locus-tag	class	description
EBA12_RS00025	COG0187	DNA topoisomerase II activity
EBA12_RS00035	COG0501	Belongs to the peptidase M48B family
EBA12_RS00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EBA12_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA12_RS00095	COG3039	Transposase
EBA12_RS00145	COG0793	Belongs to the peptidase S41A family
EBA12_RS00150	COG4942	peptidase
EBA12_RS00160	COG2234	aminopeptidase activity
EBA12_RS00170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA12_RS00185	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA12_RS00195	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA12_RS00205	COG1064	alcohol dehydrogenase
EBA12_RS00235	COG0493	'glutamate synthase
EBA12_RS00240	COG0067	glutamate synthase
EBA12_RS00240	COG0069	glutamate synthase activity
EBA12_RS00240	COG0070	glutamate synthase
EBA12_RS00310	COG1111	helicase
EBA12_RS00310	COG1205	dead DEAH box helicase
EBA12_RS00315	COG1272	protein, Hemolysin III
EBA12_RS00345	COG2032	superoxide dismutase activity
EBA12_RS00350	COG2204	response regulator
EBA12_RS00355	COG3852	Histidine kinase
EBA12_RS00360	COG0004	ammonium transporteR
EBA12_RS00365	COG0347	Belongs to the P(II) protein family
EBA12_RS00370	COG0174	glutamine synthetase
EBA12_RS00375	COG1968	undecaprenyl-diphosphatase activity
EBA12_RS00425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA12_RS00435	COG2062	phosphohistidine phosphatase, SixA
EBA12_RS00440	COG0489	protein tyrosine kinase activity
EBA12_RS00460	COG1396	sequence-specific DNA binding
EBA12_RS00465	COG3550	peptidyl-serine autophosphorylation
EBA12_RS00470	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EBA12_RS00475	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA12_RS00490	COG1125	glycine betaine transport
EBA12_RS00505	COG1119	ATPase activity
EBA12_RS00520	COG1752	Esterase of the alpha-beta hydrolase superfamily
EBA12_RS00530	COG1522	sequence-specific DNA binding
EBA12_RS00535	COG3186	Phenylalanine-4-hydroxylase
EBA12_RS00565	COG1609	Transcriptional regulator
EBA12_RS00605	COG0366	Alpha amylase catalytic
EBA12_RS00610	COG0366	Alpha amylase catalytic
EBA12_RS00620	COG3039	Transposase
EBA12_RS00670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EBA12_RS00675	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EBA12_RS00690	COG0028	Belongs to the TPP enzyme family
EBA12_RS00695	COG4191	Histidine kinase
EBA12_RS00720	COG3039	Transposase
EBA12_RS00730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EBA12_RS00745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA12_RS00750	COG3177	Filamentation induced by cAMP protein fic
EBA12_RS00755	COG0596	Alpha beta hydrolase
EBA12_RS00765	COG0727	PFAM Uncharacterised protein family (UPF0153)
EBA12_RS00770	COG0318	PFAM AMP-dependent synthetase and ligase
EBA12_RS00775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EBA12_RS00790	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA12_RS00805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBA12_RS00820	COG0564	pseudouridine synthase activity
EBA12_RS00850	COG0339	signal peptide processing
EBA12_RS00895	COG4770	biotin carboxylase activity
EBA12_RS00900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EBA12_RS00905	COG1960	acyl-CoA dehydrogenase activity
EBA12_RS00960	COG0697	spore germination
EBA12_RS00970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EBA12_RS00975	COG1846	Transcriptional regulator
EBA12_RS00980	COG1764	response to oxidative stress
EBA12_RS01030	COG0656	L-ascorbic acid biosynthetic process
EBA12_RS01045	COG2130	NADP-dependent
EBA12_RS01060	COG1187	pseudouridine synthase activity
EBA12_RS01075	COG1643	Atp-dependent helicase
EBA12_RS01085	COG4807	Protein conserved in bacteria
EBA12_RS01090	COG2072	flavoprotein involved in K transport
EBA12_RS01110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EBA12_RS01115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA12_RS01155	COG3039	Transposase
EBA12_RS01200	COG0084	hydrolase, TatD family'
EBA12_RS01220	COG0583	DNA-binding transcription factor activity
EBA12_RS01225	COG2814	Major facilitator Superfamily
EBA12_RS01235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EBA12_RS01240	COG1902	pentaerythritol trinitrate reductase activity
EBA12_RS01270	COG0745	RESPONSE REGULATOR receiver
EBA12_RS01290	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA12_RS01295	COG0583	DNA-binding transcription factor activity
EBA12_RS01325	COG0702	epimerase
EBA12_RS01330	COG1733	regulation of RNA biosynthetic process
EBA12_RS01365	COG3039	Transposase
EBA12_RS01400	COG0129	dihydroxy-acid dehydratase activity
EBA12_RS01410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EBA12_RS01480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EBA12_RS01485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EBA12_RS01495	COG3485	protocatechuate 3,4-dioxygenase
EBA12_RS01500	COG3485	protocatechuate 3,4-dioxygenase
EBA12_RS01515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA12_RS01520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EBA12_RS01535	COG1414	Transcriptional regulator
EBA12_RS01575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EBA12_RS01615	COG0156	8-amino-7-oxononanoate synthase activity
EBA12_RS01620	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EBA12_RS01625	COG1040	competence protein
EBA12_RS01630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EBA12_RS01735	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EBA12_RS01810	COG1511	domain protein
EBA12_RS01810	COG3264	Mechanosensitive ion channel
EBA12_RS01820	COG3039	Transposase
EBA12_RS01825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBA12_RS01835	COG2354	Protein conserved in bacteria
EBA12_RS01860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EBA12_RS01885	COG0702	epimerase
EBA12_RS01895	COG1028	Short-chain dehydrogenase reductase Sdr
EBA12_RS01940	COG0513	Belongs to the DEAD box helicase family
EBA12_RS01950	COG3039	Transposase
EBA12_RS01980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EBA12_RS01990	COG3483	tryptophan 2,3-dioxygenase activity
EBA12_RS01995	COG3104	oligopeptide transport
EBA12_RS02015	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EBA12_RS02025	COG1320	monovalent cation:proton antiporter activity
EBA12_RS02030	COG2212	antiporter activity
EBA12_RS02040	COG0651	ATP synthesis coupled electron transport
EBA12_RS02045	COG1006	Multisubunit Na H antiporter MnhC subunit
EBA12_RS02050	COG2111	Na H antiporter
EBA12_RS02050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA12_RS02085	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EBA12_RS02095	COG0456	acetyltransferase
EBA12_RS02135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EBA12_RS02140	COG0134	indole-3-glycerol-phosphate synthase activity
EBA12_RS02150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EBA12_RS02155	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EBA12_RS02165	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EBA12_RS02170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EBA12_RS02175	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EBA12_RS02245	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EBA12_RS02265	COG2814	Major facilitator Superfamily
EBA12_RS02275	COG2814	Major facilitator Superfamily
EBA12_RS02280	COG1289	transmembrane transporter activity
EBA12_RS02290	COG0151	Belongs to the GarS family
EBA12_RS02300	COG0138	bifunctional purine biosynthesis protein purh
EBA12_RS02305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EBA12_RS02315	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EBA12_RS02370	COG0439	Biotin carboxylase
EBA12_RS02380	COG0511	ligase activity, forming carbon-carbon bonds
EBA12_RS02385	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EBA12_RS02400	COG1324	tolerance protein
EBA12_RS02420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EBA12_RS02440	COG0534	Mate efflux family protein
EBA12_RS02445	COG0616	signal peptide processing
EBA12_RS02455	COG1028	Short-chain dehydrogenase reductase Sdr
EBA12_RS02470	COG0009	L-threonylcarbamoyladenylate synthase
EBA12_RS02475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA12_RS02475	COG1754	DNA topoisomerase type I activity
EBA12_RS02495	COG0758	DNA mediated transformation
EBA12_RS02500	COG1652	LysM domain
EBA12_RS02505	COG0242	peptide deformylase activity
EBA12_RS02510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EBA12_RS02515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBA12_RS02515	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EBA12_RS02565	COG1560	Kdo2-lipid A biosynthetic process
EBA12_RS02575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA12_RS02605	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EBA12_RS02610	COG3118	belongs to the thioredoxin family
EBA12_RS02620	COG2884	Cell division ATP-binding protein ftsE
EBA12_RS02625	COG2177	Part of the ABC transporter FtsEX involved in
EBA12_RS02630	COG3437	response regulator, receiver
EBA12_RS02635	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EBA12_RS02640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA12_RS02645	COG2860	membrane
EBA12_RS02650	COG1252	NADH dehydrogenase
EBA12_RS02675	COG0459	protein refolding
EBA12_RS02690	COG3039	Transposase
EBA12_RS02700	COG3039	Transposase
EBA12_RS02710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EBA12_RS02725	COG3386	PFAM SMP-30 Gluconolaconase
EBA12_RS02740	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA12_RS02785	COG2353	YceI-like domain
EBA12_RS02905	COG4221	oxidoreductase activity
EBA12_RS02965	COG0697	spore germination
EBA12_RS02970	COG4305	rare lipoprotein A
EBA12_RS02975	COG5297	Belongs to the glycosyl hydrolase family 6
EBA12_RS02985	COG1113	amino acid transport
EBA12_RS02995	COG0598	Magnesium transport protein CorA
EBA12_RS03075	COG5001	Diguanylate cyclase
EBA12_RS03075	COG3300	MHYT domain
