locus-tag	class	description
LUZ17_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LUZ17_RS00020	COG0187	DNA topoisomerase II activity
LUZ17_RS00030	COG0501	Belongs to the peptidase M48B family
LUZ17_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LUZ17_RS00080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LUZ17_RS00090	COG4772	TonB-dependent receptor
LUZ17_RS00105	COG3039	Transposase
LUZ17_RS00110	COG1304	FMN binding
LUZ17_RS00140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUZ17_RS00150	COG3039	Transposase
LUZ17_RS00160	COG1136	(ABC) transporter
LUZ17_RS00205	COG3039	Transposase
LUZ17_RS00210	COG0513	Belongs to the DEAD box helicase family
LUZ17_RS00260	COG3039	Transposase
LUZ17_RS00305	COG1858	cytochrome C peroxidase
LUZ17_RS00320	COG0702	epimerase
LUZ17_RS00345	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LUZ17_RS00365	COG1649	PFAM Uncharacterised BCR, COG1649
LUZ17_RS00370	COG2354	Protein conserved in bacteria
LUZ17_RS00375	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LUZ17_RS00390	COG3264	Mechanosensitive ion channel
LUZ17_RS00390	COG1511	domain protein
LUZ17_RS00465	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LUZ17_RS00575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LUZ17_RS00595	COG1090	epimerase
LUZ17_RS00605	COG3039	Transposase
LUZ17_RS00630	COG2826	transposase and inactivated derivatives, IS30 family
LUZ17_RS00690	COG1136	(ABC) transporter
LUZ17_RS00730	COG1272	protein, Hemolysin III
LUZ17_RS00735	COG1111	helicase
LUZ17_RS00735	COG1205	dead DEAH box helicase
LUZ17_RS00795	COG0067	glutamate synthase
LUZ17_RS00795	COG0069	glutamate synthase activity
LUZ17_RS00795	COG0070	glutamate synthase
LUZ17_RS00800	COG0493	'glutamate synthase
LUZ17_RS00850	COG1609	Transcriptional regulator
LUZ17_RS00875	COG0366	Alpha amylase catalytic
LUZ17_RS00880	COG0366	Alpha amylase catalytic
LUZ17_RS00925	COG0606	chelatase, subunit chli
LUZ17_RS00965	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LUZ17_RS00970	COG1166	arginine decarboxylase activity
LUZ17_RS01035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LUZ17_RS01060	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_RS01085	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LUZ17_RS01100	COG0210	DNA helicase
LUZ17_RS01115	COG3132	Protein of unknown function, DUF480
LUZ17_RS01120	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LUZ17_RS01125	COG0284	orotidine-5'-phosphate decarboxylase activity
LUZ17_RS01160	COG2937	Belongs to the GPAT DAPAT family
LUZ17_RS01165	COG0604	alcohol dehydrogenase
LUZ17_RS01165	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_RS01165	COG3321	synthase
LUZ17_RS01200	COG3186	Phenylalanine-4-hydroxylase
LUZ17_RS01205	COG1522	sequence-specific DNA binding
LUZ17_RS01250	COG1064	alcohol dehydrogenase
LUZ17_RS01255	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LUZ17_RS01265	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LUZ17_RS01275	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LUZ17_RS01300	COG3039	Transposase
LUZ17_RS01305	COG0676	glucose-6-phosphate 1-epimerase activity
LUZ17_RS01370	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LUZ17_RS01390	COG2853	Lipoprotein
LUZ17_RS01405	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LUZ17_RS01410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LUZ17_RS01415	COG1127	ABC transporter
LUZ17_RS01490	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUZ17_RS01500	COG3265	gluconokinase activity
LUZ17_RS01505	COG2211	Major facilitator Superfamily
LUZ17_RS01510	COG3459	Glycosyltransferase 36 associated
LUZ17_RS01520	COG2205	protein histidine kinase activity
LUZ17_RS01530	COG1414	Transcriptional regulator
LUZ17_RS01535	COG0738	Major facilitator superfamily
LUZ17_RS01540	COG3254	rhamnose metabolic process
LUZ17_RS01570	COG0339	signal peptide processing
LUZ17_RS01600	COG0564	pseudouridine synthase activity
LUZ17_RS01610	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LUZ17_RS01620	COG1181	Belongs to the D-alanine--D-alanine ligase family
LUZ17_RS01630	COG3039	Transposase
LUZ17_RS01710	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LUZ17_RS01720	COG0842	Transport permease protein
LUZ17_RS01725	COG1131	(ABC) transporter
LUZ17_RS01730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LUZ17_RS01755	COG1476	TRANSCRIPTIONal
LUZ17_RS01765	COG4555	ABC transporter
LUZ17_RS01800	COG0625	glutathione transferase activity
LUZ17_RS01845	COG0583	DNA-binding transcription factor activity
LUZ17_RS01885	COG1199	ATP-dependent helicase activity
LUZ17_RS01925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LUZ17_RS01955	COG3228	Belongs to the MtfA family
LUZ17_RS01965	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LUZ17_RS01965	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LUZ17_RS01970	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LUZ17_RS01985	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LUZ17_RS02020	COG3237	CsbD-like
LUZ17_RS02025	COG0180	Tryptophanyl-tRNA synthetase
LUZ17_RS02030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUZ17_RS02075	COG0753	catalase activity
LUZ17_RS02080	COG1595	DNA-templated transcription, initiation
LUZ17_RS02090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LUZ17_RS02100	COG0628	permease
LUZ17_RS02110	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LUZ17_RS02115	COG1040	competence protein
LUZ17_RS02120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LUZ17_RS02125	COG0156	8-amino-7-oxononanoate synthase activity
LUZ17_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_RS02150	COG0463	Glycosyl transferase, family 2
LUZ17_RS02160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LUZ17_RS02165	COG3100	YcgL domain-containing protein
LUZ17_RS02180	COG3387	PFAM Glycoside hydrolase 15-related
LUZ17_RS02185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LUZ17_RS02200	COG2239	Acts as a magnesium transporter
LUZ17_RS02210	COG1042	CoA-binding domain protein
LUZ17_RS02210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUZ17_RS02210	COG0045	succinate-CoA ligase (ADP-forming) activity
LUZ17_RS02220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LUZ17_RS02225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LUZ17_RS02260	COG3485	protocatechuate 3,4-dioxygenase
LUZ17_RS02265	COG3485	protocatechuate 3,4-dioxygenase
LUZ17_RS02280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LUZ17_RS02285	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LUZ17_RS02310	COG4221	oxidoreductase activity
LUZ17_RS02325	COG0018	arginyl-trna synthetase
LUZ17_RS02330	COG2003	Belongs to the UPF0758 family
LUZ17_RS02335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LUZ17_RS02360	COG0463	Glycosyl transferase, family 2
LUZ17_RS02375	COG1475	DNA binding
LUZ17_RS02380	COG1192	Involved in chromosome partitioning
LUZ17_RS02395	COG0708	Exodeoxyribonuclease III
LUZ17_RS02400	COG2211	Major facilitator Superfamily
LUZ17_RS02415	COG0739	heme binding
LUZ17_RS02460	COG0745	RESPONSE REGULATOR receiver
LUZ17_RS02500	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LUZ17_RS02515	COG2814	Major facilitator Superfamily
LUZ17_RS02530	COG1289	transmembrane transporter activity
LUZ17_RS02540	COG0577	efflux transmembrane transporter activity
LUZ17_RS02540	COG1136	(ABC) transporter
LUZ17_RS02545	COG0151	Belongs to the GarS family
LUZ17_RS02555	COG0419	ATPase involved in DNA repair
LUZ17_RS02590	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LUZ17_RS02630	COG0439	Biotin carboxylase
LUZ17_RS02640	COG0511	ligase activity, forming carbon-carbon bonds
LUZ17_RS02645	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LUZ17_RS02655	COG1324	tolerance protein
LUZ17_RS02690	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LUZ17_RS02710	COG0534	Mate efflux family protein
LUZ17_RS02715	COG0616	signal peptide processing
LUZ17_RS02725	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_RS02740	COG0009	L-threonylcarbamoyladenylate synthase
LUZ17_RS02745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LUZ17_RS02745	COG1754	DNA topoisomerase type I activity
LUZ17_RS02760	COG2922	Belongs to the Smg family
LUZ17_RS02765	COG0758	DNA mediated transformation
LUZ17_RS02770	COG1652	LysM domain
LUZ17_RS02775	COG0242	peptide deformylase activity
LUZ17_RS02780	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LUZ17_RS02785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LUZ17_RS02785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LUZ17_RS02835	COG1560	Kdo2-lipid A biosynthetic process
LUZ17_RS02845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LUZ17_RS03070	COG1294	oxidase, subunit
LUZ17_RS03075	COG1271	oxidase subunit
LUZ17_RS03085	COG2204	response regulator
LUZ17_RS03110	COG2972	Histidine kinase
LUZ17_RS03125	COG0531	amino acid
LUZ17_RS03145	COG3590	peptidase
LUZ17_RS03160	COG0667	Aldo Keto reductase
LUZ17_RS03175	COG3384	dioxygenase
LUZ17_RS03185	COG1573	uracil-dna glycosylase
LUZ17_RS03195	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LUZ17_RS03205	COG0025	NhaP-type Na H and K H
LUZ17_RS03210	COG1131	(ABC) transporter
LUZ17_RS03215	COG0842	Transport permease protein
LUZ17_RS03235	COG1404	Belongs to the peptidase S8 family
LUZ17_RS03250	COG0745	RESPONSE REGULATOR receiver
LUZ17_RS03300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUZ17_RS03325	COG2202	Pas domain
