locus-tag	class	description
EBA08_RS00025	COG0187	DNA topoisomerase II activity
EBA08_RS00035	COG0501	Belongs to the peptidase M48B family
EBA08_RS00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EBA08_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA08_RS00095	COG3039	Transposase
EBA08_RS00145	COG0793	Belongs to the peptidase S41A family
EBA08_RS00150	COG4942	peptidase
EBA08_RS00160	COG2234	aminopeptidase activity
EBA08_RS00170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA08_RS00185	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA08_RS00195	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA08_RS00205	COG1064	alcohol dehydrogenase
EBA08_RS00235	COG0493	'glutamate synthase
EBA08_RS00240	COG0070	glutamate synthase
EBA08_RS00240	COG0067	glutamate synthase
EBA08_RS00240	COG0069	glutamate synthase activity
EBA08_RS00310	COG1205	dead DEAH box helicase
EBA08_RS00310	COG1111	helicase
EBA08_RS00315	COG1272	protein, Hemolysin III
EBA08_RS00345	COG2032	superoxide dismutase activity
EBA08_RS00350	COG2204	response regulator
EBA08_RS00355	COG3852	Histidine kinase
EBA08_RS00360	COG0004	ammonium transporteR
EBA08_RS00365	COG0347	Belongs to the P(II) protein family
EBA08_RS00370	COG0174	glutamine synthetase
EBA08_RS00375	COG1968	undecaprenyl-diphosphatase activity
EBA08_RS00425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA08_RS00435	COG2062	phosphohistidine phosphatase, SixA
EBA08_RS00440	COG0489	protein tyrosine kinase activity
EBA08_RS00460	COG1396	sequence-specific DNA binding
EBA08_RS00465	COG3550	peptidyl-serine autophosphorylation
EBA08_RS00470	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EBA08_RS00475	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA08_RS00490	COG1125	glycine betaine transport
EBA08_RS00505	COG1119	ATPase activity
EBA08_RS00520	COG1752	Esterase of the alpha-beta hydrolase superfamily
EBA08_RS00530	COG1522	sequence-specific DNA binding
EBA08_RS00535	COG3186	Phenylalanine-4-hydroxylase
EBA08_RS00565	COG1609	Transcriptional regulator
EBA08_RS00605	COG0366	Alpha amylase catalytic
EBA08_RS00610	COG0366	Alpha amylase catalytic
EBA08_RS00620	COG3039	Transposase
EBA08_RS00670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EBA08_RS00675	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EBA08_RS00690	COG0028	Belongs to the TPP enzyme family
EBA08_RS00695	COG4191	Histidine kinase
EBA08_RS00720	COG3039	Transposase
EBA08_RS00730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EBA08_RS00745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA08_RS00750	COG3177	Filamentation induced by cAMP protein fic
EBA08_RS00755	COG0596	Alpha beta hydrolase
EBA08_RS00765	COG0727	PFAM Uncharacterised protein family (UPF0153)
EBA08_RS00770	COG0318	PFAM AMP-dependent synthetase and ligase
EBA08_RS00775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EBA08_RS00790	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA08_RS00805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBA08_RS00820	COG0564	pseudouridine synthase activity
EBA08_RS00850	COG0339	signal peptide processing
EBA08_RS00895	COG4770	biotin carboxylase activity
EBA08_RS00900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EBA08_RS00905	COG1960	acyl-CoA dehydrogenase activity
EBA08_RS00960	COG0697	spore germination
EBA08_RS00970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EBA08_RS00975	COG1846	Transcriptional regulator
EBA08_RS00980	COG1764	response to oxidative stress
EBA08_RS01030	COG0656	L-ascorbic acid biosynthetic process
EBA08_RS01045	COG2130	NADP-dependent
EBA08_RS01060	COG1187	pseudouridine synthase activity
EBA08_RS01075	COG1643	Atp-dependent helicase
EBA08_RS01085	COG4807	Protein conserved in bacteria
EBA08_RS01090	COG2072	flavoprotein involved in K transport
EBA08_RS01110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EBA08_RS01115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA08_RS01155	COG3039	Transposase
EBA08_RS01200	COG0084	hydrolase, TatD family'
EBA08_RS01220	COG0583	DNA-binding transcription factor activity
EBA08_RS01225	COG2814	Major facilitator Superfamily
EBA08_RS01235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EBA08_RS01240	COG1902	pentaerythritol trinitrate reductase activity
EBA08_RS01270	COG0745	RESPONSE REGULATOR receiver
EBA08_RS01290	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA08_RS01295	COG0583	DNA-binding transcription factor activity
EBA08_RS01325	COG0702	epimerase
EBA08_RS01330	COG1733	regulation of RNA biosynthetic process
EBA08_RS01365	COG3039	Transposase
EBA08_RS01400	COG0129	dihydroxy-acid dehydratase activity
EBA08_RS01410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EBA08_RS01480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EBA08_RS01485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EBA08_RS01495	COG3485	protocatechuate 3,4-dioxygenase
EBA08_RS01500	COG3485	protocatechuate 3,4-dioxygenase
EBA08_RS01515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA08_RS01520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EBA08_RS01535	COG1414	Transcriptional regulator
EBA08_RS01575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EBA08_RS01615	COG0156	8-amino-7-oxononanoate synthase activity
EBA08_RS01620	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EBA08_RS01625	COG1040	competence protein
EBA08_RS01630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EBA08_RS01735	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EBA08_RS01810	COG3264	Mechanosensitive ion channel
EBA08_RS01810	COG1511	domain protein
EBA08_RS01820	COG3039	Transposase
EBA08_RS01825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBA08_RS01835	COG2354	Protein conserved in bacteria
EBA08_RS01860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EBA08_RS01885	COG0702	epimerase
EBA08_RS01895	COG1028	Short-chain dehydrogenase reductase Sdr
EBA08_RS01940	COG0513	Belongs to the DEAD box helicase family
EBA08_RS01950	COG3039	Transposase
EBA08_RS01980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EBA08_RS01990	COG3483	tryptophan 2,3-dioxygenase activity
EBA08_RS01995	COG3104	oligopeptide transport
EBA08_RS02015	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EBA08_RS02025	COG1320	monovalent cation:proton antiporter activity
EBA08_RS02030	COG2212	antiporter activity
EBA08_RS02040	COG0651	ATP synthesis coupled electron transport
EBA08_RS02045	COG1006	Multisubunit Na H antiporter MnhC subunit
EBA08_RS02050	COG2111	Na H antiporter
EBA08_RS02050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA08_RS02085	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EBA08_RS02095	COG0456	acetyltransferase
EBA08_RS02135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EBA08_RS02140	COG0134	indole-3-glycerol-phosphate synthase activity
EBA08_RS02150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EBA08_RS02155	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EBA08_RS02165	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EBA08_RS02170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EBA08_RS02175	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EBA08_RS02245	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EBA08_RS02265	COG2814	Major facilitator Superfamily
EBA08_RS02275	COG2814	Major facilitator Superfamily
EBA08_RS02280	COG1289	transmembrane transporter activity
EBA08_RS02290	COG0151	Belongs to the GarS family
EBA08_RS02300	COG0138	bifunctional purine biosynthesis protein purh
EBA08_RS02305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EBA08_RS02315	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EBA08_RS02370	COG0439	Biotin carboxylase
EBA08_RS02380	COG0511	ligase activity, forming carbon-carbon bonds
EBA08_RS02385	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EBA08_RS02400	COG1324	tolerance protein
EBA08_RS02420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EBA08_RS02440	COG0534	Mate efflux family protein
EBA08_RS02445	COG0616	signal peptide processing
EBA08_RS02455	COG1028	Short-chain dehydrogenase reductase Sdr
EBA08_RS02470	COG0009	L-threonylcarbamoyladenylate synthase
EBA08_RS02475	COG1754	DNA topoisomerase type I activity
EBA08_RS02475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA08_RS02495	COG0758	DNA mediated transformation
EBA08_RS02500	COG1652	LysM domain
EBA08_RS02505	COG0242	peptide deformylase activity
EBA08_RS02510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EBA08_RS02515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBA08_RS02515	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EBA08_RS02565	COG1560	Kdo2-lipid A biosynthetic process
EBA08_RS02575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA08_RS02605	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EBA08_RS02610	COG3118	belongs to the thioredoxin family
EBA08_RS02620	COG2884	Cell division ATP-binding protein ftsE
EBA08_RS02625	COG2177	Part of the ABC transporter FtsEX involved in
EBA08_RS02630	COG3437	response regulator, receiver
EBA08_RS02635	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EBA08_RS02640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA08_RS02645	COG2860	membrane
EBA08_RS02650	COG1252	NADH dehydrogenase
EBA08_RS02675	COG0459	protein refolding
EBA08_RS02690	COG3039	Transposase
EBA08_RS02700	COG3039	Transposase
EBA08_RS02710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EBA08_RS02725	COG3386	PFAM SMP-30 Gluconolaconase
EBA08_RS02740	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA08_RS02785	COG2353	YceI-like domain
EBA08_RS02905	COG4221	oxidoreductase activity
EBA08_RS02960	COG0697	spore germination
EBA08_RS02965	COG4305	rare lipoprotein A
EBA08_RS02970	COG5297	Belongs to the glycosyl hydrolase family 6
EBA08_RS02980	COG1113	amino acid transport
EBA08_RS02990	COG0598	Magnesium transport protein CorA
EBA08_RS03070	COG3300	MHYT domain
EBA08_RS03070	COG5001	Diguanylate cyclase
EBA08_RS03095	COG5297	Belongs to the glycosyl hydrolase family 6
