type spermidine putrescine transport system, permease component I
DYQ48_RS12620	COG3842	ATPase activity
DYQ48_RS12655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DYQ48_RS12660	COG0174	glutamine synthetase
DYQ48_RS12665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DYQ48_RS12695	COG0243	molybdopterin cofactor binding
DYQ48_RS12705	COG2223	nitrite transmembrane transporter activity
DYQ48_RS12710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DYQ48_RS12720	COG2733	membrane
DYQ48_RS12725	COG0784	Response regulator, receiver
DYQ48_RS12725	COG5002	protein histidine kinase activity
DYQ48_RS12725	COG2205	protein histidine kinase activity
DYQ48_RS12735	COG0477	Major facilitator Superfamily
DYQ48_RS12745	COG0604	alcohol dehydrogenase
DYQ48_RS12750	COG0300	oxidoreductase activity
DYQ48_RS12760	COG1902	pentaerythritol trinitrate reductase activity
DYQ48_RS12770	COG3321	synthase
DYQ48_RS12770	COG0604	alcohol dehydrogenase
DYQ48_RS12805	COG2902	Dehydrogenase
DYQ48_RS12815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYQ48_RS12820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYQ48_RS12825	COG1609	Transcriptional regulator
DYQ48_RS12830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DYQ48_RS12830	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DYQ48_RS12835	COG1105	Belongs to the carbohydrate kinase PfkB family
DYQ48_RS12840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DYQ48_RS12840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DYQ48_RS12905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DYQ48_RS12915	COG1862	Preprotein translocase
DYQ48_RS12920	COG0343	queuine tRNA-ribosyltransferase activity
DYQ48_RS12925	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DYQ48_RS12970	COG3291	Pkd domain containing protein
DYQ48_RS12980	COG0405	Gamma-glutamyltransferase
DYQ48_RS12985	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DYQ48_RS13005	COG0742	ribosomal rna small subunit methyltransferase
DYQ48_RS13120	COG0531	amino acid
DYQ48_RS13135	COG0006	proline dipeptidase activity
DYQ48_RS13145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYQ48_RS13160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DYQ48_RS13165	COG3938	Belongs to the proline racemase family
DYQ48_RS13175	COG0552	protein localization to endoplasmic reticulum
DYQ48_RS13180	COG1194	a g-specific adenine glycosylase
DYQ48_RS13210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DYQ48_RS13230	COG3040	lipid binding
DYQ48_RS13240	COG1960	acyl-CoA dehydrogenase activity
DYQ48_RS13250	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DYQ48_RS13270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DYQ48_RS13275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYQ48_RS13280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DYQ48_RS13305	COG0438	transferase activity, transferring glycosyl groups
DYQ48_RS13315	COG0438	transferase activity, transferring glycosyl groups
DYQ48_RS13320	COG0438	transferase activity, transferring glycosyl groups
DYQ48_RS13370	COG0072	phenylalanine-tRNA ligase activity
DYQ48_RS13370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYQ48_RS13375	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DYQ48_RS13390	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DYQ48_RS13395	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DYQ48_RS13460	COG3702	type iv secretory pathway
DYQ48_RS13480	COG2948	multi-organism process
DYQ48_RS13500	COG3505	Type IV secretory pathway VirD4
DYQ48_RS13515	COG0556	nucleotide-excision repair
DYQ48_RS13560	COG1611	Belongs to the LOG family
DYQ48_RS13570	COG2095	MarC family integral membrane protein
DYQ48_RS13575	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS13580	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DYQ48_RS13625	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DYQ48_RS13630	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DYQ48_RS13635	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DYQ48_RS13640	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DYQ48_RS13645	COG0195	Participates in both transcription termination and antitermination
DYQ48_RS13650	COG0779	Required for maturation of 30S ribosomal subunits
DYQ48_RS13660	COG1007	ATP synthesis coupled electron transport
DYQ48_RS13680	COG0839	Belongs to the complex I subunit 6 family
DYQ48_RS13690	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DYQ48_RS13700	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DYQ48_RS13705	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DYQ48_RS13710	COG0649	NAD binding
DYQ48_RS13715	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYQ48_RS13725	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYQ48_RS13745	COG4221	oxidoreductase activity
DYQ48_RS13785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DYQ48_RS13795	COG0159	tryptophan synthase activity
DYQ48_RS13805	COG0133	tryptophan synthase activity
DYQ48_RS13815	COG0135	phosphoribosylanthranilate isomerase activity
DYQ48_RS13820	COG0101	tRNA pseudouridine synthase activity