LUZ17_RS03325	COG2205	protein histidine kinase activity
LUZ17_RS03355	COG2813	Specifically methylates the guanine in position
LUZ17_RS03360	COG1187	pseudouridine synthase activity
LUZ17_RS03365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LUZ17_RS03400	COG0697	spore germination
LUZ17_RS03410	COG2011	ABC-type metal ion transport system permease component
LUZ17_RS03440	COG0508	dehydrogenase complex catalyzes the overall conversion of
LUZ17_RS03450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LUZ17_RS03470	COG0356	it plays a direct role in the translocation of protons across the membrane
LUZ17_RS03480	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LUZ17_RS03490	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LUZ17_RS03495	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LUZ17_RS03500	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LUZ17_RS03505	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LUZ17_RS03555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUZ17_RS03560	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LUZ17_RS03615	COG0339	signal peptide processing
LUZ17_RS03650	COG1956	GAF domain-containing protein
LUZ17_RS03655	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LUZ17_RS03665	COG0720	synthase
LUZ17_RS03670	COG0513	Belongs to the DEAD box helicase family
LUZ17_RS03680	COG0625	glutathione transferase activity
LUZ17_RS03710	COG0626	cystathionine gamma-synthase activity
LUZ17_RS03750	COG3328	transposase activity
LUZ17_RS03775	COG2086	electron transfer activity
LUZ17_RS03800	COG0662	Cupin 2, conserved barrel domain protein
LUZ17_RS03800	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LUZ17_RS03805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LUZ17_RS03840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LUZ17_RS03840	COG3218	ABC-type transport auxiliary lipoprotein component
LUZ17_RS03845	COG1127	ABC transporter
LUZ17_RS03850	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LUZ17_RS03865	COG0442	prolyl-tRNA aminoacylation
LUZ17_RS03875	COG1183	phosphatidylcholine synthase activity
LUZ17_RS03900	COG3039	Transposase
LUZ17_RS03955	COG0525	valine-tRNA ligase activity
LUZ17_RS03970	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LUZ17_RS03980	COG0795	lipopolysaccharide-transporting ATPase activity
LUZ17_RS03995	COG4974	Belongs to the 'phage' integrase family
LUZ17_RS04000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LUZ17_RS04005	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LUZ17_RS04005	COG0047	phosphoribosylformylglycinamidine synthase activity
LUZ17_RS04010	COG5295	Hep Hag repeat protein
LUZ17_RS04030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LUZ17_RS04040	COG1459	type II secretion system
LUZ17_RS04045	COG2165	general secretion pathway protein
LUZ17_RS04050	COG4970	Tfp pilus assembly protein FimT
LUZ17_RS04055	COG2165	general secretion pathway protein
LUZ17_RS04060	COG4795	General secretion pathway protein
LUZ17_RS04065	COG3156	type II secretion system protein K
LUZ17_RS04070	COG3166	PFAM Fimbrial assembly family protein
LUZ17_RS04085	COG1450	Type ii and iii secretion system protein
LUZ17_RS04100	COG2188	Transcriptional regulator
LUZ17_RS04150	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LUZ17_RS04155	COG1518	maintenance of DNA repeat elements
LUZ17_RS04195	COG1399	metal-binding, possibly nucleic acid-binding protein
LUZ17_RS04220	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_RS04225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LUZ17_RS04235	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LUZ17_RS04240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LUZ17_RS04275	COG3829	transcription factor binding
LUZ17_RS04355	COG2826	transposase and inactivated derivatives, IS30 family
LUZ17_RS04365	COG0678	peroxiredoxin activity
LUZ17_RS04385	COG0330	HflC and HflK could
LUZ17_RS04390	COG0330	HflC and HflK could
LUZ17_RS04405	COG0308	aminopeptidase N
LUZ17_RS04455	COG1560	Kdo2-lipid A biosynthetic process
LUZ17_RS04460	COG1519	Transferase
LUZ17_RS04465	COG1538	Outer membrane efflux protein
LUZ17_RS04470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LUZ17_RS04500	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LUZ17_RS04505	COG0066	3-isopropylmalate dehydratase activity
LUZ17_RS04540	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LUZ17_RS04550	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LUZ17_RS04555	COG3710	Transcriptional regulator
LUZ17_RS04580	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LUZ17_RS04600	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LUZ17_RS04630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LUZ17_RS04640	COG3781	membrane
LUZ17_RS04655	COG0625	glutathione transferase activity
LUZ17_RS04665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LUZ17_RS04670	COG1217	gtp-binding protein TYPA
LUZ17_RS04690	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LUZ17_RS04820	COG3039	Transposase
LUZ17_RS04840	COG0584	glycerophosphoryl diester phosphodiesterase
LUZ17_RS04865	COG0473	3-isopropylmalate dehydrogenase activity
LUZ17_RS04915	COG0544	peptidyl-prolyl cis-trans isomerase activity
LUZ17_RS04955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LUZ17_RS04980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LUZ17_RS04990	COG0631	protein serine/threonine phosphatase activity
LUZ17_RS05065	COG0582	viral genome integration into host DNA
LUZ17_RS05075	COG0859	PFAM glycosyl transferase family 9
LUZ17_RS05080	COG3642	lipopolysaccharide core region biosynthetic process
LUZ17_RS05085	COG1234	tRNA 3'-trailer cleavage
LUZ17_RS05090	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LUZ17_RS05100	COG0315	cyclic pyranopterin monophosphate synthase activity
LUZ17_RS05105	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LUZ17_RS05110	COG0314	molybdopterin synthase activity
LUZ17_RS05140	COG0537	adenosine 5'-monophosphoramidase activity
LUZ17_RS05160	COG0714	Associated with various cellular activities
LUZ17_RS05180	COG0242	peptide deformylase activity
LUZ17_RS05225	COG3039	Transposase
LUZ17_RS05250	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LUZ17_RS05255	COG0726	polysaccharide deacetylase
LUZ17_RS05305	COG2211	Major facilitator Superfamily
LUZ17_RS05315	COG1609	Transcriptional regulator
LUZ17_RS05320	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_RS05325	COG2851	Citrate transporter
LUZ17_RS05340	COG0642	Histidine kinase
LUZ17_RS05350	COG2197	response regulator
LUZ17_RS05370	COG0583	DNA-binding transcription factor activity
LUZ17_RS05385	COG4191	Histidine kinase
LUZ17_RS05405	COG0280	phosphate acetyltransferase
LUZ17_RS05405	COG0281	malic enzyme
LUZ17_RS05435	COG0352	thiamine-phosphate diphosphorylase activity
LUZ17_RS05440	COG1773	rubredoxin
LUZ17_RS05445	COG2912	Transglutaminase-like superfamily
LUZ17_RS05465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LUZ17_RS05490	COG0006	proline dipeptidase activity
LUZ17_RS05530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LUZ17_RS05545	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LUZ17_RS05550	COG1561	YicC-like family, N-terminal region
LUZ17_RS05575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LUZ17_RS05585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LUZ17_RS05615	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LUZ17_RS05665	COG0714	Associated with various cellular activities
LUZ17_RS05685	COG2304	oxidoreductase activity
LUZ17_RS05705	COG1301	dicarboxylic acid transport
LUZ17_RS05710	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LUZ17_RS05720	COG0739	heme binding
LUZ17_RS05725	COG1376	ErfK ybiS ycfS ynhG family protein
LUZ17_RS05750	COG1022	Amp-dependent synthetase and ligase
LUZ17_RS05760	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_RS05775	COG0642	Histidine kinase
LUZ17_RS05795	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LUZ17_RS05800	COG4149	molybdate abc transporter
LUZ17_RS05805	COG0725	ABC transporter, periplasmic molybdate-binding protein
LUZ17_RS05810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUZ17_RS05810	COG3453	Protein conserved in bacteria
LUZ17_RS05840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LUZ17_RS05860	COG2205	protein histidine kinase activity
LUZ17_RS05865	COG0745	RESPONSE REGULATOR receiver
LUZ17_RS05910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LUZ17_RS05915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LUZ17_RS05960	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LUZ17_RS06010	COG2201	protein-glutamate methylesterase activity
LUZ17_RS06040	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LUZ17_RS06050	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LUZ17_RS06055	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LUZ17_RS06070	COG1842	Phage shock protein A
LUZ17_RS06095	COG0754	glutathionylspermidine amidase activity
LUZ17_RS06155	COG0531	amino acid
LUZ17_RS06160	COG2197	response regulator
LUZ17_RS06175	COG1113	amino acid transport
LUZ17_RS06190	COG1271	oxidase subunit
LUZ17_RS06195	COG1294	oxidase, subunit
LUZ17_RS06205	COG2239	Acts as a magnesium transporter
LUZ17_RS06210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LUZ17_RS06215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUZ17_RS06225	COG1660	Displays ATPase and GTPase activities
