locus-tag	class	description
NDY25_RS00055	COG0653	protein targeting
NDY25_RS00070	COG2154	pterin-4-alpha-carbinolamine dehydratase
NDY25_RS00080	COG0428	transporter
NDY25_RS00100	COG1054	Belongs to the UPF0176 family
NDY25_RS00120	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NDY25_RS00170	COG1304	FMN binding
NDY25_RS00175	COG1247	-acetyltransferase
NDY25_RS00190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NDY25_RS00195	COG0322	excinuclease ABC activity
NDY25_RS00205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NDY25_RS00210	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NDY25_RS00215	COG1663	tetraacyldisaccharide 4'-kinase activity
NDY25_RS00220	COG1132	(ABC) transporter
NDY25_RS00230	COG0811	peptide transport
NDY25_RS00245	COG1136	(ABC) transporter
NDY25_RS00250	COG4591	ABC-type transport system involved in lipoprotein release permease component
NDY25_RS00260	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NDY25_RS00265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NDY25_RS00280	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NDY25_RS00285	COG2009	succinate dehydrogenase
NDY25_RS00305	COG0837	glucose binding
NDY25_RS00310	COG0363	glucosamine-6-phosphate deaminase activity
NDY25_RS00315	COG0129	dihydroxy-acid dehydratase activity
NDY25_RS00320	COG0800	Aldolase
NDY25_RS00385	COG0784	Response regulator, receiver
NDY25_RS00385	COG2205	protein histidine kinase activity
NDY25_RS00385	COG5002	protein histidine kinase activity
NDY25_RS00390	COG2183	response to ionizing radiation
NDY25_RS00415	COG3243	poly(R)-hydroxyalkanoic acid synthase
NDY25_RS00425	COG1183	phosphatidylcholine synthase activity
NDY25_RS00455	COG0668	transmembrane transport
NDY25_RS00460	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NDY25_RS00475	COG1914	H( )-stimulated, divalent metal cation uptake system
NDY25_RS00505	COG2814	Major facilitator Superfamily
NDY25_RS00520	COG1335	isochorismatase
NDY25_RS00535	COG2197	response regulator
NDY25_RS00580	COG0583	DNA-binding transcription factor activity
NDY25_RS00600	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NDY25_RS00605	COG0077	Prephenate dehydratase
NDY25_RS00605	COG1605	Chorismate mutase
NDY25_RS00610	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NDY25_RS00615	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NDY25_RS00620	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NDY25_RS00655	COG1228	amidohydrolase
NDY25_RS00660	COG2986	histidine ammonia-lyase
NDY25_RS00670	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NDY25_RS00700	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NDY25_RS00710	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NDY25_RS00715	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NDY25_RS00720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NDY25_RS00725	COG3115	cell septum assembly
NDY25_RS00750	COG0316	Belongs to the HesB IscA family
NDY25_RS00755	COG0017	Asparaginyl-tRNA synthetase
NDY25_RS00770	COG2808	Putative FMN-binding domain
NDY25_RS00775	COG0288	reversible hydration of carbon dioxide
NDY25_RS00795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDY25_RS00800	COG2925	Exonuclease
NDY25_RS00825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NDY25_RS00840	COG0488	(ABC) transporter
NDY25_RS00890	COG1024	Enoyl-CoA hydratase
NDY25_RS00900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NDY25_RS00905	COG0659	secondary active sulfate transmembrane transporter activity
NDY25_RS00930	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NDY25_RS00935	COG0573	inorganic phosphate transmembrane transporter activity
NDY25_RS00940	COG0581	inorganic phosphate transmembrane transporter activity
NDY25_RS00950	COG0704	Plays a role in the regulation of phosphate uptake
NDY25_RS00960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NDY25_RS00970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NDY25_RS00980	COG0557	exoribonuclease II activity
NDY25_RS00995	COG1960	acyl-CoA dehydrogenase activity
NDY25_RS01000	COG2226	methyltransferase
NDY25_RS01005	COG1410	methionine synthase
NDY25_RS01005	COG0646	methionine synthase
NDY25_RS01010	COG1410	methionine synthase
NDY25_RS01010	COG0646	methionine synthase
NDY25_RS01020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NDY25_RS01045	COG2900	Belongs to the SlyX family
NDY25_RS01060	COG0386	Belongs to the glutathione peroxidase family
NDY25_RS01070	COG1725	Transcriptional regulator
NDY25_RS01075	COG1131	(ABC) transporter
NDY25_RS01105	COG1253	flavin adenine dinucleotide binding
NDY25_RS01120	COG2850	peptidyl-arginine hydroxylation
NDY25_RS01155	COG1619	proteins homologs of microcin C7 resistance protein MccF
NDY25_RS01165	COG1132	(ABC) transporter
NDY25_RS01170	COG0583	DNA-binding transcription factor activity
NDY25_RS01175	COG2274	protein secretion by the type I secretion system
NDY25_RS01195	COG0287	Prephenate dehydrogenase
NDY25_RS01195	COG1605	Chorismate mutase
NDY25_RS01200	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NDY25_RS01215	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NDY25_RS01220	COG1420	regulation of RNA biosynthetic process
NDY25_RS01225	COG0497	DNA recombination
NDY25_RS01235	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NDY25_RS01250	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NDY25_RS01395	COG1611	Belongs to the LOG family
NDY25_RS01405	COG2095	MarC family integral membrane protein
NDY25_RS01410	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS01415	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NDY25_RS01460	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NDY25_RS01465	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NDY25_RS01470	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NDY25_RS01480	COG0195	Participates in both transcription termination and antitermination
NDY25_RS01485	COG0779	Required for maturation of 30S ribosomal subunits
NDY25_RS01495	COG1007	ATP synthesis coupled electron transport
NDY25_RS01515	COG0839	Belongs to the complex I subunit 6 family
NDY25_RS01525	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NDY25_RS01535	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NDY25_RS01540	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NDY25_RS01545	COG0649	NAD binding
NDY25_RS01550	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NDY25_RS01560	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NDY25_RS01580	COG4221	oxidoreductase activity
NDY25_RS01610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NDY25_RS01620	COG0159	tryptophan synthase activity
NDY25_RS01630	COG0133	tryptophan synthase activity
NDY25_RS01645	COG0101	tRNA pseudouridine synthase activity
NDY25_RS01660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NDY25_RS01665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NDY25_RS01680	COG2890	protein-(glutamine-N5) methyltransferase activity
NDY25_RS01690	COG0688	phosphatidylethanolamine metabolic process
NDY25_RS01700	COG0433	COG0433 Predicted ATPase
NDY25_RS01710	COG0494	nUDIX hydrolase
NDY25_RS01755	COG0717	Belongs to the dCTP deaminase family
NDY25_RS01760	COG0489	protein tyrosine kinase activity
NDY25_RS01780	COG3590	peptidase
NDY25_RS01785	COG3590	peptidase
NDY25_RS01805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NDY25_RS01815	COG2311	Membrane
NDY25_RS01820	COG1047	Peptidyl-prolyl cis-trans
NDY25_RS01830	COG0791	NLP P60 protein
NDY25_RS01860	COG4191	Histidine kinase
NDY25_RS01875	COG1301	dicarboxylic acid transport
NDY25_RS01880	COG1785	Belongs to the alkaline phosphatase family
NDY25_RS01885	COG0037	tRNA processing
NDY25_RS01890	COG1722	exodeoxyribonuclease VII activity
NDY25_RS01895	COG0142	geranyltranstransferase activity
NDY25_RS01910	COG0312	modulator of DNA gyrase
NDY25_RS01920	COG0312	modulator of DNA gyrase
NDY25_RS01930	COG3164	Protein of unknown function
NDY25_RS01955	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NDY25_RS01975	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NDY25_RS01990	COG0495	leucyl-tRNA aminoacylation
NDY25_RS02000	COG3118	belongs to the thioredoxin family
NDY25_RS02010	COG2155	Conserved Protein
NDY25_RS02050	COG1132	(ABC) transporter
NDY25_RS02060	COG0475	glutathione-regulated potassium exporter activity
NDY25_RS02070	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NDY25_RS02090	COG1187	pseudouridine synthase activity
NDY25_RS02095	COG5002	protein histidine kinase activity
NDY25_RS02095	COG5001	Diguanylate cyclase
NDY25_RS02105	COG1595	DNA-templated transcription, initiation
NDY25_RS02220	COG0667	Aldo Keto reductase
NDY25_RS02225	COG2814	Major facilitator Superfamily
NDY25_RS02230	COG0583	DNA-binding transcription factor activity
NDY25_RS02260	COG0667	Aldo Keto reductase
NDY25_RS02265	COG1309	transcriptional regulator
NDY25_RS02275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NDY25_RS02290	COG0735	belongs to the Fur family
NDY25_RS02295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NDY25_RS02320	COG4452	Inner membrane protein CreD
NDY25_RS02325	COG2205	protein histidine kinase activity
NDY25_RS02330	COG0745	RESPONSE REGULATOR receiver
NDY25_RS02340	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NDY25_RS02350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NDY25_RS02405	COG2198	Histidine kinase
NDY25_RS02405	COG0643	Histidine kinase
NDY25_RS02410	COG0840	transmembrane signaling receptor activity
NDY25_RS02415	COG0835	chemotaxis
NDY25_RS02420	COG2202	Pas domain
NDY25_RS02420	COG2200	EAL domain
NDY25_RS02420	COG2199	diguanylate cyclase activity
NDY25_RS02425	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NDY25_RS02435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDY25_RS02440	COG3590	peptidase
NDY25_RS02450	COG0588	phosphoglycerate mutase activity
NDY25_RS02455	COG1515	deoxyribonuclease V activity
NDY25_RS02460	COG1741	Belongs to the pirin family
NDY25_RS02475	COG1741	Belongs to the pirin family
NDY25_RS02480	COG1966	Carbon starvation protein
NDY25_RS02485	COG2879	small protein
NDY25_RS02490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NDY25_RS02520	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NDY25_RS02525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NDY25_RS02530	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NDY25_RS02535	COG2080	2 iron, 2 sulfur cluster binding
NDY25_RS02540	COG4251	negative regulation of phosphorylation
NDY25_RS02540	COG2203	Gaf domain
NDY25_RS02540	COG3706	GGDEF domain
NDY25_RS02540	COG5001	Diguanylate cyclase
NDY25_RS02555	COG0629	single-stranded DNA binding
NDY25_RS02560	COG0142	geranyltranstransferase activity
NDY25_RS02580	COG0527	aspartate kinase activity
NDY25_RS02585	COG0384	phenazine biosynthesis protein PhzF
NDY25_RS02590	COG0384	phenazine biosynthesis protein PhzF
NDY25_RS02600	COG1764	response to oxidative stress
NDY25_RS02610	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NDY25_RS02615	COG1678	Uncharacterized ACR, COG1678
NDY25_RS02620	COG0519	Catalyzes the synthesis of GMP from XMP
NDY25_RS02640	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NDY25_RS02655	COG4942	peptidase
NDY25_RS02680	COG1959	2 iron, 2 sulfur cluster binding
NDY25_RS02685	COG0719	Fe-S assembly protein
NDY25_RS02690	COG0396	ATPase activity
NDY25_RS02695	COG0719	Fe-S assembly protein
NDY25_RS02700	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NDY25_RS02715	COG4774	siderophore transport
NDY25_RS02720	COG3128	pkhd-type hydroxylase
NDY25_RS02745	COG1477	protein flavinylation
NDY25_RS02760	COG1555	photosystem II stabilization
