locus-tag	class	description
KFK26_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KFK26_RS00020	COG0187	DNA topoisomerase II activity
KFK26_RS00030	COG0501	Belongs to the peptidase M48B family
KFK26_RS00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KFK26_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFK26_RS00085	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KFK26_RS00095	COG4772	TonB-dependent receptor
KFK26_RS00110	COG3039	Transposase
KFK26_RS00115	COG1304	FMN binding
KFK26_RS00135	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KFK26_RS00145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFK26_RS00240	COG2826	transposase and inactivated derivatives, IS30 family
KFK26_RS00265	COG3039	Transposase
KFK26_RS00275	COG1090	epimerase
KFK26_RS00295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFK26_RS00405	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KFK26_RS00480	COG1511	domain protein
KFK26_RS00480	COG3264	Mechanosensitive ion channel
KFK26_RS00495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KFK26_RS00500	COG2354	Protein conserved in bacteria
KFK26_RS00505	COG1649	PFAM Uncharacterised BCR, COG1649
KFK26_RS00515	COG0297	glycogen (starch) synthase activity
KFK26_RS00525	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KFK26_RS00550	COG0702	epimerase
KFK26_RS00565	COG1858	cytochrome C peroxidase
KFK26_RS00635	COG0513	Belongs to the DEAD box helicase family
KFK26_RS00645	COG3039	Transposase
KFK26_RS00690	COG1136	(ABC) transporter
KFK26_RS00730	COG1136	(ABC) transporter
KFK26_RS00770	COG1272	protein, Hemolysin III
KFK26_RS00775	COG1111	helicase
KFK26_RS00775	COG1205	dead DEAH box helicase
KFK26_RS00835	COG0070	glutamate synthase
KFK26_RS00835	COG0067	glutamate synthase
KFK26_RS00835	COG0069	glutamate synthase activity
KFK26_RS00840	COG0493	'glutamate synthase
KFK26_RS00890	COG1609	Transcriptional regulator
KFK26_RS00915	COG0366	Alpha amylase catalytic
KFK26_RS00920	COG0366	Alpha amylase catalytic
KFK26_RS00980	COG0606	chelatase, subunit chli
KFK26_RS01025	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KFK26_RS01030	COG1166	arginine decarboxylase activity
KFK26_RS01095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KFK26_RS01120	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_RS01145	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KFK26_RS01160	COG0210	DNA helicase
KFK26_RS01175	COG3132	Protein of unknown function, DUF480
KFK26_RS01180	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KFK26_RS01185	COG0284	orotidine-5'-phosphate decarboxylase activity
KFK26_RS01220	COG2937	Belongs to the GPAT DAPAT family
KFK26_RS01270	COG1752	Esterase of the alpha-beta hydrolase superfamily
KFK26_RS01280	COG1119	ATPase activity
KFK26_RS01295	COG0517	IMP dehydrogenase activity
KFK26_RS01295	COG1125	glycine betaine transport
KFK26_RS01310	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFK26_RS01315	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
KFK26_RS01320	COG3550	peptidyl-serine autophosphorylation
KFK26_RS01325	COG1396	sequence-specific DNA binding
KFK26_RS01345	COG0489	protein tyrosine kinase activity
KFK26_RS01350	COG2062	phosphohistidine phosphatase, SixA
KFK26_RS01360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFK26_RS01400	COG1968	undecaprenyl-diphosphatase activity
KFK26_RS01405	COG0174	glutamine synthetase
KFK26_RS01410	COG0347	Belongs to the P(II) protein family
KFK26_RS01415	COG0004	ammonium transporteR
KFK26_RS01420	COG3852	Histidine kinase
KFK26_RS01425	COG2204	response regulator
KFK26_RS01430	COG2032	superoxide dismutase activity
KFK26_RS01435	COG2032	superoxide dismutase activity
KFK26_RS01470	COG1196	nuclear chromosome segregation
KFK26_RS01480	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KFK26_RS01485	COG1074	ATP-dependent DNA helicase activity
KFK26_RS01495	COG3549	Plasmid maintenance system killer
KFK26_RS01585	COG1764	response to oxidative stress
KFK26_RS01590	COG1846	Transcriptional regulator
KFK26_RS01675	COG2211	Major facilitator Superfamily
KFK26_RS01700	COG3693	PFAM glycoside hydrolase, family 10
KFK26_RS01725	COG0246	Mannitol dehydrogenase
KFK26_RS01730	COG1472	Belongs to the glycosyl hydrolase 3 family
KFK26_RS01740	COG4948	Mandelate Racemase Muconate Lactonizing
KFK26_RS01750	COG3661	Belongs to the glycosyl hydrolase 67 family
KFK26_RS01770	COG0037	tRNA processing
KFK26_RS01775	COG2974	May be involved in recombination
KFK26_RS01800	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KFK26_RS01810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KFK26_RS01820	COG0805	protein transport
KFK26_RS01830	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFK26_RS01830	COG0519	Catalyzes the synthesis of GMP from XMP
KFK26_RS01845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFK26_RS01850	COG0752	glycyl-tRNA synthetase alpha subunit
KFK26_RS01860	COG0457	Tetratricopeptide repeat
KFK26_RS01865	COG4771	TonB-dependent receptor
KFK26_RS01880	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KFK26_RS01900	COG0523	cobalamin synthesis protein
KFK26_RS01955	COG1960	acyl-CoA dehydrogenase activity
KFK26_RS01960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KFK26_RS01965	COG4770	biotin carboxylase activity
KFK26_RS02025	COG2351	hydroxyisourate hydrolase activity
KFK26_RS02050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KFK26_RS02100	COG0084	hydrolase, TatD family'
KFK26_RS02115	COG0583	DNA-binding transcription factor activity
KFK26_RS02120	COG2814	Major facilitator Superfamily
KFK26_RS02130	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KFK26_RS02135	COG1902	pentaerythritol trinitrate reductase activity
KFK26_RS02165	COG0745	RESPONSE REGULATOR receiver
KFK26_RS02185	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFK26_RS02190	COG0583	DNA-binding transcription factor activity
KFK26_RS02220	COG0702	epimerase
KFK26_RS02225	COG1733	regulation of RNA biosynthetic process
KFK26_RS02275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFK26_RS02325	COG2911	Protein conserved in bacteria
KFK26_RS02330	COG0729	surface antigen
KFK26_RS02345	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KFK26_RS02350	COG3118	belongs to the thioredoxin family
KFK26_RS02360	COG2884	Cell division ATP-binding protein ftsE
KFK26_RS02365	COG2177	Part of the ABC transporter FtsEX involved in
KFK26_RS02370	COG2201	protein-glutamate methylesterase activity
KFK26_RS02375	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KFK26_RS02380	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFK26_RS02390	COG1252	NADH dehydrogenase
KFK26_RS02415	COG0459	protein refolding
KFK26_RS02435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KFK26_RS02465	COG3386	PFAM SMP-30 Gluconolaconase
KFK26_RS02515	COG0778	Nitroreductase
KFK26_RS02520	COG2353	YceI-like domain
KFK26_RS02605	COG0408	coproporphyrinogen oxidase activity
KFK26_RS02635	COG0129	dihydroxy-acid dehydratase activity
KFK26_RS02645	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KFK26_RS02675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFK26_RS02680	COG0318	PFAM AMP-dependent synthetase and ligase
KFK26_RS02685	COG0727	PFAM Uncharacterised protein family (UPF0153)
KFK26_RS02690	COG0596	Alpha beta hydrolase
KFK26_RS02705	COG3177	Filamentation induced by cAMP protein fic
KFK26_RS02710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFK26_RS02725	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KFK26_RS02750	COG4191	Histidine kinase
KFK26_RS02755	COG0028	Belongs to the TPP enzyme family
KFK26_RS02770	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KFK26_RS02775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KFK26_RS02810	COG5383	Protein conserved in bacteria
KFK26_RS02820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFK26_RS02825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFK26_RS02835	COG1473	amidohydrolase
KFK26_RS02845	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KFK26_RS02845	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KFK26_RS02915	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KFK26_RS02920	COG0134	indole-3-glycerol-phosphate synthase activity
KFK26_RS02930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFK26_RS02935	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KFK26_RS02945	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KFK26_RS02950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KFK26_RS02955	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KFK26_RS03005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KFK26_RS03020	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KFK26_RS03085	COG3039	Transposase
KFK26_RS03110	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KFK26_RS03130	COG0534	Mate efflux family protein
KFK26_RS03135	COG0616	signal peptide processing
KFK26_RS03145	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_RS03160	COG0009	L-threonylcarbamoyladenylate synthase
KFK26_RS03165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KFK26_RS03165	COG1754	DNA topoisomerase type I activity
KFK26_RS03180	COG2922	Belongs to the Smg family
KFK26_RS03185	COG0758	DNA mediated transformation
KFK26_RS03190	COG1652	LysM domain
KFK26_RS03195	COG0242	peptide deformylase activity
KFK26_RS03200	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFK26_RS03205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KFK26_RS03205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFK26_RS03255	COG1560	Kdo2-lipid A biosynthetic process
KFK26_RS03265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFK26_RS03410	COG0358	DNA primase activity
KFK26_RS03415	COG1295	ribonuclease BN
KFK26_RS03430	COG1610	YqeY-like protein
KFK26_RS03440	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KFK26_RS03445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KFK26_RS03480	COG2133	pyrroloquinoline quinone binding
KFK26_RS03485	COG4682	membrane
