locus-tag	class	description
BXO1_RS00005	COG0628	permease
BXO1_RS00015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BXO1_RS00020	COG3178	'Phosphotransferase
BXO1_RS00035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BXO1_RS00040	COG1555	photosystem II stabilization
BXO1_RS00085	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BXO1_RS00100	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BXO1_RS00125	COG0228	four-way junction DNA binding
BXO1_RS00130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BXO1_RS00135	COG0336	Belongs to the RNA methyltransferase TrmD family
BXO1_RS00150	COG0534	Mate efflux family protein
BXO1_RS00205	COG0542	response to heat
BXO1_RS00245	COG4206	TonB-dependent receptor
BXO1_RS00305	COG0019	diaminopimelate decarboxylase activity
BXO1_RS00315	COG2814	Major facilitator Superfamily
BXO1_RS00320	COG4264	IucA IucC family
BXO1_RS00330	COG4772	TonB-dependent receptor
BXO1_RS00345	COG4651	solute:proton antiporter activity
BXO1_RS00345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BXO1_RS00380	COG0488	(ABC) transporter
BXO1_RS00405	COG0657	acetylesterase activity
BXO1_RS00405	COG2755	lipolytic protein G-D-S-L family
BXO1_RS00430	COG2207	Transcriptional regulator
BXO1_RS00435	COG0326	Molecular chaperone. Has ATPase activity
BXO1_RS00470	COG0174	glutamine synthetase
BXO1_RS00475	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BXO1_RS00485	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BXO1_RS00500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BXO1_RS00525	COG2146	nitrite reductase [NAD(P)H] activity
BXO1_RS00540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BXO1_RS00545	COG0719	Fe-S assembly protein
BXO1_RS00550	COG0396	ATPase activity
BXO1_RS00555	COG0719	Fe-S assembly protein
BXO1_RS00560	COG1959	2 iron, 2 sulfur cluster binding
BXO1_RS00580	COG0693	protein deglycase activity
BXO1_RS00625	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BXO1_RS00660	COG0519	Catalyzes the synthesis of GMP from XMP
BXO1_RS00670	COG1678	Uncharacterized ACR, COG1678
BXO1_RS00675	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BXO1_RS00690	COG1764	response to oxidative stress
BXO1_RS00700	COG0384	phenazine biosynthesis protein PhzF
BXO1_RS00710	COG0527	aspartate kinase activity
BXO1_RS00740	COG0142	geranyltranstransferase activity
BXO1_RS00745	COG0629	single-stranded DNA binding
BXO1_RS00750	COG4251	negative regulation of phosphorylation
BXO1_RS00750	COG5001	Diguanylate cyclase
BXO1_RS00750	COG2203	Gaf domain
BXO1_RS00750	COG3706	GGDEF domain
BXO1_RS00795	COG2879	small protein
BXO1_RS00800	COG1966	Carbon starvation protein
BXO1_RS00805	COG1741	Belongs to the pirin family
BXO1_RS00875	COG1741	Belongs to the pirin family
BXO1_RS00885	COG1515	deoxyribonuclease V activity
BXO1_RS00890	COG0588	phosphoglycerate mutase activity
BXO1_RS00905	COG3590	peptidase
BXO1_RS00920	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BXO1_RS00925	COG2202	Pas domain
BXO1_RS00925	COG2200	EAL domain
BXO1_RS00925	COG2199	diguanylate cyclase activity
BXO1_RS00930	COG0835	chemotaxis
BXO1_RS00935	COG0840	transmembrane signaling receptor activity
BXO1_RS00945	COG2198	Histidine kinase
BXO1_RS00945	COG0643	Histidine kinase
BXO1_RS00960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BXO1_RS00970	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BXO1_RS00990	COG2205	protein histidine kinase activity
BXO1_RS01045	COG3039	Transposase
BXO1_RS01050	COG3039	Transposase
BXO1_RS01065	COG3039	Transposase
BXO1_RS01085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BXO1_RS01090	COG0735	belongs to the Fur family
BXO1_RS01150	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BXO1_RS01155	COG0084	hydrolase, TatD family'
BXO1_RS01170	COG1960	acyl-CoA dehydrogenase activity
BXO1_RS01185	COG0367	asparagine synthase
BXO1_RS01195	COG0305	Participates in initiation and elongation during chromosome replication
BXO1_RS01200	COG0415	Belongs to the DNA photolyase family
BXO1_RS01220	COG1028	Short-chain dehydrogenase reductase Sdr
BXO1_RS01320	COG5001	Diguanylate cyclase
BXO1_RS01320	COG5002	protein histidine kinase activity
BXO1_RS01325	COG1187	pseudouridine synthase activity
BXO1_RS01350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BXO1_RS01360	COG0475	glutathione-regulated potassium exporter activity
BXO1_RS01365	COG5002	protein histidine kinase activity
BXO1_RS01365	COG5000	phosphorelay sensor kinase activity
BXO1_RS01370	COG0745	RESPONSE REGULATOR receiver
BXO1_RS01400	COG1132	(ABC) transporter
BXO1_RS01475	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BXO1_RS01485	COG4969	Belongs to the N-Me-Phe pilin family
BXO1_RS01490	COG2194	sulfuric ester hydrolase activity
BXO1_RS01530	COG0045	succinate-CoA ligase (ADP-forming) activity
BXO1_RS01535	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BXO1_RS01545	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BXO1_RS01545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BXO1_RS01550	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXO1_RS01555	COG0564	pseudouridine synthase activity
BXO1_RS01580	COG3387	PFAM Glycoside hydrolase 15-related
BXO1_RS01585	COG1877	trehalose-phosphatase activity
BXO1_RS01625	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BXO1_RS01640	COG1595	DNA-templated transcription, initiation
BXO1_RS01650	COG1946	Acyl-CoA thioesterase
BXO1_RS01665	COG0824	Thioesterase
BXO1_RS01670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BXO1_RS01680	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BXO1_RS01685	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BXO1_RS01690	COG0268	Binds directly to 16S ribosomal RNA
BXO1_RS01695	COG0728	peptidoglycan biosynthetic process
BXO1_RS01700	COG0196	riboflavin kinase activity
BXO1_RS01710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BXO1_RS01715	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BXO1_RS01730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BXO1_RS01735	COG1845	cytochrome c oxidase, subunit III
BXO1_RS01740	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BXO1_RS01785	COG3209	COG3209 Rhs family protein
BXO1_RS01940	COG0632	four-way junction helicase activity
BXO1_RS01950	COG2255	four-way junction helicase activity
BXO1_RS01955	COG0824	Thioesterase
BXO1_RS01965	COG0848	biopolymer transport protein
BXO1_RS01980	COG2885	chlorophyll binding
BXO1_RS01990	COG0602	queuosine metabolic process
BXO1_RS02000	COG1187	pseudouridine synthase activity
BXO1_RS02045	COG3293	Transposase
BXO1_RS02060	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BXO1_RS02245	COG3179	chitinase
BXO1_RS02290	COG4695	Portal protein
BXO1_RS02340	COG3039	Transposase
BXO1_RS02370	COG0514	ATP-dependent DNA helicase (RecQ)
BXO1_RS02375	COG0783	Belongs to the Dps family
BXO1_RS02380	COG1643	Atp-dependent helicase
BXO1_RS02410	COG0535	radical SAM domain protein
BXO1_RS02415	COG0535	radical SAM domain protein
BXO1_RS02420	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BXO1_RS02435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BXO1_RS02445	COG1215	transferase activity, transferring glycosyl groups
BXO1_RS02450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BXO1_RS02460	COG1199	ATP-dependent helicase activity
BXO1_RS02470	COG1397	ADP-ribosylglycohydrolase
BXO1_RS02480	COG0189	ligase activity
BXO1_RS02495	COG0835	chemotaxis
BXO1_RS02500	COG0840	transmembrane signaling receptor activity
BXO1_RS02505	COG2198	Histidine kinase
BXO1_RS02505	COG0643	Histidine kinase
BXO1_RS02505	COG0784	Response regulator, receiver
BXO1_RS02530	COG3039	Transposase
BXO1_RS02565	COG1446	asparaginase
BXO1_RS02570	COG3142	Participates in the control of copper homeostasis
BXO1_RS02620	COG3537	Alpha-1,2-mannosidase
BXO1_RS02660	COG1472	Belongs to the glycosyl hydrolase 3 family
BXO1_RS02680	COG1388	LysM domain
BXO1_RS02680	COG3858	chitin binding
BXO1_RS02695	COG0837	glucose binding
BXO1_RS02700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BXO1_RS02710	COG0494	nUDIX hydrolase
BXO1_RS02720	COG3956	TIGRFAM MazG family protein
BXO1_RS02735	COG0330	HflC and HflK could
BXO1_RS02750	COG0509	glycine decarboxylation via glycine cleavage system
BXO1_RS02785	COG1960	acyl-CoA dehydrogenase activity
BXO1_RS02795	COG1309	transcriptional regulator
BXO1_RS02800	COG4771	TonB-dependent receptor
BXO1_RS02810	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BXO1_RS02820	COG0463	Glycosyl transferase, family 2
BXO1_RS02840	COG1272	protein, Hemolysin III
BXO1_RS02850	COG0739	heme binding
BXO1_RS02855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXO1_RS02860	COG0626	cystathionine gamma-synthase activity
BXO1_RS02870	COG1760	l-serine dehydratase
BXO1_RS02885	COG2353	YceI-like domain
BXO1_RS02895	COG2353	YceI-like domain
BXO1_RS02965	COG1960	acyl-CoA dehydrogenase activity
BXO1_RS02970	COG1024	Enoyl-CoA hydratase
BXO1_RS02990	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXO1_RS02990	COG1024	Enoyl-CoA hydratase
BXO1_RS03005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BXO1_RS03035	COG1381	Involved in DNA repair and RecF pathway recombination
BXO1_RS03050	COG2954	triphosphatase activity
BXO1_RS03060	COG3039	Transposase
BXO1_RS03095	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BXO1_RS03105	COG3046	protein related to deoxyribodipyrimidine photolyase
BXO1_RS03115	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BXO1_RS03120	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BXO1_RS03125	COG1278	Cold shock