NDY25_RS02775	COG3178	'Phosphotransferase
NDY25_RS02800	COG0288	reversible hydration of carbon dioxide
NDY25_RS02825	COG0386	Belongs to the glutathione peroxidase family
NDY25_RS02830	COG0339	signal peptide processing
NDY25_RS02885	COG2814	Major facilitator Superfamily
NDY25_RS02890	COG1566	PFAM secretion protein HlyD family protein
NDY25_RS02935	COG4774	siderophore transport
NDY25_RS02945	COG0367	asparagine synthase
NDY25_RS02955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NDY25_RS02960	COG1393	Belongs to the ArsC family
NDY25_RS02975	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NDY25_RS03020	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NDY25_RS03030	COG0528	UMP kinase activity
NDY25_RS03040	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NDY25_RS03045	COG0575	Belongs to the CDS family
NDY25_RS03050	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NDY25_RS03055	COG0750	zinc metalloprotease
NDY25_RS03070	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NDY25_RS03075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NDY25_RS03080	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NDY25_RS03085	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NDY25_RS03100	COG0825	malonyl-CoA metabolic process
NDY25_RS03110	COG1981	membrane
NDY25_RS03130	COG1695	Transcriptional regulator
NDY25_RS03155	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NDY25_RS03175	COG2040	homocysteine
NDY25_RS03180	COG0833	amino acid
NDY25_RS03185	COG0346	lactoylglutathione lyase activity
NDY25_RS03190	COG1131	(ABC) transporter
NDY25_RS03205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDY25_RS03205	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDY25_RS03215	COG2878	Part of a membrane complex involved in electron transport
NDY25_RS03230	COG1595	DNA-templated transcription, initiation
NDY25_RS03255	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NDY25_RS03270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NDY25_RS03275	COG0251	oxidation-reduction process
NDY25_RS03285	COG0392	lysyltransferase activity
NDY25_RS03285	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NDY25_RS03320	COG2814	Major facilitator Superfamily
NDY25_RS03325	COG1902	pentaerythritol trinitrate reductase activity
NDY25_RS03340	COG2824	Alkylphosphonate utilization operon protein PhnA
NDY25_RS03350	COG1047	Peptidyl-prolyl cis-trans
NDY25_RS03390	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NDY25_RS03400	COG5487	UPF0391 membrane protein
NDY25_RS03405	COG1451	nucleotide metabolic process
NDY25_RS03425	COG0183	Belongs to the thiolase family
NDY25_RS03455	COG1793	dna ligase
NDY25_RS03455	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NDY25_RS03465	COG1793	dna ligase
NDY25_RS03470	COG1201	RNA secondary structure unwinding
NDY25_RS03480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDY25_RS03485	COG1278	Cold shock
NDY25_RS03490	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NDY25_RS03495	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NDY25_RS03500	COG1472	Belongs to the glycosyl hydrolase 3 family
NDY25_RS03505	COG3046	protein related to deoxyribodipyrimidine photolyase
NDY25_RS03510	COG1233	COG1233 Phytoene dehydrogenase and related
NDY25_RS03515	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NDY25_RS03520	COG2954	triphosphatase activity
NDY25_RS03540	COG1381	Involved in DNA repair and RecF pathway recombination
NDY25_RS03545	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NDY25_RS03570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NDY25_RS03585	COG1024	Enoyl-CoA hydratase
NDY25_RS03585	COG1250	3-hydroxyacyl-CoA dehydrogenase
NDY25_RS03595	COG0457	Tetratricopeptide repeat
NDY25_RS03630	COG1024	Enoyl-CoA hydratase
NDY25_RS03635	COG1960	acyl-CoA dehydrogenase activity
NDY25_RS03655	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NDY25_RS03660	COG3250	beta-galactosidase activity
NDY25_RS03670	COG0436	Aminotransferase
NDY25_RS03685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NDY25_RS03710	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NDY25_RS03720	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NDY25_RS03730	COG0534	Mate efflux family protein
NDY25_RS03740	COG0336	Belongs to the RNA methyltransferase TrmD family
NDY25_RS03745	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NDY25_RS03775	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NDY25_RS03825	COG2205	protein histidine kinase activity
NDY25_RS03825	COG3850	Histidine kinase
NDY25_RS03825	COG3437	response regulator, receiver
NDY25_RS03825	COG4999	Histidine kinase
NDY25_RS03830	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NDY25_RS03835	COG2201	protein-glutamate methylesterase activity
NDY25_RS03840	COG2205	protein histidine kinase activity
NDY25_RS03845	COG5507	3-demethylubiquinone-9 3-methyltransferase
NDY25_RS03865	COG4771	TonB-dependent receptor
NDY25_RS03890	COG2172	sigma factor antagonist activity
NDY25_RS03895	COG1366	Belongs to the anti-sigma-factor antagonist family
NDY25_RS03900	COG1366	Belongs to the anti-sigma-factor antagonist family
NDY25_RS03905	COG1902	pentaerythritol trinitrate reductase activity
NDY25_RS03915	COG0326	Molecular chaperone. Has ATPase activity
NDY25_RS03920	COG2207	Transcriptional regulator
NDY25_RS03930	COG3152	Membrane
NDY25_RS03945	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NDY25_RS03950	COG1845	cytochrome c oxidase, subunit III
NDY25_RS03955	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NDY25_RS03975	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NDY25_RS03985	COG0196	riboflavin kinase activity
NDY25_RS04000	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NDY25_RS04005	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NDY25_RS04015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NDY25_RS04020	COG0824	Thioesterase
NDY25_RS04030	COG1024	Enoyl-CoA hydratase
NDY25_RS04035	COG1946	Acyl-CoA thioesterase
NDY25_RS04055	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NDY25_RS04105	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NDY25_RS04120	COG2197	response regulator
NDY25_RS04125	COG4585	Histidine kinase
NDY25_RS04140	COG2894	cell division
NDY25_RS04145	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NDY25_RS04155	COG5002	protein histidine kinase activity
NDY25_RS04160	COG0745	RESPONSE REGULATOR receiver
NDY25_RS04175	COG2194	sulfuric ester hydrolase activity
NDY25_RS04195	COG2814	Major facilitator Superfamily
NDY25_RS04200	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NDY25_RS04200	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NDY25_RS04210	COG0656	L-ascorbic acid biosynthetic process
NDY25_RS04220	COG0753	catalase activity
NDY25_RS04225	COG1917	Cupin 2, conserved barrel domain protein
NDY25_RS04225	COG2207	Transcriptional regulator
NDY25_RS04235	COG0823	Involved in the tonB-independent uptake of proteins
NDY25_RS04235	COG1506	peptidase
NDY25_RS04245	COG1297	OPT oligopeptide transporter protein
NDY25_RS04315	COG2080	2 iron, 2 sulfur cluster binding
NDY25_RS04320	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NDY25_RS04325	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NDY25_RS04335	COG1064	alcohol dehydrogenase
NDY25_RS04385	COG3537	Alpha-1,2-mannosidase
NDY25_RS04395	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS04405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NDY25_RS04575	COG0308	aminopeptidase N
NDY25_RS04590	COG0330	HflC and HflK could
NDY25_RS04595	COG0330	HflC and HflK could
NDY25_RS04615	COG0678	peroxiredoxin activity
NDY25_RS04625	COG4953	penicillin-binding protein 1C
NDY25_RS04655	COG2373	Large extracellular alpha-helical protein
NDY25_RS04690	COG3829	transcription factor binding
NDY25_RS04700	COG2161	toxin-antitoxin pair type II binding
NDY25_RS04705	COG4115	mRNA cleavage
NDY25_RS04725	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NDY25_RS04730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NDY25_RS04750	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NDY25_RS04760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NDY25_RS04765	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NDY25_RS04770	COG1399	metal-binding, possibly nucleic acid-binding protein
NDY25_RS04775	COG0424	maF-like protein
NDY25_RS04790	COG0714	Associated with various cellular activities
NDY25_RS04810	COG0537	adenosine 5'-monophosphoramidase activity
NDY25_RS04820	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NDY25_RS04925	COG0314	molybdopterin synthase activity
NDY25_RS04930	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NDY25_RS04935	COG0315	cyclic pyranopterin monophosphate synthase activity
NDY25_RS04940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NDY25_RS04955	COG0859	PFAM glycosyl transferase family 9
NDY25_RS04970	COG0631	protein serine/threonine phosphatase activity
NDY25_RS04990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDY25_RS05000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NDY25_RS05030	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NDY25_RS05040	COG0544	peptidyl-prolyl cis-trans isomerase activity
NDY25_RS05085	COG0473	3-isopropylmalate dehydrogenase activity
NDY25_RS05100	COG4783	chaperone-mediated protein folding
NDY25_RS05105	COG0745	RESPONSE REGULATOR receiver
NDY25_RS05115	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NDY25_RS05125	COG0438	transferase activity, transferring glycosyl groups
NDY25_RS05130	COG0671	phosphoesterase, PA-phosphatase related
NDY25_RS05135	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NDY25_RS05145	COG3291	Pkd domain containing protein
NDY25_RS05150	COG2833	Protein of unknown function (DUF455)
NDY25_RS05170	COG0285	dihydrofolate synthase activity
NDY25_RS05180	COG0406	alpha-ribazole phosphatase activity
NDY25_RS05210	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NDY25_RS05215	COG4208	sulfate ABC transporter
NDY25_RS05220	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NDY25_RS05225	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NDY25_RS05230	COG0156	8-amino-7-oxononanoate synthase activity
NDY25_RS05250	COG2885	chlorophyll binding
NDY25_RS05255	COG0604	alcohol dehydrogenase
NDY25_RS05260	COG0446	pyridine nucleotide-disulphide oxidoreductase
NDY25_RS05260	COG1902	pentaerythritol trinitrate reductase activity
NDY25_RS05280	COG0625	glutathione transferase activity
NDY25_RS05290	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NDY25_RS05295	COG1217	gtp-binding protein TYPA
NDY25_RS05305	COG0154	amidase activity
NDY25_RS05315	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NDY25_RS05325	COG0203	ribosomal protein L17
NDY25_RS05350	COG0201	protein transport
NDY25_RS05395	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NDY25_RS05405	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NDY25_RS05410	COG0255	Belongs to the universal ribosomal protein uL29 family
NDY25_RS05425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NDY25_RS05435	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NDY25_RS05455	COG0051	transcription antitermination factor activity, RNA binding
NDY25_RS05460	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NDY25_RS05475	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NDY25_RS05480	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NDY25_RS05490	COG0222	ribosome binding
NDY25_RS05495	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NDY25_RS05500	COG0081	regulation of translation
