locus-tag	class	description
EYC56_RS00025	COG0187	DNA topoisomerase II activity
EYC56_RS00035	COG0501	Belongs to the peptidase M48B family
EYC56_RS00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EYC56_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYC56_RS00115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYC56_RS00125	COG0793	Belongs to the peptidase S41A family
EYC56_RS00130	COG4942	peptidase
EYC56_RS00140	COG2234	aminopeptidase activity
EYC56_RS00150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYC56_RS00165	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYC56_RS00180	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYC56_RS00190	COG1064	alcohol dehydrogenase
EYC56_RS00205	COG0493	'glutamate synthase
EYC56_RS00210	COG0067	glutamate synthase
EYC56_RS00210	COG0070	glutamate synthase
EYC56_RS00210	COG0069	glutamate synthase activity
EYC56_RS00270	COG1111	helicase
EYC56_RS00270	COG1205	dead DEAH box helicase
EYC56_RS00275	COG1272	protein, Hemolysin III
EYC56_RS00300	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EYC56_RS00310	COG4772	TonB-dependent receptor
EYC56_RS00325	COG3039	Transposase
EYC56_RS00330	COG1304	FMN binding
EYC56_RS00335	COG1755	Isoprenylcysteine carboxyl methyltransferase
EYC56_RS00365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYC56_RS00400	COG0477	Major facilitator Superfamily
EYC56_RS00410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC56_RS00425	COG2826	transposase and inactivated derivatives, IS30 family
EYC56_RS00470	COG3237	CsbD-like
EYC56_RS00565	COG3039	Transposase
EYC56_RS00585	COG0246	Mannitol dehydrogenase
EYC56_RS00590	COG1472	Belongs to the glycosyl hydrolase 3 family
EYC56_RS00600	COG4948	Mandelate Racemase Muconate Lactonizing
EYC56_RS00610	COG3661	Belongs to the glycosyl hydrolase 67 family
EYC56_RS00630	COG0037	tRNA processing
EYC56_RS00635	COG2974	May be involved in recombination
EYC56_RS00660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EYC56_RS00670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYC56_RS00675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYC56_RS00680	COG0805	protein transport
EYC56_RS00690	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYC56_RS00690	COG0519	Catalyzes the synthesis of GMP from XMP
EYC56_RS00705	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EYC56_RS00710	COG0752	glycyl-tRNA synthetase alpha subunit
EYC56_RS00725	COG0457	Tetratricopeptide repeat
EYC56_RS00730	COG4771	TonB-dependent receptor
EYC56_RS00735	COG0729	surface antigen
EYC56_RS00740	COG2911	Protein conserved in bacteria
EYC56_RS00755	COG0443	Heat shock 70 kDa protein
EYC56_RS00780	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC56_RS00795	COG3265	gluconokinase activity
EYC56_RS00800	COG2211	Major facilitator Superfamily
EYC56_RS00805	COG3459	Glycosyltransferase 36 associated
EYC56_RS00815	COG2205	protein histidine kinase activity
EYC56_RS00825	COG1414	Transcriptional regulator
EYC56_RS00830	COG0738	Major facilitator superfamily
EYC56_RS00835	COG3254	rhamnose metabolic process
EYC56_RS00840	COG4948	Mandelate Racemase Muconate Lactonizing
EYC56_RS00850	COG0179	Fumarylacetoacetate (FAA) hydrolase
EYC56_RS00855	COG1028	Short-chain dehydrogenase reductase Sdr
EYC56_RS00875	COG3507	Belongs to the glycosyl hydrolase 43 family
EYC56_RS00910	COG3162	membrane
EYC56_RS00915	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYC56_RS00930	COG0708	Exodeoxyribonuclease III
EYC56_RS00945	COG2091	lysine biosynthetic process via aminoadipic acid
EYC56_RS00955	COG3540	Alkaline phosphatase
EYC56_RS00960	COG0357	Ribosomal RNA small subunit methyltransferase G
EYC56_RS00985	COG2159	amidohydrolase
EYC56_RS01000	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EYC56_RS01005	COG0583	DNA-binding transcription factor activity
EYC56_RS01010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYC56_RS01030	COG0210	DNA helicase
EYC56_RS01105	COG0408	coproporphyrinogen oxidase activity
EYC56_RS01155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYC56_RS01170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYC56_RS01215	COG1028	Short-chain dehydrogenase reductase Sdr
EYC56_RS01230	COG0463	Glycosyl transferase, family 2
EYC56_RS01240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYC56_RS01245	COG3100	YcgL domain-containing protein
EYC56_RS01260	COG3387	PFAM Glycoside hydrolase 15-related
EYC56_RS01265	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EYC56_RS01295	COG2239	Acts as a magnesium transporter
EYC56_RS01305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYC56_RS01305	COG1042	CoA-binding domain protein
EYC56_RS01305	COG0045	succinate-CoA ligase (ADP-forming) activity
EYC56_RS01320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYC56_RS01330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYC56_RS01390	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYC56_RS01395	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYC56_RS01400	COG4786	Flagellar basal body rod
EYC56_RS01405	COG4786	Flagellar basal body rod
EYC56_RS01415	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EYC56_RS01420	COG1706	bacterial-type flagellum-dependent cell motility
EYC56_RS01435	COG1677	Flagellar hook-basal body complex protein FliE
EYC56_RS01440	COG1766	The M ring may be actively involved in energy transduction
EYC56_RS01455	COG1157	protein secretion by the type III secretion system
EYC56_RS01470	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EYC56_RS01475	COG1749	Flagellar hook protein flgE
EYC56_RS01505	COG3039	Transposase
EYC56_RS01515	COG3039	Transposase
EYC56_RS01520	COG0028	Belongs to the TPP enzyme family
EYC56_RS01525	COG4191	Histidine kinase
EYC56_RS01550	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EYC56_RS01565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYC56_RS01575	COG0596	Alpha beta hydrolase
EYC56_RS01580	COG0727	PFAM Uncharacterised protein family (UPF0153)
EYC56_RS01585	COG0318	PFAM AMP-dependent synthetase and ligase
EYC56_RS01590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYC56_RS01605	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYC56_RS01620	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EYC56_RS01635	COG0564	pseudouridine synthase activity
EYC56_RS01665	COG0339	signal peptide processing
EYC56_RS01710	COG4770	biotin carboxylase activity
EYC56_RS01715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYC56_RS01720	COG1960	acyl-CoA dehydrogenase activity
EYC56_RS01770	COG0523	cobalamin synthesis protein
EYC56_RS01785	COG0697	spore germination
EYC56_RS01795	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EYC56_RS01800	COG1846	Transcriptional regulator
EYC56_RS01805	COG1764	response to oxidative stress
EYC56_RS01835	COG0656	L-ascorbic acid biosynthetic process
EYC56_RS01840	COG2130	NADP-dependent
EYC56_RS01845	COG0667	Aldo Keto reductase
EYC56_RS01855	COG1187	pseudouridine synthase activity
EYC56_RS01870	COG1643	Atp-dependent helicase
EYC56_RS01880	COG4807	Protein conserved in bacteria
EYC56_RS01885	COG2072	flavoprotein involved in K transport
EYC56_RS01905	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EYC56_RS01960	COG0084	hydrolase, TatD family'
EYC56_RS01980	COG0583	DNA-binding transcription factor activity
EYC56_RS01985	COG2814	Major facilitator Superfamily
EYC56_RS01995	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EYC56_RS02000	COG1902	pentaerythritol trinitrate reductase activity
EYC56_RS02030	COG0745	RESPONSE REGULATOR receiver
EYC56_RS02050	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYC56_RS02055	COG0583	DNA-binding transcription factor activity
EYC56_RS02085	COG0702	epimerase
EYC56_RS02090	COG1733	regulation of RNA biosynthetic process
EYC56_RS02115	COG3039	Transposase
EYC56_RS02145	COG0129	dihydroxy-acid dehydratase activity
EYC56_RS02155	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EYC56_RS02235	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EYC56_RS02240	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EYC56_RS02250	COG3485	protocatechuate 3,4-dioxygenase
EYC56_RS02255	COG3485	protocatechuate 3,4-dioxygenase
EYC56_RS02270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYC56_RS02275	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYC56_RS02290	COG1414	Transcriptional regulator
EYC56_RS02300	COG0657	acetylesterase activity
EYC56_RS02330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYC56_RS02370	COG0156	8-amino-7-oxononanoate synthase activity
EYC56_RS02375	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EYC56_RS02380	COG1040	competence protein
EYC56_RS02385	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EYC56_RS02480	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYC56_RS02555	COG1511	domain protein
EYC56_RS02555	COG3264	Mechanosensitive ion channel
EYC56_RS02570	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EYC56_RS02580	COG2354	Protein conserved in bacteria
EYC56_RS02585	COG1649	PFAM Uncharacterised BCR, COG1649
EYC56_RS02605	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EYC56_RS02630	COG0702	epimerase
EYC56_RS02645	COG1858	cytochrome C peroxidase
EYC56_RS02705	COG4221	oxidoreductase activity
EYC56_RS02730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EYC56_RS02755	COG0463	Glycosyl transferase, family 2
EYC56_RS02770	COG1475	DNA binding
EYC56_RS02775	COG1192	Involved in chromosome partitioning
EYC56_RS02790	COG0708	Exodeoxyribonuclease III
EYC56_RS02795	COG2211	Major facilitator Superfamily
EYC56_RS02815	COG0739	heme binding
EYC56_RS02880	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EYC56_RS02895	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EYC56_RS02960	COG0358	DNA primase activity
EYC56_RS02965	COG1295	ribonuclease BN
EYC56_RS02990	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EYC56_RS02995	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EYC56_RS03015	COG2133	pyrroloquinoline quinone binding
EYC56_RS03020	COG4682	membrane
EYC56_RS03040	COG0531	amino acid
EYC56_RS03065	COG4948	Mandelate Racemase Muconate Lactonizing
EYC56_RS03075	COG3023	N-Acetylmuramoyl-L-alanine amidase
EYC56_RS03080	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EYC56_RS03130	COG5383	Protein conserved in bacteria
EYC56_RS03160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC56_RS03165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC56_RS03170	COG1473	amidohydrolase