KFK26_RS03515	COG0531	amino acid
KFK26_RS03545	COG4948	Mandelate Racemase Muconate Lactonizing
KFK26_RS03555	COG3023	N-Acetylmuramoyl-L-alanine amidase
KFK26_RS03560	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KFK26_RS03630	COG0183	Belongs to the thiolase family
KFK26_RS03675	COG3483	tryptophan 2,3-dioxygenase activity
KFK26_RS03680	COG3104	oligopeptide transport
KFK26_RS03700	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KFK26_RS03710	COG1320	monovalent cation:proton antiporter activity
KFK26_RS03715	COG2212	antiporter activity
KFK26_RS03725	COG0651	ATP synthesis coupled electron transport
KFK26_RS03730	COG1006	Multisubunit Na H antiporter MnhC subunit
KFK26_RS03735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KFK26_RS03735	COG2111	Na H antiporter
KFK26_RS03775	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KFK26_RS03785	COG0456	acetyltransferase
KFK26_RS03815	COG4221	oxidoreductase activity
KFK26_RS03875	COG0697	spore germination
KFK26_RS03880	COG4305	rare lipoprotein A
KFK26_RS03885	COG5297	Belongs to the glycosyl hydrolase family 6
KFK26_RS03895	COG1113	amino acid transport
KFK26_RS03905	COG0598	Magnesium transport protein CorA
KFK26_RS03925	COG3039	Transposase
KFK26_RS03985	COG5297	Belongs to the glycosyl hydrolase family 6
KFK26_RS03985	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFK26_RS03990	COG0659	secondary active sulfate transmembrane transporter activity
KFK26_RS04035	COG3275	phosphorelay sensor kinase activity
KFK26_RS04045	COG0181	hydroxymethylbilane synthase activity
KFK26_RS04070	COG1505	serine-type exopeptidase activity
KFK26_RS04085	COG0436	Aminotransferase
KFK26_RS04115	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KFK26_RS04145	COG0308	aminopeptidase N
KFK26_RS04150	COG2199	diguanylate cyclase activity
KFK26_RS04195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFK26_RS04200	COG1077	Cell shape determining protein MreB Mrl
KFK26_RS04205	COG1792	Involved in formation and maintenance of cell shape
KFK26_RS04220	COG0772	Belongs to the SEDS family
KFK26_RS04255	COG5632	N-Acetylmuramoyl-L-alanine amidase
KFK26_RS04255	COG3409	Peptidoglycan-binding domain 1 protein
KFK26_RS04255	COG1388	LysM domain
KFK26_RS04275	COG2951	lytic endotransglycosylase activity
KFK26_RS04280	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KFK26_RS04285	COG1686	Belongs to the peptidase S11 family
KFK26_RS04300	COG2921	Belongs to the UPF0250 family
KFK26_RS04325	COG1051	belongs to the nudix hydrolase family
KFK26_RS04325	COG1056	cytidyltransferase-related domain
KFK26_RS04360	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KFK26_RS04365	COG0673	inositol 2-dehydrogenase activity
KFK26_RS04370	COG2823	Periplasmic or secreted lipoprotein
KFK26_RS04375	COG4251	negative regulation of phosphorylation
KFK26_RS04380	COG0784	Response regulator, receiver
KFK26_RS04385	COG4191	Histidine kinase
KFK26_RS04390	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KFK26_RS04440	COG3250	beta-galactosidase activity
KFK26_RS04455	COG2188	Transcriptional regulator
KFK26_RS04465	COG1609	Transcriptional regulator
KFK26_RS04470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFK26_RS04475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KFK26_RS04485	COG1215	transferase activity, transferring glycosyl groups
KFK26_RS04490	COG0726	polysaccharide deacetylase
KFK26_RS04490	COG1649	PFAM Uncharacterised BCR, COG1649
KFK26_RS04595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KFK26_RS04605	COG3039	Transposase
KFK26_RS04640	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KFK26_RS04685	COG2205	protein histidine kinase activity
KFK26_RS04715	COG3791	Glutathione-dependent formaldehyde-activating
KFK26_RS04740	COG0488	(ABC) transporter
KFK26_RS04760	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KFK26_RS04780	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFK26_RS04780	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFK26_RS04800	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KFK26_RS04805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFK26_RS04810	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KFK26_RS04830	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KFK26_RS04835	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KFK26_RS04845	COG2205	protein histidine kinase activity
KFK26_RS04850	COG0745	RESPONSE REGULATOR receiver
KFK26_RS04855	COG0277	FAD linked oxidase domain protein
KFK26_RS04860	COG1988	membrane-bound metal-dependent
KFK26_RS04865	COG0792	nuclease activity
KFK26_RS04900	COG0275	rRNA processing
KFK26_RS04905	COG3116	cell division
KFK26_RS04920	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KFK26_RS04925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFK26_RS04940	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFK26_RS04945	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFK26_RS04950	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KFK26_RS04965	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KFK26_RS04975	COG1388	LysM domain
KFK26_RS04975	COG4942	peptidase
KFK26_RS04980	COG0653	protein targeting
KFK26_RS04990	COG0494	nUDIX hydrolase
KFK26_RS05005	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KFK26_RS05015	COG0604	alcohol dehydrogenase
KFK26_RS05015	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_RS05015	COG3321	synthase
KFK26_RS05060	COG2226	methyltransferase
KFK26_RS05065	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KFK26_RS05110	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KFK26_RS05125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFK26_RS05135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFK26_RS05140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KFK26_RS05150	COG3039	Transposase
KFK26_RS05160	COG0667	Aldo Keto reductase
KFK26_RS05200	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KFK26_RS05210	COG2175	clavaminate synthase activity
KFK26_RS05220	COG4181	ATPase activity
KFK26_RS05235	COG0642	Histidine kinase
KFK26_RS05255	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KFK26_RS05275	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KFK26_RS05295	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KFK26_RS05300	COG2967	ApaG domain
KFK26_RS05305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KFK26_RS05315	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KFK26_RS05330	COG0123	including yeast histone deacetylase and acetoin utilization protein
KFK26_RS05335	COG2096	Adenosyltransferase
KFK26_RS05345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFK26_RS05350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFK26_RS05390	COG0583	DNA-binding transcription factor activity
KFK26_RS05395	COG0318	PFAM AMP-dependent synthetase and ligase
KFK26_RS05405	COG1024	Enoyl-CoA hydratase
KFK26_RS05425	COG3386	PFAM SMP-30 Gluconolaconase
KFK26_RS05435	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KFK26_RS05515	COG3039	Transposase
KFK26_RS05540	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFK26_RS05565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KFK26_RS05570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFK26_RS05575	COG0583	DNA-binding transcription factor activity
KFK26_RS05580	COG3634	alkyl hydroperoxide reductase activity
KFK26_RS05590	COG2890	protein-(glutamine-N5) methyltransferase activity
KFK26_RS05630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFK26_RS05630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFK26_RS05645	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KFK26_RS05670	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KFK26_RS05695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KFK26_RS05705	COG1404	Belongs to the peptidase S8 family
KFK26_RS05710	COG1404	Belongs to the peptidase S8 family
KFK26_RS05715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KFK26_RS05745	COG1295	ribonuclease BN
KFK26_RS05750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFK26_RS05770	COG0521	Mo-molybdopterin cofactor biosynthetic process
KFK26_RS05780	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KFK26_RS05785	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KFK26_RS05795	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KFK26_RS05810	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KFK26_RS05820	COG0193	aminoacyl-tRNA hydrolase activity
KFK26_RS05825	COG0012	GTP binding
KFK26_RS05855	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KFK26_RS05860	COG0250	Participates in transcription elongation, termination and antitermination
KFK26_RS05865	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KFK26_RS05870	COG0081	regulation of translation
KFK26_RS05875	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KFK26_RS05880	COG0222	ribosome binding
KFK26_RS05885	COG0085	RNA polymerase activity
KFK26_RS05890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFK26_RS05895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KFK26_RS05900	COG0049	tRNA binding
KFK26_RS05920	COG0051	transcription antitermination factor activity, RNA binding
KFK26_RS05925	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KFK26_RS05930	COG0088	Forms part of the polypeptide exit tunnel
KFK26_RS05935	COG0089	rRNA binding
KFK26_RS05950	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KFK26_RS05960	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KFK26_RS05965	COG0255	Belongs to the universal ribosomal protein uL29 family
KFK26_RS05970	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KFK26_RS05975	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KFK26_RS05980	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KFK26_RS05985	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KFK26_RS06005	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KFK26_RS06015	COG1841	ribosomal large subunit assembly
KFK26_RS06025	COG0201	protein transport
