locus-tag	class	description
EYC57_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EYC57_RS00025	COG0187	DNA topoisomerase II activity
EYC57_RS00035	COG0501	Belongs to the peptidase M48B family
EYC57_RS00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EYC57_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYC57_RS00115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYC57_RS00125	COG0793	Belongs to the peptidase S41A family
EYC57_RS00130	COG4942	peptidase
EYC57_RS00140	COG2234	aminopeptidase activity
EYC57_RS00150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYC57_RS00165	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYC57_RS00175	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYC57_RS00185	COG1064	alcohol dehydrogenase
EYC57_RS00200	COG0493	'glutamate synthase
EYC57_RS00205	COG0070	glutamate synthase
EYC57_RS00205	COG0069	glutamate synthase activity
EYC57_RS00205	COG0067	glutamate synthase
EYC57_RS00265	COG1205	dead DEAH box helicase
EYC57_RS00265	COG1111	helicase
EYC57_RS00270	COG1272	protein, Hemolysin III
EYC57_RS00290	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EYC57_RS00300	COG4772	TonB-dependent receptor
EYC57_RS00310	COG3039	Transposase
EYC57_RS00315	COG1304	FMN binding
EYC57_RS00350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYC57_RS00385	COG0477	Major facilitator Superfamily
EYC57_RS00395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC57_RS00435	COG3237	CsbD-like
EYC57_RS00490	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EYC57_RS00495	COG1074	ATP-dependent DNA helicase activity
EYC57_RS00500	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EYC57_RS00565	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS00610	COG0564	pseudouridine synthase activity
EYC57_RS00640	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS00680	COG0477	Major facilitator Superfamily
EYC57_RS00790	COG0302	gtp cyclohydrolase
EYC57_RS00820	COG0730	response to heat
EYC57_RS00835	COG0676	glucose-6-phosphate 1-epimerase activity
EYC57_RS00855	COG3135	benzoate transporter
EYC57_RS00885	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EYC57_RS00900	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EYC57_RS00915	COG0210	DNA helicase
EYC57_RS00930	COG3132	Protein of unknown function, DUF480
EYC57_RS00935	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EYC57_RS00940	COG0284	orotidine-5'-phosphate decarboxylase activity
EYC57_RS00975	COG2937	Belongs to the GPAT DAPAT family
EYC57_RS01020	COG2211	Major facilitator Superfamily
EYC57_RS01045	COG3693	PFAM glycoside hydrolase, family 10
EYC57_RS01080	COG0084	hydrolase, TatD family'
EYC57_RS01100	COG0583	DNA-binding transcription factor activity
EYC57_RS01105	COG2814	Major facilitator Superfamily
EYC57_RS01115	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EYC57_RS01120	COG1902	pentaerythritol trinitrate reductase activity
EYC57_RS01170	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYC57_RS01175	COG0583	DNA-binding transcription factor activity
EYC57_RS01205	COG0702	epimerase
EYC57_RS01210	COG1733	regulation of RNA biosynthetic process
EYC57_RS01240	COG1609	Transcriptional regulator
EYC57_RS01265	COG0366	Alpha amylase catalytic
EYC57_RS01270	COG0366	Alpha amylase catalytic
EYC57_RS01280	COG2831	hemolysin activation secretion protein
EYC57_RS01325	COG3210	domain, Protein
EYC57_RS01390	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS01425	COG3039	Transposase
EYC57_RS01505	COG0656	L-ascorbic acid biosynthetic process
EYC57_RS01510	COG2130	NADP-dependent
EYC57_RS01515	COG0667	Aldo Keto reductase
EYC57_RS01525	COG1187	pseudouridine synthase activity
EYC57_RS01540	COG1643	Atp-dependent helicase
EYC57_RS01550	COG4807	Protein conserved in bacteria
EYC57_RS01555	COG2072	flavoprotein involved in K transport
EYC57_RS01575	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EYC57_RS01625	COG3039	Transposase
EYC57_RS01640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYC57_RS01670	COG3228	Belongs to the MtfA family
EYC57_RS01680	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EYC57_RS01680	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EYC57_RS01685	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EYC57_RS01700	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EYC57_RS01740	COG3237	CsbD-like
EYC57_RS01745	COG0180	Tryptophanyl-tRNA synthetase
EYC57_RS01750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYC57_RS01775	COG0697	spore germination
EYC57_RS01800	COG0753	catalase activity
EYC57_RS01805	COG1595	DNA-templated transcription, initiation
EYC57_RS01815	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EYC57_RS01850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYC57_RS01870	COG1090	epimerase
EYC57_RS01915	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EYC57_RS01935	COG0606	chelatase, subunit chli
EYC57_RS01980	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EYC57_RS01985	COG1166	arginine decarboxylase activity
EYC57_RS02005	COG2755	lipolytic protein G-D-S-L family
EYC57_RS02005	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EYC57_RS02010	COG4221	oxidoreductase activity
EYC57_RS02035	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EYC57_RS02060	COG0463	Glycosyl transferase, family 2
EYC57_RS02075	COG1475	DNA binding
EYC57_RS02080	COG1192	Involved in chromosome partitioning
EYC57_RS02095	COG0708	Exodeoxyribonuclease III
EYC57_RS02105	COG2211	Major facilitator Superfamily
EYC57_RS02120	COG0739	heme binding
EYC57_RS02175	COG3186	Phenylalanine-4-hydroxylase
EYC57_RS02180	COG1522	sequence-specific DNA binding
EYC57_RS02185	COG4773	Receptor
EYC57_RS02190	COG1752	Esterase of the alpha-beta hydrolase superfamily
EYC57_RS02195	COG1473	amidohydrolase
EYC57_RS02205	COG1119	ATPase activity
EYC57_RS02220	COG0517	IMP dehydrogenase activity
EYC57_RS02220	COG1125	glycine betaine transport
EYC57_RS02235	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYC57_RS02240	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EYC57_RS02245	COG3550	peptidyl-serine autophosphorylation
EYC57_RS02250	COG1396	sequence-specific DNA binding
EYC57_RS02270	COG0489	protein tyrosine kinase activity
EYC57_RS02275	COG2062	phosphohistidine phosphatase, SixA
EYC57_RS02285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYC57_RS02335	COG1968	undecaprenyl-diphosphatase activity
EYC57_RS02340	COG0174	glutamine synthetase
EYC57_RS02345	COG0347	Belongs to the P(II) protein family
EYC57_RS02350	COG0004	ammonium transporteR
EYC57_RS02355	COG3852	Histidine kinase
EYC57_RS02360	COG2204	response regulator
EYC57_RS02370	COG2032	superoxide dismutase activity
EYC57_RS02375	COG2032	superoxide dismutase activity
EYC57_RS02400	COG0129	dihydroxy-acid dehydratase activity
EYC57_RS02410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EYC57_RS02490	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EYC57_RS02495	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EYC57_RS02505	COG3485	protocatechuate 3,4-dioxygenase
EYC57_RS02510	COG3485	protocatechuate 3,4-dioxygenase
EYC57_RS02525	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYC57_RS02530	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYC57_RS02545	COG1414	Transcriptional regulator
EYC57_RS02555	COG0657	acetylesterase activity
EYC57_RS02565	COG3541	Predicted nucleotidyltransferase
EYC57_RS02585	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYC57_RS02625	COG0156	8-amino-7-oxononanoate synthase activity
EYC57_RS02630	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EYC57_RS02635	COG1040	competence protein
EYC57_RS02640	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EYC57_RS02735	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYC57_RS02810	COG3264	Mechanosensitive ion channel
EYC57_RS02810	COG1511	domain protein
EYC57_RS02825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EYC57_RS02835	COG2354	Protein conserved in bacteria
EYC57_RS02840	COG1649	PFAM Uncharacterised BCR, COG1649
EYC57_RS02860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EYC57_RS02885	COG0702	epimerase
EYC57_RS02895	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS02965	COG1063	alcohol dehydrogenase
EYC57_RS02990	COG1294	oxidase, subunit
EYC57_RS02995	COG1271	oxidase subunit
EYC57_RS03010	COG2204	response regulator
EYC57_RS03040	COG3546	catalase activity
EYC57_RS03045	COG3685	Protein conserved in bacteria
EYC57_RS03065	COG2972	Histidine kinase
EYC57_RS03085	COG0531	amino acid
EYC57_RS03105	COG3590	peptidase
EYC57_RS03120	COG0667	Aldo Keto reductase
EYC57_RS03135	COG3384	dioxygenase
EYC57_RS03145	COG1573	uracil-dna glycosylase
EYC57_RS03155	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EYC57_RS03165	COG0025	NhaP-type Na H and K H
EYC57_RS03170	COG1131	(ABC) transporter
EYC57_RS03175	COG0842	Transport permease protein
EYC57_RS03190	COG1404	Belongs to the peptidase S8 family
EYC57_RS03205	COG0745	RESPONSE REGULATOR receiver
EYC57_RS03255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC57_RS03280	COG2202	Pas domain
EYC57_RS03280	COG2205	protein histidine kinase activity
EYC57_RS03310	COG2813	Specifically methylates the guanine in position
EYC57_RS03315	COG1187	pseudouridine synthase activity
EYC57_RS03320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYC57_RS03355	COG3039	Transposase
EYC57_RS03380	COG0697	spore germination
EYC57_RS03390	COG2011	ABC-type metal ion transport system permease component
EYC57_RS03430	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYC57_RS03440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYC57_RS03460	COG0356	it plays a direct role in the translocation of protons across the membrane
EYC57_RS03470	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EYC57_RS03480	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EYC57_RS03485	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EYC57_RS03490	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EYC57_RS03540	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYC57_RS03585	COG0339	signal peptide processing
EYC57_RS03615	COG0546	phosphoglycolate phosphatase activity
EYC57_RS03625	COG1956	GAF domain-containing protein