EYC56_RS03185	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EYC56_RS03185	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EYC56_RS03225	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EYC56_RS03230	COG3118	belongs to the thioredoxin family
EYC56_RS03240	COG2884	Cell division ATP-binding protein ftsE
EYC56_RS03245	COG2177	Part of the ABC transporter FtsEX involved in
EYC56_RS03250	COG3437	response regulator, receiver
EYC56_RS03255	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EYC56_RS03260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYC56_RS03265	COG2860	membrane
EYC56_RS03270	COG1252	NADH dehydrogenase
EYC56_RS03295	COG0459	protein refolding
EYC56_RS03310	COG3550	peptidyl-serine autophosphorylation
EYC56_RS03315	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EYC56_RS03330	COG3386	PFAM SMP-30 Gluconolaconase
EYC56_RS03345	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EYC56_RS03375	COG2353	YceI-like domain
EYC56_RS03480	COG4221	oxidoreductase activity
EYC56_RS03530	COG0697	spore germination
EYC56_RS03535	COG4305	rare lipoprotein A
EYC56_RS03540	COG5297	Belongs to the glycosyl hydrolase family 6
EYC56_RS03550	COG1113	amino acid transport
EYC56_RS03560	COG0598	Magnesium transport protein CorA
EYC56_RS03625	COG0840	transmembrane signaling receptor activity
EYC56_RS03635	COG5297	Belongs to the glycosyl hydrolase family 6
EYC56_RS03635	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYC56_RS03640	COG0659	secondary active sulfate transmembrane transporter activity
EYC56_RS03675	COG3275	phosphorelay sensor kinase activity
EYC56_RS03685	COG0181	hydroxymethylbilane synthase activity
EYC56_RS03710	COG1505	serine-type exopeptidase activity
EYC56_RS03720	COG0436	Aminotransferase
EYC56_RS03730	COG2832	Protein of unknown function (DUF454)
EYC56_RS03750	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EYC56_RS03765	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EYC56_RS03800	COG3300	MHYT domain
EYC56_RS03800	COG5001	Diguanylate cyclase
EYC56_RS03805	COG0308	aminopeptidase N
EYC56_RS03820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYC56_RS03825	COG1077	Cell shape determining protein MreB Mrl
EYC56_RS03830	COG1792	Involved in formation and maintenance of cell shape
EYC56_RS03845	COG0772	Belongs to the SEDS family
EYC56_RS03895	COG2951	lytic endotransglycosylase activity
EYC56_RS03900	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EYC56_RS03905	COG1686	Belongs to the peptidase S11 family
EYC56_RS03920	COG2921	Belongs to the UPF0250 family
EYC56_RS03945	COG1051	belongs to the nudix hydrolase family
EYC56_RS03945	COG1056	cytidyltransferase-related domain
EYC56_RS03980	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EYC56_RS03985	COG0673	inositol 2-dehydrogenase activity
EYC56_RS03990	COG2823	Periplasmic or secreted lipoprotein
EYC56_RS03995	COG4251	negative regulation of phosphorylation
EYC56_RS04000	COG0784	Response regulator, receiver
EYC56_RS04005	COG4191	Histidine kinase
EYC56_RS04010	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EYC56_RS04045	COG3250	beta-galactosidase activity
EYC56_RS04060	COG2188	Transcriptional regulator
EYC56_RS04070	COG1609	Transcriptional regulator
EYC56_RS04075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYC56_RS04080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EYC56_RS04090	COG1215	transferase activity, transferring glycosyl groups
EYC56_RS04095	COG1649	PFAM Uncharacterised BCR, COG1649
EYC56_RS04095	COG0726	polysaccharide deacetylase
EYC56_RS04155	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EYC56_RS04195	COG2205	protein histidine kinase activity
EYC56_RS04245	COG0488	(ABC) transporter
EYC56_RS04265	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EYC56_RS04275	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EYC56_RS04285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYC56_RS04285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYC56_RS04305	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EYC56_RS04310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYC56_RS04315	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EYC56_RS04340	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EYC56_RS04345	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EYC56_RS04355	COG2205	protein histidine kinase activity
EYC56_RS04360	COG0745	RESPONSE REGULATOR receiver
EYC56_RS04365	COG0277	FAD linked oxidase domain protein
EYC56_RS04370	COG1988	membrane-bound metal-dependent
EYC56_RS04375	COG0792	nuclease activity
EYC56_RS04405	COG0275	rRNA processing
EYC56_RS04410	COG3116	cell division
EYC56_RS04425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EYC56_RS04430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYC56_RS04445	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYC56_RS04450	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYC56_RS04455	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EYC56_RS04470	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EYC56_RS04480	COG4942	peptidase
EYC56_RS04480	COG1388	LysM domain
EYC56_RS04495	COG0494	nUDIX hydrolase
EYC56_RS04510	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EYC56_RS04525	COG3321	synthase
EYC56_RS04525	COG0604	alcohol dehydrogenase
EYC56_RS04525	COG1028	Short-chain dehydrogenase reductase Sdr
EYC56_RS04600	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EYC56_RS04605	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EYC56_RS04645	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EYC56_RS04660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYC56_RS04670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYC56_RS04675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EYC56_RS04685	COG0667	Aldo Keto reductase
EYC56_RS04710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYC56_RS04715	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EYC56_RS04725	COG2175	clavaminate synthase activity
EYC56_RS04735	COG4181	ATPase activity
EYC56_RS04750	COG0642	Histidine kinase
EYC56_RS04765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EYC56_RS04785	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EYC56_RS04805	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EYC56_RS04810	COG2967	ApaG domain
EYC56_RS04815	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EYC56_RS04825	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EYC56_RS04840	COG0123	including yeast histone deacetylase and acetoin utilization protein
EYC56_RS04845	COG2096	Adenosyltransferase
EYC56_RS04855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC56_RS04860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC56_RS04880	COG3039	Transposase
EYC56_RS04885	COG1802	Transcriptional regulator
EYC56_RS04895	COG3384	dioxygenase
EYC56_RS04900	COG0583	DNA-binding transcription factor activity
EYC56_RS04915	COG1024	Enoyl-CoA hydratase
EYC56_RS04935	COG3386	PFAM SMP-30 Gluconolaconase
EYC56_RS04965	COG0697	spore germination
EYC56_RS05005	COG2197	response regulator
EYC56_RS05015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYC56_RS05020	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EYC56_RS05035	COG0583	DNA-binding transcription factor activity
EYC56_RS05040	COG3634	alkyl hydroperoxide reductase activity
EYC56_RS05050	COG2890	protein-(glutamine-N5) methyltransferase activity
EYC56_RS05100	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EYC56_RS05155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYC56_RS05165	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EYC56_RS05195	COG1295	ribonuclease BN
EYC56_RS05200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC56_RS05220	COG0521	Mo-molybdopterin cofactor biosynthetic process
EYC56_RS05230	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EYC56_RS05235	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EYC56_RS05245	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EYC56_RS05260	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYC56_RS05270	COG0193	aminoacyl-tRNA hydrolase activity
EYC56_RS05275	COG0012	GTP binding
EYC56_RS05305	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EYC56_RS05310	COG0250	Participates in transcription elongation, termination and antitermination
EYC56_RS05320	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EYC56_RS05325	COG0081	regulation of translation
EYC56_RS05330	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EYC56_RS05335	COG0222	ribosome binding
EYC56_RS05340	COG0085	RNA polymerase activity
EYC56_RS05345	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EYC56_RS05350	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EYC56_RS05355	COG0049	tRNA binding
EYC56_RS05375	COG0051	transcription antitermination factor activity, RNA binding
EYC56_RS05385	COG0088	Forms part of the polypeptide exit tunnel
EYC56_RS05390	COG0089	rRNA binding
EYC56_RS05395	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EYC56_RS05405	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EYC56_RS05415	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EYC56_RS05420	COG0255	Belongs to the universal ribosomal protein uL29 family
EYC56_RS05425	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EYC56_RS05430	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EYC56_RS05435	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EYC56_RS05460	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EYC56_RS05470	COG1841	ribosomal large subunit assembly
EYC56_RS05475	COG0200	Binds to the 23S rRNA
EYC56_RS05480	COG0201	protein transport
EYC56_RS05495	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EYC56_RS05505	COG0203	ribosomal protein L17
EYC56_RS05510	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EYC56_RS05520	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EYC56_RS05540	COG1217	gtp-binding protein TYPA
EYC56_RS05545	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EYC56_RS05555	COG0625	glutathione transferase activity
EYC56_RS05565	COG0584	glycerophosphoryl diester phosphodiesterase
EYC56_RS05585	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYC56_RS05585	COG1902	pentaerythritol trinitrate reductase activity
EYC56_RS05620	COG0156	8-amino-7-oxononanoate synthase activity
EYC56_RS05625	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EYC56_RS05630	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EYC56_RS05635	COG4208	sulfate ABC transporter
