locus-tag	class	description
BCR61_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BCR61_RS00030	COG0187	DNA topoisomerase II activity
BCR61_RS00040	COG0501	Belongs to the peptidase M48B family
BCR61_RS00070	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BCR61_RS00080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCR61_RS00090	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BCR61_RS00100	COG4772	TonB-dependent receptor
BCR61_RS00115	COG3039	Transposase
BCR61_RS00120	COG1304	FMN binding
BCR61_RS00140	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BCR61_RS00150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCR61_RS00225	COG3039	Transposase
BCR61_RS00240	COG2826	transposase and inactivated derivatives, IS30 family
BCR61_RS00265	COG3039	Transposase
BCR61_RS00275	COG1090	epimerase
BCR61_RS00285	COG0642	Histidine kinase
BCR61_RS00295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCR61_RS00405	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCR61_RS00485	COG1511	domain protein
BCR61_RS00485	COG3264	Mechanosensitive ion channel
BCR61_RS00500	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BCR61_RS00510	COG2354	Protein conserved in bacteria
BCR61_RS00515	COG1649	PFAM Uncharacterised BCR, COG1649
BCR61_RS00535	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BCR61_RS00560	COG0702	epimerase
BCR61_RS00570	COG1858	cytochrome C peroxidase
BCR61_RS00655	COG0513	Belongs to the DEAD box helicase family
BCR61_RS00665	COG3039	Transposase
BCR61_RS00715	COG1136	(ABC) transporter
BCR61_RS00735	COG1136	(ABC) transporter
BCR61_RS00780	COG1272	protein, Hemolysin III
BCR61_RS00785	COG1111	helicase
BCR61_RS00785	COG1205	dead DEAH box helicase
BCR61_RS00850	COG0070	glutamate synthase
BCR61_RS00850	COG0069	glutamate synthase activity
BCR61_RS00850	COG0067	glutamate synthase
BCR61_RS00855	COG0493	'glutamate synthase
BCR61_RS00900	COG1609	Transcriptional regulator
BCR61_RS00935	COG0366	Alpha amylase catalytic
BCR61_RS00940	COG0366	Alpha amylase catalytic
BCR61_RS01000	COG0606	chelatase, subunit chli
BCR61_RS01045	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BCR61_RS01050	COG1166	arginine decarboxylase activity
BCR61_RS01115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BCR61_RS01140	COG1028	Short-chain dehydrogenase reductase Sdr
BCR61_RS01165	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BCR61_RS01185	COG0210	DNA helicase
BCR61_RS01200	COG3132	Protein of unknown function, DUF480
BCR61_RS01205	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BCR61_RS01210	COG0284	orotidine-5'-phosphate decarboxylase activity
BCR61_RS01245	COG2937	Belongs to the GPAT DAPAT family
BCR61_RS01275	COG2755	lipolytic protein G-D-S-L family
BCR61_RS01290	COG3186	Phenylalanine-4-hydroxylase
BCR61_RS01295	COG1522	sequence-specific DNA binding
BCR61_RS01345	COG1064	alcohol dehydrogenase
BCR61_RS01355	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BCR61_RS01365	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BCR61_RS01375	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BCR61_RS01395	COG0676	glucose-6-phosphate 1-epimerase activity
BCR61_RS01460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BCR61_RS01490	COG2853	Lipoprotein
BCR61_RS01505	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BCR61_RS01510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BCR61_RS01515	COG1127	ABC transporter
BCR61_RS01595	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCR61_RS01605	COG3039	Transposase
BCR61_RS01610	COG3265	gluconokinase activity
BCR61_RS01615	COG2211	Major facilitator Superfamily
BCR61_RS01620	COG3459	Glycosyltransferase 36 associated
BCR61_RS01635	COG2205	protein histidine kinase activity
BCR61_RS01650	COG1414	Transcriptional regulator
BCR61_RS01655	COG0738	Major facilitator superfamily
BCR61_RS01660	COG3254	rhamnose metabolic process
BCR61_RS01690	COG0339	signal peptide processing
BCR61_RS01720	COG0564	pseudouridine synthase activity
BCR61_RS01730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BCR61_RS01745	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCR61_RS01830	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BCR61_RS01840	COG0842	Transport permease protein
BCR61_RS01845	COG1131	(ABC) transporter
BCR61_RS01870	COG1476	TRANSCRIPTIONal
BCR61_RS01880	COG4555	ABC transporter
BCR61_RS01915	COG0625	glutathione transferase activity
BCR61_RS01965	COG0583	DNA-binding transcription factor activity
BCR61_RS02000	COG1199	ATP-dependent helicase activity
BCR61_RS02020	COG1566	PFAM secretion protein HlyD family protein