EYC57_RS03630	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EYC57_RS03640	COG0720	synthase
EYC57_RS03650	COG0513	Belongs to the DEAD box helicase family
EYC57_RS03665	COG0625	glutathione transferase activity
EYC57_RS03700	COG0626	cystathionine gamma-synthase activity
EYC57_RS03720	COG0438	transferase activity, transferring glycosyl groups
EYC57_RS03720	COG1216	Glycosyl transferase, family 2
EYC57_RS03740	COG2963	transposase activity
EYC57_RS03765	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EYC57_RS03770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYC57_RS03785	COG0277	FAD linked oxidase domain protein
EYC57_RS03790	COG0546	phosphoglycolate phosphatase activity
EYC57_RS03790	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EYC57_RS03805	COG2086	electron transfer activity
EYC57_RS03830	COG0662	Cupin 2, conserved barrel domain protein
EYC57_RS03830	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EYC57_RS03835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYC57_RS03845	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EYC57_RS03875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EYC57_RS03875	COG3218	ABC-type transport auxiliary lipoprotein component
EYC57_RS03880	COG1127	ABC transporter
EYC57_RS03885	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EYC57_RS03900	COG0442	prolyl-tRNA aminoacylation
EYC57_RS03910	COG1183	phosphatidylcholine synthase activity
EYC57_RS03940	COG0525	valine-tRNA ligase activity
EYC57_RS03965	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EYC57_RS03975	COG0795	lipopolysaccharide-transporting ATPase activity
EYC57_RS03995	COG4974	Belongs to the 'phage' integrase family
EYC57_RS04000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EYC57_RS04010	COG0047	phosphoribosylformylglycinamidine synthase activity
EYC57_RS04010	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EYC57_RS04020	COG5295	Hep Hag repeat protein
EYC57_RS04025	COG1404	Belongs to the peptidase S8 family
EYC57_RS04030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EYC57_RS04040	COG1459	type II secretion system
EYC57_RS04045	COG2165	general secretion pathway protein
EYC57_RS04050	COG4970	Tfp pilus assembly protein FimT
EYC57_RS04055	COG2165	general secretion pathway protein
EYC57_RS04060	COG4795	General secretion pathway protein
EYC57_RS04065	COG3156	type II secretion system protein K
EYC57_RS04070	COG3166	PFAM Fimbrial assembly family protein
EYC57_RS04085	COG1450	Type ii and iii secretion system protein
EYC57_RS04100	COG2188	Transcriptional regulator
EYC57_RS04155	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EYC57_RS04175	COG0242	peptide deformylase activity
EYC57_RS04215	COG0402	S-adenosylhomocysteine deaminase activity
EYC57_RS04220	COG3964	amidohydrolase
EYC57_RS04240	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EYC57_RS04245	COG0726	polysaccharide deacetylase
EYC57_RS04265	COG0436	Aminotransferase
EYC57_RS04295	COG2211	Major facilitator Superfamily
EYC57_RS04305	COG1609	Transcriptional regulator
EYC57_RS04310	COG1028	Short-chain dehydrogenase reductase Sdr
EYC57_RS04315	COG2851	Citrate transporter
EYC57_RS04335	COG0642	Histidine kinase
EYC57_RS04345	COG2197	response regulator
EYC57_RS04365	COG0583	DNA-binding transcription factor activity
EYC57_RS04380	COG4191	Histidine kinase
EYC57_RS04400	COG0280	phosphate acetyltransferase
EYC57_RS04400	COG0281	malic enzyme
EYC57_RS04430	COG1560	Kdo2-lipid A biosynthetic process
EYC57_RS04435	COG1519	Transferase
EYC57_RS04440	COG1538	Outer membrane efflux protein
EYC57_RS04445	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EYC57_RS04465	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EYC57_RS04470	COG0066	3-isopropylmalate dehydratase activity
EYC57_RS04475	COG2226	methyltransferase
EYC57_RS04505	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EYC57_RS04515	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EYC57_RS04520	COG3710	Transcriptional regulator
EYC57_RS04545	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EYC57_RS04555	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EYC57_RS04580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYC57_RS04590	COG3781	membrane
EYC57_RS04600	COG0671	phosphoesterase, PA-phosphatase related
EYC57_RS04610	COG1028	Short-chain dehydrogenase reductase Sdr
EYC57_RS04625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYC57_RS04630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYC57_RS04670	COG2197	response regulator
EYC57_RS04680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EYC57_RS04700	COG0352	thiamine-phosphate diphosphorylase activity
EYC57_RS04705	COG1773	rubredoxin
EYC57_RS04710	COG2912	Transglutaminase-like superfamily
EYC57_RS04730	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EYC57_RS04755	COG0006	proline dipeptidase activity
EYC57_RS04785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYC57_RS04795	COG0346	lactoylglutathione lyase activity
EYC57_RS04800	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EYC57_RS04805	COG1561	YicC-like family, N-terminal region
EYC57_RS04825	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYC57_RS04835	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EYC57_RS04865	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EYC57_RS04900	COG0714	Associated with various cellular activities
EYC57_RS04920	COG2304	oxidoreductase activity
EYC57_RS04940	COG1301	dicarboxylic acid transport
EYC57_RS04945	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EYC57_RS04960	COG0739	heme binding
EYC57_RS04965	COG1376	ErfK ybiS ycfS ynhG family protein
EYC57_RS04995	COG3039	Transposase
EYC57_RS05030	COG0642	Histidine kinase
EYC57_RS05050	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EYC57_RS05055	COG4149	molybdate abc transporter
EYC57_RS05060	COG0725	ABC transporter, periplasmic molybdate-binding protein
EYC57_RS05065	COG3453	Protein conserved in bacteria
EYC57_RS05065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYC57_RS05075	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EYC57_RS05100	COG0469	pyruvate kinase activity
EYC57_RS05110	COG3588	fructose-bisphosphate aldolase
EYC57_RS05115	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EYC57_RS05170	COG0784	Response regulator, receiver
EYC57_RS05170	COG2205	protein histidine kinase activity
EYC57_RS05170	COG2198	Histidine kinase
EYC57_RS05195	COG0175	sulfate reduction
EYC57_RS05200	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EYC57_RS05205	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYC57_RS05210	COG0175	sulfate reduction
EYC57_RS05215	COG2895	sulfate adenylyltransferase (ATP) activity
EYC57_RS05215	COG0529	Catalyzes the synthesis of activated sulfate
EYC57_RS05225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC57_RS05230	COG0308	aminopeptidase N
EYC57_RS05250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYC57_RS05265	COG1970	mechanosensitive ion channel activity
EYC57_RS05295	COG3273	potassium ion transport
EYC57_RS05295	COG0471	metal ion transport
EYC57_RS05310	COG2022	thiamine diphosphate biosynthetic process
EYC57_RS05370	COG3039	Transposase
EYC57_RS05375	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS05410	COG0745	RESPONSE REGULATOR receiver
EYC57_RS05415	COG2205	protein histidine kinase activity
EYC57_RS05420	COG0237	dephospho-CoA kinase activity
EYC57_RS05425	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EYC57_RS05440	COG2194	sulfuric ester hydrolase activity
EYC57_RS05475	COG0045	succinate-CoA ligase (ADP-forming) activity
EYC57_RS05480	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EYC57_RS05495	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EYC57_RS05495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYC57_RS05500	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC57_RS05505	COG0564	pseudouridine synthase activity
EYC57_RS05520	COG3011	Protein conserved in bacteria
EYC57_RS05540	COG3387	PFAM Glycoside hydrolase 15-related
EYC57_RS05545	COG1877	trehalose-phosphatase activity
EYC57_RS05585	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EYC57_RS05600	COG1595	DNA-templated transcription, initiation
EYC57_RS05610	COG1946	Acyl-CoA thioesterase
EYC57_RS05625	COG0824	Thioesterase
EYC57_RS05630	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EYC57_RS05640	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EYC57_RS05645	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EYC57_RS05650	COG0268	Binds directly to 16S ribosomal RNA
EYC57_RS05655	COG0728	peptidoglycan biosynthetic process
EYC57_RS05660	COG0196	riboflavin kinase activity
EYC57_RS05670	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EYC57_RS05675	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EYC57_RS05690	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYC57_RS05695	COG1845	cytochrome c oxidase, subunit III
EYC57_RS05700	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EYC57_RS05720	COG3209	COG3209 Rhs family protein
EYC57_RS05780	COG2207	Transcriptional regulator
EYC57_RS05785	COG0326	Molecular chaperone. Has ATPase activity
EYC57_RS05795	COG1366	Belongs to the anti-sigma-factor antagonist family
EYC57_RS05800	COG1366	Belongs to the anti-sigma-factor antagonist family
EYC57_RS05805	COG2172	sigma factor antagonist activity
EYC57_RS05845	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYC57_RS05855	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EYC57_RS05890	COG3039	Transposase
EYC57_RS05935	COG3179	chitinase
EYC57_RS06060	COG3039	Transposase
EYC57_RS06215	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EYC57_RS06230	COG1842	Phage shock protein A
EYC57_RS06255	COG0754	glutathionylspermidine amidase activity
EYC57_RS06325	COG0531	amino acid
EYC57_RS06330	COG2197	response regulator
EYC57_RS06335	COG2267	carboxylic ester hydrolase activity
EYC57_RS06345	COG1113	amino acid transport
EYC57_RS06355	COG1271	oxidase subunit
EYC57_RS06360	COG1294	oxidase, subunit
EYC57_RS06370	COG2239	Acts as a magnesium transporter
EYC57_RS06380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYC57_RS06385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYC57_RS06395	COG1660	Displays ATPase and GTPase activities
