locus-tag	class	description
EYR27_RS00010	COG2890	protein-(glutamine-N5) methyltransferase activity
EYR27_RS00045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYR27_RS00045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYR27_RS00060	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EYR27_RS00115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYR27_RS00120	COG1404	Belongs to the peptidase S8 family
EYR27_RS00155	COG1295	ribonuclease BN
EYR27_RS00160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYR27_RS00180	COG0521	Mo-molybdopterin cofactor biosynthetic process
EYR27_RS00190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EYR27_RS00195	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EYR27_RS00205	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EYR27_RS00220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYR27_RS00230	COG0193	aminoacyl-tRNA hydrolase activity
EYR27_RS00235	COG0012	GTP binding
EYR27_RS00265	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EYR27_RS00270	COG0250	Participates in transcription elongation, termination and antitermination
EYR27_RS00280	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EYR27_RS00285	COG0081	regulation of translation
EYR27_RS00290	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EYR27_RS00300	COG0085	RNA polymerase activity
EYR27_RS00305	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EYR27_RS00310	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EYR27_RS00315	COG0049	tRNA binding
EYR27_RS00340	COG0051	transcription antitermination factor activity, RNA binding
EYR27_RS00350	COG0088	Forms part of the polypeptide exit tunnel
EYR27_RS00360	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EYR27_RS00370	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EYR27_RS00380	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EYR27_RS00385	COG0255	Belongs to the universal ribosomal protein uL29 family
EYR27_RS00390	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EYR27_RS00395	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EYR27_RS00400	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EYR27_RS00435	COG1841	ribosomal large subunit assembly
EYR27_RS00440	COG0200	Binds to the 23S rRNA
EYR27_RS00445	COG0201	protein transport
EYR27_RS00470	COG0203	ribosomal protein L17
EYR27_RS00475	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EYR27_RS00485	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EYR27_RS00520	COG1217	gtp-binding protein TYPA
EYR27_RS00525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EYR27_RS00535	COG0625	glutathione transferase activity
EYR27_RS00585	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYR27_RS00585	COG1902	pentaerythritol trinitrate reductase activity
EYR27_RS00620	COG0156	8-amino-7-oxononanoate synthase activity
EYR27_RS00625	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EYR27_RS00630	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EYR27_RS00635	COG4208	sulfate ABC transporter
EYR27_RS00640	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EYR27_RS00675	COG0406	alpha-ribazole phosphatase activity
EYR27_RS00690	COG0285	dihydrofolate synthase activity
EYR27_RS00710	COG2833	Protein of unknown function (DUF455)
EYR27_RS00720	COG3291	Pkd domain containing protein
EYR27_RS00735	COG3039	Transposase
EYR27_RS00760	COG1560	Kdo2-lipid A biosynthetic process
EYR27_RS00765	COG1519	Transferase
EYR27_RS00770	COG1538	Outer membrane efflux protein
EYR27_RS00775	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EYR27_RS00805	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EYR27_RS00810	COG0066	3-isopropylmalate dehydratase activity
EYR27_RS00820	COG0473	3-isopropylmalate dehydrogenase activity
EYR27_RS00845	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EYR27_RS00860	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EYR27_RS00865	COG3710	Transcriptional regulator
EYR27_RS00890	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EYR27_RS00910	COG3039	Transposase
EYR27_RS00930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYR27_RS00940	COG3781	membrane
EYR27_RS00950	COG0671	phosphoesterase, PA-phosphatase related
EYR27_RS00980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYR27_RS00985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYR27_RS01025	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EYR27_RS01035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EYR27_RS01055	COG0352	thiamine-phosphate diphosphorylase activity
EYR27_RS01060	COG1773	rubredoxin
EYR27_RS01065	COG2912	Transglutaminase-like superfamily
EYR27_RS01085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EYR27_RS01110	COG0006	proline dipeptidase activity
EYR27_RS01140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYR27_RS01155	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EYR27_RS01160	COG1561	YicC-like family, N-terminal region
EYR27_RS01180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYR27_RS01190	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EYR27_RS01215	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EYR27_RS01255	COG0714	Associated with various cellular activities
EYR27_RS01275	COG2304	oxidoreductase activity
EYR27_RS01295	COG1301	dicarboxylic acid transport
EYR27_RS01300	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EYR27_RS01315	COG0739	heme binding
EYR27_RS01320	COG1376	ErfK ybiS ycfS ynhG family protein
EYR27_RS01385	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EYR27_RS01390	COG4149	molybdate abc transporter
EYR27_RS01395	COG0725	ABC transporter, periplasmic molybdate-binding protein
EYR27_RS01400	COG3453	Protein conserved in bacteria
EYR27_RS01400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYR27_RS01415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EYR27_RS01450	COG0469	pyruvate kinase activity
EYR27_RS01460	COG3588	fructose-bisphosphate aldolase
EYR27_RS01465	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EYR27_RS01515	COG2198	Histidine kinase
EYR27_RS01515	COG2205	protein histidine kinase activity
EYR27_RS01515	COG0784	Response regulator, receiver
EYR27_RS01535	COG0175	sulfate reduction
EYR27_RS01540	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EYR27_RS01545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYR27_RS01550	COG0175	sulfate reduction
EYR27_RS01555	COG0529	Catalyzes the synthesis of activated sulfate
EYR27_RS01555	COG2895	sulfate adenylyltransferase (ATP) activity
EYR27_RS01565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYR27_RS01570	COG0308	aminopeptidase N
EYR27_RS01585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYR27_RS01600	COG1970	mechanosensitive ion channel activity
EYR27_RS01630	COG0471	metal ion transport
EYR27_RS01630	COG3273	potassium ion transport
EYR27_RS01645	COG2022	thiamine diphosphate biosynthetic process
EYR27_RS01750	COG2003	Belongs to the UPF0758 family
EYR27_RS01810	COG3039	Transposase
EYR27_RS01870	COG2814	Major facilitator Superfamily
EYR27_RS01890	COG3039	Transposase
EYR27_RS01900	COG3039	Transposase
EYR27_RS01950	COG0745	RESPONSE REGULATOR receiver
EYR27_RS02005	COG3039	Transposase
EYR27_RS02035	COG1121	(ABC) transporter
EYR27_RS02045	COG3039	Transposase
EYR27_RS02095	COG0045	succinate-CoA ligase (ADP-forming) activity
EYR27_RS02100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EYR27_RS02115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYR27_RS02115	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EYR27_RS02120	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYR27_RS02125	COG0564	pseudouridine synthase activity
EYR27_RS02140	COG3011	Protein conserved in bacteria
EYR27_RS02145	COG0840	transmembrane signaling receptor activity
EYR27_RS02160	COG3387	PFAM Glycoside hydrolase 15-related
EYR27_RS02165	COG1877	trehalose-phosphatase activity
EYR27_RS02210	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EYR27_RS02225	COG1595	DNA-templated transcription, initiation
EYR27_RS02235	COG1946	Acyl-CoA thioesterase
EYR27_RS02250	COG0824	Thioesterase
EYR27_RS02255	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EYR27_RS02265	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EYR27_RS02270	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EYR27_RS02275	COG0268	Binds directly to 16S ribosomal RNA
EYR27_RS02280	COG0728	peptidoglycan biosynthetic process
EYR27_RS02285	COG0196	riboflavin kinase activity
EYR27_RS02295	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EYR27_RS02300	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EYR27_RS02310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EYR27_RS02315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYR27_RS02320	COG1845	cytochrome c oxidase, subunit III
EYR27_RS02325	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EYR27_RS02345	COG3209	COG3209 Rhs family protein
EYR27_RS02365	COG2826	transposase and inactivated derivatives, IS30 family
EYR27_RS02390	COG2207	Transcriptional regulator
EYR27_RS02395	COG0326	Molecular chaperone. Has ATPase activity
EYR27_RS02405	COG1366	Belongs to the anti-sigma-factor antagonist family
EYR27_RS02410	COG1366	Belongs to the anti-sigma-factor antagonist family
EYR27_RS02415	COG2172	sigma factor antagonist activity
EYR27_RS02445	COG4191	Histidine kinase
EYR27_RS02445	COG0784	Response regulator, receiver
EYR27_RS02535	COG0587	DNA-directed DNA polymerase activity
EYR27_RS02555	COG1297	OPT oligopeptide transporter protein
EYR27_RS02560	COG3039	Transposase
EYR27_RS02585	COG3039	Transposase
EYR27_RS02590	COG1506	peptidase
EYR27_RS02590	COG0823	Involved in the tonB-independent uptake of proteins
EYR27_RS02600	COG1917	Cupin 2, conserved barrel domain protein
EYR27_RS02600	COG2207	Transcriptional regulator
EYR27_RS02645	COG0753	catalase activity
EYR27_RS02720	COG2194	sulfuric ester hydrolase activity
EYR27_RS02730	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EYR27_RS02735	COG0745	RESPONSE REGULATOR receiver
EYR27_RS02740	COG0642	Histidine kinase
EYR27_RS02750	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EYR27_RS02755	COG2894	cell division
EYR27_RS02775	COG4585	Histidine kinase