EBA12_RS03100	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA12_RS03100	COG5297	Belongs to the glycosyl hydrolase family 6
EBA12_RS03105	COG0659	secondary active sulfate transmembrane transporter activity
EBA12_RS03140	COG3275	phosphorelay sensor kinase activity
EBA12_RS03150	COG0181	hydroxymethylbilane synthase activity
EBA12_RS03175	COG1505	serine-type exopeptidase activity
EBA12_RS03185	COG0436	Aminotransferase
EBA12_RS03195	COG2832	Protein of unknown function (DUF454)
EBA12_RS03215	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EBA12_RS03225	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EBA12_RS03260	COG3300	MHYT domain
EBA12_RS03260	COG5001	Diguanylate cyclase
EBA12_RS03265	COG0308	aminopeptidase N
EBA12_RS03280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA12_RS03285	COG1077	Cell shape determining protein MreB Mrl
EBA12_RS03290	COG1792	Involved in formation and maintenance of cell shape
EBA12_RS03305	COG0772	Belongs to the SEDS family
EBA12_RS03330	COG2951	lytic endotransglycosylase activity
EBA12_RS03335	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EBA12_RS03340	COG1686	Belongs to the peptidase S11 family
EBA12_RS03355	COG2921	Belongs to the UPF0250 family
EBA12_RS03380	COG1056	cytidyltransferase-related domain
EBA12_RS03380	COG1051	belongs to the nudix hydrolase family
EBA12_RS03415	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EBA12_RS03420	COG0673	inositol 2-dehydrogenase activity
EBA12_RS03425	COG2823	Periplasmic or secreted lipoprotein
EBA12_RS03430	COG4251	negative regulation of phosphorylation
EBA12_RS03435	COG0784	Response regulator, receiver
EBA12_RS03440	COG4191	Histidine kinase
EBA12_RS03445	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EBA12_RS03470	COG3039	Transposase
EBA12_RS03490	COG3250	beta-galactosidase activity
EBA12_RS03505	COG2188	Transcriptional regulator
EBA12_RS03515	COG1609	Transcriptional regulator
EBA12_RS03520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA12_RS03525	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EBA12_RS03540	COG1215	transferase activity, transferring glycosyl groups
EBA12_RS03545	COG0726	polysaccharide deacetylase
EBA12_RS03545	COG1649	PFAM Uncharacterised BCR, COG1649
EBA12_RS03565	COG3039	Transposase
EBA12_RS03610	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EBA12_RS03650	COG2205	protein histidine kinase activity
EBA12_RS03680	COG3791	Glutathione-dependent formaldehyde-activating
EBA12_RS03695	COG3039	Transposase
EBA12_RS03710	COG0488	(ABC) transporter
EBA12_RS03730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EBA12_RS03740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EBA12_RS03750	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA12_RS03750	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA12_RS03770	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EBA12_RS03775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBA12_RS03780	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EBA12_RS03810	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EBA12_RS03815	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EBA12_RS03825	COG2205	protein histidine kinase activity
EBA12_RS03830	COG0745	RESPONSE REGULATOR receiver
EBA12_RS03860	COG0277	FAD linked oxidase domain protein
EBA12_RS03870	COG0792	nuclease activity
EBA12_RS03910	COG0275	rRNA processing
EBA12_RS03915	COG3116	cell division
EBA12_RS03930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EBA12_RS03935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA12_RS03950	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBA12_RS03955	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA12_RS03960	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EBA12_RS03975	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EBA12_RS03985	COG1196	nuclear chromosome segregation
EBA12_RS03985	COG0739	heme binding
EBA12_RS03985	COG0741	lytic transglycosylase activity
EBA12_RS04000	COG0494	nUDIX hydrolase
EBA12_RS04015	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EBA12_RS04030	COG3321	synthase
EBA12_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
EBA12_RS04030	COG0604	alcohol dehydrogenase
EBA12_RS04090	COG2226	methyltransferase
EBA12_RS04095	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EBA12_RS04120	COG2826	transposase and inactivated derivatives, IS30 family
EBA12_RS04145	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EBA12_RS04160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA12_RS04170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA12_RS04175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EBA12_RS04185	COG0667	Aldo Keto reductase
EBA12_RS04210	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EBA12_RS04220	COG2175	clavaminate synthase activity
EBA12_RS04230	COG4181	ATPase activity
EBA12_RS04245	COG0642	Histidine kinase
EBA12_RS04260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EBA12_RS04280	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EBA12_RS04300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EBA12_RS04305	COG2967	ApaG domain
EBA12_RS04310	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EBA12_RS04325	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EBA12_RS04340	COG0123	including yeast histone deacetylase and acetoin utilization protein
EBA12_RS04345	COG2096	Adenosyltransferase
EBA12_RS04360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA12_RS04365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA12_RS04385	COG1802	Transcriptional regulator
EBA12_RS04395	COG3384	dioxygenase
EBA12_RS04400	COG0583	DNA-binding transcription factor activity
EBA12_RS04405	COG0318	PFAM AMP-dependent synthetase and ligase
EBA12_RS04415	COG1024	Enoyl-CoA hydratase
EBA12_RS04435	COG3386	PFAM SMP-30 Gluconolaconase
EBA12_RS04485	COG2197	response regulator
EBA12_RS04495	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EBA12_RS04500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EBA12_RS04505	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA12_RS04515	COG0583	DNA-binding transcription factor activity
EBA12_RS04520	COG3634	alkyl hydroperoxide reductase activity
EBA12_RS04530	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA12_RS04570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA12_RS04570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA12_RS04585	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBA12_RS04640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EBA12_RS04650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EBA12_RS04680	COG1295	ribonuclease BN
EBA12_RS04685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA12_RS04690	COG1254	Belongs to the acylphosphatase family
EBA12_RS04705	COG0521	Mo-molybdopterin cofactor biosynthetic process
EBA12_RS04715	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EBA12_RS04720	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EBA12_RS04730	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EBA12_RS04745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EBA12_RS04755	COG0193	aminoacyl-tRNA hydrolase activity
EBA12_RS04760	COG0012	GTP binding
EBA12_RS04795	COG0250	Participates in transcription elongation, termination and antitermination
EBA12_RS04805	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EBA12_RS04810	COG0081	regulation of translation
EBA12_RS04815	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EBA12_RS04825	COG0085	RNA polymerase activity
EBA12_RS04830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EBA12_RS04835	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EBA12_RS04840	COG0049	tRNA binding
EBA12_RS04870	COG0088	Forms part of the polypeptide exit tunnel
EBA12_RS04875	COG0089	rRNA binding
EBA12_RS04880	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EBA12_RS04890	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EBA12_RS04900	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EBA12_RS04905	COG0255	Belongs to the universal ribosomal protein uL29 family
EBA12_RS04910	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EBA12_RS04915	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EBA12_RS04920	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EBA12_RS04955	COG1841	ribosomal large subunit assembly
EBA12_RS04960	COG0200	Binds to the 23S rRNA
EBA12_RS04965	COG0201	protein transport
EBA12_RS04975	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EBA12_RS04980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EBA12_RS04990	COG0203	ribosomal protein L17
EBA12_RS05010	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EBA12_RS05030	COG1217	gtp-binding protein TYPA
EBA12_RS05035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EBA12_RS05045	COG0625	glutathione transferase activity
EBA12_RS05075	COG3039	Transposase
EBA12_RS05095	COG0446	pyridine nucleotide-disulphide oxidoreductase
EBA12_RS05095	COG1902	pentaerythritol trinitrate reductase activity
EBA12_RS05100	COG0604	alcohol dehydrogenase
EBA12_RS05130	COG0156	8-amino-7-oxononanoate synthase activity
EBA12_RS05135	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EBA12_RS05140	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EBA12_RS05145	COG4208	sulfate ABC transporter
EBA12_RS05150	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EBA12_RS05185	COG0406	alpha-ribazole phosphatase activity
EBA12_RS05195	COG0285	dihydrofolate synthase activity
EBA12_RS05215	COG2833	Protein of unknown function (DUF455)
EBA12_RS05240	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBA12_RS05245	COG0671	phosphoesterase, PA-phosphatase related
EBA12_RS05250	COG0438	transferase activity, transferring glycosyl groups
EBA12_RS05260	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EBA12_RS05265	COG5002	protein histidine kinase activity
EBA12_RS05275	COG4783	chaperone-mediated protein folding
EBA12_RS05290	COG0473	3-isopropylmalate dehydrogenase activity
