locus-tag	class	description
NO430_RS00020	COG0187	DNA topoisomerase II activity
NO430_RS00030	COG0501	Belongs to the peptidase M48B family
NO430_RS00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NO430_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NO430_RS00135	COG0793	Belongs to the peptidase S41A family
NO430_RS00140	COG4942	peptidase
NO430_RS00150	COG2234	aminopeptidase activity
NO430_RS00160	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NO430_RS00175	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NO430_RS00180	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NO430_RS00185	COG1064	alcohol dehydrogenase
NO430_RS00210	COG0493	'glutamate synthase
NO430_RS00215	COG0067	glutamate synthase
NO430_RS00215	COG0069	glutamate synthase activity
NO430_RS00215	COG0070	glutamate synthase
NO430_RS00280	COG1205	dead DEAH box helicase
NO430_RS00280	COG1111	helicase
NO430_RS00285	COG1272	protein, Hemolysin III
NO430_RS00315	COG2032	superoxide dismutase activity
NO430_RS00320	COG2204	response regulator
NO430_RS00325	COG3852	Histidine kinase
NO430_RS00330	COG0004	ammonium transporteR
NO430_RS00335	COG0347	Belongs to the P(II) protein family
NO430_RS00340	COG0174	glutamine synthetase
NO430_RS00345	COG1968	undecaprenyl-diphosphatase activity
NO430_RS00390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NO430_RS00400	COG2062	phosphohistidine phosphatase, SixA
NO430_RS00405	COG0489	protein tyrosine kinase activity
NO430_RS00425	COG1396	sequence-specific DNA binding
NO430_RS00430	COG3550	peptidyl-serine autophosphorylation
NO430_RS00435	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
NO430_RS00440	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NO430_RS00455	COG1125	glycine betaine transport
NO430_RS00470	COG1119	ATPase activity
NO430_RS00480	COG1473	amidohydrolase
NO430_RS00500	COG1522	sequence-specific DNA binding
NO430_RS00505	COG3186	Phenylalanine-4-hydroxylase
NO430_RS00535	COG1609	Transcriptional regulator
NO430_RS00570	COG0366	Alpha amylase catalytic
NO430_RS00575	COG0366	Alpha amylase catalytic
NO430_RS00585	COG3039	Transposase
NO430_RS00635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NO430_RS00640	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NO430_RS00655	COG0028	Belongs to the TPP enzyme family
NO430_RS00660	COG4191	Histidine kinase
NO430_RS00685	COG3039	Transposase
NO430_RS00690	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NO430_RS00705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NO430_RS00710	COG3177	Filamentation induced by cAMP protein fic
NO430_RS00715	COG0596	Alpha beta hydrolase
NO430_RS00720	COG0727	PFAM Uncharacterised protein family (UPF0153)
NO430_RS00725	COG0318	PFAM AMP-dependent synthetase and ligase
NO430_RS00730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NO430_RS00745	COG1181	Belongs to the D-alanine--D-alanine ligase family
NO430_RS00755	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NO430_RS00770	COG0564	pseudouridine synthase activity
NO430_RS00795	COG0339	signal peptide processing
NO430_RS00840	COG4770	biotin carboxylase activity
NO430_RS00845	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NO430_RS00850	COG1960	acyl-CoA dehydrogenase activity
NO430_RS00905	COG0697	spore germination
NO430_RS00915	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NO430_RS00920	COG1846	Transcriptional regulator
NO430_RS00925	COG1764	response to oxidative stress
NO430_RS00975	COG0656	L-ascorbic acid biosynthetic process
NO430_RS00985	COG2130	NADP-dependent
NO430_RS01000	COG1187	pseudouridine synthase activity
NO430_RS01020	COG4807	Protein conserved in bacteria
NO430_RS01025	COG2351	hydroxyisourate hydrolase activity
NO430_RS01050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NO430_RS01055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NO430_RS01095	COG3039	Transposase
NO430_RS01125	COG0084	hydrolase, TatD family'
NO430_RS01140	COG0583	DNA-binding transcription factor activity
NO430_RS01145	COG2814	Major facilitator Superfamily
NO430_RS01155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NO430_RS01160	COG1902	pentaerythritol trinitrate reductase activity
NO430_RS01190	COG0745	RESPONSE REGULATOR receiver
NO430_RS01210	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NO430_RS01215	COG0583	DNA-binding transcription factor activity
NO430_RS01245	COG0702	epimerase
NO430_RS01250	COG1733	regulation of RNA biosynthetic process
NO430_RS01275	COG3039	Transposase
NO430_RS01300	COG0129	dihydroxy-acid dehydratase activity
NO430_RS01310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NO430_RS01385	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NO430_RS01390	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NO430_RS01400	COG3485	protocatechuate 3,4-dioxygenase
NO430_RS01405	COG3485	protocatechuate 3,4-dioxygenase
NO430_RS01420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NO430_RS01425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NO430_RS01440	COG1414	Transcriptional regulator
NO430_RS01480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NO430_RS01520	COG0156	8-amino-7-oxononanoate synthase activity
NO430_RS01525	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NO430_RS01530	COG1040	competence protein
NO430_RS01535	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NO430_RS01640	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NO430_RS01710	COG1511	domain protein
NO430_RS01710	COG3264	Mechanosensitive ion channel
NO430_RS01720	COG3039	Transposase
NO430_RS01725	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NO430_RS01730	COG2354	Protein conserved in bacteria
NO430_RS01755	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NO430_RS01780	COG0702	epimerase
NO430_RS01790	COG1028	Short-chain dehydrogenase reductase Sdr
NO430_RS01825	COG0513	Belongs to the DEAD box helicase family
NO430_RS01830	COG3039	Transposase
NO430_RS01855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NO430_RS01865	COG3483	tryptophan 2,3-dioxygenase activity
NO430_RS01870	COG3104	oligopeptide transport
NO430_RS01890	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NO430_RS01900	COG1320	monovalent cation:proton antiporter activity
NO430_RS01905	COG2212	antiporter activity
NO430_RS01915	COG0651	ATP synthesis coupled electron transport
NO430_RS01920	COG1006	Multisubunit Na H antiporter MnhC subunit
NO430_RS01925	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NO430_RS01925	COG2111	Na H antiporter
NO430_RS01955	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NO430_RS01965	COG0456	acetyltransferase
NO430_RS02000	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NO430_RS02005	COG0134	indole-3-glycerol-phosphate synthase activity
NO430_RS02015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NO430_RS02020	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NO430_RS02030	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
NO430_RS02035	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NO430_RS02040	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NO430_RS02110	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NO430_RS02125	COG2814	Major facilitator Superfamily
NO430_RS02135	COG2814	Major facilitator Superfamily
NO430_RS02140	COG1289	transmembrane transporter activity
NO430_RS02150	COG0151	Belongs to the GarS family
NO430_RS02160	COG0138	bifunctional purine biosynthesis protein purh
NO430_RS02165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NO430_RS02175	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NO430_RS02220	COG0439	Biotin carboxylase
NO430_RS02230	COG0511	ligase activity, forming carbon-carbon bonds
NO430_RS02235	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NO430_RS02245	COG1324	tolerance protein
NO430_RS02265	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NO430_RS02285	COG0534	Mate efflux family protein
NO430_RS02290	COG0616	signal peptide processing
NO430_RS02300	COG1028	Short-chain dehydrogenase reductase Sdr
NO430_RS02315	COG0009	L-threonylcarbamoyladenylate synthase
NO430_RS02320	COG1754	DNA topoisomerase type I activity
NO430_RS02320	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NO430_RS02340	COG0758	DNA mediated transformation
NO430_RS02345	COG1652	LysM domain
NO430_RS02350	COG0242	peptide deformylase activity
NO430_RS02355	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NO430_RS02360	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NO430_RS02360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NO430_RS02410	COG1560	Kdo2-lipid A biosynthetic process
NO430_RS02420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NO430_RS02450	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NO430_RS02455	COG3118	belongs to the thioredoxin family
NO430_RS02465	COG2884	Cell division ATP-binding protein ftsE
NO430_RS02470	COG2177	Part of the ABC transporter FtsEX involved in
NO430_RS02475	COG2201	protein-glutamate methylesterase activity
NO430_RS02480	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NO430_RS02485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NO430_RS02490	COG2860	membrane
NO430_RS02495	COG1252	NADH dehydrogenase
NO430_RS02515	COG0459	protein refolding
NO430_RS02530	COG3039	Transposase
NO430_RS02540	COG3039	Transposase
NO430_RS02550	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NO430_RS02565	COG3386	PFAM SMP-30 Gluconolaconase
NO430_RS02580	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NO430_RS02625	COG2353	YceI-like domain
NO430_RS02695	COG2801	Transposase and inactivated derivatives
NO430_RS02745	COG4221	oxidoreductase activity
NO430_RS02800	COG0697	spore germination
NO430_RS02805	COG4305	rare lipoprotein A
NO430_RS02810	COG5297	Belongs to the glycosyl hydrolase family 6
NO430_RS02820	COG1113	amino acid transport
NO430_RS02830	COG0598	Magnesium transport protein CorA
NO430_RS02900	COG5001	Diguanylate cyclase
NO430_RS02900	COG3300	MHYT domain
NO430_RS02920	COG5297	Belongs to the glycosyl hydrolase family 6