EYR27_RS02780	COG2197	response regulator
EYR27_RS02795	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EYR27_RS02820	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EYR27_RS02855	COG0542	response to heat
EYR27_RS02880	COG4206	TonB-dependent receptor
EYR27_RS02940	COG0019	diaminopimelate decarboxylase activity
EYR27_RS02950	COG2814	Major facilitator Superfamily
EYR27_RS02955	COG4264	IucA IucC family
EYR27_RS02965	COG4772	TonB-dependent receptor
EYR27_RS02980	COG4651	solute:proton antiporter activity
EYR27_RS02980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EYR27_RS03015	COG0488	(ABC) transporter
EYR27_RS03045	COG1555	photosystem II stabilization
EYR27_RS03070	COG2146	nitrite reductase [NAD(P)H] activity
EYR27_RS03080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EYR27_RS03085	COG0719	Fe-S assembly protein
EYR27_RS03090	COG0396	ATPase activity
EYR27_RS03095	COG0719	Fe-S assembly protein
EYR27_RS03100	COG1959	2 iron, 2 sulfur cluster binding
EYR27_RS03140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EYR27_RS03200	COG3039	Transposase
EYR27_RS03210	COG0519	Catalyzes the synthesis of GMP from XMP
EYR27_RS03220	COG1678	Uncharacterized ACR, COG1678
EYR27_RS03225	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EYR27_RS03240	COG1764	response to oxidative stress
EYR27_RS03250	COG0384	phenazine biosynthesis protein PhzF
EYR27_RS03255	COG0384	phenazine biosynthesis protein PhzF
EYR27_RS03260	COG0527	aspartate kinase activity
EYR27_RS03290	COG0142	geranyltranstransferase activity
EYR27_RS03295	COG0629	single-stranded DNA binding
EYR27_RS03300	COG3706	GGDEF domain
EYR27_RS03300	COG4251	negative regulation of phosphorylation
EYR27_RS03300	COG5001	Diguanylate cyclase
EYR27_RS03300	COG2203	Gaf domain
EYR27_RS03310	COG2080	2 iron, 2 sulfur cluster binding
EYR27_RS03315	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EYR27_RS03320	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EYR27_RS03325	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EYR27_RS03375	COG2879	small protein
EYR27_RS03380	COG1966	Carbon starvation protein
EYR27_RS03405	COG1966	Carbon starvation protein
EYR27_RS03415	COG1741	Belongs to the pirin family
EYR27_RS03445	COG1741	Belongs to the pirin family
EYR27_RS03450	COG1515	deoxyribonuclease V activity
EYR27_RS03470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYR27_RS03480	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EYR27_RS03485	COG2199	diguanylate cyclase activity
EYR27_RS03485	COG2202	Pas domain
EYR27_RS03485	COG2200	EAL domain
EYR27_RS03490	COG0835	chemotaxis
EYR27_RS03495	COG0840	transmembrane signaling receptor activity
EYR27_RS03500	COG0643	Histidine kinase
EYR27_RS03500	COG2198	Histidine kinase
EYR27_RS03510	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EYR27_RS03520	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EYR27_RS03555	COG3039	Transposase
EYR27_RS03580	COG3039	Transposase
EYR27_RS03600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYR27_RS03605	COG0735	belongs to the Fur family
EYR27_RS03620	COG2207	Transcriptional regulator
EYR27_RS03705	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EYR27_RS03755	COG5001	Diguanylate cyclase
EYR27_RS03755	COG5002	protein histidine kinase activity
EYR27_RS03760	COG1187	pseudouridine synthase activity
EYR27_RS03780	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EYR27_RS03790	COG0475	glutathione-regulated potassium exporter activity
EYR27_RS03820	COG1132	(ABC) transporter
EYR27_RS03865	COG2155	Conserved Protein
EYR27_RS03875	COG3118	belongs to the thioredoxin family
EYR27_RS03905	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EYR27_RS03930	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EYR27_RS03950	COG3039	Transposase
EYR27_RS03980	COG2968	Membrane
EYR27_RS03995	COG3164	Protein of unknown function
EYR27_RS04005	COG0312	modulator of DNA gyrase
EYR27_RS04010	COG3028	Belongs to the UPF0307 family
EYR27_RS04015	COG0312	modulator of DNA gyrase
EYR27_RS04030	COG4104	PAAR repeat-containing protein
EYR27_RS04035	COG0142	geranyltranstransferase activity
EYR27_RS04040	COG1722	exodeoxyribonuclease VII activity
EYR27_RS04045	COG0037	tRNA processing
EYR27_RS04050	COG1785	Belongs to the alkaline phosphatase family
EYR27_RS04055	COG1301	dicarboxylic acid transport
EYR27_RS04075	COG0791	NLP P60 protein
EYR27_RS04080	COG0791	NLP P60 protein
EYR27_RS04085	COG1047	Peptidyl-prolyl cis-trans
EYR27_RS04090	COG2311	Membrane
EYR27_RS04095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYR27_RS04125	COG3590	peptidase
EYR27_RS04130	COG3590	peptidase
EYR27_RS04150	COG0489	protein tyrosine kinase activity
EYR27_RS04160	COG0717	Belongs to the dCTP deaminase family
EYR27_RS04185	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYR27_RS04190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYR27_RS04215	COG3039	Transposase
EYR27_RS04235	COG0433	COG0433 Predicted ATPase
EYR27_RS04265	COG2890	protein-(glutamine-N5) methyltransferase activity
EYR27_RS04270	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EYR27_RS04275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYR27_RS04280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EYR27_RS04300	COG0101	tRNA pseudouridine synthase activity
EYR27_RS04305	COG0135	phosphoribosylanthranilate isomerase activity
EYR27_RS04315	COG0133	tryptophan synthase activity
EYR27_RS04330	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EYR27_RS04335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYR27_RS04375	COG0149	triose-phosphate isomerase activity
EYR27_RS04390	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYR27_RS04400	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYR27_RS04405	COG0649	NAD binding
EYR27_RS04410	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EYR27_RS04415	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EYR27_RS04420	COG1034	ATP synthesis coupled electron transport
EYR27_RS04425	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EYR27_RS04455	COG1007	ATP synthesis coupled electron transport
EYR27_RS04465	COG0779	Required for maturation of 30S ribosomal subunits
EYR27_RS04470	COG0195	Participates in both transcription termination and antitermination
EYR27_RS04475	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EYR27_RS04490	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EYR27_RS04495	COG1185	polyribonucleotide nucleotidyltransferase activity
EYR27_RS04530	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EYR27_RS04540	COG2095	MarC family integral membrane protein
EYR27_RS04555	COG1611	Belongs to the LOG family
EYR27_RS04595	COG4969	Belongs to the N-Me-Phe pilin family
EYR27_RS04600	COG0556	nucleotide-excision repair
EYR27_RS04615	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EYR27_RS04630	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EYR27_RS04685	COG0438	transferase activity, transferring glycosyl groups
EYR27_RS04690	COG0438	transferase activity, transferring glycosyl groups
EYR27_RS04700	COG0438	transferase activity, transferring glycosyl groups
EYR27_RS04740	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EYR27_RS04750	COG1960	acyl-CoA dehydrogenase activity
EYR27_RS04760	COG3040	lipid binding
EYR27_RS04780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EYR27_RS04785	COG0784	Response regulator, receiver
EYR27_RS04785	COG4191	Histidine kinase
EYR27_RS04795	COG1194	a g-specific adenine glycosylase
EYR27_RS04805	COG0552	protein localization to endoplasmic reticulum
EYR27_RS04815	COG3938	Belongs to the proline racemase family
EYR27_RS04820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYR27_RS04835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYR27_RS04845	COG0006	proline dipeptidase activity
EYR27_RS04860	COG0531	amino acid
EYR27_RS04995	COG3039	Transposase
EYR27_RS05010	COG3039	Transposase
EYR27_RS05015	COG0326	Molecular chaperone. Has ATPase activity
EYR27_RS05020	COG0742	ribosomal rna small subunit methyltransferase
EYR27_RS05025	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EYR27_RS05040	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EYR27_RS05045	COG0405	Gamma-glutamyltransferase
EYR27_RS05100	COG0343	queuine tRNA-ribosyltransferase activity
EYR27_RS05105	COG1862	Preprotein translocase
EYR27_RS05115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYR27_RS05135	COG0840	transmembrane signaling receptor activity
EYR27_RS05150	COG5002	protein histidine kinase activity
EYR27_RS05150	COG0784	Response regulator, receiver
EYR27_RS05150	COG2205	protein histidine kinase activity
EYR27_RS05155	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EYR27_RS05160	COG4191	Histidine kinase
EYR27_RS05160	COG0784	Response regulator, receiver
EYR27_RS05175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYR27_RS05195	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYR27_RS05210	COG1595	DNA-templated transcription, initiation
EYR27_RS05265	COG2244	polysaccharide biosynthetic process
EYR27_RS05295	COG2264	protein methyltransferase activity
EYR27_RS05305	COG0438	transferase activity, transferring glycosyl groups
EYR27_RS05320	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EYR27_RS05325	COG1132	(ABC) transporter
EYR27_RS05340	COG0477	Major facilitator Superfamily
EYR27_RS05360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYR27_RS05375	COG1253	flavin adenine dinucleotide binding
EYR27_RS05395	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EYR27_RS05415	COG0504	CTP synthase activity
EYR27_RS05420	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EYR27_RS05430	COG0148	phosphopyruvate hydratase activity
EYR27_RS05435	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EYR27_RS05450	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EYR27_RS05465	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EYR27_RS05470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EYR27_RS05475	COG1238	metal cluster binding
EYR27_RS05490	COG1534	Rna-binding protein
EYR27_RS05495	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EYR27_RS05505	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EYR27_RS05520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EYR27_RS05525	COG1546	Belongs to the CinA family