EBA12_RS05330	COG3039	Transposase
EBA12_RS05355	COG0544	peptidyl-prolyl cis-trans isomerase activity
EBA12_RS05395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EBA12_RS05420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA12_RS05435	COG0631	protein serine/threonine phosphatase activity
EBA12_RS05470	COG0859	PFAM glycosyl transferase family 9
EBA12_RS05475	COG3642	lipopolysaccharide core region biosynthetic process
EBA12_RS05480	COG1234	tRNA 3'-trailer cleavage
EBA12_RS05485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EBA12_RS05495	COG0315	cyclic pyranopterin monophosphate synthase activity
EBA12_RS05500	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EBA12_RS05505	COG0314	molybdopterin synthase activity
EBA12_RS05540	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EBA12_RS05550	COG0537	adenosine 5'-monophosphoramidase activity
EBA12_RS05570	COG0714	Associated with various cellular activities
EBA12_RS05590	COG1399	metal-binding, possibly nucleic acid-binding protein
EBA12_RS05615	COG1028	Short-chain dehydrogenase reductase Sdr
EBA12_RS05620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBA12_RS05630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EBA12_RS05635	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EBA12_RS05670	COG3829	transcription factor binding
EBA12_RS05710	COG3039	Transposase
EBA12_RS05790	COG0330	HflC and HflK could
EBA12_RS05795	COG0330	HflC and HflK could
EBA12_RS05805	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EBA12_RS05810	COG0308	aminopeptidase N
EBA12_RS05825	COG0732	type I restriction modification DNA specificity domain
EBA12_RS05840	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EBA12_RS05925	COG0587	DNA-directed DNA polymerase activity
EBA12_RS05945	COG1297	OPT oligopeptide transporter protein
EBA12_RS05965	COG1506	peptidase
EBA12_RS05965	COG0823	Involved in the tonB-independent uptake of proteins
EBA12_RS05975	COG2207	Transcriptional regulator
EBA12_RS05975	COG1917	Cupin 2, conserved barrel domain protein
EBA12_RS06020	COG0753	catalase activity
EBA12_RS06060	COG3551	Protein conserved in bacteria
EBA12_RS06090	COG2194	sulfuric ester hydrolase activity
EBA12_RS06100	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EBA12_RS06105	COG0745	RESPONSE REGULATOR receiver
EBA12_RS06110	COG0642	Histidine kinase
EBA12_RS06120	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EBA12_RS06125	COG2894	cell division
EBA12_RS06140	COG4585	Histidine kinase
EBA12_RS06145	COG2197	response regulator
EBA12_RS06160	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EBA12_RS06185	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EBA12_RS06260	COG2826	transposase and inactivated derivatives, IS30 family
EBA12_RS06285	COG3039	Transposase
EBA12_RS06310	COG3179	chitinase
EBA12_RS06465	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EBA12_RS06480	COG1842	Phage shock protein A
EBA12_RS06505	COG0754	glutathionylspermidine amidase activity
EBA12_RS06585	COG0531	amino acid
EBA12_RS06590	COG2197	response regulator
EBA12_RS06595	COG2267	carboxylic ester hydrolase activity
EBA12_RS06605	COG1113	amino acid transport
EBA12_RS06635	COG3039	Transposase
EBA12_RS06645	COG1294	oxidase, subunit
EBA12_RS06655	COG2239	Acts as a magnesium transporter
EBA12_RS06665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA12_RS06670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA12_RS06685	COG3039	Transposase
EBA12_RS06700	COG1660	Displays ATPase and GTPase activities
EBA12_RS06710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA12_RS06725	COG1137	ATPase activity
EBA12_RS06730	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EBA12_RS06740	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EBA12_RS06750	COG0271	Belongs to the BolA IbaG family
EBA12_RS06755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EBA12_RS06780	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EBA12_RS06795	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EBA12_RS06805	COG0628	permease
EBA12_RS06815	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EBA12_RS06820	COG3178	'Phosphotransferase
EBA12_RS06830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA12_RS06835	COG1555	photosystem II stabilization
EBA12_RS06855	COG3039	Transposase
EBA12_RS06865	COG2146	nitrite reductase [NAD(P)H] activity
EBA12_RS06875	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EBA12_RS06880	COG0719	Fe-S assembly protein
EBA12_RS06885	COG0396	ATPase activity
EBA12_RS06890	COG0719	Fe-S assembly protein
EBA12_RS06895	COG1959	2 iron, 2 sulfur cluster binding
EBA12_RS06950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EBA12_RS06985	COG0519	Catalyzes the synthesis of GMP from XMP
EBA12_RS07000	COG1678	Uncharacterized ACR, COG1678
EBA12_RS07005	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EBA12_RS07020	COG1764	response to oxidative stress
EBA12_RS07030	COG0384	phenazine biosynthesis protein PhzF
EBA12_RS07040	COG0527	aspartate kinase activity
EBA12_RS07070	COG3039	Transposase
EBA12_RS07080	COG0142	geranyltranstransferase activity
EBA12_RS07085	COG0629	single-stranded DNA binding
EBA12_RS07090	COG4251	negative regulation of phosphorylation
EBA12_RS07090	COG2203	Gaf domain
EBA12_RS07090	COG3706	GGDEF domain
EBA12_RS07090	COG5001	Diguanylate cyclase
EBA12_RS07135	COG2879	small protein
EBA12_RS07140	COG1966	Carbon starvation protein
EBA12_RS07145	COG1741	Belongs to the pirin family
EBA12_RS07240	COG1515	deoxyribonuclease V activity
EBA12_RS07260	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EBA12_RS07265	COG2200	EAL domain
EBA12_RS07265	COG2199	diguanylate cyclase activity
EBA12_RS07265	COG2202	Pas domain
EBA12_RS07270	COG0835	chemotaxis
EBA12_RS07275	COG0840	transmembrane signaling receptor activity
EBA12_RS07285	COG2198	Histidine kinase
EBA12_RS07285	COG0643	Histidine kinase
EBA12_RS07300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EBA12_RS07310	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EBA12_RS07345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EBA12_RS07350	COG0735	belongs to the Fur family
EBA12_RS07380	COG2826	transposase and inactivated derivatives, IS30 family
EBA12_RS07470	COG3039	Transposase
EBA12_RS07530	COG5001	Diguanylate cyclase
EBA12_RS07530	COG5002	protein histidine kinase activity
EBA12_RS07535	COG1187	pseudouridine synthase activity
EBA12_RS07555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EBA12_RS07565	COG0475	glutathione-regulated potassium exporter activity
EBA12_RS07570	COG5000	phosphorelay sensor kinase activity
EBA12_RS07570	COG5002	protein histidine kinase activity
EBA12_RS07575	COG0745	RESPONSE REGULATOR receiver
EBA12_RS07580	COG1538	Outer membrane efflux protein
EBA12_RS07605	COG1132	(ABC) transporter
EBA12_RS07630	COG3039	Transposase
EBA12_RS07675	COG3118	belongs to the thioredoxin family
EBA12_RS07705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EBA12_RS07725	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EBA12_RS07750	COG2968	Membrane
EBA12_RS07765	COG3164	Protein of unknown function
EBA12_RS07775	COG0312	modulator of DNA gyrase
EBA12_RS07780	COG3028	Belongs to the UPF0307 family
EBA12_RS07785	COG0312	modulator of DNA gyrase
EBA12_RS07800	COG4104	PAAR repeat-containing protein
EBA12_RS07810	COG0142	geranyltranstransferase activity
EBA12_RS07815	COG1722	exodeoxyribonuclease VII activity
EBA12_RS07820	COG0037	tRNA processing
EBA12_RS07825	COG1785	Belongs to the alkaline phosphatase family
EBA12_RS07830	COG1301	dicarboxylic acid transport
EBA12_RS07835	COG4106	trans-aconitate 2-methyltransferase activity
EBA12_RS07850	COG0791	NLP P60 protein
EBA12_RS07855	COG0791	NLP P60 protein
EBA12_RS07860	COG1047	Peptidyl-prolyl cis-trans
EBA12_RS07865	COG2311	Membrane
EBA12_RS07870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA12_RS07900	COG3039	Transposase
EBA12_RS07910	COG2826	transposase and inactivated derivatives, IS30 family
EBA12_RS07940	COG2826	transposase and inactivated derivatives, IS30 family
EBA12_RS07945	COG3039	Transposase
EBA12_RS07960	COG0489	protein tyrosine kinase activity
EBA12_RS07970	COG0717	Belongs to the dCTP deaminase family
EBA12_RS07985	COG3039	Transposase
EBA12_RS08005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EBA12_RS08015	COG3039	Transposase
EBA12_RS08025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA12_RS08040	COG2826	transposase and inactivated derivatives, IS30 family
EBA12_RS08050	COG0433	COG0433 Predicted ATPase
EBA12_RS08080	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA12_RS08085	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EBA12_RS08090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBA12_RS08095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EBA12_RS08115	COG0101	tRNA pseudouridine synthase activity
EBA12_RS08120	COG0135	phosphoribosylanthranilate isomerase activity
EBA12_RS08130	COG0133	tryptophan synthase activity
EBA12_RS08150	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EBA12_RS08155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBA12_RS08210	COG0149	triose-phosphate isomerase activity
EBA12_RS08225	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA12_RS08235	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA12_RS08240	COG0649	NAD binding
EBA12_RS08245	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EBA12_RS08250	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EBA12_RS08255	COG1034	ATP synthesis coupled electron transport
EBA12_RS08260	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EBA12_RS08265	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA12_RS08290	COG1007	ATP synthesis coupled electron transport
EBA12_RS08300	COG0779	Required for maturation of 30S ribosomal subunits
EBA12_RS08305	COG0195	Participates in both transcription termination and antitermination