BCR61_RS02050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCR61_RS02090	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BCR61_RS02090	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BCR61_RS02095	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BCR61_RS02110	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BCR61_RS02150	COG3237	CsbD-like
BCR61_RS02155	COG0180	Tryptophanyl-tRNA synthetase
BCR61_RS02160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCR61_RS02210	COG0753	catalase activity
BCR61_RS02225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BCR61_RS02235	COG0628	permease
BCR61_RS02250	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BCR61_RS02255	COG1040	competence protein
BCR61_RS02260	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BCR61_RS02265	COG0156	8-amino-7-oxononanoate synthase activity
BCR61_RS02280	COG1028	Short-chain dehydrogenase reductase Sdr
BCR61_RS02295	COG0463	Glycosyl transferase, family 2
BCR61_RS02305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCR61_RS02310	COG3100	YcgL domain-containing protein
BCR61_RS02330	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BCR61_RS02350	COG2239	Acts as a magnesium transporter
BCR61_RS02360	COG0045	succinate-CoA ligase (ADP-forming) activity
BCR61_RS02360	COG1042	CoA-binding domain protein
BCR61_RS02360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCR61_RS02375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCR61_RS02385	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCR61_RS02420	COG3485	protocatechuate 3,4-dioxygenase
BCR61_RS02440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BCR61_RS02445	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCR61_RS02470	COG4221	oxidoreductase activity
BCR61_RS02495	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCR61_RS02520	COG0463	Glycosyl transferase, family 2
BCR61_RS02535	COG1475	DNA binding
BCR61_RS02540	COG1192	Involved in chromosome partitioning
BCR61_RS02555	COG0708	Exodeoxyribonuclease III
BCR61_RS02560	COG2211	Major facilitator Superfamily
BCR61_RS02575	COG0739	heme binding
BCR61_RS02620	COG0745	RESPONSE REGULATOR receiver
BCR61_RS02660	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BCR61_RS02685	COG2814	Major facilitator Superfamily
BCR61_RS02700	COG1289	transmembrane transporter activity
BCR61_RS02725	COG0151	Belongs to the GarS family
BCR61_RS02730	COG0138	bifunctional purine biosynthesis protein purh
BCR61_RS02740	COG2267	carboxylic ester hydrolase activity
BCR61_RS02750	COG2267	carboxylic ester hydrolase activity
BCR61_RS02755	COG2453	phosphatase
BCR61_RS02755	COG0671	phosphoesterase, PA-phosphatase related
BCR61_RS02770	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BCR61_RS02825	COG0439	Biotin carboxylase
BCR61_RS02835	COG0511	ligase activity, forming carbon-carbon bonds
BCR61_RS02840	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BCR61_RS02860	COG1324	tolerance protein
BCR61_RS02895	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BCR61_RS02925	COG0534	Mate efflux family protein
BCR61_RS02930	COG0616	signal peptide processing
BCR61_RS02940	COG1028	Short-chain dehydrogenase reductase Sdr
BCR61_RS02955	COG0009	L-threonylcarbamoyladenylate synthase
BCR61_RS02960	COG1754	DNA topoisomerase type I activity
BCR61_RS02960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCR61_RS02975	COG2922	Belongs to the Smg family
BCR61_RS02980	COG0758	DNA mediated transformation
BCR61_RS02985	COG1652	LysM domain
BCR61_RS02990	COG0242	peptide deformylase activity
BCR61_RS02995	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BCR61_RS03060	COG1560	Kdo2-lipid A biosynthetic process
BCR61_RS03070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCR61_RS03220	COG3039	Transposase
BCR61_RS03230	COG1271	oxidase subunit
BCR61_RS03295	COG2972	Histidine kinase
BCR61_RS03310	COG0531	amino acid
BCR61_RS03330	COG3590	peptidase
BCR61_RS03345	COG0667	Aldo Keto reductase
BCR61_RS03360	COG3384	dioxygenase
BCR61_RS03370	COG1573	uracil-dna glycosylase
BCR61_RS03380	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BCR61_RS03395	COG0025	NhaP-type Na H and K H
BCR61_RS03400	COG1131	(ABC) transporter
BCR61_RS03405	COG0842	Transport permease protein
BCR61_RS03420	COG1404	Belongs to the peptidase S8 family
BCR61_RS03435	COG0745	RESPONSE REGULATOR receiver
BCR61_RS03485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCR61_RS03510	COG2205	protein histidine kinase activity
BCR61_RS03510	COG2202	Pas domain
BCR61_RS03540	COG2813	Specifically methylates the guanine in position
BCR61_RS03545	COG1187	pseudouridine synthase activity
BCR61_RS03550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCR61_RS03590	COG0697	spore germination
BCR61_RS03600	COG2011	ABC-type metal ion transport system permease component