DYQ48_RS13835	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DYQ48_RS13840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DYQ48_RS13855	COG2890	protein-(glutamine-N5) methyltransferase activity
DYQ48_RS13865	COG0688	phosphatidylethanolamine metabolic process
DYQ48_RS13875	COG0433	COG0433 Predicted ATPase
DYQ48_RS13925	COG1472	Belongs to the glycosyl hydrolase 3 family
DYQ48_RS13945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DYQ48_RS13975	COG0717	Belongs to the dCTP deaminase family
DYQ48_RS13985	COG0489	protein tyrosine kinase activity
DYQ48_RS14010	COG3590	peptidase
DYQ48_RS14035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DYQ48_RS14040	COG2311	Membrane
DYQ48_RS14045	COG1047	Peptidyl-prolyl cis-trans
DYQ48_RS14050	COG0791	NLP P60 protein
DYQ48_RS14055	COG0791	NLP P60 protein
DYQ48_RS14070	COG1301	dicarboxylic acid transport
DYQ48_RS14075	COG1785	Belongs to the alkaline phosphatase family
DYQ48_RS14080	COG0037	tRNA processing
DYQ48_RS14085	COG1722	exodeoxyribonuclease VII activity
DYQ48_RS14090	COG0142	geranyltranstransferase activity
DYQ48_RS14095	COG4104	PAAR repeat-containing protein
DYQ48_RS14105	COG0312	modulator of DNA gyrase
DYQ48_RS14115	COG0312	modulator of DNA gyrase
DYQ48_RS14125	COG3164	Protein of unknown function
DYQ48_RS14150	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DYQ48_RS14170	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DYQ48_RS14185	COG0495	leucyl-tRNA aminoacylation
DYQ48_RS14195	COG3118	belongs to the thioredoxin family
DYQ48_RS14210	COG0415	Belongs to the DNA photolyase family
DYQ48_RS14220	COG0305	Participates in initiation and elongation during chromosome replication
DYQ48_RS14230	COG0367	asparagine synthase
DYQ48_RS14245	COG1960	acyl-CoA dehydrogenase activity
DYQ48_RS14260	COG0084	hydrolase, TatD family'
DYQ48_RS14265	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DYQ48_RS14300	COG0288	reversible hydration of carbon dioxide
DYQ48_RS14330	COG0386	Belongs to the glutathione peroxidase family
DYQ48_RS14335	COG0339	signal peptide processing
DYQ48_RS14390	COG2814	Major facilitator Superfamily
DYQ48_RS14395	COG1566	PFAM secretion protein HlyD family protein
DYQ48_RS14445	COG4774	siderophore transport
DYQ48_RS14455	COG0367	asparagine synthase
DYQ48_RS14460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DYQ48_RS14465	COG1393	Belongs to the ArsC family
DYQ48_RS14480	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DYQ48_RS14525	COG0052	Belongs to the universal ribosomal protein uS2 family
DYQ48_RS14530	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DYQ48_RS14540	COG0528	UMP kinase activity
DYQ48_RS14550	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DYQ48_RS14555	COG0575	Belongs to the CDS family
DYQ48_RS14560	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DYQ48_RS14565	COG0750	zinc metalloprotease
DYQ48_RS14580	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DYQ48_RS14585	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DYQ48_RS14590	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DYQ48_RS14595	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DYQ48_RS14610	COG0825	malonyl-CoA metabolic process
DYQ48_RS14620	COG1981	membrane
DYQ48_RS14650	COG1695	Transcriptional regulator
DYQ48_RS14675	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DYQ48_RS14695	COG2040	homocysteine
DYQ48_RS14700	COG0833	amino acid
DYQ48_RS14705	COG0346	lactoylglutathione lyase activity
DYQ48_RS14710	COG1131	(ABC) transporter
DYQ48_RS14725	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYQ48_RS14725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYQ48_RS14735	COG2878	Part of a membrane complex involved in electron transport
DYQ48_RS14750	COG1595	DNA-templated transcription, initiation
DYQ48_RS14795	COG0251	oxidation-reduction process
DYQ48_RS14805	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DYQ48_RS14805	COG0392	lysyltransferase activity
DYQ48_RS14840	COG2814	Major facilitator Superfamily
DYQ48_RS14845	COG1902	pentaerythritol trinitrate reductase activity
DYQ48_RS14860	COG2824	Alkylphosphonate utilization operon protein PhnA
DYQ48_RS14870	COG1047	Peptidyl-prolyl cis-trans
DYQ48_RS14910	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DYQ48_RS14920	COG5487	UPF0391 membrane protein
DYQ48_RS14925	COG1451	nucleotide metabolic process
DYQ48_RS14945	COG0183	Belongs to the thiolase family
DYQ48_RS14975	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DYQ48_RS14975	COG1793	dna ligase
DYQ48_RS14985	COG1793	dna ligase
DYQ48_RS14990	COG1201	RNA secondary structure unwinding
DYQ48_RS15005	COG1278	Cold shock
DYQ48_RS15010	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DYQ48_RS15015	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DYQ48_RS15020	COG1472	Belongs to the glycosyl hydrolase 3 family
DYQ48_RS15025	COG3046	protein related to deoxyribodipyrimidine photolyase
DYQ48_RS15030	COG1233	COG1233 Phytoene dehydrogenase and related
DYQ48_RS15035	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DYQ48_RS15040	COG2954	triphosphatase activity