EYC57_RS06405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYC57_RS06420	COG1137	ATPase activity
EYC57_RS06425	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EYC57_RS06435	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EYC57_RS06445	COG0271	Belongs to the BolA IbaG family
EYC57_RS06450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYC57_RS06475	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EYC57_RS06490	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EYC57_RS06500	COG0628	permease
EYC57_RS06510	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EYC57_RS06515	COG3178	'Phosphotransferase
EYC57_RS06530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYC57_RS06535	COG1555	photosystem II stabilization
EYC57_RS06550	COG2146	nitrite reductase [NAD(P)H] activity
EYC57_RS06560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EYC57_RS06565	COG0719	Fe-S assembly protein
EYC57_RS06570	COG0396	ATPase activity
EYC57_RS06575	COG0719	Fe-S assembly protein
EYC57_RS06580	COG1959	2 iron, 2 sulfur cluster binding
EYC57_RS06600	COG0693	protein deglycase activity
EYC57_RS06635	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EYC57_RS06665	COG0519	Catalyzes the synthesis of GMP from XMP
EYC57_RS06680	COG1678	Uncharacterized ACR, COG1678
EYC57_RS06685	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EYC57_RS06700	COG1764	response to oxidative stress
EYC57_RS06710	COG0384	phenazine biosynthesis protein PhzF
EYC57_RS06720	COG0527	aspartate kinase activity
EYC57_RS06750	COG0142	geranyltranstransferase activity
EYC57_RS06755	COG0629	single-stranded DNA binding
EYC57_RS06760	COG5001	Diguanylate cyclase
EYC57_RS06760	COG4251	negative regulation of phosphorylation
EYC57_RS06760	COG3706	GGDEF domain
EYC57_RS06760	COG2203	Gaf domain
EYC57_RS06770	COG2080	2 iron, 2 sulfur cluster binding
EYC57_RS06775	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EYC57_RS06780	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EYC57_RS06785	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EYC57_RS06840	COG2879	small protein
EYC57_RS06845	COG1966	Carbon starvation protein
EYC57_RS06850	COG1741	Belongs to the pirin family
EYC57_RS06880	COG1741	Belongs to the pirin family
EYC57_RS06890	COG1515	deoxyribonuclease V activity
EYC57_RS06920	COG3409	Peptidoglycan-binding domain 1 protein
EYC57_RS06920	COG3501	Rhs element vgr protein
EYC57_RS06935	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EYC57_RS06940	COG2199	diguanylate cyclase activity
EYC57_RS06940	COG2200	EAL domain
EYC57_RS06940	COG2202	Pas domain
EYC57_RS06945	COG0835	chemotaxis
EYC57_RS06950	COG0840	transmembrane signaling receptor activity
EYC57_RS06960	COG0643	Histidine kinase
EYC57_RS06960	COG2198	Histidine kinase
EYC57_RS06970	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EYC57_RS06980	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EYC57_RS07020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYC57_RS07025	COG0735	belongs to the Fur family
EYC57_RS07160	COG5002	protein histidine kinase activity
EYC57_RS07160	COG5001	Diguanylate cyclase
EYC57_RS07165	COG1187	pseudouridine synthase activity
EYC57_RS07185	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EYC57_RS07195	COG0475	glutathione-regulated potassium exporter activity
EYC57_RS07200	COG5000	phosphorelay sensor kinase activity
EYC57_RS07200	COG5002	protein histidine kinase activity
EYC57_RS07205	COG0745	RESPONSE REGULATOR receiver
EYC57_RS07235	COG1132	(ABC) transporter
EYC57_RS07300	COG3118	belongs to the thioredoxin family
EYC57_RS07330	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EYC57_RS07355	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EYC57_RS07385	COG2968	Membrane
EYC57_RS07400	COG3164	Protein of unknown function
EYC57_RS07410	COG0312	modulator of DNA gyrase
EYC57_RS07420	COG0312	modulator of DNA gyrase
EYC57_RS07435	COG4104	PAAR repeat-containing protein
EYC57_RS07440	COG0142	geranyltranstransferase activity
EYC57_RS07445	COG1722	exodeoxyribonuclease VII activity
EYC57_RS07450	COG0037	tRNA processing
EYC57_RS07455	COG1785	Belongs to the alkaline phosphatase family
EYC57_RS07460	COG1301	dicarboxylic acid transport
EYC57_RS07465	COG4106	trans-aconitate 2-methyltransferase activity
EYC57_RS07480	COG0791	NLP P60 protein
EYC57_RS07485	COG0791	NLP P60 protein
EYC57_RS07490	COG1047	Peptidyl-prolyl cis-trans
EYC57_RS07495	COG2311	Membrane
EYC57_RS07500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC57_RS07575	COG3039	Transposase
EYC57_RS07580	COG0489	protein tyrosine kinase activity
EYC57_RS07590	COG0717	Belongs to the dCTP deaminase family
EYC57_RS07620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYC57_RS07625	COG3039	Transposase
EYC57_RS07645	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYC57_RS07655	COG0840	transmembrane signaling receptor activity
EYC57_RS07695	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EYC57_RS07700	COG0084	hydrolase, TatD family'
EYC57_RS07715	COG1960	acyl-CoA dehydrogenase activity
EYC57_RS07730	COG0367	asparagine synthase
EYC57_RS07740	COG0305	Participates in initiation and elongation during chromosome replication
EYC57_RS07745	COG0415	Belongs to the DNA photolyase family
EYC57_RS07765	COG1028	Short-chain dehydrogenase reductase Sdr
EYC57_RS07785	COG3706	GGDEF domain
EYC57_RS07800	COG0174	glutamine synthetase
EYC57_RS07805	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EYC57_RS07810	COG1280	lysine exporter protein (LysE YggA)
EYC57_RS07815	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EYC57_RS07830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EYC57_RS07860	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EYC57_RS07870	COG2914	Belongs to the UPF0125 (RnfH) family
EYC57_RS07880	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC57_RS07890	COG0497	DNA recombination
EYC57_RS07900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EYC57_RS07905	COG0443	Heat shock 70 kDa protein
EYC57_RS07910	COG0484	heat shock protein binding
EYC57_RS07920	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EYC57_RS07950	COG0583	DNA-binding transcription factor activity
EYC57_RS07960	COG1132	(ABC) transporter
EYC57_RS07995	COG2850	peptidyl-arginine hydroxylation
EYC57_RS08020	COG1253	flavin adenine dinucleotide binding
EYC57_RS08055	COG1131	(ABC) transporter
EYC57_RS08060	COG1725	Transcriptional regulator
EYC57_RS08070	COG0386	Belongs to the glutathione peroxidase family
EYC57_RS08085	COG2900	Belongs to the SlyX family
EYC57_RS08100	COG1609	Transcriptional regulator
EYC57_RS08110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYC57_RS08120	COG1410	methionine synthase
EYC57_RS08120	COG0646	methionine synthase
EYC57_RS08125	COG0646	methionine synthase
EYC57_RS08125	COG1410	methionine synthase
EYC57_RS08130	COG2226	methyltransferase
EYC57_RS08135	COG1960	acyl-CoA dehydrogenase activity
EYC57_RS08165	COG0557	exoribonuclease II activity
EYC57_RS08180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYC57_RS08190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EYC57_RS08200	COG0704	Plays a role in the regulation of phosphate uptake
EYC57_RS08215	COG0573	inorganic phosphate transmembrane transporter activity
EYC57_RS08220	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EYC57_RS08245	COG0659	secondary active sulfate transmembrane transporter activity
EYC57_RS08250	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EYC57_RS08260	COG1024	Enoyl-CoA hydratase
EYC57_RS08270	COG0494	nUDIX hydrolase
EYC57_RS08315	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYC57_RS08315	COG0116	Belongs to the methyltransferase superfamily
EYC57_RS08345	COG0667	Aldo Keto reductase
EYC57_RS08355	COG2925	Exonuclease
EYC57_RS08365	COG3844	kynureninase activity
EYC57_RS08380	COG0288	reversible hydration of carbon dioxide
EYC57_RS08415	COG0316	Belongs to the HesB IscA family
EYC57_RS08420	COG0360	Binds together with S18 to 16S ribosomal RNA
EYC57_RS08440	COG3115	cell septum assembly
EYC57_RS08450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EYC57_RS08455	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EYC57_RS08470	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EYC57_RS08510	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EYC57_RS08520	COG2986	histidine ammonia-lyase
EYC57_RS08525	COG1228	amidohydrolase
EYC57_RS08570	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EYC57_RS08575	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EYC57_RS08580	COG0077	Prephenate dehydratase
EYC57_RS08580	COG1605	Chorismate mutase
EYC57_RS08585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EYC57_RS08605	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EYC57_RS08620	COG0583	DNA-binding transcription factor activity
EYC57_RS08675	COG3039	Transposase
EYC57_RS08725	COG0840	transmembrane signaling receptor activity
EYC57_RS08740	COG0784	Response regulator, receiver
EYC57_RS08740	COG4191	Histidine kinase
EYC57_RS08745	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EYC57_RS08750	COG4191	Histidine kinase
EYC57_RS08750	COG0784	Response regulator, receiver
EYC57_RS08765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC57_RS08785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYC57_RS08850	COG2244	polysaccharide biosynthetic process
EYC57_RS08880	COG2264	protein methyltransferase activity
EYC57_RS08890	COG0438	transferase activity, transferring glycosyl groups
EYC57_RS08905	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EYC57_RS08910	COG1132	(ABC) transporter
EYC57_RS08920	COG2271	Major facilitator Superfamily
EYC57_RS08940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYC57_RS08955	COG1253	flavin adenine dinucleotide binding
EYC57_RS09000	COG0504	CTP synthase activity
EYC57_RS09005	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EYC57_RS09015	COG0148	phosphopyruvate hydratase activity
EYC57_RS09020	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EYC57_RS09035	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EYC57_RS09045	COG2840	Smr protein MutS2