BXO1_RS03145	COG1201	RNA secondary structure unwinding
BXO1_RS03150	COG1793	dna ligase
BXO1_RS03160	COG1793	dna ligase
BXO1_RS03160	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BXO1_RS03190	COG0183	Belongs to the thiolase family
BXO1_RS03215	COG1451	nucleotide metabolic process
BXO1_RS03230	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BXO1_RS03235	COG3039	Transposase
BXO1_RS03285	COG1047	Peptidyl-prolyl cis-trans
BXO1_RS03300	COG2824	Alkylphosphonate utilization operon protein PhnA
BXO1_RS03315	COG1902	pentaerythritol trinitrate reductase activity
BXO1_RS03320	COG2814	Major facilitator Superfamily
BXO1_RS03375	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BXO1_RS03375	COG0392	lysyltransferase activity
BXO1_RS03385	COG0251	oxidation-reduction process
BXO1_RS03390	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BXO1_RS03405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BXO1_RS03430	COG1595	DNA-templated transcription, initiation
BXO1_RS03450	COG2878	Part of a membrane complex involved in electron transport
BXO1_RS03460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BXO1_RS03460	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BXO1_RS03480	COG0833	amino acid
BXO1_RS03485	COG2040	homocysteine
BXO1_RS03500	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BXO1_RS03535	COG0529	Catalyzes the synthesis of activated sulfate
BXO1_RS03535	COG2895	sulfate adenylyltransferase (ATP) activity
BXO1_RS03580	COG1981	membrane
BXO1_RS03605	COG1131	(ABC) transporter
BXO1_RS03610	COG4771	TonB-dependent receptor
BXO1_RS03620	COG0825	malonyl-CoA metabolic process
BXO1_RS03640	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BXO1_RS03645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BXO1_RS03665	COG0750	zinc metalloprotease
BXO1_RS03675	COG0575	Belongs to the CDS family
BXO1_RS03685	COG0233	cytoplasmic translational termination
BXO1_RS03700	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BXO1_RS03765	COG1393	Belongs to the ArsC family
BXO1_RS03780	COG0367	asparagine synthase
BXO1_RS03790	COG4774	siderophore transport
BXO1_RS03820	COG2207	Transcriptional regulator
BXO1_RS03835	COG1566	PFAM secretion protein HlyD family protein
BXO1_RS03840	COG2814	Major facilitator Superfamily
BXO1_RS03895	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BXO1_RS03905	COG1960	acyl-CoA dehydrogenase activity
BXO1_RS03920	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BXO1_RS03930	COG2914	Belongs to the UPF0125 (RnfH) family
BXO1_RS03940	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXO1_RS03950	COG0497	DNA recombination
BXO1_RS03960	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BXO1_RS03965	COG0443	Heat shock 70 kDa protein
BXO1_RS03970	COG0484	heat shock protein binding
BXO1_RS03980	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BXO1_RS03985	COG0287	Prephenate dehydrogenase
BXO1_RS03985	COG1605	Chorismate mutase
BXO1_RS04005	COG0583	DNA-binding transcription factor activity
BXO1_RS04020	COG1132	(ABC) transporter
BXO1_RS04055	COG2850	peptidyl-arginine hydroxylation
BXO1_RS04120	COG1131	(ABC) transporter
BXO1_RS04125	COG1725	Transcriptional regulator
BXO1_RS04135	COG0386	Belongs to the glutathione peroxidase family
BXO1_RS04150	COG2900	Belongs to the SlyX family
BXO1_RS04165	COG1609	Transcriptional regulator
BXO1_RS04175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXO1_RS04185	COG0646	methionine synthase
BXO1_RS04185	COG1410	methionine synthase
BXO1_RS04190	COG1410	methionine synthase
BXO1_RS04190	COG0646	methionine synthase
BXO1_RS04195	COG2226	methyltransferase
BXO1_RS04200	COG1960	acyl-CoA dehydrogenase activity
BXO1_RS04230	COG0557	exoribonuclease II activity
BXO1_RS04250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BXO1_RS04265	COG3039	Transposase
BXO1_RS04390	COG0583	DNA-binding transcription factor activity
BXO1_RS04450	COG2201	protein-glutamate methylesterase activity
BXO1_RS04485	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BXO1_RS04490	COG0235	Class ii aldolase
BXO1_RS04495	COG0531	amino acid
BXO1_RS04500	COG0531	amino acid
BXO1_RS04510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BXO1_RS04515	COG0277	FAD linked oxidase domain protein
BXO1_RS04580	COG0436	Aminotransferase
BXO1_RS04605	COG1187	pseudouridine synthase activity
BXO1_RS04610	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BXO1_RS04615	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BXO1_RS04620	COG2350	Protein conserved in bacteria
BXO1_RS04650	COG1175	transmembrane transport
BXO1_RS04655	COG0395	ABC-type sugar transport system, permease component
BXO1_RS04680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BXO1_RS04690	COG2957	Belongs to the agmatine deiminase family
BXO1_RS04705	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BXO1_RS04710	COG0539	negative regulation of cytoplasmic translation
BXO1_RS04715	COG0776	regulation of translation
BXO1_RS04725	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BXO1_RS04730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BXO1_RS04740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BXO1_RS04760	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BXO1_RS04775	COG3002	Belongs to the UPF0753 family
BXO1_RS04780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BXO1_RS04785	COG0583	DNA-binding transcription factor activity
BXO1_RS04815	COG0583	DNA-binding transcription factor activity
BXO1_RS04820	COG0583	DNA-binding transcription factor activity
BXO1_RS04850	COG1914	H( )-stimulated, divalent metal cation uptake system
BXO1_RS04870	COG0668	transmembrane transport
BXO1_RS04895	COG1028	Short-chain dehydrogenase reductase Sdr
BXO1_RS04900	COG1183	phosphatidylcholine synthase activity
BXO1_RS04910	COG3243	poly(R)-hydroxyalkanoic acid synthase
BXO1_RS04925	COG0723	plastoquinol--plastocyanin reductase activity
BXO1_RS04925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXO1_RS04935	COG2183	response to ionizing radiation
BXO1_RS04950	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BXO1_RS04965	COG0671	phosphoesterase, PA-phosphatase related
BXO1_RS04990	COG1794	racemase activity, acting on amino acids and derivatives
BXO1_RS05000	COG0697	spore germination
BXO1_RS05005	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BXO1_RS05010	COG0167	dihydroorotate dehydrogenase activity
BXO1_RS05030	COG1012	belongs to the aldehyde dehydrogenase family
BXO1_RS05085	COG0124	histidyl-tRNA synthetase
BXO1_RS05105	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BXO1_RS05120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BXO1_RS05120	COG0131	Imidazoleglycerol-phosphate dehydratase
BXO1_RS05130	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BXO1_RS05140	COG0140	phosphoribosyl-ATP diphosphatase activity
BXO1_RS05140	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BXO1_RS05360	COG0653	protein targeting
BXO1_RS05390	COG3293	Transposase
BXO1_RS05405	COG2201	protein-glutamate methylesterase activity
BXO1_RS05415	COG2801	Transposase and inactivated derivatives
BXO1_RS05455	COG3328	transposase activity
BXO1_RS05490	COG0322	excinuclease ABC activity
BXO1_RS05500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BXO1_RS05510	COG1663	tetraacyldisaccharide 4'-kinase activity
BXO1_RS05525	COG0811	peptide transport
BXO1_RS05550	COG4591	ABC-type transport system involved in lipoprotein release permease component
BXO1_RS05565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BXO1_RS05580	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BXO1_RS05595	COG0354	folic acid binding
BXO1_RS05610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BXO1_RS05620	COG0363	glucosamine-6-phosphate deaminase activity
BXO1_RS05625	COG0129	dihydroxy-acid dehydratase activity
BXO1_RS05630	COG0800	Aldolase
BXO1_RS05665	COG2205	protein histidine kinase activity
BXO1_RS05665	COG5002	protein histidine kinase activity
BXO1_RS05665	COG0784	Response regulator, receiver
BXO1_RS05765	COG0386	Belongs to the glutathione peroxidase family
BXO1_RS05795	COG1595	DNA-templated transcription, initiation
BXO1_RS05855	COG5001	Diguanylate cyclase
BXO1_RS05855	COG4251	negative regulation of phosphorylation
BXO1_RS05855	COG3706	GGDEF domain
BXO1_RS05855	COG2203	Gaf domain
BXO1_RS05875	COG1472	Belongs to the glycosyl hydrolase 3 family
BXO1_RS05910	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BXO1_RS05915	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BXO1_RS05925	COG0617	tRNA 3'-terminal CCA addition
BXO1_RS05935	COG1469	GTP cyclohydrolase I activity
BXO1_RS05940	COG0860	N-Acetylmuramoyl-L-alanine amidase
BXO1_RS05995	COG4566	intracellular signal transduction
BXO1_RS06025	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BXO1_RS06030	COG1605	Chorismate mutase
BXO1_RS06030	COG0077	Prephenate dehydratase
BXO1_RS06040	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BXO1_RS06085	COG1228	amidohydrolase
BXO1_RS06090	COG2986	histidine ammonia-lyase
BXO1_RS06100	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BXO1_RS06125	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BXO1_RS06145	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BXO1_RS06160	COG3115	cell septum assembly
BXO1_RS06170	COG0359	binds to the 23S rRNA
BXO1_RS06180	COG0360	Binds together with S18 to 16S ribosomal RNA
BXO1_RS06185	COG0316	Belongs to the HesB IscA family