DYQ48_RS15065	COG1381	Involved in DNA repair and RecF pathway recombination
DYQ48_RS15070	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DYQ48_RS15095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DYQ48_RS15110	COG1024	Enoyl-CoA hydratase
DYQ48_RS15110	COG1250	3-hydroxyacyl-CoA dehydrogenase
DYQ48_RS15120	COG0457	Tetratricopeptide repeat
DYQ48_RS15160	COG1024	Enoyl-CoA hydratase
DYQ48_RS15165	COG1960	acyl-CoA dehydrogenase activity
DYQ48_RS15185	COG3867	Arabinogalactan endo-beta-1,4-galactanase
DYQ48_RS15190	COG3250	beta-galactosidase activity
DYQ48_RS15195	COG4948	Mandelate Racemase Muconate Lactonizing
DYQ48_RS15200	COG1301	dicarboxylic acid transport
DYQ48_RS15205	COG0583	DNA-binding transcription factor activity
DYQ48_RS15225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DYQ48_RS15260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DYQ48_RS15270	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DYQ48_RS15285	COG0534	Mate efflux family protein
DYQ48_RS15295	COG0336	Belongs to the RNA methyltransferase TrmD family
DYQ48_RS15300	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DYQ48_RS15325	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DYQ48_RS15375	COG3534	alpha-L-arabinofuranosidase
DYQ48_RS15400	COG0784	Response regulator, receiver
DYQ48_RS15400	COG4191	Histidine kinase
DYQ48_RS15405	COG4999	Histidine kinase
DYQ48_RS15405	COG2205	protein histidine kinase activity
DYQ48_RS15405	COG3437	response regulator, receiver
DYQ48_RS15405	COG3850	Histidine kinase
DYQ48_RS15410	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DYQ48_RS15415	COG2201	protein-glutamate methylesterase activity
DYQ48_RS15420	COG2205	protein histidine kinase activity
DYQ48_RS15425	COG5507	3-demethylubiquinone-9 3-methyltransferase
DYQ48_RS15435	COG4771	TonB-dependent receptor
DYQ48_RS15460	COG2172	sigma factor antagonist activity
DYQ48_RS15465	COG1366	Belongs to the anti-sigma-factor antagonist family
DYQ48_RS15470	COG1366	Belongs to the anti-sigma-factor antagonist family
DYQ48_RS15475	COG1902	pentaerythritol trinitrate reductase activity
DYQ48_RS15490	COG0326	Molecular chaperone. Has ATPase activity
DYQ48_RS15495	COG2207	Transcriptional regulator
DYQ48_RS15505	COG3152	Membrane
DYQ48_RS15520	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DYQ48_RS15525	COG1845	cytochrome c oxidase, subunit III
DYQ48_RS15530	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DYQ48_RS15550	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DYQ48_RS15560	COG0196	riboflavin kinase activity
DYQ48_RS15575	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DYQ48_RS15580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DYQ48_RS15590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DYQ48_RS15595	COG0824	Thioesterase
DYQ48_RS15605	COG1024	Enoyl-CoA hydratase
DYQ48_RS15610	COG1946	Acyl-CoA thioesterase
DYQ48_RS15620	COG1595	DNA-templated transcription, initiation
DYQ48_RS15640	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DYQ48_RS15690	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DYQ48_RS15705	COG2197	response regulator
DYQ48_RS15710	COG4585	Histidine kinase
DYQ48_RS15730	COG2894	cell division
DYQ48_RS15735	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DYQ48_RS15745	COG5002	protein histidine kinase activity
DYQ48_RS15750	COG0745	RESPONSE REGULATOR receiver
DYQ48_RS15765	COG2194	sulfuric ester hydrolase activity
DYQ48_RS15790	COG2814	Major facilitator Superfamily
DYQ48_RS15795	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DYQ48_RS15795	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DYQ48_RS15805	COG0656	L-ascorbic acid biosynthetic process
DYQ48_RS15815	COG0753	catalase activity
DYQ48_RS15825	COG2207	Transcriptional regulator
DYQ48_RS15825	COG1917	Cupin 2, conserved barrel domain protein
DYQ48_RS15835	COG0823	Involved in the tonB-independent uptake of proteins
DYQ48_RS15835	COG1506	peptidase
DYQ48_RS15845	COG1297	OPT oligopeptide transporter protein
DYQ48_RS15855	COG0587	DNA-directed DNA polymerase activity
DYQ48_RS15910	COG2080	2 iron, 2 sulfur cluster binding
DYQ48_RS15915	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DYQ48_RS15920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DYQ48_RS15970	COG3537	Alpha-1,2-mannosidase
DYQ48_RS15980	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS15995	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DYQ48_RS16070	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DYQ48_RS16090	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DYQ48_RS16140	COG0330	HflC and HflK could
DYQ48_RS16145	COG0330	HflC and HflK could
DYQ48_RS16165	COG0678	peroxiredoxin activity
DYQ48_RS16175	COG4953	penicillin-binding protein 1C
DYQ48_RS16195	COG2373	Large extracellular alpha-helical protein
DYQ48_RS16230	COG3829	transcription factor binding
DYQ48_RS16240	COG2161	toxin-antitoxin pair type II binding
DYQ48_RS16245	COG4115	mRNA cleavage