EYR27_RS05540	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EYR27_RS05550	COG2137	regulation of response to DNA damage stimulus
EYR27_RS05555	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EYR27_RS05560	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EYR27_RS05575	COG1741	Belongs to the pirin family
EYR27_RS05580	COG0583	DNA-binding transcription factor activity
EYR27_RS05605	COG0352	thiamine-phosphate diphosphorylase activity
EYR27_RS05605	COG0351	phosphomethylpyrimidine kinase
EYR27_RS05615	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EYR27_RS05620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYR27_RS05635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYR27_RS05645	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EYR27_RS05650	COG3734	2-keto-3-deoxy-galactonokinase
EYR27_RS05660	COG4948	Mandelate Racemase Muconate Lactonizing
EYR27_RS05665	COG0800	Aldolase
EYR27_RS05710	COG1501	Belongs to the glycosyl hydrolase 31 family
EYR27_RS05720	COG1070	Carbohydrate kinase
EYR27_RS05730	COG0477	Major facilitator Superfamily
EYR27_RS05750	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYR27_RS05755	COG1469	GTP cyclohydrolase I activity
EYR27_RS05765	COG0617	tRNA 3'-terminal CCA addition
EYR27_RS05785	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EYR27_RS05815	COG1472	Belongs to the glycosyl hydrolase 3 family
EYR27_RS05835	COG5001	Diguanylate cyclase
EYR27_RS05835	COG2203	Gaf domain
EYR27_RS05835	COG4251	negative regulation of phosphorylation
EYR27_RS05835	COG3706	GGDEF domain
EYR27_RS05845	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYR27_RS05855	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EYR27_RS05870	COG0671	phosphoesterase, PA-phosphatase related
EYR27_RS05890	COG1794	racemase activity, acting on amino acids and derivatives
EYR27_RS05900	COG0697	spore germination
EYR27_RS05905	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EYR27_RS05925	COG1012	belongs to the aldehyde dehydrogenase family
EYR27_RS05950	COG0174	glutamine synthetase
EYR27_RS05955	COG3039	Transposase
EYR27_RS05960	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EYR27_RS05970	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EYR27_RS05985	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EYR27_RS05990	COG3039	Transposase
EYR27_RS06025	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EYR27_RS06040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYR27_RS06050	COG0124	histidyl-tRNA synthetase
EYR27_RS06065	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EYR27_RS06075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EYR27_RS06080	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EYR27_RS06080	COG0131	Imidazoleglycerol-phosphate dehydratase
EYR27_RS06090	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EYR27_RS06100	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EYR27_RS06100	COG0140	phosphoribosyl-ATP diphosphatase activity
EYR27_RS06135	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EYR27_RS06140	COG0235	Class ii aldolase
EYR27_RS06145	COG0531	amino acid
EYR27_RS06150	COG0531	amino acid
EYR27_RS06160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYR27_RS06165	COG0277	FAD linked oxidase domain protein
EYR27_RS06185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EYR27_RS06235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYR27_RS06240	COG2258	MOSC domain
EYR27_RS06245	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EYR27_RS06250	COG0505	Belongs to the CarA family
EYR27_RS06265	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYR27_RS06270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYR27_RS06280	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EYR27_RS06320	COG2198	Histidine kinase
EYR27_RS06320	COG0784	Response regulator, receiver
EYR27_RS06320	COG2205	protein histidine kinase activity
EYR27_RS06325	COG1024	Enoyl-CoA hydratase
EYR27_RS06330	COG0318	PFAM AMP-dependent synthetase and ligase
EYR27_RS06360	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYR27_RS06395	COG0840	transmembrane signaling receptor activity
EYR27_RS06405	COG0835	chemotaxis
EYR27_RS06425	COG0840	transmembrane signaling receptor activity
EYR27_RS06430	COG0840	transmembrane signaling receptor activity
EYR27_RS06435	COG0840	transmembrane signaling receptor activity
EYR27_RS06445	COG0840	transmembrane signaling receptor activity
EYR27_RS06455	COG0840	transmembrane signaling receptor activity
EYR27_RS06460	COG0840	transmembrane signaling receptor activity
EYR27_RS06465	COG0840	transmembrane signaling receptor activity
EYR27_RS06505	COG0840	transmembrane signaling receptor activity
EYR27_RS06520	COG0745	RESPONSE REGULATOR receiver
EYR27_RS06530	COG0835	chemotaxis
EYR27_RS06540	COG1360	Flagellar Motor Protein
EYR27_RS06545	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EYR27_RS06560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYR27_RS06655	COG0784	Response regulator, receiver
EYR27_RS06655	COG0643	Histidine kinase
EYR27_RS06655	COG2198	Histidine kinase
EYR27_RS06720	COG1684	flagellar biosynthetic protein fliR
EYR27_RS06735	COG3190	flagellar
EYR27_RS06785	COG1677	Flagellar hook-basal body complex protein FliE
EYR27_RS06835	COG1028	Short-chain dehydrogenase reductase Sdr
EYR27_RS06845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYR27_RS06865	COG2201	protein-glutamate methylesterase activity
EYR27_RS06895	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EYR27_RS06900	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EYR27_RS06915	COG3951	Flagellar rod assembly protein muramidase FlgJ
EYR27_RS06915	COG1705	Flagellar rod assembly protein muramidase FlgJ
EYR27_RS06920	COG1706	bacterial-type flagellum-dependent cell motility
EYR27_RS06925	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EYR27_RS06940	COG4787	bacterial-type flagellum-dependent cell motility
EYR27_RS06950	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EYR27_RS06955	COG1558	bacterial-type flagellum-dependent cell motility
EYR27_RS06965	COG0835	chemotaxis
EYR27_RS06965	COG0784	Response regulator, receiver
EYR27_RS06985	COG4191	Histidine kinase
EYR27_RS06995	COG4585	Histidine kinase
EYR27_RS07025	COG0482	sulfurtransferase activity
EYR27_RS07040	COG0542	response to heat
EYR27_RS07065	COG0492	ferredoxin-NADP+ reductase activity
EYR27_RS07070	COG1674	ftsk spoiiie
EYR27_RS07095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EYR27_RS07115	COG0038	chloride channel
EYR27_RS07120	COG0183	Belongs to the thiolase family
EYR27_RS07125	COG1024	Enoyl-CoA hydratase
EYR27_RS07125	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYR27_RS07140	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EYR27_RS07160	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYR27_RS07165	COG1160	GTP binding
EYR27_RS07170	COG0303	'Molybdopterin
EYR27_RS07185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EYR27_RS07220	COG0746	molybdenum cofactor guanylyltransferase activity
EYR27_RS07245	COG1648	precorrin-2 dehydrogenase activity
EYR27_RS07245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYR27_RS07300	COG5001	Diguanylate cyclase
EYR27_RS07310	COG4566	intracellular signal transduction
EYR27_RS07375	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EYR27_RS07380	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYR27_RS07380	COG1902	pentaerythritol trinitrate reductase activity
EYR27_RS07395	COG1054	Belongs to the UPF0176 family
EYR27_RS07405	COG1530	ribonuclease E activity
EYR27_RS07415	COG3064	Membrane
EYR27_RS07420	COG0428	transporter
EYR27_RS07425	COG0428	transporter
EYR27_RS07435	COG2154	pterin-4-alpha-carbinolamine dehydratase
EYR27_RS07545	COG0631	protein serine/threonine phosphatase activity
EYR27_RS07550	COG0515	serine threonine protein kinase
EYR27_RS07580	COG1858	cytochrome C peroxidase
EYR27_RS07610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYR27_RS07615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYR27_RS07710	COG2826	transposase and inactivated derivatives, IS30 family
EYR27_RS07725	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EYR27_RS07730	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EYR27_RS07745	COG1024	Enoyl-CoA hydratase
EYR27_RS07755	COG1024	Enoyl-CoA hydratase
EYR27_RS07760	COG1024	Enoyl-CoA hydratase
EYR27_RS07825	COG1304	FMN binding
EYR27_RS07830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EYR27_RS07875	COG0322	excinuclease ABC activity
EYR27_RS07885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYR27_RS07895	COG1663	tetraacyldisaccharide 4'-kinase activity
EYR27_RS07910	COG0811	peptide transport
EYR27_RS07935	COG4591	ABC-type transport system involved in lipoprotein release permease component
EYR27_RS07950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EYR27_RS07965	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EYR27_RS07970	COG2009	succinate dehydrogenase
EYR27_RS07980	COG0354	folic acid binding
EYR27_RS07995	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EYR27_RS08005	COG0363	glucosamine-6-phosphate deaminase activity
EYR27_RS08010	COG0129	dihydroxy-acid dehydratase activity
EYR27_RS08015	COG0800	Aldolase
EYR27_RS08070	COG2826	transposase and inactivated derivatives, IS30 family
EYR27_RS08090	COG2205	protein histidine kinase activity
EYR27_RS08090	COG0784	Response regulator, receiver
EYR27_RS08105	COG2183	response to ionizing radiation
EYR27_RS08115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYR27_RS08115	COG0723	plastoquinol--plastocyanin reductase activity
EYR27_RS08130	COG3243	poly(R)-hydroxyalkanoic acid synthase
EYR27_RS08140	COG1183	phosphatidylcholine synthase activity
EYR27_RS08145	COG1028	Short-chain dehydrogenase reductase Sdr
EYR27_RS08160	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EYR27_RS08170	COG0668	transmembrane transport
EYR27_RS08190	COG1914	H( )-stimulated, divalent metal cation uptake system
EYR27_RS08215	COG0583	DNA-binding transcription factor activity
EYR27_RS08235	COG0583	DNA-binding transcription factor activity