BXO1_RS06220	COG0288	reversible hydration of carbon dioxide
BXO1_RS06250	COG2925	Exonuclease
BXO1_RS06260	COG0667	Aldo Keto reductase
BXO1_RS06285	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BXO1_RS06285	COG0116	Belongs to the methyltransferase superfamily
BXO1_RS06330	COG0494	nUDIX hydrolase
BXO1_RS06340	COG1024	Enoyl-CoA hydratase
BXO1_RS06350	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BXO1_RS06395	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BXO1_RS06400	COG0573	inorganic phosphate transmembrane transporter activity
BXO1_RS06415	COG0704	Plays a role in the regulation of phosphate uptake
BXO1_RS06425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BXO1_RS06465	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BXO1_RS06470	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BXO1_RS06475	COG1862	Preprotein translocase
BXO1_RS06480	COG0343	queuine tRNA-ribosyltransferase activity
BXO1_RS06590	COG0405	Gamma-glutamyltransferase
BXO1_RS06595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BXO1_RS06610	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BXO1_RS06615	COG0742	ribosomal rna small subunit methyltransferase
BXO1_RS06675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BXO1_RS06730	COG0303	'Molybdopterin
BXO1_RS06740	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXO1_RS06750	COG1426	Protein conserved in bacteria
BXO1_RS06760	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BXO1_RS06775	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXO1_RS06775	COG1024	Enoyl-CoA hydratase
BXO1_RS06780	COG0183	Belongs to the thiolase family
BXO1_RS06785	COG0038	chloride channel
BXO1_RS06805	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BXO1_RS06830	COG1674	ftsk spoiiie
BXO1_RS06835	COG0492	ferredoxin-NADP+ reductase activity
BXO1_RS06860	COG0542	response to heat
BXO1_RS06875	COG0482	sulfurtransferase activity
BXO1_RS06900	COG5001	Diguanylate cyclase
BXO1_RS06905	COG4585	Histidine kinase
BXO1_RS06915	COG5002	protein histidine kinase activity
BXO1_RS06935	COG0784	Response regulator, receiver
BXO1_RS06935	COG0835	chemotaxis
BXO1_RS06945	COG1558	bacterial-type flagellum-dependent cell motility
BXO1_RS06950	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BXO1_RS06960	COG4787	bacterial-type flagellum-dependent cell motility
BXO1_RS07000	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BXO1_RS07005	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BXO1_RS07035	COG2201	protein-glutamate methylesterase activity
BXO1_RS07055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BXO1_RS07065	COG1028	Short-chain dehydrogenase reductase Sdr
BXO1_RS07100	COG1677	Flagellar hook-basal body complex protein FliE
BXO1_RS07150	COG3190	flagellar
BXO1_RS07170	COG1684	flagellar biosynthetic protein fliR
BXO1_RS07225	COG2198	Histidine kinase
BXO1_RS07225	COG0784	Response regulator, receiver
BXO1_RS07225	COG0643	Histidine kinase
BXO1_RS07280	COG3209	COG3209 Rhs family protein
BXO1_RS07400	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BXO1_RS07405	COG4988	ABC transporter
BXO1_RS07455	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BXO1_RS07475	COG0165	Argininosuccinate lyase
BXO1_RS07490	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BXO1_RS07495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BXO1_RS07505	COG0137	argininosuccinate synthase activity
BXO1_RS07510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BXO1_RS07530	COG2166	iron-sulfur cluster assembly
BXO1_RS07555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BXO1_RS07580	COG4677	pectinesterase activity
BXO1_RS07605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BXO1_RS07610	COG0402	S-adenosylhomocysteine deaminase activity
BXO1_RS07625	COG1509	lysine 2,3-aminomutase activity
BXO1_RS07630	COG3300	MHYT domain
BXO1_RS07630	COG5001	Diguanylate cyclase
BXO1_RS07645	COG0483	inositol monophosphate 1-phosphatase activity
BXO1_RS07650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BXO1_RS07675	COG0488	(ABC) transporter
BXO1_RS07680	COG0513	Belongs to the DEAD box helicase family
BXO1_RS07685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BXO1_RS07690	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BXO1_RS07700	COG0625	glutathione transferase activity
BXO1_RS07710	COG1671	Belongs to the UPF0178 family
BXO1_RS07715	COG4681	YaeQ
BXO1_RS07720	COG2081	HI0933 family
BXO1_RS07730	COG0501	Belongs to the peptidase M48B family
BXO1_RS07740	COG1028	Short-chain dehydrogenase reductase Sdr
BXO1_RS07765	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BXO1_RS07770	COG0860	N-Acetylmuramoyl-L-alanine amidase
BXO1_RS07775	COG0802	atpase or kinase
BXO1_RS07780	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BXO1_RS07780	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BXO1_RS07785	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BXO1_RS07805	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BXO1_RS07890	COG3328	transposase activity
BXO1_RS07935	COG2969	positive regulation of protein catabolic process
BXO1_RS07940	COG0625	glutathione transferase activity
BXO1_RS07945	COG2857	Cytochrome c1
BXO1_RS07950	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BXO1_RS07955	COG0723	plastoquinol--plastocyanin reductase activity
BXO1_RS07965	COG0741	lytic transglycosylase activity
BXO1_RS07990	COG1702	phosphate starvation-inducible protein PhoH
BXO1_RS08010	COG4535	Mg2 and Co2 transporter CorC
BXO1_RS08025	COG1012	belongs to the aldehyde dehydrogenase family
BXO1_RS08035	COG1177	transmembrane transport
BXO1_RS08045	COG3842	ATPase activity
BXO1_RS08090	COG0174	glutamine synthetase
BXO1_RS08095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXO1_RS08105	COG0477	Major facilitator Superfamily
BXO1_RS08115	COG0243	molybdopterin cofactor binding
BXO1_RS08125	COG2223	nitrite transmembrane transporter activity
BXO1_RS08135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BXO1_RS08140	COG1121	(ABC) transporter
BXO1_RS08150	COG2733	membrane
BXO1_RS08155	COG2205	protein histidine kinase activity
BXO1_RS08155	COG0784	Response regulator, receiver
BXO1_RS08155	COG5002	protein histidine kinase activity
BXO1_RS08165	COG3039	Transposase
BXO1_RS08175	COG2902	Dehydrogenase
BXO1_RS08185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXO1_RS08190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BXO1_RS08215	COG1609	Transcriptional regulator
BXO1_RS08220	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BXO1_RS08220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BXO1_RS08225	COG1105	Belongs to the carbohydrate kinase PfkB family
BXO1_RS08230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BXO1_RS08230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BXO1_RS08260	COG3039	Transposase
BXO1_RS08500	COG4771	TonB-dependent receptor
BXO1_RS08510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BXO1_RS08530	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BXO1_RS08535	COG1360	Flagellar Motor Protein
BXO1_RS08545	COG0835	chemotaxis
BXO1_RS08555	COG0745	RESPONSE REGULATOR receiver
BXO1_RS08595	COG0840	transmembrane signaling receptor activity
BXO1_RS08605	COG0840	transmembrane signaling receptor activity
BXO1_RS08615	COG0840	transmembrane signaling receptor activity
BXO1_RS08620	COG0840	transmembrane signaling receptor activity
BXO1_RS08625	COG0840	transmembrane signaling receptor activity
BXO1_RS08630	COG0840	transmembrane signaling receptor activity
BXO1_RS08650	COG0835	chemotaxis
BXO1_RS08670	COG3039	Transposase
BXO1_RS08690	COG0840	transmembrane signaling receptor activity
BXO1_RS08725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXO1_RS08755	COG0318	PFAM AMP-dependent synthetase and ligase
BXO1_RS08760	COG1024	Enoyl-CoA hydratase
BXO1_RS08765	COG2205	protein histidine kinase activity
BXO1_RS08765	COG2198	Histidine kinase
BXO1_RS08765	COG0784	Response regulator, receiver
BXO1_RS08840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BXO1_RS08850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BXO1_RS08855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BXO1_RS08865	COG0505	Belongs to the CarA family
BXO1_RS08870	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BXO1_RS08880	COG2258	MOSC domain
BXO1_RS08885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXO1_RS08935	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BXO1_RS08955	COG0477	Major facilitator Superfamily
BXO1_RS08965	COG1070	Carbohydrate kinase
BXO1_RS08975	COG1501	Belongs to the glycosyl hydrolase 31 family
BXO1_RS08990	COG0800	Aldolase
BXO1_RS08995	COG4948	Mandelate Racemase Muconate Lactonizing
BXO1_RS09005	COG3734	2-keto-3-deoxy-galactonokinase
BXO1_RS09010	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BXO1_RS09020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BXO1_RS09040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BXO1_RS09045	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BXO1_RS09055	COG0351	phosphomethylpyrimidine kinase
BXO1_RS09085	COG0583	DNA-binding transcription factor activity
BXO1_RS09090	COG1741	Belongs to the pirin family
BXO1_RS09115	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BXO1_RS09120	COG0305	Participates in initiation and elongation during chromosome replication
BXO1_RS09145	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BXO1_RS09150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BXO1_RS09155	COG2137	regulation of response to DNA damage stimulus
