locus-tag	class	description
EBA03_RS00025	COG0187	DNA topoisomerase II activity
EBA03_RS00035	COG0501	Belongs to the peptidase M48B family
EBA03_RS00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EBA03_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA03_RS00095	COG3039	Transposase
EBA03_RS00145	COG0793	Belongs to the peptidase S41A family
EBA03_RS00150	COG4942	peptidase
EBA03_RS00160	COG2234	aminopeptidase activity
EBA03_RS00170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA03_RS00185	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA03_RS00195	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA03_RS00205	COG1064	alcohol dehydrogenase
EBA03_RS00235	COG0493	'glutamate synthase
EBA03_RS00240	COG0070	glutamate synthase
EBA03_RS00240	COG0069	glutamate synthase activity
EBA03_RS00240	COG0067	glutamate synthase
EBA03_RS00310	COG1111	helicase
EBA03_RS00310	COG1205	dead DEAH box helicase
EBA03_RS00315	COG1272	protein, Hemolysin III
EBA03_RS00345	COG2032	superoxide dismutase activity
EBA03_RS00350	COG2204	response regulator
EBA03_RS00355	COG3852	Histidine kinase
EBA03_RS00360	COG0004	ammonium transporteR
EBA03_RS00365	COG0347	Belongs to the P(II) protein family
EBA03_RS00370	COG0174	glutamine synthetase
EBA03_RS00375	COG1968	undecaprenyl-diphosphatase activity
EBA03_RS00425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA03_RS00435	COG2062	phosphohistidine phosphatase, SixA
EBA03_RS00440	COG0489	protein tyrosine kinase activity
EBA03_RS00460	COG1396	sequence-specific DNA binding
EBA03_RS00465	COG3550	peptidyl-serine autophosphorylation
EBA03_RS00470	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EBA03_RS00475	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA03_RS00490	COG1125	glycine betaine transport
EBA03_RS00505	COG1119	ATPase activity
EBA03_RS00520	COG1752	Esterase of the alpha-beta hydrolase superfamily
EBA03_RS00530	COG1522	sequence-specific DNA binding
EBA03_RS00535	COG3186	Phenylalanine-4-hydroxylase
EBA03_RS00565	COG1609	Transcriptional regulator
EBA03_RS00605	COG0366	Alpha amylase catalytic
EBA03_RS00610	COG0366	Alpha amylase catalytic
EBA03_RS00620	COG3039	Transposase
EBA03_RS00670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EBA03_RS00675	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EBA03_RS00690	COG0028	Belongs to the TPP enzyme family
EBA03_RS00695	COG4191	Histidine kinase
EBA03_RS00720	COG3039	Transposase
EBA03_RS00730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EBA03_RS00745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA03_RS00750	COG3177	Filamentation induced by cAMP protein fic
EBA03_RS00755	COG0596	Alpha beta hydrolase
EBA03_RS00765	COG0727	PFAM Uncharacterised protein family (UPF0153)
EBA03_RS00770	COG0318	PFAM AMP-dependent synthetase and ligase
EBA03_RS00775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EBA03_RS00790	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA03_RS00805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBA03_RS00820	COG0564	pseudouridine synthase activity
EBA03_RS00850	COG0339	signal peptide processing
EBA03_RS00895	COG4770	biotin carboxylase activity
EBA03_RS00900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EBA03_RS00905	COG1960	acyl-CoA dehydrogenase activity
EBA03_RS00950	COG0523	cobalamin synthesis protein
EBA03_RS00960	COG0697	spore germination
EBA03_RS00970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EBA03_RS00975	COG1846	Transcriptional regulator
EBA03_RS00980	COG1764	response to oxidative stress
EBA03_RS01030	COG0656	L-ascorbic acid biosynthetic process
EBA03_RS01045	COG2130	NADP-dependent
EBA03_RS01060	COG1187	pseudouridine synthase activity
EBA03_RS01075	COG1643	Atp-dependent helicase
EBA03_RS01085	COG4807	Protein conserved in bacteria
EBA03_RS01090	COG2072	flavoprotein involved in K transport
EBA03_RS01110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EBA03_RS01115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA03_RS01155	COG3039	Transposase
EBA03_RS01200	COG0084	hydrolase, TatD family'
EBA03_RS01220	COG0583	DNA-binding transcription factor activity
EBA03_RS01225	COG2814	Major facilitator Superfamily
EBA03_RS01235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EBA03_RS01240	COG1902	pentaerythritol trinitrate reductase activity
EBA03_RS01270	COG0745	RESPONSE REGULATOR receiver
EBA03_RS01290	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA03_RS01295	COG0583	DNA-binding transcription factor activity
EBA03_RS01325	COG0702	epimerase
EBA03_RS01330	COG1733	regulation of RNA biosynthetic process
EBA03_RS01365	COG3039	Transposase
EBA03_RS01400	COG0129	dihydroxy-acid dehydratase activity
EBA03_RS01410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EBA03_RS01480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EBA03_RS01495	COG3485	protocatechuate 3,4-dioxygenase
EBA03_RS01500	COG3485	protocatechuate 3,4-dioxygenase
EBA03_RS01515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA03_RS01520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EBA03_RS01535	COG1414	Transcriptional regulator
EBA03_RS01575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EBA03_RS01615	COG0156	8-amino-7-oxononanoate synthase activity
EBA03_RS01620	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EBA03_RS01625	COG1040	competence protein
EBA03_RS01630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EBA03_RS01735	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EBA03_RS01810	COG1511	domain protein
EBA03_RS01810	COG3264	Mechanosensitive ion channel
EBA03_RS01820	COG3039	Transposase
EBA03_RS01825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBA03_RS01835	COG2354	Protein conserved in bacteria
EBA03_RS01860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EBA03_RS01885	COG0702	epimerase
EBA03_RS01895	COG1028	Short-chain dehydrogenase reductase Sdr
EBA03_RS01940	COG0513	Belongs to the DEAD box helicase family
EBA03_RS01950	COG3039	Transposase
EBA03_RS01980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EBA03_RS01990	COG3483	tryptophan 2,3-dioxygenase activity
EBA03_RS01995	COG3104	oligopeptide transport
EBA03_RS02015	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EBA03_RS02025	COG1320	monovalent cation:proton antiporter activity
EBA03_RS02030	COG2212	antiporter activity
EBA03_RS02040	COG0651	ATP synthesis coupled electron transport
EBA03_RS02045	COG1006	Multisubunit Na H antiporter MnhC subunit
EBA03_RS02050	COG2111	Na H antiporter
EBA03_RS02050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA03_RS02085	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EBA03_RS02095	COG0456	acetyltransferase
EBA03_RS02135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EBA03_RS02140	COG0134	indole-3-glycerol-phosphate synthase activity
EBA03_RS02150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EBA03_RS02155	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EBA03_RS02165	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EBA03_RS02170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EBA03_RS02175	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EBA03_RS02245	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EBA03_RS02265	COG2814	Major facilitator Superfamily
EBA03_RS02275	COG2814	Major facilitator Superfamily
EBA03_RS02280	COG1289	transmembrane transporter activity
EBA03_RS02290	COG0151	Belongs to the GarS family
EBA03_RS02300	COG0419	ATPase involved in DNA repair
EBA03_RS02305	COG0138	bifunctional purine biosynthesis protein purh
EBA03_RS02310	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EBA03_RS02320	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EBA03_RS02380	COG0439	Biotin carboxylase
EBA03_RS02390	COG0511	ligase activity, forming carbon-carbon bonds
EBA03_RS02395	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EBA03_RS02410	COG1324	tolerance protein
EBA03_RS02430	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EBA03_RS02450	COG0534	Mate efflux family protein
EBA03_RS02455	COG0616	signal peptide processing
EBA03_RS02465	COG1028	Short-chain dehydrogenase reductase Sdr
EBA03_RS02480	COG0009	L-threonylcarbamoyladenylate synthase
EBA03_RS02485	COG1754	DNA topoisomerase type I activity
EBA03_RS02485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA03_RS02505	COG0758	DNA mediated transformation
EBA03_RS02510	COG1652	LysM domain
EBA03_RS02515	COG0242	peptide deformylase activity
EBA03_RS02520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EBA03_RS02525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBA03_RS02525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EBA03_RS02575	COG1560	Kdo2-lipid A biosynthetic process
EBA03_RS02585	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA03_RS02615	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EBA03_RS02620	COG3118	belongs to the thioredoxin family
EBA03_RS02630	COG2884	Cell division ATP-binding protein ftsE
EBA03_RS02635	COG2177	Part of the ABC transporter FtsEX involved in
EBA03_RS02640	COG3437	response regulator, receiver
EBA03_RS02645	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EBA03_RS02650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA03_RS02655	COG2860	membrane
EBA03_RS02660	COG1252	NADH dehydrogenase
EBA03_RS02685	COG0459	protein refolding
EBA03_RS02700	COG3039	Transposase
EBA03_RS02710	COG3039	Transposase
EBA03_RS02720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EBA03_RS02735	COG3386	PFAM SMP-30 Gluconolaconase
EBA03_RS02750	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA03_RS02795	COG2353	YceI-like domain
EBA03_RS02825	COG3039	Transposase
EBA03_RS02910	COG4221	oxidoreductase activity
EBA03_RS02970	COG0697	spore germination
EBA03_RS02975	COG4305	rare lipoprotein A
EBA03_RS02980	COG5297	Belongs to the glycosyl hydrolase family 6
EBA03_RS02995	COG1113	amino acid transport
EBA03_RS03005	COG0598	Magnesium transport protein CorA