EBA12_RS08310	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EBA12_RS08325	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EBA12_RS08330	COG1185	polyribonucleotide nucleotidyltransferase activity
EBA12_RS08365	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA12_RS08375	COG2095	MarC family integral membrane protein
EBA12_RS08390	COG3039	Transposase
EBA12_RS08395	COG1611	Belongs to the LOG family
EBA12_RS08435	COG4969	Belongs to the N-Me-Phe pilin family
EBA12_RS08440	COG0556	nucleotide-excision repair
EBA12_RS08470	COG3723	Recombinational DNA repair protein, rece pathway
EBA12_RS08570	COG0270	DNA (cytosine-5-)-methyltransferase activity
EBA12_RS08920	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EBA12_RS08930	COG2986	histidine ammonia-lyase
EBA12_RS08935	COG1228	amidohydrolase
EBA12_RS08980	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EBA12_RS08985	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EBA12_RS08990	COG1605	Chorismate mutase
EBA12_RS08990	COG0077	Prephenate dehydratase
EBA12_RS08995	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EBA12_RS09020	COG3039	Transposase
EBA12_RS09030	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EBA12_RS09045	COG0583	DNA-binding transcription factor activity
EBA12_RS09060	COG2336	PFAM SpoVT AbrB
EBA12_RS09100	COG0840	transmembrane signaling receptor activity
EBA12_RS09125	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EBA12_RS09130	COG0784	Response regulator, receiver
EBA12_RS09130	COG4191	Histidine kinase
EBA12_RS09145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA12_RS09165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA12_RS09180	COG1595	DNA-templated transcription, initiation
EBA12_RS09230	COG2244	polysaccharide biosynthetic process
EBA12_RS09260	COG2264	protein methyltransferase activity
EBA12_RS09270	COG0438	transferase activity, transferring glycosyl groups
EBA12_RS09285	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EBA12_RS09290	COG1132	(ABC) transporter
EBA12_RS09300	COG0477	Major facilitator Superfamily
EBA12_RS09320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBA12_RS09335	COG1253	flavin adenine dinucleotide binding
EBA12_RS09350	COG0306	phosphate transporter
EBA12_RS09380	COG0504	CTP synthase activity
EBA12_RS09385	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EBA12_RS09390	COG0148	phosphopyruvate hydratase activity
EBA12_RS09395	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EBA12_RS09410	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EBA12_RS09420	COG2840	Smr protein MutS2
EBA12_RS09425	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EBA12_RS09430	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBA12_RS09435	COG1238	metal cluster binding
EBA12_RS09450	COG1534	Rna-binding protein
EBA12_RS09455	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EBA12_RS09465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EBA12_RS09480	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EBA12_RS09485	COG1546	Belongs to the CinA family
EBA12_RS09500	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EBA12_RS09510	COG2137	regulation of response to DNA damage stimulus
EBA12_RS09515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EBA12_RS09520	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EBA12_RS09570	COG1741	Belongs to the pirin family
EBA12_RS09575	COG0583	DNA-binding transcription factor activity
EBA12_RS09600	COG0351	phosphomethylpyrimidine kinase
EBA12_RS09600	COG0352	thiamine-phosphate diphosphorylase activity
EBA12_RS09610	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EBA12_RS09615	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EBA12_RS09630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA12_RS09640	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EBA12_RS09645	COG3734	2-keto-3-deoxy-galactonokinase
EBA12_RS09655	COG4948	Mandelate Racemase Muconate Lactonizing
EBA12_RS09660	COG0800	Aldolase
EBA12_RS09685	COG1070	Carbohydrate kinase
EBA12_RS09695	COG0477	Major facilitator Superfamily
EBA12_RS09715	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA12_RS09720	COG1469	GTP cyclohydrolase I activity
EBA12_RS09730	COG0617	tRNA 3'-terminal CCA addition
EBA12_RS09750	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EBA12_RS09780	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA12_RS09800	COG5001	Diguanylate cyclase
EBA12_RS09800	COG4251	negative regulation of phosphorylation
EBA12_RS09800	COG3706	GGDEF domain
EBA12_RS09800	COG2203	Gaf domain
EBA12_RS09810	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA12_RS09820	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EBA12_RS09835	COG0671	phosphoesterase, PA-phosphatase related
EBA12_RS09855	COG1794	racemase activity, acting on amino acids and derivatives
EBA12_RS09865	COG0697	spore germination
EBA12_RS09870	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EBA12_RS09895	COG1012	belongs to the aldehyde dehydrogenase family
EBA12_RS09960	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EBA12_RS09975	COG0124	histidyl-tRNA synthetase
EBA12_RS09995	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EBA12_RS10010	COG0131	Imidazoleglycerol-phosphate dehydratase
EBA12_RS10010	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EBA12_RS10020	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EBA12_RS10030	COG0140	phosphoribosyl-ATP diphosphatase activity
EBA12_RS10030	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EBA12_RS10050	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EBA12_RS10055	COG0235	Class ii aldolase
EBA12_RS10060	COG0531	amino acid
EBA12_RS10065	COG0531	amino acid
EBA12_RS10075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EBA12_RS10080	COG0277	FAD linked oxidase domain protein
EBA12_RS10105	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EBA12_RS10160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBA12_RS10165	COG2258	MOSC domain
EBA12_RS10170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EBA12_RS10175	COG0505	Belongs to the CarA family
EBA12_RS10185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EBA12_RS10190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA12_RS10200	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EBA12_RS10215	COG3279	Response regulator of the LytR AlgR family
EBA12_RS10240	COG2205	protein histidine kinase activity
EBA12_RS10240	COG0784	Response regulator, receiver
EBA12_RS10240	COG2198	Histidine kinase
EBA12_RS10245	COG1024	Enoyl-CoA hydratase
EBA12_RS10250	COG0318	PFAM AMP-dependent synthetase and ligase
EBA12_RS10280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA12_RS10310	COG0840	transmembrane signaling receptor activity
EBA12_RS10320	COG0835	chemotaxis
EBA12_RS10335	COG0840	transmembrane signaling receptor activity
EBA12_RS10340	COG0840	transmembrane signaling receptor activity
EBA12_RS10345	COG0840	transmembrane signaling receptor activity
EBA12_RS10360	COG0840	transmembrane signaling receptor activity
EBA12_RS10370	COG0840	transmembrane signaling receptor activity
EBA12_RS10375	COG0840	transmembrane signaling receptor activity
EBA12_RS10405	COG0840	transmembrane signaling receptor activity
EBA12_RS10410	COG2826	transposase and inactivated derivatives, IS30 family
EBA12_RS10430	COG0745	RESPONSE REGULATOR receiver
EBA12_RS10440	COG0835	chemotaxis
EBA12_RS10445	COG1192	Involved in chromosome partitioning
EBA12_RS10450	COG1360	Flagellar Motor Protein
EBA12_RS10455	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EBA12_RS10475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA12_RS10515	COG3039	Transposase
EBA12_RS10580	COG0784	Response regulator, receiver
EBA12_RS10580	COG0643	Histidine kinase
EBA12_RS10580	COG2198	Histidine kinase
EBA12_RS10635	COG1684	flagellar biosynthetic protein fliR
EBA12_RS10650	COG3190	flagellar
EBA12_RS10700	COG1677	Flagellar hook-basal body complex protein FliE
EBA12_RS10735	COG1028	Short-chain dehydrogenase reductase Sdr
EBA12_RS10745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA12_RS10765	COG2201	protein-glutamate methylesterase activity
EBA12_RS10795	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EBA12_RS10800	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EBA12_RS10815	COG3951	Flagellar rod assembly protein muramidase FlgJ
EBA12_RS10815	COG1705	Flagellar rod assembly protein muramidase FlgJ
EBA12_RS10820	COG1706	bacterial-type flagellum-dependent cell motility
EBA12_RS10825	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EBA12_RS10840	COG4787	bacterial-type flagellum-dependent cell motility
EBA12_RS10850	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EBA12_RS10855	COG1558	bacterial-type flagellum-dependent cell motility
EBA12_RS10865	COG0784	Response regulator, receiver
EBA12_RS10865	COG0835	chemotaxis
EBA12_RS10885	COG5002	protein histidine kinase activity
EBA12_RS10895	COG4585	Histidine kinase
EBA12_RS10930	COG0482	sulfurtransferase activity
EBA12_RS10945	COG0542	response to heat
EBA12_RS10970	COG0492	ferredoxin-NADP+ reductase activity
EBA12_RS10975	COG1674	ftsk spoiiie
EBA12_RS11000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EBA12_RS11020	COG0038	chloride channel
EBA12_RS11025	COG0183	Belongs to the thiolase family
EBA12_RS11030	COG1024	Enoyl-CoA hydratase
EBA12_RS11030	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA12_RS11045	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EBA12_RS11065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA12_RS11070	COG1160	GTP binding
EBA12_RS11075	COG0303	'Molybdopterin
EBA12_RS11085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EBA12_RS11095	COG2826	transposase and inactivated derivatives, IS30 family
EBA12_RS11120	COG0746	molybdenum cofactor guanylyltransferase activity
EBA12_RS11145	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EBA12_RS11145	COG1648	precorrin-2 dehydrogenase activity
EBA12_RS11185	COG3039	Transposase
EBA12_RS11210	COG5001	Diguanylate cyclase
EBA12_RS11230	COG4566	intracellular signal transduction