EYR27_RS08240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYR27_RS08245	COG3002	Belongs to the UPF0753 family
EYR27_RS08250	COG0519	Catalyzes the synthesis of GMP from XMP
EYR27_RS08250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYR27_RS08260	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EYR27_RS08275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EYR27_RS08285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYR27_RS08290	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EYR27_RS08300	COG0776	regulation of translation
EYR27_RS08305	COG0539	negative regulation of cytoplasmic translation
EYR27_RS08310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EYR27_RS08325	COG2957	Belongs to the agmatine deiminase family
EYR27_RS08335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYR27_RS08360	COG0395	ABC-type sugar transport system, permease component
EYR27_RS08365	COG1175	transmembrane transport
EYR27_RS08405	COG2350	Protein conserved in bacteria
EYR27_RS08410	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EYR27_RS08415	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EYR27_RS08420	COG1187	pseudouridine synthase activity
EYR27_RS08440	COG0436	Aminotransferase
EYR27_RS08445	COG4133	protoheme IX ABC transporter activity
EYR27_RS08495	COG1278	Cold shock
EYR27_RS08505	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EYR27_RS08510	COG4988	ABC transporter
EYR27_RS08565	COG0165	Argininosuccinate lyase
EYR27_RS08580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYR27_RS08585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYR27_RS08590	COG0137	argininosuccinate synthase activity
EYR27_RS08595	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EYR27_RS08610	COG2166	iron-sulfur cluster assembly
EYR27_RS08635	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EYR27_RS08660	COG4677	pectinesterase activity
EYR27_RS08670	COG3039	Transposase
EYR27_RS08690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EYR27_RS08695	COG0402	S-adenosylhomocysteine deaminase activity
EYR27_RS08710	COG1509	lysine 2,3-aminomutase activity
EYR27_RS08715	COG3300	MHYT domain
EYR27_RS08715	COG5001	Diguanylate cyclase
EYR27_RS08730	COG0483	inositol monophosphate 1-phosphatase activity
EYR27_RS08735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYR27_RS08760	COG0488	(ABC) transporter
EYR27_RS08765	COG0513	Belongs to the DEAD box helicase family
EYR27_RS08770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EYR27_RS08775	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EYR27_RS08800	COG4681	YaeQ
EYR27_RS08805	COG2081	HI0933 family
EYR27_RS08815	COG0501	Belongs to the peptidase M48B family
EYR27_RS08825	COG1028	Short-chain dehydrogenase reductase Sdr
EYR27_RS08850	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EYR27_RS08855	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYR27_RS08860	COG0802	atpase or kinase
EYR27_RS08865	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EYR27_RS08865	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYR27_RS08870	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYR27_RS08890	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYR27_RS08930	COG0582	viral genome integration into host DNA
EYR27_RS08970	COG0835	chemotaxis
EYR27_RS08975	COG0840	transmembrane signaling receptor activity
EYR27_RS08980	COG2094	Belongs to the DNA glycosylase MPG family
EYR27_RS09005	COG2969	positive regulation of protein catabolic process
EYR27_RS09010	COG0625	glutathione transferase activity
EYR27_RS09015	COG2857	Cytochrome c1
EYR27_RS09020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EYR27_RS09025	COG0723	plastoquinol--plastocyanin reductase activity
EYR27_RS09030	COG0741	lytic transglycosylase activity
EYR27_RS09060	COG1702	phosphate starvation-inducible protein PhoH
EYR27_RS09080	COG4535	Mg2 and Co2 transporter CorC
EYR27_RS09095	COG1012	belongs to the aldehyde dehydrogenase family
EYR27_RS09110	COG1177	transmembrane transport
EYR27_RS09115	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYR27_RS09125	COG3842	ATPase activity
EYR27_RS09145	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EYR27_RS09155	COG3039	Transposase
EYR27_RS09160	COG3039	Transposase
EYR27_RS09170	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EYR27_RS09175	COG0174	glutamine synthetase
EYR27_RS09180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYR27_RS09190	COG0477	Major facilitator Superfamily
EYR27_RS09200	COG0243	molybdopterin cofactor binding
EYR27_RS09205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EYR27_RS09210	COG2223	nitrite transmembrane transporter activity
EYR27_RS09220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EYR27_RS09230	COG2733	membrane
EYR27_RS09235	COG0784	Response regulator, receiver
EYR27_RS09235	COG2205	protein histidine kinase activity
EYR27_RS09235	COG5002	protein histidine kinase activity
EYR27_RS09245	COG0708	Exodeoxyribonuclease III
EYR27_RS09300	COG0659	secondary active sulfate transmembrane transporter activity
EYR27_RS09305	COG2902	Dehydrogenase
EYR27_RS09315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYR27_RS09320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYR27_RS09340	COG1609	Transcriptional regulator
EYR27_RS09345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYR27_RS09345	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR27_RS09350	COG1105	Belongs to the carbohydrate kinase PfkB family
EYR27_RS09355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYR27_RS09355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYR27_RS09370	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EYR27_RS09395	COG0583	DNA-binding transcription factor activity
EYR27_RS09425	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EYR27_RS09430	COG0077	Prephenate dehydratase
EYR27_RS09430	COG1605	Chorismate mutase
EYR27_RS09435	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EYR27_RS09440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EYR27_RS09485	COG1228	amidohydrolase
EYR27_RS09490	COG2986	histidine ammonia-lyase
EYR27_RS09500	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EYR27_RS09525	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EYR27_RS09540	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EYR27_RS09545	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EYR27_RS09555	COG3115	cell septum assembly
EYR27_RS09575	COG0360	Binds together with S18 to 16S ribosomal RNA
EYR27_RS09580	COG0316	Belongs to the HesB IscA family
EYR27_RS09615	COG0288	reversible hydration of carbon dioxide
EYR27_RS09630	COG3844	kynureninase activity
EYR27_RS09640	COG2925	Exonuclease
EYR27_RS09650	COG0667	Aldo Keto reductase
EYR27_RS09680	COG0116	Belongs to the methyltransferase superfamily
EYR27_RS09680	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYR27_RS09725	COG0494	nUDIX hydrolase
EYR27_RS09735	COG1024	Enoyl-CoA hydratase
EYR27_RS09745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EYR27_RS09750	COG0659	secondary active sulfate transmembrane transporter activity
EYR27_RS09775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EYR27_RS09780	COG0573	inorganic phosphate transmembrane transporter activity
EYR27_RS09795	COG0704	Plays a role in the regulation of phosphate uptake
EYR27_RS09805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EYR27_RS09815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYR27_RS09830	COG0557	exoribonuclease II activity
EYR27_RS09865	COG1960	acyl-CoA dehydrogenase activity
EYR27_RS09870	COG1960	acyl-CoA dehydrogenase activity
EYR27_RS09875	COG2226	methyltransferase
EYR27_RS09880	COG1410	methionine synthase
EYR27_RS09880	COG0646	methionine synthase
EYR27_RS09885	COG1410	methionine synthase
EYR27_RS09885	COG0646	methionine synthase
EYR27_RS09895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYR27_RS09905	COG1609	Transcriptional regulator
EYR27_RS09920	COG2900	Belongs to the SlyX family
EYR27_RS09935	COG0386	Belongs to the glutathione peroxidase family
EYR27_RS09945	COG1725	Transcriptional regulator
EYR27_RS09950	COG1131	(ABC) transporter
EYR27_RS10015	COG2850	peptidyl-arginine hydroxylation
EYR27_RS10050	COG1132	(ABC) transporter
EYR27_RS10060	COG0583	DNA-binding transcription factor activity
EYR27_RS10080	COG3039	Transposase
EYR27_RS10095	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EYR27_RS10100	COG0484	heat shock protein binding
EYR27_RS10105	COG0443	Heat shock 70 kDa protein
EYR27_RS10110	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EYR27_RS10120	COG0497	DNA recombination
EYR27_RS10130	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYR27_RS10140	COG2914	Belongs to the UPF0125 (RnfH) family
EYR27_RS10150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EYR27_RS10165	COG0582	viral genome integration into host DNA
EYR27_RS10175	COG3039	Transposase
EYR27_RS10180	COG2826	transposase and inactivated derivatives, IS30 family
EYR27_RS10230	COG3706	GGDEF domain
EYR27_RS10250	COG1028	Short-chain dehydrogenase reductase Sdr
EYR27_RS10270	COG0415	Belongs to the DNA photolyase family
EYR27_RS10275	COG0305	Participates in initiation and elongation during chromosome replication
EYR27_RS10285	COG0367	asparagine synthase
EYR27_RS10300	COG1960	acyl-CoA dehydrogenase activity
EYR27_RS10315	COG0084	hydrolase, TatD family'
EYR27_RS10320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EYR27_RS10370	COG3039	Transposase
EYR27_RS10385	COG0840	transmembrane signaling receptor activity
EYR27_RS10400	COG3039	Transposase
EYR27_RS10440	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYR27_RS10455	COG0386	Belongs to the glutathione peroxidase family
EYR27_RS10465	COG0339	signal peptide processing
EYR27_RS10555	COG2814	Major facilitator Superfamily
EYR27_RS10560	COG1566	PFAM secretion protein HlyD family protein
EYR27_RS10575	COG2207	Transcriptional regulator
EYR27_RS10605	COG4774	siderophore transport
EYR27_RS10615	COG0367	asparagine synthase
EYR27_RS10620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYR27_RS10630	COG1393	Belongs to the ArsC family
EYR27_RS10690	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EYR27_RS10705	COG0233	cytoplasmic translational termination