NO430_RS02920	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NO430_RS02925	COG0659	secondary active sulfate transmembrane transporter activity
NO430_RS02955	COG3275	phosphorelay sensor kinase activity
NO430_RS02965	COG0181	hydroxymethylbilane synthase activity
NO430_RS02990	COG1505	serine-type exopeptidase activity
NO430_RS02995	COG0436	Aminotransferase
NO430_RS03005	COG2832	Protein of unknown function (DUF454)
NO430_RS03025	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NO430_RS03035	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NO430_RS03070	COG5001	Diguanylate cyclase
NO430_RS03070	COG3300	MHYT domain
NO430_RS03075	COG0308	aminopeptidase N
NO430_RS03090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NO430_RS03095	COG1077	Cell shape determining protein MreB Mrl
NO430_RS03100	COG1792	Involved in formation and maintenance of cell shape
NO430_RS03115	COG0772	Belongs to the SEDS family
NO430_RS03135	COG2951	lytic endotransglycosylase activity
NO430_RS03140	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NO430_RS03145	COG1686	Belongs to the peptidase S11 family
NO430_RS03160	COG2921	Belongs to the UPF0250 family
NO430_RS03185	COG1051	belongs to the nudix hydrolase family
NO430_RS03185	COG1056	cytidyltransferase-related domain
NO430_RS03220	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NO430_RS03225	COG0673	inositol 2-dehydrogenase activity
NO430_RS03230	COG2823	Periplasmic or secreted lipoprotein
NO430_RS03235	COG4251	negative regulation of phosphorylation
NO430_RS03240	COG0784	Response regulator, receiver
NO430_RS03245	COG4191	Histidine kinase
NO430_RS03250	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NO430_RS03275	COG3039	Transposase
NO430_RS03290	COG3250	beta-galactosidase activity
NO430_RS03305	COG2188	Transcriptional regulator
NO430_RS03315	COG1609	Transcriptional regulator
NO430_RS03320	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NO430_RS03325	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NO430_RS03340	COG1215	transferase activity, transferring glycosyl groups
NO430_RS03345	COG0726	polysaccharide deacetylase
NO430_RS03345	COG1649	PFAM Uncharacterised BCR, COG1649
NO430_RS03370	COG3039	Transposase
NO430_RS03380	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NO430_RS03425	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NO430_RS03465	COG2205	protein histidine kinase activity
NO430_RS03495	COG3791	Glutathione-dependent formaldehyde-activating
NO430_RS03510	COG3039	Transposase
NO430_RS03525	COG0488	(ABC) transporter
NO430_RS03545	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NO430_RS03555	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NO430_RS03565	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NO430_RS03565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NO430_RS03585	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NO430_RS03590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NO430_RS03595	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NO430_RS03620	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NO430_RS03625	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NO430_RS03635	COG2205	protein histidine kinase activity
NO430_RS03640	COG0745	RESPONSE REGULATOR receiver
NO430_RS03670	COG0277	FAD linked oxidase domain protein
NO430_RS03680	COG0792	nuclease activity
NO430_RS03725	COG0275	rRNA processing
NO430_RS03730	COG3116	cell division
NO430_RS03745	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NO430_RS03750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NO430_RS03765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NO430_RS03770	COG1181	Belongs to the D-alanine--D-alanine ligase family
NO430_RS03775	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NO430_RS03790	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NO430_RS03800	COG0739	heme binding
NO430_RS03800	COG0741	lytic transglycosylase activity
NO430_RS03800	COG1196	nuclear chromosome segregation
NO430_RS03815	COG0494	nUDIX hydrolase
NO430_RS03830	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NO430_RS03840	COG1028	Short-chain dehydrogenase reductase Sdr
NO430_RS03840	COG3321	synthase
NO430_RS03840	COG0604	alcohol dehydrogenase
NO430_RS03890	COG2226	methyltransferase
NO430_RS03895	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NO430_RS03920	COG2826	transposase and inactivated derivatives, IS30 family
NO430_RS03940	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NO430_RS03955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NO430_RS03965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NO430_RS03970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NO430_RS03980	COG0667	Aldo Keto reductase
NO430_RS04005	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NO430_RS04015	COG2175	clavaminate synthase activity
NO430_RS04025	COG4181	ATPase activity
NO430_RS04040	COG0642	Histidine kinase
NO430_RS04055	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NO430_RS04075	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NO430_RS04095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NO430_RS04100	COG2967	ApaG domain
NO430_RS04105	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NO430_RS04120	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NO430_RS04135	COG0123	including yeast histone deacetylase and acetoin utilization protein
NO430_RS04140	COG2096	Adenosyltransferase
NO430_RS04160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NO430_RS04180	COG1802	Transcriptional regulator
NO430_RS04190	COG3384	dioxygenase
NO430_RS04195	COG0583	DNA-binding transcription factor activity
NO430_RS04200	COG0318	PFAM AMP-dependent synthetase and ligase
NO430_RS04210	COG1024	Enoyl-CoA hydratase
NO430_RS04230	COG3386	PFAM SMP-30 Gluconolaconase
NO430_RS04280	COG2197	response regulator
NO430_RS04290	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NO430_RS04295	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NO430_RS04300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NO430_RS04305	COG0583	DNA-binding transcription factor activity
NO430_RS04310	COG3634	alkyl hydroperoxide reductase activity
NO430_RS04320	COG2890	protein-(glutamine-N5) methyltransferase activity
NO430_RS04355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NO430_RS04355	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NO430_RS04370	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NO430_RS04420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NO430_RS04430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NO430_RS04460	COG1295	ribonuclease BN
NO430_RS04465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NO430_RS04470	COG1254	Belongs to the acylphosphatase family
NO430_RS04485	COG0521	Mo-molybdopterin cofactor biosynthetic process
NO430_RS04495	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NO430_RS04500	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NO430_RS04510	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NO430_RS04525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NO430_RS04535	COG0193	aminoacyl-tRNA hydrolase activity
NO430_RS04540	COG0012	GTP binding
NO430_RS04575	COG0250	Participates in transcription elongation, termination and antitermination
NO430_RS04580	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NO430_RS04585	COG0081	regulation of translation
NO430_RS04590	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NO430_RS04600	COG0085	RNA polymerase activity
NO430_RS04605	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NO430_RS04610	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NO430_RS04615	COG0049	tRNA binding
NO430_RS04645	COG0088	Forms part of the polypeptide exit tunnel
NO430_RS04650	COG0089	rRNA binding
NO430_RS04655	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NO430_RS04665	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NO430_RS04675	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NO430_RS04680	COG0255	Belongs to the universal ribosomal protein uL29 family
NO430_RS04685	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NO430_RS04690	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NO430_RS04695	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NO430_RS04730	COG1841	ribosomal large subunit assembly
NO430_RS04735	COG0200	Binds to the 23S rRNA
NO430_RS04740	COG0201	protein transport
NO430_RS04750	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NO430_RS04755	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NO430_RS04765	COG0203	ribosomal protein L17
NO430_RS04780	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NO430_RS04800	COG1217	gtp-binding protein TYPA
NO430_RS04805	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NO430_RS04815	COG0625	glutathione transferase activity
NO430_RS04825	COG0584	glycerophosphoryl diester phosphodiesterase
NO430_RS04840	COG3039	Transposase
NO430_RS04865	COG1902	pentaerythritol trinitrate reductase activity
NO430_RS04865	COG0446	pyridine nucleotide-disulphide oxidoreductase
NO430_RS04870	COG0604	alcohol dehydrogenase
NO430_RS04895	COG0156	8-amino-7-oxononanoate synthase activity
NO430_RS04900	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NO430_RS04905	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NO430_RS04910	COG4208	sulfate ABC transporter
NO430_RS04915	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NO430_RS04950	COG0406	alpha-ribazole phosphatase activity
NO430_RS04960	COG0285	dihydrofolate synthase activity
NO430_RS04980	COG2833	Protein of unknown function (DUF455)
NO430_RS05005	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NO430_RS05010	COG0671	phosphoesterase, PA-phosphatase related
NO430_RS05015	COG0438	transferase activity, transferring glycosyl groups
NO430_RS05025	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NO430_RS05030	COG5002	protein histidine kinase activity
NO430_RS05040	COG4783	chaperone-mediated protein folding