EBA12_RS11360	COG1024	Enoyl-CoA hydratase
EBA12_RS11365	COG1024	Enoyl-CoA hydratase
EBA12_RS11375	COG1024	Enoyl-CoA hydratase
EBA12_RS11390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EBA12_RS11500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA12_RS11505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA12_RS11555	COG1858	cytochrome C peroxidase
EBA12_RS11585	COG0515	serine threonine protein kinase
EBA12_RS11590	COG0631	protein serine/threonine phosphatase activity
EBA12_RS11650	COG2826	transposase and inactivated derivatives, IS30 family
EBA12_RS11665	COG3039	Transposase
EBA12_RS11750	COG3039	Transposase
EBA12_RS11765	COG2154	pterin-4-alpha-carbinolamine dehydratase
EBA12_RS11780	COG3064	Membrane
EBA12_RS11790	COG1530	ribonuclease E activity
EBA12_RS11805	COG1054	Belongs to the UPF0176 family
EBA12_RS11825	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EBA12_RS11865	COG0322	excinuclease ABC activity
EBA12_RS11875	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBA12_RS11885	COG1663	tetraacyldisaccharide 4'-kinase activity
EBA12_RS11900	COG0811	peptide transport
EBA12_RS11925	COG4591	ABC-type transport system involved in lipoprotein release permease component
EBA12_RS11940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EBA12_RS11955	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EBA12_RS11970	COG0354	folic acid binding
EBA12_RS11985	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA12_RS11995	COG0363	glucosamine-6-phosphate deaminase activity
EBA12_RS12000	COG0129	dihydroxy-acid dehydratase activity
EBA12_RS12005	COG0800	Aldolase
EBA12_RS12085	COG0784	Response regulator, receiver
EBA12_RS12085	COG2205	protein histidine kinase activity
EBA12_RS12100	COG2183	response to ionizing radiation
EBA12_RS12110	COG0723	plastoquinol--plastocyanin reductase activity
EBA12_RS12110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA12_RS12125	COG3243	poly(R)-hydroxyalkanoic acid synthase
EBA12_RS12135	COG1183	phosphatidylcholine synthase activity
EBA12_RS12140	COG1028	Short-chain dehydrogenase reductase Sdr
EBA12_RS12155	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EBA12_RS12165	COG0668	transmembrane transport
EBA12_RS12185	COG1914	H( )-stimulated, divalent metal cation uptake system
EBA12_RS12215	COG0583	DNA-binding transcription factor activity
EBA12_RS12240	COG0583	DNA-binding transcription factor activity
EBA12_RS12245	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA12_RS12250	COG3002	Belongs to the UPF0753 family
EBA12_RS12255	COG0519	Catalyzes the synthesis of GMP from XMP
EBA12_RS12255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA12_RS12265	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EBA12_RS12280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EBA12_RS12290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA12_RS12295	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EBA12_RS12305	COG0776	regulation of translation
EBA12_RS12310	COG0539	negative regulation of cytoplasmic translation
EBA12_RS12315	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EBA12_RS12330	COG2957	Belongs to the agmatine deiminase family
EBA12_RS12340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA12_RS12365	COG0395	ABC-type sugar transport system, permease component
EBA12_RS12370	COG1175	transmembrane transport
EBA12_RS12400	COG2350	Protein conserved in bacteria
EBA12_RS12405	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EBA12_RS12410	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EBA12_RS12415	COG1187	pseudouridine synthase activity
EBA12_RS12435	COG0436	Aminotransferase
EBA12_RS12440	COG4133	protoheme IX ABC transporter activity
EBA12_RS12490	COG1278	Cold shock
EBA12_RS12500	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EBA12_RS12505	COG4988	ABC transporter
EBA12_RS12515	COG1271	oxidase subunit
EBA12_RS12570	COG0165	Argininosuccinate lyase
EBA12_RS12585	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EBA12_RS12590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA12_RS12595	COG0137	argininosuccinate synthase activity
EBA12_RS12600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EBA12_RS12615	COG2166	iron-sulfur cluster assembly
EBA12_RS12640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EBA12_RS12655	COG4302	ethanolamine ammonia-lyase activity
EBA12_RS12670	COG4677	pectinesterase activity
EBA12_RS12695	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EBA12_RS12700	COG0402	S-adenosylhomocysteine deaminase activity
EBA12_RS12720	COG1509	lysine 2,3-aminomutase activity
EBA12_RS12725	COG3300	MHYT domain
EBA12_RS12725	COG5001	Diguanylate cyclase
EBA12_RS12740	COG0483	inositol monophosphate 1-phosphatase activity
EBA12_RS12745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA12_RS12770	COG0488	(ABC) transporter
EBA12_RS12775	COG0513	Belongs to the DEAD box helicase family
EBA12_RS12785	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EBA12_RS12795	COG0625	glutathione transferase activity
EBA12_RS12805	COG1671	Belongs to the UPF0178 family
EBA12_RS12810	COG4681	YaeQ
EBA12_RS12815	COG2081	HI0933 family
EBA12_RS12820	COG5001	Diguanylate cyclase
EBA12_RS12820	COG1716	ATPase activity
EBA12_RS12825	COG0501	Belongs to the peptidase M48B family
EBA12_RS12835	COG1028	Short-chain dehydrogenase reductase Sdr
EBA12_RS12855	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EBA12_RS12860	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA12_RS12865	COG0802	atpase or kinase
EBA12_RS12870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EBA12_RS12870	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EBA12_RS12875	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA12_RS12895	COG3039	Transposase
EBA12_RS12905	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA12_RS12950	COG0835	chemotaxis
EBA12_RS12955	COG0840	transmembrane signaling receptor activity
EBA12_RS12985	COG2969	positive regulation of protein catabolic process
EBA12_RS12990	COG0625	glutathione transferase activity
EBA12_RS12995	COG2857	Cytochrome c1
EBA12_RS13000	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EBA12_RS13005	COG0723	plastoquinol--plastocyanin reductase activity
EBA12_RS13015	COG0741	lytic transglycosylase activity
EBA12_RS13040	COG1702	phosphate starvation-inducible protein PhoH
EBA12_RS13060	COG4535	Mg2 and Co2 transporter CorC
EBA12_RS13075	COG1012	belongs to the aldehyde dehydrogenase family
EBA12_RS13080	COG1177	transmembrane transport
EBA12_RS13085	COG1176	ABC-type spermidine putrescine transport system, permease component I
EBA12_RS13095	COG3842	ATPase activity
EBA12_RS13125	COG3039	Transposase
EBA12_RS13150	COG0174	glutamine synthetase
EBA12_RS13155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA12_RS13165	COG0477	Major facilitator Superfamily
EBA12_RS13175	COG0243	molybdopterin cofactor binding
EBA12_RS13185	COG2223	nitrite transmembrane transporter activity
EBA12_RS13195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EBA12_RS13200	COG1121	(ABC) transporter
EBA12_RS13210	COG2733	membrane
EBA12_RS13215	COG0784	Response regulator, receiver
EBA12_RS13215	COG2205	protein histidine kinase activity
EBA12_RS13215	COG5002	protein histidine kinase activity
EBA12_RS13225	COG3039	Transposase
EBA12_RS13275	COG3039	Transposase
EBA12_RS13285	COG2902	Dehydrogenase
EBA12_RS13295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA12_RS13300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA12_RS13315	COG1609	Transcriptional regulator
EBA12_RS13320	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA12_RS13320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA12_RS13325	COG1105	Belongs to the carbohydrate kinase PfkB family
EBA12_RS13330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA12_RS13330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA12_RS13380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBA12_RS13390	COG1862	Preprotein translocase
EBA12_RS13395	COG0343	queuine tRNA-ribosyltransferase activity
EBA12_RS13460	COG0405	Gamma-glutamyltransferase
EBA12_RS13465	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EBA12_RS13480	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EBA12_RS13485	COG0742	ribosomal rna small subunit methyltransferase
EBA12_RS13490	COG0326	Molecular chaperone. Has ATPase activity
EBA12_RS13535	COG4206	TonB-dependent receptor
EBA12_RS13590	COG3039	Transposase
EBA12_RS13595	COG3039	Transposase
EBA12_RS13605	COG0531	amino acid
EBA12_RS13620	COG0006	proline dipeptidase activity
EBA12_RS13630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA12_RS13645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA12_RS13650	COG3938	Belongs to the proline racemase family
EBA12_RS13660	COG0552	protein localization to endoplasmic reticulum
EBA12_RS13675	COG1194	a g-specific adenine glycosylase
EBA12_RS13685	COG0784	Response regulator, receiver
EBA12_RS13685	COG4191	Histidine kinase
EBA12_RS13690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EBA12_RS13715	COG3040	lipid binding
EBA12_RS13725	COG1960	acyl-CoA dehydrogenase activity
EBA12_RS13735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EBA12_RS13765	COG0438	transferase activity, transferring glycosyl groups
EBA12_RS13775	COG0438	transferase activity, transferring glycosyl groups
EBA12_RS13780	COG0438	transferase activity, transferring glycosyl groups
EBA12_RS13835	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EBA12_RS13850	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EBA12_RS13875	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EBA12_RS13890	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EBA12_RS13895	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EBA12_RS13900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EBA12_RS13905	COG3115	cell septum assembly
EBA12_RS13925	COG0360	Binds together with S18 to 16S ribosomal RNA