EYR27_RS10715	COG0575	Belongs to the CDS family
EYR27_RS10720	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EYR27_RS10725	COG0750	zinc metalloprotease
EYR27_RS10740	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYR27_RS10745	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYR27_RS10750	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYR27_RS10770	COG0825	malonyl-CoA metabolic process
EYR27_RS10800	COG1981	membrane
EYR27_RS10815	COG3039	Transposase
EYR27_RS10840	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EYR27_RS10855	COG2040	homocysteine
EYR27_RS10860	COG0833	amino acid
EYR27_RS10875	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYR27_RS10875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYR27_RS10885	COG2878	Part of a membrane complex involved in electron transport
EYR27_RS10905	COG1595	DNA-templated transcription, initiation
EYR27_RS10930	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYR27_RS10945	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYR27_RS10950	COG0251	oxidation-reduction process
EYR27_RS10960	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EYR27_RS10960	COG0392	lysyltransferase activity
EYR27_RS11005	COG3039	Transposase
EYR27_RS11010	COG2814	Major facilitator Superfamily
EYR27_RS11015	COG1902	pentaerythritol trinitrate reductase activity
EYR27_RS11035	COG2824	Alkylphosphonate utilization operon protein PhnA
EYR27_RS11045	COG1047	Peptidyl-prolyl cis-trans
EYR27_RS11090	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EYR27_RS11110	COG1451	nucleotide metabolic process
EYR27_RS11130	COG0183	Belongs to the thiolase family
EYR27_RS11160	COG1793	dna ligase
EYR27_RS11160	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EYR27_RS11170	COG1793	dna ligase
EYR27_RS11175	COG1201	RNA secondary structure unwinding
EYR27_RS11195	COG1278	Cold shock
EYR27_RS11200	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EYR27_RS11205	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EYR27_RS11215	COG3046	protein related to deoxyribodipyrimidine photolyase
EYR27_RS11220	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EYR27_RS11225	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EYR27_RS11230	COG2954	triphosphatase activity
EYR27_RS11245	COG1381	Involved in DNA repair and RecF pathway recombination
EYR27_RS11275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYR27_RS11310	COG1024	Enoyl-CoA hydratase
EYR27_RS11315	COG1960	acyl-CoA dehydrogenase activity
EYR27_RS11355	COG3039	Transposase
EYR27_RS11360	COG2801	Transposase and inactivated derivatives
EYR27_RS11385	COG3039	Transposase
EYR27_RS11395	COG3039	Transposase
EYR27_RS11415	COG2353	YceI-like domain
EYR27_RS11430	COG1278	Cold shock
EYR27_RS11440	COG1760	l-serine dehydratase
EYR27_RS11450	COG0527	aspartate kinase activity
EYR27_RS11450	COG0460	homoserine dehydrogenase
EYR27_RS11455	COG0626	cystathionine gamma-synthase activity
EYR27_RS11460	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYR27_RS11465	COG0739	heme binding
EYR27_RS11475	COG1272	protein, Hemolysin III
EYR27_RS11480	COG2982	Protein involved in outer membrane biogenesis
EYR27_RS11490	COG0463	Glycosyl transferase, family 2
EYR27_RS11500	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EYR27_RS11510	COG4771	TonB-dependent receptor
EYR27_RS11515	COG1309	transcriptional regulator
EYR27_RS11525	COG1960	acyl-CoA dehydrogenase activity
EYR27_RS11565	COG0509	glycine decarboxylation via glycine cleavage system
EYR27_RS11580	COG0330	HflC and HflK could
EYR27_RS11595	COG3956	TIGRFAM MazG family protein
EYR27_RS11605	COG0494	nUDIX hydrolase
EYR27_RS11615	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EYR27_RS11620	COG0837	glucose binding
EYR27_RS11635	COG1388	LysM domain
EYR27_RS11635	COG3858	chitin binding
EYR27_RS11655	COG1472	Belongs to the glycosyl hydrolase 3 family
EYR27_RS11705	COG3537	Alpha-1,2-mannosidase
EYR27_RS11760	COG3142	Participates in the control of copper homeostasis
EYR27_RS11765	COG1446	asparaginase
EYR27_RS11775	COG2304	oxidoreductase activity
EYR27_RS11810	COG2201	protein-glutamate methylesterase activity
EYR27_RS11815	COG0643	Histidine kinase
EYR27_RS11815	COG0784	Response regulator, receiver
EYR27_RS11815	COG2198	Histidine kinase
EYR27_RS11820	COG0840	transmembrane signaling receptor activity
EYR27_RS11825	COG0835	chemotaxis
EYR27_RS11840	COG0189	ligase activity
EYR27_RS11860	COG1199	ATP-dependent helicase activity
EYR27_RS11870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYR27_RS11875	COG1215	transferase activity, transferring glycosyl groups
EYR27_RS11885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYR27_RS11900	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
EYR27_RS11940	COG1643	Atp-dependent helicase
EYR27_RS11945	COG0783	Belongs to the Dps family
EYR27_RS11955	COG0514	ATP-dependent DNA helicase (RecQ)
EYR27_RS11975	COG1187	pseudouridine synthase activity
EYR27_RS12015	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EYR27_RS12025	COG0602	queuosine metabolic process
EYR27_RS12035	COG2885	chlorophyll binding
EYR27_RS12040	COG0823	Involved in the tonB-independent uptake of proteins
EYR27_RS12050	COG0848	biopolymer transport protein
EYR27_RS12060	COG0824	Thioesterase
EYR27_RS12065	COG2255	four-way junction helicase activity
EYR27_RS12080	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EYR27_RS12115	COG0477	Major facilitator Superfamily
EYR27_RS12135	COG3039	Transposase
EYR27_RS12140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYR27_RS12150	COG3178	'Phosphotransferase
EYR27_RS12155	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EYR27_RS12165	COG0628	permease
EYR27_RS12175	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EYR27_RS12190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EYR27_RS12215	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYR27_RS12220	COG0271	Belongs to the BolA IbaG family
EYR27_RS12230	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EYR27_RS12240	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EYR27_RS12245	COG1137	ATPase activity
EYR27_RS12260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR27_RS12270	COG1660	Displays ATPase and GTPase activities
EYR27_RS12295	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EYR27_RS12320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR27_RS12325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYR27_RS12335	COG2239	Acts as a magnesium transporter
EYR27_RS12345	COG1294	oxidase, subunit
EYR27_RS12350	COG1271	oxidase subunit
EYR27_RS12360	COG1113	amino acid transport
EYR27_RS12375	COG2197	response regulator
EYR27_RS12380	COG0531	amino acid
EYR27_RS12455	COG0754	glutathionylspermidine amidase activity
EYR27_RS12480	COG1842	Phage shock protein A
EYR27_RS12495	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EYR27_RS12690	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EYR27_RS12700	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EYR27_RS12725	COG0534	Mate efflux family protein
EYR27_RS12740	COG0336	Belongs to the RNA methyltransferase TrmD family
EYR27_RS12745	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EYR27_RS12750	COG0228	four-way junction DNA binding
EYR27_RS12770	COG3039	Transposase
EYR27_RS12785	COG3039	Transposase
EYR27_RS12790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EYR27_RS12800	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYR27_RS12825	COG1304	FMN binding
EYR27_RS12835	COG1657	PFAM Prenyltransferase squalene oxidase
EYR27_RS12840	COG0142	geranyltranstransferase activity
EYR27_RS12845	COG2124	cytochrome p450
EYR27_RS12850	COG1028	Short-chain dehydrogenase reductase Sdr
EYR27_RS12855	COG1141	Ferredoxin
EYR27_RS12860	COG2124	cytochrome p450
EYR27_RS12865	COG2124	cytochrome p450
EYR27_RS12890	COG2826	transposase and inactivated derivatives, IS30 family
EYR27_RS12895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYR27_RS12900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYR27_RS12950	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EYR27_RS13000	COG1309	transcriptional regulator
EYR27_RS13015	COG0308	aminopeptidase N
EYR27_RS13020	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EYR27_RS13035	COG0330	HflC and HflK could
EYR27_RS13040	COG0330	HflC and HflK could
EYR27_RS13065	COG0678	peroxiredoxin activity
EYR27_RS13130	COG3039	Transposase
EYR27_RS13135	COG2828	Protein conserved in bacteria
EYR27_RS13170	COG3829	transcription factor binding
EYR27_RS13210	COG0280	phosphate acetyltransferase
EYR27_RS13210	COG0281	malic enzyme
EYR27_RS13230	COG4191	Histidine kinase
EYR27_RS13245	COG0583	DNA-binding transcription factor activity
EYR27_RS13260	COG2197	response regulator
EYR27_RS13270	COG0642	Histidine kinase
EYR27_RS13290	COG2851	Citrate transporter
EYR27_RS13295	COG1028	Short-chain dehydrogenase reductase Sdr
EYR27_RS13300	COG1609	Transcriptional regulator
EYR27_RS13310	COG2211	Major facilitator Superfamily
EYR27_RS13330	COG3039	Transposase
EYR27_RS13345	COG0436	Aminotransferase
EYR27_RS13410	COG3039	Transposase
EYR27_RS13415	COG3039	Transposase
EYR27_RS13430	COG3039	Transposase
EYR27_RS13455	COG2826	transposase and inactivated derivatives, IS30 family
EYR27_RS13475	COG0631	protein serine/threonine phosphatase activity
EYR27_RS13485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EYR27_RS13515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYR27_RS13555	COG0544	peptidyl-prolyl cis-trans isomerase activity
EYR27_RS13620	COG0473	3-isopropylmalate dehydrogenase activity
EYR27_RS13635	COG4783	chaperone-mediated protein folding
EYR27_RS13650	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EYR27_RS13670	COG0438	transferase activity, transferring glycosyl groups
EYR27_RS13675	COG0671	phosphoesterase, PA-phosphatase related
EYR27_RS13685	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYR27_RS13750	COG3039	Transposase
EYR27_RS13795	COG2353	YceI-like domain
EYR27_RS13825	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EYR27_RS13840	COG3386	PFAM SMP-30 Gluconolaconase
EYR27_RS13855	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EYR27_RS13860	COG3550	peptidyl-serine autophosphorylation