LUZ17_RS06230	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LUZ17_RS06235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUZ17_RS06250	COG1137	ATPase activity
LUZ17_RS06255	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LUZ17_RS06265	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LUZ17_RS06275	COG0271	Belongs to the BolA IbaG family
LUZ17_RS06280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LUZ17_RS06300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LUZ17_RS06315	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LUZ17_RS06325	COG0628	permease
LUZ17_RS06335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LUZ17_RS06340	COG3178	'Phosphotransferase
LUZ17_RS06355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LUZ17_RS06360	COG1555	photosystem II stabilization
LUZ17_RS06400	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LUZ17_RS06410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LUZ17_RS06430	COG0228	four-way junction DNA binding
LUZ17_RS06435	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LUZ17_RS06440	COG0336	Belongs to the RNA methyltransferase TrmD family
LUZ17_RS06455	COG0534	Mate efflux family protein
LUZ17_RS06490	COG0542	response to heat
LUZ17_RS06525	COG4206	TonB-dependent receptor
LUZ17_RS06590	COG0019	diaminopimelate decarboxylase activity
LUZ17_RS06600	COG2814	Major facilitator Superfamily
LUZ17_RS06605	COG4264	IucA IucC family
LUZ17_RS06615	COG4772	TonB-dependent receptor
LUZ17_RS06630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LUZ17_RS06630	COG4651	solute:proton antiporter activity
LUZ17_RS06665	COG0488	(ABC) transporter
LUZ17_RS06690	COG0657	acetylesterase activity
LUZ17_RS06690	COG2755	lipolytic protein G-D-S-L family
LUZ17_RS06720	COG2207	Transcriptional regulator
LUZ17_RS06725	COG0326	Molecular chaperone. Has ATPase activity
LUZ17_RS06750	COG3328	transposase activity
LUZ17_RS06755	COG0174	glutamine synthetase
LUZ17_RS06760	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LUZ17_RS06770	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LUZ17_RS06785	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LUZ17_RS06820	COG2146	nitrite reductase [NAD(P)H] activity
LUZ17_RS06830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LUZ17_RS06835	COG0719	Fe-S assembly protein
LUZ17_RS06840	COG0396	ATPase activity
LUZ17_RS06845	COG0719	Fe-S assembly protein
LUZ17_RS06850	COG1959	2 iron, 2 sulfur cluster binding
LUZ17_RS06910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LUZ17_RS06935	COG0519	Catalyzes the synthesis of GMP from XMP
LUZ17_RS06950	COG1678	Uncharacterized ACR, COG1678
LUZ17_RS06955	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LUZ17_RS06970	COG1764	response to oxidative stress
LUZ17_RS06980	COG0384	phenazine biosynthesis protein PhzF
LUZ17_RS06990	COG0527	aspartate kinase activity
LUZ17_RS07015	COG0142	geranyltranstransferase activity
LUZ17_RS07020	COG0629	single-stranded DNA binding
LUZ17_RS07025	COG2203	Gaf domain
LUZ17_RS07025	COG4251	negative regulation of phosphorylation
LUZ17_RS07025	COG3706	GGDEF domain
LUZ17_RS07025	COG5001	Diguanylate cyclase
LUZ17_RS07060	COG2879	small protein
LUZ17_RS07065	COG1966	Carbon starvation protein
LUZ17_RS07070	COG1741	Belongs to the pirin family
LUZ17_RS07160	COG1741	Belongs to the pirin family
LUZ17_RS07170	COG1515	deoxyribonuclease V activity
LUZ17_RS07190	COG3590	peptidase
LUZ17_RS07205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LUZ17_RS07210	COG2199	diguanylate cyclase activity
LUZ17_RS07210	COG2200	EAL domain
LUZ17_RS07210	COG2202	Pas domain
LUZ17_RS07215	COG0835	chemotaxis
LUZ17_RS07220	COG0840	transmembrane signaling receptor activity
LUZ17_RS07225	COG2198	Histidine kinase
LUZ17_RS07225	COG0643	Histidine kinase
LUZ17_RS07240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LUZ17_RS07250	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LUZ17_RS07350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LUZ17_RS07355	COG0735	belongs to the Fur family
LUZ17_RS07415	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LUZ17_RS07420	COG0084	hydrolase, TatD family'
LUZ17_RS07435	COG1960	acyl-CoA dehydrogenase activity
LUZ17_RS07450	COG0367	asparagine synthase
LUZ17_RS07460	COG0305	Participates in initiation and elongation during chromosome replication
LUZ17_RS07465	COG0415	Belongs to the DNA photolyase family
LUZ17_RS07585	COG5002	protein histidine kinase activity
LUZ17_RS07585	COG5001	Diguanylate cyclase
LUZ17_RS07590	COG1187	pseudouridine synthase activity
LUZ17_RS07610	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LUZ17_RS07620	COG0475	glutathione-regulated potassium exporter activity
LUZ17_RS07625	COG5000	phosphorelay sensor kinase activity
LUZ17_RS07625	COG5002	protein histidine kinase activity
LUZ17_RS07630	COG0745	RESPONSE REGULATOR receiver
LUZ17_RS07660	COG1132	(ABC) transporter
LUZ17_RS07690	COG3039	Transposase
LUZ17_RS07715	COG3039	Transposase
LUZ17_RS07750	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LUZ17_RS07760	COG4969	Belongs to the N-Me-Phe pilin family
LUZ17_RS07765	COG2194	sulfuric ester hydrolase activity
LUZ17_RS07785	COG2184	nucleotidyltransferase activity
LUZ17_RS07810	COG0045	succinate-CoA ligase (ADP-forming) activity
LUZ17_RS07815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LUZ17_RS07830	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LUZ17_RS07830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LUZ17_RS07835	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUZ17_RS07840	COG0564	pseudouridine synthase activity
LUZ17_RS07865	COG3387	PFAM Glycoside hydrolase 15-related
LUZ17_RS07870	COG1877	trehalose-phosphatase activity
LUZ17_RS07910	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LUZ17_RS07940	COG1946	Acyl-CoA thioesterase
LUZ17_RS07955	COG0824	Thioesterase
LUZ17_RS07960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LUZ17_RS07970	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LUZ17_RS07975	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LUZ17_RS07980	COG0268	Binds directly to 16S ribosomal RNA
LUZ17_RS07985	COG0728	peptidoglycan biosynthetic process
LUZ17_RS07990	COG0196	riboflavin kinase activity
LUZ17_RS08000	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LUZ17_RS08005	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LUZ17_RS08020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LUZ17_RS08025	COG1845	cytochrome c oxidase, subunit III
LUZ17_RS08030	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LUZ17_RS08050	COG3209	COG3209 Rhs family protein
LUZ17_RS08165	COG0632	four-way junction helicase activity
LUZ17_RS08175	COG2255	four-way junction helicase activity
LUZ17_RS08180	COG0824	Thioesterase
LUZ17_RS08190	COG0848	biopolymer transport protein
LUZ17_RS08205	COG2885	chlorophyll binding
LUZ17_RS08215	COG0602	queuosine metabolic process
LUZ17_RS08220	COG1187	pseudouridine synthase activity
LUZ17_RS08275	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LUZ17_RS08300	COG0514	ATP-dependent DNA helicase (RecQ)
LUZ17_RS08305	COG0783	Belongs to the Dps family
LUZ17_RS08310	COG1643	Atp-dependent helicase
LUZ17_RS08365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LUZ17_RS08375	COG1215	transferase activity, transferring glycosyl groups
LUZ17_RS08380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LUZ17_RS08390	COG1199	ATP-dependent helicase activity
LUZ17_RS08400	COG1397	ADP-ribosylglycohydrolase
LUZ17_RS08410	COG0189	ligase activity
LUZ17_RS08425	COG0835	chemotaxis
LUZ17_RS08430	COG0840	transmembrane signaling receptor activity
LUZ17_RS08435	COG0643	Histidine kinase
LUZ17_RS08435	COG0784	Response regulator, receiver
LUZ17_RS08435	COG2198	Histidine kinase
LUZ17_RS08460	COG2304	oxidoreductase activity
LUZ17_RS08465	COG2304	oxidoreductase activity
LUZ17_RS08475	COG1446	asparaginase
LUZ17_RS08480	COG3142	Participates in the control of copper homeostasis
LUZ17_RS08530	COG3537	Alpha-1,2-mannosidase
LUZ17_RS08605	COG1472	Belongs to the glycosyl hydrolase 3 family
LUZ17_RS08615	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LUZ17_RS08625	COG1388	LysM domain
LUZ17_RS08625	COG3858	chitin binding
LUZ17_RS08640	COG0837	glucose binding
LUZ17_RS08645	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LUZ17_RS08655	COG0494	nUDIX hydrolase
LUZ17_RS08665	COG3956	TIGRFAM MazG family protein
LUZ17_RS08680	COG0330	HflC and HflK could
LUZ17_RS08695	COG0509	glycine decarboxylation via glycine cleavage system
LUZ17_RS08730	COG1960	acyl-CoA dehydrogenase activity
LUZ17_RS08740	COG1309	transcriptional regulator
LUZ17_RS08745	COG4771	TonB-dependent receptor
LUZ17_RS08755	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LUZ17_RS08765	COG0463	Glycosyl transferase, family 2
LUZ17_RS08790	COG1272	protein, Hemolysin III
LUZ17_RS08800	COG0739	heme binding
LUZ17_RS08805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LUZ17_RS08810	COG0626	cystathionine gamma-synthase activity
LUZ17_RS08820	COG1760	l-serine dehydratase
LUZ17_RS08835	COG2353	YceI-like domain
LUZ17_RS08845	COG2353	YceI-like domain
LUZ17_RS08915	COG1960	acyl-CoA dehydrogenase activity
LUZ17_RS08920	COG1024	Enoyl-CoA hydratase
LUZ17_RS08940	COG1250	3-hydroxyacyl-CoA dehydrogenase
LUZ17_RS08940	COG1024	Enoyl-CoA hydratase
LUZ17_RS08955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LUZ17_RS08985	COG1381	Involved in DNA repair and RecF pathway recombination