NO430_RS05055	COG0473	3-isopropylmalate dehydrogenase activity
NO430_RS05095	COG3039	Transposase
NO430_RS05120	COG0544	peptidyl-prolyl cis-trans isomerase activity
NO430_RS05160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NO430_RS05185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NO430_RS05200	COG0631	protein serine/threonine phosphatase activity
NO430_RS05220	COG3039	Transposase
NO430_RS05230	COG0859	PFAM glycosyl transferase family 9
NO430_RS05235	COG3642	lipopolysaccharide core region biosynthetic process
NO430_RS05240	COG1234	tRNA 3'-trailer cleavage
NO430_RS05245	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NO430_RS05255	COG0315	cyclic pyranopterin monophosphate synthase activity
NO430_RS05260	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NO430_RS05265	COG0314	molybdopterin synthase activity
NO430_RS05300	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NO430_RS05310	COG0537	adenosine 5'-monophosphoramidase activity
NO430_RS05330	COG0714	Associated with various cellular activities
NO430_RS05350	COG1399	metal-binding, possibly nucleic acid-binding protein
NO430_RS05375	COG1028	Short-chain dehydrogenase reductase Sdr
NO430_RS05380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO430_RS05390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NO430_RS05395	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NO430_RS05430	COG3829	transcription factor binding
NO430_RS05460	COG3039	Transposase
NO430_RS05535	COG0330	HflC and HflK could
NO430_RS05540	COG0330	HflC and HflK could
NO430_RS05550	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NO430_RS05555	COG0308	aminopeptidase N
NO430_RS05570	COG0732	type I restriction modification DNA specificity domain
NO430_RS05585	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
NO430_RS05665	COG0587	DNA-directed DNA polymerase activity
NO430_RS05680	COG1297	OPT oligopeptide transporter protein
NO430_RS05695	COG0823	Involved in the tonB-independent uptake of proteins
NO430_RS05695	COG1506	peptidase
NO430_RS05705	COG1917	Cupin 2, conserved barrel domain protein
NO430_RS05705	COG2207	Transcriptional regulator
NO430_RS05745	COG0753	catalase activity
NO430_RS05780	COG3551	Protein conserved in bacteria
NO430_RS05810	COG2194	sulfuric ester hydrolase activity
NO430_RS05820	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NO430_RS05825	COG0745	RESPONSE REGULATOR receiver
NO430_RS05830	COG0642	Histidine kinase
NO430_RS05840	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NO430_RS05845	COG2894	cell division
NO430_RS05860	COG4585	Histidine kinase
NO430_RS05865	COG2197	response regulator
NO430_RS05880	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NO430_RS05905	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NO430_RS05980	COG2826	transposase and inactivated derivatives, IS30 family
NO430_RS06000	COG3039	Transposase
NO430_RS06025	COG3179	chitinase
NO430_RS06175	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NO430_RS06190	COG1842	Phage shock protein A
NO430_RS06215	COG0754	glutathionylspermidine amidase activity
NO430_RS06275	COG0531	amino acid
NO430_RS06280	COG2197	response regulator
NO430_RS06285	COG2267	carboxylic ester hydrolase activity
NO430_RS06295	COG1113	amino acid transport
NO430_RS06325	COG3039	Transposase
NO430_RS06335	COG1294	oxidase, subunit
NO430_RS06345	COG2239	Acts as a magnesium transporter
NO430_RS06350	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NO430_RS06355	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NO430_RS06365	COG3039	Transposase
NO430_RS06380	COG1660	Displays ATPase and GTPase activities
NO430_RS06390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NO430_RS06405	COG1137	ATPase activity
NO430_RS06410	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NO430_RS06420	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NO430_RS06430	COG0271	Belongs to the BolA IbaG family
NO430_RS06435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NO430_RS06455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NO430_RS06470	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NO430_RS06480	COG0628	permease
NO430_RS06490	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NO430_RS06495	COG3178	'Phosphotransferase
NO430_RS06505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NO430_RS06510	COG1555	photosystem II stabilization
NO430_RS06525	COG3039	Transposase
NO430_RS06530	COG2146	nitrite reductase [NAD(P)H] activity
NO430_RS06540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NO430_RS06545	COG0719	Fe-S assembly protein
NO430_RS06550	COG0396	ATPase activity
NO430_RS06555	COG0719	Fe-S assembly protein
NO430_RS06560	COG1959	2 iron, 2 sulfur cluster binding
NO430_RS06615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NO430_RS06650	COG0519	Catalyzes the synthesis of GMP from XMP
NO430_RS06660	COG1678	Uncharacterized ACR, COG1678
NO430_RS06665	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NO430_RS06680	COG1764	response to oxidative stress
NO430_RS06690	COG0384	phenazine biosynthesis protein PhzF
NO430_RS06700	COG0527	aspartate kinase activity
NO430_RS06725	COG3039	Transposase
NO430_RS06730	COG0142	geranyltranstransferase activity
NO430_RS06735	COG0629	single-stranded DNA binding
NO430_RS06740	COG2203	Gaf domain
NO430_RS06740	COG3706	GGDEF domain
NO430_RS06740	COG4251	negative regulation of phosphorylation
NO430_RS06740	COG5001	Diguanylate cyclase
NO430_RS06790	COG2879	small protein
NO430_RS06795	COG1966	Carbon starvation protein
NO430_RS06800	COG1741	Belongs to the pirin family
NO430_RS06890	COG1515	deoxyribonuclease V activity
NO430_RS06910	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NO430_RS06915	COG2202	Pas domain
NO430_RS06915	COG2200	EAL domain
NO430_RS06915	COG2199	diguanylate cyclase activity
NO430_RS06920	COG0835	chemotaxis
NO430_RS06925	COG0840	transmembrane signaling receptor activity
NO430_RS06930	COG0643	Histidine kinase
NO430_RS06930	COG2198	Histidine kinase
NO430_RS06945	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NO430_RS06955	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NO430_RS07000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NO430_RS07005	COG0735	belongs to the Fur family
NO430_RS07035	COG2826	transposase and inactivated derivatives, IS30 family
NO430_RS07130	COG3039	Transposase
NO430_RS07185	COG5001	Diguanylate cyclase
NO430_RS07185	COG5002	protein histidine kinase activity
NO430_RS07190	COG1187	pseudouridine synthase activity
NO430_RS07210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NO430_RS07220	COG0475	glutathione-regulated potassium exporter activity
NO430_RS07225	COG5000	phosphorelay sensor kinase activity
NO430_RS07225	COG5002	protein histidine kinase activity
NO430_RS07230	COG0745	RESPONSE REGULATOR receiver
NO430_RS07235	COG1538	Outer membrane efflux protein
NO430_RS07260	COG1132	(ABC) transporter
NO430_RS07285	COG3039	Transposase
NO430_RS07325	COG3118	belongs to the thioredoxin family
NO430_RS07350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NO430_RS07375	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NO430_RS07400	COG2968	Membrane
NO430_RS07415	COG3164	Protein of unknown function
NO430_RS07425	COG0312	modulator of DNA gyrase
NO430_RS07430	COG3028	Belongs to the UPF0307 family
NO430_RS07435	COG0312	modulator of DNA gyrase
NO430_RS07450	COG4104	PAAR repeat-containing protein
NO430_RS07460	COG0142	geranyltranstransferase activity
NO430_RS07465	COG1722	exodeoxyribonuclease VII activity
NO430_RS07470	COG0037	tRNA processing
NO430_RS07475	COG1785	Belongs to the alkaline phosphatase family
NO430_RS07480	COG1301	dicarboxylic acid transport
NO430_RS07485	COG4106	trans-aconitate 2-methyltransferase activity
NO430_RS07500	COG0791	NLP P60 protein
NO430_RS07505	COG0791	NLP P60 protein
NO430_RS07510	COG1047	Peptidyl-prolyl cis-trans
NO430_RS07515	COG2311	Membrane
NO430_RS07520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO430_RS07545	COG3039	Transposase
NO430_RS07555	COG2826	transposase and inactivated derivatives, IS30 family
NO430_RS07580	COG2826	transposase and inactivated derivatives, IS30 family
NO430_RS07585	COG3039	Transposase
NO430_RS07595	COG0489	protein tyrosine kinase activity
NO430_RS07600	COG0717	Belongs to the dCTP deaminase family
NO430_RS07610	COG3039	Transposase
NO430_RS07630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NO430_RS07635	COG3039	Transposase
NO430_RS07645	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NO430_RS07660	COG2826	transposase and inactivated derivatives, IS30 family
NO430_RS07670	COG0433	COG0433 Predicted ATPase
NO430_RS07695	COG2890	protein-(glutamine-N5) methyltransferase activity
NO430_RS07700	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NO430_RS07705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NO430_RS07710	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NO430_RS07730	COG0101	tRNA pseudouridine synthase activity
NO430_RS07735	COG0135	phosphoribosylanthranilate isomerase activity
NO430_RS07745	COG0133	tryptophan synthase activity
NO430_RS07760	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NO430_RS07765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NO430_RS07820	COG0149	triose-phosphate isomerase activity
NO430_RS07835	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NO430_RS07845	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NO430_RS07850	COG0649	NAD binding
NO430_RS07855	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NO430_RS07860	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NO430_RS07865	COG1034	ATP synthesis coupled electron transport
NO430_RS07870	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NO430_RS07875	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NO430_RS07900	COG1007	ATP synthesis coupled electron transport
NO430_RS07910	COG0779	Required for maturation of 30S ribosomal subunits
NO430_RS07915	COG0195	Participates in both transcription termination and antitermination