DYQ48_RS16265	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DYQ48_RS16270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DYQ48_RS16290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DYQ48_RS16300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DYQ48_RS16305	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DYQ48_RS16310	COG1399	metal-binding, possibly nucleic acid-binding protein
DYQ48_RS16330	COG0714	Associated with various cellular activities
DYQ48_RS16350	COG0537	adenosine 5'-monophosphoramidase activity
DYQ48_RS16360	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DYQ48_RS16500	COG0314	molybdopterin synthase activity
DYQ48_RS16505	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DYQ48_RS16510	COG0315	cyclic pyranopterin monophosphate synthase activity
DYQ48_RS16515	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DYQ48_RS16520	COG1234	tRNA 3'-trailer cleavage
DYQ48_RS16530	COG0859	PFAM glycosyl transferase family 9
DYQ48_RS16545	COG0631	protein serine/threonine phosphatase activity
DYQ48_RS16565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYQ48_RS16575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DYQ48_RS16605	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DYQ48_RS16615	COG0544	peptidyl-prolyl cis-trans isomerase activity
DYQ48_RS16665	COG4695	Portal protein
DYQ48_RS16940	COG0473	3-isopropylmalate dehydrogenase activity
DYQ48_RS16955	COG4783	chaperone-mediated protein folding
DYQ48_RS16960	COG0745	RESPONSE REGULATOR receiver
DYQ48_RS16970	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DYQ48_RS16980	COG0438	transferase activity, transferring glycosyl groups
DYQ48_RS16985	COG0671	phosphoesterase, PA-phosphatase related
DYQ48_RS16990	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DYQ48_RS17000	COG3291	Pkd domain containing protein
DYQ48_RS17005	COG2833	Protein of unknown function (DUF455)
DYQ48_RS17025	COG0285	dihydrofolate synthase activity
DYQ48_RS17035	COG0406	alpha-ribazole phosphatase activity
DYQ48_RS17060	COG1063	alcohol dehydrogenase
DYQ48_RS17075	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DYQ48_RS17080	COG4208	sulfate ABC transporter
DYQ48_RS17085	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DYQ48_RS17090	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DYQ48_RS17095	COG0156	8-amino-7-oxononanoate synthase activity
DYQ48_RS17115	COG2885	chlorophyll binding
DYQ48_RS17125	COG0604	alcohol dehydrogenase
DYQ48_RS17130	COG0446	pyridine nucleotide-disulphide oxidoreductase
DYQ48_RS17130	COG1902	pentaerythritol trinitrate reductase activity
DYQ48_RS17145	COG0625	glutathione transferase activity
DYQ48_RS17155	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DYQ48_RS17160	COG1217	gtp-binding protein TYPA
DYQ48_RS17170	COG0154	amidase activity
DYQ48_RS17180	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DYQ48_RS17190	COG0203	ribosomal protein L17
DYQ48_RS17215	COG0201	protein transport
DYQ48_RS17260	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DYQ48_RS17270	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DYQ48_RS17275	COG0255	Belongs to the universal ribosomal protein uL29 family
DYQ48_RS17290	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DYQ48_RS17300	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DYQ48_RS17320	COG0051	transcription antitermination factor activity, RNA binding
DYQ48_RS17325	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DYQ48_RS17340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DYQ48_RS17345	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DYQ48_RS17355	COG0222	ribosome binding
DYQ48_RS17360	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DYQ48_RS17365	COG0081	regulation of translation
DYQ48_RS17370	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DYQ48_RS17375	COG0250	Participates in transcription elongation, termination and antitermination
DYQ48_RS17455	COG0582	viral genome integration into host DNA
DYQ48_RS17460	COG0012	GTP binding
DYQ48_RS17465	COG0193	aminoacyl-tRNA hydrolase activity
DYQ48_RS17470	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DYQ48_RS17475	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DYQ48_RS17490	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DYQ48_RS17500	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DYQ48_RS17520	COG0521	Mo-molybdopterin cofactor biosynthetic process
DYQ48_RS17540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DYQ48_RS17545	COG1295	ribonuclease BN
DYQ48_RS17570	COG1404	Belongs to the peptidase S8 family
DYQ48_RS17580	COG1404	Belongs to the peptidase S8 family
DYQ48_RS17585	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DYQ48_RS17635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DYQ48_RS17635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DYQ48_RS17655	COG2890	protein-(glutamine-N5) methyltransferase activity
DYQ48_RS17665	COG3634	alkyl hydroperoxide reductase activity
DYQ48_RS17670	COG0583	DNA-binding transcription factor activity
DYQ48_RS17675	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DYQ48_RS17680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DYQ48_RS17690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DYQ48_RS17700	COG2197	response regulator