EBA03_RS03085	COG5001	Diguanylate cyclase
EBA03_RS03085	COG3300	MHYT domain
EBA03_RS03110	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA03_RS03110	COG5297	Belongs to the glycosyl hydrolase family 6
EBA03_RS03115	COG0659	secondary active sulfate transmembrane transporter activity
EBA03_RS03150	COG3275	phosphorelay sensor kinase activity
EBA03_RS03160	COG0181	hydroxymethylbilane synthase activity
EBA03_RS03185	COG1505	serine-type exopeptidase activity
EBA03_RS03195	COG0436	Aminotransferase
EBA03_RS03205	COG2832	Protein of unknown function (DUF454)
EBA03_RS03225	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EBA03_RS03235	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EBA03_RS03270	COG3300	MHYT domain
EBA03_RS03270	COG5001	Diguanylate cyclase
EBA03_RS03275	COG0308	aminopeptidase N
EBA03_RS03290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA03_RS03295	COG1077	Cell shape determining protein MreB Mrl
EBA03_RS03300	COG1792	Involved in formation and maintenance of cell shape
EBA03_RS03315	COG0772	Belongs to the SEDS family
EBA03_RS03340	COG2951	lytic endotransglycosylase activity
EBA03_RS03345	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EBA03_RS03350	COG1686	Belongs to the peptidase S11 family
EBA03_RS03365	COG2921	Belongs to the UPF0250 family
EBA03_RS03390	COG1051	belongs to the nudix hydrolase family
EBA03_RS03390	COG1056	cytidyltransferase-related domain
EBA03_RS03425	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EBA03_RS03430	COG0673	inositol 2-dehydrogenase activity
EBA03_RS03435	COG2823	Periplasmic or secreted lipoprotein
EBA03_RS03440	COG4251	negative regulation of phosphorylation
EBA03_RS03445	COG0784	Response regulator, receiver
EBA03_RS03450	COG4191	Histidine kinase
EBA03_RS03455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EBA03_RS03480	COG3039	Transposase
EBA03_RS03500	COG3250	beta-galactosidase activity
EBA03_RS03515	COG2188	Transcriptional regulator
EBA03_RS03525	COG1609	Transcriptional regulator
EBA03_RS03530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA03_RS03535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EBA03_RS03550	COG1215	transferase activity, transferring glycosyl groups
EBA03_RS03555	COG1649	PFAM Uncharacterised BCR, COG1649
EBA03_RS03555	COG0726	polysaccharide deacetylase
EBA03_RS03580	COG3039	Transposase
EBA03_RS03625	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EBA03_RS03640	COG2205	protein histidine kinase activity
EBA03_RS03670	COG3791	Glutathione-dependent formaldehyde-activating
EBA03_RS03685	COG3039	Transposase
EBA03_RS03700	COG0488	(ABC) transporter
EBA03_RS03720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EBA03_RS03730	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EBA03_RS03740	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA03_RS03740	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA03_RS03760	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EBA03_RS03765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBA03_RS03770	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EBA03_RS03795	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EBA03_RS03800	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EBA03_RS03810	COG2205	protein histidine kinase activity
EBA03_RS03815	COG0745	RESPONSE REGULATOR receiver
EBA03_RS03845	COG0277	FAD linked oxidase domain protein
EBA03_RS03855	COG0792	nuclease activity
EBA03_RS03895	COG0275	rRNA processing
EBA03_RS03900	COG3116	cell division
EBA03_RS03915	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EBA03_RS03920	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA03_RS03935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBA03_RS03940	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA03_RS03945	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EBA03_RS03960	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EBA03_RS03970	COG0739	heme binding
EBA03_RS03970	COG0741	lytic transglycosylase activity
EBA03_RS03970	COG1196	nuclear chromosome segregation
EBA03_RS03985	COG0494	nUDIX hydrolase
EBA03_RS04000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EBA03_RS04015	COG3321	synthase
EBA03_RS04015	COG1028	Short-chain dehydrogenase reductase Sdr
EBA03_RS04015	COG0604	alcohol dehydrogenase
EBA03_RS04075	COG2226	methyltransferase
EBA03_RS04080	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EBA03_RS04120	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS04145	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EBA03_RS04160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA03_RS04170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA03_RS04175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EBA03_RS04185	COG0667	Aldo Keto reductase
EBA03_RS04210	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EBA03_RS04220	COG2175	clavaminate synthase activity
EBA03_RS04230	COG4181	ATPase activity
EBA03_RS04245	COG0642	Histidine kinase
EBA03_RS04260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EBA03_RS04280	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EBA03_RS04300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EBA03_RS04305	COG2967	ApaG domain
EBA03_RS04310	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EBA03_RS04325	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EBA03_RS04340	COG0123	including yeast histone deacetylase and acetoin utilization protein
EBA03_RS04345	COG2096	Adenosyltransferase
EBA03_RS04360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA03_RS04365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA03_RS04385	COG1802	Transcriptional regulator
EBA03_RS04395	COG3384	dioxygenase
EBA03_RS04400	COG0583	DNA-binding transcription factor activity
EBA03_RS04405	COG0318	PFAM AMP-dependent synthetase and ligase
EBA03_RS04415	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS04425	COG1024	Enoyl-CoA hydratase
EBA03_RS04445	COG3386	PFAM SMP-30 Gluconolaconase
EBA03_RS04495	COG2197	response regulator
EBA03_RS04505	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EBA03_RS04510	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EBA03_RS04515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA03_RS04525	COG0583	DNA-binding transcription factor activity
EBA03_RS04530	COG3634	alkyl hydroperoxide reductase activity
EBA03_RS04540	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA03_RS04580	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA03_RS04580	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA03_RS04595	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBA03_RS04650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EBA03_RS04660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EBA03_RS04690	COG1295	ribonuclease BN
EBA03_RS04695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA03_RS04700	COG1254	Belongs to the acylphosphatase family
EBA03_RS04715	COG0521	Mo-molybdopterin cofactor biosynthetic process
EBA03_RS04725	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EBA03_RS04730	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EBA03_RS04740	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EBA03_RS04755	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EBA03_RS04765	COG0193	aminoacyl-tRNA hydrolase activity
EBA03_RS04770	COG0012	GTP binding
EBA03_RS04805	COG0250	Participates in transcription elongation, termination and antitermination
EBA03_RS04815	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EBA03_RS04820	COG0081	regulation of translation
EBA03_RS04825	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EBA03_RS04835	COG0085	RNA polymerase activity
EBA03_RS04840	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EBA03_RS04845	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EBA03_RS04850	COG0049	tRNA binding
EBA03_RS04880	COG0088	Forms part of the polypeptide exit tunnel
EBA03_RS04885	COG0089	rRNA binding
EBA03_RS04890	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EBA03_RS04900	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EBA03_RS04910	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EBA03_RS04915	COG0255	Belongs to the universal ribosomal protein uL29 family
EBA03_RS04920	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EBA03_RS04925	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EBA03_RS04930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EBA03_RS04965	COG1841	ribosomal large subunit assembly
EBA03_RS04970	COG0200	Binds to the 23S rRNA
EBA03_RS04975	COG0201	protein transport
EBA03_RS04985	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EBA03_RS04990	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EBA03_RS05000	COG0203	ribosomal protein L17
EBA03_RS05020	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EBA03_RS05040	COG1217	gtp-binding protein TYPA
EBA03_RS05045	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EBA03_RS05055	COG0625	glutathione transferase activity
EBA03_RS05085	COG3039	Transposase
EBA03_RS05105	COG0446	pyridine nucleotide-disulphide oxidoreductase
EBA03_RS05105	COG1902	pentaerythritol trinitrate reductase activity
EBA03_RS05110	COG0604	alcohol dehydrogenase
EBA03_RS05140	COG0156	8-amino-7-oxononanoate synthase activity
EBA03_RS05145	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EBA03_RS05150	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EBA03_RS05155	COG4208	sulfate ABC transporter
EBA03_RS05160	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EBA03_RS05195	COG0406	alpha-ribazole phosphatase activity
EBA03_RS05205	COG0285	dihydrofolate synthase activity
EBA03_RS05225	COG2833	Protein of unknown function (DUF455)
EBA03_RS05250	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBA03_RS05255	COG0671	phosphoesterase, PA-phosphatase related
EBA03_RS05260	COG0438	transferase activity, transferring glycosyl groups
EBA03_RS05270	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EBA03_RS05275	COG5002	protein histidine kinase activity