NO430_RS07920	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NO430_RS07935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NO430_RS07940	COG1185	polyribonucleotide nucleotidyltransferase activity
NO430_RS07975	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NO430_RS07985	COG2095	MarC family integral membrane protein
NO430_RS08000	COG3039	Transposase
NO430_RS08005	COG1611	Belongs to the LOG family
NO430_RS08045	COG4969	Belongs to the N-Me-Phe pilin family
NO430_RS08050	COG0556	nucleotide-excision repair
NO430_RS08085	COG3723	Recombinational DNA repair protein, rece pathway
NO430_RS08190	COG0270	DNA (cytosine-5-)-methyltransferase activity
NO430_RS08410	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NO430_RS08420	COG2986	histidine ammonia-lyase
NO430_RS08425	COG1228	amidohydrolase
NO430_RS08465	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NO430_RS08470	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NO430_RS08475	COG1605	Chorismate mutase
NO430_RS08475	COG0077	Prephenate dehydratase
NO430_RS08480	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NO430_RS08505	COG3039	Transposase
NO430_RS08515	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NO430_RS08530	COG0583	DNA-binding transcription factor activity
NO430_RS08545	COG2336	PFAM SpoVT AbrB
NO430_RS08580	COG0840	transmembrane signaling receptor activity
NO430_RS08605	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NO430_RS08610	COG0784	Response regulator, receiver
NO430_RS08610	COG4191	Histidine kinase
NO430_RS08625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NO430_RS08645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NO430_RS08660	COG1595	DNA-templated transcription, initiation
NO430_RS08710	COG2244	polysaccharide biosynthetic process
NO430_RS08740	COG2264	protein methyltransferase activity
NO430_RS08750	COG0438	transferase activity, transferring glycosyl groups
NO430_RS08765	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NO430_RS08770	COG1132	(ABC) transporter
NO430_RS08780	COG0477	Major facilitator Superfamily
NO430_RS08790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NO430_RS08805	COG1253	flavin adenine dinucleotide binding
NO430_RS08815	COG0306	phosphate transporter
NO430_RS08840	COG0504	CTP synthase activity
NO430_RS08845	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NO430_RS08855	COG0148	phosphopyruvate hydratase activity
NO430_RS08860	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NO430_RS08875	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NO430_RS08885	COG2840	Smr protein MutS2
NO430_RS08890	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NO430_RS08895	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NO430_RS08900	COG1238	metal cluster binding
NO430_RS08915	COG1534	Rna-binding protein
NO430_RS08920	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NO430_RS08930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NO430_RS08945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NO430_RS08950	COG1546	Belongs to the CinA family
NO430_RS08965	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NO430_RS08970	COG2137	regulation of response to DNA damage stimulus
NO430_RS08975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NO430_RS08980	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NO430_RS09030	COG1741	Belongs to the pirin family
NO430_RS09035	COG0583	DNA-binding transcription factor activity
NO430_RS09060	COG0351	phosphomethylpyrimidine kinase
NO430_RS09060	COG0352	thiamine-phosphate diphosphorylase activity
NO430_RS09070	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NO430_RS09075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NO430_RS09090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NO430_RS09100	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NO430_RS09105	COG3734	2-keto-3-deoxy-galactonokinase
NO430_RS09115	COG4948	Mandelate Racemase Muconate Lactonizing
NO430_RS09120	COG0800	Aldolase
NO430_RS09145	COG1070	Carbohydrate kinase
NO430_RS09155	COG0477	Major facilitator Superfamily
NO430_RS09170	COG2801	Transposase and inactivated derivatives
NO430_RS09175	COG0860	N-Acetylmuramoyl-L-alanine amidase
NO430_RS09180	COG1469	GTP cyclohydrolase I activity
NO430_RS09190	COG0617	tRNA 3'-terminal CCA addition
NO430_RS09210	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NO430_RS09235	COG1472	Belongs to the glycosyl hydrolase 3 family
NO430_RS09250	COG2203	Gaf domain
NO430_RS09250	COG3706	GGDEF domain
NO430_RS09250	COG4251	negative regulation of phosphorylation
NO430_RS09250	COG5001	Diguanylate cyclase
NO430_RS09260	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NO430_RS09265	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NO430_RS09280	COG0671	phosphoesterase, PA-phosphatase related
NO430_RS09305	COG0697	spore germination
NO430_RS09310	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NO430_RS09335	COG1012	belongs to the aldehyde dehydrogenase family
NO430_RS09390	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NO430_RS09405	COG0124	histidyl-tRNA synthetase
NO430_RS09425	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NO430_RS09440	COG0131	Imidazoleglycerol-phosphate dehydratase
NO430_RS09440	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NO430_RS09450	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NO430_RS09460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NO430_RS09460	COG0140	phosphoribosyl-ATP diphosphatase activity
NO430_RS09480	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NO430_RS09485	COG0235	Class ii aldolase
NO430_RS09490	COG0531	amino acid
NO430_RS09495	COG0531	amino acid
NO430_RS09505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NO430_RS09510	COG0277	FAD linked oxidase domain protein
NO430_RS09530	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NO430_RS09585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NO430_RS09590	COG2258	MOSC domain
NO430_RS09595	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NO430_RS09600	COG0505	Belongs to the CarA family
NO430_RS09610	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NO430_RS09615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NO430_RS09625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NO430_RS09640	COG3279	Response regulator of the LytR AlgR family
NO430_RS09660	COG2198	Histidine kinase
NO430_RS09660	COG0784	Response regulator, receiver
NO430_RS09660	COG2205	protein histidine kinase activity
NO430_RS09665	COG1024	Enoyl-CoA hydratase
NO430_RS09670	COG0318	PFAM AMP-dependent synthetase and ligase
NO430_RS09700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NO430_RS09730	COG0840	transmembrane signaling receptor activity
NO430_RS09740	COG0835	chemotaxis
NO430_RS09755	COG0840	transmembrane signaling receptor activity
NO430_RS09760	COG0840	transmembrane signaling receptor activity
NO430_RS09765	COG0840	transmembrane signaling receptor activity
NO430_RS09780	COG0840	transmembrane signaling receptor activity
NO430_RS09790	COG0840	transmembrane signaling receptor activity
NO430_RS09795	COG0840	transmembrane signaling receptor activity
NO430_RS09820	COG0840	transmembrane signaling receptor activity
NO430_RS09825	COG2826	transposase and inactivated derivatives, IS30 family
NO430_RS09855	COG0745	RESPONSE REGULATOR receiver
NO430_RS09865	COG0835	chemotaxis
NO430_RS09870	COG1192	Involved in chromosome partitioning
NO430_RS09875	COG1360	Flagellar Motor Protein
NO430_RS09880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NO430_RS09890	COG4774	siderophore transport
NO430_RS09895	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NO430_RS09930	COG3039	Transposase
NO430_RS09995	COG0784	Response regulator, receiver
NO430_RS09995	COG2198	Histidine kinase
NO430_RS09995	COG0643	Histidine kinase
NO430_RS10050	COG1684	flagellar biosynthetic protein fliR
NO430_RS10065	COG3190	flagellar
NO430_RS10115	COG1677	Flagellar hook-basal body complex protein FliE
NO430_RS10145	COG1028	Short-chain dehydrogenase reductase Sdr
NO430_RS10155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NO430_RS10175	COG2201	protein-glutamate methylesterase activity
NO430_RS10205	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NO430_RS10210	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NO430_RS10225	COG1705	Flagellar rod assembly protein muramidase FlgJ
NO430_RS10225	COG3951	Flagellar rod assembly protein muramidase FlgJ
NO430_RS10230	COG1706	bacterial-type flagellum-dependent cell motility
NO430_RS10235	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NO430_RS10245	COG4787	bacterial-type flagellum-dependent cell motility
NO430_RS10255	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NO430_RS10260	COG1558	bacterial-type flagellum-dependent cell motility
NO430_RS10270	COG0784	Response regulator, receiver
NO430_RS10270	COG0835	chemotaxis
NO430_RS10290	COG5002	protein histidine kinase activity
NO430_RS10300	COG4585	Histidine kinase
NO430_RS10335	COG0482	sulfurtransferase activity
NO430_RS10350	COG0542	response to heat
NO430_RS10380	COG0492	ferredoxin-NADP+ reductase activity
NO430_RS10385	COG1674	ftsk spoiiie
NO430_RS10405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NO430_RS10425	COG0038	chloride channel
NO430_RS10435	COG0183	Belongs to the thiolase family
NO430_RS10440	COG1024	Enoyl-CoA hydratase
NO430_RS10440	COG1250	3-hydroxyacyl-CoA dehydrogenase
NO430_RS10455	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NO430_RS10475	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NO430_RS10480	COG1160	GTP binding
NO430_RS10485	COG0303	'Molybdopterin
NO430_RS10495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NO430_RS10530	COG0746	molybdenum cofactor guanylyltransferase activity
NO430_RS10550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NO430_RS10550	COG1648	precorrin-2 dehydrogenase activity
NO430_RS10580	COG3039	Transposase
NO430_RS10605	COG5001	Diguanylate cyclase