LUZ17_RS09000	COG2954	triphosphatase activity
LUZ17_RS09015	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LUZ17_RS09020	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
LUZ17_RS09025	COG3046	protein related to deoxyribodipyrimidine photolyase
LUZ17_RS09035	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LUZ17_RS09040	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LUZ17_RS09045	COG1278	Cold shock
LUZ17_RS09075	COG1201	RNA secondary structure unwinding
LUZ17_RS09080	COG1793	dna ligase
LUZ17_RS09090	COG1793	dna ligase
LUZ17_RS09090	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LUZ17_RS09120	COG0183	Belongs to the thiolase family
LUZ17_RS09160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LUZ17_RS09195	COG1047	Peptidyl-prolyl cis-trans
LUZ17_RS09210	COG2824	Alkylphosphonate utilization operon protein PhnA
LUZ17_RS09220	COG1902	pentaerythritol trinitrate reductase activity
LUZ17_RS09225	COG2814	Major facilitator Superfamily
LUZ17_RS09270	COG0392	lysyltransferase activity
LUZ17_RS09270	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LUZ17_RS09280	COG0251	oxidation-reduction process
LUZ17_RS09285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LUZ17_RS09300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LUZ17_RS09325	COG1595	DNA-templated transcription, initiation
LUZ17_RS09345	COG2878	Part of a membrane complex involved in electron transport
LUZ17_RS09355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LUZ17_RS09355	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LUZ17_RS09375	COG0833	amino acid
LUZ17_RS09380	COG2040	homocysteine
LUZ17_RS09395	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LUZ17_RS09430	COG2895	sulfate adenylyltransferase (ATP) activity
LUZ17_RS09430	COG0529	Catalyzes the synthesis of activated sulfate
LUZ17_RS09475	COG1981	membrane
LUZ17_RS09500	COG1131	(ABC) transporter
LUZ17_RS09505	COG4771	TonB-dependent receptor
LUZ17_RS09515	COG0825	malonyl-CoA metabolic process
LUZ17_RS09535	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LUZ17_RS09540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LUZ17_RS09560	COG0750	zinc metalloprotease
LUZ17_RS09570	COG0575	Belongs to the CDS family
LUZ17_RS09580	COG0233	cytoplasmic translational termination
LUZ17_RS09595	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LUZ17_RS09655	COG1393	Belongs to the ArsC family
LUZ17_RS09670	COG0367	asparagine synthase
LUZ17_RS09680	COG4774	siderophore transport
LUZ17_RS09715	COG1566	PFAM secretion protein HlyD family protein
LUZ17_RS09720	COG2814	Major facilitator Superfamily
LUZ17_RS09765	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LUZ17_RS09775	COG1960	acyl-CoA dehydrogenase activity
LUZ17_RS09800	COG2914	Belongs to the UPF0125 (RnfH) family
LUZ17_RS09805	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUZ17_RS09815	COG0497	DNA recombination
LUZ17_RS09825	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LUZ17_RS09830	COG0443	Heat shock 70 kDa protein
LUZ17_RS09835	COG0484	heat shock protein binding
LUZ17_RS09840	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LUZ17_RS09845	COG0287	Prephenate dehydrogenase
LUZ17_RS09845	COG1605	Chorismate mutase
LUZ17_RS09870	COG1132	(ABC) transporter
LUZ17_RS09905	COG2850	peptidyl-arginine hydroxylation
LUZ17_RS09980	COG1131	(ABC) transporter
LUZ17_RS09985	COG1725	Transcriptional regulator
LUZ17_RS09995	COG0386	Belongs to the glutathione peroxidase family
LUZ17_RS10010	COG2900	Belongs to the SlyX family
LUZ17_RS10025	COG1609	Transcriptional regulator
LUZ17_RS10035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUZ17_RS10045	COG1410	methionine synthase
LUZ17_RS10045	COG0646	methionine synthase
LUZ17_RS10050	COG0646	methionine synthase
LUZ17_RS10050	COG1410	methionine synthase
LUZ17_RS10055	COG2226	methyltransferase
LUZ17_RS10060	COG1960	acyl-CoA dehydrogenase activity
LUZ17_RS10085	COG0557	exoribonuclease II activity
LUZ17_RS10105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LUZ17_RS10115	COG3039	Transposase
LUZ17_RS10135	COG3328	transposase activity
LUZ17_RS10160	COG3039	Transposase
LUZ17_RS10210	COG3039	Transposase
LUZ17_RS10260	COG3039	Transposase
LUZ17_RS10270	COG0583	DNA-binding transcription factor activity
LUZ17_RS10320	COG2201	protein-glutamate methylesterase activity
LUZ17_RS10350	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LUZ17_RS10360	COG0531	amino acid
LUZ17_RS10365	COG0531	amino acid
LUZ17_RS10375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LUZ17_RS10380	COG0277	FAD linked oxidase domain protein
LUZ17_RS10445	COG0436	Aminotransferase
LUZ17_RS10470	COG1187	pseudouridine synthase activity
LUZ17_RS10475	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LUZ17_RS10480	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LUZ17_RS10485	COG2350	Protein conserved in bacteria
LUZ17_RS10515	COG1175	transmembrane transport
LUZ17_RS10520	COG0395	ABC-type sugar transport system, permease component
LUZ17_RS10545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LUZ17_RS10555	COG2957	Belongs to the agmatine deiminase family
LUZ17_RS10570	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LUZ17_RS10575	COG0539	negative regulation of cytoplasmic translation
LUZ17_RS10580	COG0776	regulation of translation
LUZ17_RS10590	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LUZ17_RS10595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LUZ17_RS10605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LUZ17_RS10625	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LUZ17_RS10640	COG3002	Belongs to the UPF0753 family
LUZ17_RS10645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LUZ17_RS10650	COG0583	DNA-binding transcription factor activity
LUZ17_RS10665	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_RS10680	COG0583	DNA-binding transcription factor activity
LUZ17_RS10705	COG1914	H( )-stimulated, divalent metal cation uptake system
LUZ17_RS10725	COG0668	transmembrane transport
LUZ17_RS10775	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_RS10780	COG1183	phosphatidylcholine synthase activity
LUZ17_RS10790	COG3243	poly(R)-hydroxyalkanoic acid synthase
LUZ17_RS10805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUZ17_RS10805	COG0723	plastoquinol--plastocyanin reductase activity
LUZ17_RS10815	COG2183	response to ionizing radiation
LUZ17_RS10830	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LUZ17_RS10845	COG0671	phosphoesterase, PA-phosphatase related
LUZ17_RS10870	COG0697	spore germination
LUZ17_RS10900	COG1012	belongs to the aldehyde dehydrogenase family
LUZ17_RS10935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LUZ17_RS10950	COG0124	histidyl-tRNA synthetase
LUZ17_RS10970	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LUZ17_RS10985	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LUZ17_RS10985	COG0131	Imidazoleglycerol-phosphate dehydratase
LUZ17_RS10995	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LUZ17_RS11005	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LUZ17_RS11005	COG0140	phosphoribosyl-ATP diphosphatase activity
LUZ17_RS11235	COG2201	protein-glutamate methylesterase activity
LUZ17_RS11260	COG3039	Transposase
LUZ17_RS11280	COG3328	transposase activity
LUZ17_RS11315	COG0322	excinuclease ABC activity
LUZ17_RS11325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LUZ17_RS11335	COG1663	tetraacyldisaccharide 4'-kinase activity
LUZ17_RS11350	COG0811	peptide transport
LUZ17_RS11375	COG4591	ABC-type transport system involved in lipoprotein release permease component
LUZ17_RS11390	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LUZ17_RS11405	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LUZ17_RS11420	COG0354	folic acid binding
LUZ17_RS11435	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LUZ17_RS11445	COG0363	glucosamine-6-phosphate deaminase activity
LUZ17_RS11450	COG0129	dihydroxy-acid dehydratase activity
LUZ17_RS11455	COG0800	Aldolase
LUZ17_RS11485	COG0784	Response regulator, receiver
LUZ17_RS11485	COG2205	protein histidine kinase activity
LUZ17_RS11485	COG5002	protein histidine kinase activity
LUZ17_RS11565	COG0386	Belongs to the glutathione peroxidase family
LUZ17_RS11650	COG2203	Gaf domain
LUZ17_RS11650	COG3706	GGDEF domain
LUZ17_RS11650	COG4251	negative regulation of phosphorylation
LUZ17_RS11650	COG5001	Diguanylate cyclase
LUZ17_RS11665	COG1472	Belongs to the glycosyl hydrolase 3 family
LUZ17_RS11695	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LUZ17_RS11710	COG0617	tRNA 3'-terminal CCA addition
LUZ17_RS11720	COG1469	GTP cyclohydrolase I activity
LUZ17_RS11725	COG0860	N-Acetylmuramoyl-L-alanine amidase
LUZ17_RS11770	COG4566	intracellular signal transduction
LUZ17_RS11800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LUZ17_RS11805	COG0077	Prephenate dehydratase
LUZ17_RS11805	COG1605	Chorismate mutase
LUZ17_RS11815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LUZ17_RS11855	COG1228	amidohydrolase
LUZ17_RS11860	COG2986	histidine ammonia-lyase
LUZ17_RS11870	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LUZ17_RS11895	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LUZ17_RS11910	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LUZ17_RS11930	COG3115	cell septum assembly
LUZ17_RS11940	COG0359	binds to the 23S rRNA