EBA03_RS05285	COG4783	chaperone-mediated protein folding
EBA03_RS05300	COG0473	3-isopropylmalate dehydrogenase activity
EBA03_RS05340	COG3039	Transposase
EBA03_RS05365	COG0544	peptidyl-prolyl cis-trans isomerase activity
EBA03_RS05405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EBA03_RS05430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA03_RS05445	COG0631	protein serine/threonine phosphatase activity
EBA03_RS05480	COG0859	PFAM glycosyl transferase family 9
EBA03_RS05485	COG3642	lipopolysaccharide core region biosynthetic process
EBA03_RS05490	COG1234	tRNA 3'-trailer cleavage
EBA03_RS05495	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EBA03_RS05505	COG0315	cyclic pyranopterin monophosphate synthase activity
EBA03_RS05510	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EBA03_RS05515	COG0314	molybdopterin synthase activity
EBA03_RS05550	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EBA03_RS05560	COG0537	adenosine 5'-monophosphoramidase activity
EBA03_RS05580	COG0714	Associated with various cellular activities
EBA03_RS05600	COG1399	metal-binding, possibly nucleic acid-binding protein
EBA03_RS05625	COG1028	Short-chain dehydrogenase reductase Sdr
EBA03_RS05630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBA03_RS05640	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EBA03_RS05645	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EBA03_RS05675	COG3829	transcription factor binding
EBA03_RS05785	COG0330	HflC and HflK could
EBA03_RS05790	COG0330	HflC and HflK could
EBA03_RS05800	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EBA03_RS05805	COG0308	aminopeptidase N
EBA03_RS05820	COG0732	type I restriction modification DNA specificity domain
EBA03_RS05835	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EBA03_RS05920	COG0587	DNA-directed DNA polymerase activity
EBA03_RS05940	COG1297	OPT oligopeptide transporter protein
EBA03_RS05960	COG0823	Involved in the tonB-independent uptake of proteins
EBA03_RS05960	COG1506	peptidase
EBA03_RS05970	COG1917	Cupin 2, conserved barrel domain protein
EBA03_RS05970	COG2207	Transcriptional regulator
EBA03_RS06015	COG0753	catalase activity
EBA03_RS06055	COG3551	Protein conserved in bacteria
EBA03_RS06085	COG2194	sulfuric ester hydrolase activity
EBA03_RS06095	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EBA03_RS06100	COG0745	RESPONSE REGULATOR receiver
EBA03_RS06105	COG0642	Histidine kinase
EBA03_RS06115	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EBA03_RS06120	COG2894	cell division
EBA03_RS06135	COG4585	Histidine kinase
EBA03_RS06140	COG2197	response regulator
EBA03_RS06155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EBA03_RS06180	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EBA03_RS06255	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS06280	COG3039	Transposase
EBA03_RS06390	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EBA03_RS06405	COG1842	Phage shock protein A
EBA03_RS06430	COG0754	glutathionylspermidine amidase activity
EBA03_RS06510	COG0531	amino acid
EBA03_RS06515	COG2197	response regulator
EBA03_RS06530	COG1113	amino acid transport
EBA03_RS06560	COG3039	Transposase
EBA03_RS06570	COG1294	oxidase, subunit
EBA03_RS06580	COG2239	Acts as a magnesium transporter
EBA03_RS06590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA03_RS06595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA03_RS06610	COG3039	Transposase
EBA03_RS06625	COG1660	Displays ATPase and GTPase activities
EBA03_RS06635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA03_RS06650	COG1137	ATPase activity
EBA03_RS06655	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EBA03_RS06665	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EBA03_RS06675	COG0271	Belongs to the BolA IbaG family
EBA03_RS06680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EBA03_RS06705	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EBA03_RS06720	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EBA03_RS06730	COG0628	permease
EBA03_RS06740	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EBA03_RS06745	COG3178	'Phosphotransferase
EBA03_RS06755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA03_RS06760	COG1555	photosystem II stabilization
EBA03_RS06785	COG3039	Transposase
EBA03_RS06795	COG2146	nitrite reductase [NAD(P)H] activity
EBA03_RS06805	COG3039	Transposase
EBA03_RS06810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EBA03_RS06815	COG0719	Fe-S assembly protein
EBA03_RS06820	COG0396	ATPase activity
EBA03_RS06825	COG0719	Fe-S assembly protein
EBA03_RS06830	COG1959	2 iron, 2 sulfur cluster binding
EBA03_RS06885	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EBA03_RS06920	COG0519	Catalyzes the synthesis of GMP from XMP
EBA03_RS06935	COG1678	Uncharacterized ACR, COG1678
EBA03_RS06940	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EBA03_RS06955	COG1764	response to oxidative stress
EBA03_RS06965	COG0384	phenazine biosynthesis protein PhzF
EBA03_RS06975	COG0527	aspartate kinase activity
EBA03_RS07005	COG3039	Transposase
EBA03_RS07015	COG0142	geranyltranstransferase activity
EBA03_RS07020	COG0629	single-stranded DNA binding
EBA03_RS07025	COG4251	negative regulation of phosphorylation
EBA03_RS07025	COG2203	Gaf domain
EBA03_RS07025	COG3706	GGDEF domain
EBA03_RS07025	COG5001	Diguanylate cyclase
EBA03_RS07070	COG2879	small protein
EBA03_RS07075	COG1966	Carbon starvation protein
EBA03_RS07080	COG1741	Belongs to the pirin family
EBA03_RS07185	COG1515	deoxyribonuclease V activity
EBA03_RS07205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EBA03_RS07210	COG2202	Pas domain
EBA03_RS07210	COG2200	EAL domain
EBA03_RS07210	COG2199	diguanylate cyclase activity
EBA03_RS07215	COG0835	chemotaxis
EBA03_RS07220	COG0840	transmembrane signaling receptor activity
EBA03_RS07230	COG0643	Histidine kinase
EBA03_RS07230	COG2198	Histidine kinase
EBA03_RS07245	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EBA03_RS07255	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EBA03_RS07290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EBA03_RS07295	COG0735	belongs to the Fur family
EBA03_RS07325	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS07470	COG5001	Diguanylate cyclase
EBA03_RS07470	COG5002	protein histidine kinase activity
EBA03_RS07475	COG1187	pseudouridine synthase activity
EBA03_RS07495	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EBA03_RS07505	COG0475	glutathione-regulated potassium exporter activity
EBA03_RS07510	COG5000	phosphorelay sensor kinase activity
EBA03_RS07510	COG5002	protein histidine kinase activity
EBA03_RS07515	COG0745	RESPONSE REGULATOR receiver
EBA03_RS07520	COG1538	Outer membrane efflux protein
EBA03_RS07545	COG1132	(ABC) transporter
EBA03_RS07570	COG3039	Transposase
EBA03_RS07615	COG3118	belongs to the thioredoxin family
EBA03_RS07645	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EBA03_RS07665	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EBA03_RS07690	COG2968	Membrane
EBA03_RS07705	COG3164	Protein of unknown function
EBA03_RS07715	COG0312	modulator of DNA gyrase
EBA03_RS07720	COG3028	Belongs to the UPF0307 family
EBA03_RS07725	COG0312	modulator of DNA gyrase
EBA03_RS07740	COG4104	PAAR repeat-containing protein
EBA03_RS07750	COG0142	geranyltranstransferase activity
EBA03_RS07755	COG1722	exodeoxyribonuclease VII activity
EBA03_RS07760	COG0037	tRNA processing
EBA03_RS07765	COG1785	Belongs to the alkaline phosphatase family
EBA03_RS07770	COG1301	dicarboxylic acid transport
EBA03_RS07775	COG4106	trans-aconitate 2-methyltransferase activity
EBA03_RS07790	COG0791	NLP P60 protein
EBA03_RS07795	COG0791	NLP P60 protein
EBA03_RS07800	COG1047	Peptidyl-prolyl cis-trans
EBA03_RS07805	COG2311	Membrane
EBA03_RS07810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA03_RS07840	COG3039	Transposase
EBA03_RS07845	COG3039	Transposase
EBA03_RS07855	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS07885	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS07890	COG3039	Transposase
EBA03_RS07905	COG0489	protein tyrosine kinase activity
EBA03_RS07915	COG0717	Belongs to the dCTP deaminase family
EBA03_RS07930	COG3039	Transposase
EBA03_RS07950	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EBA03_RS07960	COG3039	Transposase
EBA03_RS07970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA03_RS07990	COG0433	COG0433 Predicted ATPase
EBA03_RS08020	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA03_RS08025	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EBA03_RS08030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBA03_RS08035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EBA03_RS08055	COG0101	tRNA pseudouridine synthase activity
EBA03_RS08060	COG0135	phosphoribosylanthranilate isomerase activity
EBA03_RS08070	COG0133	tryptophan synthase activity
EBA03_RS08085	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EBA03_RS08090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBA03_RS08150	COG0149	triose-phosphate isomerase activity
EBA03_RS08165	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA03_RS08175	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA03_RS08180	COG0649	NAD binding
EBA03_RS08185	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EBA03_RS08190	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EBA03_RS08195	COG1034	ATP synthesis coupled electron transport
EBA03_RS08200	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EBA03_RS08205	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA03_RS08230	COG1007	ATP synthesis coupled electron transport
EBA03_RS08240	COG0779	Required for maturation of 30S ribosomal subunits
EBA03_RS08245	COG0195	Participates in both transcription termination and antitermination
EBA03_RS08250	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EBA03_RS08265	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EBA03_RS08270	COG1185	polyribonucleotide nucleotidyltransferase activity