EBA08_RS03095	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA08_RS03100	COG0659	secondary active sulfate transmembrane transporter activity
EBA08_RS03135	COG3275	phosphorelay sensor kinase activity
EBA08_RS03145	COG0181	hydroxymethylbilane synthase activity
EBA08_RS03170	COG1505	serine-type exopeptidase activity
EBA08_RS03180	COG0436	Aminotransferase
EBA08_RS03190	COG2832	Protein of unknown function (DUF454)
EBA08_RS03210	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EBA08_RS03220	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EBA08_RS03255	COG3300	MHYT domain
EBA08_RS03255	COG5001	Diguanylate cyclase
EBA08_RS03260	COG0308	aminopeptidase N
EBA08_RS03275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA08_RS03280	COG1077	Cell shape determining protein MreB Mrl
EBA08_RS03285	COG1792	Involved in formation and maintenance of cell shape
EBA08_RS03300	COG0772	Belongs to the SEDS family
EBA08_RS03325	COG2951	lytic endotransglycosylase activity
EBA08_RS03330	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EBA08_RS03335	COG1686	Belongs to the peptidase S11 family
EBA08_RS03350	COG2921	Belongs to the UPF0250 family
EBA08_RS03375	COG1051	belongs to the nudix hydrolase family
EBA08_RS03375	COG1056	cytidyltransferase-related domain
EBA08_RS03410	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EBA08_RS03415	COG0673	inositol 2-dehydrogenase activity
EBA08_RS03420	COG2823	Periplasmic or secreted lipoprotein
EBA08_RS03425	COG4251	negative regulation of phosphorylation
EBA08_RS03430	COG0784	Response regulator, receiver
EBA08_RS03435	COG4191	Histidine kinase
EBA08_RS03440	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EBA08_RS03465	COG3039	Transposase
EBA08_RS03485	COG3250	beta-galactosidase activity
EBA08_RS03500	COG2188	Transcriptional regulator
EBA08_RS03510	COG1609	Transcriptional regulator
EBA08_RS03515	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA08_RS03520	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EBA08_RS03535	COG1215	transferase activity, transferring glycosyl groups
EBA08_RS03540	COG1649	PFAM Uncharacterised BCR, COG1649
EBA08_RS03540	COG0726	polysaccharide deacetylase
EBA08_RS03565	COG3039	Transposase
EBA08_RS03610	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EBA08_RS03650	COG2205	protein histidine kinase activity
EBA08_RS03680	COG3791	Glutathione-dependent formaldehyde-activating
EBA08_RS03695	COG3039	Transposase
EBA08_RS03710	COG0488	(ABC) transporter
EBA08_RS03730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EBA08_RS03740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EBA08_RS03750	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA08_RS03750	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA08_RS03770	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EBA08_RS03775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBA08_RS03780	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EBA08_RS03805	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EBA08_RS03810	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EBA08_RS03820	COG2205	protein histidine kinase activity
EBA08_RS03825	COG0745	RESPONSE REGULATOR receiver
EBA08_RS03855	COG0277	FAD linked oxidase domain protein
EBA08_RS03865	COG0792	nuclease activity
EBA08_RS03905	COG0275	rRNA processing
EBA08_RS03910	COG3116	cell division
EBA08_RS03925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EBA08_RS03930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA08_RS03945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBA08_RS03950	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA08_RS03955	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EBA08_RS03970	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EBA08_RS03980	COG0739	heme binding
EBA08_RS03980	COG1196	nuclear chromosome segregation
EBA08_RS03980	COG0741	lytic transglycosylase activity
EBA08_RS03995	COG0494	nUDIX hydrolase
EBA08_RS04010	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EBA08_RS04025	COG0604	alcohol dehydrogenase
EBA08_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
EBA08_RS04025	COG3321	synthase
EBA08_RS04085	COG2226	methyltransferase
EBA08_RS04090	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EBA08_RS04115	COG2826	transposase and inactivated derivatives, IS30 family
EBA08_RS04140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EBA08_RS04155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA08_RS04165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA08_RS04170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EBA08_RS04180	COG0667	Aldo Keto reductase
EBA08_RS04205	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EBA08_RS04215	COG2175	clavaminate synthase activity
EBA08_RS04225	COG4181	ATPase activity
EBA08_RS04240	COG0642	Histidine kinase
EBA08_RS04255	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EBA08_RS04275	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EBA08_RS04295	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EBA08_RS04300	COG2967	ApaG domain
EBA08_RS04305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EBA08_RS04320	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EBA08_RS04335	COG0123	including yeast histone deacetylase and acetoin utilization protein
EBA08_RS04340	COG2096	Adenosyltransferase
EBA08_RS04355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA08_RS04360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA08_RS04380	COG1802	Transcriptional regulator
EBA08_RS04390	COG3384	dioxygenase
EBA08_RS04395	COG0583	DNA-binding transcription factor activity
EBA08_RS04400	COG0318	PFAM AMP-dependent synthetase and ligase
EBA08_RS04410	COG1024	Enoyl-CoA hydratase
EBA08_RS04430	COG3386	PFAM SMP-30 Gluconolaconase
EBA08_RS04480	COG2197	response regulator
EBA08_RS04490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EBA08_RS04495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EBA08_RS04500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA08_RS04510	COG0583	DNA-binding transcription factor activity
EBA08_RS04515	COG3634	alkyl hydroperoxide reductase activity
EBA08_RS04525	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA08_RS04565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA08_RS04565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA08_RS04580	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBA08_RS04635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EBA08_RS04645	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EBA08_RS04675	COG1295	ribonuclease BN
EBA08_RS04680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA08_RS04685	COG1254	Belongs to the acylphosphatase family
EBA08_RS04700	COG0521	Mo-molybdopterin cofactor biosynthetic process
EBA08_RS04710	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EBA08_RS04715	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EBA08_RS04725	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EBA08_RS04740	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EBA08_RS04750	COG0193	aminoacyl-tRNA hydrolase activity
EBA08_RS04755	COG0012	GTP binding
EBA08_RS04790	COG0250	Participates in transcription elongation, termination and antitermination
EBA08_RS04800	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EBA08_RS04805	COG0081	regulation of translation
EBA08_RS04810	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EBA08_RS04820	COG0085	RNA polymerase activity
EBA08_RS04825	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EBA08_RS04830	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EBA08_RS04835	COG0049	tRNA binding
EBA08_RS04865	COG0088	Forms part of the polypeptide exit tunnel
EBA08_RS04870	COG0089	rRNA binding
EBA08_RS04875	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EBA08_RS04885	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EBA08_RS04895	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EBA08_RS04900	COG0255	Belongs to the universal ribosomal protein uL29 family
EBA08_RS04905	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EBA08_RS04910	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EBA08_RS04915	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EBA08_RS04950	COG1841	ribosomal large subunit assembly
EBA08_RS04955	COG0200	Binds to the 23S rRNA
EBA08_RS04960	COG0201	protein transport
EBA08_RS04970	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EBA08_RS04975	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EBA08_RS04985	COG0203	ribosomal protein L17
EBA08_RS05005	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EBA08_RS05025	COG1217	gtp-binding protein TYPA
EBA08_RS05030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EBA08_RS05040	COG0625	glutathione transferase activity
EBA08_RS05070	COG3039	Transposase
EBA08_RS05090	COG0446	pyridine nucleotide-disulphide oxidoreductase
EBA08_RS05090	COG1902	pentaerythritol trinitrate reductase activity
EBA08_RS05095	COG0604	alcohol dehydrogenase
EBA08_RS05125	COG0156	8-amino-7-oxononanoate synthase activity
EBA08_RS05130	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EBA08_RS05135	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EBA08_RS05140	COG4208	sulfate ABC transporter
EBA08_RS05145	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EBA08_RS05180	COG0406	alpha-ribazole phosphatase activity
EBA08_RS05190	COG0285	dihydrofolate synthase activity
EBA08_RS05210	COG2833	Protein of unknown function (DUF455)
EBA08_RS05235	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBA08_RS05240	COG0671	phosphoesterase, PA-phosphatase related
EBA08_RS05245	COG0438	transferase activity, transferring glycosyl groups
EBA08_RS05255	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EBA08_RS05260	COG5002	protein histidine kinase activity
EBA08_RS05270	COG4783	chaperone-mediated protein folding
EBA08_RS05285	COG0473	3-isopropylmalate dehydrogenase activity
EBA08_RS05325	COG3039	Transposase