NDY25_RS05505	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NDY25_RS05510	COG0250	Participates in transcription elongation, termination and antitermination
NDY25_RS05515	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NDY25_RS05545	COG0012	GTP binding
NDY25_RS05550	COG0193	aminoacyl-tRNA hydrolase activity
NDY25_RS05555	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NDY25_RS05560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NDY25_RS05575	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NDY25_RS05585	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NDY25_RS05600	COG0521	Mo-molybdopterin cofactor biosynthetic process
NDY25_RS05620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDY25_RS05625	COG1295	ribonuclease BN
NDY25_RS05650	COG1404	Belongs to the peptidase S8 family
NDY25_RS05655	COG1404	Belongs to the peptidase S8 family
NDY25_RS05660	COG1404	Belongs to the peptidase S8 family
NDY25_RS05665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NDY25_RS05715	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NDY25_RS05715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NDY25_RS05735	COG2890	protein-(glutamine-N5) methyltransferase activity
NDY25_RS05745	COG3634	alkyl hydroperoxide reductase activity
NDY25_RS05755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NDY25_RS05760	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NDY25_RS05770	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NDY25_RS05780	COG2197	response regulator
NDY25_RS05810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NDY25_RS05815	COG0697	spore germination
NDY25_RS05845	COG3386	PFAM SMP-30 Gluconolaconase
NDY25_RS05865	COG1024	Enoyl-CoA hydratase
NDY25_RS05875	COG0318	PFAM AMP-dependent synthetase and ligase
NDY25_RS05880	COG0583	DNA-binding transcription factor activity
NDY25_RS05885	COG3384	dioxygenase
NDY25_RS05915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDY25_RS05920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDY25_RS05930	COG2096	Adenosyltransferase
NDY25_RS05935	COG0123	including yeast histone deacetylase and acetoin utilization protein
NDY25_RS05950	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NDY25_RS05955	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NDY25_RS05960	COG2967	ApaG domain
NDY25_RS05965	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NDY25_RS05970	COG0431	NADPH-dependent FMN reductase
NDY25_RS05975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDY25_RS05985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NDY25_RS05990	COG1116	anion transmembrane transporter activity
NDY25_RS06010	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NDY25_RS06030	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NDY25_RS06040	COG0642	Histidine kinase
NDY25_RS06055	COG4181	ATPase activity
NDY25_RS06065	COG2175	clavaminate synthase activity
NDY25_RS06075	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NDY25_RS06080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NDY25_RS06100	COG4771	TonB-dependent receptor
NDY25_RS06110	COG0667	Aldo Keto reductase
NDY25_RS06115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NDY25_RS06125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NDY25_RS06130	COG4106	trans-aconitate 2-methyltransferase activity
NDY25_RS06140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NDY25_RS06170	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NDY25_RS06185	COG2357	RelA SpoT domain protein
NDY25_RS06220	COG0604	alcohol dehydrogenase
NDY25_RS06220	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS06220	COG3321	synthase
NDY25_RS06230	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NDY25_RS06245	COG0494	nUDIX hydrolase
NDY25_RS06255	COG0653	protein targeting
NDY25_RS06260	COG0739	heme binding
NDY25_RS06285	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NDY25_RS06290	COG1181	Belongs to the D-alanine--D-alanine ligase family
NDY25_RS06295	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NDY25_RS06315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NDY25_RS06320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NDY25_RS06330	COG3116	cell division
NDY25_RS06375	COG0792	nuclease activity
NDY25_RS06380	COG1988	membrane-bound metal-dependent
NDY25_RS06385	COG0277	FAD linked oxidase domain protein
NDY25_RS06390	COG0823	Involved in the tonB-independent uptake of proteins
NDY25_RS06390	COG4946	Tricorn protease homolog
NDY25_RS06390	COG1506	peptidase
NDY25_RS06395	COG0745	RESPONSE REGULATOR receiver
NDY25_RS06400	COG2205	protein histidine kinase activity
NDY25_RS06410	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NDY25_RS06415	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NDY25_RS06430	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NDY25_RS06465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NDY25_RS06465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NDY25_RS06480	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NDY25_RS06490	COG0488	(ABC) transporter
NDY25_RS06495	COG0242	peptide deformylase activity
NDY25_RS06510	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NDY25_RS06555	COG2188	Transcriptional regulator
NDY25_RS06570	COG1450	Type ii and iii secretion system protein
NDY25_RS06585	COG3166	PFAM Fimbrial assembly family protein
NDY25_RS06590	COG3156	type II secretion system protein K
NDY25_RS06595	COG4795	General secretion pathway protein
NDY25_RS06600	COG2165	general secretion pathway protein
NDY25_RS06605	COG4970	Tfp pilus assembly protein FimT
NDY25_RS06610	COG2165	general secretion pathway protein
NDY25_RS06615	COG1459	type II secretion system
NDY25_RS06620	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NDY25_RS06630	COG5295	Hep Hag repeat protein
NDY25_RS06635	COG1404	Belongs to the peptidase S8 family
NDY25_RS06650	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NDY25_RS06650	COG0047	phosphoribosylformylglycinamidine synthase activity
NDY25_RS06655	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NDY25_RS06660	COG4974	Belongs to the 'phage' integrase family
NDY25_RS06670	COG0795	lipopolysaccharide-transporting ATPase activity
NDY25_RS06690	COG0525	valine-tRNA ligase activity
NDY25_RS06725	COG1183	phosphatidylcholine synthase activity
NDY25_RS06740	COG0442	prolyl-tRNA aminoacylation
NDY25_RS06755	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NDY25_RS06760	COG1127	ABC transporter
NDY25_RS06765	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NDY25_RS06765	COG3218	ABC-type transport auxiliary lipoprotein component
NDY25_RS06795	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NDY25_RS06805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NDY25_RS06810	COG0662	Cupin 2, conserved barrel domain protein
NDY25_RS06810	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NDY25_RS06835	COG2086	electron transfer activity
NDY25_RS06850	COG0463	Glycosyl transferase, family 2
NDY25_RS06870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NDY25_RS06875	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NDY25_RS06945	COG0625	glutathione transferase activity
NDY25_RS06955	COG0513	Belongs to the DEAD box helicase family
NDY25_RS06965	COG4771	TonB-dependent receptor
NDY25_RS06970	COG0720	synthase
NDY25_RS06980	COG1569	PIN domain
NDY25_RS06985	COG3311	Transcriptional regulator
NDY25_RS06990	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NDY25_RS06995	COG1956	GAF domain-containing protein
NDY25_RS07005	COG2819	hydrolase of the alpha beta superfamily
NDY25_RS07015	COG0546	phosphoglycolate phosphatase activity
NDY25_RS07025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NDY25_RS07040	COG0339	signal peptide processing
NDY25_RS07055	COG2132	Multicopper oxidase
NDY25_RS07090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NDY25_RS07100	COG1136	(ABC) transporter
NDY25_RS07110	COG1136	(ABC) transporter
NDY25_RS07110	COG0577	efflux transmembrane transporter activity
NDY25_RS07120	COG4191	Histidine kinase
NDY25_RS07130	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NDY25_RS07145	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NDY25_RS07170	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NDY25_RS07180	COG0356	it plays a direct role in the translocation of protons across the membrane
NDY25_RS07200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NDY25_RS07210	COG0508	dehydrogenase complex catalyzes the overall conversion of
NDY25_RS07245	COG2011	ABC-type metal ion transport system permease component
NDY25_RS07250	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NDY25_RS07255	COG0697	spore germination
NDY25_RS07260	COG1666	GTP binding
NDY25_RS07275	COG1187	pseudouridine synthase activity
NDY25_RS07280	COG2813	Specifically methylates the guanine in position
NDY25_RS07300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NDY25_RS07300	COG0784	Response regulator, receiver
NDY25_RS07300	COG2198	Histidine kinase
NDY25_RS07300	COG2205	protein histidine kinase activity
NDY25_RS07320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NDY25_RS07325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NDY25_RS07380	COG0842	Transport permease protein
NDY25_RS07385	COG1131	(ABC) transporter
NDY25_RS07390	COG0025	NhaP-type Na H and K H
NDY25_RS07400	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NDY25_RS07405	COG1573	uracil-dna glycosylase
NDY25_RS07415	COG3384	dioxygenase
NDY25_RS07425	COG0583	DNA-binding transcription factor activity
NDY25_RS07435	COG0667	Aldo Keto reductase
NDY25_RS07445	COG3590	peptidase
NDY25_RS07460	COG0531	amino acid
NDY25_RS07475	COG2972	Histidine kinase
NDY25_RS07495	COG3685	Protein conserved in bacteria
NDY25_RS07500	COG3546	catalase activity
NDY25_RS07525	COG2204	response regulator
NDY25_RS07540	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS07545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NDY25_RS07565	COG1132	(ABC) transporter
NDY25_RS07575	COG1063	alcohol dehydrogenase
NDY25_RS07600	COG0583	DNA-binding transcription factor activity
NDY25_RS07605	COG2814	Major facilitator Superfamily
NDY25_RS07645	COG1131	(ABC) transporter
NDY25_RS07660	COG0251	oxidation-reduction process
NDY25_RS07680	COG0840	transmembrane signaling receptor activity
NDY25_RS07710	COG0024	Methionine aminopeptidase
NDY25_RS07740	COG1309	transcriptional regulator
NDY25_RS07750	COG1902	pentaerythritol trinitrate reductase activity
NDY25_RS07780	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NDY25_RS07835	COG3039	Transposase
NDY25_RS07855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NDY25_RS07860	COG1490	D-aminoacyl-tRNA deacylase activity
NDY25_RS07865	COG1560	Kdo2-lipid A biosynthetic process
NDY25_RS07875	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NDY25_RS07910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NDY25_RS07910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NDY25_RS07915	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NDY25_RS07920	COG0242	peptide deformylase activity
NDY25_RS07925	COG1652	LysM domain
NDY25_RS07930	COG0758	DNA mediated transformation
NDY25_RS07950	COG1754	DNA topoisomerase type I activity
NDY25_RS07950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NDY25_RS07970	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS07980	COG0616	signal peptide processing
NDY25_RS07985	COG0534	Mate efflux family protein
NDY25_RS08000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NDY25_RS08010	COG0625	glutathione transferase activity
NDY25_RS08025	COG1252	NADH dehydrogenase