EBA12_RS13930	COG0316	Belongs to the HesB IscA family
EBA12_RS13965	COG0288	reversible hydration of carbon dioxide
EBA12_RS13990	COG3844	kynureninase activity
EBA12_RS14000	COG2925	Exonuclease
EBA12_RS14010	COG0667	Aldo Keto reductase
EBA12_RS14040	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBA12_RS14040	COG0116	Belongs to the methyltransferase superfamily
EBA12_RS14085	COG0494	nUDIX hydrolase
EBA12_RS14095	COG1024	Enoyl-CoA hydratase
EBA12_RS14105	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EBA12_RS14110	COG0659	secondary active sulfate transmembrane transporter activity
EBA12_RS14135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EBA12_RS14140	COG0573	inorganic phosphate transmembrane transporter activity
EBA12_RS14155	COG0704	Plays a role in the regulation of phosphate uptake
EBA12_RS14165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA12_RS14175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA12_RS14190	COG0557	exoribonuclease II activity
EBA12_RS14220	COG1960	acyl-CoA dehydrogenase activity
EBA12_RS14225	COG2226	methyltransferase
EBA12_RS14230	COG1410	methionine synthase
EBA12_RS14230	COG0646	methionine synthase
EBA12_RS14235	COG0646	methionine synthase
EBA12_RS14235	COG1410	methionine synthase
EBA12_RS14245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA12_RS14255	COG1609	Transcriptional regulator
EBA12_RS14270	COG2900	Belongs to the SlyX family
EBA12_RS14285	COG0386	Belongs to the glutathione peroxidase family
EBA12_RS14295	COG1725	Transcriptional regulator
EBA12_RS14300	COG1131	(ABC) transporter
EBA12_RS14340	COG3039	Transposase
EBA12_RS14370	COG2850	peptidyl-arginine hydroxylation
EBA12_RS14405	COG1132	(ABC) transporter
EBA12_RS14435	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EBA12_RS14445	COG0484	heat shock protein binding
EBA12_RS14450	COG0443	Heat shock 70 kDa protein
EBA12_RS14455	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EBA12_RS14465	COG0497	DNA recombination
EBA12_RS14475	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA12_RS14485	COG2914	Belongs to the UPF0125 (RnfH) family
EBA12_RS14495	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EBA12_RS14520	COG3039	Transposase
EBA12_RS14565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EBA12_RS14580	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EBA12_RS14590	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EBA12_RS14595	COG0174	glutamine synthetase
EBA12_RS14660	COG0415	Belongs to the DNA photolyase family
EBA12_RS14665	COG0305	Participates in initiation and elongation during chromosome replication
EBA12_RS14675	COG0367	asparagine synthase
EBA12_RS14705	COG0084	hydrolase, TatD family'
EBA12_RS14710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EBA12_RS14750	COG0840	transmembrane signaling receptor activity
EBA12_RS14765	COG3039	Transposase
EBA12_RS14780	COG3039	Transposase
EBA12_RS14810	COG0386	Belongs to the glutathione peroxidase family
EBA12_RS14910	COG2814	Major facilitator Superfamily
EBA12_RS14915	COG1566	PFAM secretion protein HlyD family protein
EBA12_RS14930	COG2207	Transcriptional regulator
EBA12_RS14960	COG4774	siderophore transport
EBA12_RS14970	COG0367	asparagine synthase
EBA12_RS14975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA12_RS14985	COG1393	Belongs to the ArsC family
EBA12_RS15045	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EBA12_RS15060	COG0233	cytoplasmic translational termination
EBA12_RS15070	COG0575	Belongs to the CDS family
EBA12_RS15075	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EBA12_RS15080	COG0750	zinc metalloprotease
EBA12_RS15100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBA12_RS15105	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBA12_RS15125	COG0825	malonyl-CoA metabolic process
EBA12_RS15150	COG1981	membrane
EBA12_RS15200	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA12_RS15215	COG2040	homocysteine
EBA12_RS15220	COG0833	amino acid
EBA12_RS15225	COG0346	lactoylglutathione lyase activity
EBA12_RS15235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBA12_RS15235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBA12_RS15245	COG2878	Part of a membrane complex involved in electron transport
EBA12_RS15265	COG1595	DNA-templated transcription, initiation
EBA12_RS15290	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA12_RS15305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA12_RS15310	COG0251	oxidation-reduction process
EBA12_RS15320	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EBA12_RS15320	COG0392	lysyltransferase activity
EBA12_RS15360	COG2814	Major facilitator Superfamily
EBA12_RS15365	COG1902	pentaerythritol trinitrate reductase activity
EBA12_RS15380	COG2824	Alkylphosphonate utilization operon protein PhnA
EBA12_RS15390	COG1047	Peptidyl-prolyl cis-trans
EBA12_RS15430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EBA12_RS15445	COG1451	nucleotide metabolic process
EBA12_RS15465	COG0183	Belongs to the thiolase family
EBA12_RS15495	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EBA12_RS15495	COG1793	dna ligase
EBA12_RS15505	COG1793	dna ligase
EBA12_RS15510	COG1201	RNA secondary structure unwinding
EBA12_RS15530	COG1278	Cold shock
EBA12_RS15535	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EBA12_RS15550	COG3046	protein related to deoxyribodipyrimidine photolyase
EBA12_RS15555	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EBA12_RS15565	COG2954	triphosphatase activity
EBA12_RS15580	COG1381	Involved in DNA repair and RecF pathway recombination
EBA12_RS15610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA12_RS15625	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA12_RS15625	COG1024	Enoyl-CoA hydratase
EBA12_RS15645	COG1024	Enoyl-CoA hydratase
EBA12_RS15650	COG1960	acyl-CoA dehydrogenase activity
EBA12_RS15725	COG2353	YceI-like domain
EBA12_RS15750	COG1760	l-serine dehydratase
EBA12_RS15760	COG0626	cystathionine gamma-synthase activity
EBA12_RS15765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA12_RS15770	COG0739	heme binding
EBA12_RS15780	COG1272	protein, Hemolysin III
EBA12_RS15800	COG0516	GMP reductase activity
EBA12_RS15800	COG0517	IMP dehydrogenase activity
EBA12_RS15805	COG0463	Glycosyl transferase, family 2
EBA12_RS15815	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EBA12_RS15825	COG4771	TonB-dependent receptor
EBA12_RS15830	COG1309	transcriptional regulator
EBA12_RS15840	COG1960	acyl-CoA dehydrogenase activity
EBA12_RS15870	COG0509	glycine decarboxylation via glycine cleavage system
EBA12_RS15885	COG0330	HflC and HflK could
EBA12_RS15895	COG1742	UPF0060 membrane protein
EBA12_RS15900	COG3956	TIGRFAM MazG family protein
EBA12_RS15910	COG0494	nUDIX hydrolase
EBA12_RS15920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EBA12_RS15925	COG0837	glucose binding
EBA12_RS15940	COG3858	chitin binding
EBA12_RS15940	COG1388	LysM domain
EBA12_RS15960	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA12_RS15985	COG2801	Transposase and inactivated derivatives
EBA12_RS15995	COG2826	transposase and inactivated derivatives, IS30 family
EBA12_RS16010	COG3039	Transposase
EBA12_RS16070	COG3537	Alpha-1,2-mannosidase
EBA12_RS16115	COG3142	Participates in the control of copper homeostasis
EBA12_RS16120	COG1446	asparaginase
EBA12_RS16130	COG2304	oxidoreductase activity
EBA12_RS16155	COG0643	Histidine kinase
EBA12_RS16155	COG0784	Response regulator, receiver
EBA12_RS16155	COG2198	Histidine kinase
EBA12_RS16160	COG0840	transmembrane signaling receptor activity
EBA12_RS16165	COG0835	chemotaxis
EBA12_RS16180	COG0189	ligase activity
EBA12_RS16190	COG1397	ADP-ribosylglycohydrolase
EBA12_RS16200	COG1199	ATP-dependent helicase activity
EBA12_RS16210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EBA12_RS16215	COG1215	transferase activity, transferring glycosyl groups
EBA12_RS16225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA12_RS16275	COG1643	Atp-dependent helicase
EBA12_RS16280	COG0783	Belongs to the Dps family
EBA12_RS16290	COG0514	ATP-dependent DNA helicase (RecQ)
EBA12_RS16305	COG3039	Transposase
EBA12_RS16320	COG1187	pseudouridine synthase activity
EBA12_RS16360	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EBA12_RS16370	COG0602	queuosine metabolic process
EBA12_RS16380	COG2885	chlorophyll binding
EBA12_RS16385	COG0823	Involved in the tonB-independent uptake of proteins
EBA12_RS16395	COG0848	biopolymer transport protein
EBA12_RS16405	COG0824	Thioesterase
EBA12_RS16410	COG2255	four-way junction helicase activity
EBA12_RS16425	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EBA12_RS16450	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EBA12_RS16465	COG0477	Major facilitator Superfamily
EBA12_RS16500	COG0488	(ABC) transporter
EBA12_RS16530	COG4651	solute:proton antiporter activity
EBA12_RS16530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EBA12_RS16575	COG4772	TonB-dependent receptor
EBA12_RS16585	COG4264	IucA IucC family
EBA12_RS16590	COG2814	Major facilitator Superfamily
EBA12_RS16600	COG0019	diaminopimelate decarboxylase activity
EBA12_RS16655	COG4206	TonB-dependent receptor
EBA12_RS16690	COG0542	response to heat
EBA12_RS16715	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EBA12_RS16725	COG0534	Mate efflux family protein
EBA12_RS16740	COG0336	Belongs to the RNA methyltransferase TrmD family
EBA12_RS16745	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EBA12_RS16750	COG0228	four-way junction DNA binding
EBA12_RS16775	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EBA12_RS16785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA12_RS16825	COG2172	sigma factor antagonist activity
EBA12_RS16830	COG1366	Belongs to the anti-sigma-factor antagonist family
EBA12_RS16835	COG1366	Belongs to the anti-sigma-factor antagonist family
EBA12_RS16845	COG0326	Molecular chaperone. Has ATPase activity
EBA12_RS16850	COG2207	Transcriptional regulator