EBA08_RS05350	COG0544	peptidyl-prolyl cis-trans isomerase activity
EBA08_RS05390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EBA08_RS05415	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA08_RS05430	COG0631	protein serine/threonine phosphatase activity
EBA08_RS05465	COG0859	PFAM glycosyl transferase family 9
EBA08_RS05470	COG3642	lipopolysaccharide core region biosynthetic process
EBA08_RS05475	COG1234	tRNA 3'-trailer cleavage
EBA08_RS05480	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EBA08_RS05490	COG0315	cyclic pyranopterin monophosphate synthase activity
EBA08_RS05495	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EBA08_RS05500	COG0314	molybdopterin synthase activity
EBA08_RS05535	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EBA08_RS05545	COG0537	adenosine 5'-monophosphoramidase activity
EBA08_RS05565	COG0714	Associated with various cellular activities
EBA08_RS05585	COG1399	metal-binding, possibly nucleic acid-binding protein
EBA08_RS05610	COG1028	Short-chain dehydrogenase reductase Sdr
EBA08_RS05615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBA08_RS05625	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EBA08_RS05630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EBA08_RS05665	COG3829	transcription factor binding
EBA08_RS05700	COG3039	Transposase
EBA08_RS05780	COG0330	HflC and HflK could
EBA08_RS05785	COG0330	HflC and HflK could
EBA08_RS05795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EBA08_RS05800	COG0308	aminopeptidase N
EBA08_RS05815	COG0732	type I restriction modification DNA specificity domain
EBA08_RS05830	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EBA08_RS05915	COG0587	DNA-directed DNA polymerase activity
EBA08_RS05935	COG1297	OPT oligopeptide transporter protein
EBA08_RS05955	COG1506	peptidase
EBA08_RS05955	COG0823	Involved in the tonB-independent uptake of proteins
EBA08_RS05965	COG2207	Transcriptional regulator
EBA08_RS05965	COG1917	Cupin 2, conserved barrel domain protein
EBA08_RS06010	COG0753	catalase activity
EBA08_RS06050	COG3551	Protein conserved in bacteria
EBA08_RS06080	COG2194	sulfuric ester hydrolase activity
EBA08_RS06090	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EBA08_RS06095	COG0745	RESPONSE REGULATOR receiver
EBA08_RS06100	COG0642	Histidine kinase
EBA08_RS06110	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EBA08_RS06115	COG2894	cell division
EBA08_RS06130	COG4585	Histidine kinase
EBA08_RS06135	COG2197	response regulator
EBA08_RS06150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EBA08_RS06175	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EBA08_RS06250	COG2826	transposase and inactivated derivatives, IS30 family
EBA08_RS06275	COG3039	Transposase
EBA08_RS06300	COG3179	chitinase
EBA08_RS06455	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EBA08_RS06470	COG1842	Phage shock protein A
EBA08_RS06495	COG0754	glutathionylspermidine amidase activity
EBA08_RS06575	COG0531	amino acid
EBA08_RS06580	COG2197	response regulator
EBA08_RS06585	COG2267	carboxylic ester hydrolase activity
EBA08_RS06595	COG1113	amino acid transport
EBA08_RS06625	COG3039	Transposase
EBA08_RS06635	COG1294	oxidase, subunit
EBA08_RS06645	COG2239	Acts as a magnesium transporter
EBA08_RS06655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA08_RS06660	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA08_RS06675	COG3039	Transposase
EBA08_RS06690	COG1660	Displays ATPase and GTPase activities
EBA08_RS06700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA08_RS06715	COG1137	ATPase activity
EBA08_RS06720	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EBA08_RS06730	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EBA08_RS06740	COG0271	Belongs to the BolA IbaG family
EBA08_RS06745	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EBA08_RS06770	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EBA08_RS06785	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EBA08_RS06795	COG0628	permease
EBA08_RS06805	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EBA08_RS06810	COG3178	'Phosphotransferase
EBA08_RS06820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA08_RS06825	COG1555	photosystem II stabilization
EBA08_RS06845	COG3039	Transposase
EBA08_RS06855	COG2146	nitrite reductase [NAD(P)H] activity
EBA08_RS06865	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EBA08_RS06870	COG0719	Fe-S assembly protein
EBA08_RS06875	COG0396	ATPase activity
EBA08_RS06880	COG0719	Fe-S assembly protein
EBA08_RS06885	COG1959	2 iron, 2 sulfur cluster binding
EBA08_RS06940	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EBA08_RS06975	COG0519	Catalyzes the synthesis of GMP from XMP
EBA08_RS06990	COG1678	Uncharacterized ACR, COG1678
EBA08_RS06995	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EBA08_RS07010	COG1764	response to oxidative stress
EBA08_RS07020	COG0384	phenazine biosynthesis protein PhzF
EBA08_RS07030	COG0527	aspartate kinase activity
EBA08_RS07060	COG3039	Transposase
EBA08_RS07070	COG0142	geranyltranstransferase activity
EBA08_RS07075	COG0629	single-stranded DNA binding
EBA08_RS07080	COG4251	negative regulation of phosphorylation
EBA08_RS07080	COG5001	Diguanylate cyclase
EBA08_RS07080	COG3706	GGDEF domain
EBA08_RS07080	COG2203	Gaf domain
EBA08_RS07125	COG2879	small protein
EBA08_RS07130	COG1966	Carbon starvation protein
EBA08_RS07135	COG1741	Belongs to the pirin family
EBA08_RS07230	COG1515	deoxyribonuclease V activity
EBA08_RS07250	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EBA08_RS07255	COG2200	EAL domain
EBA08_RS07255	COG2199	diguanylate cyclase activity
EBA08_RS07255	COG2202	Pas domain
EBA08_RS07260	COG0835	chemotaxis
EBA08_RS07265	COG0840	transmembrane signaling receptor activity
EBA08_RS07275	COG0643	Histidine kinase
EBA08_RS07275	COG2198	Histidine kinase
EBA08_RS07290	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EBA08_RS07300	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EBA08_RS07335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EBA08_RS07340	COG0735	belongs to the Fur family
EBA08_RS07370	COG2826	transposase and inactivated derivatives, IS30 family
EBA08_RS07460	COG3039	Transposase
EBA08_RS07520	COG5002	protein histidine kinase activity
EBA08_RS07520	COG5001	Diguanylate cyclase
EBA08_RS07525	COG1187	pseudouridine synthase activity
EBA08_RS07545	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EBA08_RS07555	COG0475	glutathione-regulated potassium exporter activity
EBA08_RS07560	COG5000	phosphorelay sensor kinase activity
EBA08_RS07560	COG5002	protein histidine kinase activity
EBA08_RS07565	COG0745	RESPONSE REGULATOR receiver
EBA08_RS07570	COG1538	Outer membrane efflux protein
EBA08_RS07595	COG1132	(ABC) transporter
EBA08_RS07620	COG3039	Transposase
EBA08_RS07665	COG3118	belongs to the thioredoxin family
EBA08_RS07695	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EBA08_RS07715	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EBA08_RS07740	COG2968	Membrane
EBA08_RS07755	COG3164	Protein of unknown function
EBA08_RS07765	COG0312	modulator of DNA gyrase
EBA08_RS07770	COG3028	Belongs to the UPF0307 family
EBA08_RS07775	COG0312	modulator of DNA gyrase
EBA08_RS07790	COG4104	PAAR repeat-containing protein
EBA08_RS07800	COG0142	geranyltranstransferase activity
EBA08_RS07805	COG1722	exodeoxyribonuclease VII activity
EBA08_RS07810	COG0037	tRNA processing
EBA08_RS07815	COG1785	Belongs to the alkaline phosphatase family
EBA08_RS07820	COG1301	dicarboxylic acid transport
EBA08_RS07825	COG4106	trans-aconitate 2-methyltransferase activity
EBA08_RS07840	COG0791	NLP P60 protein
EBA08_RS07845	COG0791	NLP P60 protein
EBA08_RS07850	COG1047	Peptidyl-prolyl cis-trans
EBA08_RS07855	COG2311	Membrane
EBA08_RS07860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA08_RS07890	COG3039	Transposase
EBA08_RS07900	COG2826	transposase and inactivated derivatives, IS30 family
EBA08_RS07930	COG2826	transposase and inactivated derivatives, IS30 family
EBA08_RS07935	COG3039	Transposase
EBA08_RS07950	COG0489	protein tyrosine kinase activity
EBA08_RS07960	COG0717	Belongs to the dCTP deaminase family
EBA08_RS07975	COG3039	Transposase
EBA08_RS07995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EBA08_RS08005	COG3039	Transposase
EBA08_RS08015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA08_RS08030	COG2826	transposase and inactivated derivatives, IS30 family
EBA08_RS08040	COG0433	COG0433 Predicted ATPase
EBA08_RS08070	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA08_RS08075	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EBA08_RS08080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBA08_RS08085	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EBA08_RS08105	COG0101	tRNA pseudouridine synthase activity
EBA08_RS08110	COG0135	phosphoribosylanthranilate isomerase activity
EBA08_RS08120	COG0133	tryptophan synthase activity
EBA08_RS08140	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EBA08_RS08145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBA08_RS08200	COG0149	triose-phosphate isomerase activity
EBA08_RS08215	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA08_RS08225	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA08_RS08230	COG0649	NAD binding
EBA08_RS08235	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EBA08_RS08240	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EBA08_RS08245	COG1034	ATP synthesis coupled electron transport
EBA08_RS08250	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EBA08_RS08255	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA08_RS08280	COG1007	ATP synthesis coupled electron transport
EBA08_RS08290	COG0779	Required for maturation of 30S ribosomal subunits
EBA08_RS08295	COG0195	Participates in both transcription termination and antitermination
EBA08_RS08300	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EBA08_RS08315	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EBA08_RS08320	COG1185	polyribonucleotide nucleotidyltransferase activity