KFK26_RS06035	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KFK26_RS06040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KFK26_RS06050	COG0203	ribosomal protein L17
KFK26_RS06110	COG3551	Protein conserved in bacteria
KFK26_RS06140	COG2194	sulfuric ester hydrolase activity
KFK26_RS06150	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KFK26_RS06155	COG0745	RESPONSE REGULATOR receiver
KFK26_RS06160	COG0642	Histidine kinase
KFK26_RS06170	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KFK26_RS06175	COG2894	cell division
KFK26_RS06190	COG4585	Histidine kinase
KFK26_RS06195	COG2197	response regulator
KFK26_RS06210	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KFK26_RS06235	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KFK26_RS06310	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFK26_RS06320	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFK26_RS06335	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFK26_RS06355	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFK26_RS06385	COG3039	Transposase
KFK26_RS06405	COG3039	Transposase
KFK26_RS06425	COG3039	Transposase
KFK26_RS06445	COG1741	Belongs to the pirin family
KFK26_RS06455	COG1515	deoxyribonuclease V activity
KFK26_RS06460	COG0588	phosphoglycerate mutase activity
KFK26_RS06475	COG3590	peptidase
KFK26_RS06490	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KFK26_RS06495	COG2199	diguanylate cyclase activity
KFK26_RS06495	COG2200	EAL domain
KFK26_RS06495	COG2202	Pas domain
KFK26_RS06500	COG0835	chemotaxis
KFK26_RS06505	COG0840	transmembrane signaling receptor activity
KFK26_RS06515	COG3039	Transposase
KFK26_RS06535	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KFK26_RS06545	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KFK26_RS06585	COG3039	Transposase
KFK26_RS06645	COG3039	Transposase
KFK26_RS06670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KFK26_RS06675	COG0735	belongs to the Fur family
KFK26_RS06735	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KFK26_RS06740	COG0084	hydrolase, TatD family'
KFK26_RS06755	COG1960	acyl-CoA dehydrogenase activity
KFK26_RS06770	COG0367	asparagine synthase
KFK26_RS06780	COG0305	Participates in initiation and elongation during chromosome replication
KFK26_RS06785	COG0415	Belongs to the DNA photolyase family
KFK26_RS06900	COG5001	Diguanylate cyclase
KFK26_RS06900	COG5002	protein histidine kinase activity
KFK26_RS06905	COG1187	pseudouridine synthase activity
KFK26_RS06925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KFK26_RS06935	COG0475	glutathione-regulated potassium exporter activity
KFK26_RS06940	COG5002	protein histidine kinase activity
KFK26_RS06940	COG5000	phosphorelay sensor kinase activity
KFK26_RS06945	COG0745	RESPONSE REGULATOR receiver
KFK26_RS06975	COG1132	(ABC) transporter
KFK26_RS07015	COG3209	COG3209 Rhs family protein
KFK26_RS07025	COG3039	Transposase
KFK26_RS07060	COG3039	Transposase
KFK26_RS07070	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KFK26_RS07080	COG4969	Belongs to the N-Me-Phe pilin family
KFK26_RS07085	COG2194	sulfuric ester hydrolase activity
KFK26_RS07105	COG2184	nucleotidyltransferase activity
KFK26_RS07130	COG0045	succinate-CoA ligase (ADP-forming) activity
KFK26_RS07135	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KFK26_RS07145	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KFK26_RS07145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFK26_RS07150	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFK26_RS07155	COG0564	pseudouridine synthase activity
KFK26_RS07180	COG3387	PFAM Glycoside hydrolase 15-related
KFK26_RS07185	COG1877	trehalose-phosphatase activity
KFK26_RS07220	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KFK26_RS07245	COG1946	Acyl-CoA thioesterase
KFK26_RS07260	COG0824	Thioesterase
KFK26_RS07265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KFK26_RS07275	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KFK26_RS07280	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KFK26_RS07285	COG0268	Binds directly to 16S ribosomal RNA
KFK26_RS07290	COG0728	peptidoglycan biosynthetic process
KFK26_RS07295	COG0196	riboflavin kinase activity
KFK26_RS07305	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KFK26_RS07310	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KFK26_RS07325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFK26_RS07330	COG1845	cytochrome c oxidase, subunit III
KFK26_RS07335	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KFK26_RS07360	COG3209	COG3209 Rhs family protein
KFK26_RS07380	COG3209	COG3209 Rhs family protein
KFK26_RS07405	COG3209	COG3209 Rhs family protein
KFK26_RS07405	COG3209	COG3209 Rhs family protein
KFK26_RS07410	COG3039	Transposase
KFK26_RS07445	COG3039	Transposase
KFK26_RS07505	COG3039	Transposase
KFK26_RS07605	COG0631	protein serine/threonine phosphatase activity
KFK26_RS07610	COG0515	serine threonine protein kinase
KFK26_RS07640	COG1858	cytochrome C peroxidase
KFK26_RS07700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFK26_RS07725	COG2201	protein-glutamate methylesterase activity
KFK26_RS07755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFK26_RS07775	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KFK26_RS07790	COG1595	DNA-templated transcription, initiation
KFK26_RS07840	COG2244	polysaccharide biosynthetic process
KFK26_RS07870	COG2264	protein methyltransferase activity
KFK26_RS07880	COG0438	transferase activity, transferring glycosyl groups
KFK26_RS07895	COG1136	(ABC) transporter
KFK26_RS07900	COG1132	(ABC) transporter
KFK26_RS07910	COG0477	Major facilitator Superfamily
KFK26_RS07920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFK26_RS07935	COG1253	flavin adenine dinucleotide binding
KFK26_RS07945	COG0306	phosphate transporter
KFK26_RS07975	COG0504	CTP synthase activity
KFK26_RS07980	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KFK26_RS07990	COG0148	phosphopyruvate hydratase activity
KFK26_RS07995	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KFK26_RS08000	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KFK26_RS08010	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KFK26_RS08020	COG2840	Smr protein MutS2
KFK26_RS08025	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KFK26_RS08030	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KFK26_RS08035	COG1238	metal cluster binding
KFK26_RS08050	COG1534	Rna-binding protein
KFK26_RS08055	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KFK26_RS08065	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KFK26_RS08070	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KFK26_RS08080	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KFK26_RS08085	COG1546	Belongs to the CinA family
KFK26_RS08100	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KFK26_RS08105	COG2137	regulation of response to DNA damage stimulus
KFK26_RS08110	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KFK26_RS08115	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KFK26_RS08135	COG0305	Participates in initiation and elongation during chromosome replication
KFK26_RS08140	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KFK26_RS08165	COG1741	Belongs to the pirin family
KFK26_RS08170	COG0583	DNA-binding transcription factor activity
KFK26_RS08195	COG0351	phosphomethylpyrimidine kinase
KFK26_RS08205	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KFK26_RS08210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KFK26_RS08225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFK26_RS08235	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KFK26_RS08240	COG3734	2-keto-3-deoxy-galactonokinase
KFK26_RS08250	COG4948	Mandelate Racemase Muconate Lactonizing
KFK26_RS08255	COG0800	Aldolase
KFK26_RS08270	COG1501	Belongs to the glycosyl hydrolase 31 family
KFK26_RS08280	COG1070	Carbohydrate kinase
KFK26_RS08290	COG0477	Major facilitator Superfamily
KFK26_RS08310	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KFK26_RS08355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KFK26_RS08360	COG2258	MOSC domain
KFK26_RS08370	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KFK26_RS08375	COG0505	Belongs to the CarA family
KFK26_RS08385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KFK26_RS08390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFK26_RS08400	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KFK26_RS08455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KFK26_RS08465	COG2205	protein histidine kinase activity
KFK26_RS08465	COG2198	Histidine kinase
KFK26_RS08465	COG0784	Response regulator, receiver
KFK26_RS08470	COG1024	Enoyl-CoA hydratase
KFK26_RS08475	COG0318	PFAM AMP-dependent synthetase and ligase
KFK26_RS08505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFK26_RS08535	COG0840	transmembrane signaling receptor activity
KFK26_RS08555	COG0835	chemotaxis
KFK26_RS08575	COG0840	transmembrane signaling receptor activity
KFK26_RS08580	COG0840	transmembrane signaling receptor activity
KFK26_RS08585	COG0840	transmembrane signaling receptor activity
KFK26_RS08590	COG0840	transmembrane signaling receptor activity
KFK26_RS08600	COG0840	transmembrane signaling receptor activity
KFK26_RS08610	COG0840	transmembrane signaling receptor activity
KFK26_RS08640	COG0745	RESPONSE REGULATOR receiver
KFK26_RS08650	COG0835	chemotaxis
KFK26_RS08665	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KFK26_RS08685	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KFK26_RS08695	COG4771	TonB-dependent receptor
KFK26_RS08730	COG3501	Rhs element vgr protein
KFK26_RS08730	COG3409	Peptidoglycan-binding domain 1 protein
KFK26_RS08750	COG3501	Rhs element vgr protein
KFK26_RS08750	COG3409	Peptidoglycan-binding domain 1 protein
KFK26_RS08815	COG3039	Transposase
KFK26_RS08825	COG3039	Transposase