BXO1_RS09160	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BXO1_RS09175	COG1546	Belongs to the CinA family
BXO1_RS09180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BXO1_RS09190	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BXO1_RS09195	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BXO1_RS09205	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BXO1_RS09210	COG1534	Rna-binding protein
BXO1_RS09225	COG1238	metal cluster binding
BXO1_RS09230	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BXO1_RS09235	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BXO1_RS09240	COG2840	Smr protein MutS2
BXO1_RS09255	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BXO1_RS09265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BXO1_RS09270	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BXO1_RS09275	COG0148	phosphopyruvate hydratase activity
BXO1_RS09285	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BXO1_RS09290	COG0504	CTP synthase activity
BXO1_RS09320	COG0306	phosphate transporter
BXO1_RS09335	COG1253	flavin adenine dinucleotide binding
BXO1_RS09350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXO1_RS09370	COG0477	Major facilitator Superfamily
BXO1_RS09380	COG1132	(ABC) transporter
BXO1_RS09385	COG1136	(ABC) transporter
BXO1_RS09400	COG0438	transferase activity, transferring glycosyl groups
BXO1_RS09410	COG2264	protein methyltransferase activity
BXO1_RS09440	COG2244	polysaccharide biosynthetic process
BXO1_RS09490	COG1595	DNA-templated transcription, initiation
BXO1_RS09505	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BXO1_RS09525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BXO1_RS09565	COG2201	protein-glutamate methylesterase activity
BXO1_RS09585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BXO1_RS09590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXO1_RS09655	COG1858	cytochrome C peroxidase
BXO1_RS09690	COG0631	protein serine/threonine phosphatase activity
BXO1_RS09830	COG3039	Transposase
BXO1_RS09880	COG0316	Belongs to the HesB IscA family
BXO1_RS09880	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BXO1_RS09885	COG2154	pterin-4-alpha-carbinolamine dehydratase
BXO1_RS09895	COG0428	transporter
BXO1_RS09900	COG0428	transporter
BXO1_RS09905	COG3064	Membrane
BXO1_RS09915	COG1530	ribonuclease E activity
BXO1_RS09925	COG3293	Transposase
BXO1_RS09935	COG1054	Belongs to the UPF0176 family
BXO1_RS09955	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BXO1_RS09970	COG3039	Transposase
BXO1_RS10000	COG3039	Transposase
BXO1_RS10035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BXO1_RS10035	COG1648	precorrin-2 dehydrogenase activity
BXO1_RS10060	COG0746	molybdenum cofactor guanylyltransferase activity
BXO1_RS10130	COG3328	transposase activity
BXO1_RS10160	COG4206	TonB-dependent receptor
BXO1_RS10210	COG0531	amino acid
BXO1_RS10225	COG0006	proline dipeptidase activity
BXO1_RS10235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BXO1_RS10250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXO1_RS10255	COG3938	Belongs to the proline racemase family
BXO1_RS10265	COG0552	protein localization to endoplasmic reticulum
BXO1_RS10290	COG0784	Response regulator, receiver
BXO1_RS10290	COG4191	Histidine kinase
BXO1_RS10375	COG3040	lipid binding
BXO1_RS10415	COG0438	transferase activity, transferring glycosyl groups
BXO1_RS10425	COG0438	transferase activity, transferring glycosyl groups
BXO1_RS10430	COG0438	transferase activity, transferring glycosyl groups
BXO1_RS10485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BXO1_RS10500	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BXO1_RS10535	COG0556	nucleotide-excision repair
BXO1_RS10540	COG4969	Belongs to the N-Me-Phe pilin family
BXO1_RS10580	COG1611	Belongs to the LOG family
BXO1_RS10595	COG2095	MarC family integral membrane protein
BXO1_RS10605	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BXO1_RS10640	COG1185	polyribonucleotide nucleotidyltransferase activity
BXO1_RS10645	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BXO1_RS10660	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BXO1_RS10665	COG0195	Participates in both transcription termination and antitermination
BXO1_RS10670	COG0779	Required for maturation of 30S ribosomal subunits
BXO1_RS10680	COG1007	ATP synthesis coupled electron transport
BXO1_RS10710	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BXO1_RS10715	COG1034	ATP synthesis coupled electron transport
BXO1_RS10720	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BXO1_RS10725	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BXO1_RS10730	COG0649	NAD binding
BXO1_RS10735	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXO1_RS10745	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXO1_RS10760	COG0149	triose-phosphate isomerase activity
BXO1_RS10815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BXO1_RS10820	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BXO1_RS10830	COG0159	tryptophan synthase activity
BXO1_RS10850	COG0135	phosphoribosylanthranilate isomerase activity
BXO1_RS10855	COG0101	tRNA pseudouridine synthase activity
BXO1_RS10875	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BXO1_RS10880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BXO1_RS10885	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BXO1_RS10890	COG2890	protein-(glutamine-N5) methyltransferase activity
BXO1_RS10945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BXO1_RS10955	COG0412	Dienelactone hydrolase
BXO1_RS10975	COG0717	Belongs to the dCTP deaminase family
BXO1_RS10980	COG0489	protein tyrosine kinase activity
BXO1_RS11025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXO1_RS11030	COG2311	Membrane
BXO1_RS11035	COG1047	Peptidyl-prolyl cis-trans
BXO1_RS11040	COG0791	NLP P60 protein
BXO1_RS11045	COG0791	NLP P60 protein
BXO1_RS11065	COG1301	dicarboxylic acid transport
BXO1_RS11070	COG1785	Belongs to the alkaline phosphatase family
BXO1_RS11075	COG0037	tRNA processing
BXO1_RS11080	COG1722	exodeoxyribonuclease VII activity
BXO1_RS11085	COG0142	geranyltranstransferase activity
BXO1_RS11110	COG0312	modulator of DNA gyrase
BXO1_RS11115	COG3028	Belongs to the UPF0307 family
BXO1_RS11120	COG0312	modulator of DNA gyrase
BXO1_RS11130	COG3164	Protein of unknown function
BXO1_RS11145	COG2968	Membrane
BXO1_RS11175	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BXO1_RS11200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BXO1_RS11230	COG3118	belongs to the thioredoxin family
BXO1_RS11365	COG2022	thiamine diphosphate biosynthetic process
BXO1_RS11380	COG3273	potassium ion transport
BXO1_RS11380	COG0471	metal ion transport
BXO1_RS11410	COG1970	mechanosensitive ion channel activity
BXO1_RS11430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BXO1_RS11460	COG0308	aminopeptidase N
BXO1_RS11465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BXO1_RS11490	COG2895	sulfate adenylyltransferase (ATP) activity
BXO1_RS11490	COG0529	Catalyzes the synthesis of activated sulfate
BXO1_RS11495	COG0175	sulfate reduction
BXO1_RS11500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BXO1_RS11505	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BXO1_RS11510	COG0175	sulfate reduction
BXO1_RS11530	COG2198	Histidine kinase
BXO1_RS11530	COG2205	protein histidine kinase activity
BXO1_RS11530	COG0784	Response regulator, receiver
BXO1_RS11575	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BXO1_RS11580	COG3588	fructose-bisphosphate aldolase
BXO1_RS11585	COG0469	pyruvate kinase activity
BXO1_RS11630	COG0753	catalase activity
BXO1_RS11660	COG1917	Cupin 2, conserved barrel domain protein
BXO1_RS11660	COG2207	Transcriptional regulator
BXO1_RS11680	COG1506	peptidase
BXO1_RS11680	COG0823	Involved in the tonB-independent uptake of proteins
BXO1_RS11705	COG1297	OPT oligopeptide transporter protein
BXO1_RS11725	COG0587	DNA-directed DNA polymerase activity
BXO1_RS11805	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BXO1_RS11820	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BXO1_RS11825	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BXO1_RS11830	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BXO1_RS11850	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BXO1_RS12060	COG3179	chitinase
BXO1_RS12080	COG3328	transposase activity
BXO1_RS12125	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BXO1_RS12135	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BXO1_RS12145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BXO1_RS12255	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BXO1_RS12280	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BXO1_RS12295	COG2197	response regulator
BXO1_RS12300	COG4585	Histidine kinase
BXO1_RS12320	COG2894	cell division
BXO1_RS12325	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BXO1_RS12335	COG0642	Histidine kinase
BXO1_RS12340	COG0745	RESPONSE REGULATOR receiver
BXO1_RS12345	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BXO1_RS12355	COG2194	sulfuric ester hydrolase activity
BXO1_RS12385	COG3551	Protein conserved in bacteria
BXO1_RS12450	COG0203	ribosomal protein L17
BXO1_RS12460	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BXO1_RS12465	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BXO1_RS12475	COG0201	protein transport
BXO1_RS12485	COG1841	ribosomal large subunit assembly