EYC56_RS05640	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EYC56_RS05675	COG0406	alpha-ribazole phosphatase activity
EYC56_RS05685	COG0285	dihydrofolate synthase activity
EYC56_RS05705	COG2833	Protein of unknown function (DUF455)
EYC56_RS05715	COG3291	Pkd domain containing protein
EYC56_RS05725	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYC56_RS05730	COG0671	phosphoesterase, PA-phosphatase related
EYC56_RS05735	COG0438	transferase activity, transferring glycosyl groups
EYC56_RS05745	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EYC56_RS05760	COG4783	chaperone-mediated protein folding
EYC56_RS05780	COG0473	3-isopropylmalate dehydrogenase activity
EYC56_RS05825	COG3852	Histidine kinase
EYC56_RS05835	COG0544	peptidyl-prolyl cis-trans isomerase activity
EYC56_RS05875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYC56_RS05900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EYC56_RS05905	COG0631	protein serine/threonine phosphatase activity
EYC56_RS05920	COG0859	PFAM glycosyl transferase family 9
EYC56_RS05925	COG3642	lipopolysaccharide core region biosynthetic process
EYC56_RS05930	COG1234	tRNA 3'-trailer cleavage
EYC56_RS05935	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EYC56_RS05945	COG0315	cyclic pyranopterin monophosphate synthase activity
EYC56_RS05950	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EYC56_RS05955	COG0314	molybdopterin synthase activity
EYC56_RS05990	COG3039	Transposase
EYC56_RS06020	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EYC56_RS06030	COG0537	adenosine 5'-monophosphoramidase activity
EYC56_RS06050	COG0714	Associated with various cellular activities
EYC56_RS06070	COG1399	metal-binding, possibly nucleic acid-binding protein
EYC56_RS06095	COG1028	Short-chain dehydrogenase reductase Sdr
EYC56_RS06100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYC56_RS06110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EYC56_RS06195	COG1028	Short-chain dehydrogenase reductase Sdr
EYC56_RS06200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYC56_RS06210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EYC56_RS06215	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EYC56_RS06245	COG3829	transcription factor binding
EYC56_RS06260	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EYC56_RS06345	COG0330	HflC and HflK could
EYC56_RS06350	COG0330	HflC and HflK could
EYC56_RS06360	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EYC56_RS06365	COG0308	aminopeptidase N
EYC56_RS06465	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EYC56_RS06500	COG0732	type I restriction modification DNA specificity domain
EYC56_RS06590	COG0587	DNA-directed DNA polymerase activity
EYC56_RS06610	COG1297	OPT oligopeptide transporter protein
EYC56_RS06630	COG1506	peptidase
EYC56_RS06630	COG0823	Involved in the tonB-independent uptake of proteins
EYC56_RS06640	COG1917	Cupin 2, conserved barrel domain protein
EYC56_RS06640	COG2207	Transcriptional regulator
EYC56_RS06680	COG0753	catalase activity
EYC56_RS06715	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EYC56_RS06715	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EYC56_RS06725	COG3551	Protein conserved in bacteria
EYC56_RS06755	COG2194	sulfuric ester hydrolase activity
EYC56_RS06765	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EYC56_RS06770	COG0745	RESPONSE REGULATOR receiver
EYC56_RS06775	COG0642	Histidine kinase
EYC56_RS06785	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EYC56_RS06790	COG2894	cell division
EYC56_RS06805	COG4585	Histidine kinase
EYC56_RS06810	COG2197	response regulator
EYC56_RS06825	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EYC56_RS06850	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EYC56_RS06855	COG2963	transposase activity
EYC56_RS06945	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYC56_RS06955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYC56_RS06965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYC56_RS07000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYC56_RS07080	COG3179	chitinase
EYC56_RS07380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EYC56_RS07395	COG1842	Phage shock protein A
EYC56_RS07420	COG0754	glutathionylspermidine amidase activity
EYC56_RS07490	COG0531	amino acid
EYC56_RS07495	COG2197	response regulator
EYC56_RS07500	COG2267	carboxylic ester hydrolase activity
EYC56_RS07510	COG1113	amino acid transport
EYC56_RS07520	COG1271	oxidase subunit
EYC56_RS07525	COG1294	oxidase, subunit
EYC56_RS07535	COG2239	Acts as a magnesium transporter
EYC56_RS07545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYC56_RS07550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYC56_RS07560	COG1660	Displays ATPase and GTPase activities
EYC56_RS07570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYC56_RS07585	COG1137	ATPase activity
EYC56_RS07590	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EYC56_RS07600	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EYC56_RS07610	COG0271	Belongs to the BolA IbaG family
EYC56_RS07620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYC56_RS07640	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EYC56_RS07655	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EYC56_RS07665	COG0628	permease
EYC56_RS07675	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EYC56_RS07680	COG3178	'Phosphotransferase
EYC56_RS07690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYC56_RS07695	COG1555	photosystem II stabilization
EYC56_RS07710	COG3039	Transposase
EYC56_RS07735	COG3039	Transposase
EYC56_RS07740	COG2146	nitrite reductase [NAD(P)H] activity
EYC56_RS07750	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EYC56_RS07755	COG0719	Fe-S assembly protein
EYC56_RS07760	COG0396	ATPase activity
EYC56_RS07765	COG0719	Fe-S assembly protein
EYC56_RS07770	COG1959	2 iron, 2 sulfur cluster binding
EYC56_RS07825	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EYC56_RS07855	COG0519	Catalyzes the synthesis of GMP from XMP
EYC56_RS07870	COG1678	Uncharacterized ACR, COG1678
EYC56_RS07875	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EYC56_RS07895	COG1764	response to oxidative stress
EYC56_RS07905	COG0384	phenazine biosynthesis protein PhzF
EYC56_RS07915	COG0527	aspartate kinase activity
EYC56_RS07945	COG0142	geranyltranstransferase activity
EYC56_RS07950	COG0629	single-stranded DNA binding
EYC56_RS07960	COG2801	Transposase and inactivated derivatives
EYC56_RS07990	COG4251	negative regulation of phosphorylation
EYC56_RS07990	COG5001	Diguanylate cyclase
EYC56_RS07990	COG3706	GGDEF domain
EYC56_RS07990	COG2203	Gaf domain
EYC56_RS08000	COG2080	2 iron, 2 sulfur cluster binding
EYC56_RS08005	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EYC56_RS08010	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EYC56_RS08015	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EYC56_RS08075	COG2879	small protein
EYC56_RS08080	COG1966	Carbon starvation protein
EYC56_RS08085	COG1741	Belongs to the pirin family
EYC56_RS08200	COG2826	transposase and inactivated derivatives, IS30 family
EYC56_RS08240	COG1741	Belongs to the pirin family
EYC56_RS08250	COG1515	deoxyribonuclease V activity
EYC56_RS08285	COG3501	Rhs element vgr protein
EYC56_RS08285	COG3409	Peptidoglycan-binding domain 1 protein
EYC56_RS08300	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EYC56_RS08305	COG2200	EAL domain
EYC56_RS08305	COG2199	diguanylate cyclase activity
EYC56_RS08305	COG2202	Pas domain
EYC56_RS08310	COG0835	chemotaxis
EYC56_RS08315	COG0840	transmembrane signaling receptor activity
EYC56_RS08325	COG0643	Histidine kinase
EYC56_RS08325	COG2198	Histidine kinase
EYC56_RS08335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EYC56_RS08345	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EYC56_RS08380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYC56_RS08385	COG0735	belongs to the Fur family
EYC56_RS08470	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EYC56_RS08520	COG5002	protein histidine kinase activity
EYC56_RS08520	COG5001	Diguanylate cyclase
EYC56_RS08525	COG1187	pseudouridine synthase activity
EYC56_RS08545	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EYC56_RS08555	COG0475	glutathione-regulated potassium exporter activity
EYC56_RS08560	COG5002	protein histidine kinase activity
EYC56_RS08560	COG5000	phosphorelay sensor kinase activity
EYC56_RS08565	COG0745	RESPONSE REGULATOR receiver
EYC56_RS08595	COG1132	(ABC) transporter
EYC56_RS08675	COG3118	belongs to the thioredoxin family
EYC56_RS08705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EYC56_RS08730	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EYC56_RS08755	COG2968	Membrane
EYC56_RS08770	COG3164	Protein of unknown function
EYC56_RS08780	COG0312	modulator of DNA gyrase
EYC56_RS08790	COG0312	modulator of DNA gyrase
EYC56_RS08805	COG4104	PAAR repeat-containing protein
EYC56_RS08810	COG0142	geranyltranstransferase activity
EYC56_RS08815	COG1722	exodeoxyribonuclease VII activity
EYC56_RS08820	COG0037	tRNA processing
EYC56_RS08825	COG1785	Belongs to the alkaline phosphatase family
EYC56_RS08830	COG1301	dicarboxylic acid transport
EYC56_RS08835	COG4106	trans-aconitate 2-methyltransferase activity
EYC56_RS08850	COG0791	NLP P60 protein
EYC56_RS08855	COG0791	NLP P60 protein
EYC56_RS08860	COG1047	Peptidyl-prolyl cis-trans
EYC56_RS08865	COG2311	Membrane
EYC56_RS08870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC56_RS08945	COG3039	Transposase
EYC56_RS08950	COG0489	protein tyrosine kinase activity
EYC56_RS08960	COG0717	Belongs to the dCTP deaminase family
EYC56_RS08985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYC56_RS09000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYC56_RS09025	COG0433	COG0433 Predicted ATPase
EYC56_RS09055	COG2890	protein-(glutamine-N5) methyltransferase activity
EYC56_RS09060	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EYC56_RS09065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYC56_RS09070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EYC56_RS09090	COG0101	tRNA pseudouridine synthase activity
EYC56_RS09095	COG0135	phosphoribosylanthranilate isomerase activity
EYC56_RS09105	COG0133	tryptophan synthase activity
EYC56_RS09120	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EYC56_RS09125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYC56_RS09165	COG0149	triose-phosphate isomerase activity