NDY25_RS08030	COG2860	membrane
NDY25_RS08035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NDY25_RS08040	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NDY25_RS08045	COG2201	protein-glutamate methylesterase activity
NDY25_RS08050	COG2177	Part of the ABC transporter FtsEX involved in
NDY25_RS08055	COG2884	Cell division ATP-binding protein ftsE
NDY25_RS08065	COG3118	belongs to the thioredoxin family
NDY25_RS08070	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NDY25_RS08105	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NDY25_RS08135	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NDY25_RS08135	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NDY25_RS08140	COG1473	amidohydrolase
NDY25_RS08145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDY25_RS08150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NDY25_RS08160	COG5383	Protein conserved in bacteria
NDY25_RS08200	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NDY25_RS08220	COG3023	N-Acetylmuramoyl-L-alanine amidase
NDY25_RS08230	COG4948	Mandelate Racemase Muconate Lactonizing
NDY25_RS08240	COG0531	amino acid
NDY25_RS08255	COG4682	membrane
NDY25_RS08260	COG2133	pyrroloquinoline quinone binding
NDY25_RS08275	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NDY25_RS08290	COG1610	YqeY-like protein
NDY25_RS08295	COG1295	ribonuclease BN
NDY25_RS08315	COG0109	protoheme IX farnesyltransferase activity
NDY25_RS08345	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NDY25_RS08360	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NDY25_RS08405	COG0739	heme binding
NDY25_RS08420	COG2807	transmembrane transport
NDY25_RS08425	COG0708	Exodeoxyribonuclease III
NDY25_RS08440	COG1192	Involved in chromosome partitioning
NDY25_RS08445	COG1475	DNA binding
NDY25_RS08460	COG0463	Glycosyl transferase, family 2
NDY25_RS08480	COG0756	dUTP diphosphatase activity
NDY25_RS08485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NDY25_RS08495	COG0018	arginyl-trna synthetase
NDY25_RS08505	COG4221	oxidoreductase activity
NDY25_RS08530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDY25_RS08535	COG1166	arginine decarboxylase activity
NDY25_RS08540	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NDY25_RS08575	COG0606	chelatase, subunit chli
NDY25_RS08590	COG4943	cyclic-guanylate-specific phosphodiesterase activity
NDY25_RS08640	COG1090	epimerase
NDY25_RS08670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NDY25_RS08695	COG1011	Hydrolase
NDY25_RS08700	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NDY25_RS08730	COG2197	response regulator
NDY25_RS08735	COG4585	Histidine kinase
NDY25_RS08740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDY25_RS08745	COG1136	(ABC) transporter
NDY25_RS08750	COG3039	Transposase
NDY25_RS08775	COG0697	spore germination
NDY25_RS08800	COG0180	Tryptophanyl-tRNA synthetase
NDY25_RS08805	COG3237	CsbD-like
NDY25_RS08845	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NDY25_RS08860	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NDY25_RS08865	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NDY25_RS08865	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NDY25_RS08875	COG3228	Belongs to the MtfA family
NDY25_RS08905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NDY25_RS08925	COG1199	ATP-dependent helicase activity
NDY25_RS08950	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NDY25_RS09005	COG2801	Transposase and inactivated derivatives
NDY25_RS09055	COG0625	glutathione transferase activity
NDY25_RS09090	COG4555	ABC transporter
NDY25_RS09100	COG1476	TRANSCRIPTIONal
NDY25_RS09125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NDY25_RS09130	COG1131	(ABC) transporter
NDY25_RS09135	COG0842	Transport permease protein
NDY25_RS09155	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NDY25_RS09180	COG1607	acyl-coa hydrolase
NDY25_RS09185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDY25_RS09205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NDY25_RS09210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NDY25_RS09220	COG0045	succinate-CoA ligase (ADP-forming) activity
NDY25_RS09220	COG1042	CoA-binding domain protein
NDY25_RS09220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NDY25_RS09235	COG1629	transport
NDY25_RS09235	COG4771	TonB-dependent receptor
NDY25_RS09240	COG2239	Acts as a magnesium transporter
NDY25_RS09250	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NDY25_RS09255	COG3387	PFAM Glycoside hydrolase 15-related
NDY25_RS09265	COG3100	YcgL domain-containing protein
NDY25_RS09270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NDY25_RS09290	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS09335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NDY25_RS09415	COG3621	Patatin-like phospholipase
NDY25_RS09435	COG0210	DNA helicase
NDY25_RS09445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDY25_RS09455	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NDY25_RS09465	COG2159	amidohydrolase
NDY25_RS09490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDY25_RS09515	COG3540	Alkaline phosphatase
NDY25_RS09525	COG2091	lysine biosynthetic process via aminoadipic acid
NDY25_RS09540	COG0708	Exodeoxyribonuclease III
NDY25_RS09565	COG1940	carbohydrate kinase activity
NDY25_RS09590	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NDY25_RS09595	COG3162	membrane
NDY25_RS09645	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS09650	COG0179	Fumarylacetoacetate (FAA) hydrolase
NDY25_RS09655	COG4948	Mandelate Racemase Muconate Lactonizing
NDY25_RS09660	COG3254	rhamnose metabolic process
NDY25_RS09665	COG0738	Major facilitator superfamily
NDY25_RS09670	COG1414	Transcriptional regulator
NDY25_RS09685	COG1971	Probably functions as a manganese efflux pump
NDY25_RS09690	COG2205	protein histidine kinase activity
NDY25_RS09695	COG3459	Glycosyltransferase 36 associated
NDY25_RS09700	COG2211	Major facilitator Superfamily
NDY25_RS09705	COG3265	gluconokinase activity
NDY25_RS09710	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NDY25_RS09735	COG2911	Protein conserved in bacteria
NDY25_RS09740	COG0729	surface antigen
NDY25_RS09745	COG4771	TonB-dependent receptor
NDY25_RS09750	COG0457	Tetratricopeptide repeat
NDY25_RS09765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NDY25_RS09780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NDY25_RS09780	COG0519	Catalyzes the synthesis of GMP from XMP
NDY25_RS09790	COG0805	protein transport
NDY25_RS09795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NDY25_RS09800	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NDY25_RS09810	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NDY25_RS09825	COG2974	May be involved in recombination
NDY25_RS09830	COG0037	tRNA processing
NDY25_RS09835	COG2115	Belongs to the xylose isomerase family
NDY25_RS09845	COG3661	Belongs to the glycosyl hydrolase 67 family
NDY25_RS09855	COG4948	Mandelate Racemase Muconate Lactonizing
NDY25_RS09865	COG1472	Belongs to the glycosyl hydrolase 3 family
NDY25_RS09870	COG0246	Mannitol dehydrogenase
NDY25_RS09900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NDY25_RS09905	COG1620	l-lactate permease
NDY25_RS09920	COG3386	PFAM SMP-30 Gluconolaconase
NDY25_RS09930	COG3250	beta-galactosidase activity
NDY25_RS09935	COG1904	glucuronate isomerase
NDY25_RS09940	COG3693	PFAM glycoside hydrolase, family 10
NDY25_RS09955	COG2211	Major facilitator Superfamily
NDY25_RS09990	COG2937	Belongs to the GPAT DAPAT family
NDY25_RS10020	COG0284	orotidine-5'-phosphate decarboxylase activity
NDY25_RS10025	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NDY25_RS10030	COG3132	Protein of unknown function, DUF480
NDY25_RS10050	COG0210	DNA helicase
NDY25_RS10055	COG1435	thymidine kinase activity
NDY25_RS10065	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NDY25_RS10075	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NDY25_RS10105	COG3135	benzoate transporter
NDY25_RS10125	COG0676	glucose-6-phosphate 1-epimerase activity
NDY25_RS10140	COG0730	response to heat
NDY25_RS10175	COG0302	gtp cyclohydrolase
NDY25_RS10190	COG1566	PFAM secretion protein HlyD family protein
NDY25_RS10200	COG1289	transmembrane transporter activity
NDY25_RS10205	COG0477	Major facilitator Superfamily
NDY25_RS10215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDY25_RS10290	COG2801	Transposase and inactivated derivatives
NDY25_RS10330	COG2207	Transcriptional regulator
NDY25_RS10335	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS10345	COG3549	Plasmid maintenance system killer
NDY25_RS10360	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NDY25_RS10365	COG1074	ATP-dependent DNA helicase activity
NDY25_RS10370	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NDY25_RS10405	COG1127	ABC transporter
NDY25_RS10410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NDY25_RS10415	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NDY25_RS10430	COG2853	Lipoprotein
NDY25_RS10450	COG0386	Belongs to the glutathione peroxidase family
NDY25_RS10460	COG1322	Protein conserved in bacteria
NDY25_RS10465	COG0625	glutathione transferase activity
NDY25_RS10470	COG0531	amino acid
NDY25_RS10475	COG3537	Alpha-1,2-mannosidase
NDY25_RS10495	COG2203	Gaf domain
NDY25_RS10495	COG2199	diguanylate cyclase activity
NDY25_RS10500	COG3835	regulator
NDY25_RS10505	COG1929	Belongs to the glycerate kinase type-1 family
NDY25_RS10510	COG2271	Major facilitator Superfamily
NDY25_RS10560	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NDY25_RS10565	COG0861	Integral membrane protein TerC family
NDY25_RS10575	COG0584	glycerophosphoryl diester phosphodiesterase
NDY25_RS10590	COG0671	phosphoesterase, PA-phosphatase related
NDY25_RS10600	COG3293	Transposase
NDY25_RS10615	COG0706	membrane insertase activity
NDY25_RS10645	COG0187	DNA topoisomerase II activity
NDY25_RS10655	COG0501	Belongs to the peptidase M48B family
NDY25_RS10690	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NDY25_RS10700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDY25_RS10735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NDY25_RS10740	COG0793	Belongs to the peptidase S41A family
NDY25_RS10745	COG4942	peptidase
NDY25_RS10755	COG2234	aminopeptidase activity
NDY25_RS10770	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NDY25_RS10775	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NDY25_RS10780	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NDY25_RS10785	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NDY25_RS10790	COG1064	alcohol dehydrogenase
NDY25_RS10800	COG0493	'glutamate synthase
NDY25_RS10805	COG0067	glutamate synthase
NDY25_RS10805	COG0069	glutamate synthase activity
NDY25_RS10805	COG0070	glutamate synthase
NDY25_RS10840	COG1741	Belongs to the pirin family
NDY25_RS10850	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NDY25_RS10865	COG3459	Glycosyltransferase 36 associated
NDY25_RS10870	COG3459	Glycosyltransferase 36 associated
NDY25_RS10880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NDY25_RS10930	COG1111	helicase
NDY25_RS10930	COG1205	dead DEAH box helicase
NDY25_RS10935	COG3177	Filamentation induced by cAMP protein fic
NDY25_RS10940	COG1272	protein, Hemolysin III
NDY25_RS10970	COG0583	DNA-binding transcription factor activity
NDY25_RS10975	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS10985	COG1733	regulation of RNA biosynthetic process
NDY25_RS11100	COG1484	DNA-dependent DNA replication
NDY25_RS11105	COG4584	PFAM Integrase catalytic