BXO1_RS12515	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BXO1_RS12525	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BXO1_RS12530	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BXO1_RS12535	COG0255	Belongs to the universal ribosomal protein uL29 family
BXO1_RS12540	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BXO1_RS12550	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BXO1_RS12565	COG0089	rRNA binding
BXO1_RS12570	COG0088	Forms part of the polypeptide exit tunnel
BXO1_RS12575	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BXO1_RS12580	COG0051	transcription antitermination factor activity, RNA binding
BXO1_RS12600	COG0049	tRNA binding
BXO1_RS12605	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BXO1_RS12610	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BXO1_RS12615	COG0085	RNA polymerase activity
BXO1_RS12620	COG0222	ribosome binding
BXO1_RS12625	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BXO1_RS12635	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BXO1_RS12645	COG0250	Participates in transcription elongation, termination and antitermination
BXO1_RS12650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BXO1_RS12680	COG0012	GTP binding
BXO1_RS12685	COG0193	aminoacyl-tRNA hydrolase activity
BXO1_RS12695	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BXO1_RS12710	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BXO1_RS12720	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BXO1_RS12725	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BXO1_RS12735	COG0521	Mo-molybdopterin cofactor biosynthetic process
BXO1_RS12755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BXO1_RS12760	COG1295	ribonuclease BN
BXO1_RS12790	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BXO1_RS12800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BXO1_RS12830	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BXO1_RS12855	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BXO1_RS12870	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BXO1_RS12870	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BXO1_RS12910	COG2890	protein-(glutamine-N5) methyltransferase activity
BXO1_RS12920	COG3634	alkyl hydroperoxide reductase activity
BXO1_RS12925	COG0583	DNA-binding transcription factor activity
BXO1_RS12935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BXO1_RS12970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BXO1_RS13005	COG0584	glycerophosphoryl diester phosphodiesterase
BXO1_RS13045	COG3039	Transposase
BXO1_RS13065	COG0625	glutathione transferase activity
BXO1_RS13070	COG0039	L-malate dehydrogenase activity
BXO1_RS13075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BXO1_RS13080	COG1217	gtp-binding protein TYPA
BXO1_RS13100	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BXO1_RS13255	COG3781	membrane
BXO1_RS13265	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BXO1_RS13300	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BXO1_RS13320	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BXO1_RS13345	COG3710	Transcriptional regulator
BXO1_RS13350	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BXO1_RS13360	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BXO1_RS13390	COG2226	methyltransferase
BXO1_RS13395	COG0066	3-isopropylmalate dehydratase activity
BXO1_RS13400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BXO1_RS13430	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BXO1_RS13435	COG1538	Outer membrane efflux protein
BXO1_RS13440	COG1519	Transferase
BXO1_RS13445	COG1560	Kdo2-lipid A biosynthetic process
BXO1_RS13510	COG0308	aminopeptidase N
BXO1_RS13515	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BXO1_RS13525	COG0330	HflC and HflK could
BXO1_RS13530	COG0330	HflC and HflK could
BXO1_RS13550	COG0678	peroxiredoxin activity
BXO1_RS13560	COG2826	transposase and inactivated derivatives, IS30 family
BXO1_RS13655	COG3829	transcription factor binding
BXO1_RS13675	COG3039	Transposase
BXO1_RS13700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BXO1_RS13705	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BXO1_RS13715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BXO1_RS13720	COG1028	Short-chain dehydrogenase reductase Sdr
BXO1_RS13745	COG1399	metal-binding, possibly nucleic acid-binding protein
BXO1_RS13810	COG1518	maintenance of DNA repeat elements
BXO1_RS13815	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BXO1_RS13870	COG2188	Transcriptional regulator
BXO1_RS13885	COG1450	Type ii and iii secretion system protein
BXO1_RS13900	COG3166	PFAM Fimbrial assembly family protein
BXO1_RS13905	COG3156	type II secretion system protein K
BXO1_RS13910	COG4795	General secretion pathway protein
BXO1_RS13915	COG2165	general secretion pathway protein
BXO1_RS13920	COG4970	Tfp pilus assembly protein FimT
BXO1_RS13925	COG2165	general secretion pathway protein
BXO1_RS13930	COG1459	type II secretion system
BXO1_RS13940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BXO1_RS13950	COG5295	Hep Hag repeat protein
BXO1_RS13960	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BXO1_RS13960	COG0047	phosphoribosylformylglycinamidine synthase activity
BXO1_RS13965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BXO1_RS13970	COG4974	Belongs to the 'phage' integrase family
BXO1_RS13985	COG0795	lipopolysaccharide-transporting ATPase activity
BXO1_RS13995	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BXO1_RS14010	COG0525	valine-tRNA ligase activity
BXO1_RS14040	COG3039	Transposase
BXO1_RS14120	COG1183	phosphatidylcholine synthase activity
BXO1_RS14130	COG0442	prolyl-tRNA aminoacylation
BXO1_RS14150	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BXO1_RS14155	COG1127	ABC transporter
BXO1_RS14160	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BXO1_RS14160	COG3218	ABC-type transport auxiliary lipoprotein component
BXO1_RS14200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BXO1_RS14205	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BXO1_RS14205	COG0662	Cupin 2, conserved barrel domain protein
BXO1_RS14230	COG2086	electron transfer activity
BXO1_RS14255	COG3328	transposase activity
BXO1_RS14305	COG0626	cystathionine gamma-synthase activity
BXO1_RS14335	COG0625	glutathione transferase activity
BXO1_RS14350	COG0513	Belongs to the DEAD box helicase family
BXO1_RS14360	COG0720	synthase
BXO1_RS14370	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BXO1_RS14375	COG1956	GAF domain-containing protein
BXO1_RS14415	COG0339	signal peptide processing
BXO1_RS14465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BXO1_RS14470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXO1_RS14520	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BXO1_RS14525	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BXO1_RS14530	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BXO1_RS14535	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BXO1_RS14545	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BXO1_RS14555	COG0356	it plays a direct role in the translocation of protons across the membrane
BXO1_RS14575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BXO1_RS14585	COG0508	dehydrogenase complex catalyzes the overall conversion of
BXO1_RS14615	COG2011	ABC-type metal ion transport system permease component
BXO1_RS14625	COG0697	spore germination
BXO1_RS14665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BXO1_RS14670	COG1187	pseudouridine synthase activity
BXO1_RS14675	COG2813	Specifically methylates the guanine in position
BXO1_RS14705	COG2205	protein histidine kinase activity
BXO1_RS14705	COG2202	Pas domain
BXO1_RS14730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXO1_RS14780	COG0745	RESPONSE REGULATOR receiver
BXO1_RS14795	COG1404	Belongs to the peptidase S8 family
BXO1_RS14810	COG0842	Transport permease protein
BXO1_RS14815	COG1131	(ABC) transporter
BXO1_RS14820	COG0025	NhaP-type Na H and K H
BXO1_RS14830	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BXO1_RS14840	COG1573	uracil-dna glycosylase
BXO1_RS14850	COG3384	dioxygenase
BXO1_RS14865	COG0667	Aldo Keto reductase
BXO1_RS14880	COG3590	peptidase
BXO1_RS14900	COG0531	amino acid
BXO1_RS14915	COG2972	Histidine kinase
BXO1_RS14980	COG1271	oxidase subunit
BXO1_RS15155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BXO1_RS15165	COG1560	Kdo2-lipid A biosynthetic process
BXO1_RS15230	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BXO1_RS15235	COG0242	peptide deformylase activity
BXO1_RS15240	COG1652	LysM domain
BXO1_RS15245	COG0758	DNA mediated transformation
BXO1_RS15250	COG2922	Belongs to the Smg family
BXO1_RS15265	COG1754	DNA topoisomerase type I activity
BXO1_RS15265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BXO1_RS15270	COG0009	L-threonylcarbamoyladenylate synthase
BXO1_RS15285	COG1028	Short-chain dehydrogenase reductase Sdr
BXO1_RS15295	COG0616	signal peptide processing
BXO1_RS15300	COG0534	Mate efflux family protein
BXO1_RS15325	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BXO1_RS15355	COG1324	tolerance protein
BXO1_RS15375	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BXO1_RS15380	COG0511	ligase activity, forming carbon-carbon bonds
BXO1_RS15390	COG0439	Biotin carboxylase
BXO1_RS15445	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BXO1_RS15465	COG2267	carboxylic ester hydrolase activity
BXO1_RS15475	COG2267	carboxylic ester hydrolase activity
BXO1_RS15485	COG0138	bifunctional purine biosynthesis protein purh