BCR61_RS03630	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCR61_RS03640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCR61_RS03660	COG0356	it plays a direct role in the translocation of protons across the membrane
BCR61_RS03670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BCR61_RS03680	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BCR61_RS03685	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BCR61_RS03690	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BCR61_RS03695	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BCR61_RS03750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCR61_RS03755	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCR61_RS03805	COG0339	signal peptide processing
BCR61_RS03845	COG1956	GAF domain-containing protein
BCR61_RS03850	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BCR61_RS03860	COG0720	synthase
BCR61_RS03870	COG0513	Belongs to the DEAD box helicase family
BCR61_RS03885	COG0625	glutathione transferase activity
BCR61_RS03915	COG0626	cystathionine gamma-synthase activity
BCR61_RS03965	COG3328	transposase activity
BCR61_RS03990	COG2086	electron transfer activity
BCR61_RS04015	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BCR61_RS04015	COG0662	Cupin 2, conserved barrel domain protein
BCR61_RS04020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCR61_RS04060	COG3218	ABC-type transport auxiliary lipoprotein component
BCR61_RS04060	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BCR61_RS04065	COG1127	ABC transporter
BCR61_RS04070	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BCR61_RS04090	COG0442	prolyl-tRNA aminoacylation
BCR61_RS04100	COG1183	phosphatidylcholine synthase activity
BCR61_RS04135	COG3039	Transposase
BCR61_RS04180	COG3039	Transposase
BCR61_RS04210	COG0525	valine-tRNA ligase activity
BCR61_RS04225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BCR61_RS04235	COG0795	lipopolysaccharide-transporting ATPase activity
BCR61_RS04250	COG4974	Belongs to the 'phage' integrase family
BCR61_RS04255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCR61_RS04260	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCR61_RS04260	COG0047	phosphoribosylformylglycinamidine synthase activity
BCR61_RS04270	COG5295	Hep Hag repeat protein
BCR61_RS04280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCR61_RS04290	COG1459	type II secretion system
BCR61_RS04295	COG2165	general secretion pathway protein
BCR61_RS04300	COG4970	Tfp pilus assembly protein FimT
BCR61_RS04305	COG2165	general secretion pathway protein
BCR61_RS04310	COG4795	General secretion pathway protein
BCR61_RS04315	COG3156	type II secretion system protein K
BCR61_RS04320	COG3166	PFAM Fimbrial assembly family protein
BCR61_RS04335	COG1450	Type ii and iii secretion system protein
BCR61_RS04350	COG2188	Transcriptional regulator
BCR61_RS04405	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BCR61_RS04410	COG1518	maintenance of DNA repeat elements
BCR61_RS04450	COG3039	Transposase
BCR61_RS04475	COG1399	metal-binding, possibly nucleic acid-binding protein
BCR61_RS04500	COG1028	Short-chain dehydrogenase reductase Sdr
BCR61_RS04505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCR61_RS04515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCR61_RS04520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BCR61_RS04545	COG3039	Transposase
BCR61_RS04555	COG3829	transcription factor binding
BCR61_RS04645	COG2826	transposase and inactivated derivatives, IS30 family
BCR61_RS04655	COG0678	peroxiredoxin activity
BCR61_RS04675	COG0330	HflC and HflK could
BCR61_RS04680	COG0330	HflC and HflK could
BCR61_RS04690	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BCR61_RS04695	COG0308	aminopeptidase N
BCR61_RS04760	COG1560	Kdo2-lipid A biosynthetic process
BCR61_RS04765	COG1519	Transferase
BCR61_RS04770	COG1538	Outer membrane efflux protein
BCR61_RS04775	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BCR61_RS04805	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BCR61_RS04810	COG0066	3-isopropylmalate dehydratase activity
BCR61_RS04815	COG2226	methyltransferase
BCR61_RS04845	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BCR61_RS04855	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BCR61_RS04860	COG3710	Transcriptional regulator
BCR61_RS04885	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BCR61_RS04905	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BCR61_RS04940	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BCR61_RS04950	COG3781	membrane
BCR61_RS05100	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BCR61_RS05120	COG1217	gtp-binding protein TYPA
BCR61_RS05125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCR61_RS05130	COG0039	L-malate dehydrogenase activity