LUZ17_RS11950	COG0360	Binds together with S18 to 16S ribosomal RNA
LUZ17_RS11955	COG0316	Belongs to the HesB IscA family
LUZ17_RS11985	COG0288	reversible hydration of carbon dioxide
LUZ17_RS12010	COG2925	Exonuclease
LUZ17_RS12020	COG0667	Aldo Keto reductase
LUZ17_RS12045	COG0116	Belongs to the methyltransferase superfamily
LUZ17_RS12045	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LUZ17_RS12090	COG0494	nUDIX hydrolase
LUZ17_RS12105	COG1024	Enoyl-CoA hydratase
LUZ17_RS12115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LUZ17_RS12135	COG3039	Transposase
LUZ17_RS12175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LUZ17_RS12180	COG0573	inorganic phosphate transmembrane transporter activity
LUZ17_RS12195	COG0704	Plays a role in the regulation of phosphate uptake
LUZ17_RS12205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LUZ17_RS12220	COG3328	transposase activity
LUZ17_RS12240	COG3039	Transposase
LUZ17_RS12250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LUZ17_RS12255	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LUZ17_RS12260	COG1862	Preprotein translocase
LUZ17_RS12265	COG0343	queuine tRNA-ribosyltransferase activity
LUZ17_RS12340	COG0405	Gamma-glutamyltransferase
LUZ17_RS12345	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LUZ17_RS12355	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LUZ17_RS12360	COG0742	ribosomal rna small subunit methyltransferase
LUZ17_RS12380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LUZ17_RS12415	COG3039	Transposase
LUZ17_RS12445	COG0303	'Molybdopterin
LUZ17_RS12455	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUZ17_RS12465	COG1426	Protein conserved in bacteria
LUZ17_RS12475	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LUZ17_RS12490	COG1024	Enoyl-CoA hydratase
LUZ17_RS12490	COG1250	3-hydroxyacyl-CoA dehydrogenase
LUZ17_RS12495	COG0183	Belongs to the thiolase family
LUZ17_RS12500	COG0038	chloride channel
LUZ17_RS12520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LUZ17_RS12540	COG1674	ftsk spoiiie
LUZ17_RS12545	COG0492	ferredoxin-NADP+ reductase activity
LUZ17_RS12580	COG0542	response to heat
LUZ17_RS12595	COG0482	sulfurtransferase activity
LUZ17_RS12620	COG5001	Diguanylate cyclase
LUZ17_RS12625	COG4585	Histidine kinase
LUZ17_RS12635	COG5002	protein histidine kinase activity
LUZ17_RS12655	COG0835	chemotaxis
LUZ17_RS12655	COG0784	Response regulator, receiver
LUZ17_RS12665	COG1558	bacterial-type flagellum-dependent cell motility
LUZ17_RS12670	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LUZ17_RS12680	COG4787	bacterial-type flagellum-dependent cell motility
LUZ17_RS12715	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LUZ17_RS12720	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LUZ17_RS12755	COG2201	protein-glutamate methylesterase activity
LUZ17_RS12775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LUZ17_RS12785	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_RS12815	COG1677	Flagellar hook-basal body complex protein FliE
LUZ17_RS12865	COG3190	flagellar
LUZ17_RS12880	COG1684	flagellar biosynthetic protein fliR
LUZ17_RS12935	COG2198	Histidine kinase
LUZ17_RS12935	COG0784	Response regulator, receiver
LUZ17_RS12935	COG0643	Histidine kinase
LUZ17_RS12965	COG3039	Transposase
LUZ17_RS12975	COG3209	COG3209 Rhs family protein
LUZ17_RS12985	COG3039	Transposase
LUZ17_RS12995	COG3039	Transposase
LUZ17_RS13005	COG3039	Transposase
LUZ17_RS13085	COG3039	Transposase
LUZ17_RS13095	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LUZ17_RS13100	COG4988	ABC transporter
LUZ17_RS13115	COG3039	Transposase
LUZ17_RS13150	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LUZ17_RS13170	COG0165	Argininosuccinate lyase
LUZ17_RS13185	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LUZ17_RS13190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LUZ17_RS13200	COG0137	argininosuccinate synthase activity
LUZ17_RS13205	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LUZ17_RS13220	COG2166	iron-sulfur cluster assembly
LUZ17_RS13245	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LUZ17_RS13280	COG3039	Transposase
LUZ17_RS13290	COG4677	pectinesterase activity
LUZ17_RS13315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LUZ17_RS13320	COG0402	S-adenosylhomocysteine deaminase activity
LUZ17_RS13335	COG1509	lysine 2,3-aminomutase activity
LUZ17_RS13340	COG3300	MHYT domain
LUZ17_RS13340	COG5001	Diguanylate cyclase
LUZ17_RS13355	COG0483	inositol monophosphate 1-phosphatase activity
LUZ17_RS13360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LUZ17_RS13380	COG0488	(ABC) transporter
LUZ17_RS13385	COG0513	Belongs to the DEAD box helicase family
LUZ17_RS13405	COG0625	glutathione transferase activity
LUZ17_RS13415	COG1671	Belongs to the UPF0178 family
LUZ17_RS13420	COG4681	YaeQ
LUZ17_RS13425	COG2081	HI0933 family
LUZ17_RS13445	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_RS13465	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LUZ17_RS13470	COG0860	N-Acetylmuramoyl-L-alanine amidase
LUZ17_RS13475	COG0802	atpase or kinase
LUZ17_RS13480	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LUZ17_RS13480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LUZ17_RS13485	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LUZ17_RS13510	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LUZ17_RS13575	COG3328	transposase activity
LUZ17_RS13585	COG2094	Belongs to the DNA glycosylase MPG family
LUZ17_RS13610	COG2969	positive regulation of protein catabolic process
LUZ17_RS13615	COG0625	glutathione transferase activity
LUZ17_RS13620	COG2857	Cytochrome c1
LUZ17_RS13625	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LUZ17_RS13630	COG0723	plastoquinol--plastocyanin reductase activity
LUZ17_RS13635	COG0741	lytic transglycosylase activity
LUZ17_RS13665	COG1702	phosphate starvation-inducible protein PhoH
LUZ17_RS13685	COG4535	Mg2 and Co2 transporter CorC
LUZ17_RS13700	COG1012	belongs to the aldehyde dehydrogenase family
LUZ17_RS13720	COG3842	ATPase activity
LUZ17_RS13755	COG0174	glutamine synthetase
LUZ17_RS13760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUZ17_RS13770	COG0477	Major facilitator Superfamily
LUZ17_RS13780	COG0243	molybdopterin cofactor binding
LUZ17_RS13790	COG2223	nitrite transmembrane transporter activity
LUZ17_RS13795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LUZ17_RS13800	COG1121	(ABC) transporter
LUZ17_RS13810	COG2733	membrane
LUZ17_RS13815	COG5002	protein histidine kinase activity
LUZ17_RS13815	COG2205	protein histidine kinase activity
LUZ17_RS13815	COG0784	Response regulator, receiver
LUZ17_RS13825	COG3039	Transposase
LUZ17_RS13830	COG2902	Dehydrogenase
LUZ17_RS13840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUZ17_RS13845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LUZ17_RS13865	COG1609	Transcriptional regulator
LUZ17_RS13870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LUZ17_RS13870	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUZ17_RS13875	COG1105	Belongs to the carbohydrate kinase PfkB family
LUZ17_RS13880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LUZ17_RS13880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LUZ17_RS13890	COG3039	Transposase
LUZ17_RS13970	COG3501	Rhs element vgr protein
LUZ17_RS13970	COG3409	Peptidoglycan-binding domain 1 protein
LUZ17_RS13990	COG3501	Rhs element vgr protein
LUZ17_RS13990	COG3409	Peptidoglycan-binding domain 1 protein
LUZ17_RS14035	COG3039	Transposase
LUZ17_RS14060	COG4771	TonB-dependent receptor
LUZ17_RS14070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LUZ17_RS14090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LUZ17_RS14095	COG1360	Flagellar Motor Protein
LUZ17_RS14105	COG0835	chemotaxis
LUZ17_RS14115	COG0745	RESPONSE REGULATOR receiver
LUZ17_RS14145	COG0840	transmembrane signaling receptor activity
LUZ17_RS14155	COG0840	transmembrane signaling receptor activity
LUZ17_RS14165	COG0840	transmembrane signaling receptor activity
LUZ17_RS14175	COG0840	transmembrane signaling receptor activity
LUZ17_RS14180	COG0840	transmembrane signaling receptor activity
LUZ17_RS14195	COG0835	chemotaxis
LUZ17_RS14215	COG0840	transmembrane signaling receptor activity
LUZ17_RS14245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LUZ17_RS14275	COG0318	PFAM AMP-dependent synthetase and ligase
LUZ17_RS14280	COG1024	Enoyl-CoA hydratase
LUZ17_RS14285	COG2198	Histidine kinase
LUZ17_RS14285	COG2205	protein histidine kinase activity
LUZ17_RS14285	COG0784	Response regulator, receiver
LUZ17_RS14335	COG3039	Transposase
LUZ17_RS14345	COG3039	Transposase
LUZ17_RS14355	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LUZ17_RS14365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LUZ17_RS14370	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LUZ17_RS14380	COG0505	Belongs to the CarA family
LUZ17_RS14385	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LUZ17_RS14395	COG2258	MOSC domain
LUZ17_RS14400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUZ17_RS14445	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LUZ17_RS14465	COG0477	Major facilitator Superfamily
LUZ17_RS14475	COG1070	Carbohydrate kinase
LUZ17_RS14485	COG1501	Belongs to the glycosyl hydrolase 31 family
LUZ17_RS14500	COG0800	Aldolase
LUZ17_RS14505	COG4948	Mandelate Racemase Muconate Lactonizing
LUZ17_RS14515	COG3734	2-keto-3-deoxy-galactonokinase