BXO1_RS15495	COG0151	Belongs to the GarS family
BXO1_RS15500	COG1136	(ABC) transporter
BXO1_RS15500	COG0577	efflux transmembrane transporter activity
BXO1_RS15510	COG1289	transmembrane transporter activity
BXO1_RS15525	COG2814	Major facilitator Superfamily
BXO1_RS15550	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BXO1_RS15585	COG0745	RESPONSE REGULATOR receiver
BXO1_RS15630	COG0739	heme binding
BXO1_RS15650	COG2211	Major facilitator Superfamily
BXO1_RS15655	COG0708	Exodeoxyribonuclease III
BXO1_RS15670	COG1192	Involved in chromosome partitioning
BXO1_RS15675	COG1475	DNA binding
BXO1_RS15715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BXO1_RS15740	COG4221	oxidoreductase activity
BXO1_RS15765	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BXO1_RS15770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXO1_RS15790	COG3485	protocatechuate 3,4-dioxygenase
BXO1_RS15825	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BXO1_RS15835	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BXO1_RS15850	COG1042	CoA-binding domain protein
BXO1_RS15850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BXO1_RS15850	COG0045	succinate-CoA ligase (ADP-forming) activity
BXO1_RS15865	COG2239	Acts as a magnesium transporter
BXO1_RS15885	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BXO1_RS15905	COG3100	YcgL domain-containing protein
BXO1_RS15910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BXO1_RS15920	COG0463	Glycosyl transferase, family 2
BXO1_RS15935	COG1028	Short-chain dehydrogenase reductase Sdr
BXO1_RS15950	COG0156	8-amino-7-oxononanoate synthase activity
BXO1_RS15955	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BXO1_RS15960	COG1040	competence protein
BXO1_RS15965	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BXO1_RS15980	COG0628	permease
BXO1_RS15990	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BXO1_RS16005	COG0753	catalase activity
BXO1_RS16055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BXO1_RS16060	COG0180	Tryptophanyl-tRNA synthetase
BXO1_RS16065	COG3237	CsbD-like
BXO1_RS16105	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BXO1_RS16120	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BXO1_RS16125	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BXO1_RS16125	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BXO1_RS16165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BXO1_RS16195	COG1566	PFAM secretion protein HlyD family protein
BXO1_RS16215	COG1199	ATP-dependent helicase activity
BXO1_RS16250	COG0583	DNA-binding transcription factor activity
BXO1_RS16300	COG0625	glutathione transferase activity
BXO1_RS16335	COG4555	ABC transporter
BXO1_RS16345	COG1476	TRANSCRIPTIONal
BXO1_RS16370	COG1131	(ABC) transporter
BXO1_RS16375	COG0842	Transport permease protein
BXO1_RS16385	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BXO1_RS16470	COG1181	Belongs to the D-alanine--D-alanine ligase family
BXO1_RS16485	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BXO1_RS16495	COG0564	pseudouridine synthase activity
BXO1_RS16525	COG0339	signal peptide processing
BXO1_RS16555	COG3254	rhamnose metabolic process
BXO1_RS16560	COG0738	Major facilitator superfamily
BXO1_RS16565	COG1414	Transcriptional regulator
BXO1_RS16575	COG2205	protein histidine kinase activity
BXO1_RS16585	COG3459	Glycosyltransferase 36 associated
BXO1_RS16590	COG2211	Major facilitator Superfamily
BXO1_RS16595	COG3265	gluconokinase activity
BXO1_RS16615	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXO1_RS16695	COG1127	ABC transporter
BXO1_RS16700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BXO1_RS16705	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BXO1_RS16720	COG2853	Lipoprotein
BXO1_RS16750	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BXO1_RS16820	COG0676	glucose-6-phosphate 1-epimerase activity
BXO1_RS16840	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BXO1_RS16850	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BXO1_RS16860	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BXO1_RS16870	COG1064	alcohol dehydrogenase
BXO1_RS16920	COG1522	sequence-specific DNA binding
BXO1_RS16925	COG3186	Phenylalanine-4-hydroxylase
BXO1_RS16940	COG2755	lipolytic protein G-D-S-L family
BXO1_RS16970	COG2937	Belongs to the GPAT DAPAT family
BXO1_RS17005	COG0284	orotidine-5'-phosphate decarboxylase activity
BXO1_RS17015	COG3132	Protein of unknown function, DUF480
BXO1_RS17030	COG0210	DNA helicase
BXO1_RS17050	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BXO1_RS17075	COG1028	Short-chain dehydrogenase reductase Sdr
BXO1_RS17100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BXO1_RS17165	COG1166	arginine decarboxylase activity
BXO1_RS17170	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BXO1_RS17215	COG0606	chelatase, subunit chli
BXO1_RS17275	COG0366	Alpha amylase catalytic
BXO1_RS17280	COG0366	Alpha amylase catalytic
BXO1_RS17310	COG1609	Transcriptional regulator
BXO1_RS17360	COG0493	'glutamate synthase
BXO1_RS17365	COG0069	glutamate synthase activity
BXO1_RS17365	COG0070	glutamate synthase
BXO1_RS17365	COG0067	glutamate synthase
BXO1_RS17425	COG1205	dead DEAH box helicase
BXO1_RS17425	COG1111	helicase
BXO1_RS17430	COG1272	protein, Hemolysin III
BXO1_RS17475	COG1136	(ABC) transporter
BXO1_RS17510	COG1136	(ABC) transporter
BXO1_RS17560	COG3039	Transposase
BXO1_RS17570	COG0513	Belongs to the DEAD box helicase family
BXO1_RS17655	COG1858	cytochrome C peroxidase
BXO1_RS17670	COG0702	epimerase
BXO1_RS17695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BXO1_RS17715	COG1649	PFAM Uncharacterised BCR, COG1649
BXO1_RS17720	COG2354	Protein conserved in bacteria
BXO1_RS17730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BXO1_RS17745	COG1511	domain protein
BXO1_RS17745	COG3264	Mechanosensitive ion channel
BXO1_RS17825	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BXO1_RS17930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BXO1_RS17940	COG0642	Histidine kinase
BXO1_RS17950	COG1090	epimerase
BXO1_RS17960	COG3039	Transposase
BXO1_RS17985	COG2826	transposase and inactivated derivatives, IS30 family
BXO1_RS18005	COG3039	Transposase
BXO1_RS18080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXO1_RS18090	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BXO1_RS18110	COG1304	FMN binding
BXO1_RS18115	COG3039	Transposase
BXO1_RS18130	COG4772	TonB-dependent receptor
BXO1_RS18140	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BXO1_RS18150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BXO1_RS18160	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BXO1_RS18190	COG0501	Belongs to the peptidase M48B family
BXO1_RS18200	COG0187	DNA topoisomerase II activity
BXO1_RS18220	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BXO1_RS18245	COG0726	polysaccharide deacetylase
BXO1_RS18250	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BXO1_RS18255	COG0671	phosphoesterase, PA-phosphatase related
BXO1_RS18265	COG0584	glycerophosphoryl diester phosphodiesterase
BXO1_RS18275	COG0861	Integral membrane protein TerC family
BXO1_RS18285	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BXO1_RS18300	COG2271	Major facilitator Superfamily
BXO1_RS18305	COG1929	Belongs to the glycerate kinase type-1 family
BXO1_RS18400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BXO1_RS18410	COG0477	Major facilitator Superfamily
BXO1_RS18435	COG0302	gtp cyclohydrolase
BXO1_RS18440	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BXO1_RS18490	COG2234	aminopeptidase activity
BXO1_RS18500	COG4942	peptidase
BXO1_RS18505	COG0793	Belongs to the peptidase S41A family
BXO1_RS18570	COG0386	Belongs to the glutathione peroxidase family
BXO1_RS18580	COG1322	Protein conserved in bacteria
BXO1_RS18590	COG0531	amino acid
BXO1_RS18605	COG0210	DNA helicase
BXO1_RS18625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BXO1_RS18630	COG0583	DNA-binding transcription factor activity
BXO1_RS18635	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BXO1_RS18650	COG2159	amidohydrolase
BXO1_RS18680	COG0357	Ribosomal RNA small subunit methyltransferase G
BXO1_RS18685	COG3540	Alkaline phosphatase
BXO1_RS18695	COG2091	lysine biosynthetic process via aminoadipic acid
BXO1_RS18710	COG0708	Exodeoxyribonuclease III
BXO1_RS18725	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BXO1_RS18730	COG3162	membrane
BXO1_RS18770	COG3507	Belongs to the glycosyl hydrolase 43 family
BXO1_RS18790	COG1028	Short-chain dehydrogenase reductase Sdr
BXO1_RS18795	COG0179	Fumarylacetoacetate (FAA) hydrolase
BXO1_RS18805	COG4948	Mandelate Racemase Muconate Lactonizing
BXO1_RS18810	COG4807	Protein conserved in bacteria
BXO1_RS18815	COG1643	Atp-dependent helicase
BXO1_RS18830	COG1187	pseudouridine synthase activity
BXO1_RS18840	COG0667	Aldo Keto reductase
BXO1_RS18845	COG2130	NADP-dependent
BXO1_RS18850	COG0656	L-ascorbic acid biosynthetic process
BXO1_RS18875	COG3039	Transposase
BXO1_RS18890	COG1752	Esterase of the alpha-beta hydrolase superfamily
BXO1_RS18900	COG1119	ATPase activity
BXO1_RS18915	COG1125	glycine betaine transport
BXO1_RS18915	COG0517	IMP dehydrogenase activity
BXO1_RS18930	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BXO1_RS18935	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BXO1_RS18940	COG3550	peptidyl-serine autophosphorylation
BXO1_RS18945	COG1396	sequence-specific DNA binding