EBA03_RS08305	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA03_RS08315	COG2095	MarC family integral membrane protein
EBA03_RS08330	COG1611	Belongs to the LOG family
EBA03_RS08370	COG4969	Belongs to the N-Me-Phe pilin family
EBA03_RS08375	COG0556	nucleotide-excision repair
EBA03_RS08405	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EBA03_RS08415	COG2986	histidine ammonia-lyase
EBA03_RS08420	COG1228	amidohydrolase
EBA03_RS08465	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EBA03_RS08470	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EBA03_RS08475	COG1605	Chorismate mutase
EBA03_RS08475	COG0077	Prephenate dehydratase
EBA03_RS08480	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EBA03_RS08505	COG3039	Transposase
EBA03_RS08515	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EBA03_RS08530	COG0583	DNA-binding transcription factor activity
EBA03_RS08545	COG2336	PFAM SpoVT AbrB
EBA03_RS08585	COG0840	transmembrane signaling receptor activity
EBA03_RS08610	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EBA03_RS08615	COG0784	Response regulator, receiver
EBA03_RS08615	COG4191	Histidine kinase
EBA03_RS08630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA03_RS08650	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA03_RS08665	COG1595	DNA-templated transcription, initiation
EBA03_RS08715	COG2244	polysaccharide biosynthetic process
EBA03_RS08745	COG2264	protein methyltransferase activity
EBA03_RS08755	COG0438	transferase activity, transferring glycosyl groups
EBA03_RS08770	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EBA03_RS08775	COG1132	(ABC) transporter
EBA03_RS08785	COG2271	Major facilitator Superfamily
EBA03_RS08805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBA03_RS08820	COG1253	flavin adenine dinucleotide binding
EBA03_RS08835	COG0306	phosphate transporter
EBA03_RS08865	COG0504	CTP synthase activity
EBA03_RS08870	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EBA03_RS08875	COG0148	phosphopyruvate hydratase activity
EBA03_RS08880	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EBA03_RS08895	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EBA03_RS08905	COG2840	Smr protein MutS2
EBA03_RS08910	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EBA03_RS08915	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBA03_RS08920	COG1238	metal cluster binding
EBA03_RS08935	COG1534	Rna-binding protein
EBA03_RS08940	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EBA03_RS08950	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EBA03_RS08965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EBA03_RS08970	COG1546	Belongs to the CinA family
EBA03_RS08985	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EBA03_RS08995	COG2137	regulation of response to DNA damage stimulus
EBA03_RS09000	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EBA03_RS09005	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EBA03_RS09055	COG1741	Belongs to the pirin family
EBA03_RS09060	COG0583	DNA-binding transcription factor activity
EBA03_RS09085	COG0351	phosphomethylpyrimidine kinase
EBA03_RS09085	COG0352	thiamine-phosphate diphosphorylase activity
EBA03_RS09095	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EBA03_RS09100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EBA03_RS09115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA03_RS09125	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EBA03_RS09130	COG3734	2-keto-3-deoxy-galactonokinase
EBA03_RS09140	COG4948	Mandelate Racemase Muconate Lactonizing
EBA03_RS09145	COG0800	Aldolase
EBA03_RS09170	COG1070	Carbohydrate kinase
EBA03_RS09180	COG0477	Major facilitator Superfamily
EBA03_RS09200	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA03_RS09205	COG1469	GTP cyclohydrolase I activity
EBA03_RS09215	COG0617	tRNA 3'-terminal CCA addition
EBA03_RS09235	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EBA03_RS09265	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA03_RS09285	COG4251	negative regulation of phosphorylation
EBA03_RS09285	COG5001	Diguanylate cyclase
EBA03_RS09285	COG2203	Gaf domain
EBA03_RS09285	COG3706	GGDEF domain
EBA03_RS09295	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA03_RS09305	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EBA03_RS09320	COG0671	phosphoesterase, PA-phosphatase related
EBA03_RS09340	COG1794	racemase activity, acting on amino acids and derivatives
EBA03_RS09350	COG0697	spore germination
EBA03_RS09355	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EBA03_RS09380	COG1012	belongs to the aldehyde dehydrogenase family
EBA03_RS09445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EBA03_RS09460	COG0124	histidyl-tRNA synthetase
EBA03_RS09485	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EBA03_RS09500	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EBA03_RS09500	COG0131	Imidazoleglycerol-phosphate dehydratase
EBA03_RS09510	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EBA03_RS09520	COG0140	phosphoribosyl-ATP diphosphatase activity
EBA03_RS09520	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EBA03_RS09540	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EBA03_RS09545	COG0235	Class ii aldolase
EBA03_RS09550	COG0531	amino acid
EBA03_RS09555	COG0531	amino acid
EBA03_RS09565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EBA03_RS09570	COG0277	FAD linked oxidase domain protein
EBA03_RS09595	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EBA03_RS09645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBA03_RS09650	COG2258	MOSC domain
EBA03_RS09655	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EBA03_RS09660	COG0505	Belongs to the CarA family
EBA03_RS09670	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EBA03_RS09675	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA03_RS09685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EBA03_RS09700	COG3279	Response regulator of the LytR AlgR family
EBA03_RS09725	COG0784	Response regulator, receiver
EBA03_RS09725	COG2198	Histidine kinase
EBA03_RS09725	COG2205	protein histidine kinase activity
EBA03_RS09730	COG1024	Enoyl-CoA hydratase
EBA03_RS09735	COG0318	PFAM AMP-dependent synthetase and ligase
EBA03_RS09765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA03_RS09795	COG0840	transmembrane signaling receptor activity
EBA03_RS09805	COG0835	chemotaxis
EBA03_RS09820	COG0840	transmembrane signaling receptor activity
EBA03_RS09825	COG0840	transmembrane signaling receptor activity
EBA03_RS09830	COG0840	transmembrane signaling receptor activity
EBA03_RS09845	COG0840	transmembrane signaling receptor activity
EBA03_RS09855	COG0840	transmembrane signaling receptor activity
EBA03_RS09860	COG0840	transmembrane signaling receptor activity
EBA03_RS09890	COG0840	transmembrane signaling receptor activity
EBA03_RS09895	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS09915	COG0745	RESPONSE REGULATOR receiver
EBA03_RS09925	COG0835	chemotaxis
EBA03_RS09930	COG1192	Involved in chromosome partitioning
EBA03_RS09935	COG1360	Flagellar Motor Protein
EBA03_RS09940	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EBA03_RS09960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA03_RS10000	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS10005	COG3039	Transposase
EBA03_RS10070	COG0784	Response regulator, receiver
EBA03_RS10070	COG0643	Histidine kinase
EBA03_RS10070	COG2198	Histidine kinase
EBA03_RS10125	COG1684	flagellar biosynthetic protein fliR
EBA03_RS10140	COG3190	flagellar
EBA03_RS10190	COG1677	Flagellar hook-basal body complex protein FliE
EBA03_RS10225	COG1028	Short-chain dehydrogenase reductase Sdr
EBA03_RS10235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA03_RS10255	COG2201	protein-glutamate methylesterase activity
EBA03_RS10285	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EBA03_RS10290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EBA03_RS10305	COG3951	Flagellar rod assembly protein muramidase FlgJ
EBA03_RS10305	COG1705	Flagellar rod assembly protein muramidase FlgJ
EBA03_RS10310	COG1706	bacterial-type flagellum-dependent cell motility
EBA03_RS10315	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EBA03_RS10330	COG4787	bacterial-type flagellum-dependent cell motility
EBA03_RS10340	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EBA03_RS10345	COG1558	bacterial-type flagellum-dependent cell motility
EBA03_RS10355	COG0835	chemotaxis
EBA03_RS10355	COG0784	Response regulator, receiver
EBA03_RS10375	COG5002	protein histidine kinase activity
EBA03_RS10385	COG4585	Histidine kinase
EBA03_RS10420	COG0482	sulfurtransferase activity
EBA03_RS10435	COG0542	response to heat
EBA03_RS10460	COG0492	ferredoxin-NADP+ reductase activity
EBA03_RS10465	COG1674	ftsk spoiiie
EBA03_RS10490	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EBA03_RS10510	COG0038	chloride channel
EBA03_RS10515	COG0183	Belongs to the thiolase family
EBA03_RS10520	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA03_RS10520	COG1024	Enoyl-CoA hydratase
EBA03_RS10535	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EBA03_RS10555	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA03_RS10560	COG1160	GTP binding
EBA03_RS10565	COG0303	'Molybdopterin
EBA03_RS10575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EBA03_RS10585	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS10595	COG3039	Transposase
EBA03_RS10620	COG0746	molybdenum cofactor guanylyltransferase activity
EBA03_RS10645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EBA03_RS10645	COG1648	precorrin-2 dehydrogenase activity
EBA03_RS10680	COG3039	Transposase
EBA03_RS10705	COG3039	Transposase
EBA03_RS10715	COG5001	Diguanylate cyclase
EBA03_RS10745	COG4566	intracellular signal transduction
EBA03_RS10800	COG2201	protein-glutamate methylesterase activity