EBA08_RS08355	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA08_RS08365	COG2095	MarC family integral membrane protein
EBA08_RS08380	COG3039	Transposase
EBA08_RS08385	COG1611	Belongs to the LOG family
EBA08_RS08425	COG4969	Belongs to the N-Me-Phe pilin family
EBA08_RS08430	COG0556	nucleotide-excision repair
EBA08_RS08460	COG3723	Recombinational DNA repair protein, rece pathway
EBA08_RS08560	COG0270	DNA (cytosine-5-)-methyltransferase activity
EBA08_RS08775	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EBA08_RS08785	COG2986	histidine ammonia-lyase
EBA08_RS08790	COG1228	amidohydrolase
EBA08_RS08835	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EBA08_RS08840	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EBA08_RS08845	COG1605	Chorismate mutase
EBA08_RS08845	COG0077	Prephenate dehydratase
EBA08_RS08850	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EBA08_RS08875	COG3039	Transposase
EBA08_RS08885	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EBA08_RS08900	COG0583	DNA-binding transcription factor activity
EBA08_RS08915	COG2336	PFAM SpoVT AbrB
EBA08_RS08955	COG0840	transmembrane signaling receptor activity
EBA08_RS08980	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EBA08_RS08985	COG4191	Histidine kinase
EBA08_RS08985	COG0784	Response regulator, receiver
EBA08_RS09000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA08_RS09020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA08_RS09035	COG1595	DNA-templated transcription, initiation
EBA08_RS09085	COG2244	polysaccharide biosynthetic process
EBA08_RS09115	COG2264	protein methyltransferase activity
EBA08_RS09125	COG0438	transferase activity, transferring glycosyl groups
EBA08_RS09140	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EBA08_RS09145	COG1132	(ABC) transporter
EBA08_RS09155	COG0477	Major facilitator Superfamily
EBA08_RS09175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBA08_RS09190	COG1253	flavin adenine dinucleotide binding
EBA08_RS09205	COG0306	phosphate transporter
EBA08_RS09235	COG0504	CTP synthase activity
EBA08_RS09240	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EBA08_RS09245	COG0148	phosphopyruvate hydratase activity
EBA08_RS09250	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EBA08_RS09265	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EBA08_RS09275	COG2840	Smr protein MutS2
EBA08_RS09280	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EBA08_RS09285	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBA08_RS09290	COG1238	metal cluster binding
EBA08_RS09305	COG1534	Rna-binding protein
EBA08_RS09310	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EBA08_RS09320	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EBA08_RS09335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EBA08_RS09340	COG1546	Belongs to the CinA family
EBA08_RS09355	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EBA08_RS09365	COG2137	regulation of response to DNA damage stimulus
EBA08_RS09370	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EBA08_RS09375	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EBA08_RS09425	COG1741	Belongs to the pirin family
EBA08_RS09430	COG0583	DNA-binding transcription factor activity
EBA08_RS09455	COG0351	phosphomethylpyrimidine kinase
EBA08_RS09455	COG0352	thiamine-phosphate diphosphorylase activity
EBA08_RS09465	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EBA08_RS09470	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EBA08_RS09485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA08_RS09495	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EBA08_RS09500	COG3734	2-keto-3-deoxy-galactonokinase
EBA08_RS09510	COG4948	Mandelate Racemase Muconate Lactonizing
EBA08_RS09515	COG0800	Aldolase
EBA08_RS09540	COG1070	Carbohydrate kinase
EBA08_RS09550	COG0477	Major facilitator Superfamily
EBA08_RS09570	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA08_RS09575	COG1469	GTP cyclohydrolase I activity
EBA08_RS09585	COG0617	tRNA 3'-terminal CCA addition
EBA08_RS09605	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EBA08_RS09635	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA08_RS09655	COG4251	negative regulation of phosphorylation
EBA08_RS09655	COG3706	GGDEF domain
EBA08_RS09655	COG5001	Diguanylate cyclase
EBA08_RS09655	COG2203	Gaf domain
EBA08_RS09665	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA08_RS09675	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EBA08_RS09690	COG0671	phosphoesterase, PA-phosphatase related
EBA08_RS09710	COG1794	racemase activity, acting on amino acids and derivatives
EBA08_RS09720	COG0697	spore germination
EBA08_RS09725	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EBA08_RS09750	COG1012	belongs to the aldehyde dehydrogenase family
EBA08_RS09815	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EBA08_RS09830	COG0124	histidyl-tRNA synthetase
EBA08_RS09850	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EBA08_RS09865	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EBA08_RS09865	COG0131	Imidazoleglycerol-phosphate dehydratase
EBA08_RS09875	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EBA08_RS09885	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EBA08_RS09885	COG0140	phosphoribosyl-ATP diphosphatase activity
EBA08_RS09905	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EBA08_RS09910	COG0235	Class ii aldolase
EBA08_RS09915	COG0531	amino acid
EBA08_RS09920	COG0531	amino acid
EBA08_RS09930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EBA08_RS09935	COG0277	FAD linked oxidase domain protein
EBA08_RS09960	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EBA08_RS10015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBA08_RS10020	COG2258	MOSC domain
EBA08_RS10025	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EBA08_RS10030	COG0505	Belongs to the CarA family
EBA08_RS10040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EBA08_RS10045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA08_RS10055	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EBA08_RS10070	COG3279	Response regulator of the LytR AlgR family
EBA08_RS10095	COG2205	protein histidine kinase activity
EBA08_RS10095	COG2198	Histidine kinase
EBA08_RS10095	COG0784	Response regulator, receiver
EBA08_RS10100	COG1024	Enoyl-CoA hydratase
EBA08_RS10105	COG0318	PFAM AMP-dependent synthetase and ligase
EBA08_RS10135	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA08_RS10165	COG0840	transmembrane signaling receptor activity
EBA08_RS10175	COG0835	chemotaxis
EBA08_RS10190	COG0840	transmembrane signaling receptor activity
EBA08_RS10195	COG0840	transmembrane signaling receptor activity
EBA08_RS10200	COG0840	transmembrane signaling receptor activity
EBA08_RS10215	COG0840	transmembrane signaling receptor activity
EBA08_RS10225	COG0840	transmembrane signaling receptor activity
EBA08_RS10230	COG0840	transmembrane signaling receptor activity
EBA08_RS10260	COG0840	transmembrane signaling receptor activity
EBA08_RS10265	COG2826	transposase and inactivated derivatives, IS30 family
EBA08_RS10285	COG0745	RESPONSE REGULATOR receiver
EBA08_RS10295	COG0835	chemotaxis
EBA08_RS10300	COG1192	Involved in chromosome partitioning
EBA08_RS10305	COG1360	Flagellar Motor Protein
EBA08_RS10310	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EBA08_RS10330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA08_RS10370	COG3039	Transposase
EBA08_RS10435	COG0643	Histidine kinase
EBA08_RS10435	COG0784	Response regulator, receiver
EBA08_RS10435	COG2198	Histidine kinase
EBA08_RS10490	COG1684	flagellar biosynthetic protein fliR
EBA08_RS10505	COG3190	flagellar
EBA08_RS10555	COG1677	Flagellar hook-basal body complex protein FliE
EBA08_RS10590	COG1028	Short-chain dehydrogenase reductase Sdr
EBA08_RS10600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA08_RS10620	COG2201	protein-glutamate methylesterase activity
EBA08_RS10650	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EBA08_RS10655	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EBA08_RS10670	COG1705	Flagellar rod assembly protein muramidase FlgJ
EBA08_RS10670	COG3951	Flagellar rod assembly protein muramidase FlgJ
EBA08_RS10675	COG1706	bacterial-type flagellum-dependent cell motility
EBA08_RS10680	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EBA08_RS10695	COG4787	bacterial-type flagellum-dependent cell motility
EBA08_RS10705	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EBA08_RS10710	COG1558	bacterial-type flagellum-dependent cell motility
EBA08_RS10720	COG0784	Response regulator, receiver
EBA08_RS10720	COG0835	chemotaxis
EBA08_RS10740	COG5002	protein histidine kinase activity
EBA08_RS10750	COG4585	Histidine kinase
EBA08_RS10785	COG0482	sulfurtransferase activity
EBA08_RS10800	COG0542	response to heat
EBA08_RS10825	COG0492	ferredoxin-NADP+ reductase activity
EBA08_RS10830	COG1674	ftsk spoiiie
EBA08_RS10855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EBA08_RS10875	COG0038	chloride channel
EBA08_RS10880	COG0183	Belongs to the thiolase family
EBA08_RS10885	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA08_RS10885	COG1024	Enoyl-CoA hydratase
EBA08_RS10900	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EBA08_RS10920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA08_RS10925	COG1160	GTP binding
EBA08_RS10930	COG0303	'Molybdopterin
EBA08_RS10940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EBA08_RS10950	COG2826	transposase and inactivated derivatives, IS30 family
EBA08_RS10975	COG0746	molybdenum cofactor guanylyltransferase activity
EBA08_RS11000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EBA08_RS11000	COG1648	precorrin-2 dehydrogenase activity
EBA08_RS11040	COG3039	Transposase
EBA08_RS11065	COG5001	Diguanylate cyclase
EBA08_RS11085	COG4566	intracellular signal transduction