BXO1_RS18965	COG0489	protein tyrosine kinase activity
BXO1_RS18970	COG2062	phosphohistidine phosphatase, SixA
BXO1_RS18980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BXO1_RS19025	COG1968	undecaprenyl-diphosphatase activity
BXO1_RS19030	COG0174	glutamine synthetase
BXO1_RS19035	COG0347	Belongs to the P(II) protein family
BXO1_RS19040	COG0004	ammonium transporteR
BXO1_RS19045	COG3852	Histidine kinase
BXO1_RS19050	COG2204	response regulator
BXO1_RS19055	COG2032	superoxide dismutase activity
BXO1_RS19060	COG2032	superoxide dismutase activity
BXO1_RS19105	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BXO1_RS19110	COG1074	ATP-dependent DNA helicase activity
BXO1_RS19120	COG3549	Plasmid maintenance system killer
BXO1_RS19210	COG1764	response to oxidative stress
BXO1_RS19215	COG1846	Transcriptional regulator
BXO1_RS19255	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BXO1_RS19305	COG2211	Major facilitator Superfamily
BXO1_RS19330	COG3693	PFAM glycoside hydrolase, family 10
BXO1_RS19355	COG0246	Mannitol dehydrogenase
BXO1_RS19360	COG1472	Belongs to the glycosyl hydrolase 3 family
BXO1_RS19370	COG4948	Mandelate Racemase Muconate Lactonizing
BXO1_RS19380	COG3661	Belongs to the glycosyl hydrolase 67 family
BXO1_RS19400	COG0037	tRNA processing
BXO1_RS19405	COG2974	May be involved in recombination
BXO1_RS19430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BXO1_RS19440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BXO1_RS19450	COG0805	protein transport
BXO1_RS19460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BXO1_RS19460	COG0519	Catalyzes the synthesis of GMP from XMP
BXO1_RS19485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BXO1_RS19490	COG0752	glycyl-tRNA synthetase alpha subunit
BXO1_RS19500	COG0457	Tetratricopeptide repeat
BXO1_RS19505	COG4771	TonB-dependent receptor
BXO1_RS19520	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BXO1_RS19530	COG0697	spore germination
BXO1_RS19540	COG0523	cobalamin synthesis protein
BXO1_RS19595	COG1960	acyl-CoA dehydrogenase activity
BXO1_RS19600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BXO1_RS19605	COG4770	biotin carboxylase activity
BXO1_RS19670	COG2072	flavoprotein involved in K transport
BXO1_RS19690	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BXO1_RS19735	COG0084	hydrolase, TatD family'
BXO1_RS19755	COG0583	DNA-binding transcription factor activity
BXO1_RS19760	COG2814	Major facilitator Superfamily
BXO1_RS19770	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BXO1_RS19775	COG1902	pentaerythritol trinitrate reductase activity
BXO1_RS19805	COG0745	RESPONSE REGULATOR receiver
BXO1_RS19825	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BXO1_RS19830	COG0583	DNA-binding transcription factor activity
BXO1_RS19860	COG0702	epimerase
BXO1_RS19865	COG1733	regulation of RNA biosynthetic process
BXO1_RS19925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BXO1_RS19940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BXO1_RS19975	COG2911	Protein conserved in bacteria
BXO1_RS19980	COG0729	surface antigen
BXO1_RS19995	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BXO1_RS20000	COG3118	belongs to the thioredoxin family
BXO1_RS20010	COG2884	Cell division ATP-binding protein ftsE
BXO1_RS20015	COG2177	Part of the ABC transporter FtsEX involved in
BXO1_RS20020	COG3437	response regulator, receiver
BXO1_RS20025	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BXO1_RS20030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BXO1_RS20040	COG1252	NADH dehydrogenase
BXO1_RS20070	COG0459	protein refolding
BXO1_RS20080	COG4771	TonB-dependent receptor
BXO1_RS20095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BXO1_RS20145	COG3386	PFAM SMP-30 Gluconolaconase
BXO1_RS20160	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BXO1_RS20190	COG2353	YceI-like domain
BXO1_RS20250	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BXO1_RS20300	COG0408	coproporphyrinogen oxidase activity
BXO1_RS20310	COG3039	Transposase
BXO1_RS20335	COG0129	dihydroxy-acid dehydratase activity
BXO1_RS20345	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BXO1_RS20405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BXO1_RS20410	COG0318	PFAM AMP-dependent synthetase and ligase
BXO1_RS20415	COG0727	PFAM Uncharacterised protein family (UPF0153)
BXO1_RS20420	COG0596	Alpha beta hydrolase
BXO1_RS20435	COG3177	Filamentation induced by cAMP protein fic
BXO1_RS20440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BXO1_RS20455	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BXO1_RS20480	COG4191	Histidine kinase
BXO1_RS20490	COG0028	Belongs to the TPP enzyme family
BXO1_RS20505	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BXO1_RS20510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BXO1_RS20555	COG5383	Protein conserved in bacteria
BXO1_RS20570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BXO1_RS20575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXO1_RS20580	COG1473	amidohydrolase
BXO1_RS20590	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BXO1_RS20590	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BXO1_RS20715	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BXO1_RS20720	COG0134	indole-3-glycerol-phosphate synthase activity
BXO1_RS20730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXO1_RS20735	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BXO1_RS20750	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BXO1_RS20755	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BXO1_RS20760	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BXO1_RS20810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BXO1_RS20825	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BXO1_RS20890	COG0358	DNA primase activity
BXO1_RS20895	COG1295	ribonuclease BN
BXO1_RS20910	COG1610	YqeY-like protein
BXO1_RS20920	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BXO1_RS20925	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BXO1_RS20970	COG2133	pyrroloquinoline quinone binding
BXO1_RS20975	COG4682	membrane
BXO1_RS21000	COG0531	amino acid
BXO1_RS21030	COG4948	Mandelate Racemase Muconate Lactonizing
BXO1_RS21040	COG3023	N-Acetylmuramoyl-L-alanine amidase
BXO1_RS21045	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BXO1_RS21120	COG0183	Belongs to the thiolase family
BXO1_RS21160	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BXO1_RS21170	COG3483	tryptophan 2,3-dioxygenase activity
BXO1_RS21175	COG3104	oligopeptide transport
BXO1_RS21195	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BXO1_RS21205	COG1320	monovalent cation:proton antiporter activity
BXO1_RS21210	COG2212	antiporter activity
BXO1_RS21220	COG0651	ATP synthesis coupled electron transport
BXO1_RS21225	COG1006	Multisubunit Na H antiporter MnhC subunit
BXO1_RS21230	COG2111	Na H antiporter
BXO1_RS21230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BXO1_RS21275	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BXO1_RS21285	COG0456	acetyltransferase
BXO1_RS21315	COG4221	oxidoreductase activity
BXO1_RS21375	COG0697	spore germination
BXO1_RS21380	COG4305	rare lipoprotein A
BXO1_RS21385	COG5297	Belongs to the glycosyl hydrolase family 6
BXO1_RS21395	COG1113	amino acid transport
BXO1_RS21405	COG0598	Magnesium transport protein CorA
BXO1_RS21480	COG5297	Belongs to the glycosyl hydrolase family 6
BXO1_RS21480	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BXO1_RS21485	COG0659	secondary active sulfate transmembrane transporter activity
BXO1_RS21530	COG3275	phosphorelay sensor kinase activity
BXO1_RS21540	COG0181	hydroxymethylbilane synthase activity
BXO1_RS21565	COG1505	serine-type exopeptidase activity
BXO1_RS21590	COG3039	Transposase
BXO1_RS21600	COG0436	Aminotransferase
BXO1_RS21630	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BXO1_RS21660	COG0308	aminopeptidase N
BXO1_RS21665	COG2199	diguanylate cyclase activity
BXO1_RS21715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXO1_RS21720	COG1077	Cell shape determining protein MreB Mrl
BXO1_RS21725	COG1792	Involved in formation and maintenance of cell shape
BXO1_RS21740	COG0772	Belongs to the SEDS family
BXO1_RS21815	COG2951	lytic endotransglycosylase activity
BXO1_RS21820	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BXO1_RS21825	COG1686	Belongs to the peptidase S11 family
BXO1_RS21840	COG2921	Belongs to the UPF0250 family
BXO1_RS21865	COG1051	belongs to the nudix hydrolase family
BXO1_RS21865	COG1056	cytidyltransferase-related domain
BXO1_RS21900	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BXO1_RS21905	COG0673	inositol 2-dehydrogenase activity
BXO1_RS21910	COG2823	Periplasmic or secreted lipoprotein
BXO1_RS21915	COG4251	negative regulation of phosphorylation
BXO1_RS21920	COG0784	Response regulator, receiver
BXO1_RS21925	COG4191	Histidine kinase
BXO1_RS21930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BXO1_RS21980	COG3250	beta-galactosidase activity
BXO1_RS21995	COG2188	Transcriptional regulator
BXO1_RS22005	COG1609	Transcriptional regulator
BXO1_RS22010	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BXO1_RS22015	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BXO1_RS22025	COG1215	transferase activity, transferring glycosyl groups
BXO1_RS22030	COG0726	polysaccharide deacetylase
BXO1_RS22030	COG1649	PFAM Uncharacterised BCR, COG1649
BXO1_RS22125	COG3039	Transposase
BXO1_RS22155	COG3039	Transposase