NO430_RS10625	COG4566	intracellular signal transduction
NO430_RS10715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NO430_RS10750	COG1024	Enoyl-CoA hydratase
NO430_RS10755	COG1024	Enoyl-CoA hydratase
NO430_RS10765	COG1024	Enoyl-CoA hydratase
NO430_RS10780	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NO430_RS10880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NO430_RS10885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NO430_RS10935	COG1858	cytochrome C peroxidase
NO430_RS10965	COG0515	serine threonine protein kinase
NO430_RS10970	COG0631	protein serine/threonine phosphatase activity
NO430_RS11030	COG2826	transposase and inactivated derivatives, IS30 family
NO430_RS11040	COG3039	Transposase
NO430_RS11120	COG3039	Transposase
NO430_RS11135	COG2154	pterin-4-alpha-carbinolamine dehydratase
NO430_RS11150	COG3064	Membrane
NO430_RS11160	COG1530	ribonuclease E activity
NO430_RS11170	COG1054	Belongs to the UPF0176 family
NO430_RS11190	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NO430_RS11230	COG0322	excinuclease ABC activity
NO430_RS11240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NO430_RS11250	COG1663	tetraacyldisaccharide 4'-kinase activity
NO430_RS11265	COG0811	peptide transport
NO430_RS11285	COG4591	ABC-type transport system involved in lipoprotein release permease component
NO430_RS11300	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NO430_RS11315	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NO430_RS11330	COG0354	folic acid binding
NO430_RS11345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NO430_RS11355	COG0363	glucosamine-6-phosphate deaminase activity
NO430_RS11360	COG0129	dihydroxy-acid dehydratase activity
NO430_RS11365	COG0800	Aldolase
NO430_RS11435	COG0784	Response regulator, receiver
NO430_RS11435	COG2205	protein histidine kinase activity
NO430_RS11445	COG2183	response to ionizing radiation
NO430_RS11455	COG0723	plastoquinol--plastocyanin reductase activity
NO430_RS11455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO430_RS11470	COG3243	poly(R)-hydroxyalkanoic acid synthase
NO430_RS11480	COG1183	phosphatidylcholine synthase activity
NO430_RS11485	COG1028	Short-chain dehydrogenase reductase Sdr
NO430_RS11500	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NO430_RS11510	COG0668	transmembrane transport
NO430_RS11530	COG1914	H( )-stimulated, divalent metal cation uptake system
NO430_RS11550	COG0583	DNA-binding transcription factor activity
NO430_RS11570	COG0583	DNA-binding transcription factor activity
NO430_RS11575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NO430_RS11580	COG3002	Belongs to the UPF0753 family
NO430_RS11585	COG0519	Catalyzes the synthesis of GMP from XMP
NO430_RS11585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NO430_RS11595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NO430_RS11620	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NO430_RS11630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NO430_RS11635	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NO430_RS11645	COG0776	regulation of translation
NO430_RS11650	COG0539	negative regulation of cytoplasmic translation
NO430_RS11655	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NO430_RS11670	COG2957	Belongs to the agmatine deiminase family
NO430_RS11680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NO430_RS11705	COG0395	ABC-type sugar transport system, permease component
NO430_RS11710	COG1175	transmembrane transport
NO430_RS11740	COG2350	Protein conserved in bacteria
NO430_RS11745	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NO430_RS11750	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NO430_RS11755	COG1187	pseudouridine synthase activity
NO430_RS11775	COG0436	Aminotransferase
NO430_RS11780	COG4133	protoheme IX ABC transporter activity
NO430_RS11830	COG1278	Cold shock
NO430_RS11840	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NO430_RS11845	COG4988	ABC transporter
NO430_RS11900	COG0165	Argininosuccinate lyase
NO430_RS11915	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NO430_RS11920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NO430_RS11925	COG0137	argininosuccinate synthase activity
NO430_RS11930	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NO430_RS11945	COG2166	iron-sulfur cluster assembly
NO430_RS11980	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NO430_RS11990	COG4302	ethanolamine ammonia-lyase activity
NO430_RS12005	COG4677	pectinesterase activity
NO430_RS12030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NO430_RS12035	COG0402	S-adenosylhomocysteine deaminase activity
NO430_RS12055	COG1509	lysine 2,3-aminomutase activity
NO430_RS12060	COG5001	Diguanylate cyclase
NO430_RS12060	COG3300	MHYT domain
NO430_RS12075	COG0483	inositol monophosphate 1-phosphatase activity
NO430_RS12080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NO430_RS12100	COG0488	(ABC) transporter
NO430_RS12105	COG0513	Belongs to the DEAD box helicase family
NO430_RS12115	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NO430_RS12125	COG0625	glutathione transferase activity
NO430_RS12135	COG1671	Belongs to the UPF0178 family
NO430_RS12140	COG4681	YaeQ
NO430_RS12145	COG2081	HI0933 family
NO430_RS12150	COG5001	Diguanylate cyclase
NO430_RS12150	COG1716	ATPase activity
NO430_RS12155	COG0501	Belongs to the peptidase M48B family
NO430_RS12165	COG1028	Short-chain dehydrogenase reductase Sdr
NO430_RS12185	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NO430_RS12190	COG0860	N-Acetylmuramoyl-L-alanine amidase
NO430_RS12195	COG0802	atpase or kinase
NO430_RS12200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NO430_RS12200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NO430_RS12205	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NO430_RS12225	COG3039	Transposase
NO430_RS12230	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NO430_RS12275	COG0835	chemotaxis
NO430_RS12280	COG0840	transmembrane signaling receptor activity
NO430_RS12305	COG2969	positive regulation of protein catabolic process
NO430_RS12310	COG0625	glutathione transferase activity
NO430_RS12315	COG2857	Cytochrome c1
NO430_RS12320	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NO430_RS12325	COG0723	plastoquinol--plastocyanin reductase activity
NO430_RS12330	COG0741	lytic transglycosylase activity
NO430_RS12355	COG1702	phosphate starvation-inducible protein PhoH
NO430_RS12375	COG4535	Mg2 and Co2 transporter CorC
NO430_RS12390	COG1012	belongs to the aldehyde dehydrogenase family
NO430_RS12395	COG1177	transmembrane transport
NO430_RS12400	COG1176	ABC-type spermidine putrescine transport system, permease component I
NO430_RS12410	COG3842	ATPase activity
NO430_RS12435	COG3039	Transposase
NO430_RS12460	COG0174	glutamine synthetase
NO430_RS12465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO430_RS12475	COG0477	Major facilitator Superfamily
NO430_RS12485	COG0243	molybdopterin cofactor binding
NO430_RS12495	COG2223	nitrite transmembrane transporter activity
NO430_RS12500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NO430_RS12505	COG1121	(ABC) transporter
NO430_RS12515	COG2733	membrane
NO430_RS12520	COG0784	Response regulator, receiver
NO430_RS12520	COG2205	protein histidine kinase activity
NO430_RS12520	COG5002	protein histidine kinase activity
NO430_RS12530	COG3039	Transposase
NO430_RS12545	COG0300	oxidoreductase activity
NO430_RS12560	COG3039	Transposase
NO430_RS12570	COG2902	Dehydrogenase
NO430_RS12580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NO430_RS12585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NO430_RS12600	COG1609	Transcriptional regulator
NO430_RS12605	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NO430_RS12605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NO430_RS12610	COG1105	Belongs to the carbohydrate kinase PfkB family
NO430_RS12615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NO430_RS12615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NO430_RS12655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NO430_RS12665	COG1862	Preprotein translocase
NO430_RS12670	COG0343	queuine tRNA-ribosyltransferase activity
NO430_RS12725	COG0405	Gamma-glutamyltransferase
NO430_RS12730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NO430_RS12740	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NO430_RS12745	COG0742	ribosomal rna small subunit methyltransferase
NO430_RS12750	COG0326	Molecular chaperone. Has ATPase activity
NO430_RS12790	COG4206	TonB-dependent receptor
NO430_RS12820	COG3039	Transposase
NO430_RS12825	COG3039	Transposase
NO430_RS12835	COG0531	amino acid
NO430_RS12850	COG0006	proline dipeptidase activity
NO430_RS12860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NO430_RS12875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO430_RS12880	COG3938	Belongs to the proline racemase family
NO430_RS12890	COG0552	protein localization to endoplasmic reticulum
NO430_RS12900	COG1194	a g-specific adenine glycosylase
NO430_RS12910	COG0784	Response regulator, receiver
NO430_RS12910	COG4191	Histidine kinase
NO430_RS12915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NO430_RS12940	COG3040	lipid binding
NO430_RS12950	COG1960	acyl-CoA dehydrogenase activity
NO430_RS12960	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NO430_RS12990	COG0438	transferase activity, transferring glycosyl groups
NO430_RS13000	COG0438	transferase activity, transferring glycosyl groups
NO430_RS13005	COG0438	transferase activity, transferring glycosyl groups
NO430_RS13060	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NO430_RS13075	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NO430_RS13100	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NO430_RS13115	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NO430_RS13120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NO430_RS13125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NO430_RS13135	COG3115	cell septum assembly