KFK26_RS08840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFK26_RS08840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFK26_RS08845	COG1105	Belongs to the carbohydrate kinase PfkB family
KFK26_RS08850	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFK26_RS08850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFK26_RS08855	COG1609	Transcriptional regulator
KFK26_RS08880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFK26_RS08885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFK26_RS08895	COG2902	Dehydrogenase
KFK26_RS08900	COG3039	Transposase
KFK26_RS08910	COG5002	protein histidine kinase activity
KFK26_RS08910	COG2205	protein histidine kinase activity
KFK26_RS08910	COG0784	Response regulator, receiver
KFK26_RS08915	COG2733	membrane
KFK26_RS08925	COG1121	(ABC) transporter
KFK26_RS08930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KFK26_RS08935	COG2223	nitrite transmembrane transporter activity
KFK26_RS08945	COG0243	molybdopterin cofactor binding
KFK26_RS08955	COG0477	Major facilitator Superfamily
KFK26_RS08965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFK26_RS08970	COG0174	glutamine synthetase
KFK26_RS09005	COG3842	ATPase activity
KFK26_RS09025	COG1012	belongs to the aldehyde dehydrogenase family
KFK26_RS09040	COG4535	Mg2 and Co2 transporter CorC
KFK26_RS09060	COG1702	phosphate starvation-inducible protein PhoH
KFK26_RS09065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFK26_RS09085	COG0741	lytic transglycosylase activity
KFK26_RS09090	COG0723	plastoquinol--plastocyanin reductase activity
KFK26_RS09095	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KFK26_RS09100	COG2857	Cytochrome c1
KFK26_RS09105	COG0625	glutathione transferase activity
KFK26_RS09110	COG2969	positive regulation of protein catabolic process
KFK26_RS09135	COG2094	Belongs to the DNA glycosylase MPG family
KFK26_RS09145	COG3328	transposase activity
KFK26_RS09215	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFK26_RS09230	COG1570	exodeoxyribonuclease VII activity
KFK26_RS09235	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFK26_RS09240	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KFK26_RS09240	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KFK26_RS09245	COG0802	atpase or kinase
KFK26_RS09250	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFK26_RS09255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KFK26_RS09275	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_RS09285	COG0501	Belongs to the peptidase M48B family
KFK26_RS09295	COG2081	HI0933 family
KFK26_RS09300	COG4681	YaeQ
KFK26_RS09305	COG1671	Belongs to the UPF0178 family
KFK26_RS09315	COG0625	glutathione transferase activity
KFK26_RS09325	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KFK26_RS09330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KFK26_RS09335	COG0513	Belongs to the DEAD box helicase family
KFK26_RS09340	COG0488	(ABC) transporter
KFK26_RS09360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KFK26_RS09365	COG0483	inositol monophosphate 1-phosphatase activity
KFK26_RS09380	COG3300	MHYT domain
KFK26_RS09380	COG5001	Diguanylate cyclase
KFK26_RS09385	COG1509	lysine 2,3-aminomutase activity
KFK26_RS09400	COG0402	S-adenosylhomocysteine deaminase activity
KFK26_RS09405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KFK26_RS09430	COG4677	pectinesterase activity
KFK26_RS09450	COG3039	Transposase
KFK26_RS09480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KFK26_RS09510	COG2166	iron-sulfur cluster assembly
KFK26_RS09525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KFK26_RS09530	COG0137	argininosuccinate synthase activity
KFK26_RS09540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFK26_RS09545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KFK26_RS09560	COG0165	Argininosuccinate lyase
KFK26_RS09580	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KFK26_RS09615	COG4988	ABC transporter
KFK26_RS09620	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KFK26_RS09720	COG0742	ribosomal rna small subunit methyltransferase
KFK26_RS09725	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KFK26_RS09735	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KFK26_RS09740	COG0405	Gamma-glutamyltransferase
KFK26_RS09805	COG3039	Transposase
KFK26_RS09845	COG0343	queuine tRNA-ribosyltransferase activity
KFK26_RS09850	COG1862	Preprotein translocase
KFK26_RS09855	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFK26_RS09860	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFK26_RS09870	COG3039	Transposase
KFK26_RS09890	COG3328	transposase activity
KFK26_RS09905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFK26_RS09915	COG0704	Plays a role in the regulation of phosphate uptake
KFK26_RS09930	COG0573	inorganic phosphate transmembrane transporter activity
KFK26_RS09935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KFK26_RS09970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KFK26_RS09980	COG1024	Enoyl-CoA hydratase
KFK26_RS09995	COG0494	nUDIX hydrolase
KFK26_RS10040	COG0116	Belongs to the methyltransferase superfamily
KFK26_RS10040	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KFK26_RS10065	COG0667	Aldo Keto reductase
KFK26_RS10075	COG2925	Exonuclease
KFK26_RS10085	COG3844	kynureninase activity
KFK26_RS10100	COG0288	reversible hydration of carbon dioxide
KFK26_RS10130	COG0316	Belongs to the HesB IscA family
KFK26_RS10135	COG0360	Binds together with S18 to 16S ribosomal RNA
KFK26_RS10145	COG0359	binds to the 23S rRNA
KFK26_RS10155	COG3115	cell septum assembly
KFK26_RS10175	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KFK26_RS10190	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KFK26_RS10215	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KFK26_RS10225	COG2986	histidine ammonia-lyase
KFK26_RS10230	COG1228	amidohydrolase
KFK26_RS10270	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KFK26_RS10275	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KFK26_RS10280	COG0077	Prephenate dehydratase
KFK26_RS10280	COG1605	Chorismate mutase
KFK26_RS10285	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KFK26_RS10315	COG4566	intracellular signal transduction
KFK26_RS10365	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFK26_RS10370	COG1469	GTP cyclohydrolase I activity
KFK26_RS10380	COG0617	tRNA 3'-terminal CCA addition
KFK26_RS10390	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KFK26_RS10395	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KFK26_RS10405	COG0166	Belongs to the GPI family
KFK26_RS10425	COG1472	Belongs to the glycosyl hydrolase 3 family
KFK26_RS10440	COG5001	Diguanylate cyclase
KFK26_RS10440	COG2203	Gaf domain
KFK26_RS10440	COG3706	GGDEF domain
KFK26_RS10440	COG4251	negative regulation of phosphorylation
KFK26_RS10525	COG0386	Belongs to the glutathione peroxidase family
KFK26_RS10595	COG1247	-acetyltransferase
KFK26_RS10615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFK26_RS10640	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFK26_RS10660	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFK26_RS10665	COG1393	Belongs to the ArsC family
KFK26_RS10670	COG0431	NADPH-dependent FMN reductase
KFK26_RS10675	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KFK26_RS10680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KFK26_RS10705	COG0784	Response regulator, receiver
KFK26_RS10705	COG5002	protein histidine kinase activity
KFK26_RS10705	COG2205	protein histidine kinase activity
KFK26_RS10745	COG0800	Aldolase
KFK26_RS10750	COG0129	dihydroxy-acid dehydratase activity
KFK26_RS10755	COG0363	glucosamine-6-phosphate deaminase activity
KFK26_RS10765	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFK26_RS10780	COG0354	folic acid binding
KFK26_RS10795	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KFK26_RS10810	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KFK26_RS10825	COG4591	ABC-type transport system involved in lipoprotein release permease component
KFK26_RS10850	COG0811	peptide transport
KFK26_RS10865	COG1663	tetraacyldisaccharide 4'-kinase activity
KFK26_RS10875	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFK26_RS10885	COG0322	excinuclease ABC activity
KFK26_RS10920	COG3328	transposase activity
KFK26_RS10945	COG2201	protein-glutamate methylesterase activity
KFK26_RS11100	COG0140	phosphoribosyl-ATP diphosphatase activity
KFK26_RS11100	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KFK26_RS11110	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KFK26_RS11120	COG0131	Imidazoleglycerol-phosphate dehydratase
KFK26_RS11120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KFK26_RS11135	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KFK26_RS11165	COG0124	histidyl-tRNA synthetase
KFK26_RS11180	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KFK26_RS11225	COG1012	belongs to the aldehyde dehydrogenase family
KFK26_RS11245	COG0167	dihydroorotate dehydrogenase activity
KFK26_RS11250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KFK26_RS11255	COG0697	spore germination
KFK26_RS11280	COG0671	phosphoesterase, PA-phosphatase related
KFK26_RS11295	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KFK26_RS11310	COG2183	response to ionizing radiation
KFK26_RS11320	COG0723	plastoquinol--plastocyanin reductase activity
KFK26_RS11320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFK26_RS11335	COG3243	poly(R)-hydroxyalkanoic acid synthase
KFK26_RS11345	COG1183	phosphatidylcholine synthase activity
KFK26_RS11350	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_RS11365	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KFK26_RS11375	COG0668	transmembrane transport
KFK26_RS11395	COG1914	H( )-stimulated, divalent metal cation uptake system
KFK26_RS11430	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_RS11445	COG0583	DNA-binding transcription factor activity
KFK26_RS11450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KFK26_RS11455	COG3002	Belongs to the UPF0753 family