EBA08_RS11210	COG1024	Enoyl-CoA hydratase
EBA08_RS11215	COG1024	Enoyl-CoA hydratase
EBA08_RS11225	COG1024	Enoyl-CoA hydratase
EBA08_RS11240	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EBA08_RS11350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA08_RS11355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA08_RS11405	COG1858	cytochrome C peroxidase
EBA08_RS11435	COG0515	serine threonine protein kinase
EBA08_RS11440	COG0631	protein serine/threonine phosphatase activity
EBA08_RS11500	COG2826	transposase and inactivated derivatives, IS30 family
EBA08_RS11515	COG3039	Transposase
EBA08_RS11600	COG3039	Transposase
EBA08_RS11615	COG2154	pterin-4-alpha-carbinolamine dehydratase
EBA08_RS11630	COG3064	Membrane
EBA08_RS11640	COG1530	ribonuclease E activity
EBA08_RS11655	COG1054	Belongs to the UPF0176 family
EBA08_RS11675	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EBA08_RS11715	COG0322	excinuclease ABC activity
EBA08_RS11725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBA08_RS11735	COG1663	tetraacyldisaccharide 4'-kinase activity
EBA08_RS11750	COG0811	peptide transport
EBA08_RS11775	COG4591	ABC-type transport system involved in lipoprotein release permease component
EBA08_RS11790	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EBA08_RS11805	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EBA08_RS11820	COG0354	folic acid binding
EBA08_RS11835	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA08_RS11845	COG0363	glucosamine-6-phosphate deaminase activity
EBA08_RS11850	COG0129	dihydroxy-acid dehydratase activity
EBA08_RS11855	COG0800	Aldolase
EBA08_RS11940	COG2205	protein histidine kinase activity
EBA08_RS11940	COG0784	Response regulator, receiver
EBA08_RS11955	COG2183	response to ionizing radiation
EBA08_RS11965	COG0723	plastoquinol--plastocyanin reductase activity
EBA08_RS11965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA08_RS11980	COG3243	poly(R)-hydroxyalkanoic acid synthase
EBA08_RS11990	COG1183	phosphatidylcholine synthase activity
EBA08_RS11995	COG1028	Short-chain dehydrogenase reductase Sdr
EBA08_RS12010	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EBA08_RS12020	COG0668	transmembrane transport
EBA08_RS12040	COG1914	H( )-stimulated, divalent metal cation uptake system
EBA08_RS12070	COG0583	DNA-binding transcription factor activity
EBA08_RS12095	COG0583	DNA-binding transcription factor activity
EBA08_RS12100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA08_RS12105	COG3002	Belongs to the UPF0753 family
EBA08_RS12110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA08_RS12110	COG0519	Catalyzes the synthesis of GMP from XMP
EBA08_RS12120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EBA08_RS12135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EBA08_RS12145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA08_RS12150	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EBA08_RS12160	COG0776	regulation of translation
EBA08_RS12165	COG0539	negative regulation of cytoplasmic translation
EBA08_RS12170	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EBA08_RS12185	COG2957	Belongs to the agmatine deiminase family
EBA08_RS12195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA08_RS12220	COG0395	ABC-type sugar transport system, permease component
EBA08_RS12225	COG1175	transmembrane transport
EBA08_RS12255	COG2350	Protein conserved in bacteria
EBA08_RS12260	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EBA08_RS12265	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EBA08_RS12270	COG1187	pseudouridine synthase activity
EBA08_RS12290	COG0436	Aminotransferase
EBA08_RS12295	COG4133	protoheme IX ABC transporter activity
EBA08_RS12345	COG1278	Cold shock
EBA08_RS12355	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EBA08_RS12360	COG4988	ABC transporter
EBA08_RS12370	COG1271	oxidase subunit
EBA08_RS12425	COG0165	Argininosuccinate lyase
EBA08_RS12440	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EBA08_RS12445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA08_RS12450	COG0137	argininosuccinate synthase activity
EBA08_RS12455	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EBA08_RS12470	COG2166	iron-sulfur cluster assembly
EBA08_RS12495	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EBA08_RS12510	COG4302	ethanolamine ammonia-lyase activity
EBA08_RS12525	COG4677	pectinesterase activity
EBA08_RS12550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EBA08_RS12555	COG0402	S-adenosylhomocysteine deaminase activity
EBA08_RS12575	COG1509	lysine 2,3-aminomutase activity
EBA08_RS12580	COG5001	Diguanylate cyclase
EBA08_RS12580	COG3300	MHYT domain
EBA08_RS12595	COG0483	inositol monophosphate 1-phosphatase activity
EBA08_RS12600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA08_RS12625	COG0488	(ABC) transporter
EBA08_RS12630	COG0513	Belongs to the DEAD box helicase family
EBA08_RS12640	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EBA08_RS12650	COG0625	glutathione transferase activity
EBA08_RS12660	COG1671	Belongs to the UPF0178 family
EBA08_RS12665	COG4681	YaeQ
EBA08_RS12670	COG2081	HI0933 family
EBA08_RS12675	COG1716	ATPase activity
EBA08_RS12675	COG5001	Diguanylate cyclase
EBA08_RS12680	COG0501	Belongs to the peptidase M48B family
EBA08_RS12690	COG1028	Short-chain dehydrogenase reductase Sdr
EBA08_RS12710	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EBA08_RS12715	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA08_RS12720	COG0802	atpase or kinase
EBA08_RS12725	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EBA08_RS12725	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EBA08_RS12730	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA08_RS12750	COG3039	Transposase
EBA08_RS12760	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA08_RS12805	COG0835	chemotaxis
EBA08_RS12810	COG0840	transmembrane signaling receptor activity
EBA08_RS12840	COG2969	positive regulation of protein catabolic process
EBA08_RS12845	COG0625	glutathione transferase activity
EBA08_RS12850	COG2857	Cytochrome c1
EBA08_RS12855	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EBA08_RS12860	COG0723	plastoquinol--plastocyanin reductase activity
EBA08_RS12870	COG0741	lytic transglycosylase activity
EBA08_RS12900	COG1702	phosphate starvation-inducible protein PhoH
EBA08_RS12920	COG4535	Mg2 and Co2 transporter CorC
EBA08_RS12935	COG1012	belongs to the aldehyde dehydrogenase family
EBA08_RS12940	COG1177	transmembrane transport
EBA08_RS12945	COG1176	ABC-type spermidine putrescine transport system, permease component I
EBA08_RS12955	COG3842	ATPase activity
EBA08_RS12985	COG3039	Transposase
EBA08_RS13010	COG0174	glutamine synthetase
EBA08_RS13015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA08_RS13025	COG0477	Major facilitator Superfamily
EBA08_RS13035	COG0243	molybdopterin cofactor binding
EBA08_RS13045	COG2223	nitrite transmembrane transporter activity
EBA08_RS13055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EBA08_RS13060	COG1121	(ABC) transporter
EBA08_RS13070	COG2733	membrane
EBA08_RS13075	COG2205	protein histidine kinase activity
EBA08_RS13075	COG5002	protein histidine kinase activity
EBA08_RS13075	COG0784	Response regulator, receiver
EBA08_RS13085	COG3039	Transposase
EBA08_RS13095	COG0477	Major facilitator Superfamily
EBA08_RS13135	COG3039	Transposase
EBA08_RS13145	COG2902	Dehydrogenase
EBA08_RS13155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA08_RS13160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA08_RS13175	COG1609	Transcriptional regulator
EBA08_RS13180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA08_RS13180	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA08_RS13185	COG1105	Belongs to the carbohydrate kinase PfkB family
EBA08_RS13190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA08_RS13190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA08_RS13240	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBA08_RS13250	COG1862	Preprotein translocase
EBA08_RS13255	COG0343	queuine tRNA-ribosyltransferase activity
EBA08_RS13320	COG0405	Gamma-glutamyltransferase
EBA08_RS13325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EBA08_RS13340	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EBA08_RS13345	COG0742	ribosomal rna small subunit methyltransferase
EBA08_RS13350	COG0326	Molecular chaperone. Has ATPase activity
EBA08_RS13395	COG4206	TonB-dependent receptor
EBA08_RS13450	COG3039	Transposase
EBA08_RS13455	COG3039	Transposase
EBA08_RS13465	COG0531	amino acid
EBA08_RS13480	COG0006	proline dipeptidase activity
EBA08_RS13490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA08_RS13505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA08_RS13510	COG3938	Belongs to the proline racemase family
EBA08_RS13520	COG0552	protein localization to endoplasmic reticulum
EBA08_RS13535	COG1194	a g-specific adenine glycosylase
EBA08_RS13545	COG4191	Histidine kinase
EBA08_RS13545	COG0784	Response regulator, receiver
EBA08_RS13550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EBA08_RS13575	COG3040	lipid binding
EBA08_RS13585	COG1960	acyl-CoA dehydrogenase activity
EBA08_RS13595	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EBA08_RS13625	COG0438	transferase activity, transferring glycosyl groups
EBA08_RS13635	COG0438	transferase activity, transferring glycosyl groups
EBA08_RS13640	COG0438	transferase activity, transferring glycosyl groups
EBA08_RS13695	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EBA08_RS13710	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EBA08_RS13735	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EBA08_RS13750	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EBA08_RS13755	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EBA08_RS13760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EBA08_RS13765	COG3115	cell septum assembly
EBA08_RS13785	COG0360	Binds together with S18 to 16S ribosomal RNA