EBA03_RS10875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EBA03_RS10880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EBA03_RS10965	COG1024	Enoyl-CoA hydratase
EBA03_RS10970	COG1024	Enoyl-CoA hydratase
EBA03_RS10980	COG1024	Enoyl-CoA hydratase
EBA03_RS10995	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EBA03_RS11010	COG3039	Transposase
EBA03_RS11025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA03_RS11030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA03_RS11080	COG1858	cytochrome C peroxidase
EBA03_RS11110	COG0515	serine threonine protein kinase
EBA03_RS11115	COG0631	protein serine/threonine phosphatase activity
EBA03_RS11180	COG3039	Transposase
EBA03_RS11265	COG3039	Transposase
EBA03_RS11280	COG2154	pterin-4-alpha-carbinolamine dehydratase
EBA03_RS11295	COG3064	Membrane
EBA03_RS11305	COG1530	ribonuclease E activity
EBA03_RS11320	COG1054	Belongs to the UPF0176 family
EBA03_RS11340	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EBA03_RS11380	COG0322	excinuclease ABC activity
EBA03_RS11390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBA03_RS11400	COG1663	tetraacyldisaccharide 4'-kinase activity
EBA03_RS11415	COG0811	peptide transport
EBA03_RS11440	COG4591	ABC-type transport system involved in lipoprotein release permease component
EBA03_RS11455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EBA03_RS11470	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EBA03_RS11485	COG0354	folic acid binding
EBA03_RS11500	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA03_RS11510	COG0363	glucosamine-6-phosphate deaminase activity
EBA03_RS11515	COG0129	dihydroxy-acid dehydratase activity
EBA03_RS11520	COG0800	Aldolase
EBA03_RS11595	COG0784	Response regulator, receiver
EBA03_RS11595	COG2205	protein histidine kinase activity
EBA03_RS11610	COG2183	response to ionizing radiation
EBA03_RS11620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA03_RS11620	COG0723	plastoquinol--plastocyanin reductase activity
EBA03_RS11635	COG3243	poly(R)-hydroxyalkanoic acid synthase
EBA03_RS11645	COG1183	phosphatidylcholine synthase activity
EBA03_RS11650	COG1028	Short-chain dehydrogenase reductase Sdr
EBA03_RS11665	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EBA03_RS11675	COG0668	transmembrane transport
EBA03_RS11695	COG1914	H( )-stimulated, divalent metal cation uptake system
EBA03_RS11725	COG0583	DNA-binding transcription factor activity
EBA03_RS11750	COG0583	DNA-binding transcription factor activity
EBA03_RS11755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA03_RS11760	COG3002	Belongs to the UPF0753 family
EBA03_RS11765	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA03_RS11765	COG0519	Catalyzes the synthesis of GMP from XMP
EBA03_RS11775	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EBA03_RS11790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EBA03_RS11800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA03_RS11805	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EBA03_RS11815	COG0776	regulation of translation
EBA03_RS11820	COG0539	negative regulation of cytoplasmic translation
EBA03_RS11825	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EBA03_RS11840	COG2957	Belongs to the agmatine deiminase family
EBA03_RS11850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA03_RS11875	COG0395	ABC-type sugar transport system, permease component
EBA03_RS11880	COG1175	transmembrane transport
EBA03_RS11910	COG2350	Protein conserved in bacteria
EBA03_RS11915	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EBA03_RS11920	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EBA03_RS11925	COG1187	pseudouridine synthase activity
EBA03_RS11945	COG0436	Aminotransferase
EBA03_RS11950	COG4133	protoheme IX ABC transporter activity
EBA03_RS12000	COG1278	Cold shock
EBA03_RS12010	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EBA03_RS12015	COG4988	ABC transporter
EBA03_RS12025	COG1271	oxidase subunit
EBA03_RS12080	COG0165	Argininosuccinate lyase
EBA03_RS12095	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EBA03_RS12100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA03_RS12105	COG0137	argininosuccinate synthase activity
EBA03_RS12110	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EBA03_RS12125	COG2166	iron-sulfur cluster assembly
EBA03_RS12150	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EBA03_RS12165	COG4302	ethanolamine ammonia-lyase activity
EBA03_RS12180	COG4677	pectinesterase activity
EBA03_RS12185	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS12205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EBA03_RS12210	COG0402	S-adenosylhomocysteine deaminase activity
EBA03_RS12230	COG1509	lysine 2,3-aminomutase activity
EBA03_RS12235	COG3300	MHYT domain
EBA03_RS12235	COG5001	Diguanylate cyclase
EBA03_RS12250	COG0483	inositol monophosphate 1-phosphatase activity
EBA03_RS12255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA03_RS12280	COG0488	(ABC) transporter
EBA03_RS12285	COG0513	Belongs to the DEAD box helicase family
EBA03_RS12295	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EBA03_RS12305	COG0625	glutathione transferase activity
EBA03_RS12315	COG1671	Belongs to the UPF0178 family
EBA03_RS12320	COG4681	YaeQ
EBA03_RS12325	COG2081	HI0933 family
EBA03_RS12330	COG5001	Diguanylate cyclase
EBA03_RS12330	COG1716	ATPase activity
EBA03_RS12335	COG0501	Belongs to the peptidase M48B family
EBA03_RS12345	COG1028	Short-chain dehydrogenase reductase Sdr
EBA03_RS12365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EBA03_RS12370	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA03_RS12375	COG0802	atpase or kinase
EBA03_RS12380	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EBA03_RS12380	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EBA03_RS12385	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA03_RS12405	COG3039	Transposase
EBA03_RS12415	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA03_RS12460	COG0835	chemotaxis
EBA03_RS12465	COG0840	transmembrane signaling receptor activity
EBA03_RS12495	COG2969	positive regulation of protein catabolic process
EBA03_RS12500	COG0625	glutathione transferase activity
EBA03_RS12505	COG2857	Cytochrome c1
EBA03_RS12510	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EBA03_RS12515	COG0723	plastoquinol--plastocyanin reductase activity
EBA03_RS12525	COG0741	lytic transglycosylase activity
EBA03_RS12555	COG1702	phosphate starvation-inducible protein PhoH
EBA03_RS12575	COG4535	Mg2 and Co2 transporter CorC
EBA03_RS12590	COG1012	belongs to the aldehyde dehydrogenase family
EBA03_RS12595	COG1177	transmembrane transport
EBA03_RS12600	COG1176	ABC-type spermidine putrescine transport system, permease component I
EBA03_RS12610	COG3842	ATPase activity
EBA03_RS12640	COG3039	Transposase
EBA03_RS12665	COG0174	glutamine synthetase
EBA03_RS12670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA03_RS12680	COG0477	Major facilitator Superfamily
EBA03_RS12690	COG0243	molybdopterin cofactor binding
EBA03_RS12700	COG2223	nitrite transmembrane transporter activity
EBA03_RS12710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EBA03_RS12715	COG1121	(ABC) transporter
EBA03_RS12725	COG2733	membrane
EBA03_RS12730	COG5002	protein histidine kinase activity
EBA03_RS12730	COG0784	Response regulator, receiver
EBA03_RS12730	COG2205	protein histidine kinase activity
EBA03_RS12740	COG3039	Transposase
EBA03_RS12745	COG2902	Dehydrogenase
EBA03_RS12755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA03_RS12760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA03_RS12775	COG1609	Transcriptional regulator
EBA03_RS12780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA03_RS12780	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA03_RS12785	COG1105	Belongs to the carbohydrate kinase PfkB family
EBA03_RS12790	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA03_RS12790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA03_RS12840	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBA03_RS12850	COG1862	Preprotein translocase
EBA03_RS12855	COG0343	queuine tRNA-ribosyltransferase activity
EBA03_RS12920	COG0405	Gamma-glutamyltransferase
EBA03_RS12925	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EBA03_RS12940	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EBA03_RS12945	COG0742	ribosomal rna small subunit methyltransferase
EBA03_RS12950	COG0326	Molecular chaperone. Has ATPase activity
EBA03_RS12995	COG4206	TonB-dependent receptor
EBA03_RS13050	COG0531	amino acid
EBA03_RS13065	COG0006	proline dipeptidase activity
EBA03_RS13075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA03_RS13090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA03_RS13095	COG3938	Belongs to the proline racemase family
EBA03_RS13105	COG0552	protein localization to endoplasmic reticulum
EBA03_RS13120	COG1194	a g-specific adenine glycosylase
EBA03_RS13130	COG0784	Response regulator, receiver
EBA03_RS13130	COG4191	Histidine kinase
EBA03_RS13135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EBA03_RS13160	COG3040	lipid binding
EBA03_RS13170	COG1960	acyl-CoA dehydrogenase activity
EBA03_RS13180	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EBA03_RS13210	COG0438	transferase activity, transferring glycosyl groups
EBA03_RS13220	COG0438	transferase activity, transferring glycosyl groups
EBA03_RS13225	COG0438	transferase activity, transferring glycosyl groups
EBA03_RS13280	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EBA03_RS13295	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EBA03_RS13320	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EBA03_RS13335	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EBA03_RS13340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EBA03_RS13345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EBA03_RS13350	COG3115	cell septum assembly