KFK26_RS11460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFK26_RS11460	COG0519	Catalyzes the synthesis of GMP from XMP
KFK26_RS11470	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KFK26_RS11490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KFK26_RS11500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFK26_RS11505	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KFK26_RS11515	COG0776	regulation of translation
KFK26_RS11520	COG0539	negative regulation of cytoplasmic translation
KFK26_RS11525	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KFK26_RS11540	COG2957	Belongs to the agmatine deiminase family
KFK26_RS11550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFK26_RS11575	COG0395	ABC-type sugar transport system, permease component
KFK26_RS11580	COG1175	transmembrane transport
KFK26_RS11610	COG2350	Protein conserved in bacteria
KFK26_RS11615	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KFK26_RS11620	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KFK26_RS11625	COG1187	pseudouridine synthase activity
KFK26_RS11650	COG0436	Aminotransferase
KFK26_RS11715	COG0277	FAD linked oxidase domain protein
KFK26_RS11720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KFK26_RS11730	COG0531	amino acid
KFK26_RS11735	COG0531	amino acid
KFK26_RS11740	COG0235	Class ii aldolase
KFK26_RS11745	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KFK26_RS11750	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KFK26_RS11785	COG3039	Transposase
KFK26_RS11795	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KFK26_RS11865	COG0303	'Molybdopterin
KFK26_RS11875	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFK26_RS11885	COG1426	Protein conserved in bacteria
KFK26_RS11895	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KFK26_RS11910	COG1024	Enoyl-CoA hydratase
KFK26_RS11910	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFK26_RS11915	COG0183	Belongs to the thiolase family
KFK26_RS11920	COG0038	chloride channel
KFK26_RS11940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KFK26_RS11960	COG1674	ftsk spoiiie
KFK26_RS11965	COG0492	ferredoxin-NADP+ reductase activity
KFK26_RS12000	COG0542	response to heat
KFK26_RS12015	COG0482	sulfurtransferase activity
KFK26_RS12040	COG5001	Diguanylate cyclase
KFK26_RS12045	COG4585	Histidine kinase
KFK26_RS12055	COG5002	protein histidine kinase activity
KFK26_RS12075	COG0784	Response regulator, receiver
KFK26_RS12075	COG0835	chemotaxis
KFK26_RS12085	COG1558	bacterial-type flagellum-dependent cell motility
KFK26_RS12090	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KFK26_RS12100	COG4787	bacterial-type flagellum-dependent cell motility
KFK26_RS12135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KFK26_RS12140	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KFK26_RS12170	COG2201	protein-glutamate methylesterase activity
KFK26_RS12190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFK26_RS12200	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_RS12230	COG1677	Flagellar hook-basal body complex protein FliE
KFK26_RS12280	COG3190	flagellar
KFK26_RS12295	COG1684	flagellar biosynthetic protein fliR
KFK26_RS12350	COG0643	Histidine kinase
KFK26_RS12350	COG0784	Response regulator, receiver
KFK26_RS12350	COG2198	Histidine kinase
KFK26_RS12385	COG3209	COG3209 Rhs family protein
KFK26_RS12410	COG3209	COG3209 Rhs family protein
KFK26_RS12470	COG0583	DNA-binding transcription factor activity
KFK26_RS12480	COG3039	Transposase
KFK26_RS12570	COG3328	transposase activity
KFK26_RS12600	COG3039	Transposase
KFK26_RS12610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFK26_RS12625	COG0557	exoribonuclease II activity
KFK26_RS12650	COG1960	acyl-CoA dehydrogenase activity
KFK26_RS12655	COG2226	methyltransferase
KFK26_RS12660	COG0646	methionine synthase
KFK26_RS12660	COG1410	methionine synthase
KFK26_RS12665	COG1410	methionine synthase
KFK26_RS12665	COG0646	methionine synthase
KFK26_RS12675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFK26_RS12685	COG1609	Transcriptional regulator
KFK26_RS12700	COG2900	Belongs to the SlyX family
KFK26_RS12720	COG0386	Belongs to the glutathione peroxidase family
KFK26_RS12730	COG1725	Transcriptional regulator
KFK26_RS12735	COG1131	(ABC) transporter
KFK26_RS12810	COG2850	peptidyl-arginine hydroxylation
KFK26_RS12845	COG1132	(ABC) transporter
KFK26_RS12870	COG0287	Prephenate dehydrogenase
KFK26_RS12870	COG1605	Chorismate mutase
KFK26_RS12875	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KFK26_RS12880	COG0484	heat shock protein binding
KFK26_RS12885	COG0443	Heat shock 70 kDa protein
KFK26_RS12890	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KFK26_RS12900	COG0497	DNA recombination
KFK26_RS12910	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFK26_RS12915	COG2914	Belongs to the UPF0125 (RnfH) family
KFK26_RS12925	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KFK26_RS12940	COG1960	acyl-CoA dehydrogenase activity
KFK26_RS12950	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KFK26_RS12995	COG2814	Major facilitator Superfamily
KFK26_RS13000	COG1566	PFAM secretion protein HlyD family protein
KFK26_RS13015	COG2207	Transcriptional regulator
KFK26_RS13040	COG4774	siderophore transport
KFK26_RS13050	COG0367	asparagine synthase
KFK26_RS13055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFK26_RS13065	COG1393	Belongs to the ArsC family
KFK26_RS13125	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KFK26_RS13140	COG0233	cytoplasmic translational termination
KFK26_RS13150	COG0575	Belongs to the CDS family
KFK26_RS13155	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KFK26_RS13160	COG0750	zinc metalloprotease
KFK26_RS13185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KFK26_RS13190	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFK26_RS13210	COG0825	malonyl-CoA metabolic process
KFK26_RS13220	COG4771	TonB-dependent receptor
KFK26_RS13225	COG1131	(ABC) transporter
KFK26_RS13250	COG1981	membrane
KFK26_RS13295	COG2895	sulfate adenylyltransferase (ATP) activity
KFK26_RS13295	COG0529	Catalyzes the synthesis of activated sulfate
KFK26_RS13335	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KFK26_RS13355	COG2040	homocysteine
KFK26_RS13360	COG0833	amino acid
KFK26_RS13380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFK26_RS13380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFK26_RS13390	COG2878	Part of a membrane complex involved in electron transport
KFK26_RS13405	COG1595	DNA-templated transcription, initiation
KFK26_RS13430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFK26_RS13445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFK26_RS13450	COG0251	oxidation-reduction process
KFK26_RS13460	COG0392	lysyltransferase activity
KFK26_RS13460	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KFK26_RS13495	COG2814	Major facilitator Superfamily
KFK26_RS13500	COG1902	pentaerythritol trinitrate reductase activity
KFK26_RS13510	COG2824	Alkylphosphonate utilization operon protein PhnA
KFK26_RS13525	COG1047	Peptidyl-prolyl cis-trans
KFK26_RS13560	COG3039	Transposase
KFK26_RS13565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KFK26_RS13580	COG1451	nucleotide metabolic process
KFK26_RS13600	COG0183	Belongs to the thiolase family
KFK26_RS13630	COG1793	dna ligase
KFK26_RS13630	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KFK26_RS13640	COG1793	dna ligase
KFK26_RS13645	COG1201	RNA secondary structure unwinding
KFK26_RS13670	COG1278	Cold shock
KFK26_RS13675	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KFK26_RS13680	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KFK26_RS13690	COG3046	protein related to deoxyribodipyrimidine photolyase
KFK26_RS13695	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
KFK26_RS13715	COG2954	triphosphatase activity
KFK26_RS13730	COG1381	Involved in DNA repair and RecF pathway recombination
KFK26_RS13755	COG0481	GTPase activity
KFK26_RS13760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFK26_RS13775	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFK26_RS13775	COG1024	Enoyl-CoA hydratase
KFK26_RS13795	COG1024	Enoyl-CoA hydratase
KFK26_RS13800	COG1960	acyl-CoA dehydrogenase activity
KFK26_RS13870	COG2353	YceI-like domain
KFK26_RS13880	COG2353	YceI-like domain
KFK26_RS13895	COG1760	l-serine dehydratase
KFK26_RS13905	COG0626	cystathionine gamma-synthase activity
KFK26_RS13910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFK26_RS13915	COG0739	heme binding
KFK26_RS13920	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KFK26_RS13925	COG1272	protein, Hemolysin III
KFK26_RS13955	COG0463	Glycosyl transferase, family 2
KFK26_RS13965	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KFK26_RS13975	COG4771	TonB-dependent receptor
KFK26_RS13980	COG1309	transcriptional regulator
KFK26_RS13990	COG1960	acyl-CoA dehydrogenase activity
KFK26_RS14020	COG0509	glycine decarboxylation via glycine cleavage system
KFK26_RS14025	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KFK26_RS14035	COG0330	HflC and HflK could
KFK26_RS14050	COG3956	TIGRFAM MazG family protein
KFK26_RS14060	COG0494	nUDIX hydrolase
KFK26_RS14070	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KFK26_RS14075	COG0837	glucose binding
KFK26_RS14090	COG1388	LysM domain
KFK26_RS14090	COG3858	chitin binding
KFK26_RS14100	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KFK26_RS14110	COG1472	Belongs to the glycosyl hydrolase 3 family
KFK26_RS14175	COG3537	Alpha-1,2-mannosidase
KFK26_RS14220	COG1446	asparaginase
KFK26_RS14230	COG2304	oxidoreductase activity
KFK26_RS14235	COG2304	oxidoreductase activity
KFK26_RS14265	COG2198	Histidine kinase
KFK26_RS14265	COG0784	Response regulator, receiver
KFK26_RS14265	COG0643	Histidine kinase
KFK26_RS14270	COG0840	transmembrane signaling receptor activity
KFK26_RS14275	COG0835	chemotaxis
KFK26_RS14290	COG0189	ligase activity
KFK26_RS14300	COG1397	ADP-ribosylglycohydrolase