BCR61_RS05135	COG0625	glutathione transferase activity
BCR61_RS05155	COG3039	Transposase
BCR61_RS05195	COG0584	glycerophosphoryl diester phosphodiesterase
BCR61_RS05230	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCR61_RS05265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCR61_RS05275	COG0583	DNA-binding transcription factor activity
BCR61_RS05280	COG3634	alkyl hydroperoxide reductase activity
BCR61_RS05290	COG2890	protein-(glutamine-N5) methyltransferase activity
BCR61_RS05330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCR61_RS05330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCR61_RS05345	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BCR61_RS05370	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BCR61_RS05400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCR61_RS05410	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCR61_RS05440	COG1295	ribonuclease BN
BCR61_RS05445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCR61_RS05465	COG0521	Mo-molybdopterin cofactor biosynthetic process
BCR61_RS05475	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BCR61_RS05480	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BCR61_RS05490	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BCR61_RS05505	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BCR61_RS05515	COG0193	aminoacyl-tRNA hydrolase activity
BCR61_RS05520	COG0012	GTP binding
BCR61_RS05550	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCR61_RS05555	COG0250	Participates in transcription elongation, termination and antitermination
BCR61_RS05565	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BCR61_RS05575	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BCR61_RS05580	COG0222	ribosome binding
BCR61_RS05585	COG0085	RNA polymerase activity
BCR61_RS05590	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BCR61_RS05595	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BCR61_RS05600	COG0049	tRNA binding
BCR61_RS05620	COG0051	transcription antitermination factor activity, RNA binding
BCR61_RS05625	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BCR61_RS05630	COG0088	Forms part of the polypeptide exit tunnel
BCR61_RS05635	COG0089	rRNA binding
BCR61_RS05650	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BCR61_RS05660	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BCR61_RS05665	COG0255	Belongs to the universal ribosomal protein uL29 family
BCR61_RS05670	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BCR61_RS05675	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BCR61_RS05685	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BCR61_RS05715	COG1841	ribosomal large subunit assembly
BCR61_RS05725	COG0201	protein transport
BCR61_RS05735	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BCR61_RS05740	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BCR61_RS05750	COG0203	ribosomal protein L17
BCR61_RS05815	COG3551	Protein conserved in bacteria
BCR61_RS05845	COG2194	sulfuric ester hydrolase activity
BCR61_RS05855	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BCR61_RS05860	COG0745	RESPONSE REGULATOR receiver
BCR61_RS05865	COG0642	Histidine kinase
BCR61_RS05875	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BCR61_RS05880	COG2894	cell division
BCR61_RS05900	COG4585	Histidine kinase
BCR61_RS05905	COG2197	response regulator
BCR61_RS05920	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BCR61_RS05945	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BCR61_RS05950	COG2963	transposase activity
BCR61_RS06050	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BCR61_RS06060	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BCR61_RS06070	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BCR61_RS06115	COG3328	transposase activity
BCR61_RS06130	COG3179	chitinase
BCR61_RS06250	COG3039	Transposase
BCR61_RS06300	COG0793	Belongs to the peptidase S41A family
BCR61_RS06305	COG4942	peptidase
BCR61_RS06315	COG2234	aminopeptidase activity
BCR61_RS06345	COG3039	Transposase
BCR61_RS06410	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BCR61_RS06430	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BCR61_RS06435	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BCR61_RS06440	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BCR61_RS06455	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BCR61_RS06540	COG0587	DNA-directed DNA polymerase activity
BCR61_RS06560	COG1297	OPT oligopeptide transporter protein
BCR61_RS06585	COG1506	peptidase
BCR61_RS06585	COG0823	Involved in the tonB-independent uptake of proteins
BCR61_RS06605	COG1917	Cupin 2, conserved barrel domain protein
BCR61_RS06605	COG2207	Transcriptional regulator