NDY25_RS11135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NDY25_RS11145	COG3237	CsbD-like
NDY25_RS11185	COG0657	acetylesterase activity
NDY25_RS11195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDY25_RS11240	COG0714	Associated with various cellular activities
NDY25_RS11300	COG4772	TonB-dependent receptor
NDY25_RS11310	COG0662	Cupin 2, conserved barrel domain protein
NDY25_RS11320	COG1012	belongs to the aldehyde dehydrogenase family
NDY25_RS11385	COG1755	Isoprenylcysteine carboxyl methyltransferase
NDY25_RS11390	COG4585	Histidine kinase
NDY25_RS11395	COG2197	response regulator
NDY25_RS11410	COG3710	Transcriptional regulator
NDY25_RS11430	COG4771	TonB-dependent receptor
NDY25_RS11630	COG0366	Alpha amylase catalytic
NDY25_RS11635	COG0366	Alpha amylase catalytic
NDY25_RS11640	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NDY25_RS11670	COG2755	lipolytic protein G-D-S-L family
NDY25_RS11680	COG0657	acetylesterase activity
NDY25_RS11680	COG2755	lipolytic protein G-D-S-L family
NDY25_RS11690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NDY25_RS11705	COG3507	Belongs to the glycosyl hydrolase 43 family
NDY25_RS11710	COG1609	Transcriptional regulator
NDY25_RS11715	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NDY25_RS11720	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS11730	COG2755	lipolytic protein G-D-S-L family
NDY25_RS11755	COG3186	Phenylalanine-4-hydroxylase
NDY25_RS11760	COG1522	sequence-specific DNA binding
NDY25_RS11770	COG1752	Esterase of the alpha-beta hydrolase superfamily
NDY25_RS11775	COG1119	ATPase activity
NDY25_RS11790	COG0517	IMP dehydrogenase activity
NDY25_RS11790	COG1125	glycine betaine transport
NDY25_RS11805	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NDY25_RS11815	COG3550	peptidyl-serine autophosphorylation
NDY25_RS11820	COG1396	sequence-specific DNA binding
NDY25_RS11840	COG0489	protein tyrosine kinase activity
NDY25_RS11845	COG2062	phosphohistidine phosphatase, SixA
NDY25_RS11855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDY25_RS11875	COG3039	Transposase
NDY25_RS11885	COG1881	PFAM PEBP family protein
NDY25_RS11900	COG0174	glutamine synthetase
NDY25_RS11905	COG0347	Belongs to the P(II) protein family
NDY25_RS11910	COG0004	ammonium transporteR
NDY25_RS11915	COG3852	Histidine kinase
NDY25_RS11920	COG2204	response regulator
NDY25_RS11925	COG2032	superoxide dismutase activity
NDY25_RS11930	COG2032	superoxide dismutase activity
NDY25_RS11940	COG0183	Belongs to the thiolase family
NDY25_RS11980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NDY25_RS11990	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NDY25_RS12000	COG0028	Belongs to the TPP enzyme family
NDY25_RS12030	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NDY25_RS12045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NDY25_RS12050	COG3177	Filamentation induced by cAMP protein fic
NDY25_RS12055	COG0596	Alpha beta hydrolase
NDY25_RS12060	COG0727	PFAM Uncharacterised protein family (UPF0153)
NDY25_RS12065	COG0318	PFAM AMP-dependent synthetase and ligase
NDY25_RS12080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NDY25_RS12095	COG1181	Belongs to the D-alanine--D-alanine ligase family
NDY25_RS12110	COG0564	pseudouridine synthase activity
NDY25_RS12130	COG1446	asparaginase
NDY25_RS12165	COG0475	glutathione-regulated potassium exporter activity
NDY25_RS12170	COG0583	DNA-binding transcription factor activity
NDY25_RS12175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NDY25_RS12180	COG2224	Isocitrate lyase
NDY25_RS12215	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NDY25_RS12220	COG1960	acyl-CoA dehydrogenase activity
NDY25_RS12275	COG0523	cobalamin synthesis protein
NDY25_RS12290	COG0697	spore germination
NDY25_RS12300	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NDY25_RS12315	COG1846	Transcriptional regulator
NDY25_RS12320	COG1764	response to oxidative stress
NDY25_RS12345	COG0656	L-ascorbic acid biosynthetic process
NDY25_RS12350	COG2130	NADP-dependent
NDY25_RS12365	COG1187	pseudouridine synthase activity
NDY25_RS12375	COG1643	Atp-dependent helicase
NDY25_RS12380	COG0840	transmembrane signaling receptor activity
NDY25_RS12385	COG4807	Protein conserved in bacteria
NDY25_RS12390	COG2351	hydroxyisourate hydrolase activity
NDY25_RS12395	COG2072	flavoprotein involved in K transport
NDY25_RS12415	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NDY25_RS12470	COG3039	Transposase
NDY25_RS12475	COG3039	Transposase
NDY25_RS12515	COG2252	PERMEase
NDY25_RS12535	COG0084	hydrolase, TatD family'
NDY25_RS12545	COG0583	DNA-binding transcription factor activity
NDY25_RS12550	COG2814	Major facilitator Superfamily
NDY25_RS12560	COG0596	Alpha beta hydrolase
NDY25_RS12580	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NDY25_RS12585	COG1902	pentaerythritol trinitrate reductase activity
NDY25_RS12605	COG2223	nitrite transmembrane transporter activity
NDY25_RS12610	COG0745	RESPONSE REGULATOR receiver
NDY25_RS12615	COG2205	protein histidine kinase activity
NDY25_RS12620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDY25_RS12640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NDY25_RS12645	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NDY25_RS12675	COG0702	epimerase
NDY25_RS12680	COG1733	regulation of RNA biosynthetic process
NDY25_RS12775	COG3039	Transposase
NDY25_RS12810	COG0129	dihydroxy-acid dehydratase activity
NDY25_RS12820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NDY25_RS12870	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NDY25_RS12875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NDY25_RS12910	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NDY25_RS12915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NDY25_RS12925	COG3485	protocatechuate 3,4-dioxygenase
NDY25_RS12930	COG3485	protocatechuate 3,4-dioxygenase
NDY25_RS12940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NDY25_RS12945	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NDY25_RS12955	COG1414	Transcriptional regulator
NDY25_RS12965	COG0657	acetylesterase activity
NDY25_RS12975	COG0445	tRNA wobble uridine modification
NDY25_RS12985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NDY25_RS13025	COG0156	8-amino-7-oxononanoate synthase activity
NDY25_RS13030	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NDY25_RS13035	COG1040	competence protein
NDY25_RS13065	COG1511	domain protein
NDY25_RS13065	COG3264	Mechanosensitive ion channel
NDY25_RS13075	COG1368	sulfuric ester hydrolase activity
NDY25_RS13080	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NDY25_RS13085	COG2354	Protein conserved in bacteria
NDY25_RS13090	COG1649	PFAM Uncharacterised BCR, COG1649
NDY25_RS13100	COG0297	glycogen (starch) synthase activity
NDY25_RS13105	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NDY25_RS13110	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NDY25_RS13135	COG0702	epimerase
NDY25_RS13150	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS13185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NDY25_RS13195	COG0513	Belongs to the DEAD box helicase family
NDY25_RS13205	COG0508	dehydrogenase complex catalyzes the overall conversion of
NDY25_RS13220	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NDY25_RS13235	COG3104	oligopeptide transport
NDY25_RS13255	COG2852	Protein conserved in bacteria
NDY25_RS13265	COG3039	Transposase
NDY25_RS13300	COG1320	monovalent cation:proton antiporter activity
NDY25_RS13305	COG2212	antiporter activity
NDY25_RS13315	COG0651	ATP synthesis coupled electron transport
NDY25_RS13320	COG1006	Multisubunit Na H antiporter MnhC subunit
NDY25_RS13380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NDY25_RS13390	COG1597	lipid kinase activity
NDY25_RS13415	COG2963	transposase activity
NDY25_RS13450	COG3039	Transposase
NDY25_RS13460	COG3039	Transposase
NDY25_RS13470	COG3039	Transposase
NDY25_RS13555	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NDY25_RS13625	COG0840	transmembrane signaling receptor activity
NDY25_RS13640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NDY25_RS13645	COG0134	indole-3-glycerol-phosphate synthase activity
NDY25_RS13655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NDY25_RS13670	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
NDY25_RS13735	COG0316	Belongs to the HesB IscA family
NDY25_RS13740	COG2816	NAD+ diphosphatase activity
NDY25_RS13745	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NDY25_RS13765	COG2814	Major facilitator Superfamily
NDY25_RS13770	COG1289	transmembrane transporter activity
NDY25_RS13775	COG0151	Belongs to the GarS family
NDY25_RS13780	COG0138	bifunctional purine biosynthesis protein purh
NDY25_RS13810	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NDY25_RS13830	COG2264	protein methyltransferase activity
NDY25_RS13845	COG0439	Biotin carboxylase
NDY25_RS13855	COG0511	ligase activity, forming carbon-carbon bonds
NDY25_RS13860	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NDY25_RS13880	COG1324	tolerance protein
NDY25_RS13885	COG2356	endonuclease I
NDY25_RS13900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDY25_RS13915	COG2189	Belongs to the N(4) N(6)-methyltransferase family
NDY25_RS13950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NDY25_RS13975	COG3712	iron ion homeostasis
NDY25_RS14000	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NDY25_RS14015	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NDY25_RS14040	COG2353	YceI-like domain
NDY25_RS14065	COG3052	prosthetic group binding
NDY25_RS14100	COG1802	Transcriptional regulator
NDY25_RS14115	COG1366	Belongs to the anti-sigma-factor antagonist family
NDY25_RS14175	COG2801	Transposase and inactivated derivatives
NDY25_RS14255	COG3039	Transposase
NDY25_RS14265	COG3039	Transposase
NDY25_RS14285	COG4206	TonB-dependent receptor
NDY25_RS14290	COG0823	Involved in the tonB-independent uptake of proteins
NDY25_RS14290	COG1506	peptidase
NDY25_RS14335	COG0435	Glutathione S-transferase
NDY25_RS14370	COG0823	Involved in the tonB-independent uptake of proteins
NDY25_RS14370	COG1506	peptidase
NDY25_RS14405	COG0697	spore germination
NDY25_RS14420	COG4305	rare lipoprotein A
NDY25_RS14425	COG1113	amino acid transport
NDY25_RS14440	COG3507	Belongs to the glycosyl hydrolase 43 family
NDY25_RS14485	COG0840	transmembrane signaling receptor activity
NDY25_RS14495	COG0659	secondary active sulfate transmembrane transporter activity
NDY25_RS14525	COG3275	phosphorelay sensor kinase activity
NDY25_RS14535	COG0181	hydroxymethylbilane synthase activity
NDY25_RS14560	COG1505	serine-type exopeptidase activity
NDY25_RS14565	COG0436	Aminotransferase
NDY25_RS14575	COG2832	Protein of unknown function (DUF454)
NDY25_RS14585	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NDY25_RS14595	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NDY25_RS14600	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NDY25_RS14605	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NDY25_RS14610	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NDY25_RS14635	COG2226	methyltransferase
NDY25_RS14640	COG5001	Diguanylate cyclase
NDY25_RS14640	COG3300	MHYT domain
NDY25_RS14645	COG0308	aminopeptidase N
NDY25_RS14680	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NDY25_RS14700	COG0730	response to heat
NDY25_RS14705	COG1012	belongs to the aldehyde dehydrogenase family
NDY25_RS14710	COG0367	asparagine synthase
NDY25_RS14715	COG1213	nucleotidyl transferase
NDY25_RS14725	COG0028	Belongs to the TPP enzyme family
NDY25_RS14725	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