KFK26_RS14310	COG1199	ATP-dependent helicase activity
KFK26_RS14320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFK26_RS14325	COG1215	transferase activity, transferring glycosyl groups
KFK26_RS14335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFK26_RS14350	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
KFK26_RS14355	COG0535	radical SAM domain protein
KFK26_RS14360	COG0535	radical SAM domain protein
KFK26_RS14385	COG1643	Atp-dependent helicase
KFK26_RS14390	COG0783	Belongs to the Dps family
KFK26_RS14395	COG0514	ATP-dependent DNA helicase (RecQ)
KFK26_RS14420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KFK26_RS14445	COG0602	queuosine metabolic process
KFK26_RS14455	COG2885	chlorophyll binding
KFK26_RS14460	COG0823	Involved in the tonB-independent uptake of proteins
KFK26_RS14470	COG0848	biopolymer transport protein
KFK26_RS14480	COG0824	Thioesterase
KFK26_RS14485	COG2255	four-way junction helicase activity
KFK26_RS14495	COG0632	four-way junction helicase activity
KFK26_RS14500	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KFK26_RS14505	COG0217	transcriptional regulatory protein
KFK26_RS14520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KFK26_RS14535	COG0477	Major facilitator Superfamily
KFK26_RS14630	COG0316	Belongs to the HesB IscA family
KFK26_RS14630	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KFK26_RS14635	COG2154	pterin-4-alpha-carbinolamine dehydratase
KFK26_RS14650	COG3064	Membrane
KFK26_RS14660	COG1530	ribonuclease E activity
KFK26_RS14675	COG1054	Belongs to the UPF0176 family
KFK26_RS14695	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KFK26_RS14740	COG3039	Transposase
KFK26_RS14745	COG3039	Transposase
KFK26_RS14790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KFK26_RS14790	COG1648	precorrin-2 dehydrogenase activity
KFK26_RS14815	COG0746	molybdenum cofactor guanylyltransferase activity
KFK26_RS14890	COG4206	TonB-dependent receptor
KFK26_RS14920	COG0531	amino acid
KFK26_RS14935	COG0006	proline dipeptidase activity
KFK26_RS14945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFK26_RS14960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFK26_RS14965	COG3938	Belongs to the proline racemase family
KFK26_RS14975	COG0552	protein localization to endoplasmic reticulum
KFK26_RS14995	COG0784	Response regulator, receiver
KFK26_RS14995	COG4191	Histidine kinase
KFK26_RS15085	COG3040	lipid binding
KFK26_RS15125	COG0438	transferase activity, transferring glycosyl groups
KFK26_RS15135	COG0438	transferase activity, transferring glycosyl groups
KFK26_RS15140	COG0438	transferase activity, transferring glycosyl groups
KFK26_RS15195	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KFK26_RS15200	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KFK26_RS15210	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KFK26_RS15250	COG0556	nucleotide-excision repair
KFK26_RS15255	COG4969	Belongs to the N-Me-Phe pilin family
KFK26_RS15270	COG3039	Transposase
KFK26_RS15325	COG4695	Portal protein
KFK26_RS15370	COG3179	chitinase
KFK26_RS15575	COG1611	Belongs to the LOG family
KFK26_RS15590	COG2095	MarC family integral membrane protein
KFK26_RS15600	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KFK26_RS15635	COG1185	polyribonucleotide nucleotidyltransferase activity
KFK26_RS15640	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KFK26_RS15655	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KFK26_RS15660	COG0195	Participates in both transcription termination and antitermination
KFK26_RS15665	COG0779	Required for maturation of 30S ribosomal subunits
KFK26_RS15675	COG1007	ATP synthesis coupled electron transport
KFK26_RS15705	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KFK26_RS15710	COG1034	ATP synthesis coupled electron transport
KFK26_RS15715	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KFK26_RS15720	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KFK26_RS15725	COG0649	NAD binding
KFK26_RS15730	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFK26_RS15740	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFK26_RS15755	COG0149	triose-phosphate isomerase activity
KFK26_RS15805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFK26_RS15810	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KFK26_RS15815	COG0159	tryptophan synthase activity
KFK26_RS15825	COG0133	tryptophan synthase activity
KFK26_RS15835	COG0135	phosphoribosylanthranilate isomerase activity
KFK26_RS15840	COG0101	tRNA pseudouridine synthase activity
KFK26_RS15860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KFK26_RS15865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFK26_RS15870	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KFK26_RS15875	COG2890	protein-(glutamine-N5) methyltransferase activity
KFK26_RS15925	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFK26_RS15955	COG0717	Belongs to the dCTP deaminase family
KFK26_RS15960	COG0489	protein tyrosine kinase activity
KFK26_RS16005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFK26_RS16010	COG2311	Membrane
KFK26_RS16015	COG1047	Peptidyl-prolyl cis-trans
KFK26_RS16020	COG0791	NLP P60 protein
KFK26_RS16025	COG0791	NLP P60 protein
KFK26_RS16050	COG1785	Belongs to the alkaline phosphatase family
KFK26_RS16055	COG0037	tRNA processing
KFK26_RS16060	COG1722	exodeoxyribonuclease VII activity
KFK26_RS16065	COG0142	geranyltranstransferase activity
KFK26_RS16090	COG0312	modulator of DNA gyrase
KFK26_RS16095	COG3028	Belongs to the UPF0307 family
KFK26_RS16100	COG0312	modulator of DNA gyrase
KFK26_RS16110	COG3164	Protein of unknown function
KFK26_RS16125	COG2968	Membrane
KFK26_RS16155	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KFK26_RS16180	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KFK26_RS16195	COG0495	leucyl-tRNA aminoacylation
KFK26_RS16205	COG3118	belongs to the thioredoxin family
KFK26_RS16250	COG3039	Transposase
KFK26_RS16270	COG3039	Transposase
KFK26_RS16355	COG2022	thiamine diphosphate biosynthetic process
KFK26_RS16365	COG3273	potassium ion transport
KFK26_RS16365	COG0471	metal ion transport
KFK26_RS16395	COG1970	mechanosensitive ion channel activity
KFK26_RS16415	COG2272	Belongs to the type-B carboxylesterase lipase family
KFK26_RS16420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFK26_RS16440	COG0308	aminopeptidase N
KFK26_RS16445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFK26_RS16455	COG3039	Transposase
KFK26_RS16465	COG2895	sulfate adenylyltransferase (ATP) activity
KFK26_RS16465	COG0529	Catalyzes the synthesis of activated sulfate
KFK26_RS16470	COG0175	sulfate reduction
KFK26_RS16475	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFK26_RS16480	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFK26_RS16485	COG0175	sulfate reduction
KFK26_RS16505	COG0784	Response regulator, receiver
KFK26_RS16505	COG2198	Histidine kinase
KFK26_RS16505	COG2205	protein histidine kinase activity
KFK26_RS16550	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KFK26_RS16555	COG3588	fructose-bisphosphate aldolase
KFK26_RS16560	COG0469	pyruvate kinase activity
KFK26_RS16570	COG0126	phosphoglycerate kinase activity
KFK26_RS16600	COG0753	catalase activity
KFK26_RS16620	COG2207	Transcriptional regulator
KFK26_RS16620	COG1917	Cupin 2, conserved barrel domain protein
KFK26_RS16640	COG1506	peptidase
KFK26_RS16640	COG0823	Involved in the tonB-independent uptake of proteins
KFK26_RS16660	COG1297	OPT oligopeptide transporter protein
KFK26_RS16675	COG0587	DNA-directed DNA polymerase activity
KFK26_RS16760	COG0732	type I restriction modification DNA specificity domain
KFK26_RS16795	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
KFK26_RS16935	COG3179	chitinase
KFK26_RS17005	COG1741	Belongs to the pirin family
KFK26_RS17010	COG1966	Carbon starvation protein
KFK26_RS17015	COG2879	small protein
KFK26_RS17050	COG2203	Gaf domain
KFK26_RS17050	COG3706	GGDEF domain
KFK26_RS17050	COG4251	negative regulation of phosphorylation
KFK26_RS17050	COG5001	Diguanylate cyclase
KFK26_RS17055	COG0629	single-stranded DNA binding
KFK26_RS17060	COG0142	geranyltranstransferase activity
KFK26_RS17085	COG0527	aspartate kinase activity
KFK26_RS17095	COG0384	phenazine biosynthesis protein PhzF
KFK26_RS17105	COG1764	response to oxidative stress
KFK26_RS17120	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KFK26_RS17125	COG1678	Uncharacterized ACR, COG1678
KFK26_RS17140	COG0519	Catalyzes the synthesis of GMP from XMP
KFK26_RS17170	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KFK26_RS17230	COG1959	2 iron, 2 sulfur cluster binding
KFK26_RS17235	COG0719	Fe-S assembly protein
KFK26_RS17240	COG0396	ATPase activity
KFK26_RS17245	COG0719	Fe-S assembly protein
KFK26_RS17250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KFK26_RS17260	COG2146	nitrite reductase [NAD(P)H] activity
KFK26_RS17295	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KFK26_RS17310	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KFK26_RS17320	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KFK26_RS17325	COG0174	glutamine synthetase
KFK26_RS17355	COG0326	Molecular chaperone. Has ATPase activity
KFK26_RS17360	COG2207	Transcriptional regulator
KFK26_RS17385	COG0657	acetylesterase activity
KFK26_RS17385	COG2755	lipolytic protein G-D-S-L family
KFK26_RS17410	COG0488	(ABC) transporter
KFK26_RS17445	COG4651	solute:proton antiporter activity
KFK26_RS17445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KFK26_RS17460	COG4772	TonB-dependent receptor
KFK26_RS17470	COG4264	IucA IucC family
KFK26_RS17475	COG2814	Major facilitator Superfamily
KFK26_RS17485	COG0019	diaminopimelate decarboxylase activity
KFK26_RS17505	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KFK26_RS17550	COG4206	TonB-dependent receptor
KFK26_RS17585	COG0542	response to heat
KFK26_RS17620	COG0534	Mate efflux family protein
KFK26_RS17635	COG0336	Belongs to the RNA methyltransferase TrmD family