EYC56_RS09180	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYC56_RS09190	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYC56_RS09195	COG0649	NAD binding
EYC56_RS09200	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EYC56_RS09205	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EYC56_RS09210	COG1034	ATP synthesis coupled electron transport
EYC56_RS09215	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EYC56_RS09245	COG1007	ATP synthesis coupled electron transport
EYC56_RS09255	COG0779	Required for maturation of 30S ribosomal subunits
EYC56_RS09260	COG0195	Participates in both transcription termination and antitermination
EYC56_RS09265	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EYC56_RS09280	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EYC56_RS09285	COG1185	polyribonucleotide nucleotidyltransferase activity
EYC56_RS09320	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EYC56_RS09330	COG2095	MarC family integral membrane protein
EYC56_RS09345	COG1611	Belongs to the LOG family
EYC56_RS09385	COG4969	Belongs to the N-Me-Phe pilin family
EYC56_RS09390	COG0556	nucleotide-excision repair
EYC56_RS09425	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EYC56_RS09440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EYC56_RS09495	COG0438	transferase activity, transferring glycosyl groups
EYC56_RS09500	COG0438	transferase activity, transferring glycosyl groups
EYC56_RS09510	COG0438	transferase activity, transferring glycosyl groups
EYC56_RS09540	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EYC56_RS09550	COG1960	acyl-CoA dehydrogenase activity
EYC56_RS09560	COG3040	lipid binding
EYC56_RS09580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EYC56_RS09585	COG0784	Response regulator, receiver
EYC56_RS09585	COG4191	Histidine kinase
EYC56_RS09595	COG1194	a g-specific adenine glycosylase
EYC56_RS09610	COG0552	protein localization to endoplasmic reticulum
EYC56_RS09620	COG3938	Belongs to the proline racemase family
EYC56_RS09625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC56_RS09640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYC56_RS09650	COG0006	proline dipeptidase activity
EYC56_RS09665	COG0531	amino acid
EYC56_RS09715	COG4206	TonB-dependent receptor
EYC56_RS09770	COG0326	Molecular chaperone. Has ATPase activity
EYC56_RS09775	COG0742	ribosomal rna small subunit methyltransferase
EYC56_RS09780	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EYC56_RS09795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EYC56_RS09800	COG0405	Gamma-glutamyltransferase
EYC56_RS09855	COG0343	queuine tRNA-ribosyltransferase activity
EYC56_RS09860	COG1862	Preprotein translocase
EYC56_RS09870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYC56_RS09900	COG2826	transposase and inactivated derivatives, IS30 family
EYC56_RS09910	COG2131	deaminase
EYC56_RS09985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYC56_RS09985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYC56_RS09990	COG1105	Belongs to the carbohydrate kinase PfkB family
EYC56_RS09995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYC56_RS09995	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYC56_RS10000	COG1609	Transcriptional regulator
EYC56_RS10010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC56_RS10015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC56_RS10025	COG2902	Dehydrogenase
EYC56_RS10060	COG0784	Response regulator, receiver
EYC56_RS10060	COG2205	protein histidine kinase activity
EYC56_RS10060	COG5002	protein histidine kinase activity
EYC56_RS10065	COG2733	membrane
EYC56_RS10075	COG1121	(ABC) transporter
EYC56_RS10080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EYC56_RS10095	COG0243	molybdopterin cofactor binding
EYC56_RS10105	COG0477	Major facilitator Superfamily
EYC56_RS10115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC56_RS10120	COG0174	glutamine synthetase
EYC56_RS10125	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EYC56_RS10155	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EYC56_RS10175	COG3842	ATPase activity
EYC56_RS10185	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYC56_RS10190	COG1177	transmembrane transport
EYC56_RS10200	COG1012	belongs to the aldehyde dehydrogenase family
EYC56_RS10215	COG4535	Mg2 and Co2 transporter CorC
EYC56_RS10235	COG1702	phosphate starvation-inducible protein PhoH
EYC56_RS10255	COG0741	lytic transglycosylase activity
EYC56_RS10260	COG0723	plastoquinol--plastocyanin reductase activity
EYC56_RS10265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EYC56_RS10270	COG2857	Cytochrome c1
EYC56_RS10275	COG0625	glutathione transferase activity
EYC56_RS10280	COG2969	positive regulation of protein catabolic process
EYC56_RS10310	COG0840	transmembrane signaling receptor activity
EYC56_RS10315	COG0835	chemotaxis
EYC56_RS10325	COG2801	Transposase and inactivated derivatives
EYC56_RS10425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EYC56_RS10495	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYC56_RS10515	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYC56_RS10520	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EYC56_RS10520	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYC56_RS10525	COG0802	atpase or kinase
EYC56_RS10530	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYC56_RS10535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EYC56_RS10560	COG1028	Short-chain dehydrogenase reductase Sdr
EYC56_RS10570	COG0501	Belongs to the peptidase M48B family
EYC56_RS10580	COG2081	HI0933 family
EYC56_RS10585	COG4681	YaeQ
EYC56_RS10590	COG1671	Belongs to the UPF0178 family
EYC56_RS10600	COG0625	glutathione transferase activity
EYC56_RS10610	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EYC56_RS10620	COG0513	Belongs to the DEAD box helicase family
EYC56_RS10625	COG0488	(ABC) transporter
EYC56_RS10650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYC56_RS10655	COG0483	inositol monophosphate 1-phosphatase activity
EYC56_RS10670	COG3300	MHYT domain
EYC56_RS10670	COG5001	Diguanylate cyclase
EYC56_RS10675	COG1509	lysine 2,3-aminomutase activity
EYC56_RS10690	COG0402	S-adenosylhomocysteine deaminase activity
EYC56_RS10695	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EYC56_RS10720	COG4677	pectinesterase activity
EYC56_RS10745	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EYC56_RS10770	COG2166	iron-sulfur cluster assembly
EYC56_RS10790	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EYC56_RS10795	COG0137	argininosuccinate synthase activity
EYC56_RS10800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYC56_RS10805	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYC56_RS10820	COG0165	Argininosuccinate lyase
EYC56_RS10875	COG1271	oxidase subunit
EYC56_RS10885	COG4988	ABC transporter
EYC56_RS10890	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EYC56_RS10900	COG1278	Cold shock
EYC56_RS10950	COG4133	protoheme IX ABC transporter activity
EYC56_RS10955	COG0436	Aminotransferase
EYC56_RS10975	COG1187	pseudouridine synthase activity
EYC56_RS10980	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EYC56_RS10985	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EYC56_RS10990	COG2350	Protein conserved in bacteria
EYC56_RS11020	COG1175	transmembrane transport
EYC56_RS11025	COG0395	ABC-type sugar transport system, permease component
EYC56_RS11050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYC56_RS11060	COG2957	Belongs to the agmatine deiminase family
EYC56_RS11075	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EYC56_RS11080	COG0539	negative regulation of cytoplasmic translation
EYC56_RS11085	COG0776	regulation of translation
EYC56_RS11095	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EYC56_RS11100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYC56_RS11110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EYC56_RS11125	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EYC56_RS11135	COG0519	Catalyzes the synthesis of GMP from XMP
EYC56_RS11135	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYC56_RS11145	COG0464	growth
EYC56_RS11155	COG3002	Belongs to the UPF0753 family
EYC56_RS11160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYC56_RS11165	COG0583	DNA-binding transcription factor activity
EYC56_RS11195	COG0583	DNA-binding transcription factor activity
EYC56_RS11220	COG1914	H( )-stimulated, divalent metal cation uptake system
EYC56_RS11240	COG0668	transmembrane transport
EYC56_RS11250	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EYC56_RS11265	COG1028	Short-chain dehydrogenase reductase Sdr
EYC56_RS11270	COG1183	phosphatidylcholine synthase activity
EYC56_RS11280	COG3243	poly(R)-hydroxyalkanoic acid synthase
EYC56_RS11295	COG0723	plastoquinol--plastocyanin reductase activity
EYC56_RS11295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC56_RS11305	COG2183	response to ionizing radiation
EYC56_RS11325	COG2205	protein histidine kinase activity
EYC56_RS11325	COG0784	Response regulator, receiver
EYC56_RS11415	COG3039	Transposase
EYC56_RS11440	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EYC56_RS11460	COG1054	Belongs to the UPF0176 family
EYC56_RS11475	COG1530	ribonuclease E activity
EYC56_RS11505	COG2154	pterin-4-alpha-carbinolamine dehydratase
EYC56_RS11705	COG0631	protein serine/threonine phosphatase activity
EYC56_RS11710	COG0515	serine threonine protein kinase
EYC56_RS11740	COG1858	cytochrome C peroxidase
EYC56_RS11785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC56_RS11790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC56_RS11975	COG4566	intracellular signal transduction
EYC56_RS11985	COG5001	Diguanylate cyclase
EYC56_RS12005	COG3685	Protein conserved in bacteria
EYC56_RS12045	COG1648	precorrin-2 dehydrogenase activity
EYC56_RS12045	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYC56_RS12070	COG0746	molybdenum cofactor guanylyltransferase activity
EYC56_RS12085	COG0708	Exodeoxyribonuclease III
EYC56_RS12095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EYC56_RS12105	COG0303	'Molybdopterin
EYC56_RS12110	COG1160	GTP binding
EYC56_RS12115	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC56_RS12135	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EYC56_RS12150	COG1024	Enoyl-CoA hydratase
EYC56_RS12150	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYC56_RS12155	COG0183	Belongs to the thiolase family