NDY25_RS14740	COG3284	Transcriptional regulator
NDY25_RS14745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NDY25_RS14750	COG1077	Cell shape determining protein MreB Mrl
NDY25_RS14755	COG1792	Involved in formation and maintenance of cell shape
NDY25_RS14760	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NDY25_RS14770	COG0772	Belongs to the SEDS family
NDY25_RS14795	COG2951	lytic endotransglycosylase activity
NDY25_RS14800	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NDY25_RS14805	COG1686	Belongs to the peptidase S11 family
NDY25_RS14825	COG0321	lipoyl(octanoyl) transferase activity
NDY25_RS14830	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NDY25_RS14845	COG1051	belongs to the nudix hydrolase family
NDY25_RS14845	COG1056	cytidyltransferase-related domain
NDY25_RS14880	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NDY25_RS14885	COG0673	inositol 2-dehydrogenase activity
NDY25_RS14890	COG2823	Periplasmic or secreted lipoprotein
NDY25_RS14915	COG4251	negative regulation of phosphorylation
NDY25_RS14920	COG0784	Response regulator, receiver
NDY25_RS14925	COG4191	Histidine kinase
NDY25_RS14930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NDY25_RS14935	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS14980	COG1459	type II secretion system
NDY25_RS15005	COG3156	type II secretion system protein K
NDY25_RS15030	COG3250	beta-galactosidase activity
NDY25_RS15045	COG2188	Transcriptional regulator
NDY25_RS15055	COG1609	Transcriptional regulator
NDY25_RS15060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NDY25_RS15065	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NDY25_RS15105	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NDY25_RS15115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NDY25_RS15125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NDY25_RS15140	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NDY25_RS15145	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NDY25_RS15160	COG2205	protein histidine kinase activity
NDY25_RS15180	COG3920	Histidine kinase
NDY25_RS15195	COG3791	Glutathione-dependent formaldehyde-activating
NDY25_RS15205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NDY25_RS15215	COG0697	spore germination
NDY25_RS15255	COG0402	S-adenosylhomocysteine deaminase activity
NDY25_RS15270	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NDY25_RS15275	COG0726	polysaccharide deacetylase
NDY25_RS15280	COG4773	Receptor
NDY25_RS15300	COG0436	Aminotransferase
NDY25_RS15340	COG2211	Major facilitator Superfamily
NDY25_RS15345	COG1609	Transcriptional regulator
NDY25_RS15350	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS15355	COG2851	Citrate transporter
NDY25_RS15370	COG0642	Histidine kinase
NDY25_RS15380	COG2197	response regulator
NDY25_RS15390	COG0583	DNA-binding transcription factor activity
NDY25_RS15410	COG4191	Histidine kinase
NDY25_RS15425	COG0280	phosphate acetyltransferase
NDY25_RS15425	COG0281	malic enzyme
NDY25_RS15450	COG1560	Kdo2-lipid A biosynthetic process
NDY25_RS15455	COG1519	Transferase
NDY25_RS15460	COG1538	Outer membrane efflux protein
NDY25_RS15465	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NDY25_RS15485	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NDY25_RS15490	COG0066	3-isopropylmalate dehydratase activity
NDY25_RS15495	COG2226	methyltransferase
NDY25_RS15500	COG0473	3-isopropylmalate dehydrogenase activity
NDY25_RS15505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NDY25_RS15525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NDY25_RS15530	COG0405	Gamma-glutamyltransferase
NDY25_RS15535	COG0840	transmembrane signaling receptor activity
NDY25_RS15545	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NDY25_RS15550	COG3710	Transcriptional regulator
NDY25_RS15570	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NDY25_RS15580	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NDY25_RS15595	COG0563	adenylate kinase activity
NDY25_RS15600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NDY25_RS15610	COG3781	membrane
NDY25_RS15615	COG0671	phosphoesterase, PA-phosphatase related
NDY25_RS15630	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS15645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NDY25_RS15650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NDY25_RS15680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NDY25_RS15685	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
NDY25_RS15695	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NDY25_RS15705	COG0352	thiamine-phosphate diphosphorylase activity
NDY25_RS15710	COG1773	rubredoxin
NDY25_RS15715	COG2912	Transglutaminase-like superfamily
NDY25_RS15735	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NDY25_RS15760	COG0006	proline dipeptidase activity
NDY25_RS15770	COG0006	proline dipeptidase activity
NDY25_RS15785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NDY25_RS15790	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NDY25_RS15795	COG0346	lactoylglutathione lyase activity
NDY25_RS15800	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NDY25_RS15805	COG1561	YicC-like family, N-terminal region
NDY25_RS15820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NDY25_RS15830	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NDY25_RS15855	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NDY25_RS15885	COG0714	Associated with various cellular activities
NDY25_RS15915	COG1301	dicarboxylic acid transport
NDY25_RS15930	COG4773	Receptor
NDY25_RS15935	COG0583	DNA-binding transcription factor activity
NDY25_RS15940	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS15950	COG1376	ErfK ybiS ycfS ynhG family protein
NDY25_RS15985	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NDY25_RS15990	COG4149	molybdate abc transporter
NDY25_RS15995	COG0725	ABC transporter, periplasmic molybdate-binding protein
NDY25_RS16000	COG3453	Protein conserved in bacteria
NDY25_RS16000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDY25_RS16010	COG3047	cAMP biosynthetic process
NDY25_RS16025	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NDY25_RS16055	COG0469	pyruvate kinase activity
NDY25_RS16060	COG3588	fructose-bisphosphate aldolase
NDY25_RS16065	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NDY25_RS16080	COG1648	precorrin-2 dehydrogenase activity
NDY25_RS16080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NDY25_RS16095	COG0784	Response regulator, receiver
NDY25_RS16095	COG2198	Histidine kinase
NDY25_RS16095	COG2205	protein histidine kinase activity
NDY25_RS16115	COG0175	sulfate reduction
NDY25_RS16120	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NDY25_RS16125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NDY25_RS16135	COG2895	sulfate adenylyltransferase (ATP) activity
NDY25_RS16135	COG0529	Catalyzes the synthesis of activated sulfate
NDY25_RS16140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDY25_RS16145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NDY25_RS16170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NDY25_RS16195	COG3039	Transposase
NDY25_RS16225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NDY25_RS16230	COG2272	Belongs to the type-B carboxylesterase lipase family
NDY25_RS16245	COG4948	Mandelate Racemase Muconate Lactonizing
NDY25_RS16250	COG3250	beta-galactosidase activity
NDY25_RS16260	COG1609	Transcriptional regulator
NDY25_RS16290	COG0471	metal ion transport
NDY25_RS16290	COG3273	potassium ion transport
NDY25_RS16295	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NDY25_RS16345	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NDY25_RS16380	COG2801	Transposase and inactivated derivatives
NDY25_RS16385	COG3220	belongs to the UPF0276 family
NDY25_RS16440	COG3039	Transposase
NDY25_RS16575	COG2814	Major facilitator Superfamily
NDY25_RS16595	COG3039	Transposase
NDY25_RS16635	COG2856	Zn peptidase
NDY25_RS16650	COG0583	DNA-binding transcription factor activity
NDY25_RS16655	COG1238	metal cluster binding
NDY25_RS16660	COG0840	transmembrane signaling receptor activity
NDY25_RS16695	COG0189	ligase activity
NDY25_RS16700	COG0745	RESPONSE REGULATOR receiver
NDY25_RS16730	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NDY25_RS16740	COG4969	Belongs to the N-Me-Phe pilin family
NDY25_RS16750	COG2194	sulfuric ester hydrolase activity
NDY25_RS16795	COG0045	succinate-CoA ligase (ADP-forming) activity
NDY25_RS16800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NDY25_RS16830	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NDY25_RS16830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NDY25_RS16840	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NDY25_RS16845	COG0564	pseudouridine synthase activity
NDY25_RS16860	COG3011	Protein conserved in bacteria
NDY25_RS16865	COG0840	transmembrane signaling receptor activity
NDY25_RS16880	COG3387	PFAM Glycoside hydrolase 15-related
NDY25_RS16885	COG1877	trehalose-phosphatase activity
NDY25_RS16930	COG4771	TonB-dependent receptor
NDY25_RS16940	COG0667	Aldo Keto reductase
NDY25_RS16945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NDY25_RS16950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NDY25_RS16955	COG1116	anion transmembrane transporter activity
NDY25_RS16960	COG0542	response to heat
NDY25_RS16970	COG4206	TonB-dependent receptor
NDY25_RS16975	COG1492	cobalamin metabolic process
NDY25_RS16985	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NDY25_RS17000	COG5297	Belongs to the glycosyl hydrolase family 6
NDY25_RS17005	COG5599	Phosphatase
NDY25_RS17015	COG0019	diaminopimelate decarboxylase activity
NDY25_RS17020	COG4264	IucA IucC family
NDY25_RS17025	COG2814	Major facilitator Superfamily
NDY25_RS17030	COG4264	IucA IucC family
NDY25_RS17040	COG4772	TonB-dependent receptor
NDY25_RS17050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NDY25_RS17050	COG4651	solute:proton antiporter activity
NDY25_RS17075	COG0488	(ABC) transporter
NDY25_RS17090	COG0477	Major facilitator Superfamily
NDY25_RS17145	COG2255	four-way junction helicase activity
NDY25_RS17150	COG0824	Thioesterase
NDY25_RS17160	COG0848	biopolymer transport protein
NDY25_RS17175	COG2885	chlorophyll binding
NDY25_RS17185	COG0602	queuosine metabolic process
NDY25_RS17190	COG0667	Aldo Keto reductase
NDY25_RS17200	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NDY25_RS17205	COG3920	Histidine kinase
NDY25_RS17225	COG0840	transmembrane signaling receptor activity
NDY25_RS17235	COG1187	pseudouridine synthase activity
NDY25_RS17250	COG0514	ATP-dependent DNA helicase (RecQ)
NDY25_RS17255	COG0783	Belongs to the Dps family
NDY25_RS17260	COG1643	Atp-dependent helicase
NDY25_RS17270	COG0837	glucose binding
NDY25_RS17280	COG0535	radical SAM domain protein
NDY25_RS17295	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NDY25_RS17305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NDY25_RS17315	COG1216	Glycosyl transferase, family 2
NDY25_RS17320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NDY25_RS17330	COG1199	ATP-dependent helicase activity
NDY25_RS17345	COG0189	ligase activity
NDY25_RS17360	COG0835	chemotaxis
NDY25_RS17365	COG0840	transmembrane signaling receptor activity
NDY25_RS17370	COG0643	Histidine kinase
NDY25_RS17370	COG0784	Response regulator, receiver
NDY25_RS17370	COG2198	Histidine kinase
NDY25_RS17375	COG2201	protein-glutamate methylesterase activity
NDY25_RS17405	COG1595	DNA-templated transcription, initiation
NDY25_RS17415	COG1446	asparaginase