LUZ17_RS14520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LUZ17_RS14530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LUZ17_RS14545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LUZ17_RS14550	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LUZ17_RS14560	COG0351	phosphomethylpyrimidine kinase
LUZ17_RS14585	COG0583	DNA-binding transcription factor activity
LUZ17_RS14590	COG1741	Belongs to the pirin family
LUZ17_RS14605	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LUZ17_RS14610	COG0305	Participates in initiation and elongation during chromosome replication
LUZ17_RS14630	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LUZ17_RS14635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LUZ17_RS14640	COG2137	regulation of response to DNA damage stimulus
LUZ17_RS14645	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LUZ17_RS14660	COG1546	Belongs to the CinA family
LUZ17_RS14665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LUZ17_RS14680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LUZ17_RS14690	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LUZ17_RS14695	COG1534	Rna-binding protein
LUZ17_RS14710	COG1238	metal cluster binding
LUZ17_RS14715	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LUZ17_RS14720	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LUZ17_RS14725	COG2840	Smr protein MutS2
LUZ17_RS14735	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LUZ17_RS14750	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LUZ17_RS14755	COG0148	phosphopyruvate hydratase activity
LUZ17_RS14765	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LUZ17_RS14770	COG0504	CTP synthase activity
LUZ17_RS14795	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LUZ17_RS14800	COG0306	phosphate transporter
LUZ17_RS14810	COG1253	flavin adenine dinucleotide binding
LUZ17_RS14825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUZ17_RS14835	COG0477	Major facilitator Superfamily
LUZ17_RS14845	COG1132	(ABC) transporter
LUZ17_RS14850	COG1136	(ABC) transporter
LUZ17_RS14870	COG0438	transferase activity, transferring glycosyl groups
LUZ17_RS14880	COG2264	protein methyltransferase activity
LUZ17_RS14910	COG2244	polysaccharide biosynthetic process
LUZ17_RS14960	COG1595	DNA-templated transcription, initiation
LUZ17_RS14975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LUZ17_RS14995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LUZ17_RS15040	COG2201	protein-glutamate methylesterase activity
LUZ17_RS15060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LUZ17_RS15065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUZ17_RS15120	COG1858	cytochrome C peroxidase
LUZ17_RS15155	COG0515	serine threonine protein kinase
LUZ17_RS15160	COG0631	protein serine/threonine phosphatase activity
LUZ17_RS15265	COG3039	Transposase
LUZ17_RS15315	COG0316	Belongs to the HesB IscA family
LUZ17_RS15315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LUZ17_RS15320	COG2154	pterin-4-alpha-carbinolamine dehydratase
LUZ17_RS15335	COG3064	Membrane
LUZ17_RS15345	COG1530	ribonuclease E activity
LUZ17_RS15360	COG1054	Belongs to the UPF0176 family
LUZ17_RS15365	COG3039	Transposase
LUZ17_RS15385	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LUZ17_RS15420	COG3039	Transposase
LUZ17_RS15430	COG3039	Transposase
LUZ17_RS15460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LUZ17_RS15460	COG1648	precorrin-2 dehydrogenase activity
LUZ17_RS15485	COG0746	molybdenum cofactor guanylyltransferase activity
LUZ17_RS15575	COG4206	TonB-dependent receptor
LUZ17_RS15605	COG0531	amino acid
LUZ17_RS15620	COG0006	proline dipeptidase activity
LUZ17_RS15630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LUZ17_RS15645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUZ17_RS15650	COG3938	Belongs to the proline racemase family
LUZ17_RS15660	COG0552	protein localization to endoplasmic reticulum
LUZ17_RS15680	COG0784	Response regulator, receiver
LUZ17_RS15680	COG4191	Histidine kinase
LUZ17_RS15685	COG3039	Transposase
LUZ17_RS15770	COG3040	lipid binding
LUZ17_RS15810	COG0438	transferase activity, transferring glycosyl groups
LUZ17_RS15820	COG0438	transferase activity, transferring glycosyl groups
LUZ17_RS15825	COG0438	transferase activity, transferring glycosyl groups
LUZ17_RS15895	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LUZ17_RS15930	COG0556	nucleotide-excision repair
LUZ17_RS15935	COG4969	Belongs to the N-Me-Phe pilin family
LUZ17_RS15975	COG1611	Belongs to the LOG family
LUZ17_RS15990	COG2095	MarC family integral membrane protein
LUZ17_RS16000	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LUZ17_RS16035	COG1185	polyribonucleotide nucleotidyltransferase activity
LUZ17_RS16040	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LUZ17_RS16060	COG0195	Participates in both transcription termination and antitermination
LUZ17_RS16065	COG0779	Required for maturation of 30S ribosomal subunits
LUZ17_RS16075	COG1007	ATP synthesis coupled electron transport
LUZ17_RS16105	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LUZ17_RS16110	COG1034	ATP synthesis coupled electron transport
LUZ17_RS16115	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LUZ17_RS16120	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LUZ17_RS16125	COG0649	NAD binding
LUZ17_RS16130	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LUZ17_RS16140	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LUZ17_RS16155	COG0149	triose-phosphate isomerase activity
LUZ17_RS16200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LUZ17_RS16205	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LUZ17_RS16230	COG0135	phosphoribosylanthranilate isomerase activity
LUZ17_RS16235	COG0101	tRNA pseudouridine synthase activity
LUZ17_RS16255	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LUZ17_RS16260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LUZ17_RS16265	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LUZ17_RS16270	COG2890	protein-(glutamine-N5) methyltransferase activity
LUZ17_RS16310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LUZ17_RS16340	COG0717	Belongs to the dCTP deaminase family
LUZ17_RS16345	COG0489	protein tyrosine kinase activity
LUZ17_RS16385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUZ17_RS16390	COG2311	Membrane
LUZ17_RS16395	COG1047	Peptidyl-prolyl cis-trans
LUZ17_RS16400	COG0791	NLP P60 protein
LUZ17_RS16405	COG0791	NLP P60 protein
LUZ17_RS16430	COG1785	Belongs to the alkaline phosphatase family
LUZ17_RS16435	COG0037	tRNA processing
LUZ17_RS16440	COG1722	exodeoxyribonuclease VII activity
LUZ17_RS16445	COG0142	geranyltranstransferase activity
LUZ17_RS16470	COG0312	modulator of DNA gyrase
LUZ17_RS16475	COG3028	Belongs to the UPF0307 family
LUZ17_RS16480	COG0312	modulator of DNA gyrase
LUZ17_RS16490	COG3164	Protein of unknown function
LUZ17_RS16505	COG2968	Membrane
LUZ17_RS16530	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LUZ17_RS16555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LUZ17_RS16580	COG3118	belongs to the thioredoxin family
LUZ17_RS16645	COG3039	Transposase
LUZ17_RS16650	COG3039	Transposase
LUZ17_RS16735	COG2022	thiamine diphosphate biosynthetic process
LUZ17_RS16745	COG0471	metal ion transport
LUZ17_RS16745	COG3273	potassium ion transport
LUZ17_RS16765	COG3039	Transposase
LUZ17_RS16780	COG1970	mechanosensitive ion channel activity
LUZ17_RS16800	COG2272	Belongs to the type-B carboxylesterase lipase family
LUZ17_RS16805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LUZ17_RS16825	COG0308	aminopeptidase N
LUZ17_RS16830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LUZ17_RS16840	COG0529	Catalyzes the synthesis of activated sulfate
LUZ17_RS16840	COG2895	sulfate adenylyltransferase (ATP) activity
LUZ17_RS16845	COG0175	sulfate reduction
LUZ17_RS16850	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LUZ17_RS16855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LUZ17_RS16860	COG0175	sulfate reduction
LUZ17_RS16880	COG0784	Response regulator, receiver
LUZ17_RS16880	COG2198	Histidine kinase
LUZ17_RS16880	COG2205	protein histidine kinase activity
LUZ17_RS16930	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LUZ17_RS16935	COG3588	fructose-bisphosphate aldolase
LUZ17_RS16940	COG0469	pyruvate kinase activity
LUZ17_RS16980	COG0753	catalase activity
LUZ17_RS17000	COG3039	Transposase
LUZ17_RS17025	COG2207	Transcriptional regulator
LUZ17_RS17025	COG1917	Cupin 2, conserved barrel domain protein
LUZ17_RS17045	COG1506	peptidase
LUZ17_RS17045	COG0823	Involved in the tonB-independent uptake of proteins
LUZ17_RS17065	COG3039	Transposase
LUZ17_RS17070	COG1297	OPT oligopeptide transporter protein
LUZ17_RS17165	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LUZ17_RS17180	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
LUZ17_RS17185	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
LUZ17_RS17190	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LUZ17_RS17210	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LUZ17_RS17225	COG0732	type I restriction modification DNA specificity domain
LUZ17_RS17410	COG3179	chitinase
LUZ17_RS17465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LUZ17_RS17530	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LUZ17_RS17540	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LUZ17_RS17635	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LUZ17_RS17660	COG2197	response regulator