EYR27_RS13870	COG2826	transposase and inactivated derivatives, IS30 family
EYR27_RS13880	COG0459	protein refolding
EYR27_RS13900	COG1324	tolerance protein
EYR27_RS13915	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EYR27_RS13920	COG0511	ligase activity, forming carbon-carbon bonds
EYR27_RS13930	COG0439	Biotin carboxylase
EYR27_RS13980	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EYR27_RS14015	COG0138	bifunctional purine biosynthesis protein purh
EYR27_RS14020	COG0151	Belongs to the GarS family
EYR27_RS14025	COG1289	transmembrane transporter activity
EYR27_RS14030	COG2814	Major facilitator Superfamily
EYR27_RS14040	COG2814	Major facilitator Superfamily
EYR27_RS14060	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EYR27_RS14105	COG0745	RESPONSE REGULATOR receiver
EYR27_RS14140	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EYR27_RS14150	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EYR27_RS14160	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EYR27_RS14165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYR27_RS14175	COG0134	indole-3-glycerol-phosphate synthase activity
EYR27_RS14180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYR27_RS14220	COG0456	acetyltransferase
EYR27_RS14230	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EYR27_RS14250	COG3039	Transposase
EYR27_RS14280	COG2111	Na H antiporter
EYR27_RS14280	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYR27_RS14285	COG1006	Multisubunit Na H antiporter MnhC subunit
EYR27_RS14290	COG0651	ATP synthesis coupled electron transport
EYR27_RS14300	COG2212	antiporter activity
EYR27_RS14305	COG1320	monovalent cation:proton antiporter activity
EYR27_RS14315	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EYR27_RS14340	COG3104	oligopeptide transport
EYR27_RS14345	COG3483	tryptophan 2,3-dioxygenase activity
EYR27_RS14355	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EYR27_RS14370	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYR27_RS14390	COG0513	Belongs to the DEAD box helicase family
EYR27_RS14425	COG3328	transposase activity
EYR27_RS14450	COG2826	transposase and inactivated derivatives, IS30 family
EYR27_RS14455	COG1607	acyl-coa hydrolase
EYR27_RS14465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYR27_RS14480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYR27_RS14490	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYR27_RS14505	COG0045	succinate-CoA ligase (ADP-forming) activity
EYR27_RS14505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYR27_RS14505	COG1042	CoA-binding domain protein
EYR27_RS14515	COG2239	Acts as a magnesium transporter
EYR27_RS14535	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EYR27_RS14540	COG3387	PFAM Glycoside hydrolase 15-related
EYR27_RS14555	COG3100	YcgL domain-containing protein
EYR27_RS14560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYR27_RS14570	COG0463	Glycosyl transferase, family 2
EYR27_RS14590	COG1028	Short-chain dehydrogenase reductase Sdr
EYR27_RS14630	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYR27_RS14645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYR27_RS14715	COG0408	coproporphyrinogen oxidase activity
EYR27_RS14800	COG0210	DNA helicase
EYR27_RS14815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYR27_RS14820	COG0583	DNA-binding transcription factor activity
EYR27_RS14825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EYR27_RS14840	COG2159	amidohydrolase
EYR27_RS14875	COG0357	Ribosomal RNA small subunit methyltransferase G
EYR27_RS14880	COG3540	Alkaline phosphatase
EYR27_RS14890	COG2091	lysine biosynthetic process via aminoadipic acid
EYR27_RS14905	COG0708	Exodeoxyribonuclease III
EYR27_RS14925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYR27_RS14930	COG3162	membrane
EYR27_RS14980	COG2205	protein histidine kinase activity
EYR27_RS14990	COG3459	Glycosyltransferase 36 associated
EYR27_RS14995	COG2211	Major facilitator Superfamily
EYR27_RS15000	COG3265	gluconokinase activity
EYR27_RS15010	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYR27_RS15035	COG2911	Protein conserved in bacteria
EYR27_RS15040	COG0729	surface antigen
EYR27_RS15045	COG4771	TonB-dependent receptor
EYR27_RS15050	COG0457	Tetratricopeptide repeat
EYR27_RS15060	COG0752	glycyl-tRNA synthetase alpha subunit
EYR27_RS15065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EYR27_RS15080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYR27_RS15080	COG0519	Catalyzes the synthesis of GMP from XMP
EYR27_RS15090	COG0805	protein transport
EYR27_RS15095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYR27_RS15100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYR27_RS15110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EYR27_RS15140	COG2974	May be involved in recombination
EYR27_RS15145	COG0037	tRNA processing
EYR27_RS15165	COG3661	Belongs to the glycosyl hydrolase 67 family
EYR27_RS15175	COG4948	Mandelate Racemase Muconate Lactonizing
EYR27_RS15185	COG1472	Belongs to the glycosyl hydrolase 3 family
EYR27_RS15190	COG0246	Mannitol dehydrogenase
EYR27_RS15220	COG2826	transposase and inactivated derivatives, IS30 family
EYR27_RS15250	COG3693	PFAM glycoside hydrolase, family 10
EYR27_RS15275	COG2211	Major facilitator Superfamily
EYR27_RS15330	COG2937	Belongs to the GPAT DAPAT family
EYR27_RS15360	COG0284	orotidine-5'-phosphate decarboxylase activity
EYR27_RS15365	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EYR27_RS15370	COG3132	Protein of unknown function, DUF480
EYR27_RS15385	COG3039	Transposase
EYR27_RS15405	COG2194	sulfuric ester hydrolase activity
EYR27_RS15420	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EYR27_RS15425	COG0237	dephospho-CoA kinase activity
EYR27_RS15450	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EYR27_RS15455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EYR27_RS15465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYR27_RS15470	COG1028	Short-chain dehydrogenase reductase Sdr
EYR27_RS15495	COG1399	metal-binding, possibly nucleic acid-binding protein
EYR27_RS15515	COG3039	Transposase
EYR27_RS15525	COG0714	Associated with various cellular activities
EYR27_RS15545	COG0537	adenosine 5'-monophosphoramidase activity
EYR27_RS15555	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EYR27_RS15575	COG0314	molybdopterin synthase activity
EYR27_RS15580	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EYR27_RS15585	COG0315	cyclic pyranopterin monophosphate synthase activity
EYR27_RS15595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EYR27_RS15600	COG1234	tRNA 3'-trailer cleavage
EYR27_RS15605	COG3642	lipopolysaccharide core region biosynthetic process
EYR27_RS15610	COG0859	PFAM glycosyl transferase family 9
EYR27_RS15640	COG0726	polysaccharide deacetylase
EYR27_RS15645	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EYR27_RS15650	COG3039	Transposase
EYR27_RS15725	COG0242	peptide deformylase activity
EYR27_RS15755	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EYR27_RS15810	COG2188	Transcriptional regulator
EYR27_RS15820	COG1450	Type ii and iii secretion system protein
EYR27_RS15835	COG3166	PFAM Fimbrial assembly family protein
EYR27_RS15840	COG3156	type II secretion system protein K
EYR27_RS15845	COG4795	General secretion pathway protein
EYR27_RS15850	COG2165	general secretion pathway protein
EYR27_RS15855	COG4970	Tfp pilus assembly protein FimT
EYR27_RS15860	COG2165	general secretion pathway protein
EYR27_RS15865	COG1459	type II secretion system
EYR27_RS15875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EYR27_RS15880	COG1404	Belongs to the peptidase S8 family
EYR27_RS15885	COG5295	Hep Hag repeat protein
EYR27_RS15895	COG0047	phosphoribosylformylglycinamidine synthase activity
EYR27_RS15895	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EYR27_RS15905	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EYR27_RS15910	COG4974	Belongs to the 'phage' integrase family
EYR27_RS15925	COG3039	Transposase
EYR27_RS15930	COG0795	lipopolysaccharide-transporting ATPase activity
EYR27_RS15940	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EYR27_RS15955	COG0525	valine-tRNA ligase activity
EYR27_RS15985	COG1183	phosphatidylcholine synthase activity
EYR27_RS15995	COG0442	prolyl-tRNA aminoacylation
EYR27_RS16010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EYR27_RS16015	COG1127	ABC transporter
EYR27_RS16020	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EYR27_RS16020	COG3218	ABC-type transport auxiliary lipoprotein component
EYR27_RS16060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYR27_RS16065	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EYR27_RS16065	COG0662	Cupin 2, conserved barrel domain protein
EYR27_RS16090	COG2086	electron transfer activity
EYR27_RS16100	COG3039	Transposase
EYR27_RS16160	COG0626	cystathionine gamma-synthase activity
EYR27_RS16190	COG0625	glutathione transferase activity
EYR27_RS16205	COG0513	Belongs to the DEAD box helicase family
EYR27_RS16215	COG0720	synthase
EYR27_RS16225	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EYR27_RS16230	COG1956	GAF domain-containing protein
EYR27_RS16240	COG0546	phosphoglycolate phosphatase activity
EYR27_RS16270	COG0339	signal peptide processing
EYR27_RS16315	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYR27_RS16320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYR27_RS16340	COG4191	Histidine kinase
EYR27_RS16365	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EYR27_RS16370	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EYR27_RS16375	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EYR27_RS16385	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EYR27_RS16395	COG0356	it plays a direct role in the translocation of protons across the membrane
EYR27_RS16415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYR27_RS16425	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYR27_RS16465	COG2011	ABC-type metal ion transport system permease component
EYR27_RS16475	COG0697	spore germination
EYR27_RS16515	COG1187	pseudouridine synthase activity