EBA08_RS13790	COG0316	Belongs to the HesB IscA family
EBA08_RS13825	COG0288	reversible hydration of carbon dioxide
EBA08_RS13850	COG3844	kynureninase activity
EBA08_RS13860	COG2925	Exonuclease
EBA08_RS13870	COG0667	Aldo Keto reductase
EBA08_RS13900	COG0116	Belongs to the methyltransferase superfamily
EBA08_RS13900	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBA08_RS13945	COG0494	nUDIX hydrolase
EBA08_RS13955	COG1024	Enoyl-CoA hydratase
EBA08_RS13965	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EBA08_RS13970	COG0659	secondary active sulfate transmembrane transporter activity
EBA08_RS13995	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EBA08_RS14000	COG0573	inorganic phosphate transmembrane transporter activity
EBA08_RS14015	COG0704	Plays a role in the regulation of phosphate uptake
EBA08_RS14025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA08_RS14035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA08_RS14050	COG0557	exoribonuclease II activity
EBA08_RS14080	COG1960	acyl-CoA dehydrogenase activity
EBA08_RS14085	COG2226	methyltransferase
EBA08_RS14090	COG0646	methionine synthase
EBA08_RS14090	COG1410	methionine synthase
EBA08_RS14095	COG0646	methionine synthase
EBA08_RS14095	COG1410	methionine synthase
EBA08_RS14105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA08_RS14115	COG1609	Transcriptional regulator
EBA08_RS14130	COG2900	Belongs to the SlyX family
EBA08_RS14145	COG0386	Belongs to the glutathione peroxidase family
EBA08_RS14155	COG1725	Transcriptional regulator
EBA08_RS14160	COG1131	(ABC) transporter
EBA08_RS14200	COG3039	Transposase
EBA08_RS14230	COG2850	peptidyl-arginine hydroxylation
EBA08_RS14265	COG1132	(ABC) transporter
EBA08_RS14295	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EBA08_RS14305	COG0484	heat shock protein binding
EBA08_RS14310	COG0443	Heat shock 70 kDa protein
EBA08_RS14315	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EBA08_RS14325	COG0497	DNA recombination
EBA08_RS14335	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA08_RS14345	COG2914	Belongs to the UPF0125 (RnfH) family
EBA08_RS14355	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EBA08_RS14380	COG3039	Transposase
EBA08_RS14425	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EBA08_RS14440	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EBA08_RS14450	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EBA08_RS14455	COG0174	glutamine synthetase
EBA08_RS14520	COG0415	Belongs to the DNA photolyase family
EBA08_RS14525	COG0305	Participates in initiation and elongation during chromosome replication
EBA08_RS14535	COG0367	asparagine synthase
EBA08_RS14565	COG0084	hydrolase, TatD family'
EBA08_RS14570	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EBA08_RS14610	COG0840	transmembrane signaling receptor activity
EBA08_RS14625	COG3039	Transposase
EBA08_RS14640	COG3039	Transposase
EBA08_RS14670	COG0386	Belongs to the glutathione peroxidase family
EBA08_RS14770	COG2814	Major facilitator Superfamily
EBA08_RS14775	COG1566	PFAM secretion protein HlyD family protein
EBA08_RS14790	COG2207	Transcriptional regulator
EBA08_RS14820	COG4774	siderophore transport
EBA08_RS14830	COG0367	asparagine synthase
EBA08_RS14835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA08_RS14845	COG1393	Belongs to the ArsC family
EBA08_RS14905	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EBA08_RS14920	COG0233	cytoplasmic translational termination
EBA08_RS14930	COG0575	Belongs to the CDS family
EBA08_RS14935	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EBA08_RS14940	COG0750	zinc metalloprotease
EBA08_RS14960	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBA08_RS14965	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBA08_RS14985	COG0825	malonyl-CoA metabolic process
EBA08_RS15010	COG1981	membrane
EBA08_RS15060	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA08_RS15075	COG2040	homocysteine
EBA08_RS15080	COG0833	amino acid
EBA08_RS15085	COG0346	lactoylglutathione lyase activity
EBA08_RS15095	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBA08_RS15095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBA08_RS15105	COG2878	Part of a membrane complex involved in electron transport
EBA08_RS15125	COG1595	DNA-templated transcription, initiation
EBA08_RS15150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA08_RS15165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA08_RS15170	COG0251	oxidation-reduction process
EBA08_RS15180	COG0392	lysyltransferase activity
EBA08_RS15180	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EBA08_RS15220	COG2814	Major facilitator Superfamily
EBA08_RS15225	COG1902	pentaerythritol trinitrate reductase activity
EBA08_RS15240	COG2824	Alkylphosphonate utilization operon protein PhnA
EBA08_RS15250	COG1047	Peptidyl-prolyl cis-trans
EBA08_RS15290	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EBA08_RS15305	COG1451	nucleotide metabolic process
EBA08_RS15325	COG0183	Belongs to the thiolase family
EBA08_RS15355	COG1793	dna ligase
EBA08_RS15355	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EBA08_RS15365	COG1793	dna ligase
EBA08_RS15370	COG1201	RNA secondary structure unwinding
EBA08_RS15390	COG1278	Cold shock
EBA08_RS15395	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EBA08_RS15410	COG3046	protein related to deoxyribodipyrimidine photolyase
EBA08_RS15415	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EBA08_RS15425	COG2954	triphosphatase activity
EBA08_RS15440	COG1381	Involved in DNA repair and RecF pathway recombination
EBA08_RS15470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA08_RS15485	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA08_RS15485	COG1024	Enoyl-CoA hydratase
EBA08_RS15505	COG1024	Enoyl-CoA hydratase
EBA08_RS15510	COG1960	acyl-CoA dehydrogenase activity
EBA08_RS15585	COG2353	YceI-like domain
EBA08_RS15610	COG1760	l-serine dehydratase
EBA08_RS15620	COG0626	cystathionine gamma-synthase activity
EBA08_RS15625	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA08_RS15630	COG0739	heme binding
EBA08_RS15640	COG1272	protein, Hemolysin III
EBA08_RS15660	COG0516	GMP reductase activity
EBA08_RS15660	COG0517	IMP dehydrogenase activity
EBA08_RS15665	COG0463	Glycosyl transferase, family 2
EBA08_RS15675	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EBA08_RS15685	COG4771	TonB-dependent receptor
EBA08_RS15690	COG1309	transcriptional regulator
EBA08_RS15700	COG1960	acyl-CoA dehydrogenase activity
EBA08_RS15730	COG0509	glycine decarboxylation via glycine cleavage system
EBA08_RS15745	COG0330	HflC and HflK could
EBA08_RS15755	COG1742	UPF0060 membrane protein
EBA08_RS15760	COG3956	TIGRFAM MazG family protein
EBA08_RS15770	COG0494	nUDIX hydrolase
EBA08_RS15780	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EBA08_RS15785	COG0837	glucose binding
EBA08_RS15800	COG1388	LysM domain
EBA08_RS15800	COG3858	chitin binding
EBA08_RS15820	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA08_RS15845	COG2801	Transposase and inactivated derivatives
EBA08_RS15855	COG2826	transposase and inactivated derivatives, IS30 family
EBA08_RS15870	COG3039	Transposase
EBA08_RS15930	COG3537	Alpha-1,2-mannosidase
EBA08_RS15975	COG3142	Participates in the control of copper homeostasis
EBA08_RS15980	COG1446	asparaginase
EBA08_RS15990	COG2304	oxidoreductase activity
EBA08_RS16015	COG2198	Histidine kinase
EBA08_RS16015	COG0784	Response regulator, receiver
EBA08_RS16015	COG0643	Histidine kinase
EBA08_RS16020	COG0840	transmembrane signaling receptor activity
EBA08_RS16025	COG0835	chemotaxis
EBA08_RS16040	COG0189	ligase activity
EBA08_RS16050	COG1397	ADP-ribosylglycohydrolase
EBA08_RS16060	COG1199	ATP-dependent helicase activity
EBA08_RS16070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EBA08_RS16075	COG1215	transferase activity, transferring glycosyl groups
EBA08_RS16085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA08_RS16135	COG1643	Atp-dependent helicase
EBA08_RS16140	COG0783	Belongs to the Dps family
EBA08_RS16150	COG0514	ATP-dependent DNA helicase (RecQ)
EBA08_RS16165	COG3039	Transposase
EBA08_RS16180	COG1187	pseudouridine synthase activity
EBA08_RS16220	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EBA08_RS16230	COG0602	queuosine metabolic process
EBA08_RS16240	COG2885	chlorophyll binding
EBA08_RS16245	COG0823	Involved in the tonB-independent uptake of proteins
EBA08_RS16255	COG0848	biopolymer transport protein
EBA08_RS16265	COG0824	Thioesterase
EBA08_RS16270	COG2255	four-way junction helicase activity
EBA08_RS16285	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EBA08_RS16310	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EBA08_RS16325	COG0477	Major facilitator Superfamily
EBA08_RS16360	COG0488	(ABC) transporter
EBA08_RS16390	COG4651	solute:proton antiporter activity
EBA08_RS16390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EBA08_RS16435	COG4772	TonB-dependent receptor
EBA08_RS16445	COG4264	IucA IucC family
EBA08_RS16450	COG2814	Major facilitator Superfamily
EBA08_RS16460	COG0019	diaminopimelate decarboxylase activity
EBA08_RS16515	COG4206	TonB-dependent receptor
EBA08_RS16550	COG0542	response to heat
EBA08_RS16575	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EBA08_RS16585	COG0534	Mate efflux family protein
EBA08_RS16600	COG0336	Belongs to the RNA methyltransferase TrmD family
EBA08_RS16605	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EBA08_RS16610	COG0228	four-way junction DNA binding
EBA08_RS16635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EBA08_RS16645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA08_RS16685	COG2172	sigma factor antagonist activity
EBA08_RS16690	COG1366	Belongs to the anti-sigma-factor antagonist family
EBA08_RS16695	COG1366	Belongs to the anti-sigma-factor antagonist family
EBA08_RS16705	COG0326	Molecular chaperone. Has ATPase activity
EBA08_RS16710	COG2207	Transcriptional regulator