LUZ17_RS17665	COG4585	Histidine kinase
LUZ17_RS17680	COG2894	cell division
LUZ17_RS17685	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LUZ17_RS17695	COG0642	Histidine kinase
LUZ17_RS17700	COG0745	RESPONSE REGULATOR receiver
LUZ17_RS17705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LUZ17_RS17715	COG2194	sulfuric ester hydrolase activity
LUZ17_RS17745	COG3551	Protein conserved in bacteria
LUZ17_RS17805	COG0203	ribosomal protein L17
LUZ17_RS17815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LUZ17_RS17820	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LUZ17_RS17830	COG0201	protein transport
LUZ17_RS17840	COG1841	ribosomal large subunit assembly
LUZ17_RS17870	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LUZ17_RS17880	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LUZ17_RS17885	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LUZ17_RS17890	COG0255	Belongs to the universal ribosomal protein uL29 family
LUZ17_RS17895	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LUZ17_RS17905	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LUZ17_RS17920	COG0089	rRNA binding
LUZ17_RS17925	COG0088	Forms part of the polypeptide exit tunnel
LUZ17_RS17930	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LUZ17_RS17935	COG0051	transcription antitermination factor activity, RNA binding
LUZ17_RS17955	COG0049	tRNA binding
LUZ17_RS17960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LUZ17_RS17965	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LUZ17_RS17970	COG0085	RNA polymerase activity
LUZ17_RS17975	COG0222	ribosome binding
LUZ17_RS17980	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LUZ17_RS17990	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LUZ17_RS17995	COG0250	Participates in transcription elongation, termination and antitermination
LUZ17_RS18000	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LUZ17_RS18030	COG0012	GTP binding
LUZ17_RS18035	COG0193	aminoacyl-tRNA hydrolase activity
LUZ17_RS18045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LUZ17_RS18060	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LUZ17_RS18075	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LUZ17_RS18085	COG0521	Mo-molybdopterin cofactor biosynthetic process
LUZ17_RS18105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LUZ17_RS18110	COG1295	ribonuclease BN
LUZ17_RS18140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LUZ17_RS18150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LUZ17_RS18175	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LUZ17_RS18200	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LUZ17_RS18215	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LUZ17_RS18215	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LUZ17_RS18265	COG2890	protein-(glutamine-N5) methyltransferase activity
LUZ17_RS18275	COG3634	alkyl hydroperoxide reductase activity
LUZ17_RS18280	COG0583	DNA-binding transcription factor activity
LUZ17_RS18285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LUZ17_RS18350	COG4783	chaperone-mediated protein folding
LUZ17_RS18365	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LUZ17_RS18375	COG0438	transferase activity, transferring glycosyl groups
LUZ17_RS18380	COG0671	phosphoesterase, PA-phosphatase related
LUZ17_RS18385	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LUZ17_RS18405	COG2833	Protein of unknown function (DUF455)
LUZ17_RS18425	COG0285	dihydrofolate synthase activity
LUZ17_RS18435	COG0406	alpha-ribazole phosphatase activity
LUZ17_RS18465	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LUZ17_RS18470	COG4208	sulfate ABC transporter
LUZ17_RS18475	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LUZ17_RS18480	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LUZ17_RS18485	COG0156	8-amino-7-oxononanoate synthase activity
LUZ17_RS18510	COG0604	alcohol dehydrogenase
LUZ17_RS18515	COG0446	pyridine nucleotide-disulphide oxidoreductase
LUZ17_RS18515	COG1902	pentaerythritol trinitrate reductase activity
LUZ17_RS18650	COG3386	PFAM SMP-30 Gluconolaconase
LUZ17_RS18670	COG1024	Enoyl-CoA hydratase
LUZ17_RS18680	COG0318	PFAM AMP-dependent synthetase and ligase
LUZ17_RS18685	COG0583	DNA-binding transcription factor activity
LUZ17_RS18725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUZ17_RS18730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUZ17_RS18740	COG2096	Adenosyltransferase
LUZ17_RS18745	COG0123	including yeast histone deacetylase and acetoin utilization protein
LUZ17_RS18760	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LUZ17_RS18770	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LUZ17_RS18775	COG2967	ApaG domain
LUZ17_RS18800	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LUZ17_RS18820	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LUZ17_RS18835	COG0642	Histidine kinase
LUZ17_RS18850	COG4181	ATPase activity
LUZ17_RS18860	COG2175	clavaminate synthase activity
LUZ17_RS18910	COG0667	Aldo Keto reductase
LUZ17_RS18920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LUZ17_RS18925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUZ17_RS18935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LUZ17_RS18950	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LUZ17_RS18990	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LUZ17_RS19045	COG3321	synthase
LUZ17_RS19045	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_RS19045	COG0604	alcohol dehydrogenase
LUZ17_RS19055	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LUZ17_RS19075	COG0494	nUDIX hydrolase
LUZ17_RS19090	COG4942	peptidase
LUZ17_RS19090	COG1388	LysM domain
LUZ17_RS19100	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LUZ17_RS19115	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LUZ17_RS19120	COG1181	Belongs to the D-alanine--D-alanine ligase family
LUZ17_RS19125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LUZ17_RS19145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LUZ17_RS19160	COG3116	cell division
LUZ17_RS19165	COG0275	rRNA processing
LUZ17_RS19200	COG0792	nuclease activity
LUZ17_RS19205	COG1988	membrane-bound metal-dependent
LUZ17_RS19210	COG0277	FAD linked oxidase domain protein
LUZ17_RS19215	COG0745	RESPONSE REGULATOR receiver
LUZ17_RS19220	COG2205	protein histidine kinase activity
LUZ17_RS19230	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LUZ17_RS19235	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LUZ17_RS19255	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LUZ17_RS19260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LUZ17_RS19265	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LUZ17_RS19285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LUZ17_RS19285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LUZ17_RS19305	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LUZ17_RS19325	COG0488	(ABC) transporter
LUZ17_RS19350	COG3791	Glutathione-dependent formaldehyde-activating
LUZ17_RS19375	COG2205	protein histidine kinase activity
LUZ17_RS19430	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LUZ17_RS19465	COG3039	Transposase
LUZ17_RS19470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LUZ17_RS19480	COG3039	Transposase
LUZ17_RS19535	COG3039	Transposase
LUZ17_RS19585	COG1649	PFAM Uncharacterised BCR, COG1649
LUZ17_RS19585	COG0726	polysaccharide deacetylase
LUZ17_RS19590	COG1215	transferase activity, transferring glycosyl groups
LUZ17_RS19600	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LUZ17_RS19605	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LUZ17_RS19610	COG1609	Transcriptional regulator
LUZ17_RS19620	COG2188	Transcriptional regulator
LUZ17_RS19635	COG3250	beta-galactosidase activity
LUZ17_RS19675	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LUZ17_RS19680	COG4191	Histidine kinase
LUZ17_RS19685	COG0784	Response regulator, receiver
LUZ17_RS19690	COG4251	negative regulation of phosphorylation
LUZ17_RS19695	COG2823	Periplasmic or secreted lipoprotein
LUZ17_RS19700	COG0673	inositol 2-dehydrogenase activity
LUZ17_RS19705	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LUZ17_RS19740	COG1051	belongs to the nudix hydrolase family
LUZ17_RS19740	COG1056	cytidyltransferase-related domain
LUZ17_RS19780	COG2921	Belongs to the UPF0250 family
LUZ17_RS19795	COG1686	Belongs to the peptidase S11 family
LUZ17_RS19800	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LUZ17_RS19805	COG2951	lytic endotransglycosylase activity
LUZ17_RS19875	COG0772	Belongs to the SEDS family
LUZ17_RS19890	COG1792	Involved in formation and maintenance of cell shape
LUZ17_RS19895	COG1077	Cell shape determining protein MreB Mrl
LUZ17_RS19900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUZ17_RS19905	COG3039	Transposase
LUZ17_RS19955	COG2199	diguanylate cyclase activity
LUZ17_RS19960	COG0308	aminopeptidase N
LUZ17_RS19990	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LUZ17_RS20020	COG0436	Aminotransferase
LUZ17_RS20035	COG1505	serine-type exopeptidase activity
LUZ17_RS20060	COG0181	hydroxymethylbilane synthase activity
LUZ17_RS20070	COG3275	phosphorelay sensor kinase activity
LUZ17_RS20105	COG0659	secondary active sulfate transmembrane transporter activity
LUZ17_RS20110	COG5297	Belongs to the glycosyl hydrolase family 6