EYC57_RS09050	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EYC57_RS09055	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EYC57_RS09060	COG1238	metal cluster binding
EYC57_RS09075	COG1534	Rna-binding protein
EYC57_RS09080	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EYC57_RS09090	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EYC57_RS09105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EYC57_RS09110	COG1546	Belongs to the CinA family
EYC57_RS09125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EYC57_RS09135	COG2137	regulation of response to DNA damage stimulus
EYC57_RS09140	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EYC57_RS09145	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EYC57_RS09175	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EYC57_RS09205	COG1741	Belongs to the pirin family
EYC57_RS09210	COG0583	DNA-binding transcription factor activity
EYC57_RS09235	COG0352	thiamine-phosphate diphosphorylase activity
EYC57_RS09235	COG0351	phosphomethylpyrimidine kinase
EYC57_RS09245	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EYC57_RS09250	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYC57_RS09265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYC57_RS09275	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EYC57_RS09280	COG3734	2-keto-3-deoxy-galactonokinase
EYC57_RS09290	COG4948	Mandelate Racemase Muconate Lactonizing
EYC57_RS09295	COG0800	Aldolase
EYC57_RS09320	COG1070	Carbohydrate kinase
EYC57_RS09330	COG0477	Major facilitator Superfamily
EYC57_RS09360	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYC57_RS09365	COG1469	GTP cyclohydrolase I activity
EYC57_RS09375	COG0617	tRNA 3'-terminal CCA addition
EYC57_RS09395	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EYC57_RS09425	COG1472	Belongs to the glycosyl hydrolase 3 family
EYC57_RS09445	COG2203	Gaf domain
EYC57_RS09445	COG3706	GGDEF domain
EYC57_RS09445	COG4251	negative regulation of phosphorylation
EYC57_RS09445	COG5001	Diguanylate cyclase
EYC57_RS09455	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYC57_RS09465	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EYC57_RS09480	COG0671	phosphoesterase, PA-phosphatase related
EYC57_RS09500	COG1794	racemase activity, acting on amino acids and derivatives
EYC57_RS09510	COG0697	spore germination
EYC57_RS09515	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EYC57_RS09535	COG1012	belongs to the aldehyde dehydrogenase family
EYC57_RS09570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EYC57_RS09590	COG0124	histidyl-tRNA synthetase
EYC57_RS09605	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EYC57_RS09620	COG0131	Imidazoleglycerol-phosphate dehydratase
EYC57_RS09620	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EYC57_RS09630	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EYC57_RS09640	COG0140	phosphoribosyl-ATP diphosphatase activity
EYC57_RS09640	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EYC57_RS09660	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EYC57_RS09665	COG0235	Class ii aldolase
EYC57_RS09670	COG0531	amino acid
EYC57_RS09675	COG0531	amino acid
EYC57_RS09685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYC57_RS09690	COG0277	FAD linked oxidase domain protein
EYC57_RS09715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EYC57_RS09765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYC57_RS09770	COG2258	MOSC domain
EYC57_RS09775	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EYC57_RS09780	COG0505	Belongs to the CarA family
EYC57_RS09790	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYC57_RS09795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYC57_RS09805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EYC57_RS09820	COG3279	Response regulator of the LytR AlgR family
EYC57_RS09845	COG0784	Response regulator, receiver
EYC57_RS09845	COG2198	Histidine kinase
EYC57_RS09845	COG2205	protein histidine kinase activity
EYC57_RS09850	COG1024	Enoyl-CoA hydratase
EYC57_RS09855	COG0318	PFAM AMP-dependent synthetase and ligase
EYC57_RS09860	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS09890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYC57_RS09925	COG0840	transmembrane signaling receptor activity
EYC57_RS09935	COG0835	chemotaxis
EYC57_RS09960	COG0840	transmembrane signaling receptor activity
EYC57_RS09965	COG0840	transmembrane signaling receptor activity
EYC57_RS09970	COG0840	transmembrane signaling receptor activity
EYC57_RS09975	COG0840	transmembrane signaling receptor activity
EYC57_RS09980	COG0840	transmembrane signaling receptor activity
EYC57_RS09990	COG0840	transmembrane signaling receptor activity
EYC57_RS09995	COG0840	transmembrane signaling receptor activity
EYC57_RS10000	COG0840	transmembrane signaling receptor activity
EYC57_RS10015	COG0840	transmembrane signaling receptor activity
EYC57_RS10040	COG0840	transmembrane signaling receptor activity
EYC57_RS10050	COG0745	RESPONSE REGULATOR receiver
EYC57_RS10060	COG0835	chemotaxis
EYC57_RS10065	COG1192	Involved in chromosome partitioning
EYC57_RS10070	COG1360	Flagellar Motor Protein
EYC57_RS10075	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EYC57_RS10085	COG4774	siderophore transport
EYC57_RS10090	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYC57_RS10210	COG0800	Aldolase
EYC57_RS10215	COG0129	dihydroxy-acid dehydratase activity
EYC57_RS10220	COG0363	glucosamine-6-phosphate deaminase activity
EYC57_RS10230	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EYC57_RS10245	COG0354	folic acid binding
EYC57_RS10260	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EYC57_RS10275	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EYC57_RS10290	COG4591	ABC-type transport system involved in lipoprotein release permease component
EYC57_RS10315	COG0811	peptide transport
EYC57_RS10330	COG1663	tetraacyldisaccharide 4'-kinase activity
EYC57_RS10340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYC57_RS10350	COG0322	excinuclease ABC activity
EYC57_RS10385	COG0037	tRNA processing
EYC57_RS10400	COG2234	aminopeptidase activity
EYC57_RS10405	COG2814	Major facilitator Superfamily
EYC57_RS10425	COG3039	Transposase
EYC57_RS10455	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EYC57_RS10475	COG1054	Belongs to the UPF0176 family
EYC57_RS10490	COG1530	ribonuclease E activity
EYC57_RS10500	COG3064	Membrane
EYC57_RS10520	COG2154	pterin-4-alpha-carbinolamine dehydratase
EYC57_RS10535	COG3039	Transposase
EYC57_RS10555	COG4302	ethanolamine ammonia-lyase activity
EYC57_RS10565	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EYC57_RS10590	COG2166	iron-sulfur cluster assembly
EYC57_RS10605	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EYC57_RS10610	COG0137	argininosuccinate synthase activity
EYC57_RS10615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYC57_RS10620	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYC57_RS10635	COG0165	Argininosuccinate lyase
EYC57_RS10690	COG1271	oxidase subunit
EYC57_RS10700	COG4988	ABC transporter
EYC57_RS10705	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EYC57_RS10715	COG1278	Cold shock
EYC57_RS10765	COG4133	protoheme IX ABC transporter activity
EYC57_RS10770	COG0436	Aminotransferase
EYC57_RS10790	COG1187	pseudouridine synthase activity
EYC57_RS10795	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EYC57_RS10800	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EYC57_RS10805	COG2350	Protein conserved in bacteria
EYC57_RS10835	COG1175	transmembrane transport
EYC57_RS10840	COG0395	ABC-type sugar transport system, permease component
EYC57_RS10865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYC57_RS10875	COG2957	Belongs to the agmatine deiminase family
EYC57_RS10890	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EYC57_RS10895	COG0539	negative regulation of cytoplasmic translation
EYC57_RS10900	COG0776	regulation of translation
EYC57_RS10910	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EYC57_RS10915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYC57_RS10925	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EYC57_RS10940	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EYC57_RS10950	COG0519	Catalyzes the synthesis of GMP from XMP
EYC57_RS10950	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYC57_RS10955	COG3002	Belongs to the UPF0753 family
EYC57_RS10960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYC57_RS10965	COG0583	DNA-binding transcription factor activity
EYC57_RS10995	COG0583	DNA-binding transcription factor activity
EYC57_RS11020	COG1914	H( )-stimulated, divalent metal cation uptake system
EYC57_RS11040	COG0668	transmembrane transport
EYC57_RS11050	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EYC57_RS11065	COG1028	Short-chain dehydrogenase reductase Sdr
EYC57_RS11070	COG1183	phosphatidylcholine synthase activity
EYC57_RS11080	COG3243	poly(R)-hydroxyalkanoic acid synthase
EYC57_RS11095	COG0723	plastoquinol--plastocyanin reductase activity
EYC57_RS11095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC57_RS11105	COG2183	response to ionizing radiation
EYC57_RS11120	COG2205	protein histidine kinase activity
EYC57_RS11120	COG0784	Response regulator, receiver
EYC57_RS11210	COG2198	Histidine kinase
EYC57_RS11210	COG0643	Histidine kinase
EYC57_RS11210	COG0784	Response regulator, receiver
EYC57_RS11265	COG1684	flagellar biosynthetic protein fliR
EYC57_RS11280	COG3190	flagellar
EYC57_RS11330	COG1677	Flagellar hook-basal body complex protein FliE
EYC57_RS11350	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS11395	COG1028	Short-chain dehydrogenase reductase Sdr
EYC57_RS11405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYC57_RS11425	COG2201	protein-glutamate methylesterase activity
EYC57_RS11455	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EYC57_RS11460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EYC57_RS11475	COG1705	Flagellar rod assembly protein muramidase FlgJ
EYC57_RS11475	COG3951	Flagellar rod assembly protein muramidase FlgJ
EYC57_RS11480	COG1706	bacterial-type flagellum-dependent cell motility