EYC56_RS12160	COG0038	chloride channel
EYC56_RS12180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EYC56_RS12205	COG1674	ftsk spoiiie
EYC56_RS12210	COG0492	ferredoxin-NADP+ reductase activity
EYC56_RS12235	COG0542	response to heat
EYC56_RS12250	COG0482	sulfurtransferase activity
EYC56_RS12280	COG4585	Histidine kinase
EYC56_RS12290	COG5002	protein histidine kinase activity
EYC56_RS12310	COG0784	Response regulator, receiver
EYC56_RS12310	COG0835	chemotaxis
EYC56_RS12320	COG1558	bacterial-type flagellum-dependent cell motility
EYC56_RS12325	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EYC56_RS12335	COG4787	bacterial-type flagellum-dependent cell motility
EYC56_RS12345	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EYC56_RS12350	COG1706	bacterial-type flagellum-dependent cell motility
EYC56_RS12370	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EYC56_RS12375	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EYC56_RS12405	COG2201	protein-glutamate methylesterase activity
EYC56_RS12425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYC56_RS12435	COG1028	Short-chain dehydrogenase reductase Sdr
EYC56_RS12465	COG2826	transposase and inactivated derivatives, IS30 family
EYC56_RS12485	COG1677	Flagellar hook-basal body complex protein FliE
EYC56_RS12535	COG3190	flagellar
EYC56_RS12555	COG1684	flagellar biosynthetic protein fliR
EYC56_RS12610	COG0784	Response regulator, receiver
EYC56_RS12610	COG0643	Histidine kinase
EYC56_RS12610	COG2198	Histidine kinase
EYC56_RS12640	COG2801	Transposase and inactivated derivatives
EYC56_RS12670	COG0322	excinuclease ABC activity
EYC56_RS12680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYC56_RS12690	COG1663	tetraacyldisaccharide 4'-kinase activity
EYC56_RS12705	COG0811	peptide transport
EYC56_RS12730	COG4591	ABC-type transport system involved in lipoprotein release permease component
EYC56_RS12745	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EYC56_RS12760	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EYC56_RS12775	COG0354	folic acid binding
EYC56_RS12790	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EYC56_RS12800	COG0363	glucosamine-6-phosphate deaminase activity
EYC56_RS12805	COG0129	dihydroxy-acid dehydratase activity
EYC56_RS12810	COG0800	Aldolase
EYC56_RS12950	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYC56_RS12955	COG4774	siderophore transport
EYC56_RS12965	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EYC56_RS12970	COG1360	Flagellar Motor Protein
EYC56_RS12975	COG1192	Involved in chromosome partitioning
EYC56_RS12980	COG0835	chemotaxis
EYC56_RS12990	COG0745	RESPONSE REGULATOR receiver
EYC56_RS13000	COG0840	transmembrane signaling receptor activity
EYC56_RS13025	COG0840	transmembrane signaling receptor activity
EYC56_RS13040	COG0840	transmembrane signaling receptor activity
EYC56_RS13050	COG0840	transmembrane signaling receptor activity
EYC56_RS13060	COG0840	transmembrane signaling receptor activity
EYC56_RS13070	COG0840	transmembrane signaling receptor activity
EYC56_RS13075	COG0840	transmembrane signaling receptor activity
EYC56_RS13080	COG0840	transmembrane signaling receptor activity
EYC56_RS13085	COG0840	transmembrane signaling receptor activity
EYC56_RS13090	COG0840	transmembrane signaling receptor activity
EYC56_RS13110	COG0835	chemotaxis
EYC56_RS13120	COG0840	transmembrane signaling receptor activity
EYC56_RS13155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYC56_RS13185	COG0318	PFAM AMP-dependent synthetase and ligase
EYC56_RS13190	COG1024	Enoyl-CoA hydratase
EYC56_RS13195	COG0784	Response regulator, receiver
EYC56_RS13195	COG2198	Histidine kinase
EYC56_RS13195	COG2205	protein histidine kinase activity
EYC56_RS13220	COG3279	Response regulator of the LytR AlgR family
EYC56_RS13235	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EYC56_RS13245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYC56_RS13250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYC56_RS13260	COG0505	Belongs to the CarA family
EYC56_RS13265	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EYC56_RS13270	COG2258	MOSC domain
EYC56_RS13275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYC56_RS13325	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EYC56_RS13350	COG0277	FAD linked oxidase domain protein
EYC56_RS13355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYC56_RS13365	COG0531	amino acid
EYC56_RS13370	COG0531	amino acid
EYC56_RS13375	COG0235	Class ii aldolase
EYC56_RS13380	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EYC56_RS13400	COG0140	phosphoribosyl-ATP diphosphatase activity
EYC56_RS13400	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EYC56_RS13410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EYC56_RS13420	COG0131	Imidazoleglycerol-phosphate dehydratase
EYC56_RS13420	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EYC56_RS13435	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EYC56_RS13450	COG0124	histidyl-tRNA synthetase
EYC56_RS13470	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EYC56_RS13525	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EYC56_RS13525	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EYC56_RS13570	COG2814	Major facilitator Superfamily
EYC56_RS13650	COG1012	belongs to the aldehyde dehydrogenase family
EYC56_RS13670	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EYC56_RS13675	COG0697	spore germination
EYC56_RS13685	COG1794	racemase activity, acting on amino acids and derivatives
EYC56_RS13705	COG0671	phosphoesterase, PA-phosphatase related
EYC56_RS13720	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EYC56_RS13730	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYC56_RS13740	COG5001	Diguanylate cyclase
EYC56_RS13740	COG4251	negative regulation of phosphorylation
EYC56_RS13740	COG2203	Gaf domain
EYC56_RS13740	COG3706	GGDEF domain
EYC56_RS13760	COG1472	Belongs to the glycosyl hydrolase 3 family
EYC56_RS13790	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EYC56_RS13810	COG0617	tRNA 3'-terminal CCA addition
EYC56_RS13820	COG1469	GTP cyclohydrolase I activity
EYC56_RS13825	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYC56_RS13845	COG0477	Major facilitator Superfamily
EYC56_RS13855	COG1070	Carbohydrate kinase
EYC56_RS13870	COG2826	transposase and inactivated derivatives, IS30 family
EYC56_RS13890	COG0800	Aldolase
EYC56_RS13895	COG4948	Mandelate Racemase Muconate Lactonizing
EYC56_RS13905	COG3734	2-keto-3-deoxy-galactonokinase
EYC56_RS13910	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EYC56_RS13920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYC56_RS13935	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYC56_RS13940	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EYC56_RS13950	COG0352	thiamine-phosphate diphosphorylase activity
EYC56_RS13950	COG0351	phosphomethylpyrimidine kinase
EYC56_RS13975	COG0583	DNA-binding transcription factor activity
EYC56_RS13980	COG1741	Belongs to the pirin family
EYC56_RS14010	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EYC56_RS14040	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EYC56_RS14045	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EYC56_RS14050	COG2137	regulation of response to DNA damage stimulus
EYC56_RS14060	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EYC56_RS14075	COG1546	Belongs to the CinA family
EYC56_RS14080	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EYC56_RS14095	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EYC56_RS14105	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EYC56_RS14110	COG1534	Rna-binding protein
EYC56_RS14125	COG1238	metal cluster binding
EYC56_RS14130	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EYC56_RS14135	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EYC56_RS14140	COG2840	Smr protein MutS2
EYC56_RS14150	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EYC56_RS14165	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EYC56_RS14170	COG0148	phosphopyruvate hydratase activity
EYC56_RS14180	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EYC56_RS14185	COG0504	CTP synthase activity
EYC56_RS14230	COG1253	flavin adenine dinucleotide binding
EYC56_RS14245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYC56_RS14265	COG2271	Major facilitator Superfamily
EYC56_RS14275	COG1132	(ABC) transporter
EYC56_RS14280	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EYC56_RS14295	COG0438	transferase activity, transferring glycosyl groups
EYC56_RS14305	COG2264	protein methyltransferase activity
EYC56_RS14335	COG2244	polysaccharide biosynthetic process
EYC56_RS14385	COG1595	DNA-templated transcription, initiation
EYC56_RS14400	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYC56_RS14420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC56_RS14435	COG4191	Histidine kinase
EYC56_RS14435	COG0784	Response regulator, receiver
EYC56_RS14440	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EYC56_RS14445	COG4191	Histidine kinase
EYC56_RS14445	COG0784	Response regulator, receiver
EYC56_RS14460	COG0840	transmembrane signaling receptor activity
EYC56_RS14530	COG0583	DNA-binding transcription factor activity
EYC56_RS14545	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EYC56_RS14565	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EYC56_RS14570	COG0077	Prephenate dehydratase
EYC56_RS14570	COG1605	Chorismate mutase
EYC56_RS14575	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EYC56_RS14580	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EYC56_RS14625	COG1228	amidohydrolase
EYC56_RS14630	COG2986	histidine ammonia-lyase
EYC56_RS14640	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EYC56_RS14680	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EYC56_RS14695	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EYC56_RS14700	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EYC56_RS14710	COG3115	cell septum assembly
EYC56_RS14730	COG0360	Binds together with S18 to 16S ribosomal RNA
EYC56_RS14735	COG0316	Belongs to the HesB IscA family
EYC56_RS14770	COG0288	reversible hydration of carbon dioxide
EYC56_RS14785	COG3844	kynureninase activity
EYC56_RS14795	COG2925	Exonuclease
EYC56_RS14805	COG0667	Aldo Keto reductase
EYC56_RS14835	COG0116	Belongs to the methyltransferase superfamily
EYC56_RS14835	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYC56_RS14880	COG0494	nUDIX hydrolase