KFK26_RS17640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KFK26_RS17645	COG0228	four-way junction DNA binding
KFK26_RS17665	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KFK26_RS17675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KFK26_RS17715	COG1555	photosystem II stabilization
KFK26_RS17720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFK26_RS17735	COG3178	'Phosphotransferase
KFK26_RS17740	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KFK26_RS17750	COG0628	permease
KFK26_RS17760	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KFK26_RS17775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KFK26_RS17795	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KFK26_RS17800	COG0271	Belongs to the BolA IbaG family
KFK26_RS17810	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KFK26_RS17820	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KFK26_RS17825	COG1137	ATPase activity
KFK26_RS17840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFK26_RS17845	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KFK26_RS17850	COG1660	Displays ATPase and GTPase activities
KFK26_RS17860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFK26_RS17865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFK26_RS17870	COG2239	Acts as a magnesium transporter
KFK26_RS17880	COG1294	oxidase, subunit
KFK26_RS17885	COG1271	oxidase subunit
KFK26_RS17900	COG1113	amino acid transport
KFK26_RS17915	COG2197	response regulator
KFK26_RS17920	COG0531	amino acid
KFK26_RS17980	COG0754	glutathionylspermidine amidase activity
KFK26_RS18005	COG1842	Phage shock protein A
KFK26_RS18020	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KFK26_RS18025	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KFK26_RS18035	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KFK26_RS18070	COG2201	protein-glutamate methylesterase activity
KFK26_RS18115	COG2201	protein-glutamate methylesterase activity
KFK26_RS18135	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KFK26_RS18180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFK26_RS18185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFK26_RS18215	COG3039	Transposase
KFK26_RS18230	COG0745	RESPONSE REGULATOR receiver
KFK26_RS18235	COG3039	Transposase
KFK26_RS18240	COG2205	protein histidine kinase activity
KFK26_RS18260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KFK26_RS18300	COG3453	Protein conserved in bacteria
KFK26_RS18300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFK26_RS18305	COG0725	ABC transporter, periplasmic molybdate-binding protein
KFK26_RS18310	COG4149	molybdate abc transporter
KFK26_RS18315	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KFK26_RS18335	COG0642	Histidine kinase
KFK26_RS18350	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_RS18360	COG1022	Amp-dependent synthetase and ligase
KFK26_RS18385	COG1376	ErfK ybiS ycfS ynhG family protein
KFK26_RS18390	COG0739	heme binding
KFK26_RS18400	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KFK26_RS18405	COG1301	dicarboxylic acid transport
KFK26_RS18425	COG2304	oxidoreductase activity
KFK26_RS18445	COG0714	Associated with various cellular activities
KFK26_RS18485	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KFK26_RS18510	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KFK26_RS18520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFK26_RS18545	COG1561	YicC-like family, N-terminal region
KFK26_RS18550	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KFK26_RS18565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFK26_RS18600	COG0006	proline dipeptidase activity
KFK26_RS18625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KFK26_RS18635	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KFK26_RS18645	COG2912	Transglutaminase-like superfamily
KFK26_RS18650	COG1773	rubredoxin
KFK26_RS18655	COG0352	thiamine-phosphate diphosphorylase activity
KFK26_RS18680	COG0280	phosphate acetyltransferase
KFK26_RS18680	COG0281	malic enzyme
KFK26_RS18700	COG4191	Histidine kinase
KFK26_RS18715	COG0583	DNA-binding transcription factor activity
KFK26_RS18735	COG2197	response regulator
KFK26_RS18745	COG0642	Histidine kinase
KFK26_RS18760	COG2851	Citrate transporter
KFK26_RS18765	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_RS18770	COG1609	Transcriptional regulator
KFK26_RS18780	COG2211	Major facilitator Superfamily
KFK26_RS18805	COG1162	GTPase activity
KFK26_RS18830	COG0726	polysaccharide deacetylase
KFK26_RS18835	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KFK26_RS18880	COG0242	peptide deformylase activity
KFK26_RS18900	COG0714	Associated with various cellular activities
KFK26_RS18920	COG0537	adenosine 5'-monophosphoramidase activity
KFK26_RS18950	COG0314	molybdopterin synthase activity
KFK26_RS18955	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KFK26_RS18960	COG0315	cyclic pyranopterin monophosphate synthase activity
KFK26_RS18970	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KFK26_RS18975	COG1234	tRNA 3'-trailer cleavage
KFK26_RS18980	COG3642	lipopolysaccharide core region biosynthetic process
KFK26_RS18985	COG0859	PFAM glycosyl transferase family 9
KFK26_RS18995	COG0582	viral genome integration into host DNA
KFK26_RS19070	COG0631	protein serine/threonine phosphatase activity
KFK26_RS19105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFK26_RS19135	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KFK26_RS19145	COG0544	peptidyl-prolyl cis-trans isomerase activity
KFK26_RS19195	COG0473	3-isopropylmalate dehydrogenase activity
KFK26_RS19220	COG4783	chaperone-mediated protein folding
KFK26_RS19235	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KFK26_RS19245	COG0438	transferase activity, transferring glycosyl groups
KFK26_RS19250	COG0671	phosphoesterase, PA-phosphatase related
KFK26_RS19255	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFK26_RS19275	COG2833	Protein of unknown function (DUF455)
KFK26_RS19295	COG0285	dihydrofolate synthase activity
KFK26_RS19305	COG0406	alpha-ribazole phosphatase activity
KFK26_RS19335	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KFK26_RS19340	COG4208	sulfate ABC transporter
KFK26_RS19345	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KFK26_RS19350	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KFK26_RS19355	COG0156	8-amino-7-oxononanoate synthase activity
KFK26_RS19380	COG0604	alcohol dehydrogenase
KFK26_RS19385	COG1902	pentaerythritol trinitrate reductase activity
KFK26_RS19385	COG0446	pyridine nucleotide-disulphide oxidoreductase
KFK26_RS19420	COG0584	glycerophosphoryl diester phosphodiesterase
KFK26_RS19445	COG3039	Transposase
KFK26_RS19460	COG0625	glutathione transferase activity
KFK26_RS19465	COG0039	L-malate dehydrogenase activity
KFK26_RS19470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KFK26_RS19475	COG1217	gtp-binding protein TYPA
KFK26_RS19495	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KFK26_RS19640	COG3781	membrane
KFK26_RS19650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFK26_RS19680	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KFK26_RS19700	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KFK26_RS19725	COG3710	Transcriptional regulator
KFK26_RS19730	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KFK26_RS19740	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KFK26_RS19770	COG2226	methyltransferase
KFK26_RS19775	COG0066	3-isopropylmalate dehydratase activity
KFK26_RS19780	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KFK26_RS19810	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KFK26_RS19815	COG1538	Outer membrane efflux protein
KFK26_RS19820	COG1519	Transferase
KFK26_RS19825	COG1560	Kdo2-lipid A biosynthetic process
KFK26_RS19875	COG0308	aminopeptidase N
KFK26_RS19880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KFK26_RS19890	COG0330	HflC and HflK could
KFK26_RS19895	COG0330	HflC and HflK could
KFK26_RS19915	COG0678	peroxiredoxin activity
KFK26_RS19925	COG2826	transposase and inactivated derivatives, IS30 family
KFK26_RS20030	COG3829	transcription factor binding
KFK26_RS20065	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KFK26_RS20070	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFK26_RS20080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFK26_RS20085	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_RS20110	COG1399	metal-binding, possibly nucleic acid-binding protein
KFK26_RS20150	COG1518	maintenance of DNA repeat elements
KFK26_RS20155	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KFK26_RS20200	COG2188	Transcriptional regulator
KFK26_RS20215	COG1450	Type ii and iii secretion system protein
KFK26_RS20230	COG3166	PFAM Fimbrial assembly family protein
KFK26_RS20235	COG3156	type II secretion system protein K
KFK26_RS20240	COG4795	General secretion pathway protein
KFK26_RS20245	COG2165	general secretion pathway protein
KFK26_RS20250	COG4970	Tfp pilus assembly protein FimT
KFK26_RS20255	COG2165	general secretion pathway protein
KFK26_RS20260	COG1459	type II secretion system
KFK26_RS20270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFK26_RS20280	COG5295	Hep Hag repeat protein
KFK26_RS20285	COG0047	phosphoribosylformylglycinamidine synthase activity
KFK26_RS20285	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KFK26_RS20290	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KFK26_RS20295	COG4974	Belongs to the 'phage' integrase family
KFK26_RS20310	COG0795	lipopolysaccharide-transporting ATPase activity
KFK26_RS20320	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFK26_RS20335	COG0525	valine-tRNA ligase activity
KFK26_RS20365	COG3039	Transposase
KFK26_RS20390	COG3039	Transposase
KFK26_RS20420	COG1183	phosphatidylcholine synthase activity
KFK26_RS20430	COG0442	prolyl-tRNA aminoacylation
KFK26_RS20445	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFK26_RS20450	COG1127	ABC transporter