DYQ48_RS17705	COG5002	protein histidine kinase activity
DYQ48_RS17705	COG2205	protein histidine kinase activity
DYQ48_RS17705	COG0784	Response regulator, receiver
DYQ48_RS17725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DYQ48_RS17730	COG0697	spore germination
DYQ48_RS17755	COG3386	PFAM SMP-30 Gluconolaconase
DYQ48_RS17775	COG1024	Enoyl-CoA hydratase
DYQ48_RS17785	COG0318	PFAM AMP-dependent synthetase and ligase
DYQ48_RS17790	COG0583	DNA-binding transcription factor activity
DYQ48_RS17795	COG3384	dioxygenase
DYQ48_RS17825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DYQ48_RS17830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DYQ48_RS17840	COG2096	Adenosyltransferase
DYQ48_RS17845	COG0123	including yeast histone deacetylase and acetoin utilization protein
DYQ48_RS17850	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DYQ48_RS17865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DYQ48_RS17870	COG2967	ApaG domain
DYQ48_RS17875	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DYQ48_RS17880	COG0431	NADPH-dependent FMN reductase
DYQ48_RS17885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DYQ48_RS17895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DYQ48_RS17900	COG1116	anion transmembrane transporter activity
DYQ48_RS17920	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DYQ48_RS17940	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DYQ48_RS17950	COG0642	Histidine kinase
DYQ48_RS17965	COG4181	ATPase activity
DYQ48_RS17975	COG2175	clavaminate synthase activity
DYQ48_RS17985	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DYQ48_RS17990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DYQ48_RS18055	COG4771	TonB-dependent receptor
DYQ48_RS18065	COG0667	Aldo Keto reductase
DYQ48_RS18070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DYQ48_RS18085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DYQ48_RS18090	COG4106	trans-aconitate 2-methyltransferase activity
DYQ48_RS18100	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DYQ48_RS18115	COG2885	chlorophyll binding
DYQ48_RS18135	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DYQ48_RS18200	COG3321	synthase
DYQ48_RS18200	COG0604	alcohol dehydrogenase
DYQ48_RS18200	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS18210	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DYQ48_RS18230	COG0494	nUDIX hydrolase
DYQ48_RS18240	COG0653	protein targeting
DYQ48_RS18245	COG0739	heme binding
DYQ48_RS18275	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DYQ48_RS18280	COG1181	Belongs to the D-alanine--D-alanine ligase family
DYQ48_RS18285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DYQ48_RS18305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DYQ48_RS18310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DYQ48_RS18320	COG3116	cell division
DYQ48_RS18365	COG0792	nuclease activity
DYQ48_RS18370	COG1988	membrane-bound metal-dependent
DYQ48_RS18375	COG0277	FAD linked oxidase domain protein
DYQ48_RS18380	COG0745	RESPONSE REGULATOR receiver
DYQ48_RS18385	COG2205	protein histidine kinase activity
DYQ48_RS18395	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DYQ48_RS18400	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DYQ48_RS18430	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DYQ48_RS18470	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DYQ48_RS18470	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DYQ48_RS18485	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DYQ48_RS18495	COG0488	(ABC) transporter
DYQ48_RS18500	COG0242	peptide deformylase activity
DYQ48_RS18515	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DYQ48_RS18560	COG2188	Transcriptional regulator
DYQ48_RS18600	COG1450	Type ii and iii secretion system protein
DYQ48_RS18615	COG3166	PFAM Fimbrial assembly family protein
DYQ48_RS18620	COG3156	type II secretion system protein K
DYQ48_RS18625	COG4795	General secretion pathway protein
DYQ48_RS18630	COG2165	general secretion pathway protein
DYQ48_RS18635	COG4970	Tfp pilus assembly protein FimT
DYQ48_RS18640	COG2165	general secretion pathway protein
DYQ48_RS18645	COG1459	type II secretion system
DYQ48_RS18650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DYQ48_RS18655	COG1404	Belongs to the peptidase S8 family
DYQ48_RS18660	COG5295	Hep Hag repeat protein
DYQ48_RS18670	COG1404	Belongs to the peptidase S8 family
DYQ48_RS18680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DYQ48_RS18680	COG0047	phosphoribosylformylglycinamidine synthase activity
DYQ48_RS18685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DYQ48_RS18690	COG4974	Belongs to the 'phage' integrase family
DYQ48_RS18705	COG0795	lipopolysaccharide-transporting ATPase activity
DYQ48_RS18725	COG0525	valine-tRNA ligase activity
DYQ48_RS18750	COG1183	phosphatidylcholine synthase activity
DYQ48_RS18760	COG0442	prolyl-tRNA aminoacylation
DYQ48_RS18775	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DYQ48_RS18780	COG1127	ABC transporter
DYQ48_RS18785	COG3218	ABC-type transport auxiliary lipoprotein component