EYC56_RS14890	COG1024	Enoyl-CoA hydratase
EYC56_RS14900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EYC56_RS14905	COG0659	secondary active sulfate transmembrane transporter activity
EYC56_RS14930	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EYC56_RS14935	COG0573	inorganic phosphate transmembrane transporter activity
EYC56_RS14950	COG0704	Plays a role in the regulation of phosphate uptake
EYC56_RS14960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EYC56_RS14970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYC56_RS14985	COG0557	exoribonuclease II activity
EYC56_RS15015	COG1960	acyl-CoA dehydrogenase activity
EYC56_RS15020	COG2226	methyltransferase
EYC56_RS15025	COG0646	methionine synthase
EYC56_RS15025	COG1410	methionine synthase
EYC56_RS15040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYC56_RS15065	COG2900	Belongs to the SlyX family
EYC56_RS15080	COG0386	Belongs to the glutathione peroxidase family
EYC56_RS15090	COG1725	Transcriptional regulator
EYC56_RS15095	COG1131	(ABC) transporter
EYC56_RS15155	COG2850	peptidyl-arginine hydroxylation
EYC56_RS15190	COG1132	(ABC) transporter
EYC56_RS15200	COG0583	DNA-binding transcription factor activity
EYC56_RS15235	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EYC56_RS15245	COG0484	heat shock protein binding
EYC56_RS15250	COG0443	Heat shock 70 kDa protein
EYC56_RS15255	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EYC56_RS15265	COG0497	DNA recombination
EYC56_RS15275	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC56_RS15285	COG2914	Belongs to the UPF0125 (RnfH) family
EYC56_RS15295	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EYC56_RS15320	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EYC56_RS15345	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EYC56_RS15350	COG0174	glutamine synthetase
EYC56_RS15375	COG3706	GGDEF domain
EYC56_RS15395	COG1028	Short-chain dehydrogenase reductase Sdr
EYC56_RS15415	COG0415	Belongs to the DNA photolyase family
EYC56_RS15420	COG0305	Participates in initiation and elongation during chromosome replication
EYC56_RS15430	COG0367	asparagine synthase
EYC56_RS15445	COG1960	acyl-CoA dehydrogenase activity
EYC56_RS15460	COG0084	hydrolase, TatD family'
EYC56_RS15465	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EYC56_RS15505	COG0840	transmembrane signaling receptor activity
EYC56_RS15515	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYC56_RS15565	COG0386	Belongs to the glutathione peroxidase family
EYC56_RS15575	COG0339	signal peptide processing
EYC56_RS15670	COG2814	Major facilitator Superfamily
EYC56_RS15675	COG1566	PFAM secretion protein HlyD family protein
EYC56_RS15690	COG2207	Transcriptional regulator
EYC56_RS15720	COG4774	siderophore transport
EYC56_RS15730	COG0367	asparagine synthase
EYC56_RS15735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYC56_RS15745	COG1393	Belongs to the ArsC family
EYC56_RS15805	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EYC56_RS15820	COG0233	cytoplasmic translational termination
EYC56_RS15830	COG0575	Belongs to the CDS family
EYC56_RS15835	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EYC56_RS15840	COG0750	zinc metalloprotease
EYC56_RS15865	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYC56_RS15870	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYC56_RS15890	COG0825	malonyl-CoA metabolic process
EYC56_RS15915	COG1981	membrane
EYC56_RS15965	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EYC56_RS15980	COG2040	homocysteine
EYC56_RS15985	COG0833	amino acid
EYC56_RS15990	COG0346	lactoylglutathione lyase activity
EYC56_RS16000	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYC56_RS16000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYC56_RS16010	COG2878	Part of a membrane complex involved in electron transport
EYC56_RS16030	COG1595	DNA-templated transcription, initiation
EYC56_RS16055	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYC56_RS16070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYC56_RS16075	COG0251	oxidation-reduction process
EYC56_RS16090	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EYC56_RS16090	COG0392	lysyltransferase activity
EYC56_RS16135	COG2814	Major facilitator Superfamily
EYC56_RS16140	COG1902	pentaerythritol trinitrate reductase activity
EYC56_RS16155	COG2824	Alkylphosphonate utilization operon protein PhnA
EYC56_RS16165	COG1047	Peptidyl-prolyl cis-trans
EYC56_RS16200	COG3039	Transposase
EYC56_RS16215	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EYC56_RS16230	COG1451	nucleotide metabolic process
EYC56_RS16250	COG0183	Belongs to the thiolase family
EYC56_RS16285	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EYC56_RS16285	COG1793	dna ligase
EYC56_RS16295	COG1793	dna ligase
EYC56_RS16300	COG1201	RNA secondary structure unwinding
EYC56_RS16315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC56_RS16320	COG1278	Cold shock
EYC56_RS16325	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EYC56_RS16330	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EYC56_RS16340	COG3046	protein related to deoxyribodipyrimidine photolyase
EYC56_RS16345	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EYC56_RS16350	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EYC56_RS16355	COG2954	triphosphatase activity
EYC56_RS16370	COG1381	Involved in DNA repair and RecF pathway recombination
EYC56_RS16400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYC56_RS16415	COG1024	Enoyl-CoA hydratase
EYC56_RS16415	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYC56_RS16435	COG1024	Enoyl-CoA hydratase
EYC56_RS16440	COG1960	acyl-CoA dehydrogenase activity
EYC56_RS16505	COG0784	Response regulator, receiver
EYC56_RS16505	COG5002	protein histidine kinase activity
EYC56_RS16510	COG0784	Response regulator, receiver
EYC56_RS16510	COG2198	Histidine kinase
EYC56_RS16510	COG2205	protein histidine kinase activity
EYC56_RS16515	COG2353	YceI-like domain
EYC56_RS16540	COG1760	l-serine dehydratase
EYC56_RS16545	COG0460	homoserine dehydrogenase
EYC56_RS16545	COG0527	aspartate kinase activity
EYC56_RS16550	COG0626	cystathionine gamma-synthase activity
EYC56_RS16555	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYC56_RS16560	COG0739	heme binding
EYC56_RS16570	COG1272	protein, Hemolysin III
EYC56_RS16575	COG2982	Protein involved in outer membrane biogenesis
EYC56_RS16580	COG0516	GMP reductase activity
EYC56_RS16580	COG0517	IMP dehydrogenase activity
EYC56_RS16585	COG0463	Glycosyl transferase, family 2
EYC56_RS16595	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EYC56_RS16605	COG4771	TonB-dependent receptor
EYC56_RS16610	COG1309	transcriptional regulator
EYC56_RS16620	COG1960	acyl-CoA dehydrogenase activity
EYC56_RS16655	COG0509	glycine decarboxylation via glycine cleavage system
EYC56_RS16670	COG0330	HflC and HflK could
EYC56_RS16680	COG1742	UPF0060 membrane protein
EYC56_RS16685	COG3956	TIGRFAM MazG family protein
EYC56_RS16695	COG0494	nUDIX hydrolase
EYC56_RS16705	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EYC56_RS16710	COG0837	glucose binding
EYC56_RS16725	COG1388	LysM domain
EYC56_RS16725	COG3858	chitin binding
EYC56_RS16745	COG1472	Belongs to the glycosyl hydrolase 3 family
EYC56_RS16780	COG3039	Transposase
EYC56_RS16790	COG3537	Alpha-1,2-mannosidase
EYC56_RS16840	COG3142	Participates in the control of copper homeostasis
EYC56_RS16845	COG1446	asparaginase
EYC56_RS16880	COG2198	Histidine kinase
EYC56_RS16880	COG0784	Response regulator, receiver
EYC56_RS16880	COG0643	Histidine kinase
EYC56_RS16885	COG0840	transmembrane signaling receptor activity
EYC56_RS16890	COG0835	chemotaxis
EYC56_RS16905	COG0189	ligase activity
EYC56_RS16925	COG1199	ATP-dependent helicase activity
EYC56_RS16935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYC56_RS16940	COG1215	transferase activity, transferring glycosyl groups
EYC56_RS16950	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYC56_RS17005	COG0783	Belongs to the Dps family
EYC56_RS17015	COG0514	ATP-dependent DNA helicase (RecQ)
EYC56_RS17085	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EYC56_RS17095	COG0602	queuosine metabolic process
EYC56_RS17105	COG2885	chlorophyll binding
EYC56_RS17110	COG0823	Involved in the tonB-independent uptake of proteins
EYC56_RS17130	COG0824	Thioesterase
EYC56_RS17135	COG2255	four-way junction helicase activity
EYC56_RS17150	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EYC56_RS17155	COG0217	transcriptional regulatory protein
EYC56_RS17175	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EYC56_RS17190	COG0477	Major facilitator Superfamily
EYC56_RS17205	COG0657	acetylesterase activity
EYC56_RS17205	COG2755	lipolytic protein G-D-S-L family
EYC56_RS17225	COG0488	(ABC) transporter
EYC56_RS17255	COG4651	solute:proton antiporter activity
EYC56_RS17255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EYC56_RS17270	COG4772	TonB-dependent receptor
EYC56_RS17280	COG4264	IucA IucC family
EYC56_RS17285	COG2814	Major facilitator Superfamily
EYC56_RS17295	COG0019	diaminopimelate decarboxylase activity
EYC56_RS17315	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EYC56_RS17350	COG4206	TonB-dependent receptor
EYC56_RS17365	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
EYC56_RS17370	COG0631	protein serine/threonine phosphatase activity
EYC56_RS17375	COG4245	von Willebrand factor, type A
EYC56_RS17400	COG0542	response to heat
EYC56_RS17425	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EYC56_RS17435	COG0534	Mate efflux family protein
EYC56_RS17450	COG0336	Belongs to the RNA methyltransferase TrmD family
EYC56_RS17455	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EYC56_RS17460	COG0228	four-way junction DNA binding
EYC56_RS17485	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EYC56_RS17495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYC56_RS17535	COG2172	sigma factor antagonist activity
EYC56_RS17540	COG1366	Belongs to the anti-sigma-factor antagonist family
EYC56_RS17545	COG1366	Belongs to the anti-sigma-factor antagonist family
EYC56_RS17555	COG0326	Molecular chaperone. Has ATPase activity
EYC56_RS17560	COG2207	Transcriptional regulator
EYC56_RS17595	COG3039	Transposase
EYC56_RS17600	COG3209	COG3209 Rhs family protein
EYC56_RS17620	COG3209	COG3209 Rhs family protein
EYC56_RS17650	COG3209	COG3209 Rhs family protein
EYC56_RS17670	COG3209	COG3209 Rhs family protein