BXO1_RS22190	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BXO1_RS22205	COG2205	protein histidine kinase activity
BXO1_RS22260	COG2205	protein histidine kinase activity
BXO1_RS22315	COG0488	(ABC) transporter
BXO1_RS22335	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BXO1_RS22355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BXO1_RS22355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BXO1_RS22375	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BXO1_RS22380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BXO1_RS22385	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BXO1_RS22410	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BXO1_RS22415	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BXO1_RS22425	COG2205	protein histidine kinase activity
BXO1_RS22430	COG0745	RESPONSE REGULATOR receiver
BXO1_RS22435	COG0277	FAD linked oxidase domain protein
BXO1_RS22440	COG1988	membrane-bound metal-dependent
BXO1_RS22445	COG0792	nuclease activity
BXO1_RS22480	COG0275	rRNA processing
BXO1_RS22485	COG3116	cell division
BXO1_RS22500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BXO1_RS22505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BXO1_RS22520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BXO1_RS22525	COG1181	Belongs to the D-alanine--D-alanine ligase family
BXO1_RS22530	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BXO1_RS22545	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BXO1_RS22555	COG4942	peptidase
BXO1_RS22555	COG1388	LysM domain
BXO1_RS22570	COG0494	nUDIX hydrolase
BXO1_RS22585	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BXO1_RS22600	COG3321	synthase
BXO1_RS22600	COG1028	Short-chain dehydrogenase reductase Sdr
BXO1_RS22600	COG0604	alcohol dehydrogenase
BXO1_RS22655	COG2226	methyltransferase
BXO1_RS22660	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BXO1_RS22715	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BXO1_RS22730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BXO1_RS22745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXO1_RS22750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BXO1_RS22760	COG3039	Transposase
BXO1_RS22770	COG0667	Aldo Keto reductase
BXO1_RS22785	COG3293	Transposase
BXO1_RS22825	COG2175	clavaminate synthase activity
BXO1_RS22835	COG4181	ATPase activity
BXO1_RS22850	COG0642	Histidine kinase
BXO1_RS22870	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BXO1_RS22890	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BXO1_RS22915	COG2967	ApaG domain
BXO1_RS22920	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BXO1_RS22930	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BXO1_RS22945	COG0123	including yeast histone deacetylase and acetoin utilization protein
BXO1_RS22950	COG2096	Adenosyltransferase
BXO1_RS22960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BXO1_RS22965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BXO1_RS23005	COG0583	DNA-binding transcription factor activity
BXO1_RS23010	COG0318	PFAM AMP-dependent synthetase and ligase
BXO1_RS23020	COG1024	Enoyl-CoA hydratase
BXO1_RS23040	COG3386	PFAM SMP-30 Gluconolaconase
BXO1_RS23170	COG1902	pentaerythritol trinitrate reductase activity
BXO1_RS23170	COG0446	pyridine nucleotide-disulphide oxidoreductase
BXO1_RS23175	COG0604	alcohol dehydrogenase
BXO1_RS23205	COG0156	8-amino-7-oxononanoate synthase activity
BXO1_RS23210	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BXO1_RS23215	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BXO1_RS23220	COG4208	sulfate ABC transporter
BXO1_RS23225	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BXO1_RS23260	COG0588	phosphoglycerate mutase activity
BXO1_RS23270	COG0285	dihydrofolate synthase activity
BXO1_RS23290	COG2833	Protein of unknown function (DUF455)
BXO1_RS23310	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BXO1_RS23315	COG0671	phosphoesterase, PA-phosphatase related
BXO1_RS23320	COG0438	transferase activity, transferring glycosyl groups
BXO1_RS23330	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BXO1_RS23345	COG4783	chaperone-mediated protein folding
BXO1_RS23370	COG0473	3-isopropylmalate dehydrogenase activity
BXO1_RS23425	COG0544	peptidyl-prolyl cis-trans isomerase activity
BXO1_RS23465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BXO1_RS23490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BXO1_RS23500	COG0631	protein serine/threonine phosphatase activity
BXO1_RS23555	COG0582	viral genome integration into host DNA
BXO1_RS23565	COG0859	PFAM glycosyl transferase family 9
BXO1_RS23570	COG3642	lipopolysaccharide core region biosynthetic process
BXO1_RS23575	COG1234	tRNA 3'-trailer cleavage
BXO1_RS23580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BXO1_RS23590	COG0315	cyclic pyranopterin monophosphate synthase activity
BXO1_RS23595	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BXO1_RS23600	COG0314	molybdopterin synthase activity
BXO1_RS23630	COG0537	adenosine 5'-monophosphoramidase activity
BXO1_RS23650	COG0714	Associated with various cellular activities
BXO1_RS23670	COG0242	peptide deformylase activity
BXO1_RS23720	COG3039	Transposase
BXO1_RS23730	COG3039	Transposase
BXO1_RS23765	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BXO1_RS23770	COG0726	polysaccharide deacetylase
BXO1_RS23795	COG1162	GTPase activity
BXO1_RS23830	COG1609	Transcriptional regulator
BXO1_RS23835	COG1028	Short-chain dehydrogenase reductase Sdr
BXO1_RS23840	COG2851	Citrate transporter
BXO1_RS23860	COG0642	Histidine kinase
BXO1_RS23870	COG2197	response regulator
BXO1_RS23890	COG0583	DNA-binding transcription factor activity
BXO1_RS23905	COG4191	Histidine kinase
BXO1_RS23925	COG0281	malic enzyme
BXO1_RS23925	COG0280	phosphate acetyltransferase
BXO1_RS23965	COG0352	thiamine-phosphate diphosphorylase activity
BXO1_RS23970	COG1773	rubredoxin
BXO1_RS23975	COG2912	Transglutaminase-like superfamily
BXO1_RS23985	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BXO1_RS23995	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BXO1_RS24020	COG0006	proline dipeptidase activity
BXO1_RS24050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BXO1_RS24065	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BXO1_RS24070	COG1561	YicC-like family, N-terminal region
BXO1_RS24095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BXO1_RS24105	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BXO1_RS24130	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BXO1_RS24175	COG0714	Associated with various cellular activities
BXO1_RS24195	COG2304	oxidoreductase activity
BXO1_RS24215	COG1301	dicarboxylic acid transport
BXO1_RS24220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BXO1_RS24230	COG0739	heme binding
BXO1_RS24235	COG1376	ErfK ybiS ycfS ynhG family protein
BXO1_RS24260	COG1022	Amp-dependent synthetase and ligase
BXO1_RS24270	COG1028	Short-chain dehydrogenase reductase Sdr
BXO1_RS24285	COG0642	Histidine kinase
BXO1_RS24305	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BXO1_RS24310	COG4149	molybdate abc transporter
BXO1_RS24315	COG0725	ABC transporter, periplasmic molybdate-binding protein
BXO1_RS24320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BXO1_RS24320	COG3453	Protein conserved in bacteria
BXO1_RS24350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BXO1_RS24370	COG2205	protein histidine kinase activity
BXO1_RS24375	COG0745	RESPONSE REGULATOR receiver
BXO1_RS24430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXO1_RS24435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BXO1_RS24485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BXO1_RS24500	COG2801	Transposase and inactivated derivatives
BXO1_RS24570	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BXO1_RS24585	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BXO1_RS24600	COG1842	Phage shock protein A
BXO1_RS24625	COG0754	glutathionylspermidine amidase activity
BXO1_RS24695	COG0531	amino acid
BXO1_RS24700	COG2197	response regulator
BXO1_RS24715	COG1113	amino acid transport
BXO1_RS24735	COG1271	oxidase subunit
BXO1_RS24740	COG1294	oxidase, subunit
BXO1_RS24750	COG2239	Acts as a magnesium transporter
BXO1_RS24760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BXO1_RS24765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BXO1_RS24775	COG1660	Displays ATPase and GTPase activities
BXO1_RS24780	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BXO1_RS24785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BXO1_RS24800	COG1137	ATPase activity
BXO1_RS24805	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BXO1_RS24815	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BXO1_RS24825	COG0271	Belongs to the BolA IbaG family
BXO1_RS24835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BXO1_RS24860	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BXO1_RS24875	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BXO1_RS25165	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BXO1_RS25220	COG0358	DNA primase activity
BXO1_RS25250	COG1192	Involved in chromosome partitioning
BXO1_RS25255	COG1475	DNA binding
BXO1_RS25285	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BXO1_RS25300	COG0741	lytic transglycosylase activity
BXO1_RS25315	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
BXO1_RS25320	COG2948	multi-organism process
BXO1_RS25335	COG3704	protein secretion by the type IV secretion system
BXO1_RS25350	COG3451	type IV secretory pathway VirB4