EBA03_RS13370	COG0360	Binds together with S18 to 16S ribosomal RNA
EBA03_RS13375	COG0316	Belongs to the HesB IscA family
EBA03_RS13410	COG0288	reversible hydration of carbon dioxide
EBA03_RS13435	COG3844	kynureninase activity
EBA03_RS13445	COG2925	Exonuclease
EBA03_RS13455	COG0667	Aldo Keto reductase
EBA03_RS13485	COG0116	Belongs to the methyltransferase superfamily
EBA03_RS13485	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBA03_RS13530	COG0494	nUDIX hydrolase
EBA03_RS13540	COG1024	Enoyl-CoA hydratase
EBA03_RS13550	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EBA03_RS13555	COG0659	secondary active sulfate transmembrane transporter activity
EBA03_RS13580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EBA03_RS13585	COG0573	inorganic phosphate transmembrane transporter activity
EBA03_RS13600	COG0704	Plays a role in the regulation of phosphate uptake
EBA03_RS13610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA03_RS13625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA03_RS13640	COG0557	exoribonuclease II activity
EBA03_RS13670	COG1960	acyl-CoA dehydrogenase activity
EBA03_RS13675	COG2226	methyltransferase
EBA03_RS13680	COG1410	methionine synthase
EBA03_RS13680	COG0646	methionine synthase
EBA03_RS13685	COG0646	methionine synthase
EBA03_RS13685	COG1410	methionine synthase
EBA03_RS13695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA03_RS13705	COG1609	Transcriptional regulator
EBA03_RS13720	COG2900	Belongs to the SlyX family
EBA03_RS13735	COG0386	Belongs to the glutathione peroxidase family
EBA03_RS13745	COG1725	Transcriptional regulator
EBA03_RS13750	COG1131	(ABC) transporter
EBA03_RS13790	COG3039	Transposase
EBA03_RS13820	COG2850	peptidyl-arginine hydroxylation
EBA03_RS13855	COG1132	(ABC) transporter
EBA03_RS13885	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EBA03_RS13895	COG0484	heat shock protein binding
EBA03_RS13900	COG0443	Heat shock 70 kDa protein
EBA03_RS13905	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EBA03_RS13915	COG0497	DNA recombination
EBA03_RS13925	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA03_RS13935	COG2914	Belongs to the UPF0125 (RnfH) family
EBA03_RS13945	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EBA03_RS13970	COG3039	Transposase
EBA03_RS14010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EBA03_RS14025	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EBA03_RS14035	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EBA03_RS14040	COG0174	glutamine synthetase
EBA03_RS14130	COG0415	Belongs to the DNA photolyase family
EBA03_RS14135	COG0305	Participates in initiation and elongation during chromosome replication
EBA03_RS14145	COG0367	asparagine synthase
EBA03_RS14185	COG0084	hydrolase, TatD family'
EBA03_RS14190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EBA03_RS14230	COG0840	transmembrane signaling receptor activity
EBA03_RS14260	COG3039	Transposase
EBA03_RS14275	COG3039	Transposase
EBA03_RS14305	COG0386	Belongs to the glutathione peroxidase family
EBA03_RS14405	COG2814	Major facilitator Superfamily
EBA03_RS14410	COG1566	PFAM secretion protein HlyD family protein
EBA03_RS14425	COG2207	Transcriptional regulator
EBA03_RS14455	COG4774	siderophore transport
EBA03_RS14465	COG0367	asparagine synthase
EBA03_RS14470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA03_RS14480	COG1393	Belongs to the ArsC family
EBA03_RS14540	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EBA03_RS14555	COG0233	cytoplasmic translational termination
EBA03_RS14565	COG0575	Belongs to the CDS family
EBA03_RS14570	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EBA03_RS14575	COG0750	zinc metalloprotease
EBA03_RS14595	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBA03_RS14600	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBA03_RS14620	COG0825	malonyl-CoA metabolic process
EBA03_RS14645	COG1981	membrane
EBA03_RS14695	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA03_RS14710	COG2040	homocysteine
EBA03_RS14715	COG0833	amino acid
EBA03_RS14720	COG0346	lactoylglutathione lyase activity
EBA03_RS14730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBA03_RS14730	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBA03_RS14740	COG2878	Part of a membrane complex involved in electron transport
EBA03_RS14760	COG1595	DNA-templated transcription, initiation
EBA03_RS14785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA03_RS14800	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA03_RS14805	COG0251	oxidation-reduction process
EBA03_RS14815	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EBA03_RS14815	COG0392	lysyltransferase activity
EBA03_RS14855	COG2814	Major facilitator Superfamily
EBA03_RS14860	COG1902	pentaerythritol trinitrate reductase activity
EBA03_RS14875	COG2824	Alkylphosphonate utilization operon protein PhnA
EBA03_RS14885	COG1047	Peptidyl-prolyl cis-trans
EBA03_RS14925	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EBA03_RS14940	COG1451	nucleotide metabolic process
EBA03_RS14960	COG0183	Belongs to the thiolase family
EBA03_RS14990	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EBA03_RS14990	COG1793	dna ligase
EBA03_RS15000	COG1793	dna ligase
EBA03_RS15005	COG1201	RNA secondary structure unwinding
EBA03_RS15025	COG1278	Cold shock
EBA03_RS15030	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EBA03_RS15045	COG3046	protein related to deoxyribodipyrimidine photolyase
EBA03_RS15050	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EBA03_RS15060	COG2954	triphosphatase activity
EBA03_RS15075	COG1381	Involved in DNA repair and RecF pathway recombination
EBA03_RS15105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA03_RS15120	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA03_RS15120	COG1024	Enoyl-CoA hydratase
EBA03_RS15140	COG1024	Enoyl-CoA hydratase
EBA03_RS15145	COG1960	acyl-CoA dehydrogenase activity
EBA03_RS15220	COG2353	YceI-like domain
EBA03_RS15245	COG1760	l-serine dehydratase
EBA03_RS15255	COG0626	cystathionine gamma-synthase activity
EBA03_RS15260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA03_RS15265	COG0739	heme binding
EBA03_RS15275	COG1272	protein, Hemolysin III
EBA03_RS15295	COG0516	GMP reductase activity
EBA03_RS15295	COG0517	IMP dehydrogenase activity
EBA03_RS15300	COG0463	Glycosyl transferase, family 2
EBA03_RS15310	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EBA03_RS15320	COG4771	TonB-dependent receptor
EBA03_RS15325	COG1309	transcriptional regulator
EBA03_RS15335	COG1960	acyl-CoA dehydrogenase activity
EBA03_RS15365	COG0509	glycine decarboxylation via glycine cleavage system
EBA03_RS15380	COG0330	HflC and HflK could
EBA03_RS15390	COG1742	UPF0060 membrane protein
EBA03_RS15395	COG3956	TIGRFAM MazG family protein
EBA03_RS15405	COG0494	nUDIX hydrolase
EBA03_RS15415	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EBA03_RS15420	COG0837	glucose binding
EBA03_RS15435	COG3858	chitin binding
EBA03_RS15435	COG1388	LysM domain
EBA03_RS15455	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA03_RS15495	COG3537	Alpha-1,2-mannosidase
EBA03_RS15540	COG3142	Participates in the control of copper homeostasis
EBA03_RS15545	COG1446	asparaginase
EBA03_RS15555	COG2304	oxidoreductase activity
EBA03_RS15580	COG0784	Response regulator, receiver
EBA03_RS15580	COG2198	Histidine kinase
EBA03_RS15580	COG0643	Histidine kinase
EBA03_RS15585	COG0840	transmembrane signaling receptor activity
EBA03_RS15590	COG0835	chemotaxis
EBA03_RS15605	COG0189	ligase activity
EBA03_RS15615	COG1397	ADP-ribosylglycohydrolase
EBA03_RS15625	COG1199	ATP-dependent helicase activity
EBA03_RS15635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EBA03_RS15640	COG1215	transferase activity, transferring glycosyl groups
EBA03_RS15650	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA03_RS15700	COG1643	Atp-dependent helicase
EBA03_RS15705	COG0783	Belongs to the Dps family
EBA03_RS15715	COG0514	ATP-dependent DNA helicase (RecQ)
EBA03_RS15730	COG3039	Transposase
EBA03_RS15745	COG1187	pseudouridine synthase activity
EBA03_RS15785	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EBA03_RS15795	COG0602	queuosine metabolic process
EBA03_RS15805	COG2885	chlorophyll binding
EBA03_RS15810	COG0823	Involved in the tonB-independent uptake of proteins
EBA03_RS15820	COG0848	biopolymer transport protein
EBA03_RS15830	COG0824	Thioesterase
EBA03_RS15835	COG2255	four-way junction helicase activity
EBA03_RS15850	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EBA03_RS15875	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EBA03_RS15890	COG0477	Major facilitator Superfamily
EBA03_RS15925	COG0488	(ABC) transporter
EBA03_RS15955	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EBA03_RS15955	COG4651	solute:proton antiporter activity
EBA03_RS16000	COG4772	TonB-dependent receptor
EBA03_RS16010	COG4264	IucA IucC family
EBA03_RS16015	COG2814	Major facilitator Superfamily
EBA03_RS16025	COG0019	diaminopimelate decarboxylase activity
EBA03_RS16080	COG4206	TonB-dependent receptor
EBA03_RS16110	COG0542	response to heat
EBA03_RS16135	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EBA03_RS16145	COG0534	Mate efflux family protein
EBA03_RS16160	COG0336	Belongs to the RNA methyltransferase TrmD family
EBA03_RS16165	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EBA03_RS16170	COG0228	four-way junction DNA binding
EBA03_RS16195	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EBA03_RS16205	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA03_RS16245	COG2172	sigma factor antagonist activity
EBA03_RS16250	COG1366	Belongs to the anti-sigma-factor antagonist family
EBA03_RS16255	COG1366	Belongs to the anti-sigma-factor antagonist family
EBA03_RS16265	COG0326	Molecular chaperone. Has ATPase activity
EBA03_RS16270	COG2207	Transcriptional regulator
EBA03_RS16310	COG2963	transposase activity
EBA03_RS16320	COG3039	Transposase