NO430_RS13155	COG0360	Binds together with S18 to 16S ribosomal RNA
NO430_RS13160	COG0316	Belongs to the HesB IscA family
NO430_RS13190	COG0288	reversible hydration of carbon dioxide
NO430_RS13215	COG3844	kynureninase activity
NO430_RS13225	COG2925	Exonuclease
NO430_RS13235	COG0667	Aldo Keto reductase
NO430_RS13260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NO430_RS13260	COG0116	Belongs to the methyltransferase superfamily
NO430_RS13305	COG0494	nUDIX hydrolase
NO430_RS13315	COG1024	Enoyl-CoA hydratase
NO430_RS13325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NO430_RS13330	COG0659	secondary active sulfate transmembrane transporter activity
NO430_RS13355	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NO430_RS13360	COG0573	inorganic phosphate transmembrane transporter activity
NO430_RS13375	COG0704	Plays a role in the regulation of phosphate uptake
NO430_RS13385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NO430_RS13395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NO430_RS13410	COG0557	exoribonuclease II activity
NO430_RS13430	COG1960	acyl-CoA dehydrogenase activity
NO430_RS13435	COG2226	methyltransferase
NO430_RS13440	COG0646	methionine synthase
NO430_RS13440	COG1410	methionine synthase
NO430_RS13445	COG0646	methionine synthase
NO430_RS13445	COG1410	methionine synthase
NO430_RS13455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NO430_RS13465	COG1609	Transcriptional regulator
NO430_RS13480	COG2900	Belongs to the SlyX family
NO430_RS13495	COG0386	Belongs to the glutathione peroxidase family
NO430_RS13505	COG1725	Transcriptional regulator
NO430_RS13510	COG1131	(ABC) transporter
NO430_RS13540	COG3039	Transposase
NO430_RS13570	COG2850	peptidyl-arginine hydroxylation
NO430_RS13605	COG1132	(ABC) transporter
NO430_RS13635	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NO430_RS13640	COG0484	heat shock protein binding
NO430_RS13645	COG0443	Heat shock 70 kDa protein
NO430_RS13650	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NO430_RS13660	COG0497	DNA recombination
NO430_RS13670	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NO430_RS13680	COG2914	Belongs to the UPF0125 (RnfH) family
NO430_RS13690	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NO430_RS13705	COG0582	viral genome integration into host DNA
NO430_RS13715	COG3039	Transposase
NO430_RS13760	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NO430_RS13775	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NO430_RS13785	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NO430_RS13790	COG0174	glutamine synthetase
NO430_RS13850	COG0415	Belongs to the DNA photolyase family
NO430_RS13855	COG0305	Participates in initiation and elongation during chromosome replication
NO430_RS13865	COG0367	asparagine synthase
NO430_RS13895	COG0084	hydrolase, TatD family'
NO430_RS13900	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NO430_RS13935	COG0840	transmembrane signaling receptor activity
NO430_RS13950	COG3039	Transposase
NO430_RS13965	COG3039	Transposase
NO430_RS13995	COG0386	Belongs to the glutathione peroxidase family
NO430_RS14090	COG2814	Major facilitator Superfamily
NO430_RS14095	COG1566	PFAM secretion protein HlyD family protein
NO430_RS14110	COG2207	Transcriptional regulator
NO430_RS14130	COG4774	siderophore transport
NO430_RS14140	COG0367	asparagine synthase
NO430_RS14145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NO430_RS14155	COG1393	Belongs to the ArsC family
NO430_RS14215	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NO430_RS14230	COG0233	cytoplasmic translational termination
NO430_RS14240	COG0575	Belongs to the CDS family
NO430_RS14245	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NO430_RS14250	COG0750	zinc metalloprotease
NO430_RS14270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NO430_RS14275	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NO430_RS14295	COG0825	malonyl-CoA metabolic process
NO430_RS14320	COG1981	membrane
NO430_RS14365	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NO430_RS14380	COG2040	homocysteine
NO430_RS14385	COG0833	amino acid
NO430_RS14390	COG0346	lactoylglutathione lyase activity
NO430_RS14400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NO430_RS14400	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NO430_RS14410	COG2878	Part of a membrane complex involved in electron transport
NO430_RS14425	COG1595	DNA-templated transcription, initiation
NO430_RS14450	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NO430_RS14465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NO430_RS14470	COG0251	oxidation-reduction process
NO430_RS14480	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NO430_RS14480	COG0392	lysyltransferase activity
NO430_RS14515	COG2814	Major facilitator Superfamily
NO430_RS14520	COG1902	pentaerythritol trinitrate reductase activity
NO430_RS14530	COG2824	Alkylphosphonate utilization operon protein PhnA
NO430_RS14540	COG1047	Peptidyl-prolyl cis-trans
NO430_RS14580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NO430_RS14595	COG1451	nucleotide metabolic process
NO430_RS14620	COG0183	Belongs to the thiolase family
NO430_RS14650	COG1793	dna ligase
NO430_RS14650	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NO430_RS14660	COG1793	dna ligase
NO430_RS14665	COG1201	RNA secondary structure unwinding
NO430_RS14685	COG1278	Cold shock
NO430_RS14690	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NO430_RS14705	COG3046	protein related to deoxyribodipyrimidine photolyase
NO430_RS14710	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
NO430_RS14720	COG2954	triphosphatase activity
NO430_RS14735	COG1381	Involved in DNA repair and RecF pathway recombination
NO430_RS14760	COG0481	GTPase activity
NO430_RS14765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NO430_RS14780	COG1250	3-hydroxyacyl-CoA dehydrogenase
NO430_RS14780	COG1024	Enoyl-CoA hydratase
NO430_RS14800	COG1024	Enoyl-CoA hydratase
NO430_RS14805	COG1960	acyl-CoA dehydrogenase activity
NO430_RS14885	COG2353	YceI-like domain
NO430_RS14910	COG1760	l-serine dehydratase
NO430_RS14920	COG0626	cystathionine gamma-synthase activity
NO430_RS14925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NO430_RS14930	COG0739	heme binding
NO430_RS14940	COG1272	protein, Hemolysin III
NO430_RS14960	COG0517	IMP dehydrogenase activity
NO430_RS14960	COG0516	GMP reductase activity
NO430_RS14965	COG0463	Glycosyl transferase, family 2
NO430_RS14975	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NO430_RS14985	COG4771	TonB-dependent receptor
NO430_RS14990	COG1309	transcriptional regulator
NO430_RS15000	COG1960	acyl-CoA dehydrogenase activity
NO430_RS15025	COG0509	glycine decarboxylation via glycine cleavage system
NO430_RS15040	COG0330	HflC and HflK could
NO430_RS15050	COG1742	UPF0060 membrane protein
NO430_RS15055	COG3956	TIGRFAM MazG family protein
NO430_RS15065	COG0494	nUDIX hydrolase
NO430_RS15075	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NO430_RS15080	COG0837	glucose binding
NO430_RS15095	COG1388	LysM domain
NO430_RS15095	COG3858	chitin binding
NO430_RS15105	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NO430_RS15115	COG1472	Belongs to the glycosyl hydrolase 3 family
NO430_RS15150	COG2826	transposase and inactivated derivatives, IS30 family
NO430_RS15165	COG3039	Transposase
NO430_RS15225	COG3537	Alpha-1,2-mannosidase
NO430_RS15265	COG3142	Participates in the control of copper homeostasis
NO430_RS15270	COG1446	asparaginase
NO430_RS15275	COG2304	oxidoreductase activity
NO430_RS15295	COG2198	Histidine kinase
NO430_RS15295	COG0784	Response regulator, receiver
NO430_RS15295	COG0643	Histidine kinase
NO430_RS15300	COG0840	transmembrane signaling receptor activity
NO430_RS15305	COG0835	chemotaxis
NO430_RS15320	COG0189	ligase activity
NO430_RS15330	COG1397	ADP-ribosylglycohydrolase
NO430_RS15340	COG1199	ATP-dependent helicase activity
NO430_RS15350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NO430_RS15355	COG1215	transferase activity, transferring glycosyl groups
NO430_RS15365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NO430_RS15415	COG1643	Atp-dependent helicase
NO430_RS15420	COG0783	Belongs to the Dps family
NO430_RS15430	COG0514	ATP-dependent DNA helicase (RecQ)
NO430_RS15445	COG3039	Transposase
NO430_RS15450	COG1187	pseudouridine synthase activity
NO430_RS15490	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NO430_RS15500	COG0602	queuosine metabolic process
NO430_RS15510	COG2885	chlorophyll binding
NO430_RS15515	COG0823	Involved in the tonB-independent uptake of proteins
NO430_RS15525	COG0848	biopolymer transport protein
NO430_RS15535	COG0824	Thioesterase
NO430_RS15540	COG2255	four-way junction helicase activity
NO430_RS15555	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NO430_RS15575	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NO430_RS15590	COG0477	Major facilitator Superfamily
NO430_RS15625	COG0488	(ABC) transporter
NO430_RS15660	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NO430_RS15660	COG4651	solute:proton antiporter activity
NO430_RS15680	COG2391	methyltransferase activity
NO430_RS15690	COG0450	alkyl hydroperoxide reductase
NO430_RS15710	COG4772	TonB-dependent receptor
NO430_RS15720	COG4264	IucA IucC family
NO430_RS15725	COG2814	Major facilitator Superfamily
NO430_RS15735	COG0019	diaminopimelate decarboxylase activity
NO430_RS15795	COG4206	TonB-dependent receptor
NO430_RS15825	COG0542	response to heat
NO430_RS15850	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NO430_RS15860	COG0534	Mate efflux family protein
NO430_RS15875	COG0336	Belongs to the RNA methyltransferase TrmD family
NO430_RS15880	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NO430_RS15885	COG0228	four-way junction DNA binding
NO430_RS15910	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NO430_RS15915	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NO430_RS15955	COG2172	sigma factor antagonist activity