EYR27_RS16520	COG2813	Specifically methylates the guanine in position
EYR27_RS16530	COG3039	Transposase
EYR27_RS16595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYR27_RS16645	COG0745	RESPONSE REGULATOR receiver
EYR27_RS16660	COG1404	Belongs to the peptidase S8 family
EYR27_RS16675	COG0842	Transport permease protein
EYR27_RS16680	COG1131	(ABC) transporter
EYR27_RS16685	COG0025	NhaP-type Na H and K H
EYR27_RS16695	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EYR27_RS16705	COG1573	uracil-dna glycosylase
EYR27_RS16715	COG3384	dioxygenase
EYR27_RS16730	COG0667	Aldo Keto reductase
EYR27_RS16740	COG3590	peptidase
EYR27_RS16760	COG0531	amino acid
EYR27_RS16775	COG3275	phosphorelay sensor kinase activity
EYR27_RS16795	COG3685	Protein conserved in bacteria
EYR27_RS16855	COG1294	oxidase, subunit
EYR27_RS16885	COG1063	alcohol dehydrogenase
EYR27_RS16965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYR27_RS16975	COG1560	Kdo2-lipid A biosynthetic process
EYR27_RS17025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYR27_RS17025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EYR27_RS17030	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EYR27_RS17035	COG0242	peptide deformylase activity
EYR27_RS17040	COG1652	LysM domain
EYR27_RS17045	COG0758	DNA mediated transformation
EYR27_RS17070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYR27_RS17070	COG1754	DNA topoisomerase type I activity
EYR27_RS17075	COG0009	L-threonylcarbamoyladenylate synthase
EYR27_RS17090	COG1028	Short-chain dehydrogenase reductase Sdr
EYR27_RS17100	COG0616	signal peptide processing
EYR27_RS17105	COG0534	Mate efflux family protein
EYR27_RS17125	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYR27_RS17140	COG1252	NADH dehydrogenase
EYR27_RS17145	COG2860	membrane
EYR27_RS17150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYR27_RS17155	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EYR27_RS17160	COG3437	response regulator, receiver
EYR27_RS17165	COG2177	Part of the ABC transporter FtsEX involved in
EYR27_RS17170	COG2884	Cell division ATP-binding protein ftsE
EYR27_RS17180	COG3118	belongs to the thioredoxin family
EYR27_RS17185	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EYR27_RS17220	COG2826	transposase and inactivated derivatives, IS30 family
EYR27_RS17270	COG5383	Protein conserved in bacteria
EYR27_RS17295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYR27_RS17300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYR27_RS17305	COG1473	amidohydrolase
EYR27_RS17310	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EYR27_RS17310	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EYR27_RS17315	COG2826	transposase and inactivated derivatives, IS30 family
EYR27_RS17325	COG3023	N-Acetylmuramoyl-L-alanine amidase
EYR27_RS17335	COG4948	Mandelate Racemase Muconate Lactonizing
EYR27_RS17345	COG0531	amino acid
EYR27_RS17365	COG4682	membrane
EYR27_RS17370	COG2133	pyrroloquinoline quinone binding
EYR27_RS17435	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EYR27_RS17440	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EYR27_RS17450	COG1610	YqeY-like protein
EYR27_RS17465	COG1295	ribonuclease BN
EYR27_RS17470	COG0358	DNA primase activity
EYR27_RS17540	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EYR27_RS17555	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EYR27_RS17650	COG0676	glucose-6-phosphate 1-epimerase activity
EYR27_RS17665	COG0730	response to heat
EYR27_RS17695	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EYR27_RS17700	COG0302	gtp cyclohydrolase
EYR27_RS17730	COG0477	Major facilitator Superfamily
EYR27_RS17760	COG2826	transposase and inactivated derivatives, IS30 family
EYR27_RS17770	COG2853	Lipoprotein
EYR27_RS17785	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EYR27_RS17790	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EYR27_RS17795	COG1127	ABC transporter
EYR27_RS17830	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EYR27_RS17835	COG1074	ATP-dependent DNA helicase activity
EYR27_RS17845	COG3549	Plasmid maintenance system killer
EYR27_RS17945	COG0564	pseudouridine synthase activity
EYR27_RS17965	COG3039	Transposase
EYR27_RS17975	COG2826	transposase and inactivated derivatives, IS30 family
EYR27_RS18005	COG0714	Associated with various cellular activities
EYR27_RS18115	COG1272	protein, Hemolysin III
EYR27_RS18120	COG1205	dead DEAH box helicase
EYR27_RS18120	COG1111	helicase
EYR27_RS18190	COG0069	glutamate synthase activity
EYR27_RS18190	COG0070	glutamate synthase
EYR27_RS18190	COG0067	glutamate synthase
EYR27_RS18195	COG0493	'glutamate synthase
EYR27_RS18235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYR27_RS18280	COG1304	FMN binding
EYR27_RS18310	COG4772	TonB-dependent receptor
EYR27_RS18320	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EYR27_RS18360	COG0386	Belongs to the glutathione peroxidase family
EYR27_RS18370	COG1322	Protein conserved in bacteria
EYR27_RS18385	COG0531	amino acid
EYR27_RS18410	COG2199	diguanylate cyclase activity
EYR27_RS18410	COG2203	Gaf domain
EYR27_RS18420	COG1929	Belongs to the glycerate kinase type-1 family
EYR27_RS18425	COG2271	Major facilitator Superfamily
EYR27_RS18440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYR27_RS18450	COG0861	Integral membrane protein TerC family
EYR27_RS18460	COG0584	glycerophosphoryl diester phosphodiesterase
EYR27_RS18475	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EYR27_RS18510	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EYR27_RS18530	COG0187	DNA topoisomerase II activity
EYR27_RS18540	COG0501	Belongs to the peptidase M48B family
EYR27_RS18570	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EYR27_RS18580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYR27_RS18605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYR27_RS18615	COG0793	Belongs to the peptidase S41A family
EYR27_RS18620	COG4942	peptidase
EYR27_RS18630	COG2234	aminopeptidase activity
EYR27_RS18635	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYR27_RS18650	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYR27_RS18660	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYR27_RS18670	COG1064	alcohol dehydrogenase
EYR27_RS18760	COG0366	Alpha amylase catalytic
EYR27_RS18765	COG0366	Alpha amylase catalytic
EYR27_RS18775	COG2831	hemolysin activation secretion protein
EYR27_RS18860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EYR27_RS18875	COG2351	hydroxyisourate hydrolase activity
EYR27_RS18880	COG4807	Protein conserved in bacteria
EYR27_RS18885	COG3039	Transposase
EYR27_RS18895	COG1643	Atp-dependent helicase
EYR27_RS18910	COG1187	pseudouridine synthase activity
EYR27_RS18925	COG2130	NADP-dependent
EYR27_RS18930	COG0656	L-ascorbic acid biosynthetic process
EYR27_RS18970	COG1764	response to oxidative stress
EYR27_RS18975	COG1846	Transcriptional regulator
EYR27_RS18980	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EYR27_RS18990	COG0697	spore germination
EYR27_RS19055	COG1960	acyl-CoA dehydrogenase activity
EYR27_RS19060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYR27_RS19065	COG4770	biotin carboxylase activity
EYR27_RS19115	COG0339	signal peptide processing
EYR27_RS19145	COG0564	pseudouridine synthase activity
EYR27_RS19160	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EYR27_RS19175	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYR27_RS19190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYR27_RS19195	COG0318	PFAM AMP-dependent synthetase and ligase
EYR27_RS19200	COG0727	PFAM Uncharacterised protein family (UPF0153)
EYR27_RS19205	COG0596	Alpha beta hydrolase
EYR27_RS19210	COG3177	Filamentation induced by cAMP protein fic
EYR27_RS19215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYR27_RS19230	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EYR27_RS19255	COG4191	Histidine kinase
EYR27_RS19260	COG0028	Belongs to the TPP enzyme family
EYR27_RS19275	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EYR27_RS19280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYR27_RS19320	COG0183	Belongs to the thiolase family
EYR27_RS19350	COG2032	superoxide dismutase activity
EYR27_RS19355	COG2032	superoxide dismutase activity
EYR27_RS19360	COG2204	response regulator
EYR27_RS19365	COG3852	Histidine kinase
EYR27_RS19370	COG0004	ammonium transporteR
EYR27_RS19375	COG0347	Belongs to the P(II) protein family
EYR27_RS19380	COG0174	glutamine synthetase
EYR27_RS19385	COG1968	undecaprenyl-diphosphatase activity
EYR27_RS19430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYR27_RS19440	COG2062	phosphohistidine phosphatase, SixA
EYR27_RS19445	COG0489	protein tyrosine kinase activity
EYR27_RS19475	COG1396	sequence-specific DNA binding
EYR27_RS19480	COG3550	peptidyl-serine autophosphorylation
EYR27_RS19485	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EYR27_RS19490	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYR27_RS19505	COG1125	glycine betaine transport
EYR27_RS19530	COG1752	Esterase of the alpha-beta hydrolase superfamily
EYR27_RS19540	COG1522	sequence-specific DNA binding
EYR27_RS19545	COG3186	Phenylalanine-4-hydroxylase
EYR27_RS19570	COG1028	Short-chain dehydrogenase reductase Sdr
EYR27_RS19615	COG0084	hydrolase, TatD family'
EYR27_RS19630	COG0583	DNA-binding transcription factor activity
EYR27_RS19635	COG2814	Major facilitator Superfamily
EYR27_RS19650	COG1902	pentaerythritol trinitrate reductase activity
EYR27_RS19655	COG2084	Dehydrogenase
EYR27_RS19705	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYR27_RS19710	COG0583	DNA-binding transcription factor activity
EYR27_RS19740	COG0702	epimerase
EYR27_RS19745	COG1733	regulation of RNA biosynthetic process
EYR27_RS19785	COG0129	dihydroxy-acid dehydratase activity
EYR27_RS19795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EYR27_RS19875	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EYR27_RS19880	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EYR27_RS19890	COG3485	protocatechuate 3,4-dioxygenase
EYR27_RS19895	COG3485	protocatechuate 3,4-dioxygenase