EBA12_RS16905	COG3209	COG3209 Rhs family protein
EBA12_RS16920	COG3209	COG3209 Rhs family protein
EBA12_RS16940	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EBA12_RS16945	COG1845	cytochrome c oxidase, subunit III
EBA12_RS16950	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EBA12_RS16965	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EBA12_RS16970	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EBA12_RS16985	COG0728	peptidoglycan biosynthetic process
EBA12_RS16990	COG0268	Binds directly to 16S ribosomal RNA
EBA12_RS16995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EBA12_RS17000	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EBA12_RS17010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EBA12_RS17015	COG0824	Thioesterase
EBA12_RS17030	COG1946	Acyl-CoA thioesterase
EBA12_RS17040	COG1595	DNA-templated transcription, initiation
EBA12_RS17055	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EBA12_RS17095	COG1877	trehalose-phosphatase activity
EBA12_RS17100	COG3387	PFAM Glycoside hydrolase 15-related
EBA12_RS17135	COG0564	pseudouridine synthase activity
EBA12_RS17140	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA12_RS17145	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EBA12_RS17145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA12_RS17160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EBA12_RS17165	COG0045	succinate-CoA ligase (ADP-forming) activity
EBA12_RS17205	COG2194	sulfuric ester hydrolase activity
EBA12_RS17210	COG4969	Belongs to the N-Me-Phe pilin family
EBA12_RS17220	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EBA12_RS17225	COG0237	dephospho-CoA kinase activity
EBA12_RS17230	COG2205	protein histidine kinase activity
EBA12_RS17235	COG0745	RESPONSE REGULATOR receiver
EBA12_RS17255	COG3039	Transposase
EBA12_RS17280	COG3039	Transposase
EBA12_RS17295	COG2801	Transposase and inactivated derivatives
EBA12_RS17305	COG3039	Transposase
EBA12_RS17330	COG2022	thiamine diphosphate biosynthetic process
EBA12_RS17345	COG3273	potassium ion transport
EBA12_RS17345	COG0471	metal ion transport
EBA12_RS17375	COG1970	mechanosensitive ion channel activity
EBA12_RS17410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA12_RS17425	COG0308	aminopeptidase N
EBA12_RS17430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA12_RS17440	COG0529	Catalyzes the synthesis of activated sulfate
EBA12_RS17440	COG2895	sulfate adenylyltransferase (ATP) activity
EBA12_RS17445	COG0175	sulfate reduction
EBA12_RS17450	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA12_RS17455	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EBA12_RS17460	COG0175	sulfate reduction
EBA12_RS17480	COG2198	Histidine kinase
EBA12_RS17480	COG2205	protein histidine kinase activity
EBA12_RS17480	COG0784	Response regulator, receiver
EBA12_RS17520	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EBA12_RS17525	COG3588	fructose-bisphosphate aldolase
EBA12_RS17535	COG0469	pyruvate kinase activity
EBA12_RS17560	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EBA12_RS17570	COG3453	Protein conserved in bacteria
EBA12_RS17570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA12_RS17575	COG0725	ABC transporter, periplasmic molybdate-binding protein
EBA12_RS17580	COG4149	molybdate abc transporter
EBA12_RS17585	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EBA12_RS17605	COG0642	Histidine kinase
EBA12_RS17620	COG1028	Short-chain dehydrogenase reductase Sdr
EBA12_RS17630	COG1022	Amp-dependent synthetase and ligase
EBA12_RS17655	COG1376	ErfK ybiS ycfS ynhG family protein
EBA12_RS17660	COG0739	heme binding
EBA12_RS17675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EBA12_RS17680	COG1301	dicarboxylic acid transport
EBA12_RS17700	COG2304	oxidoreductase activity
EBA12_RS17720	COG0714	Associated with various cellular activities
EBA12_RS17755	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EBA12_RS17790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EBA12_RS17800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA12_RS17820	COG1561	YicC-like family, N-terminal region
EBA12_RS17825	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EBA12_RS17840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EBA12_RS17870	COG0006	proline dipeptidase activity
EBA12_RS17915	COG2912	Transglutaminase-like superfamily
EBA12_RS17920	COG1773	rubredoxin
EBA12_RS17925	COG0352	thiamine-phosphate diphosphorylase activity
EBA12_RS17935	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EBA12_RS17950	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EBA12_RS17995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EBA12_RS18020	COG0671	phosphoesterase, PA-phosphatase related
EBA12_RS18035	COG3781	membrane
EBA12_RS18045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBA12_RS18060	COG3039	Transposase
EBA12_RS18075	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EBA12_RS18085	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EBA12_RS18110	COG3710	Transcriptional regulator
EBA12_RS18115	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EBA12_RS18125	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EBA12_RS18155	COG2226	methyltransferase
EBA12_RS18160	COG0066	3-isopropylmalate dehydratase activity
EBA12_RS18165	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EBA12_RS18185	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBA12_RS18190	COG1538	Outer membrane efflux protein
EBA12_RS18195	COG1519	Transferase
EBA12_RS18200	COG1560	Kdo2-lipid A biosynthetic process
EBA12_RS18220	COG3039	Transposase
EBA12_RS18230	COG2826	transposase and inactivated derivatives, IS30 family
EBA12_RS18295	COG3039	Transposase
EBA12_RS18310	COG0281	malic enzyme
EBA12_RS18310	COG0280	phosphate acetyltransferase
EBA12_RS18330	COG4191	Histidine kinase
EBA12_RS18345	COG0583	DNA-binding transcription factor activity
EBA12_RS18370	COG2197	response regulator
EBA12_RS18380	COG0642	Histidine kinase
EBA12_RS18400	COG2851	Citrate transporter
EBA12_RS18405	COG1028	Short-chain dehydrogenase reductase Sdr
EBA12_RS18415	COG1609	Transcriptional regulator
EBA12_RS18425	COG2211	Major facilitator Superfamily
EBA12_RS18455	COG0436	Aminotransferase
EBA12_RS18475	COG0726	polysaccharide deacetylase
EBA12_RS18480	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA12_RS18500	COG0402	S-adenosylhomocysteine deaminase activity
EBA12_RS18550	COG0242	peptide deformylase activity
EBA12_RS18555	COG3039	Transposase
EBA12_RS18590	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EBA12_RS18650	COG2188	Transcriptional regulator
EBA12_RS18665	COG1450	Type ii and iii secretion system protein
EBA12_RS18680	COG3166	PFAM Fimbrial assembly family protein
EBA12_RS18685	COG3156	type II secretion system protein K
EBA12_RS18690	COG4795	General secretion pathway protein
EBA12_RS18695	COG2165	general secretion pathway protein
EBA12_RS18700	COG4970	Tfp pilus assembly protein FimT
EBA12_RS18705	COG2165	general secretion pathway protein
EBA12_RS18710	COG1459	type II secretion system
EBA12_RS18720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA12_RS18725	COG1404	Belongs to the peptidase S8 family
EBA12_RS18730	COG5295	Hep Hag repeat protein
EBA12_RS18740	COG0047	phosphoribosylformylglycinamidine synthase activity
EBA12_RS18740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBA12_RS18750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EBA12_RS18755	COG4974	Belongs to the 'phage' integrase family
EBA12_RS18770	COG0795	lipopolysaccharide-transporting ATPase activity
EBA12_RS18780	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBA12_RS18805	COG0525	valine-tRNA ligase activity
EBA12_RS18835	COG2826	transposase and inactivated derivatives, IS30 family
EBA12_RS18845	COG2826	transposase and inactivated derivatives, IS30 family
EBA12_RS18870	COG1183	phosphatidylcholine synthase activity
EBA12_RS18880	COG0442	prolyl-tRNA aminoacylation
EBA12_RS18895	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA12_RS18900	COG1127	ABC transporter
EBA12_RS18905	COG3218	ABC-type transport auxiliary lipoprotein component
EBA12_RS18905	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA12_RS18950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBA12_RS18955	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EBA12_RS18955	COG0662	Cupin 2, conserved barrel domain protein
EBA12_RS18985	COG2086	electron transfer activity
EBA12_RS19055	COG0626	cystathionine gamma-synthase activity
EBA12_RS19085	COG0625	glutathione transferase activity
EBA12_RS19100	COG0513	Belongs to the DEAD box helicase family
EBA12_RS19110	COG0720	synthase
EBA12_RS19120	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EBA12_RS19125	COG1956	GAF domain-containing protein
EBA12_RS19135	COG0546	phosphoglycolate phosphatase activity
EBA12_RS19165	COG0339	signal peptide processing
EBA12_RS19215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA12_RS19280	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EBA12_RS19285	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EBA12_RS19290	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EBA12_RS19300	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EBA12_RS19310	COG0356	it plays a direct role in the translocation of protons across the membrane
EBA12_RS19330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EBA12_RS19340	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBA12_RS19375	COG2011	ABC-type metal ion transport system permease component
EBA12_RS19385	COG0697	spore germination
EBA12_RS19420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EBA12_RS19425	COG1187	pseudouridine synthase activity
EBA12_RS19430	COG2813	Specifically methylates the guanine in position
EBA12_RS19460	COG2202	Pas domain
EBA12_RS19460	COG2205	protein histidine kinase activity
EBA12_RS19485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA12_RS19535	COG0745	RESPONSE REGULATOR receiver