EYC57_RS11485	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EYC57_RS11500	COG4787	bacterial-type flagellum-dependent cell motility
EYC57_RS11510	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EYC57_RS11515	COG1558	bacterial-type flagellum-dependent cell motility
EYC57_RS11525	COG0784	Response regulator, receiver
EYC57_RS11525	COG0835	chemotaxis
EYC57_RS11545	COG5002	protein histidine kinase activity
EYC57_RS11555	COG4585	Histidine kinase
EYC57_RS11585	COG0482	sulfurtransferase activity
EYC57_RS11600	COG0542	response to heat
EYC57_RS11625	COG0492	ferredoxin-NADP+ reductase activity
EYC57_RS11630	COG1674	ftsk spoiiie
EYC57_RS11655	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EYC57_RS11675	COG0038	chloride channel
EYC57_RS11680	COG0183	Belongs to the thiolase family
EYC57_RS11685	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYC57_RS11685	COG1024	Enoyl-CoA hydratase
EYC57_RS11700	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EYC57_RS11720	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC57_RS11725	COG1160	GTP binding
EYC57_RS11730	COG0303	'Molybdopterin
EYC57_RS11740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EYC57_RS11755	COG0708	Exodeoxyribonuclease III
EYC57_RS11770	COG0746	molybdenum cofactor guanylyltransferase activity
EYC57_RS11795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYC57_RS11795	COG1648	precorrin-2 dehydrogenase activity
EYC57_RS11830	COG3685	Protein conserved in bacteria
EYC57_RS11850	COG5001	Diguanylate cyclase
EYC57_RS11860	COG4566	intracellular signal transduction
EYC57_RS11920	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS12050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC57_RS12055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC57_RS12100	COG1858	cytochrome C peroxidase
EYC57_RS12130	COG0515	serine threonine protein kinase
EYC57_RS12135	COG0631	protein serine/threonine phosphatase activity
EYC57_RS12235	COG3039	Transposase
EYC57_RS12240	COG3039	Transposase
EYC57_RS12245	COG3039	Transposase
EYC57_RS12265	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS12280	COG4677	pectinesterase activity
EYC57_RS12310	COG0402	S-adenosylhomocysteine deaminase activity
EYC57_RS12325	COG1509	lysine 2,3-aminomutase activity
EYC57_RS12330	COG5001	Diguanylate cyclase
EYC57_RS12330	COG3300	MHYT domain
EYC57_RS12345	COG0483	inositol monophosphate 1-phosphatase activity
EYC57_RS12350	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYC57_RS12375	COG0488	(ABC) transporter
EYC57_RS12380	COG0513	Belongs to the DEAD box helicase family
EYC57_RS12390	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EYC57_RS12400	COG0625	glutathione transferase activity
EYC57_RS12410	COG1671	Belongs to the UPF0178 family
EYC57_RS12415	COG4681	YaeQ
EYC57_RS12420	COG2081	HI0933 family
EYC57_RS12430	COG0501	Belongs to the peptidase M48B family
EYC57_RS12440	COG1028	Short-chain dehydrogenase reductase Sdr
EYC57_RS12465	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EYC57_RS12470	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYC57_RS12475	COG0802	atpase or kinase
EYC57_RS12480	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EYC57_RS12480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYC57_RS12485	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYC57_RS12505	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYC57_RS12575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EYC57_RS12670	COG2801	Transposase and inactivated derivatives
EYC57_RS12680	COG0835	chemotaxis
EYC57_RS12685	COG0840	transmembrane signaling receptor activity
EYC57_RS12715	COG2969	positive regulation of protein catabolic process
EYC57_RS12720	COG0625	glutathione transferase activity
EYC57_RS12725	COG2857	Cytochrome c1
EYC57_RS12730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EYC57_RS12735	COG0723	plastoquinol--plastocyanin reductase activity
EYC57_RS12740	COG0741	lytic transglycosylase activity
EYC57_RS12760	COG1702	phosphate starvation-inducible protein PhoH
EYC57_RS12780	COG4535	Mg2 and Co2 transporter CorC
EYC57_RS12795	COG1012	belongs to the aldehyde dehydrogenase family
EYC57_RS12805	COG1177	transmembrane transport
EYC57_RS12810	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYC57_RS12820	COG3842	ATPase activity
EYC57_RS12840	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EYC57_RS12865	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EYC57_RS12870	COG0174	glutamine synthetase
EYC57_RS12875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC57_RS12885	COG0477	Major facilitator Superfamily
EYC57_RS12895	COG0243	molybdopterin cofactor binding
EYC57_RS12905	COG2223	nitrite transmembrane transporter activity
EYC57_RS12915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EYC57_RS12920	COG1121	(ABC) transporter
EYC57_RS12930	COG2733	membrane
EYC57_RS12950	COG0477	Major facilitator Superfamily
EYC57_RS12965	COG2902	Dehydrogenase
EYC57_RS12975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC57_RS12980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC57_RS13000	COG1609	Transcriptional regulator
EYC57_RS13005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYC57_RS13005	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYC57_RS13010	COG1105	Belongs to the carbohydrate kinase PfkB family
EYC57_RS13015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYC57_RS13015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYC57_RS13045	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS13095	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYC57_RS13105	COG1862	Preprotein translocase
EYC57_RS13110	COG0343	queuine tRNA-ribosyltransferase activity
EYC57_RS13165	COG0405	Gamma-glutamyltransferase
EYC57_RS13170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EYC57_RS13185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EYC57_RS13190	COG0742	ribosomal rna small subunit methyltransferase
EYC57_RS13195	COG0326	Molecular chaperone. Has ATPase activity
EYC57_RS13260	COG4206	TonB-dependent receptor
EYC57_RS13310	COG0531	amino acid
EYC57_RS13325	COG0006	proline dipeptidase activity
EYC57_RS13335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYC57_RS13350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC57_RS13355	COG3938	Belongs to the proline racemase family
EYC57_RS13365	COG0552	protein localization to endoplasmic reticulum
EYC57_RS13380	COG1194	a g-specific adenine glycosylase
EYC57_RS13390	COG0784	Response regulator, receiver
EYC57_RS13390	COG4191	Histidine kinase
EYC57_RS13395	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EYC57_RS13415	COG3040	lipid binding
EYC57_RS13425	COG1960	acyl-CoA dehydrogenase activity
EYC57_RS13435	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EYC57_RS13465	COG0438	transferase activity, transferring glycosyl groups
EYC57_RS13475	COG0438	transferase activity, transferring glycosyl groups
EYC57_RS13480	COG0438	transferase activity, transferring glycosyl groups
EYC57_RS13535	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EYC57_RS13550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EYC57_RS13585	COG0556	nucleotide-excision repair
EYC57_RS13590	COG4969	Belongs to the N-Me-Phe pilin family
EYC57_RS13630	COG1611	Belongs to the LOG family
EYC57_RS13645	COG2095	MarC family integral membrane protein
EYC57_RS13655	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EYC57_RS13690	COG1185	polyribonucleotide nucleotidyltransferase activity
EYC57_RS13695	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EYC57_RS13710	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EYC57_RS13715	COG0195	Participates in both transcription termination and antitermination
EYC57_RS13720	COG0779	Required for maturation of 30S ribosomal subunits
EYC57_RS13730	COG1007	ATP synthesis coupled electron transport
EYC57_RS13760	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EYC57_RS13765	COG1034	ATP synthesis coupled electron transport
EYC57_RS13770	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EYC57_RS13775	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EYC57_RS13780	COG0649	NAD binding
EYC57_RS13785	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYC57_RS13795	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYC57_RS13810	COG0149	triose-phosphate isomerase activity
EYC57_RS13850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYC57_RS13855	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EYC57_RS13870	COG0133	tryptophan synthase activity
EYC57_RS13880	COG0135	phosphoribosylanthranilate isomerase activity
EYC57_RS13885	COG0101	tRNA pseudouridine synthase activity
EYC57_RS13905	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EYC57_RS13910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYC57_RS13915	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EYC57_RS13920	COG2890	protein-(glutamine-N5) methyltransferase activity
EYC57_RS13950	COG0433	COG0433 Predicted ATPase
EYC57_RS13980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYC57_RS14000	COG3039	Transposase
EYC57_RS14055	COG0386	Belongs to the glutathione peroxidase family
EYC57_RS14065	COG0339	signal peptide processing
EYC57_RS14160	COG2814	Major facilitator Superfamily
EYC57_RS14165	COG1566	PFAM secretion protein HlyD family protein
EYC57_RS14215	COG4774	siderophore transport
EYC57_RS14225	COG0367	asparagine synthase
EYC57_RS14230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYC57_RS14240	COG1393	Belongs to the ArsC family
EYC57_RS14300	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EYC57_RS14315	COG0233	cytoplasmic translational termination
EYC57_RS14325	COG0575	Belongs to the CDS family
EYC57_RS14330	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EYC57_RS14335	COG0750	zinc metalloprotease
EYC57_RS14350	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYC57_RS14355	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYC57_RS14360	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYC57_RS14380	COG0825	malonyl-CoA metabolic process
EYC57_RS14405	COG1981	membrane
EYC57_RS14450	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EYC57_RS14465	COG2040	homocysteine
EYC57_RS14470	COG0833	amino acid
EYC57_RS14475	COG0346	lactoylglutathione lyase activity