EYC56_RS17690	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EYC56_RS17695	COG1845	cytochrome c oxidase, subunit III
EYC56_RS17700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYC56_RS17715	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EYC56_RS17720	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EYC56_RS17730	COG0196	riboflavin kinase activity
EYC56_RS17735	COG0728	peptidoglycan biosynthetic process
EYC56_RS17740	COG0268	Binds directly to 16S ribosomal RNA
EYC56_RS17745	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EYC56_RS17750	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EYC56_RS17760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EYC56_RS17765	COG0824	Thioesterase
EYC56_RS17780	COG1946	Acyl-CoA thioesterase
EYC56_RS17790	COG1595	DNA-templated transcription, initiation
EYC56_RS17805	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EYC56_RS17845	COG1877	trehalose-phosphatase activity
EYC56_RS17850	COG3387	PFAM Glycoside hydrolase 15-related
EYC56_RS17865	COG0840	transmembrane signaling receptor activity
EYC56_RS17870	COG3011	Protein conserved in bacteria
EYC56_RS17885	COG0564	pseudouridine synthase activity
EYC56_RS17890	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC56_RS17895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYC56_RS17895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EYC56_RS17910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EYC56_RS17915	COG0045	succinate-CoA ligase (ADP-forming) activity
EYC56_RS17950	COG1459	type II secretion system
EYC56_RS17955	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EYC56_RS17960	COG0237	dephospho-CoA kinase activity
EYC56_RS17975	COG2826	transposase and inactivated derivatives, IS30 family
EYC56_RS18000	COG3039	Transposase
EYC56_RS18025	COG0745	RESPONSE REGULATOR receiver
EYC56_RS18030	COG2205	protein histidine kinase activity
EYC56_RS18055	COG2826	transposase and inactivated derivatives, IS30 family
EYC56_RS18125	COG2022	thiamine diphosphate biosynthetic process
EYC56_RS18135	COG0471	metal ion transport
EYC56_RS18135	COG3273	potassium ion transport
EYC56_RS18170	COG1970	mechanosensitive ion channel activity
EYC56_RS18185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYC56_RS18205	COG0308	aminopeptidase N
EYC56_RS18210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC56_RS18220	COG0529	Catalyzes the synthesis of activated sulfate
EYC56_RS18220	COG2895	sulfate adenylyltransferase (ATP) activity
EYC56_RS18225	COG0175	sulfate reduction
EYC56_RS18230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYC56_RS18235	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EYC56_RS18240	COG0175	sulfate reduction
EYC56_RS18260	COG2198	Histidine kinase
EYC56_RS18260	COG2205	protein histidine kinase activity
EYC56_RS18260	COG0784	Response regulator, receiver
EYC56_RS18310	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EYC56_RS18315	COG3588	fructose-bisphosphate aldolase
EYC56_RS18320	COG0469	pyruvate kinase activity
EYC56_RS18345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EYC56_RS18355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYC56_RS18355	COG3453	Protein conserved in bacteria
EYC56_RS18360	COG0725	ABC transporter, periplasmic molybdate-binding protein
EYC56_RS18365	COG4149	molybdate abc transporter
EYC56_RS18370	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EYC56_RS18390	COG0642	Histidine kinase
EYC56_RS18415	COG1022	Amp-dependent synthetase and ligase
EYC56_RS18445	COG1376	ErfK ybiS ycfS ynhG family protein
EYC56_RS18450	COG0739	heme binding
EYC56_RS18465	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EYC56_RS18470	COG1301	dicarboxylic acid transport
EYC56_RS18490	COG2304	oxidoreductase activity
EYC56_RS18510	COG0714	Associated with various cellular activities
EYC56_RS18545	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EYC56_RS18575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EYC56_RS18585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYC56_RS18605	COG1561	YicC-like family, N-terminal region
EYC56_RS18610	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EYC56_RS18615	COG0346	lactoylglutathione lyase activity
EYC56_RS18625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYC56_RS18655	COG0006	proline dipeptidase activity
EYC56_RS18680	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EYC56_RS18700	COG2912	Transglutaminase-like superfamily
EYC56_RS18705	COG1773	rubredoxin
EYC56_RS18710	COG0352	thiamine-phosphate diphosphorylase activity
EYC56_RS18725	COG1396	sequence-specific DNA binding
EYC56_RS18775	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EYC56_RS18825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYC56_RS18830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYC56_RS18840	COG1028	Short-chain dehydrogenase reductase Sdr
EYC56_RS18850	COG0671	phosphoesterase, PA-phosphatase related
EYC56_RS18860	COG3781	membrane
EYC56_RS18870	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYC56_RS18915	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EYC56_RS18925	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EYC56_RS18960	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EYC56_RS18970	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EYC56_RS19000	COG2226	methyltransferase
EYC56_RS19005	COG0066	3-isopropylmalate dehydratase activity
EYC56_RS19010	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EYC56_RS19030	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EYC56_RS19035	COG1538	Outer membrane efflux protein
EYC56_RS19040	COG1519	Transferase
EYC56_RS19045	COG1560	Kdo2-lipid A biosynthetic process
EYC56_RS19075	COG0281	malic enzyme
EYC56_RS19075	COG0280	phosphate acetyltransferase
EYC56_RS19095	COG4191	Histidine kinase
EYC56_RS19110	COG0583	DNA-binding transcription factor activity
EYC56_RS19130	COG2197	response regulator
EYC56_RS19140	COG0642	Histidine kinase
EYC56_RS19160	COG2851	Citrate transporter
EYC56_RS19165	COG1028	Short-chain dehydrogenase reductase Sdr
EYC56_RS19170	COG1609	Transcriptional regulator
EYC56_RS19180	COG2211	Major facilitator Superfamily
EYC56_RS19210	COG0436	Aminotransferase
EYC56_RS19230	COG0726	polysaccharide deacetylase
EYC56_RS19235	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EYC56_RS19250	COG3039	Transposase
EYC56_RS19275	COG3964	amidohydrolase
EYC56_RS19280	COG0402	S-adenosylhomocysteine deaminase activity
EYC56_RS19320	COG0242	peptide deformylase activity
EYC56_RS19340	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EYC56_RS19395	COG2188	Transcriptional regulator
EYC56_RS19405	COG1450	Type ii and iii secretion system protein
EYC56_RS19420	COG3166	PFAM Fimbrial assembly family protein
EYC56_RS19425	COG3156	type II secretion system protein K
EYC56_RS19430	COG4795	General secretion pathway protein
EYC56_RS19435	COG2165	general secretion pathway protein
EYC56_RS19440	COG4970	Tfp pilus assembly protein FimT
EYC56_RS19445	COG2165	general secretion pathway protein
EYC56_RS19450	COG1459	type II secretion system
EYC56_RS19460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EYC56_RS19465	COG1404	Belongs to the peptidase S8 family
EYC56_RS19470	COG5295	Hep Hag repeat protein
EYC56_RS19480	COG0047	phosphoribosylformylglycinamidine synthase activity
EYC56_RS19480	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EYC56_RS19490	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EYC56_RS19495	COG4974	Belongs to the 'phage' integrase family
EYC56_RS19510	COG0795	lipopolysaccharide-transporting ATPase activity
EYC56_RS19520	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EYC56_RS19535	COG0525	valine-tRNA ligase activity
EYC56_RS19565	COG1183	phosphatidylcholine synthase activity
EYC56_RS19575	COG0442	prolyl-tRNA aminoacylation
EYC56_RS19590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EYC56_RS19595	COG1127	ABC transporter
EYC56_RS19600	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EYC56_RS19600	COG3218	ABC-type transport auxiliary lipoprotein component
EYC56_RS19635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYC56_RS19640	COG0662	Cupin 2, conserved barrel domain protein
EYC56_RS19640	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EYC56_RS19665	COG2086	electron transfer activity
EYC56_RS19680	COG0546	phosphoglycolate phosphatase activity
EYC56_RS19680	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EYC56_RS19685	COG0277	FAD linked oxidase domain protein
EYC56_RS19700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYC56_RS19705	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EYC56_RS19735	COG0438	transferase activity, transferring glycosyl groups
EYC56_RS19735	COG1216	Glycosyl transferase, family 2
EYC56_RS19755	COG0626	cystathionine gamma-synthase activity
EYC56_RS19785	COG0625	glutathione transferase activity
EYC56_RS19800	COG0513	Belongs to the DEAD box helicase family
EYC56_RS19810	COG0720	synthase
EYC56_RS19820	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EYC56_RS19825	COG1956	GAF domain-containing protein
EYC56_RS19835	COG0546	phosphoglycolate phosphatase activity
EYC56_RS19865	COG0339	signal peptide processing
EYC56_RS19910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYC56_RS20020	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EYC56_RS20025	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EYC56_RS20030	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EYC56_RS20040	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EYC56_RS20050	COG0356	it plays a direct role in the translocation of protons across the membrane
EYC56_RS20070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYC56_RS20080	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYC56_RS20120	COG2011	ABC-type metal ion transport system permease component
EYC56_RS20130	COG0697	spore germination
EYC56_RS20165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYC56_RS20170	COG1187	pseudouridine synthase activity
EYC56_RS20175	COG2813	Specifically methylates the guanine in position
EYC56_RS20205	COG2202	Pas domain
EYC56_RS20205	COG2205	protein histidine kinase activity
EYC56_RS20230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC56_RS20280	COG0745	RESPONSE REGULATOR receiver
EYC56_RS20295	COG1404	Belongs to the peptidase S8 family
EYC56_RS20310	COG0842	Transport permease protein
EYC56_RS20315	COG1131	(ABC) transporter
EYC56_RS20320	COG0025	NhaP-type Na H and K H