EBA03_RS16340	COG3209	COG3209 Rhs family protein
EBA03_RS16360	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EBA03_RS16365	COG1845	cytochrome c oxidase, subunit III
EBA03_RS16370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EBA03_RS16385	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EBA03_RS16390	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EBA03_RS16405	COG0728	peptidoglycan biosynthetic process
EBA03_RS16410	COG0268	Binds directly to 16S ribosomal RNA
EBA03_RS16415	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EBA03_RS16420	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EBA03_RS16430	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EBA03_RS16435	COG0824	Thioesterase
EBA03_RS16450	COG1946	Acyl-CoA thioesterase
EBA03_RS16460	COG1595	DNA-templated transcription, initiation
EBA03_RS16475	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EBA03_RS16515	COG1877	trehalose-phosphatase activity
EBA03_RS16520	COG3387	PFAM Glycoside hydrolase 15-related
EBA03_RS16560	COG0564	pseudouridine synthase activity
EBA03_RS16565	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA03_RS16570	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EBA03_RS16570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA03_RS16585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EBA03_RS16590	COG0045	succinate-CoA ligase (ADP-forming) activity
EBA03_RS16630	COG2194	sulfuric ester hydrolase activity
EBA03_RS16635	COG4969	Belongs to the N-Me-Phe pilin family
EBA03_RS16645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EBA03_RS16650	COG0237	dephospho-CoA kinase activity
EBA03_RS16655	COG2205	protein histidine kinase activity
EBA03_RS16660	COG0745	RESPONSE REGULATOR receiver
EBA03_RS16680	COG3039	Transposase
EBA03_RS16705	COG3039	Transposase
EBA03_RS16740	COG3039	Transposase
EBA03_RS16765	COG2022	thiamine diphosphate biosynthetic process
EBA03_RS16780	COG3273	potassium ion transport
EBA03_RS16780	COG0471	metal ion transport
EBA03_RS16810	COG1970	mechanosensitive ion channel activity
EBA03_RS16845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA03_RS16860	COG0308	aminopeptidase N
EBA03_RS16865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA03_RS16875	COG0529	Catalyzes the synthesis of activated sulfate
EBA03_RS16875	COG2895	sulfate adenylyltransferase (ATP) activity
EBA03_RS16880	COG0175	sulfate reduction
EBA03_RS16885	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA03_RS16890	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EBA03_RS16895	COG0175	sulfate reduction
EBA03_RS16915	COG2198	Histidine kinase
EBA03_RS16915	COG0784	Response regulator, receiver
EBA03_RS16915	COG2205	protein histidine kinase activity
EBA03_RS16955	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EBA03_RS16960	COG3588	fructose-bisphosphate aldolase
EBA03_RS16970	COG0469	pyruvate kinase activity
EBA03_RS16995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EBA03_RS17005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA03_RS17005	COG3453	Protein conserved in bacteria
EBA03_RS17010	COG0725	ABC transporter, periplasmic molybdate-binding protein
EBA03_RS17015	COG4149	molybdate abc transporter
EBA03_RS17020	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EBA03_RS17040	COG0642	Histidine kinase
EBA03_RS17055	COG1028	Short-chain dehydrogenase reductase Sdr
EBA03_RS17065	COG1022	Amp-dependent synthetase and ligase
EBA03_RS17090	COG1376	ErfK ybiS ycfS ynhG family protein
EBA03_RS17095	COG0739	heme binding
EBA03_RS17110	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EBA03_RS17115	COG1301	dicarboxylic acid transport
EBA03_RS17135	COG2304	oxidoreductase activity
EBA03_RS17155	COG0714	Associated with various cellular activities
EBA03_RS17190	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EBA03_RS17225	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EBA03_RS17235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA03_RS17255	COG1561	YicC-like family, N-terminal region
EBA03_RS17260	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EBA03_RS17275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EBA03_RS17305	COG0006	proline dipeptidase activity
EBA03_RS17330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EBA03_RS17350	COG2912	Transglutaminase-like superfamily
EBA03_RS17355	COG1773	rubredoxin
EBA03_RS17360	COG0352	thiamine-phosphate diphosphorylase activity
EBA03_RS17370	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EBA03_RS17385	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EBA03_RS17430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EBA03_RS17455	COG0671	phosphoesterase, PA-phosphatase related
EBA03_RS17470	COG3781	membrane
EBA03_RS17480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBA03_RS17495	COG3039	Transposase
EBA03_RS17510	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EBA03_RS17520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EBA03_RS17545	COG3710	Transcriptional regulator
EBA03_RS17550	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EBA03_RS17560	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EBA03_RS17590	COG2226	methyltransferase
EBA03_RS17595	COG0066	3-isopropylmalate dehydratase activity
EBA03_RS17600	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EBA03_RS17620	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBA03_RS17625	COG1538	Outer membrane efflux protein
EBA03_RS17630	COG1519	Transferase
EBA03_RS17635	COG1560	Kdo2-lipid A biosynthetic process
EBA03_RS17660	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS17685	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS17730	COG0281	malic enzyme
EBA03_RS17730	COG0280	phosphate acetyltransferase
EBA03_RS17750	COG4191	Histidine kinase
EBA03_RS17765	COG0583	DNA-binding transcription factor activity
EBA03_RS17785	COG2197	response regulator
EBA03_RS17795	COG0642	Histidine kinase
EBA03_RS17815	COG2851	Citrate transporter
EBA03_RS17820	COG1028	Short-chain dehydrogenase reductase Sdr
EBA03_RS17830	COG1609	Transcriptional regulator
EBA03_RS17835	COG2211	Major facilitator Superfamily
EBA03_RS17865	COG0436	Aminotransferase
EBA03_RS17885	COG0726	polysaccharide deacetylase
EBA03_RS17890	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA03_RS17910	COG0402	S-adenosylhomocysteine deaminase activity
EBA03_RS17960	COG0242	peptide deformylase activity
EBA03_RS17965	COG3039	Transposase
EBA03_RS17995	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EBA03_RS18055	COG2188	Transcriptional regulator
EBA03_RS18070	COG1450	Type ii and iii secretion system protein
EBA03_RS18085	COG3166	PFAM Fimbrial assembly family protein
EBA03_RS18090	COG3156	type II secretion system protein K
EBA03_RS18095	COG4795	General secretion pathway protein
EBA03_RS18100	COG2165	general secretion pathway protein
EBA03_RS18105	COG4970	Tfp pilus assembly protein FimT
EBA03_RS18110	COG2165	general secretion pathway protein
EBA03_RS18115	COG1459	type II secretion system
EBA03_RS18125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA03_RS18130	COG1404	Belongs to the peptidase S8 family
EBA03_RS18135	COG5295	Hep Hag repeat protein
EBA03_RS18145	COG0047	phosphoribosylformylglycinamidine synthase activity
EBA03_RS18145	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBA03_RS18155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EBA03_RS18160	COG4974	Belongs to the 'phage' integrase family
EBA03_RS18175	COG0795	lipopolysaccharide-transporting ATPase activity
EBA03_RS18185	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBA03_RS18210	COG0525	valine-tRNA ligase activity
EBA03_RS18240	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS18250	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS18275	COG1183	phosphatidylcholine synthase activity
EBA03_RS18285	COG0442	prolyl-tRNA aminoacylation
EBA03_RS18300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA03_RS18305	COG1127	ABC transporter
EBA03_RS18310	COG3218	ABC-type transport auxiliary lipoprotein component
EBA03_RS18310	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA03_RS18355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBA03_RS18360	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EBA03_RS18360	COG0662	Cupin 2, conserved barrel domain protein
EBA03_RS18390	COG2086	electron transfer activity
EBA03_RS18470	COG0626	cystathionine gamma-synthase activity
EBA03_RS18500	COG0625	glutathione transferase activity
EBA03_RS18515	COG0513	Belongs to the DEAD box helicase family
EBA03_RS18525	COG0720	synthase
EBA03_RS18535	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EBA03_RS18540	COG1956	GAF domain-containing protein
EBA03_RS18550	COG3039	Transposase
EBA03_RS18555	COG0546	phosphoglycolate phosphatase activity
EBA03_RS18585	COG0339	signal peptide processing
EBA03_RS18640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA03_RS18700	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EBA03_RS18705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EBA03_RS18710	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EBA03_RS18720	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EBA03_RS18730	COG0356	it plays a direct role in the translocation of protons across the membrane
EBA03_RS18750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EBA03_RS18760	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBA03_RS18795	COG2011	ABC-type metal ion transport system permease component
EBA03_RS18805	COG0697	spore germination
EBA03_RS18840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EBA03_RS18845	COG1187	pseudouridine synthase activity
EBA03_RS18850	COG2813	Specifically methylates the guanine in position
EBA03_RS18880	COG2202	Pas domain
EBA03_RS18880	COG2205	protein histidine kinase activity
EBA03_RS18905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA03_RS18955	COG0745	RESPONSE REGULATOR receiver
EBA03_RS18970	COG1404	Belongs to the peptidase S8 family