EYR27_RS19910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYR27_RS19915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYR27_RS19925	COG1414	Transcriptional regulator
EYR27_RS19935	COG0657	acetylesterase activity
EYR27_RS19955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYR27_RS20000	COG0156	8-amino-7-oxononanoate synthase activity
EYR27_RS20005	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EYR27_RS20010	COG1040	competence protein
EYR27_RS20015	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EYR27_RS20110	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYR27_RS20185	COG3264	Mechanosensitive ion channel
EYR27_RS20185	COG1511	domain protein
EYR27_RS20200	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EYR27_RS20210	COG2354	Protein conserved in bacteria
EYR27_RS20215	COG1649	PFAM Uncharacterised BCR, COG1649
EYR27_RS20235	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EYR27_RS20260	COG0702	epimerase
EYR27_RS20305	COG3039	Transposase
EYR27_RS20355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYR27_RS20370	COG2951	lytic endotransglycosylase activity
EYR27_RS20390	COG3039	Transposase
EYR27_RS20410	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EYR27_RS20420	COG0842	Transport permease protein
EYR27_RS20425	COG1131	(ABC) transporter
EYR27_RS20430	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYR27_RS20460	COG1476	TRANSCRIPTIONal
EYR27_RS20470	COG4555	ABC transporter
EYR27_RS20510	COG0625	glutathione transferase activity
EYR27_RS20605	COG1199	ATP-dependent helicase activity
EYR27_RS20620	COG1566	PFAM secretion protein HlyD family protein
EYR27_RS20655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYR27_RS20685	COG3228	Belongs to the MtfA family
EYR27_RS20695	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EYR27_RS20695	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EYR27_RS20700	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EYR27_RS20720	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EYR27_RS20755	COG3237	CsbD-like
EYR27_RS20760	COG0180	Tryptophanyl-tRNA synthetase
EYR27_RS20765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYR27_RS20785	COG0697	spore germination
EYR27_RS20810	COG0753	catalase activity
EYR27_RS20825	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EYR27_RS20835	COG0628	permease
EYR27_RS20860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYR27_RS20875	COG0642	Histidine kinase
EYR27_RS20880	COG1090	epimerase
EYR27_RS20920	COG2826	transposase and inactivated derivatives, IS30 family
EYR27_RS20945	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EYR27_RS20965	COG0606	chelatase, subunit chli
EYR27_RS21015	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EYR27_RS21020	COG1166	arginine decarboxylase activity
EYR27_RS21035	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EYR27_RS21035	COG2755	lipolytic protein G-D-S-L family
EYR27_RS21040	COG4221	oxidoreductase activity
EYR27_RS21065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EYR27_RS21090	COG0463	Glycosyl transferase, family 2
EYR27_RS21105	COG1475	DNA binding
EYR27_RS21110	COG1192	Involved in chromosome partitioning
EYR27_RS21130	COG0582	viral genome integration into host DNA
EYR27_RS21225	COG1802	Transcriptional regulator
EYR27_RS21225	COG4626	Terminase
EYR27_RS21230	COG4695	Portal protein
EYR27_RS21235	COG0740	serine-type endopeptidase activity
EYR27_RS21375	COG3039	Transposase
EYR27_RS21395	COG0708	Exodeoxyribonuclease III
EYR27_RS21400	COG2211	Major facilitator Superfamily
EYR27_RS21420	COG0739	heme binding
EYR27_RS21460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EYR27_RS21485	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EYR27_RS21495	COG1435	thymidine kinase activity
EYR27_RS21500	COG0210	DNA helicase
EYR27_RS21520	COG2826	transposase and inactivated derivatives, IS30 family
EYR27_RS21530	COG0210	DNA helicase
EYR27_RS21570	COG4221	oxidoreductase activity
EYR27_RS21655	COG0697	spore germination
EYR27_RS21660	COG4305	rare lipoprotein A
EYR27_RS21665	COG5297	Belongs to the glycosyl hydrolase family 6
EYR27_RS21675	COG1113	amino acid transport
EYR27_RS21685	COG0598	Magnesium transport protein CorA
EYR27_RS21765	COG5297	Belongs to the glycosyl hydrolase family 6
EYR27_RS21765	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYR27_RS21770	COG0659	secondary active sulfate transmembrane transporter activity
EYR27_RS21810	COG3275	phosphorelay sensor kinase activity
EYR27_RS21820	COG0181	hydroxymethylbilane synthase activity
EYR27_RS21850	COG1505	serine-type exopeptidase activity
EYR27_RS21865	COG0436	Aminotransferase
EYR27_RS21875	COG2832	Protein of unknown function (DUF454)
EYR27_RS21900	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EYR27_RS21910	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EYR27_RS21950	COG2199	diguanylate cyclase activity
EYR27_RS21955	COG0308	aminopeptidase N
EYR27_RS21970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYR27_RS21975	COG1077	Cell shape determining protein MreB Mrl
EYR27_RS21980	COG1792	Involved in formation and maintenance of cell shape
EYR27_RS21995	COG0772	Belongs to the SEDS family
EYR27_RS22025	COG2951	lytic endotransglycosylase activity
EYR27_RS22030	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EYR27_RS22035	COG1686	Belongs to the peptidase S11 family
EYR27_RS22050	COG2921	Belongs to the UPF0250 family
EYR27_RS22075	COG1051	belongs to the nudix hydrolase family
EYR27_RS22075	COG1056	cytidyltransferase-related domain
EYR27_RS22110	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EYR27_RS22115	COG0673	inositol 2-dehydrogenase activity
EYR27_RS22120	COG2823	Periplasmic or secreted lipoprotein
EYR27_RS22125	COG4251	negative regulation of phosphorylation
EYR27_RS22130	COG0784	Response regulator, receiver
EYR27_RS22135	COG4191	Histidine kinase
EYR27_RS22140	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EYR27_RS22175	COG3250	beta-galactosidase activity
EYR27_RS22190	COG2188	Transcriptional regulator
EYR27_RS22200	COG1609	Transcriptional regulator
EYR27_RS22205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYR27_RS22210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EYR27_RS22225	COG1215	transferase activity, transferring glycosyl groups
EYR27_RS22230	COG1649	PFAM Uncharacterised BCR, COG1649
EYR27_RS22230	COG0726	polysaccharide deacetylase
EYR27_RS22270	COG2826	transposase and inactivated derivatives, IS30 family
EYR27_RS22325	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EYR27_RS22355	COG2205	protein histidine kinase activity
EYR27_RS22410	COG0488	(ABC) transporter
EYR27_RS22430	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EYR27_RS22440	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EYR27_RS22450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYR27_RS22450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYR27_RS22470	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EYR27_RS22475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYR27_RS22480	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EYR27_RS22505	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EYR27_RS22510	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EYR27_RS22520	COG2205	protein histidine kinase activity
EYR27_RS22525	COG0745	RESPONSE REGULATOR receiver
EYR27_RS22530	COG0277	FAD linked oxidase domain protein
EYR27_RS22540	COG0792	nuclease activity
EYR27_RS22580	COG0275	rRNA processing
EYR27_RS22585	COG3116	cell division
EYR27_RS22600	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EYR27_RS22605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYR27_RS22620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYR27_RS22625	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYR27_RS22630	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EYR27_RS22645	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EYR27_RS22655	COG4942	peptidase
EYR27_RS22655	COG1388	LysM domain
EYR27_RS22670	COG0494	nUDIX hydrolase
EYR27_RS22685	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EYR27_RS22750	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EYR27_RS22755	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EYR27_RS22800	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EYR27_RS22810	COG4106	trans-aconitate 2-methyltransferase activity
EYR27_RS22815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYR27_RS22825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYR27_RS22830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EYR27_RS22840	COG0667	Aldo Keto reductase
EYR27_RS22880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYR27_RS22900	COG4181	ATPase activity
EYR27_RS22915	COG0642	Histidine kinase
EYR27_RS22930	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EYR27_RS22950	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EYR27_RS22970	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EYR27_RS22975	COG2967	ApaG domain
EYR27_RS22980	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EYR27_RS22990	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EYR27_RS23005	COG0123	including yeast histone deacetylase and acetoin utilization protein
EYR27_RS23010	COG2096	Adenosyltransferase
EYR27_RS23025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYR27_RS23030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYR27_RS23050	COG1802	Transcriptional regulator
EYR27_RS23055	COG3384	dioxygenase
EYR27_RS23060	COG3384	dioxygenase
EYR27_RS23065	COG0583	DNA-binding transcription factor activity
EYR27_RS23070	COG0318	PFAM AMP-dependent synthetase and ligase
EYR27_RS23080	COG1024	Enoyl-CoA hydratase
EYR27_RS23100	COG3386	PFAM SMP-30 Gluconolaconase
EYR27_RS23135	COG0697	spore germination
EYR27_RS23175	COG5002	protein histidine kinase activity
EYR27_RS23175	COG0784	Response regulator, receiver
EYR27_RS23175	COG2205	protein histidine kinase activity
EYR27_RS23180	COG2197	response regulator
EYR27_RS23190	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYR27_RS23200	COG3039	Transposase
EYR27_RS23205	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EYR27_RS23210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYR27_RS23215	COG0583	DNA-binding transcription factor activity