EYC56_RS20330	COG3039	Transposase
EYC56_RS20335	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EYC56_RS20345	COG1573	uracil-dna glycosylase
EYC56_RS20355	COG3384	dioxygenase
EYC56_RS20370	COG0667	Aldo Keto reductase
EYC56_RS20380	COG3590	peptidase
EYC56_RS20400	COG0531	amino acid
EYC56_RS20415	COG2972	Histidine kinase
EYC56_RS20435	COG3685	Protein conserved in bacteria
EYC56_RS20440	COG3546	catalase activity
EYC56_RS20470	COG2204	response regulator
EYC56_RS20485	COG1271	oxidase subunit
EYC56_RS20490	COG1294	oxidase, subunit
EYC56_RS20510	COG1063	alcohol dehydrogenase
EYC56_RS20565	COG1131	(ABC) transporter
EYC56_RS20580	COG0251	oxidation-reduction process
EYC56_RS20595	COG0583	DNA-binding transcription factor activity
EYC56_RS20600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EYC56_RS20635	COG0038	chloride channel
EYC56_RS20645	COG0024	Methionine aminopeptidase
EYC56_RS20665	COG1191	sigma factor activity
EYC56_RS20680	COG4974	Belongs to the 'phage' integrase family
EYC56_RS20715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYC56_RS20725	COG1560	Kdo2-lipid A biosynthetic process
EYC56_RS20775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYC56_RS20775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EYC56_RS20780	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EYC56_RS20785	COG0242	peptide deformylase activity
EYC56_RS20790	COG1652	LysM domain
EYC56_RS20795	COG0758	DNA mediated transformation
EYC56_RS20815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYC56_RS20815	COG1754	DNA topoisomerase type I activity
EYC56_RS20820	COG0009	L-threonylcarbamoyladenylate synthase
EYC56_RS20835	COG1028	Short-chain dehydrogenase reductase Sdr
EYC56_RS20845	COG0616	signal peptide processing
EYC56_RS20850	COG0534	Mate efflux family protein
EYC56_RS20870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYC56_RS20875	COG1324	tolerance protein
EYC56_RS20895	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EYC56_RS20900	COG0511	ligase activity, forming carbon-carbon bonds
EYC56_RS20910	COG0439	Biotin carboxylase
EYC56_RS20965	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EYC56_RS21000	COG0138	bifunctional purine biosynthesis protein purh
EYC56_RS21010	COG0151	Belongs to the GarS family
EYC56_RS21020	COG1289	transmembrane transporter activity
EYC56_RS21025	COG2814	Major facilitator Superfamily
EYC56_RS21035	COG2814	Major facilitator Superfamily
EYC56_RS21055	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EYC56_RS21095	COG0745	RESPONSE REGULATOR receiver
EYC56_RS21130	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EYC56_RS21140	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EYC56_RS21150	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EYC56_RS21155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYC56_RS21165	COG0134	indole-3-glycerol-phosphate synthase activity
EYC56_RS21170	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYC56_RS21210	COG2336	PFAM SpoVT AbrB
EYC56_RS21315	COG3501	Rhs element vgr protein
EYC56_RS21315	COG3409	Peptidoglycan-binding domain 1 protein
EYC56_RS21400	COG0270	DNA (cytosine-5-)-methyltransferase activity
EYC56_RS21420	COG2831	hemolysin activation secretion protein
EYC56_RS21580	COG1518	maintenance of DNA repeat elements
EYC56_RS21585	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EYC56_RS21590	COG3039	Transposase
EYC56_RS21665	COG2003	Belongs to the UPF0758 family
EYC56_RS21690	COG0582	viral genome integration into host DNA
EYC56_RS21715	COG0456	acetyltransferase
EYC56_RS21725	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EYC56_RS21760	COG2111	Na H antiporter
EYC56_RS21760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYC56_RS21765	COG1006	Multisubunit Na H antiporter MnhC subunit
EYC56_RS21770	COG0651	ATP synthesis coupled electron transport
EYC56_RS21780	COG2212	antiporter activity
EYC56_RS21785	COG1320	monovalent cation:proton antiporter activity
EYC56_RS21795	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EYC56_RS21815	COG3104	oligopeptide transport
EYC56_RS21820	COG3483	tryptophan 2,3-dioxygenase activity
EYC56_RS21830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EYC56_RS21845	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYC56_RS21855	COG2826	transposase and inactivated derivatives, IS30 family
EYC56_RS21865	COG3039	Transposase
EYC56_RS21905	COG0606	chelatase, subunit chli
EYC56_RS21925	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EYC56_RS21975	COG1090	epimerase
EYC56_RS21995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYC56_RS22020	COG0628	permease
EYC56_RS22030	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EYC56_RS22040	COG1595	DNA-templated transcription, initiation
EYC56_RS22045	COG0753	catalase activity
EYC56_RS22070	COG0697	spore germination
EYC56_RS22095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYC56_RS22100	COG0180	Tryptophanyl-tRNA synthetase
EYC56_RS22105	COG3237	CsbD-like
EYC56_RS22140	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EYC56_RS22155	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EYC56_RS22160	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EYC56_RS22160	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EYC56_RS22170	COG3228	Belongs to the MtfA family
EYC56_RS22200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYC56_RS22230	COG1566	PFAM secretion protein HlyD family protein
EYC56_RS22355	COG0625	glutathione transferase activity
EYC56_RS22395	COG4555	ABC transporter
EYC56_RS22405	COG1476	TRANSCRIPTIONal
EYC56_RS22425	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYC56_RS22430	COG1131	(ABC) transporter
EYC56_RS22435	COG0842	Transport permease protein
EYC56_RS22445	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EYC56_RS22520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYC56_RS22540	COG2951	lytic endotransglycosylase activity
EYC56_RS22555	COG3039	Transposase
EYC56_RS22615	COG1166	arginine decarboxylase activity
EYC56_RS22620	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EYC56_RS22645	COG0513	Belongs to the DEAD box helicase family
EYC56_RS22675	COG1028	Short-chain dehydrogenase reductase Sdr
EYC56_RS22760	COG5444	nuclease activity
EYC56_RS22885	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
EYC56_RS22945	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EYC56_RS22950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYC56_RS22995	COG0183	Belongs to the thiolase family
EYC56_RS23015	COG2032	superoxide dismutase activity
EYC56_RS23020	COG2032	superoxide dismutase activity
EYC56_RS23030	COG2204	response regulator
EYC56_RS23035	COG3852	Histidine kinase
EYC56_RS23040	COG0004	ammonium transporteR
EYC56_RS23045	COG0347	Belongs to the P(II) protein family
EYC56_RS23050	COG0174	glutamine synthetase
EYC56_RS23055	COG1968	undecaprenyl-diphosphatase activity
EYC56_RS23105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYC56_RS23115	COG2062	phosphohistidine phosphatase, SixA
EYC56_RS23120	COG0489	protein tyrosine kinase activity
EYC56_RS23140	COG1396	sequence-specific DNA binding
EYC56_RS23145	COG3550	peptidyl-serine autophosphorylation
EYC56_RS23150	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EYC56_RS23155	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYC56_RS23170	COG1125	glycine betaine transport
EYC56_RS23170	COG0517	IMP dehydrogenase activity
EYC56_RS23185	COG1119	ATPase activity
EYC56_RS23195	COG1473	amidohydrolase
EYC56_RS23200	COG1752	Esterase of the alpha-beta hydrolase superfamily
EYC56_RS23205	COG4773	Receptor
EYC56_RS23210	COG1522	sequence-specific DNA binding
EYC56_RS23215	COG3186	Phenylalanine-4-hydroxylase
EYC56_RS23235	COG1609	Transcriptional regulator
EYC56_RS23275	COG2826	transposase and inactivated derivatives, IS30 family
EYC56_RS23355	COG2826	transposase and inactivated derivatives, IS30 family
EYC56_RS23425	COG0366	Alpha amylase catalytic
EYC56_RS23430	COG0366	Alpha amylase catalytic
EYC56_RS23440	COG2831	hemolysin activation secretion protein
EYC56_RS23495	COG3039	Transposase
EYC56_RS23510	COG3039	Transposase
EYC56_RS23530	COG3210	domain, Protein
EYC56_RS23565	COG3039	Transposase
EYC56_RS23610	COG3693	PFAM glycoside hydrolase, family 10
EYC56_RS23635	COG2211	Major facilitator Superfamily
EYC56_RS23675	COG0604	alcohol dehydrogenase
EYC56_RS23675	COG1028	Short-chain dehydrogenase reductase Sdr
EYC56_RS23675	COG3321	synthase
EYC56_RS23680	COG2937	Belongs to the GPAT DAPAT family
EYC56_RS23715	COG0284	orotidine-5'-phosphate decarboxylase activity
EYC56_RS23720	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EYC56_RS23725	COG3132	Protein of unknown function, DUF480
EYC56_RS23740	COG0210	DNA helicase
EYC56_RS23755	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EYC56_RS23765	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EYC56_RS23795	COG3135	benzoate transporter
EYC56_RS23815	COG0676	glucose-6-phosphate 1-epimerase activity
EYC56_RS23830	COG0730	response to heat
EYC56_RS23860	COG0302	gtp cyclohydrolase
EYC56_RS23975	COG0477	Major facilitator Superfamily
EYC56_RS23990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYC56_RS24015	COG2826	transposase and inactivated derivatives, IS30 family
EYC56_RS24070	COG0564	pseudouridine synthase activity
EYC56_RS24150	COG1074	ATP-dependent DNA helicase activity
EYC56_RS24155	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EYC56_RS24175	COG3039	Transposase
EYC56_RS24180	COG3039	Transposase
EYC56_RS24190	COG1136	(ABC) transporter
EYC56_RS24205	COG1127	ABC transporter
EYC56_RS24210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EYC56_RS24215	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EYC56_RS24230	COG2853	Lipoprotein
EYC56_RS24240	COG0386	Belongs to the glutathione peroxidase family
EYC56_RS24250	COG1322	Protein conserved in bacteria
EYC56_RS24265	COG0531	amino acid
EYC56_RS24290	COG2203	Gaf domain
EYC56_RS24290	COG2199	diguanylate cyclase activity
EYC56_RS24300	COG1929	Belongs to the glycerate kinase type-1 family
EYC56_RS24305	COG2271	Major facilitator Superfamily
EYC56_RS24320	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYC56_RS24330	COG0861	Integral membrane protein TerC family
EYC56_RS24340	COG0584	glycerophosphoryl diester phosphodiesterase
EYC56_RS24350	COG0671	phosphoesterase, PA-phosphatase related
EYC56_RS24355	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EYC56_RS24360	COG0726	polysaccharide deacetylase