EYC57_RS14485	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYC57_RS14485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYC57_RS14495	COG2878	Part of a membrane complex involved in electron transport
EYC57_RS14515	COG1595	DNA-templated transcription, initiation
EYC57_RS14540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYC57_RS14555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYC57_RS14560	COG0251	oxidation-reduction process
EYC57_RS14575	COG0392	lysyltransferase activity
EYC57_RS14575	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EYC57_RS14620	COG2814	Major facilitator Superfamily
EYC57_RS14625	COG1902	pentaerythritol trinitrate reductase activity
EYC57_RS14645	COG2824	Alkylphosphonate utilization operon protein PhnA
EYC57_RS14655	COG1047	Peptidyl-prolyl cis-trans
EYC57_RS14695	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EYC57_RS14710	COG1451	nucleotide metabolic process
EYC57_RS14730	COG0183	Belongs to the thiolase family
EYC57_RS14760	COG1793	dna ligase
EYC57_RS14760	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EYC57_RS14770	COG1793	dna ligase
EYC57_RS14775	COG1201	RNA secondary structure unwinding
EYC57_RS14790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC57_RS14795	COG1278	Cold shock
EYC57_RS14800	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EYC57_RS14805	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EYC57_RS14815	COG3046	protein related to deoxyribodipyrimidine photolyase
EYC57_RS14820	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EYC57_RS14825	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EYC57_RS14830	COG2954	triphosphatase activity
EYC57_RS14845	COG1381	Involved in DNA repair and RecF pathway recombination
EYC57_RS14875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYC57_RS14890	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYC57_RS14890	COG1024	Enoyl-CoA hydratase
EYC57_RS14915	COG1960	acyl-CoA dehydrogenase activity
EYC57_RS14980	COG5002	protein histidine kinase activity
EYC57_RS14980	COG0784	Response regulator, receiver
EYC57_RS14985	COG2205	protein histidine kinase activity
EYC57_RS14985	COG0784	Response regulator, receiver
EYC57_RS14985	COG2198	Histidine kinase
EYC57_RS14990	COG2353	YceI-like domain
EYC57_RS15015	COG1760	l-serine dehydratase
EYC57_RS15020	COG0527	aspartate kinase activity
EYC57_RS15020	COG0460	homoserine dehydrogenase
EYC57_RS15025	COG0626	cystathionine gamma-synthase activity
EYC57_RS15030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYC57_RS15035	COG0739	heme binding
EYC57_RS15045	COG1272	protein, Hemolysin III
EYC57_RS15055	COG0516	GMP reductase activity
EYC57_RS15055	COG0517	IMP dehydrogenase activity
EYC57_RS15060	COG0463	Glycosyl transferase, family 2
EYC57_RS15070	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EYC57_RS15080	COG4771	TonB-dependent receptor
EYC57_RS15085	COG1309	transcriptional regulator
EYC57_RS15095	COG1960	acyl-CoA dehydrogenase activity
EYC57_RS15125	COG0509	glycine decarboxylation via glycine cleavage system
EYC57_RS15140	COG0330	HflC and HflK could
EYC57_RS15150	COG1742	UPF0060 membrane protein
EYC57_RS15155	COG3956	TIGRFAM MazG family protein
EYC57_RS15170	COG0494	nUDIX hydrolase
EYC57_RS15180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EYC57_RS15185	COG0837	glucose binding
EYC57_RS15200	COG1388	LysM domain
EYC57_RS15200	COG3858	chitin binding
EYC57_RS15220	COG1472	Belongs to the glycosyl hydrolase 3 family
EYC57_RS15265	COG3537	Alpha-1,2-mannosidase
EYC57_RS15315	COG3142	Participates in the control of copper homeostasis
EYC57_RS15320	COG1446	asparaginase
EYC57_RS15355	COG0643	Histidine kinase
EYC57_RS15355	COG0784	Response regulator, receiver
EYC57_RS15355	COG2198	Histidine kinase
EYC57_RS15360	COG0840	transmembrane signaling receptor activity
EYC57_RS15365	COG0835	chemotaxis
EYC57_RS15380	COG0189	ligase activity
EYC57_RS15400	COG1199	ATP-dependent helicase activity
EYC57_RS15410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYC57_RS15415	COG1215	transferase activity, transferring glycosyl groups
EYC57_RS15425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYC57_RS15475	COG1643	Atp-dependent helicase
EYC57_RS15480	COG0783	Belongs to the Dps family
EYC57_RS15490	COG0514	ATP-dependent DNA helicase (RecQ)
EYC57_RS15510	COG1187	pseudouridine synthase activity
EYC57_RS15550	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EYC57_RS15560	COG0602	queuosine metabolic process
EYC57_RS15570	COG2885	chlorophyll binding
EYC57_RS15575	COG0823	Involved in the tonB-independent uptake of proteins
EYC57_RS15595	COG0824	Thioesterase
EYC57_RS15600	COG2255	four-way junction helicase activity
EYC57_RS15615	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EYC57_RS15620	COG0217	transcriptional regulatory protein
EYC57_RS15635	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EYC57_RS15650	COG0477	Major facilitator Superfamily
EYC57_RS15665	COG2755	lipolytic protein G-D-S-L family
EYC57_RS15665	COG0657	acetylesterase activity
EYC57_RS15685	COG0488	(ABC) transporter
EYC57_RS15715	COG4651	solute:proton antiporter activity
EYC57_RS15715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EYC57_RS15730	COG4772	TonB-dependent receptor
EYC57_RS15740	COG4264	IucA IucC family
EYC57_RS15755	COG0019	diaminopimelate decarboxylase activity
EYC57_RS15775	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EYC57_RS15810	COG4206	TonB-dependent receptor
EYC57_RS15825	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
EYC57_RS15830	COG0631	protein serine/threonine phosphatase activity
EYC57_RS15835	COG4245	von Willebrand factor, type A
EYC57_RS15855	COG0542	response to heat
EYC57_RS15880	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EYC57_RS15890	COG0534	Mate efflux family protein
EYC57_RS15905	COG0336	Belongs to the RNA methyltransferase TrmD family
EYC57_RS15910	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EYC57_RS15915	COG0228	four-way junction DNA binding
EYC57_RS16105	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EYC57_RS16130	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EYC57_RS16145	COG2197	response regulator
EYC57_RS16150	COG4585	Histidine kinase
EYC57_RS16165	COG2894	cell division
EYC57_RS16170	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EYC57_RS16180	COG0642	Histidine kinase
EYC57_RS16185	COG0745	RESPONSE REGULATOR receiver
EYC57_RS16190	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EYC57_RS16200	COG2194	sulfuric ester hydrolase activity
EYC57_RS16230	COG3551	Protein conserved in bacteria
EYC57_RS16240	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EYC57_RS16240	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EYC57_RS16270	COG0753	catalase activity
EYC57_RS16310	COG2207	Transcriptional regulator
EYC57_RS16310	COG1917	Cupin 2, conserved barrel domain protein
EYC57_RS16320	COG1506	peptidase
EYC57_RS16320	COG0823	Involved in the tonB-independent uptake of proteins
EYC57_RS16340	COG1297	OPT oligopeptide transporter protein
EYC57_RS16360	COG0587	DNA-directed DNA polymerase activity
EYC57_RS16450	COG0732	type I restriction modification DNA specificity domain
EYC57_RS16485	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EYC57_RS16545	COG0308	aminopeptidase N
EYC57_RS16550	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EYC57_RS16560	COG0330	HflC and HflK could
EYC57_RS16565	COG0330	HflC and HflK could
EYC57_RS16635	COG3039	Transposase
EYC57_RS16660	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EYC57_RS16675	COG3829	transcription factor binding
EYC57_RS16710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EYC57_RS16715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EYC57_RS16725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYC57_RS16730	COG1028	Short-chain dehydrogenase reductase Sdr
EYC57_RS16755	COG1399	metal-binding, possibly nucleic acid-binding protein
EYC57_RS16775	COG0714	Associated with various cellular activities
EYC57_RS16795	COG0537	adenosine 5'-monophosphoramidase activity
EYC57_RS16805	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EYC57_RS16825	COG0314	molybdopterin synthase activity
EYC57_RS16830	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EYC57_RS16835	COG0315	cyclic pyranopterin monophosphate synthase activity
EYC57_RS16845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EYC57_RS16850	COG1234	tRNA 3'-trailer cleavage
EYC57_RS16855	COG3642	lipopolysaccharide core region biosynthetic process
EYC57_RS16860	COG0859	PFAM glycosyl transferase family 9
EYC57_RS16875	COG0631	protein serine/threonine phosphatase activity
EYC57_RS16880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EYC57_RS16910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYC57_RS16950	COG0544	peptidyl-prolyl cis-trans isomerase activity
EYC57_RS17005	COG0473	3-isopropylmalate dehydrogenase activity
EYC57_RS17020	COG4783	chaperone-mediated protein folding
EYC57_RS17035	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EYC57_RS17050	COG0671	phosphoesterase, PA-phosphatase related
EYC57_RS17055	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYC57_RS17065	COG3291	Pkd domain containing protein
EYC57_RS17075	COG2833	Protein of unknown function (DUF455)
EYC57_RS17095	COG0285	dihydrofolate synthase activity
EYC57_RS17105	COG0406	alpha-ribazole phosphatase activity
EYC57_RS17140	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EYC57_RS17145	COG4208	sulfate ABC transporter
EYC57_RS17150	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EYC57_RS17155	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EYC57_RS17160	COG0156	8-amino-7-oxononanoate synthase activity
EYC57_RS17195	COG1902	pentaerythritol trinitrate reductase activity
EYC57_RS17195	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYC57_RS17215	COG0584	glycerophosphoryl diester phosphodiesterase
EYC57_RS17225	COG0625	glutathione transferase activity
EYC57_RS17235	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EYC57_RS17240	COG1217	gtp-binding protein TYPA
EYC57_RS17260	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EYC57_RS17270	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EYC57_RS17275	COG0203	ribosomal protein L17