DYQ48_RS18785	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DYQ48_RS18830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DYQ48_RS18835	COG0662	Cupin 2, conserved barrel domain protein
DYQ48_RS18835	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DYQ48_RS18860	COG2086	electron transfer activity
DYQ48_RS18880	COG0463	Glycosyl transferase, family 2
DYQ48_RS18905	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DYQ48_RS18945	COG0626	cystathionine gamma-synthase activity
DYQ48_RS18975	COG0625	glutathione transferase activity
DYQ48_RS18990	COG0513	Belongs to the DEAD box helicase family
DYQ48_RS19000	COG4771	TonB-dependent receptor
DYQ48_RS19005	COG0720	synthase
DYQ48_RS19015	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DYQ48_RS19020	COG1956	GAF domain-containing protein
DYQ48_RS19030	COG2819	hydrolase of the alpha beta superfamily
DYQ48_RS19050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DYQ48_RS19065	COG0339	signal peptide processing
DYQ48_RS19110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DYQ48_RS19115	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DYQ48_RS19125	COG1136	(ABC) transporter
DYQ48_RS19135	COG0577	efflux transmembrane transporter activity
DYQ48_RS19145	COG4191	Histidine kinase
DYQ48_RS19155	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DYQ48_RS19170	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DYQ48_RS19195	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DYQ48_RS19205	COG0356	it plays a direct role in the translocation of protons across the membrane
DYQ48_RS19220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DYQ48_RS19230	COG0508	dehydrogenase complex catalyzes the overall conversion of
DYQ48_RS19260	COG2011	ABC-type metal ion transport system permease component
DYQ48_RS19265	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DYQ48_RS19270	COG0697	spore germination
DYQ48_RS19295	COG1187	pseudouridine synthase activity
DYQ48_RS19300	COG2813	Specifically methylates the guanine in position
DYQ48_RS19325	COG2205	protein histidine kinase activity
DYQ48_RS19325	COG0784	Response regulator, receiver
DYQ48_RS19325	COG2198	Histidine kinase
DYQ48_RS19325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYQ48_RS19345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DYQ48_RS19350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DYQ48_RS19410	COG3039	Transposase
DYQ48_RS19465	COG0842	Transport permease protein
DYQ48_RS19470	COG1131	(ABC) transporter
DYQ48_RS19480	COG0025	NhaP-type Na H and K H
DYQ48_RS19490	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DYQ48_RS19495	COG1573	uracil-dna glycosylase
DYQ48_RS19510	COG3384	dioxygenase
DYQ48_RS19520	COG0583	DNA-binding transcription factor activity
DYQ48_RS19530	COG0667	Aldo Keto reductase
DYQ48_RS19540	COG3590	peptidase
DYQ48_RS19560	COG0531	amino acid
DYQ48_RS19575	COG2972	Histidine kinase
DYQ48_RS19595	COG3685	Protein conserved in bacteria
DYQ48_RS19600	COG3546	catalase activity
DYQ48_RS19625	COG2204	response regulator
DYQ48_RS19640	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS19650	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DYQ48_RS19670	COG1132	(ABC) transporter
DYQ48_RS19685	COG1063	alcohol dehydrogenase
DYQ48_RS19705	COG0583	DNA-binding transcription factor activity
DYQ48_RS19710	COG2814	Major facilitator Superfamily
DYQ48_RS19750	COG1131	(ABC) transporter
DYQ48_RS19765	COG0251	oxidation-reduction process
DYQ48_RS19790	COG0659	secondary active sulfate transmembrane transporter activity
DYQ48_RS19810	COG4977	sequence-specific DNA binding
DYQ48_RS19825	COG1309	transcriptional regulator
DYQ48_RS19830	COG0583	DNA-binding transcription factor activity
DYQ48_RS19835	COG1902	pentaerythritol trinitrate reductase activity
DYQ48_RS19855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DYQ48_RS19860	COG1490	D-aminoacyl-tRNA deacylase activity
DYQ48_RS19865	COG1560	Kdo2-lipid A biosynthetic process
DYQ48_RS19915	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DYQ48_RS19915	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DYQ48_RS19920	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DYQ48_RS19925	COG0242	peptide deformylase activity
DYQ48_RS19930	COG1652	LysM domain
DYQ48_RS19935	COG0758	DNA mediated transformation
DYQ48_RS19955	COG1754	DNA topoisomerase type I activity
DYQ48_RS19955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DYQ48_RS19960	COG0009	L-threonylcarbamoyladenylate synthase
DYQ48_RS19975	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS19985	COG0616	signal peptide processing
DYQ48_RS19990	COG0534	Mate efflux family protein
DYQ48_RS20005	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DYQ48_RS20015	COG0625	glutathione transferase activity
DYQ48_RS20035	COG1252	NADH dehydrogenase
DYQ48_RS20040	COG2860	membrane
DYQ48_RS20045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DYQ48_RS20050	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DYQ48_RS20055	COG3437	response regulator, receiver
DYQ48_RS20060	COG2177	Part of the ABC transporter FtsEX involved in
DYQ48_RS20065	COG2884	Cell division ATP-binding protein ftsE