KFK26_RS20455	COG3218	ABC-type transport auxiliary lipoprotein component
KFK26_RS20455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KFK26_RS20490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFK26_RS20495	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KFK26_RS20495	COG0662	Cupin 2, conserved barrel domain protein
KFK26_RS20520	COG2086	electron transfer activity
KFK26_RS20545	COG3328	transposase activity
KFK26_RS20585	COG0626	cystathionine gamma-synthase activity
KFK26_RS20615	COG0625	glutathione transferase activity
KFK26_RS20625	COG0513	Belongs to the DEAD box helicase family
KFK26_RS20630	COG0720	synthase
KFK26_RS20640	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KFK26_RS20645	COG1956	GAF domain-containing protein
KFK26_RS20680	COG0339	signal peptide processing
KFK26_RS20730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFK26_RS20735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFK26_RS20785	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KFK26_RS20790	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KFK26_RS20795	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KFK26_RS20800	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KFK26_RS20805	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KFK26_RS20810	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KFK26_RS20820	COG0356	it plays a direct role in the translocation of protons across the membrane
KFK26_RS20840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFK26_RS20850	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFK26_RS20880	COG2011	ABC-type metal ion transport system permease component
KFK26_RS20890	COG0697	spore germination
KFK26_RS20925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KFK26_RS20930	COG1187	pseudouridine synthase activity
KFK26_RS20935	COG2813	Specifically methylates the guanine in position
KFK26_RS20965	COG2205	protein histidine kinase activity
KFK26_RS20965	COG2202	Pas domain
KFK26_RS20990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFK26_RS21040	COG0745	RESPONSE REGULATOR receiver
KFK26_RS21055	COG1404	Belongs to the peptidase S8 family
KFK26_RS21070	COG0842	Transport permease protein
KFK26_RS21075	COG1131	(ABC) transporter
KFK26_RS21080	COG0025	NhaP-type Na H and K H
KFK26_RS21090	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KFK26_RS21100	COG1573	uracil-dna glycosylase
KFK26_RS21110	COG3384	dioxygenase
KFK26_RS21125	COG0667	Aldo Keto reductase
KFK26_RS21135	COG3590	peptidase
KFK26_RS21155	COG0531	amino acid
KFK26_RS21220	COG1271	oxidase subunit
KFK26_RS21260	COG1324	tolerance protein
KFK26_RS21270	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KFK26_RS21275	COG0511	ligase activity, forming carbon-carbon bonds
KFK26_RS21285	COG0439	Biotin carboxylase
KFK26_RS21325	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KFK26_RS21450	COG3210	domain, Protein
KFK26_RS21455	COG2831	hemolysin activation secretion protein
KFK26_RS21495	COG0138	bifunctional purine biosynthesis protein purh
KFK26_RS21505	COG0151	Belongs to the GarS family
KFK26_RS21510	COG1136	(ABC) transporter
KFK26_RS21510	COG0577	efflux transmembrane transporter activity
KFK26_RS21520	COG1289	transmembrane transporter activity
KFK26_RS21535	COG2814	Major facilitator Superfamily
KFK26_RS21550	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KFK26_RS21585	COG0745	RESPONSE REGULATOR receiver
KFK26_RS21630	COG0739	heme binding
KFK26_RS21645	COG2211	Major facilitator Superfamily
KFK26_RS21650	COG0708	Exodeoxyribonuclease III
KFK26_RS21665	COG1192	Involved in chromosome partitioning
KFK26_RS21670	COG1475	DNA binding
KFK26_RS21685	COG0463	Glycosyl transferase, family 2
KFK26_RS21705	COG0756	dUTP diphosphatase activity
KFK26_RS21710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KFK26_RS21715	COG2003	Belongs to the UPF0758 family
KFK26_RS21720	COG0018	arginyl-trna synthetase
KFK26_RS21735	COG4221	oxidoreductase activity
KFK26_RS21760	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KFK26_RS21765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFK26_RS21780	COG3485	protocatechuate 3,4-dioxygenase
KFK26_RS21785	COG3485	protocatechuate 3,4-dioxygenase
KFK26_RS21825	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFK26_RS21830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFK26_RS21840	COG0045	succinate-CoA ligase (ADP-forming) activity
KFK26_RS21840	COG1042	CoA-binding domain protein
KFK26_RS21840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KFK26_RS21850	COG2239	Acts as a magnesium transporter
KFK26_RS21865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFK26_RS21870	COG3387	PFAM Glycoside hydrolase 15-related
KFK26_RS21885	COG3100	YcgL domain-containing protein
KFK26_RS21890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KFK26_RS21900	COG0463	Glycosyl transferase, family 2
KFK26_RS21915	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_RS21925	COG0156	8-amino-7-oxononanoate synthase activity
KFK26_RS21930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KFK26_RS21935	COG1040	competence protein
KFK26_RS21940	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KFK26_RS21950	COG0628	permease
KFK26_RS21960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFK26_RS21970	COG1595	DNA-templated transcription, initiation
KFK26_RS21975	COG0753	catalase activity
KFK26_RS22020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFK26_RS22025	COG0180	Tryptophanyl-tRNA synthetase
KFK26_RS22030	COG3237	CsbD-like
KFK26_RS22065	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KFK26_RS22080	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KFK26_RS22085	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KFK26_RS22085	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KFK26_RS22095	COG3228	Belongs to the MtfA family
KFK26_RS22125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFK26_RS22160	COG1199	ATP-dependent helicase activity
KFK26_RS22200	COG0583	DNA-binding transcription factor activity
KFK26_RS22245	COG0625	glutathione transferase activity
KFK26_RS22280	COG4555	ABC transporter
KFK26_RS22290	COG1476	TRANSCRIPTIONal
KFK26_RS22315	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFK26_RS22320	COG1131	(ABC) transporter
KFK26_RS22325	COG0842	Transport permease protein
KFK26_RS22335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KFK26_RS22400	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFK26_RS22410	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KFK26_RS22420	COG0564	pseudouridine synthase activity
KFK26_RS22450	COG0339	signal peptide processing
KFK26_RS22480	COG3254	rhamnose metabolic process
KFK26_RS22485	COG0738	Major facilitator superfamily
KFK26_RS22490	COG1414	Transcriptional regulator
KFK26_RS22505	COG2205	protein histidine kinase activity
KFK26_RS22515	COG3459	Glycosyltransferase 36 associated
KFK26_RS22520	COG2211	Major facilitator Superfamily
KFK26_RS22525	COG3265	gluconokinase activity
KFK26_RS22530	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFK26_RS22600	COG1127	ABC transporter
KFK26_RS22605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFK26_RS22610	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KFK26_RS22625	COG2853	Lipoprotein
KFK26_RS22650	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KFK26_RS22715	COG0676	glucose-6-phosphate 1-epimerase activity
KFK26_RS22740	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFK26_RS22750	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFK26_RS22760	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFK26_RS22765	COG1064	alcohol dehydrogenase
KFK26_RS22805	COG1522	sequence-specific DNA binding
KFK26_RS22810	COG3186	Phenylalanine-4-hydroxylase
KFK26_RS22845	COG0656	L-ascorbic acid biosynthetic process
KFK26_RS22850	COG2130	NADP-dependent
KFK26_RS22855	COG0667	Aldo Keto reductase
KFK26_RS22865	COG1187	pseudouridine synthase activity
KFK26_RS22880	COG1643	Atp-dependent helicase
KFK26_RS22885	COG4807	Protein conserved in bacteria
KFK26_RS22890	COG4948	Mandelate Racemase Muconate Lactonizing
KFK26_RS22895	COG0179	Fumarylacetoacetate (FAA) hydrolase
KFK26_RS22900	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_RS22960	COG3162	membrane
KFK26_RS22965	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFK26_RS22980	COG0708	Exodeoxyribonuclease III
KFK26_RS22995	COG2091	lysine biosynthetic process via aminoadipic acid
KFK26_RS23005	COG3540	Alkaline phosphatase
KFK26_RS23010	COG0357	Ribosomal RNA small subunit methyltransferase G
KFK26_RS23025	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KFK26_RS23030	COG2159	amidohydrolase
KFK26_RS23040	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KFK26_RS23045	COG0583	DNA-binding transcription factor activity
KFK26_RS23050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFK26_RS23065	COG0210	DNA helicase
KFK26_RS23085	COG0531	amino acid
KFK26_RS23095	COG1322	Protein conserved in bacteria
KFK26_RS23105	COG0386	Belongs to the glutathione peroxidase family
KFK26_RS23155	COG0793	Belongs to the peptidase S41A family
KFK26_RS23160	COG4942	peptidase
KFK26_RS23170	COG2234	aminopeptidase activity
KFK26_RS23215	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFK26_RS23220	COG0302	gtp cyclohydrolase
KFK26_RS23240	COG0477	Major facilitator Superfamily
KFK26_RS23365	COG1929	Belongs to the glycerate kinase type-1 family
KFK26_RS23370	COG2271	Major facilitator Superfamily
KFK26_RS23385	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KFK26_RS23390	COG0861	Integral membrane protein TerC family
KFK26_RS23400	COG0584	glycerophosphoryl diester phosphodiesterase
KFK26_RS23410	COG0671	phosphoesterase, PA-phosphatase related
KFK26_RS23415	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KFK26_RS23420	COG0726	polysaccharide deacetylase
KFK26_RS23425	COG0706	membrane insertase activity
KFK26_RS23445	COG1116	anion transmembrane transporter activity