NO430_RS15960	COG1366	Belongs to the anti-sigma-factor antagonist family
NO430_RS15965	COG1366	Belongs to the anti-sigma-factor antagonist family
NO430_RS15975	COG0326	Molecular chaperone. Has ATPase activity
NO430_RS15980	COG2207	Transcriptional regulator
NO430_RS16035	COG3209	COG3209 Rhs family protein
NO430_RS16055	COG3209	COG3209 Rhs family protein
NO430_RS16080	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NO430_RS16085	COG1845	cytochrome c oxidase, subunit III
NO430_RS16090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NO430_RS16105	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NO430_RS16110	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NO430_RS16125	COG0728	peptidoglycan biosynthetic process
NO430_RS16130	COG0268	Binds directly to 16S ribosomal RNA
NO430_RS16135	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NO430_RS16140	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NO430_RS16150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NO430_RS16155	COG0824	Thioesterase
NO430_RS16170	COG1946	Acyl-CoA thioesterase
NO430_RS16195	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NO430_RS16235	COG1877	trehalose-phosphatase activity
NO430_RS16240	COG3387	PFAM Glycoside hydrolase 15-related
NO430_RS16285	COG0564	pseudouridine synthase activity
NO430_RS16290	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NO430_RS16295	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NO430_RS16295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NO430_RS16310	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NO430_RS16315	COG0045	succinate-CoA ligase (ADP-forming) activity
NO430_RS16360	COG2194	sulfuric ester hydrolase activity
NO430_RS16365	COG4969	Belongs to the N-Me-Phe pilin family
NO430_RS16375	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NO430_RS16380	COG0237	dephospho-CoA kinase activity
NO430_RS16385	COG2205	protein histidine kinase activity
NO430_RS16390	COG0745	RESPONSE REGULATOR receiver
NO430_RS16410	COG3039	Transposase
NO430_RS16435	COG3039	Transposase
NO430_RS16460	COG3039	Transposase
NO430_RS16485	COG2022	thiamine diphosphate biosynthetic process
NO430_RS16495	COG0471	metal ion transport
NO430_RS16495	COG3273	potassium ion transport
NO430_RS16525	COG1970	mechanosensitive ion channel activity
NO430_RS16565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NO430_RS16585	COG0308	aminopeptidase N
NO430_RS16590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NO430_RS16600	COG0529	Catalyzes the synthesis of activated sulfate
NO430_RS16600	COG2895	sulfate adenylyltransferase (ATP) activity
NO430_RS16605	COG0175	sulfate reduction
NO430_RS16610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NO430_RS16615	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NO430_RS16620	COG0175	sulfate reduction
NO430_RS16640	COG2205	protein histidine kinase activity
NO430_RS16640	COG0784	Response regulator, receiver
NO430_RS16640	COG2198	Histidine kinase
NO430_RS16680	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NO430_RS16685	COG3588	fructose-bisphosphate aldolase
NO430_RS16690	COG0469	pyruvate kinase activity
NO430_RS16715	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NO430_RS16725	COG3453	Protein conserved in bacteria
NO430_RS16725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NO430_RS16730	COG0725	ABC transporter, periplasmic molybdate-binding protein
NO430_RS16735	COG4149	molybdate abc transporter
NO430_RS16740	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NO430_RS16760	COG0642	Histidine kinase
NO430_RS16775	COG1028	Short-chain dehydrogenase reductase Sdr
NO430_RS16785	COG1022	Amp-dependent synthetase and ligase
NO430_RS16810	COG1376	ErfK ybiS ycfS ynhG family protein
NO430_RS16815	COG0739	heme binding
NO430_RS16825	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NO430_RS16830	COG1301	dicarboxylic acid transport
NO430_RS16850	COG2304	oxidoreductase activity
NO430_RS16870	COG0714	Associated with various cellular activities
NO430_RS16905	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NO430_RS16940	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NO430_RS16950	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NO430_RS16970	COG1561	YicC-like family, N-terminal region
NO430_RS16975	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NO430_RS16990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NO430_RS17025	COG0006	proline dipeptidase activity
NO430_RS17070	COG2912	Transglutaminase-like superfamily
NO430_RS17075	COG1773	rubredoxin
NO430_RS17080	COG0352	thiamine-phosphate diphosphorylase activity
NO430_RS17090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NO430_RS17100	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
NO430_RS17140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NO430_RS17170	COG0671	phosphoesterase, PA-phosphatase related
NO430_RS17180	COG3781	membrane
NO430_RS17190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NO430_RS17205	COG3039	Transposase
NO430_RS17220	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NO430_RS17230	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NO430_RS17255	COG3710	Transcriptional regulator
NO430_RS17260	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NO430_RS17270	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NO430_RS17300	COG2226	methyltransferase
NO430_RS17305	COG0066	3-isopropylmalate dehydratase activity
NO430_RS17310	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NO430_RS17330	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NO430_RS17335	COG1538	Outer membrane efflux protein
NO430_RS17340	COG1519	Transferase
NO430_RS17345	COG1560	Kdo2-lipid A biosynthetic process
NO430_RS17365	COG3039	Transposase
NO430_RS17370	COG2826	transposase and inactivated derivatives, IS30 family
NO430_RS17440	COG3039	Transposase
NO430_RS17455	COG0281	malic enzyme
NO430_RS17455	COG0280	phosphate acetyltransferase
NO430_RS17475	COG4191	Histidine kinase
NO430_RS17490	COG0583	DNA-binding transcription factor activity
NO430_RS17510	COG2197	response regulator
NO430_RS17520	COG0642	Histidine kinase
NO430_RS17535	COG2851	Citrate transporter
NO430_RS17540	COG1028	Short-chain dehydrogenase reductase Sdr
NO430_RS17545	COG1609	Transcriptional regulator
NO430_RS17555	COG2211	Major facilitator Superfamily
NO430_RS17585	COG0436	Aminotransferase
NO430_RS17605	COG0726	polysaccharide deacetylase
NO430_RS17610	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NO430_RS17630	COG0402	S-adenosylhomocysteine deaminase activity
NO430_RS17675	COG0242	peptide deformylase activity
NO430_RS17680	COG3039	Transposase
NO430_RS17710	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NO430_RS17765	COG2188	Transcriptional regulator
NO430_RS17780	COG1450	Type ii and iii secretion system protein
NO430_RS17795	COG3166	PFAM Fimbrial assembly family protein
NO430_RS17800	COG3156	type II secretion system protein K
NO430_RS17805	COG4795	General secretion pathway protein
NO430_RS17810	COG2165	general secretion pathway protein
NO430_RS17815	COG4970	Tfp pilus assembly protein FimT
NO430_RS17820	COG2165	general secretion pathway protein
NO430_RS17825	COG1459	type II secretion system
NO430_RS17835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NO430_RS17840	COG1404	Belongs to the peptidase S8 family
NO430_RS17845	COG5295	Hep Hag repeat protein
NO430_RS17850	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NO430_RS17850	COG0047	phosphoribosylformylglycinamidine synthase activity
NO430_RS17855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NO430_RS17860	COG4974	Belongs to the 'phage' integrase family
NO430_RS17875	COG0795	lipopolysaccharide-transporting ATPase activity
NO430_RS17885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NO430_RS17910	COG0525	valine-tRNA ligase activity
NO430_RS17940	COG2826	transposase and inactivated derivatives, IS30 family
NO430_RS17950	COG2826	transposase and inactivated derivatives, IS30 family
NO430_RS17970	COG1183	phosphatidylcholine synthase activity
NO430_RS17980	COG0442	prolyl-tRNA aminoacylation
NO430_RS17995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NO430_RS18000	COG1127	ABC transporter
NO430_RS18005	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NO430_RS18005	COG3218	ABC-type transport auxiliary lipoprotein component
NO430_RS18045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NO430_RS18050	COG0662	Cupin 2, conserved barrel domain protein
NO430_RS18050	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NO430_RS18075	COG2086	electron transfer activity
NO430_RS18145	COG0626	cystathionine gamma-synthase activity
NO430_RS18175	COG0625	glutathione transferase activity
NO430_RS18185	COG0513	Belongs to the DEAD box helicase family
NO430_RS18190	COG0720	synthase
NO430_RS18200	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NO430_RS18205	COG1956	GAF domain-containing protein
NO430_RS18215	COG0546	phosphoglycolate phosphatase activity
NO430_RS18240	COG0339	signal peptide processing
NO430_RS18290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NO430_RS18345	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NO430_RS18350	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NO430_RS18355	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NO430_RS18365	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NO430_RS18375	COG0356	it plays a direct role in the translocation of protons across the membrane
NO430_RS18395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NO430_RS18405	COG0508	dehydrogenase complex catalyzes the overall conversion of
NO430_RS18440	COG2011	ABC-type metal ion transport system permease component
NO430_RS18450	COG0697	spore germination
NO430_RS18485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NO430_RS18490	COG1187	pseudouridine synthase activity
NO430_RS18495	COG2813	Specifically methylates the guanine in position
NO430_RS18525	COG2205	protein histidine kinase activity