EYC57_RS17285	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EYC57_RS17300	COG0201	protein transport
EYC57_RS17305	COG0200	Binds to the 23S rRNA
EYC57_RS17310	COG1841	ribosomal large subunit assembly
EYC57_RS17320	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EYC57_RS17345	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EYC57_RS17350	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EYC57_RS17355	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EYC57_RS17360	COG0255	Belongs to the universal ribosomal protein uL29 family
EYC57_RS17365	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EYC57_RS17375	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EYC57_RS17385	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EYC57_RS17390	COG0089	rRNA binding
EYC57_RS17395	COG0088	Forms part of the polypeptide exit tunnel
EYC57_RS17405	COG0051	transcription antitermination factor activity, RNA binding
EYC57_RS17425	COG0049	tRNA binding
EYC57_RS17430	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EYC57_RS17435	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EYC57_RS17440	COG0085	RNA polymerase activity
EYC57_RS17445	COG0222	ribosome binding
EYC57_RS17450	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EYC57_RS17455	COG0081	regulation of translation
EYC57_RS17460	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EYC57_RS17470	COG0250	Participates in transcription elongation, termination and antitermination
EYC57_RS17475	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EYC57_RS17505	COG0012	GTP binding
EYC57_RS17510	COG0193	aminoacyl-tRNA hydrolase activity
EYC57_RS17520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYC57_RS17535	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EYC57_RS17545	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EYC57_RS17550	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EYC57_RS17560	COG0521	Mo-molybdopterin cofactor biosynthetic process
EYC57_RS17580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC57_RS17585	COG1295	ribonuclease BN
EYC57_RS17615	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EYC57_RS17625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYC57_RS17675	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EYC57_RS17725	COG2890	protein-(glutamine-N5) methyltransferase activity
EYC57_RS17735	COG3634	alkyl hydroperoxide reductase activity
EYC57_RS17740	COG0583	DNA-binding transcription factor activity
EYC57_RS17750	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EYC57_RS17755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYC57_RS17765	COG2197	response regulator
EYC57_RS17805	COG0697	spore germination
EYC57_RS17835	COG3386	PFAM SMP-30 Gluconolaconase
EYC57_RS17855	COG1024	Enoyl-CoA hydratase
EYC57_RS17870	COG0583	DNA-binding transcription factor activity
EYC57_RS17875	COG3384	dioxygenase
EYC57_RS17885	COG1802	Transcriptional regulator
EYC57_RS17905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC57_RS17910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC57_RS17920	COG2096	Adenosyltransferase
EYC57_RS17925	COG0123	including yeast histone deacetylase and acetoin utilization protein
EYC57_RS17940	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EYC57_RS17950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EYC57_RS17955	COG2967	ApaG domain
EYC57_RS17960	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EYC57_RS17980	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EYC57_RS18000	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EYC57_RS18015	COG0642	Histidine kinase
EYC57_RS18030	COG4181	ATPase activity
EYC57_RS18040	COG2175	clavaminate synthase activity
EYC57_RS18050	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EYC57_RS18055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYC57_RS18075	COG0667	Aldo Keto reductase
EYC57_RS18085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EYC57_RS18090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYC57_RS18100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYC57_RS18115	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EYC57_RS18140	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS18160	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS18195	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EYC57_RS18200	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EYC57_RS18260	COG3321	synthase
EYC57_RS18260	COG0604	alcohol dehydrogenase
EYC57_RS18260	COG1028	Short-chain dehydrogenase reductase Sdr
EYC57_RS18275	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EYC57_RS18290	COG0494	nUDIX hydrolase
EYC57_RS18305	COG4942	peptidase
EYC57_RS18305	COG1388	LysM domain
EYC57_RS18315	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EYC57_RS18330	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EYC57_RS18335	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYC57_RS18340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYC57_RS18355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYC57_RS18360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EYC57_RS18375	COG3116	cell division
EYC57_RS18380	COG0275	rRNA processing
EYC57_RS18410	COG0792	nuclease activity
EYC57_RS18415	COG1988	membrane-bound metal-dependent
EYC57_RS18420	COG0277	FAD linked oxidase domain protein
EYC57_RS18425	COG0745	RESPONSE REGULATOR receiver
EYC57_RS18430	COG2205	protein histidine kinase activity
EYC57_RS18440	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EYC57_RS18445	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EYC57_RS18470	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EYC57_RS18475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYC57_RS18480	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EYC57_RS18500	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYC57_RS18500	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYC57_RS18510	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EYC57_RS18520	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EYC57_RS18540	COG0488	(ABC) transporter
EYC57_RS18590	COG2205	protein histidine kinase activity
EYC57_RS18605	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EYC57_RS18635	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS18675	COG0726	polysaccharide deacetylase
EYC57_RS18675	COG1649	PFAM Uncharacterised BCR, COG1649
EYC57_RS18680	COG1215	transferase activity, transferring glycosyl groups
EYC57_RS18690	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EYC57_RS18695	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYC57_RS18700	COG1609	Transcriptional regulator
EYC57_RS18710	COG2188	Transcriptional regulator
EYC57_RS18725	COG3250	beta-galactosidase activity
EYC57_RS18765	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EYC57_RS18770	COG4191	Histidine kinase
EYC57_RS18775	COG0784	Response regulator, receiver
EYC57_RS18780	COG4251	negative regulation of phosphorylation
EYC57_RS18785	COG2823	Periplasmic or secreted lipoprotein
EYC57_RS18790	COG0673	inositol 2-dehydrogenase activity
EYC57_RS18795	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EYC57_RS18830	COG1056	cytidyltransferase-related domain
EYC57_RS18830	COG1051	belongs to the nudix hydrolase family
EYC57_RS18855	COG2921	Belongs to the UPF0250 family
EYC57_RS18870	COG1686	Belongs to the peptidase S11 family
EYC57_RS18875	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EYC57_RS18880	COG2951	lytic endotransglycosylase activity
EYC57_RS18925	COG0772	Belongs to the SEDS family
EYC57_RS18940	COG1792	Involved in formation and maintenance of cell shape
EYC57_RS18945	COG1077	Cell shape determining protein MreB Mrl
EYC57_RS18950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYC57_RS18965	COG0308	aminopeptidase N
EYC57_RS18970	COG3300	MHYT domain
EYC57_RS18970	COG5001	Diguanylate cyclase
EYC57_RS19005	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EYC57_RS19015	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EYC57_RS19035	COG2832	Protein of unknown function (DUF454)
EYC57_RS19045	COG0436	Aminotransferase
EYC57_RS19055	COG1505	serine-type exopeptidase activity
EYC57_RS19080	COG0181	hydroxymethylbilane synthase activity
EYC57_RS19090	COG3275	phosphorelay sensor kinase activity
EYC57_RS19125	COG0659	secondary active sulfate transmembrane transporter activity
EYC57_RS19130	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYC57_RS19130	COG5297	Belongs to the glycosyl hydrolase family 6
EYC57_RS19140	COG0840	transmembrane signaling receptor activity
EYC57_RS19205	COG0598	Magnesium transport protein CorA
EYC57_RS19215	COG1113	amino acid transport
EYC57_RS19225	COG5297	Belongs to the glycosyl hydrolase family 6
EYC57_RS19230	COG4305	rare lipoprotein A
EYC57_RS19235	COG0697	spore germination
EYC57_RS19285	COG4221	oxidoreductase activity
EYC57_RS19360	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EYC57_RS19390	COG2353	YceI-like domain
EYC57_RS19420	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EYC57_RS19450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EYC57_RS19455	COG3550	peptidyl-serine autophosphorylation
EYC57_RS19470	COG0459	protein refolding
EYC57_RS19495	COG1252	NADH dehydrogenase
EYC57_RS19500	COG2860	membrane
EYC57_RS19505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYC57_RS19510	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EYC57_RS19515	COG3437	response regulator, receiver
EYC57_RS19520	COG2177	Part of the ABC transporter FtsEX involved in
EYC57_RS19525	COG2884	Cell division ATP-binding protein ftsE
EYC57_RS19535	COG3118	belongs to the thioredoxin family
EYC57_RS19540	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EYC57_RS19580	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EYC57_RS19580	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EYC57_RS19625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYC57_RS19635	COG1560	Kdo2-lipid A biosynthetic process
EYC57_RS19685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYC57_RS19685	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EYC57_RS19690	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EYC57_RS19695	COG0242	peptide deformylase activity