EBA08_RS16765	COG3209	COG3209 Rhs family protein
EBA08_RS16780	COG3209	COG3209 Rhs family protein
EBA08_RS16800	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EBA08_RS16805	COG1845	cytochrome c oxidase, subunit III
EBA08_RS16810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EBA08_RS16825	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EBA08_RS16830	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EBA08_RS16845	COG0728	peptidoglycan biosynthetic process
EBA08_RS16850	COG0268	Binds directly to 16S ribosomal RNA
EBA08_RS16855	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EBA08_RS16860	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EBA08_RS16870	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EBA08_RS16875	COG0824	Thioesterase
EBA08_RS16890	COG1946	Acyl-CoA thioesterase
EBA08_RS16900	COG1595	DNA-templated transcription, initiation
EBA08_RS16915	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EBA08_RS16955	COG1877	trehalose-phosphatase activity
EBA08_RS16960	COG3387	PFAM Glycoside hydrolase 15-related
EBA08_RS16995	COG0564	pseudouridine synthase activity
EBA08_RS17000	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA08_RS17005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA08_RS17005	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EBA08_RS17020	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EBA08_RS17025	COG0045	succinate-CoA ligase (ADP-forming) activity
EBA08_RS17065	COG2194	sulfuric ester hydrolase activity
EBA08_RS17070	COG4969	Belongs to the N-Me-Phe pilin family
EBA08_RS17080	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EBA08_RS17085	COG0237	dephospho-CoA kinase activity
EBA08_RS17090	COG2205	protein histidine kinase activity
EBA08_RS17095	COG0745	RESPONSE REGULATOR receiver
EBA08_RS17115	COG3039	Transposase
EBA08_RS17140	COG3039	Transposase
EBA08_RS17155	COG2801	Transposase and inactivated derivatives
EBA08_RS17165	COG3039	Transposase
EBA08_RS17190	COG2022	thiamine diphosphate biosynthetic process
EBA08_RS17205	COG0471	metal ion transport
EBA08_RS17205	COG3273	potassium ion transport
EBA08_RS17235	COG1970	mechanosensitive ion channel activity
EBA08_RS17270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA08_RS17285	COG0308	aminopeptidase N
EBA08_RS17290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA08_RS17300	COG0529	Catalyzes the synthesis of activated sulfate
EBA08_RS17300	COG2895	sulfate adenylyltransferase (ATP) activity
EBA08_RS17305	COG0175	sulfate reduction
EBA08_RS17310	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA08_RS17315	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EBA08_RS17320	COG0175	sulfate reduction
EBA08_RS17340	COG2198	Histidine kinase
EBA08_RS17340	COG2205	protein histidine kinase activity
EBA08_RS17340	COG0784	Response regulator, receiver
EBA08_RS17380	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EBA08_RS17385	COG3588	fructose-bisphosphate aldolase
EBA08_RS17395	COG0469	pyruvate kinase activity
EBA08_RS17420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EBA08_RS17430	COG3453	Protein conserved in bacteria
EBA08_RS17430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA08_RS17435	COG0725	ABC transporter, periplasmic molybdate-binding protein
EBA08_RS17440	COG4149	molybdate abc transporter
EBA08_RS17445	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EBA08_RS17465	COG0642	Histidine kinase
EBA08_RS17480	COG1028	Short-chain dehydrogenase reductase Sdr
EBA08_RS17490	COG1022	Amp-dependent synthetase and ligase
EBA08_RS17515	COG1376	ErfK ybiS ycfS ynhG family protein
EBA08_RS17520	COG0739	heme binding
EBA08_RS17535	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EBA08_RS17540	COG1301	dicarboxylic acid transport
EBA08_RS17560	COG2304	oxidoreductase activity
EBA08_RS17580	COG0714	Associated with various cellular activities
EBA08_RS17615	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EBA08_RS17650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EBA08_RS17660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA08_RS17680	COG1561	YicC-like family, N-terminal region
EBA08_RS17685	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EBA08_RS17700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EBA08_RS17730	COG0006	proline dipeptidase activity
EBA08_RS17775	COG2912	Transglutaminase-like superfamily
EBA08_RS17780	COG1773	rubredoxin
EBA08_RS17785	COG0352	thiamine-phosphate diphosphorylase activity
EBA08_RS17795	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EBA08_RS17810	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EBA08_RS17855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EBA08_RS17880	COG0671	phosphoesterase, PA-phosphatase related
EBA08_RS17895	COG3781	membrane
EBA08_RS17905	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBA08_RS17920	COG3039	Transposase
EBA08_RS17935	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EBA08_RS17945	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EBA08_RS17970	COG3710	Transcriptional regulator
EBA08_RS17975	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EBA08_RS17985	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EBA08_RS18015	COG2226	methyltransferase
EBA08_RS18020	COG0066	3-isopropylmalate dehydratase activity
EBA08_RS18025	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EBA08_RS18045	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBA08_RS18050	COG1538	Outer membrane efflux protein
EBA08_RS18055	COG1519	Transferase
EBA08_RS18060	COG1560	Kdo2-lipid A biosynthetic process
EBA08_RS18080	COG3039	Transposase
EBA08_RS18090	COG2826	transposase and inactivated derivatives, IS30 family
EBA08_RS18160	COG3039	Transposase
EBA08_RS18175	COG0281	malic enzyme
EBA08_RS18175	COG0280	phosphate acetyltransferase
EBA08_RS18195	COG4191	Histidine kinase
EBA08_RS18210	COG0583	DNA-binding transcription factor activity
EBA08_RS18235	COG2197	response regulator
EBA08_RS18245	COG0642	Histidine kinase
EBA08_RS18265	COG2851	Citrate transporter
EBA08_RS18270	COG1028	Short-chain dehydrogenase reductase Sdr
EBA08_RS18280	COG1609	Transcriptional regulator
EBA08_RS18290	COG2211	Major facilitator Superfamily
EBA08_RS18320	COG0436	Aminotransferase
EBA08_RS18340	COG0726	polysaccharide deacetylase
EBA08_RS18345	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA08_RS18365	COG0402	S-adenosylhomocysteine deaminase activity
EBA08_RS18415	COG0242	peptide deformylase activity
EBA08_RS18420	COG3039	Transposase
EBA08_RS18455	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EBA08_RS18515	COG2188	Transcriptional regulator
EBA08_RS18530	COG1450	Type ii and iii secretion system protein
EBA08_RS18545	COG3166	PFAM Fimbrial assembly family protein
EBA08_RS18550	COG3156	type II secretion system protein K
EBA08_RS18555	COG4795	General secretion pathway protein
EBA08_RS18560	COG2165	general secretion pathway protein
EBA08_RS18565	COG4970	Tfp pilus assembly protein FimT
EBA08_RS18570	COG2165	general secretion pathway protein
EBA08_RS18575	COG1459	type II secretion system
EBA08_RS18585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA08_RS18590	COG1404	Belongs to the peptidase S8 family
EBA08_RS18595	COG5295	Hep Hag repeat protein
EBA08_RS18605	COG0047	phosphoribosylformylglycinamidine synthase activity
EBA08_RS18605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBA08_RS18615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EBA08_RS18620	COG4974	Belongs to the 'phage' integrase family
EBA08_RS18635	COG0795	lipopolysaccharide-transporting ATPase activity
EBA08_RS18645	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBA08_RS18670	COG0525	valine-tRNA ligase activity
EBA08_RS18700	COG2826	transposase and inactivated derivatives, IS30 family
EBA08_RS18710	COG2826	transposase and inactivated derivatives, IS30 family
EBA08_RS18735	COG1183	phosphatidylcholine synthase activity
EBA08_RS18745	COG0442	prolyl-tRNA aminoacylation
EBA08_RS18760	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA08_RS18765	COG1127	ABC transporter
EBA08_RS18770	COG3218	ABC-type transport auxiliary lipoprotein component
EBA08_RS18770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA08_RS18815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBA08_RS18820	COG0662	Cupin 2, conserved barrel domain protein
EBA08_RS18820	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EBA08_RS18850	COG2086	electron transfer activity
EBA08_RS18920	COG0626	cystathionine gamma-synthase activity
EBA08_RS18950	COG0625	glutathione transferase activity
EBA08_RS18965	COG0513	Belongs to the DEAD box helicase family
EBA08_RS18975	COG0720	synthase
EBA08_RS18985	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EBA08_RS18990	COG1956	GAF domain-containing protein
EBA08_RS19000	COG0546	phosphoglycolate phosphatase activity
EBA08_RS19030	COG0339	signal peptide processing
EBA08_RS19080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA08_RS19145	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EBA08_RS19150	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EBA08_RS19155	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EBA08_RS19165	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EBA08_RS19175	COG0356	it plays a direct role in the translocation of protons across the membrane
EBA08_RS19195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EBA08_RS19205	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBA08_RS19240	COG2011	ABC-type metal ion transport system permease component
EBA08_RS19250	COG0697	spore germination
EBA08_RS19285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EBA08_RS19290	COG1187	pseudouridine synthase activity
EBA08_RS19295	COG2813	Specifically methylates the guanine in position
EBA08_RS19325	COG2202	Pas domain
EBA08_RS19325	COG2205	protein histidine kinase activity
EBA08_RS19350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA08_RS19400	COG0745	RESPONSE REGULATOR receiver