EBA03_RS18985	COG0842	Transport permease protein
EBA03_RS18990	COG1131	(ABC) transporter
EBA03_RS18995	COG0025	NhaP-type Na H and K H
EBA03_RS19005	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EBA03_RS19015	COG1573	uracil-dna glycosylase
EBA03_RS19025	COG3384	dioxygenase
EBA03_RS19040	COG0667	Aldo Keto reductase
EBA03_RS19050	COG3590	peptidase
EBA03_RS19070	COG0531	amino acid
EBA03_RS19095	COG3685	Protein conserved in bacteria
EBA03_RS19100	COG3546	catalase activity
EBA03_RS19125	COG3039	Transposase
EBA03_RS19155	COG1271	oxidase subunit
EBA03_RS19160	COG1294	oxidase, subunit
EBA03_RS19190	COG1063	alcohol dehydrogenase
EBA03_RS19285	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EBA03_RS19285	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EBA03_RS19295	COG1473	amidohydrolase
EBA03_RS19300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA03_RS19305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA03_RS19330	COG5383	Protein conserved in bacteria
EBA03_RS19385	COG3023	N-Acetylmuramoyl-L-alanine amidase
EBA03_RS19395	COG4948	Mandelate Racemase Muconate Lactonizing
EBA03_RS19425	COG0531	amino acid
EBA03_RS19445	COG4682	membrane
EBA03_RS19450	COG2133	pyrroloquinoline quinone binding
EBA03_RS19470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EBA03_RS19475	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EBA03_RS19485	COG1610	YqeY-like protein
EBA03_RS19505	COG1295	ribonuclease BN
EBA03_RS19510	COG0358	DNA primase activity
EBA03_RS19580	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EBA03_RS19595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EBA03_RS19660	COG0739	heme binding
EBA03_RS19675	COG2211	Major facilitator Superfamily
EBA03_RS19680	COG0708	Exodeoxyribonuclease III
EBA03_RS19695	COG1192	Involved in chromosome partitioning
EBA03_RS19700	COG1475	DNA binding
EBA03_RS19720	COG0463	Glycosyl transferase, family 2
EBA03_RS19745	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EBA03_RS19770	COG4221	oxidoreductase activity
EBA03_RS19810	COG1166	arginine decarboxylase activity
EBA03_RS19815	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EBA03_RS19860	COG0606	chelatase, subunit chli
EBA03_RS19885	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EBA03_RS19905	COG3039	Transposase
EBA03_RS19965	COG1090	epimerase
EBA03_RS19975	COG0642	Histidine kinase
EBA03_RS19990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA03_RS20025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBA03_RS20035	COG1595	DNA-templated transcription, initiation
EBA03_RS20040	COG0753	catalase activity
EBA03_RS20065	COG0697	spore germination
EBA03_RS20090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA03_RS20095	COG0180	Tryptophanyl-tRNA synthetase
EBA03_RS20100	COG3237	CsbD-like
EBA03_RS20115	COG0010	Belongs to the arginase family
EBA03_RS20135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EBA03_RS20150	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EBA03_RS20155	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EBA03_RS20155	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EBA03_RS20165	COG3228	Belongs to the MtfA family
EBA03_RS20195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA03_RS20250	COG3039	Transposase
EBA03_RS20255	COG1566	PFAM secretion protein HlyD family protein
EBA03_RS20270	COG1199	ATP-dependent helicase activity
EBA03_RS20315	COG0583	DNA-binding transcription factor activity
EBA03_RS20375	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS20410	COG4555	ABC transporter
EBA03_RS20420	COG1476	TRANSCRIPTIONal
EBA03_RS20440	COG1230	cation diffusion facilitator family transporter
EBA03_RS20445	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA03_RS20450	COG1131	(ABC) transporter
EBA03_RS20455	COG0842	Transport permease protein
EBA03_RS20465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EBA03_RS20500	COG3039	Transposase
EBA03_RS20525	COG2951	lytic endotransglycosylase activity
EBA03_RS20545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA03_RS20555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA03_RS20570	COG0045	succinate-CoA ligase (ADP-forming) activity
EBA03_RS20570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EBA03_RS20570	COG1042	CoA-binding domain protein
EBA03_RS20580	COG2239	Acts as a magnesium transporter
EBA03_RS20605	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA03_RS20610	COG3387	PFAM Glycoside hydrolase 15-related
EBA03_RS20625	COG3100	YcgL domain-containing protein
EBA03_RS20630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EBA03_RS20640	COG0463	Glycosyl transferase, family 2
EBA03_RS20655	COG1028	Short-chain dehydrogenase reductase Sdr
EBA03_RS20685	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBA03_RS20700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBA03_RS20750	COG0408	coproporphyrinogen oxidase activity
EBA03_RS20830	COG0210	DNA helicase
EBA03_RS20850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA03_RS20865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EBA03_RS20880	COG2159	amidohydrolase
EBA03_RS20910	COG0357	Ribosomal RNA small subunit methyltransferase G
EBA03_RS20915	COG3540	Alkaline phosphatase
EBA03_RS20925	COG2091	lysine biosynthetic process via aminoadipic acid
EBA03_RS20940	COG0708	Exodeoxyribonuclease III
EBA03_RS20955	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EBA03_RS20960	COG3162	membrane
EBA03_RS21015	COG1028	Short-chain dehydrogenase reductase Sdr
EBA03_RS21020	COG0179	Fumarylacetoacetate (FAA) hydrolase
EBA03_RS21030	COG4948	Mandelate Racemase Muconate Lactonizing
EBA03_RS21040	COG3039	Transposase
EBA03_RS21045	COG3254	rhamnose metabolic process
EBA03_RS21050	COG0738	Major facilitator superfamily
EBA03_RS21055	COG1414	Transcriptional regulator
EBA03_RS21065	COG2205	protein histidine kinase activity
EBA03_RS21075	COG3459	Glycosyltransferase 36 associated
EBA03_RS21080	COG2211	Major facilitator Superfamily
EBA03_RS21085	COG3265	gluconokinase activity
EBA03_RS21090	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA03_RS21120	COG3039	Transposase
EBA03_RS21130	COG3039	Transposase
EBA03_RS21135	COG2911	Protein conserved in bacteria
EBA03_RS21140	COG0729	surface antigen
EBA03_RS21145	COG4771	TonB-dependent receptor
EBA03_RS21150	COG0457	Tetratricopeptide repeat
EBA03_RS21165	COG0752	glycyl-tRNA synthetase alpha subunit
EBA03_RS21170	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA03_RS21180	COG0519	Catalyzes the synthesis of GMP from XMP
EBA03_RS21180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA03_RS21190	COG0805	protein transport
EBA03_RS21195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA03_RS21200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA03_RS21210	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EBA03_RS21240	COG2974	May be involved in recombination
EBA03_RS21245	COG0037	tRNA processing
EBA03_RS21270	COG3661	Belongs to the glycosyl hydrolase 67 family
EBA03_RS21280	COG4948	Mandelate Racemase Muconate Lactonizing
EBA03_RS21290	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA03_RS21295	COG0246	Mannitol dehydrogenase
EBA03_RS21330	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS21355	COG3693	PFAM glycoside hydrolase, family 10
EBA03_RS21380	COG2211	Major facilitator Superfamily
EBA03_RS21395	COG3039	Transposase
EBA03_RS21425	COG2937	Belongs to the GPAT DAPAT family
EBA03_RS21470	COG0284	orotidine-5'-phosphate decarboxylase activity
EBA03_RS21475	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EBA03_RS21480	COG3132	Protein of unknown function, DUF480
EBA03_RS21495	COG0210	DNA helicase
EBA03_RS21510	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EBA03_RS21520	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EBA03_RS21575	COG0676	glucose-6-phosphate 1-epimerase activity
EBA03_RS21590	COG0730	response to heat
EBA03_RS21625	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EBA03_RS21630	COG0302	gtp cyclohydrolase
EBA03_RS21660	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS21670	COG0477	Major facilitator Superfamily
EBA03_RS21685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA03_RS21730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA03_RS21790	COG3237	CsbD-like
EBA03_RS21830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA03_RS21860	COG1304	FMN binding
EBA03_RS21885	COG4772	TonB-dependent receptor
EBA03_RS21895	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EBA03_RS21925	COG3039	Transposase
EBA03_RS21990	COG0564	pseudouridine synthase activity
EBA03_RS22005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA03_RS22065	COG3039	Transposase
EBA03_RS22090	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS22155	COG1074	ATP-dependent DNA helicase activity
EBA03_RS22160	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EBA03_RS22165	COG1116	anion transmembrane transporter activity
EBA03_RS22175	COG3039	Transposase
EBA03_RS22180	COG3039	Transposase
EBA03_RS22190	COG1136	(ABC) transporter
EBA03_RS22210	COG1127	ABC transporter
EBA03_RS22215	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA03_RS22220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA03_RS22235	COG2853	Lipoprotein
EBA03_RS22245	COG2826	transposase and inactivated derivatives, IS30 family
EBA03_RS22260	COG0386	Belongs to the glutathione peroxidase family
EBA03_RS22270	COG1322	Protein conserved in bacteria
EBA03_RS22275	COG3039	Transposase
EBA03_RS22300	COG1929	Belongs to the glycerate kinase type-1 family
EBA03_RS22305	COG2271	Major facilitator Superfamily
EBA03_RS22320	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBA03_RS22330	COG0861	Integral membrane protein TerC family
EBA03_RS22340	COG0584	glycerophosphoryl diester phosphodiesterase
EBA03_RS22350	COG0671	phosphoesterase, PA-phosphatase related
EBA03_RS22355	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EBA03_RS22360	COG0726	polysaccharide deacetylase