EYC57_RS19700	COG1652	LysM domain
EYC57_RS19705	COG0758	DNA mediated transformation
EYC57_RS19725	COG1754	DNA topoisomerase type I activity
EYC57_RS19725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYC57_RS19730	COG0009	L-threonylcarbamoyladenylate synthase
EYC57_RS19745	COG1028	Short-chain dehydrogenase reductase Sdr
EYC57_RS19755	COG0616	signal peptide processing
EYC57_RS19760	COG0534	Mate efflux family protein
EYC57_RS19780	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYC57_RS19785	COG1324	tolerance protein
EYC57_RS19805	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EYC57_RS19810	COG0511	ligase activity, forming carbon-carbon bonds
EYC57_RS19820	COG0439	Biotin carboxylase
EYC57_RS19870	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EYC57_RS19905	COG0138	bifunctional purine biosynthesis protein purh
EYC57_RS19910	COG0419	ATPase involved in DNA repair
EYC57_RS19920	COG0151	Belongs to the GarS family
EYC57_RS19935	COG1289	transmembrane transporter activity
EYC57_RS19940	COG2814	Major facilitator Superfamily
EYC57_RS19950	COG2814	Major facilitator Superfamily
EYC57_RS19970	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EYC57_RS20010	COG0745	RESPONSE REGULATOR receiver
EYC57_RS20050	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EYC57_RS20060	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EYC57_RS20070	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EYC57_RS20075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYC57_RS20085	COG0134	indole-3-glycerol-phosphate synthase activity
EYC57_RS20090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYC57_RS20130	COG0456	acetyltransferase
EYC57_RS20140	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EYC57_RS20155	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS20180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYC57_RS20180	COG2111	Na H antiporter
EYC57_RS20185	COG1006	Multisubunit Na H antiporter MnhC subunit
EYC57_RS20190	COG0651	ATP synthesis coupled electron transport
EYC57_RS20200	COG2212	antiporter activity
EYC57_RS20205	COG1320	monovalent cation:proton antiporter activity
EYC57_RS20220	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EYC57_RS20240	COG3104	oligopeptide transport
EYC57_RS20245	COG3483	tryptophan 2,3-dioxygenase activity
EYC57_RS20255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EYC57_RS20270	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYC57_RS20285	COG3039	Transposase
EYC57_RS20290	COG3039	Transposase
EYC57_RS20305	COG0513	Belongs to the DEAD box helicase family
EYC57_RS20335	COG1028	Short-chain dehydrogenase reductase Sdr
EYC57_RS20340	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS20375	COG3039	Transposase
EYC57_RS20380	COG1473	amidohydrolase
EYC57_RS20385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC57_RS20390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC57_RS20415	COG5383	Protein conserved in bacteria
EYC57_RS20465	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EYC57_RS20475	COG3023	N-Acetylmuramoyl-L-alanine amidase
EYC57_RS20485	COG4948	Mandelate Racemase Muconate Lactonizing
EYC57_RS20510	COG0531	amino acid
EYC57_RS20530	COG4682	membrane
EYC57_RS20535	COG2133	pyrroloquinoline quinone binding
EYC57_RS20555	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EYC57_RS20560	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EYC57_RS20570	COG1610	YqeY-like protein
EYC57_RS20590	COG1295	ribonuclease BN
EYC57_RS20595	COG0358	DNA primase activity
EYC57_RS20655	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EYC57_RS20670	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EYC57_RS20725	COG0183	Belongs to the thiolase family
EYC57_RS20770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYC57_RS20775	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EYC57_RS20790	COG0028	Belongs to the TPP enzyme family
EYC57_RS20795	COG4191	Histidine kinase
EYC57_RS20820	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EYC57_RS20835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYC57_RS20840	COG3177	Filamentation induced by cAMP protein fic
EYC57_RS20845	COG0596	Alpha beta hydrolase
EYC57_RS20850	COG0727	PFAM Uncharacterised protein family (UPF0153)
EYC57_RS20855	COG0318	PFAM AMP-dependent synthetase and ligase
EYC57_RS20860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYC57_RS20875	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYC57_RS20890	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EYC57_RS20905	COG0564	pseudouridine synthase activity
EYC57_RS20935	COG0339	signal peptide processing
EYC57_RS20980	COG4770	biotin carboxylase activity
EYC57_RS20985	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYC57_RS20990	COG1960	acyl-CoA dehydrogenase activity
EYC57_RS21040	COG0523	cobalamin synthesis protein
EYC57_RS21055	COG0697	spore germination
EYC57_RS21065	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EYC57_RS21070	COG1846	Transcriptional regulator
EYC57_RS21075	COG1764	response to oxidative stress
EYC57_RS21115	COG1566	PFAM secretion protein HlyD family protein
EYC57_RS21130	COG1199	ATP-dependent helicase activity
EYC57_RS21240	COG0625	glutathione transferase activity
EYC57_RS21275	COG4555	ABC transporter
EYC57_RS21285	COG1476	TRANSCRIPTIONal
EYC57_RS21305	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYC57_RS21310	COG1131	(ABC) transporter
EYC57_RS21315	COG0842	Transport permease protein
EYC57_RS21325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EYC57_RS21370	COG3039	Transposase
EYC57_RS21380	COG2951	lytic endotransglycosylase activity
EYC57_RS21400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYC57_RS21465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYC57_RS21475	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYC57_RS21490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYC57_RS21490	COG1042	CoA-binding domain protein
EYC57_RS21490	COG0045	succinate-CoA ligase (ADP-forming) activity
EYC57_RS21500	COG2239	Acts as a magnesium transporter
EYC57_RS21540	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EYC57_RS21545	COG3387	PFAM Glycoside hydrolase 15-related
EYC57_RS21560	COG3100	YcgL domain-containing protein
EYC57_RS21565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYC57_RS21575	COG0463	Glycosyl transferase, family 2
EYC57_RS21590	COG1028	Short-chain dehydrogenase reductase Sdr
EYC57_RS21625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYC57_RS21640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYC57_RS21685	COG0408	coproporphyrinogen oxidase activity
EYC57_RS21760	COG0210	DNA helicase
EYC57_RS21780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYC57_RS21785	COG0583	DNA-binding transcription factor activity
EYC57_RS21790	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EYC57_RS21805	COG2159	amidohydrolase
EYC57_RS21830	COG0357	Ribosomal RNA small subunit methyltransferase G
EYC57_RS21835	COG3540	Alkaline phosphatase
EYC57_RS21845	COG2091	lysine biosynthetic process via aminoadipic acid
EYC57_RS21860	COG0708	Exodeoxyribonuclease III
EYC57_RS21875	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYC57_RS21880	COG3162	membrane
EYC57_RS21915	COG3507	Belongs to the glycosyl hydrolase 43 family
EYC57_RS21935	COG1028	Short-chain dehydrogenase reductase Sdr
EYC57_RS21940	COG0179	Fumarylacetoacetate (FAA) hydrolase
EYC57_RS21950	COG4948	Mandelate Racemase Muconate Lactonizing
EYC57_RS21955	COG3254	rhamnose metabolic process
EYC57_RS21960	COG0738	Major facilitator superfamily
EYC57_RS21965	COG1414	Transcriptional regulator
EYC57_RS21975	COG2205	protein histidine kinase activity
EYC57_RS21985	COG3459	Glycosyltransferase 36 associated
EYC57_RS21990	COG2211	Major facilitator Superfamily
EYC57_RS21995	COG3265	gluconokinase activity
EYC57_RS22005	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC57_RS22060	COG2911	Protein conserved in bacteria
EYC57_RS22065	COG0729	surface antigen
EYC57_RS22070	COG4771	TonB-dependent receptor
EYC57_RS22075	COG0457	Tetratricopeptide repeat
EYC57_RS22085	COG0752	glycyl-tRNA synthetase alpha subunit
EYC57_RS22090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EYC57_RS22105	COG0519	Catalyzes the synthesis of GMP from XMP
EYC57_RS22105	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYC57_RS22115	COG0805	protein transport
EYC57_RS22120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYC57_RS22125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYC57_RS22135	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EYC57_RS22150	COG3039	Transposase
EYC57_RS22170	COG2974	May be involved in recombination
EYC57_RS22175	COG0037	tRNA processing
EYC57_RS22195	COG3661	Belongs to the glycosyl hydrolase 67 family
EYC57_RS22205	COG4948	Mandelate Racemase Muconate Lactonizing
EYC57_RS22215	COG1472	Belongs to the glycosyl hydrolase 3 family
EYC57_RS22220	COG0246	Mannitol dehydrogenase
EYC57_RS22280	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS22310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EYC57_RS22365	COG1136	(ABC) transporter
EYC57_RS22380	COG1127	ABC transporter
EYC57_RS22385	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EYC57_RS22390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EYC57_RS22415	COG0386	Belongs to the glutathione peroxidase family
EYC57_RS22425	COG1322	Protein conserved in bacteria
EYC57_RS22440	COG0531	amino acid
EYC57_RS22460	COG2199	diguanylate cyclase activity
EYC57_RS22460	COG2203	Gaf domain
EYC57_RS22470	COG1929	Belongs to the glycerate kinase type-1 family
EYC57_RS22475	COG2271	Major facilitator Superfamily
EYC57_RS22490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYC57_RS22500	COG0861	Integral membrane protein TerC family
EYC57_RS22510	COG0584	glycerophosphoryl diester phosphodiesterase
EYC57_RS22520	COG0671	phosphoesterase, PA-phosphatase related
EYC57_RS22545	COG2826	transposase and inactivated derivatives, IS30 family
EYC57_RS22570	COG0582	viral genome integration into host DNA
EYC57_RS22575	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34