DYQ48_RS20075	COG3118	belongs to the thioredoxin family
DYQ48_RS20080	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DYQ48_RS20100	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
DYQ48_RS20130	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DYQ48_RS20130	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DYQ48_RS20135	COG1473	amidohydrolase
DYQ48_RS20140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYQ48_RS20145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYQ48_RS20160	COG4948	Mandelate Racemase Muconate Lactonizing
DYQ48_RS20170	COG3023	N-Acetylmuramoyl-L-alanine amidase
DYQ48_RS20175	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DYQ48_RS20215	COG5383	Protein conserved in bacteria
DYQ48_RS20235	COG0531	amino acid
DYQ48_RS20250	COG4682	membrane
DYQ48_RS20255	COG2133	pyrroloquinoline quinone binding
DYQ48_RS20270	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DYQ48_RS20285	COG1610	YqeY-like protein
DYQ48_RS20290	COG1295	ribonuclease BN
DYQ48_RS20295	COG0358	DNA primase activity
DYQ48_RS20310	COG0109	protoheme IX farnesyltransferase activity
DYQ48_RS20340	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DYQ48_RS20355	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DYQ48_RS20400	COG0739	heme binding
DYQ48_RS20415	COG2807	transmembrane transport
DYQ48_RS20420	COG0708	Exodeoxyribonuclease III
DYQ48_RS20435	COG1192	Involved in chromosome partitioning
DYQ48_RS20440	COG1475	DNA binding
DYQ48_RS20455	COG0463	Glycosyl transferase, family 2
DYQ48_RS20475	COG0756	dUTP diphosphatase activity
DYQ48_RS20480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DYQ48_RS20490	COG0018	arginyl-trna synthetase
DYQ48_RS20500	COG4221	oxidoreductase activity
DYQ48_RS20505	COG2755	lipolytic protein G-D-S-L family
DYQ48_RS20505	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DYQ48_RS20515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DYQ48_RS20520	COG1166	arginine decarboxylase activity
DYQ48_RS20555	COG2960	long-chain fatty acid transporting porin activity
DYQ48_RS20560	COG0606	chelatase, subunit chli
DYQ48_RS20580	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DYQ48_RS20630	COG1090	epimerase
DYQ48_RS20640	COG0642	Histidine kinase
DYQ48_RS20660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DYQ48_RS20685	COG1011	Hydrolase
DYQ48_RS20690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DYQ48_RS20715	COG2197	response regulator
DYQ48_RS20720	COG4585	Histidine kinase
DYQ48_RS20725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYQ48_RS20730	COG1136	(ABC) transporter
DYQ48_RS20755	COG0697	spore germination
DYQ48_RS20785	COG0180	Tryptophanyl-tRNA synthetase
DYQ48_RS20790	COG3237	CsbD-like
DYQ48_RS20835	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DYQ48_RS20850	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DYQ48_RS20855	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DYQ48_RS20855	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DYQ48_RS20865	COG3228	Belongs to the MtfA family
DYQ48_RS20895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DYQ48_RS20920	COG1199	ATP-dependent helicase activity
DYQ48_RS20955	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DYQ48_RS21000	COG0625	glutathione transferase activity
DYQ48_RS21035	COG4555	ABC transporter
DYQ48_RS21045	COG1476	TRANSCRIPTIONal
DYQ48_RS21075	COG1131	(ABC) transporter
DYQ48_RS21080	COG0842	Transport permease protein
DYQ48_RS21090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DYQ48_RS21110	COG1607	acyl-coa hydrolase
DYQ48_RS21125	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DYQ48_RS21135	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DYQ48_RS21150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DYQ48_RS21150	COG1042	CoA-binding domain protein
DYQ48_RS21150	COG0045	succinate-CoA ligase (ADP-forming) activity
DYQ48_RS21165	COG4771	TonB-dependent receptor
DYQ48_RS21165	COG1629	transport
DYQ48_RS21170	COG2239	Acts as a magnesium transporter
DYQ48_RS21185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DYQ48_RS21190	COG3387	PFAM Glycoside hydrolase 15-related
DYQ48_RS21205	COG3100	YcgL domain-containing protein
DYQ48_RS21210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DYQ48_RS21250	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS21275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DYQ48_RS21290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DYQ48_RS21335	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DYQ48_RS21335	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DYQ48_RS21365	COG3621	Patatin-like phospholipase
DYQ48_RS21390	COG0210	DNA helicase
DYQ48_RS21400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DYQ48_RS21410	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DYQ48_RS21420	COG2159	amidohydrolase
DYQ48_RS21440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYQ48_RS21470	COG3540	Alkaline phosphatase
DYQ48_RS21480	COG2091	lysine biosynthetic process via aminoadipic acid
DYQ48_RS21495	COG0708	Exodeoxyribonuclease III
DYQ48_RS21510	COG1940	carbohydrate kinase activity