NDY25_RS17445	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NDY25_RS17450	COG0732	type I restriction modification DNA specificity domain
NDY25_RS17465	COG3645	SOS response
NDY25_RS17510	COG3537	Alpha-1,2-mannosidase
NDY25_RS17520	COG1486	melibiose metabolic process
NDY25_RS17535	COG0531	amino acid
NDY25_RS17565	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NDY25_RS17570	COG1388	LysM domain
NDY25_RS17570	COG3858	chitin binding
NDY25_RS17585	COG0837	glucose binding
NDY25_RS17590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NDY25_RS17600	COG0494	nUDIX hydrolase
NDY25_RS17605	COG1218	3'(2'),5'-bisphosphate nucleotidase
NDY25_RS17610	COG3956	TIGRFAM MazG family protein
NDY25_RS17615	COG1742	UPF0060 membrane protein
NDY25_RS17620	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NDY25_RS17625	COG0509	glycine decarboxylation via glycine cleavage system
NDY25_RS17650	COG1960	acyl-CoA dehydrogenase activity
NDY25_RS17660	COG1309	transcriptional regulator
NDY25_RS17675	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NDY25_RS17685	COG0463	Glycosyl transferase, family 2
NDY25_RS17690	COG0517	IMP dehydrogenase activity
NDY25_RS17690	COG0516	GMP reductase activity
NDY25_RS17700	COG2982	Protein involved in outer membrane biogenesis
NDY25_RS17705	COG1272	protein, Hemolysin III
NDY25_RS17710	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NDY25_RS17720	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NDY25_RS17725	COG0626	cystathionine gamma-synthase activity
NDY25_RS17730	COG0527	aspartate kinase activity
NDY25_RS17730	COG0460	homoserine dehydrogenase
NDY25_RS17740	COG1760	l-serine dehydratase
NDY25_RS17750	COG1278	Cold shock
NDY25_RS17760	COG3038	cytochrome b561
NDY25_RS17765	COG2353	YceI-like domain
NDY25_RS17770	COG2205	protein histidine kinase activity
NDY25_RS17770	COG2198	Histidine kinase
NDY25_RS17770	COG0784	Response regulator, receiver
NDY25_RS17785	COG0477	Major facilitator Superfamily
NDY25_RS17790	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NDY25_RS17800	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NDY25_RS17805	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NDY25_RS17810	COG0259	pyridoxamine-phosphate oxidase activity
NDY25_RS17825	COG1842	Phage shock protein A
NDY25_RS17850	COG0754	glutathionylspermidine amidase activity
NDY25_RS17860	COG0789	Transcriptional regulator
NDY25_RS17910	COG0531	amino acid
NDY25_RS17915	COG2197	response regulator
NDY25_RS17930	COG1113	amino acid transport
NDY25_RS17940	COG1271	oxidase subunit
NDY25_RS17945	COG1294	oxidase, subunit
NDY25_RS17955	COG2239	Acts as a magnesium transporter
NDY25_RS17960	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NDY25_RS17965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NDY25_RS17985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NDY25_RS18000	COG1137	ATPase activity
NDY25_RS18005	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NDY25_RS18015	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NDY25_RS18030	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NDY25_RS18050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NDY25_RS18070	COG0628	permease
NDY25_RS18110	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NDY25_RS18115	COG0084	hydrolase, TatD family'
NDY25_RS18130	COG1960	acyl-CoA dehydrogenase activity
NDY25_RS18145	COG0367	asparagine synthase
NDY25_RS18155	COG0305	Participates in initiation and elongation during chromosome replication
NDY25_RS18160	COG0415	Belongs to the DNA photolyase family
NDY25_RS18170	COG0583	DNA-binding transcription factor activity
NDY25_RS18185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDY25_RS18215	COG3706	GGDEF domain
NDY25_RS18290	COG3039	Transposase
NDY25_RS18320	COG0556	nucleotide-excision repair
NDY25_RS18335	COG3505	Type IV secretory pathway VirD4
NDY25_RS18355	COG2948	multi-organism process
NDY25_RS18375	COG3702	type iv secretory pathway
NDY25_RS18390	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NDY25_RS18395	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NDY25_RS18410	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NDY25_RS18415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDY25_RS18415	COG0072	phenylalanine-tRNA ligase activity
NDY25_RS18465	COG0438	transferase activity, transferring glycosyl groups
NDY25_RS18470	COG0438	transferase activity, transferring glycosyl groups
NDY25_RS18480	COG0438	transferase activity, transferring glycosyl groups
NDY25_RS18505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NDY25_RS18510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDY25_RS18515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NDY25_RS18535	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NDY25_RS18545	COG1960	acyl-CoA dehydrogenase activity
NDY25_RS18555	COG3040	lipid binding
NDY25_RS18575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NDY25_RS18585	COG4191	Histidine kinase
NDY25_RS18585	COG0784	Response regulator, receiver
NDY25_RS18595	COG1194	a g-specific adenine glycosylase
NDY25_RS18610	COG3938	Belongs to the proline racemase family
NDY25_RS18615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NDY25_RS18630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NDY25_RS18640	COG0006	proline dipeptidase activity
NDY25_RS18655	COG0531	amino acid
NDY25_RS18730	COG0742	ribosomal rna small subunit methyltransferase
NDY25_RS18745	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NDY25_RS18760	COG3291	Pkd domain containing protein
NDY25_RS18800	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NDY25_RS18805	COG0343	queuine tRNA-ribosyltransferase activity
NDY25_RS18810	COG1862	Preprotein translocase
NDY25_RS18820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NDY25_RS18870	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NDY25_RS18870	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NDY25_RS18875	COG1105	Belongs to the carbohydrate kinase PfkB family
NDY25_RS18880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NDY25_RS18880	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NDY25_RS18885	COG1609	Transcriptional regulator
NDY25_RS18890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NDY25_RS18905	COG2902	Dehydrogenase
NDY25_RS18910	COG0604	alcohol dehydrogenase
NDY25_RS18910	COG3321	synthase
NDY25_RS18920	COG1902	pentaerythritol trinitrate reductase activity
NDY25_RS18930	COG0300	oxidoreductase activity
NDY25_RS18935	COG0604	alcohol dehydrogenase
NDY25_RS18945	COG0477	Major facilitator Superfamily
NDY25_RS18955	COG0784	Response regulator, receiver
NDY25_RS18955	COG5002	protein histidine kinase activity
NDY25_RS18955	COG2205	protein histidine kinase activity
NDY25_RS18960	COG2733	membrane
NDY25_RS18975	COG1121	(ABC) transporter
NDY25_RS18985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NDY25_RS18990	COG2223	nitrite transmembrane transporter activity
NDY25_RS19000	COG0243	molybdopterin cofactor binding
NDY25_RS19010	COG0477	Major facilitator Superfamily
NDY25_RS19020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NDY25_RS19025	COG0174	glutamine synthetase
NDY25_RS19030	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NDY25_RS19065	COG3842	ATPase activity
NDY25_RS19075	COG1176	ABC-type spermidine putrescine transport system, permease component I
NDY25_RS19080	COG1177	transmembrane transport
NDY25_RS19090	COG1012	belongs to the aldehyde dehydrogenase family
NDY25_RS19105	COG4535	Mg2 and Co2 transporter CorC
NDY25_RS19115	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NDY25_RS19125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NDY25_RS19140	COG0741	lytic transglycosylase activity
NDY25_RS19145	COG0723	plastoquinol--plastocyanin reductase activity
NDY25_RS19150	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NDY25_RS19155	COG2857	Cytochrome c1
NDY25_RS19160	COG0625	glutathione transferase activity
NDY25_RS19165	COG2969	positive regulation of protein catabolic process
NDY25_RS19175	COG1201	RNA secondary structure unwinding
NDY25_RS19185	COG0840	transmembrane signaling receptor activity
NDY25_RS19190	COG0835	chemotaxis
NDY25_RS19195	COG2199	diguanylate cyclase activity
NDY25_RS19225	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NDY25_RS19240	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NDY25_RS19245	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NDY25_RS19245	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NDY25_RS19260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NDY25_RS19280	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS19285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NDY25_RS19290	COG0501	Belongs to the peptidase M48B family
NDY25_RS19295	COG3300	MHYT domain
NDY25_RS19295	COG5001	Diguanylate cyclase
NDY25_RS19300	COG2081	HI0933 family
NDY25_RS19305	COG4681	YaeQ
NDY25_RS19310	COG1671	Belongs to the UPF0178 family
NDY25_RS19320	COG0625	glutathione transferase activity
NDY25_RS19330	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NDY25_RS19340	COG0513	Belongs to the DEAD box helicase family
NDY25_RS19345	COG0488	(ABC) transporter
NDY25_RS19360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NDY25_RS19365	COG0483	inositol monophosphate 1-phosphatase activity
NDY25_RS19380	COG3300	MHYT domain
NDY25_RS19380	COG5001	Diguanylate cyclase
NDY25_RS19400	COG0402	S-adenosylhomocysteine deaminase activity
NDY25_RS19405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NDY25_RS19465	COG4302	ethanolamine ammonia-lyase activity
NDY25_RS19470	COG4303	Ethanolamine ammonia lyase large subunit
NDY25_RS19485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NDY25_RS19505	COG2166	iron-sulfur cluster assembly
NDY25_RS19510	COG0215	cysteine-tRNA ligase activity
NDY25_RS19520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NDY25_RS19525	COG0137	argininosuccinate synthase activity
NDY25_RS19530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NDY25_RS19535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NDY25_RS19550	COG0165	Argininosuccinate lyase
NDY25_RS19565	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NDY25_RS19595	COG1294	oxidase, subunit
NDY25_RS19605	COG4988	ABC transporter
NDY25_RS19610	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NDY25_RS19650	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NDY25_RS19675	COG0436	Aminotransferase
NDY25_RS19680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NDY25_RS19695	COG1187	pseudouridine synthase activity
NDY25_RS19700	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NDY25_RS19705	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NDY25_RS19710	COG2350	Protein conserved in bacteria
NDY25_RS19735	COG1653	transport
NDY25_RS19740	COG1175	transmembrane transport
NDY25_RS19745	COG0395	ABC-type sugar transport system, permease component
NDY25_RS19770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NDY25_RS19775	COG2957	Belongs to the agmatine deiminase family
NDY25_RS19790	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NDY25_RS19810	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NDY25_RS19815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NDY25_RS19825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NDY25_RS19830	COG0475	glutathione-regulated potassium exporter activity
NDY25_RS19830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NDY25_RS19840	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NDY25_RS19855	COG0582	viral genome integration into host DNA
NDY25_RS19915	COG3039	Transposase
NDY25_RS19985	COG0840	transmembrane signaling receptor activity