EBA12_RS19550	COG1404	Belongs to the peptidase S8 family
EBA12_RS19565	COG0842	Transport permease protein
EBA12_RS19570	COG1131	(ABC) transporter
EBA12_RS19575	COG0025	NhaP-type Na H and K H
EBA12_RS19585	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EBA12_RS19595	COG1573	uracil-dna glycosylase
EBA12_RS19605	COG3384	dioxygenase
EBA12_RS19630	COG3590	peptidase
EBA12_RS19650	COG0531	amino acid
EBA12_RS19675	COG3685	Protein conserved in bacteria
EBA12_RS19680	COG3546	catalase activity
EBA12_RS19705	COG3039	Transposase
EBA12_RS19735	COG1271	oxidase subunit
EBA12_RS19740	COG1294	oxidase, subunit
EBA12_RS19770	COG1063	alcohol dehydrogenase
EBA12_RS19865	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EBA12_RS19865	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EBA12_RS19875	COG1473	amidohydrolase
EBA12_RS19880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA12_RS19885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA12_RS19910	COG5383	Protein conserved in bacteria
EBA12_RS19965	COG3023	N-Acetylmuramoyl-L-alanine amidase
EBA12_RS19975	COG4948	Mandelate Racemase Muconate Lactonizing
EBA12_RS20005	COG0531	amino acid
EBA12_RS20025	COG4682	membrane
EBA12_RS20030	COG2133	pyrroloquinoline quinone binding
EBA12_RS20050	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EBA12_RS20055	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EBA12_RS20065	COG1610	YqeY-like protein
EBA12_RS20085	COG1295	ribonuclease BN
EBA12_RS20090	COG0358	DNA primase activity
EBA12_RS20155	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EBA12_RS20170	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EBA12_RS20235	COG0739	heme binding
EBA12_RS20250	COG2211	Major facilitator Superfamily
EBA12_RS20255	COG0708	Exodeoxyribonuclease III
EBA12_RS20270	COG1192	Involved in chromosome partitioning
EBA12_RS20275	COG1475	DNA binding
EBA12_RS20295	COG0463	Glycosyl transferase, family 2
EBA12_RS20320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EBA12_RS20345	COG4221	oxidoreductase activity
EBA12_RS20385	COG1166	arginine decarboxylase activity
EBA12_RS20390	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EBA12_RS20435	COG0606	chelatase, subunit chli
EBA12_RS20460	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EBA12_RS20480	COG3039	Transposase
EBA12_RS20540	COG1090	epimerase
EBA12_RS20550	COG0642	Histidine kinase
EBA12_RS20565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA12_RS20600	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBA12_RS20610	COG1595	DNA-templated transcription, initiation
EBA12_RS20615	COG0753	catalase activity
EBA12_RS20640	COG0697	spore germination
EBA12_RS20665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA12_RS20670	COG0180	Tryptophanyl-tRNA synthetase
EBA12_RS20675	COG3237	CsbD-like
EBA12_RS20690	COG0010	Belongs to the arginase family
EBA12_RS20710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EBA12_RS20725	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EBA12_RS20730	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EBA12_RS20730	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EBA12_RS20740	COG3228	Belongs to the MtfA family
EBA12_RS20770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA12_RS20825	COG3039	Transposase
EBA12_RS20830	COG1566	PFAM secretion protein HlyD family protein
EBA12_RS20845	COG1199	ATP-dependent helicase activity
EBA12_RS20890	COG0583	DNA-binding transcription factor activity
EBA12_RS20940	COG0625	glutathione transferase activity
EBA12_RS20950	COG2826	transposase and inactivated derivatives, IS30 family
EBA12_RS20980	COG4555	ABC transporter
EBA12_RS20990	COG1476	TRANSCRIPTIONal
EBA12_RS21010	COG1230	cation diffusion facilitator family transporter
EBA12_RS21015	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA12_RS21020	COG1131	(ABC) transporter
EBA12_RS21025	COG0842	Transport permease protein
EBA12_RS21035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EBA12_RS21070	COG2951	lytic endotransglycosylase activity
EBA12_RS21085	COG1196	nuclear chromosome segregation
EBA12_RS21090	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA12_RS21100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA12_RS21115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EBA12_RS21115	COG1042	CoA-binding domain protein
EBA12_RS21115	COG0045	succinate-CoA ligase (ADP-forming) activity
EBA12_RS21125	COG2239	Acts as a magnesium transporter
EBA12_RS21150	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA12_RS21155	COG3387	PFAM Glycoside hydrolase 15-related
EBA12_RS21170	COG3100	YcgL domain-containing protein
EBA12_RS21175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EBA12_RS21185	COG0463	Glycosyl transferase, family 2
EBA12_RS21195	COG1028	Short-chain dehydrogenase reductase Sdr
EBA12_RS21225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBA12_RS21240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBA12_RS21290	COG0408	coproporphyrinogen oxidase activity
EBA12_RS21370	COG0210	DNA helicase
EBA12_RS21390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA12_RS21405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EBA12_RS21420	COG2159	amidohydrolase
EBA12_RS21450	COG0357	Ribosomal RNA small subunit methyltransferase G
EBA12_RS21455	COG3540	Alkaline phosphatase
EBA12_RS21465	COG2091	lysine biosynthetic process via aminoadipic acid
EBA12_RS21480	COG0708	Exodeoxyribonuclease III
EBA12_RS21495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EBA12_RS21500	COG3162	membrane
EBA12_RS21555	COG1028	Short-chain dehydrogenase reductase Sdr
EBA12_RS21560	COG0179	Fumarylacetoacetate (FAA) hydrolase
EBA12_RS21570	COG4948	Mandelate Racemase Muconate Lactonizing
EBA12_RS21575	COG3254	rhamnose metabolic process
EBA12_RS21580	COG0738	Major facilitator superfamily
EBA12_RS21585	COG1414	Transcriptional regulator
EBA12_RS21595	COG2205	protein histidine kinase activity
EBA12_RS21605	COG3459	Glycosyltransferase 36 associated
EBA12_RS21610	COG2211	Major facilitator Superfamily
EBA12_RS21615	COG3265	gluconokinase activity
EBA12_RS21620	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA12_RS21650	COG3039	Transposase
EBA12_RS21660	COG3039	Transposase
EBA12_RS21665	COG2911	Protein conserved in bacteria
EBA12_RS21670	COG0729	surface antigen
EBA12_RS21675	COG4771	TonB-dependent receptor
EBA12_RS21680	COG0457	Tetratricopeptide repeat
EBA12_RS21695	COG0752	glycyl-tRNA synthetase alpha subunit
EBA12_RS21700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA12_RS21710	COG0519	Catalyzes the synthesis of GMP from XMP
EBA12_RS21710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA12_RS21720	COG0805	protein transport
EBA12_RS21725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA12_RS21730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA12_RS21740	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EBA12_RS21770	COG2974	May be involved in recombination
EBA12_RS21775	COG0037	tRNA processing
EBA12_RS21800	COG3661	Belongs to the glycosyl hydrolase 67 family
EBA12_RS21810	COG4948	Mandelate Racemase Muconate Lactonizing
EBA12_RS21820	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA12_RS21825	COG0246	Mannitol dehydrogenase
EBA12_RS21860	COG2826	transposase and inactivated derivatives, IS30 family
EBA12_RS21885	COG3693	PFAM glycoside hydrolase, family 10
EBA12_RS21910	COG2211	Major facilitator Superfamily
EBA12_RS21925	COG3039	Transposase
EBA12_RS21955	COG2937	Belongs to the GPAT DAPAT family
EBA12_RS21990	COG0284	orotidine-5'-phosphate decarboxylase activity
EBA12_RS21995	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EBA12_RS22000	COG3132	Protein of unknown function, DUF480
EBA12_RS22015	COG0210	DNA helicase
EBA12_RS22030	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EBA12_RS22040	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EBA12_RS22095	COG0676	glucose-6-phosphate 1-epimerase activity
EBA12_RS22110	COG0730	response to heat
EBA12_RS22145	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EBA12_RS22150	COG0302	gtp cyclohydrolase
EBA12_RS22180	COG2826	transposase and inactivated derivatives, IS30 family
EBA12_RS22190	COG0477	Major facilitator Superfamily
EBA12_RS22205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA12_RS22250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA12_RS22300	COG3237	CsbD-like
EBA12_RS22325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA12_RS22355	COG1304	FMN binding
EBA12_RS22380	COG4772	TonB-dependent receptor
EBA12_RS22390	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EBA12_RS22420	COG3039	Transposase
EBA12_RS22475	COG0564	pseudouridine synthase activity
EBA12_RS22490	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA12_RS22505	COG3039	Transposase
EBA12_RS22525	COG3039	Transposase
EBA12_RS22550	COG3039	Transposase
EBA12_RS22630	COG1074	ATP-dependent DNA helicase activity
EBA12_RS22635	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EBA12_RS22640	COG1116	anion transmembrane transporter activity
EBA12_RS22650	COG3039	Transposase
EBA12_RS22655	COG3039	Transposase
EBA12_RS22670	COG1136	(ABC) transporter
EBA12_RS22690	COG1127	ABC transporter
EBA12_RS22695	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA12_RS22700	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA12_RS22715	COG2853	Lipoprotein
EBA12_RS22745	COG0386	Belongs to the glutathione peroxidase family
EBA12_RS22755	COG1322	Protein conserved in bacteria
EBA12_RS22760	COG3039	Transposase
EBA12_RS22785	COG1929	Belongs to the glycerate kinase type-1 family
EBA12_RS22790	COG2271	Major facilitator Superfamily
EBA12_RS22805	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBA12_RS22815	COG0861	Integral membrane protein TerC family
EBA12_RS22825	COG0584	glycerophosphoryl diester phosphodiesterase
EBA12_RS22835	COG0671	phosphoesterase, PA-phosphatase related
EBA12_RS22840	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EBA12_RS22845	COG0726	polysaccharide deacetylase