EBA08_RS19415	COG1404	Belongs to the peptidase S8 family
EBA08_RS19430	COG0842	Transport permease protein
EBA08_RS19435	COG1131	(ABC) transporter
EBA08_RS19440	COG0025	NhaP-type Na H and K H
EBA08_RS19450	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EBA08_RS19460	COG1573	uracil-dna glycosylase
EBA08_RS19470	COG3384	dioxygenase
EBA08_RS19495	COG3590	peptidase
EBA08_RS19515	COG0531	amino acid
EBA08_RS19540	COG3685	Protein conserved in bacteria
EBA08_RS19545	COG3546	catalase activity
EBA08_RS19570	COG3039	Transposase
EBA08_RS19600	COG1271	oxidase subunit
EBA08_RS19605	COG1294	oxidase, subunit
EBA08_RS19635	COG1063	alcohol dehydrogenase
EBA08_RS19730	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EBA08_RS19730	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EBA08_RS19740	COG1473	amidohydrolase
EBA08_RS19745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA08_RS19750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA08_RS19775	COG5383	Protein conserved in bacteria
EBA08_RS19830	COG3023	N-Acetylmuramoyl-L-alanine amidase
EBA08_RS19840	COG4948	Mandelate Racemase Muconate Lactonizing
EBA08_RS19870	COG0531	amino acid
EBA08_RS19890	COG4682	membrane
EBA08_RS19895	COG2133	pyrroloquinoline quinone binding
EBA08_RS19915	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EBA08_RS19920	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EBA08_RS19930	COG1610	YqeY-like protein
EBA08_RS19950	COG1295	ribonuclease BN
EBA08_RS19955	COG0358	DNA primase activity
EBA08_RS20030	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EBA08_RS20045	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EBA08_RS20110	COG0739	heme binding
EBA08_RS20125	COG2211	Major facilitator Superfamily
EBA08_RS20130	COG0708	Exodeoxyribonuclease III
EBA08_RS20145	COG1192	Involved in chromosome partitioning
EBA08_RS20150	COG1475	DNA binding
EBA08_RS20170	COG0463	Glycosyl transferase, family 2
EBA08_RS20195	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EBA08_RS20220	COG4221	oxidoreductase activity
EBA08_RS20260	COG1166	arginine decarboxylase activity
EBA08_RS20265	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EBA08_RS20310	COG0606	chelatase, subunit chli
EBA08_RS20335	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EBA08_RS20355	COG3039	Transposase
EBA08_RS20415	COG1090	epimerase
EBA08_RS20425	COG0642	Histidine kinase
EBA08_RS20440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA08_RS20475	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBA08_RS20485	COG1595	DNA-templated transcription, initiation
EBA08_RS20490	COG0753	catalase activity
EBA08_RS20515	COG0697	spore germination
EBA08_RS20540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA08_RS20545	COG0180	Tryptophanyl-tRNA synthetase
EBA08_RS20550	COG3237	CsbD-like
EBA08_RS20565	COG0010	Belongs to the arginase family
EBA08_RS20585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EBA08_RS20600	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EBA08_RS20605	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EBA08_RS20605	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EBA08_RS20615	COG3228	Belongs to the MtfA family
EBA08_RS20645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA08_RS20700	COG3039	Transposase
EBA08_RS20705	COG1566	PFAM secretion protein HlyD family protein
EBA08_RS20720	COG1199	ATP-dependent helicase activity
EBA08_RS20765	COG0583	DNA-binding transcription factor activity
EBA08_RS20815	COG0625	glutathione transferase activity
EBA08_RS20825	COG2826	transposase and inactivated derivatives, IS30 family
EBA08_RS20855	COG4555	ABC transporter
EBA08_RS20865	COG1476	TRANSCRIPTIONal
EBA08_RS20885	COG1230	cation diffusion facilitator family transporter
EBA08_RS20890	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA08_RS20895	COG1131	(ABC) transporter
EBA08_RS20900	COG0842	Transport permease protein
EBA08_RS20910	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EBA08_RS20945	COG2951	lytic endotransglycosylase activity
EBA08_RS20960	COG1196	nuclear chromosome segregation
EBA08_RS20965	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA08_RS20975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA08_RS20990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EBA08_RS20990	COG1042	CoA-binding domain protein
EBA08_RS20990	COG0045	succinate-CoA ligase (ADP-forming) activity
EBA08_RS21000	COG2239	Acts as a magnesium transporter
EBA08_RS21025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA08_RS21030	COG3387	PFAM Glycoside hydrolase 15-related
EBA08_RS21045	COG3100	YcgL domain-containing protein
EBA08_RS21050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EBA08_RS21060	COG0463	Glycosyl transferase, family 2
EBA08_RS21070	COG1028	Short-chain dehydrogenase reductase Sdr
EBA08_RS21100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBA08_RS21115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBA08_RS21165	COG0408	coproporphyrinogen oxidase activity
EBA08_RS21245	COG0210	DNA helicase
EBA08_RS21265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA08_RS21280	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EBA08_RS21295	COG2159	amidohydrolase
EBA08_RS21325	COG0357	Ribosomal RNA small subunit methyltransferase G
EBA08_RS21330	COG3540	Alkaline phosphatase
EBA08_RS21340	COG2091	lysine biosynthetic process via aminoadipic acid
EBA08_RS21355	COG0708	Exodeoxyribonuclease III
EBA08_RS21370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EBA08_RS21375	COG3162	membrane
EBA08_RS21430	COG1028	Short-chain dehydrogenase reductase Sdr
EBA08_RS21435	COG0179	Fumarylacetoacetate (FAA) hydrolase
EBA08_RS21445	COG4948	Mandelate Racemase Muconate Lactonizing
EBA08_RS21450	COG3254	rhamnose metabolic process
EBA08_RS21455	COG0738	Major facilitator superfamily
EBA08_RS21460	COG1414	Transcriptional regulator
EBA08_RS21470	COG2205	protein histidine kinase activity
EBA08_RS21480	COG3459	Glycosyltransferase 36 associated
EBA08_RS21485	COG2211	Major facilitator Superfamily
EBA08_RS21490	COG3265	gluconokinase activity
EBA08_RS21495	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA08_RS21525	COG3039	Transposase
EBA08_RS21535	COG3039	Transposase
EBA08_RS21540	COG2911	Protein conserved in bacteria
EBA08_RS21545	COG0729	surface antigen
EBA08_RS21550	COG4771	TonB-dependent receptor
EBA08_RS21555	COG0457	Tetratricopeptide repeat
EBA08_RS21570	COG0752	glycyl-tRNA synthetase alpha subunit
EBA08_RS21575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA08_RS21585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA08_RS21585	COG0519	Catalyzes the synthesis of GMP from XMP
EBA08_RS21595	COG0805	protein transport
EBA08_RS21600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA08_RS21605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA08_RS21615	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EBA08_RS21645	COG2974	May be involved in recombination
EBA08_RS21650	COG0037	tRNA processing
EBA08_RS21675	COG3661	Belongs to the glycosyl hydrolase 67 family
EBA08_RS21685	COG4948	Mandelate Racemase Muconate Lactonizing
EBA08_RS21695	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA08_RS21700	COG0246	Mannitol dehydrogenase
EBA08_RS21735	COG2826	transposase and inactivated derivatives, IS30 family
EBA08_RS21760	COG3693	PFAM glycoside hydrolase, family 10
EBA08_RS21785	COG2211	Major facilitator Superfamily
EBA08_RS21800	COG3039	Transposase
EBA08_RS21830	COG2937	Belongs to the GPAT DAPAT family
EBA08_RS21865	COG0284	orotidine-5'-phosphate decarboxylase activity
EBA08_RS21870	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EBA08_RS21875	COG3132	Protein of unknown function, DUF480
EBA08_RS21890	COG0210	DNA helicase
EBA08_RS21905	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EBA08_RS21915	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EBA08_RS21970	COG0676	glucose-6-phosphate 1-epimerase activity
EBA08_RS21985	COG0730	response to heat
EBA08_RS22020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EBA08_RS22025	COG0302	gtp cyclohydrolase
EBA08_RS22055	COG2826	transposase and inactivated derivatives, IS30 family
EBA08_RS22065	COG0477	Major facilitator Superfamily
EBA08_RS22080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA08_RS22125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA08_RS22175	COG3237	CsbD-like
EBA08_RS22200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA08_RS22230	COG1304	FMN binding
EBA08_RS22255	COG4772	TonB-dependent receptor
EBA08_RS22265	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EBA08_RS22295	COG3039	Transposase
EBA08_RS22350	COG0564	pseudouridine synthase activity
EBA08_RS22365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA08_RS22380	COG3039	Transposase
EBA08_RS22400	COG3039	Transposase
EBA08_RS22425	COG3039	Transposase
EBA08_RS22505	COG1074	ATP-dependent DNA helicase activity
EBA08_RS22510	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EBA08_RS22515	COG1116	anion transmembrane transporter activity
EBA08_RS22525	COG3039	Transposase
EBA08_RS22530	COG3039	Transposase
EBA08_RS22545	COG1136	(ABC) transporter
EBA08_RS22565	COG1127	ABC transporter
EBA08_RS22570	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA08_RS22575	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA08_RS22590	COG2853	Lipoprotein
EBA08_RS22610	COG0386	Belongs to the glutathione peroxidase family
EBA08_RS22620	COG1322	Protein conserved in bacteria
EBA08_RS22625	COG3039	Transposase
EBA08_RS22650	COG1929	Belongs to the glycerate kinase type-1 family
EBA08_RS22655	COG2271	Major facilitator Superfamily
EBA08_RS22670	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBA08_RS22680	COG0861	Integral membrane protein TerC family
EBA08_RS22690	COG0584	glycerophosphoryl diester phosphodiesterase
EBA08_RS22700	COG0671	phosphoesterase, PA-phosphatase related
EBA08_RS22705	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EBA08_RS22710	COG0726	polysaccharide deacetylase