LUZ17_RS20110	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LUZ17_RS20180	COG0598	Magnesium transport protein CorA
LUZ17_RS20190	COG1113	amino acid transport
LUZ17_RS20200	COG5297	Belongs to the glycosyl hydrolase family 6
LUZ17_RS20205	COG4305	rare lipoprotein A
LUZ17_RS20210	COG0697	spore germination
LUZ17_RS20270	COG4221	oxidoreductase activity
LUZ17_RS20300	COG0456	acetyltransferase
LUZ17_RS20310	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LUZ17_RS20340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LUZ17_RS20340	COG2111	Na H antiporter
LUZ17_RS20345	COG1006	Multisubunit Na H antiporter MnhC subunit
LUZ17_RS20350	COG0651	ATP synthesis coupled electron transport
LUZ17_RS20360	COG2212	antiporter activity
LUZ17_RS20365	COG1320	monovalent cation:proton antiporter activity
LUZ17_RS20375	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LUZ17_RS20395	COG3104	oligopeptide transport
LUZ17_RS20400	COG3483	tryptophan 2,3-dioxygenase activity
LUZ17_RS20445	COG0183	Belongs to the thiolase family
LUZ17_RS20495	COG3039	Transposase
LUZ17_RS20525	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LUZ17_RS20530	COG3023	N-Acetylmuramoyl-L-alanine amidase
LUZ17_RS20540	COG4948	Mandelate Racemase Muconate Lactonizing
LUZ17_RS20575	COG0531	amino acid
LUZ17_RS20610	COG4682	membrane
LUZ17_RS20615	COG2133	pyrroloquinoline quinone binding
LUZ17_RS20650	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LUZ17_RS20655	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LUZ17_RS20665	COG1610	YqeY-like protein
LUZ17_RS20675	COG1295	ribonuclease BN
LUZ17_RS20680	COG0358	DNA primase activity
LUZ17_RS20745	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LUZ17_RS20760	COG1565	acr, cog1565
LUZ17_RS20760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LUZ17_RS20810	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LUZ17_RS20815	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LUZ17_RS20820	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
LUZ17_RS20830	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LUZ17_RS20835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LUZ17_RS20850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LUZ17_RS20910	COG3328	transposase activity
LUZ17_RS20920	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LUZ17_RS20920	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LUZ17_RS20930	COG1473	amidohydrolase
LUZ17_RS20935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUZ17_RS20940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LUZ17_RS20950	COG5383	Protein conserved in bacteria
LUZ17_RS20985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LUZ17_RS20990	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LUZ17_RS21005	COG0028	Belongs to the TPP enzyme family
LUZ17_RS21010	COG4191	Histidine kinase
LUZ17_RS21035	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LUZ17_RS21050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LUZ17_RS21055	COG3177	Filamentation induced by cAMP protein fic
LUZ17_RS21070	COG0596	Alpha beta hydrolase
LUZ17_RS21075	COG0727	PFAM Uncharacterised protein family (UPF0153)
LUZ17_RS21080	COG0318	PFAM AMP-dependent synthetase and ligase
LUZ17_RS21085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LUZ17_RS21135	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LUZ17_RS21145	COG0129	dihydroxy-acid dehydratase activity
LUZ17_RS21170	COG3039	Transposase
LUZ17_RS21180	COG0408	coproporphyrinogen oxidase activity
LUZ17_RS21270	COG2353	YceI-like domain
LUZ17_RS21300	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LUZ17_RS21315	COG3386	PFAM SMP-30 Gluconolaconase
LUZ17_RS21345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LUZ17_RS21365	COG0459	protein refolding
LUZ17_RS21390	COG1252	NADH dehydrogenase
LUZ17_RS21400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LUZ17_RS21405	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LUZ17_RS21410	COG2201	protein-glutamate methylesterase activity
LUZ17_RS21415	COG2177	Part of the ABC transporter FtsEX involved in
LUZ17_RS21420	COG2884	Cell division ATP-binding protein ftsE
LUZ17_RS21430	COG3118	belongs to the thioredoxin family
LUZ17_RS21435	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LUZ17_RS21450	COG0729	surface antigen
LUZ17_RS21455	COG2911	Protein conserved in bacteria
LUZ17_RS21505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LUZ17_RS21560	COG1733	regulation of RNA biosynthetic process
LUZ17_RS21565	COG0702	epimerase
LUZ17_RS21595	COG0583	DNA-binding transcription factor activity
LUZ17_RS21600	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LUZ17_RS21620	COG0745	RESPONSE REGULATOR receiver
LUZ17_RS21650	COG1902	pentaerythritol trinitrate reductase activity
LUZ17_RS21655	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LUZ17_RS21665	COG2814	Major facilitator Superfamily
LUZ17_RS21670	COG0583	DNA-binding transcription factor activity
LUZ17_RS21685	COG0084	hydrolase, TatD family'
LUZ17_RS21735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LUZ17_RS21810	COG4770	biotin carboxylase activity
LUZ17_RS21815	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LUZ17_RS21820	COG1960	acyl-CoA dehydrogenase activity
LUZ17_RS21875	COG0523	cobalamin synthesis protein
LUZ17_RS21895	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LUZ17_RS21910	COG4771	TonB-dependent receptor
LUZ17_RS21915	COG0457	Tetratricopeptide repeat
LUZ17_RS21930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LUZ17_RS21945	COG0519	Catalyzes the synthesis of GMP from XMP
LUZ17_RS21945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LUZ17_RS21955	COG0805	protein transport
LUZ17_RS21965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LUZ17_RS21975	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LUZ17_RS22025	COG3661	Belongs to the glycosyl hydrolase 67 family
LUZ17_RS22035	COG4948	Mandelate Racemase Muconate Lactonizing
LUZ17_RS22045	COG1472	Belongs to the glycosyl hydrolase 3 family
LUZ17_RS22050	COG0246	Mannitol dehydrogenase
LUZ17_RS22075	COG3693	PFAM glycoside hydrolase, family 10
LUZ17_RS22100	COG2211	Major facilitator Superfamily
LUZ17_RS22195	COG1846	Transcriptional regulator
LUZ17_RS22200	COG1764	response to oxidative stress
LUZ17_RS22285	COG3549	Plasmid maintenance system killer
LUZ17_RS22295	COG1074	ATP-dependent DNA helicase activity
LUZ17_RS22300	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LUZ17_RS22315	COG1196	nuclear chromosome segregation
LUZ17_RS22350	COG2032	superoxide dismutase activity
LUZ17_RS22355	COG2032	superoxide dismutase activity
LUZ17_RS22360	COG2204	response regulator
LUZ17_RS22365	COG3852	Histidine kinase
LUZ17_RS22370	COG0004	ammonium transporteR
LUZ17_RS22375	COG0347	Belongs to the P(II) protein family
LUZ17_RS22380	COG0174	glutamine synthetase
LUZ17_RS22385	COG1968	undecaprenyl-diphosphatase activity
LUZ17_RS22425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LUZ17_RS22435	COG2062	phosphohistidine phosphatase, SixA
LUZ17_RS22440	COG0489	protein tyrosine kinase activity
LUZ17_RS22460	COG1396	sequence-specific DNA binding
LUZ17_RS22465	COG3550	peptidyl-serine autophosphorylation
LUZ17_RS22470	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LUZ17_RS22475	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LUZ17_RS22490	COG0517	IMP dehydrogenase activity
LUZ17_RS22490	COG1125	glycine betaine transport
LUZ17_RS22505	COG1119	ATPase activity
LUZ17_RS22515	COG1752	Esterase of the alpha-beta hydrolase superfamily
LUZ17_RS22530	COG3039	Transposase
LUZ17_RS22555	COG0656	L-ascorbic acid biosynthetic process
LUZ17_RS22560	COG2130	NADP-dependent
LUZ17_RS22565	COG0667	Aldo Keto reductase
LUZ17_RS22575	COG1187	pseudouridine synthase activity
LUZ17_RS22590	COG1643	Atp-dependent helicase
LUZ17_RS22595	COG4807	Protein conserved in bacteria
LUZ17_RS22600	COG4948	Mandelate Racemase Muconate Lactonizing
LUZ17_RS22605	COG0179	Fumarylacetoacetate (FAA) hydrolase
LUZ17_RS22610	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_RS22670	COG3162	membrane
LUZ17_RS22675	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LUZ17_RS22690	COG0708	Exodeoxyribonuclease III
LUZ17_RS22705	COG2091	lysine biosynthetic process via aminoadipic acid
LUZ17_RS22715	COG3540	Alkaline phosphatase
LUZ17_RS22765	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LUZ17_RS22770	COG0583	DNA-binding transcription factor activity
LUZ17_RS22775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LUZ17_RS22790	COG0210	DNA helicase
LUZ17_RS22805	COG0531	amino acid
LUZ17_RS22815	COG1322	Protein conserved in bacteria
LUZ17_RS22825	COG0386	Belongs to the glutathione peroxidase family
LUZ17_RS22875	COG0793	Belongs to the peptidase S41A family
LUZ17_RS22880	COG4942	peptidase
LUZ17_RS22890	COG2234	aminopeptidase activity
LUZ17_RS22935	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LUZ17_RS22940	COG0302	gtp cyclohydrolase
LUZ17_RS22965	COG0477	Major facilitator Superfamily
LUZ17_RS23060	COG1929	Belongs to the glycerate kinase type-1 family
LUZ17_RS23065	COG2271	Major facilitator Superfamily
LUZ17_RS23080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LUZ17_RS23085	COG0861	Integral membrane protein TerC family
LUZ17_RS23095	COG0584	glycerophosphoryl diester phosphodiesterase
LUZ17_RS23105	COG0671	phosphoesterase, PA-phosphatase related
LUZ17_RS23115	COG0726	polysaccharide deacetylase