NDY25_RS20005	COG2205	protein histidine kinase activity
NDY25_RS20005	COG5002	protein histidine kinase activity
NDY25_RS20005	COG0784	Response regulator, receiver
NDY25_RS20010	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NDY25_RS20015	COG4191	Histidine kinase
NDY25_RS20015	COG0784	Response regulator, receiver
NDY25_RS20030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDY25_RS20040	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NDY25_RS20050	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NDY25_RS20115	COG2244	polysaccharide biosynthetic process
NDY25_RS20145	COG2264	protein methyltransferase activity
NDY25_RS20150	COG0297	glycogen (starch) synthase activity
NDY25_RS20155	COG0438	transferase activity, transferring glycosyl groups
NDY25_RS20170	COG1136	(ABC) transporter
NDY25_RS20175	COG1132	(ABC) transporter
NDY25_RS20180	COG0477	Major facilitator Superfamily
NDY25_RS20185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDY25_RS20200	COG1253	flavin adenine dinucleotide binding
NDY25_RS20235	COG0504	CTP synthase activity
NDY25_RS20250	COG0148	phosphopyruvate hydratase activity
NDY25_RS20255	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NDY25_RS20260	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NDY25_RS20265	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NDY25_RS20275	COG2840	Smr protein MutS2
NDY25_RS20280	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NDY25_RS20285	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NDY25_RS20290	COG1238	metal cluster binding
NDY25_RS20305	COG1534	Rna-binding protein
NDY25_RS20310	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NDY25_RS20320	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NDY25_RS20325	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NDY25_RS20335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NDY25_RS20340	COG1546	Belongs to the CinA family
NDY25_RS20345	COG4771	TonB-dependent receptor
NDY25_RS20350	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NDY25_RS20360	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NDY25_RS20365	COG2137	regulation of response to DNA damage stimulus
NDY25_RS20370	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NDY25_RS20375	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NDY25_RS20390	COG1741	Belongs to the pirin family
NDY25_RS20395	COG0583	DNA-binding transcription factor activity
NDY25_RS20415	COG0352	thiamine-phosphate diphosphorylase activity
NDY25_RS20415	COG0351	phosphomethylpyrimidine kinase
NDY25_RS20430	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NDY25_RS20435	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NDY25_RS20450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NDY25_RS20460	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NDY25_RS20475	COG4948	Mandelate Racemase Muconate Lactonizing
NDY25_RS20480	COG0800	Aldolase
NDY25_RS20515	COG1501	Belongs to the glycosyl hydrolase 31 family
NDY25_RS20525	COG1070	Carbohydrate kinase
NDY25_RS20530	COG2115	Belongs to the xylose isomerase family
NDY25_RS20535	COG0477	Major facilitator Superfamily
NDY25_RS20555	COG0860	N-Acetylmuramoyl-L-alanine amidase
NDY25_RS20580	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NDY25_RS20585	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NDY25_RS20615	COG1472	Belongs to the glycosyl hydrolase 3 family
NDY25_RS20625	COG2203	Gaf domain
NDY25_RS20625	COG3706	GGDEF domain
NDY25_RS20625	COG4251	negative regulation of phosphorylation
NDY25_RS20625	COG5001	Diguanylate cyclase
NDY25_RS20630	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NDY25_RS20635	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NDY25_RS20645	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NDY25_RS20650	COG0671	phosphoesterase, PA-phosphatase related
NDY25_RS20670	COG0697	spore germination
NDY25_RS20675	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NDY25_RS20680	COG0167	dihydroorotate dehydrogenase activity
NDY25_RS20695	COG1012	belongs to the aldehyde dehydrogenase family
NDY25_RS20705	COG3209	COG3209 Rhs family protein
NDY25_RS20730	COG3039	Transposase
NDY25_RS20745	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NDY25_RS20750	COG0460	homoserine dehydrogenase
NDY25_RS20750	COG0527	aspartate kinase activity
NDY25_RS20780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NDY25_RS20795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NDY25_RS20800	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NDY25_RS20805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NDY25_RS20810	COG0131	Imidazoleglycerol-phosphate dehydratase
NDY25_RS20810	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NDY25_RS20820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NDY25_RS20825	COG0107	imidazoleglycerol-phosphate synthase activity
NDY25_RS20830	COG0140	phosphoribosyl-ATP diphosphatase activity
NDY25_RS20830	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NDY25_RS20845	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
NDY25_RS20860	COG0531	amino acid
NDY25_RS20865	COG0531	amino acid
NDY25_RS20875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NDY25_RS20880	COG0277	FAD linked oxidase domain protein
NDY25_RS20900	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NDY25_RS20915	COG1024	Enoyl-CoA hydratase
NDY25_RS20935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NDY25_RS20945	COG0505	Belongs to the CarA family
NDY25_RS20955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NDY25_RS20960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NDY25_RS20970	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NDY25_RS20995	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NDY25_RS21005	COG2205	protein histidine kinase activity
NDY25_RS21005	COG2198	Histidine kinase
NDY25_RS21005	COG0784	Response regulator, receiver
NDY25_RS21010	COG2205	protein histidine kinase activity
NDY25_RS21010	COG2198	Histidine kinase
NDY25_RS21010	COG0784	Response regulator, receiver
NDY25_RS21015	COG1024	Enoyl-CoA hydratase
NDY25_RS21020	COG0318	PFAM AMP-dependent synthetase and ligase
NDY25_RS21065	COG2201	protein-glutamate methylesterase activity
NDY25_RS21080	COG0840	transmembrane signaling receptor activity
NDY25_RS21090	COG0835	chemotaxis
NDY25_RS21100	COG0840	transmembrane signaling receptor activity
NDY25_RS21105	COG0840	transmembrane signaling receptor activity
NDY25_RS21120	COG0840	transmembrane signaling receptor activity
NDY25_RS21125	COG0840	transmembrane signaling receptor activity
NDY25_RS21130	COG0840	transmembrane signaling receptor activity
NDY25_RS21135	COG0840	transmembrane signaling receptor activity
NDY25_RS21135	COG0840	transmembrane signaling receptor activity
NDY25_RS21145	COG0840	transmembrane signaling receptor activity
NDY25_RS21155	COG2198	Histidine kinase
NDY25_RS21155	COG0643	Histidine kinase
NDY25_RS21160	COG0745	RESPONSE REGULATOR receiver
NDY25_RS21170	COG0835	chemotaxis
NDY25_RS21175	COG1192	Involved in chromosome partitioning
NDY25_RS21185	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NDY25_RS21210	COG4771	TonB-dependent receptor
NDY25_RS21240	COG1169	isochorismate synthase
NDY25_RS21270	COG2226	methyltransferase
NDY25_RS21270	COG3433	isochorismatase activity
NDY25_RS21270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDY25_RS21275	COG3321	synthase
NDY25_RS21275	COG0604	alcohol dehydrogenase
NDY25_RS21290	COG2226	methyltransferase
NDY25_RS21290	COG3433	isochorismatase activity
NDY25_RS21290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDY25_RS21305	COG4771	TonB-dependent receptor
NDY25_RS21315	COG2375	cellular response to nickel ion
NDY25_RS21315	COG1132	(ABC) transporter
NDY25_RS21320	COG1132	(ABC) transporter
NDY25_RS21325	COG1132	(ABC) transporter
NDY25_RS21330	COG2198	Histidine kinase
NDY25_RS21330	COG0784	Response regulator, receiver
NDY25_RS21330	COG0643	Histidine kinase
NDY25_RS21380	COG3300	MHYT domain
NDY25_RS21380	COG5001	Diguanylate cyclase
NDY25_RS21400	COG3190	flagellar
NDY25_RS21450	COG1677	Flagellar hook-basal body complex protein FliE
NDY25_RS21470	COG3039	Transposase
NDY25_RS21500	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_RS21505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NDY25_RS21525	COG2201	protein-glutamate methylesterase activity
NDY25_RS21555	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NDY25_RS21560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NDY25_RS21575	COG1705	Flagellar rod assembly protein muramidase FlgJ
NDY25_RS21575	COG3951	Flagellar rod assembly protein muramidase FlgJ
NDY25_RS21595	COG4787	bacterial-type flagellum-dependent cell motility
NDY25_RS21605	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NDY25_RS21610	COG1558	bacterial-type flagellum-dependent cell motility
NDY25_RS21620	COG0784	Response regulator, receiver
NDY25_RS21620	COG0835	chemotaxis
NDY25_RS21640	COG4191	Histidine kinase
NDY25_RS21680	COG0482	sulfurtransferase activity
NDY25_RS21695	COG0542	response to heat
NDY25_RS21705	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NDY25_RS21715	COG0492	ferredoxin-NADP+ reductase activity
NDY25_RS21720	COG1674	ftsk spoiiie
NDY25_RS21735	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NDY25_RS21740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NDY25_RS21745	COG0183	Belongs to the thiolase family
NDY25_RS21750	COG1250	3-hydroxyacyl-CoA dehydrogenase
NDY25_RS21750	COG1024	Enoyl-CoA hydratase
NDY25_RS21765	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NDY25_RS21775	COG1426	Protein conserved in bacteria
NDY25_RS21785	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NDY25_RS21790	COG1160	GTP binding
NDY25_RS21795	COG0303	'Molybdopterin
NDY25_RS21800	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NDY25_RS21810	COG0708	Exodeoxyribonuclease III
NDY25_RS21820	COG0303	'Molybdopterin
NDY25_RS21825	COG0746	molybdenum cofactor guanylyltransferase activity
NDY25_RS21835	COG1648	precorrin-2 dehydrogenase activity
NDY25_RS21835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NDY25_RS21845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NDY25_RS21850	COG2223	nitrite transmembrane transporter activity
NDY25_RS21855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NDY25_RS21865	COG0243	molybdopterin cofactor binding
NDY25_RS21885	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NDY25_RS21895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NDY25_RS21905	COG0579	oxidoreductase
NDY25_RS21925	COG3685	Protein conserved in bacteria
NDY25_RS21940	COG5001	Diguanylate cyclase
NDY25_RS21960	COG2205	protein histidine kinase activity
NDY25_RS21975	COG3713	MltA-interacting MipA family protein
NDY25_RS22015	COG4191	Histidine kinase
NDY25_RS22015	COG0784	Response regulator, receiver
NDY25_RS22050	COG3781	membrane
NDY25_RS22055	COG4191	Histidine kinase
NDY25_RS22060	COG2197	response regulator
NDY25_RS22090	COG0840	transmembrane signaling receptor activity
NDY25_RS22135	COG0488	(ABC) transporter
NDY25_RS22430	COG0551	DNA topoisomerase type I activity
NDY25_RS22430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NDY25_RS22485	COG3846	protein secretion by the type IV secretion system
NDY25_RS22500	COG3451	type IV secretory pathway VirB4
NDY25_RS22505	COG3451	type IV secretory pathway VirB4
NDY25_RS22525	COG4644	lycopene metabolic process
NDY25_RS22580	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NDY25_RS22595	COG0653	protein targeting
NDY25_RS22810	COG4962	Type ii secretion system protein e