DYQ48_RS21520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DYQ48_RS21530	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DYQ48_RS21535	COG3162	membrane
DYQ48_RS21600	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS21605	COG0179	Fumarylacetoacetate (FAA) hydrolase
DYQ48_RS21610	COG4948	Mandelate Racemase Muconate Lactonizing
DYQ48_RS21620	COG3254	rhamnose metabolic process
DYQ48_RS21625	COG0738	Major facilitator superfamily
DYQ48_RS21630	COG1414	Transcriptional regulator
DYQ48_RS21645	COG1971	Probably functions as a manganese efflux pump
DYQ48_RS21650	COG2205	protein histidine kinase activity
DYQ48_RS21660	COG3459	Glycosyltransferase 36 associated
DYQ48_RS21665	COG2211	Major facilitator Superfamily
DYQ48_RS21670	COG3265	gluconokinase activity
DYQ48_RS21675	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DYQ48_RS21695	COG3039	Transposase
DYQ48_RS21715	COG2911	Protein conserved in bacteria
DYQ48_RS21720	COG0729	surface antigen
DYQ48_RS21735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DYQ48_RS21750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DYQ48_RS21750	COG0519	Catalyzes the synthesis of GMP from XMP
DYQ48_RS21760	COG0805	protein transport
DYQ48_RS21765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DYQ48_RS21770	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DYQ48_RS21780	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DYQ48_RS21795	COG2974	May be involved in recombination
DYQ48_RS21800	COG0037	tRNA processing
DYQ48_RS21810	COG2115	Belongs to the xylose isomerase family
DYQ48_RS21820	COG3661	Belongs to the glycosyl hydrolase 67 family
DYQ48_RS21830	COG4948	Mandelate Racemase Muconate Lactonizing
DYQ48_RS21840	COG1472	Belongs to the glycosyl hydrolase 3 family
DYQ48_RS21845	COG0246	Mannitol dehydrogenase
DYQ48_RS21870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DYQ48_RS21875	COG1620	l-lactate permease
DYQ48_RS21885	COG3386	PFAM SMP-30 Gluconolaconase
DYQ48_RS21895	COG3250	beta-galactosidase activity
DYQ48_RS21900	COG1904	glucuronate isomerase
DYQ48_RS21905	COG3693	PFAM glycoside hydrolase, family 10
DYQ48_RS21920	COG2211	Major facilitator Superfamily
DYQ48_RS21980	COG2937	Belongs to the GPAT DAPAT family
DYQ48_RS22005	COG0284	orotidine-5'-phosphate decarboxylase activity
DYQ48_RS22010	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DYQ48_RS22015	COG3132	Protein of unknown function, DUF480
DYQ48_RS22035	COG0210	DNA helicase
DYQ48_RS22040	COG1435	thymidine kinase activity
DYQ48_RS22050	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
DYQ48_RS22060	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DYQ48_RS22090	COG3135	benzoate transporter
DYQ48_RS22110	COG0676	glucose-6-phosphate 1-epimerase activity
DYQ48_RS22125	COG0730	response to heat
DYQ48_RS22155	COG0302	gtp cyclohydrolase
DYQ48_RS22170	COG1566	PFAM secretion protein HlyD family protein
DYQ48_RS22180	COG1289	transmembrane transporter activity
DYQ48_RS22185	COG0477	Major facilitator Superfamily
DYQ48_RS22190	COG0583	DNA-binding transcription factor activity
DYQ48_RS22195	COG4221	oxidoreductase activity
DYQ48_RS22205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DYQ48_RS22235	COG1192	Involved in chromosome partitioning
DYQ48_RS22250	COG3550	peptidyl-serine autophosphorylation
DYQ48_RS22345	COG2207	Transcriptional regulator
DYQ48_RS22350	COG1028	Short-chain dehydrogenase reductase Sdr
DYQ48_RS22360	COG3549	Plasmid maintenance system killer
DYQ48_RS22370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DYQ48_RS22375	COG1074	ATP-dependent DNA helicase activity
DYQ48_RS22380	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DYQ48_RS22385	COG1127	ABC transporter
DYQ48_RS22390	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DYQ48_RS22395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DYQ48_RS22410	COG2853	Lipoprotein
DYQ48_RS22440	COG0386	Belongs to the glutathione peroxidase family
DYQ48_RS22450	COG1322	Protein conserved in bacteria
DYQ48_RS22455	COG0625	glutathione transferase activity
DYQ48_RS22460	COG0531	amino acid
DYQ48_RS22465	COG3537	Alpha-1,2-mannosidase
DYQ48_RS22480	COG2199	diguanylate cyclase activity
DYQ48_RS22480	COG2203	Gaf domain
DYQ48_RS22485	COG3835	regulator
DYQ48_RS22490	COG1929	Belongs to the glycerate kinase type-1 family
DYQ48_RS22495	COG2271	Major facilitator Superfamily
DYQ48_RS22530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYQ48_RS22535	COG1126	abc transporter atp-binding protein
DYQ48_RS22545	COG1473	amidohydrolase
DYQ48_RS22550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DYQ48_RS22555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DYQ48_RS22565	COG4206	TonB-dependent receptor
DYQ48_RS22585	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DYQ48_RS22595	COG0861	Integral membrane protein TerC family
DYQ48_RS22605	COG0584	glycerophosphoryl diester phosphodiesterase
DYQ48_RS22630	COG0706	membrane insertase activity
DYQ48_RS22685	COG5599	Phosphatase
DYQ48_RS22825	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DYQ48_RS22935	COG0653	protein targeting