NO430_RS18525	COG2202	Pas domain
NO430_RS18550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO430_RS18600	COG0745	RESPONSE REGULATOR receiver
NO430_RS18615	COG1404	Belongs to the peptidase S8 family
NO430_RS18630	COG0842	Transport permease protein
NO430_RS18635	COG1131	(ABC) transporter
NO430_RS18640	COG0025	NhaP-type Na H and K H
NO430_RS18645	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NO430_RS18655	COG1573	uracil-dna glycosylase
NO430_RS18665	COG3384	dioxygenase
NO430_RS18690	COG3590	peptidase
NO430_RS18710	COG0531	amino acid
NO430_RS18735	COG3685	Protein conserved in bacteria
NO430_RS18740	COG3546	catalase activity
NO430_RS18760	COG3039	Transposase
NO430_RS18785	COG1271	oxidase subunit
NO430_RS18790	COG1294	oxidase, subunit
NO430_RS18820	COG1063	alcohol dehydrogenase
NO430_RS18920	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NO430_RS18920	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NO430_RS18930	COG1473	amidohydrolase
NO430_RS18935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NO430_RS18940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NO430_RS18965	COG5383	Protein conserved in bacteria
NO430_RS19010	COG3023	N-Acetylmuramoyl-L-alanine amidase
NO430_RS19020	COG4948	Mandelate Racemase Muconate Lactonizing
NO430_RS19040	COG0531	amino acid
NO430_RS19060	COG4682	membrane
NO430_RS19065	COG2133	pyrroloquinoline quinone binding
NO430_RS19080	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NO430_RS19085	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NO430_RS19095	COG1610	YqeY-like protein
NO430_RS19115	COG1295	ribonuclease BN
NO430_RS19120	COG0358	DNA primase activity
NO430_RS19185	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NO430_RS19200	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NO430_RS19265	COG0739	heme binding
NO430_RS19280	COG2211	Major facilitator Superfamily
NO430_RS19285	COG0708	Exodeoxyribonuclease III
NO430_RS19300	COG1192	Involved in chromosome partitioning
NO430_RS19305	COG1475	DNA binding
NO430_RS19320	COG0463	Glycosyl transferase, family 2
NO430_RS19345	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NO430_RS19370	COG4221	oxidoreductase activity
NO430_RS19385	COG3501	Rhs element vgr protein
NO430_RS19385	COG3409	Peptidoglycan-binding domain 1 protein
NO430_RS19410	COG1166	arginine decarboxylase activity
NO430_RS19415	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NO430_RS19455	COG0606	chelatase, subunit chli
NO430_RS19480	COG4943	cyclic-guanylate-specific phosphodiesterase activity
NO430_RS19500	COG3039	Transposase
NO430_RS19560	COG1090	epimerase
NO430_RS19580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NO430_RS19615	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NO430_RS19625	COG1595	DNA-templated transcription, initiation
NO430_RS19630	COG0753	catalase activity
NO430_RS19655	COG0697	spore germination
NO430_RS19675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NO430_RS19680	COG0180	Tryptophanyl-tRNA synthetase
NO430_RS19685	COG3237	CsbD-like
NO430_RS19700	COG0010	Belongs to the arginase family
NO430_RS19720	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NO430_RS19735	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NO430_RS19740	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NO430_RS19740	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NO430_RS19750	COG3228	Belongs to the MtfA family
NO430_RS19780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NO430_RS19795	COG3501	Rhs element vgr protein
NO430_RS19795	COG3409	Peptidoglycan-binding domain 1 protein
NO430_RS19830	COG3039	Transposase
NO430_RS19845	COG1199	ATP-dependent helicase activity
NO430_RS19885	COG0583	DNA-binding transcription factor activity
NO430_RS19930	COG0625	glutathione transferase activity
NO430_RS19965	COG4555	ABC transporter
NO430_RS19975	COG1476	TRANSCRIPTIONal
NO430_RS19990	COG1230	cation diffusion facilitator family transporter
NO430_RS19995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NO430_RS20000	COG1131	(ABC) transporter
NO430_RS20005	COG0842	Transport permease protein
NO430_RS20015	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NO430_RS20050	COG2951	lytic endotransglycosylase activity
NO430_RS20065	COG1196	nuclear chromosome segregation
NO430_RS20070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NO430_RS20075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NO430_RS20095	COG2239	Acts as a magnesium transporter
NO430_RS20115	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NO430_RS20120	COG3387	PFAM Glycoside hydrolase 15-related
NO430_RS20135	COG3100	YcgL domain-containing protein
NO430_RS20140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NO430_RS20150	COG0463	Glycosyl transferase, family 2
NO430_RS20165	COG1028	Short-chain dehydrogenase reductase Sdr
NO430_RS20210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO430_RS20250	COG0408	coproporphyrinogen oxidase activity
NO430_RS20325	COG0210	DNA helicase
NO430_RS20340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NO430_RS20355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NO430_RS20365	COG2159	amidohydrolase
NO430_RS20390	COG0357	Ribosomal RNA small subunit methyltransferase G
NO430_RS20395	COG3540	Alkaline phosphatase
NO430_RS20405	COG2091	lysine biosynthetic process via aminoadipic acid
NO430_RS20420	COG0708	Exodeoxyribonuclease III
NO430_RS20435	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NO430_RS20440	COG3162	membrane
NO430_RS20500	COG1028	Short-chain dehydrogenase reductase Sdr
NO430_RS20505	COG0179	Fumarylacetoacetate (FAA) hydrolase
NO430_RS20510	COG4948	Mandelate Racemase Muconate Lactonizing
NO430_RS20515	COG3254	rhamnose metabolic process
NO430_RS20520	COG0738	Major facilitator superfamily
NO430_RS20525	COG1414	Transcriptional regulator
NO430_RS20535	COG2205	protein histidine kinase activity
NO430_RS20545	COG3459	Glycosyltransferase 36 associated
NO430_RS20550	COG2211	Major facilitator Superfamily
NO430_RS20555	COG3265	gluconokinase activity
NO430_RS20560	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NO430_RS20590	COG3039	Transposase
NO430_RS20600	COG3039	Transposase
NO430_RS20605	COG2911	Protein conserved in bacteria
NO430_RS20610	COG0729	surface antigen
NO430_RS20615	COG4771	TonB-dependent receptor
NO430_RS20620	COG0457	Tetratricopeptide repeat
NO430_RS20630	COG0752	glycyl-tRNA synthetase alpha subunit
NO430_RS20635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NO430_RS20645	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NO430_RS20645	COG0519	Catalyzes the synthesis of GMP from XMP
NO430_RS20655	COG0805	protein transport
NO430_RS20660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NO430_RS20665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NO430_RS20675	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NO430_RS20700	COG2974	May be involved in recombination
NO430_RS20705	COG0037	tRNA processing
NO430_RS20725	COG3661	Belongs to the glycosyl hydrolase 67 family
NO430_RS20735	COG4948	Mandelate Racemase Muconate Lactonizing
NO430_RS20745	COG1472	Belongs to the glycosyl hydrolase 3 family
NO430_RS20750	COG0246	Mannitol dehydrogenase
NO430_RS20780	COG2826	transposase and inactivated derivatives, IS30 family
NO430_RS20800	COG3693	PFAM glycoside hydrolase, family 10
NO430_RS20825	COG2211	Major facilitator Superfamily
NO430_RS20840	COG3039	Transposase
NO430_RS20870	COG2937	Belongs to the GPAT DAPAT family
NO430_RS20905	COG0284	orotidine-5'-phosphate decarboxylase activity
NO430_RS20910	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NO430_RS20915	COG3132	Protein of unknown function, DUF480
NO430_RS20930	COG0210	DNA helicase
NO430_RS20945	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NO430_RS20955	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NO430_RS21025	COG0730	response to heat
NO430_RS21060	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NO430_RS21065	COG0302	gtp cyclohydrolase
NO430_RS21100	COG2826	transposase and inactivated derivatives, IS30 family
NO430_RS21105	COG0477	Major facilitator Superfamily
NO430_RS21165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NO430_RS21215	COG3237	CsbD-like
NO430_RS21240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NO430_RS21275	COG1304	FMN binding
NO430_RS21295	COG4772	TonB-dependent receptor
NO430_RS21305	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NO430_RS21335	COG3039	Transposase
NO430_RS21385	COG0564	pseudouridine synthase activity
NO430_RS21395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NO430_RS21410	COG3039	Transposase
NO430_RS21425	COG3039	Transposase
NO430_RS21440	COG3039	Transposase
NO430_RS21510	COG1074	ATP-dependent DNA helicase activity
NO430_RS21515	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NO430_RS21520	COG1116	anion transmembrane transporter activity
NO430_RS21530	COG3039	Transposase
NO430_RS21535	COG3039	Transposase
NO430_RS21550	COG1136	(ABC) transporter
NO430_RS21570	COG1127	ABC transporter
NO430_RS21575	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NO430_RS21580	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NO430_RS21595	COG2853	Lipoprotein
NO430_RS21615	COG0386	Belongs to the glutathione peroxidase family
NO430_RS21625	COG1322	Protein conserved in bacteria
NO430_RS21630	COG3039	Transposase
NO430_RS21655	COG1929	Belongs to the glycerate kinase type-1 family
NO430_RS21660	COG2271	Major facilitator Superfamily
NO430_RS21675	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NO430_RS21680	COG0861	Integral membrane protein TerC family
NO430_RS21690	COG0584	glycerophosphoryl diester phosphodiesterase
NO430_RS21700	COG0671	phosphoesterase, PA-phosphatase related
NO430_RS21705	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NO430_RS21710	COG0726	polysaccharide deacetylase
NO430_RS21765	COG3504	Conjugal transfer protein
NO430_RS21770	COG2948	multi-organism process
NO430_RS21825	COG2003	Belongs to the UPF0758 family