BCR61_RS06635	COG0753	catalase activity
BCR61_RS06680	COG0469	pyruvate kinase activity
BCR61_RS06685	COG3588	fructose-bisphosphate aldolase
BCR61_RS06690	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BCR61_RS06735	COG2198	Histidine kinase
BCR61_RS06735	COG2205	protein histidine kinase activity
BCR61_RS06735	COG0784	Response regulator, receiver
BCR61_RS06755	COG0175	sulfate reduction
BCR61_RS06760	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCR61_RS06765	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BCR61_RS06770	COG0175	sulfate reduction
BCR61_RS06775	COG2895	sulfate adenylyltransferase (ATP) activity
BCR61_RS06775	COG0529	Catalyzes the synthesis of activated sulfate
BCR61_RS06785	COG3039	Transposase
BCR61_RS06800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCR61_RS06805	COG0308	aminopeptidase N
BCR61_RS06835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCR61_RS06855	COG1970	mechanosensitive ion channel activity
BCR61_RS06885	COG3273	potassium ion transport
BCR61_RS06885	COG0471	metal ion transport
BCR61_RS06900	COG2022	thiamine diphosphate biosynthetic process
BCR61_RS07040	COG3118	belongs to the thioredoxin family
BCR61_RS07070	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BCR61_RS07095	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BCR61_RS07125	COG2968	Membrane
BCR61_RS07140	COG3164	Protein of unknown function
BCR61_RS07150	COG0312	modulator of DNA gyrase
BCR61_RS07155	COG3028	Belongs to the UPF0307 family
BCR61_RS07160	COG0312	modulator of DNA gyrase
BCR61_RS07195	COG0142	geranyltranstransferase activity
BCR61_RS07200	COG1722	exodeoxyribonuclease VII activity
BCR61_RS07205	COG0037	tRNA processing
BCR61_RS07210	COG1785	Belongs to the alkaline phosphatase family
BCR61_RS07215	COG1301	dicarboxylic acid transport
BCR61_RS07230	COG0791	NLP P60 protein
BCR61_RS07235	COG0791	NLP P60 protein
BCR61_RS07240	COG1047	Peptidyl-prolyl cis-trans
BCR61_RS07245	COG2311	Membrane
BCR61_RS07250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCR61_RS07295	COG0489	protein tyrosine kinase activity
BCR61_RS07300	COG0717	Belongs to the dCTP deaminase family
BCR61_RS07320	COG0412	Dienelactone hydrolase
BCR61_RS07330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCR61_RS07385	COG2890	protein-(glutamine-N5) methyltransferase activity
BCR61_RS07390	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BCR61_RS07395	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCR61_RS07400	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCR61_RS07420	COG0101	tRNA pseudouridine synthase activity
BCR61_RS07425	COG0135	phosphoribosylanthranilate isomerase activity
BCR61_RS07445	COG0159	tryptophan synthase activity
BCR61_RS07455	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BCR61_RS07460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCR61_RS07510	COG0149	triose-phosphate isomerase activity
BCR61_RS07525	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCR61_RS07535	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCR61_RS07540	COG0649	NAD binding
BCR61_RS07545	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BCR61_RS07550	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BCR61_RS07555	COG1034	ATP synthesis coupled electron transport
BCR61_RS07560	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BCR61_RS07590	COG1007	ATP synthesis coupled electron transport
BCR61_RS07600	COG0779	Required for maturation of 30S ribosomal subunits
BCR61_RS07605	COG0195	Participates in both transcription termination and antitermination
BCR61_RS07610	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BCR61_RS07625	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BCR61_RS07630	COG1185	polyribonucleotide nucleotidyltransferase activity
BCR61_RS07665	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BCR61_RS07675	COG2095	MarC family integral membrane protein
BCR61_RS07690	COG1611	Belongs to the LOG family
BCR61_RS07730	COG4969	Belongs to the N-Me-Phe pilin family
BCR61_RS07735	COG0556	nucleotide-excision repair
BCR61_RS07770	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BCR61_RS07785	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BCR61_RS07840	COG0438	transferase activity, transferring glycosyl groups
BCR61_RS07845	COG0438	transferase activity, transferring glycosyl groups
BCR61_RS07855	COG0438	transferase activity, transferring glycosyl groups
BCR61_RS07895	COG3040	lipid binding
BCR61_RS07980	COG0784	Response regulator, receiver
BCR61_RS07980	COG4191	Histidine kinase
BCR61_RS08005	COG0552	protein localization to endoplasmic reticulum
BCR61_RS08015	COG3938	Belongs to the proline racemase family
BCR61_RS08020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCR61_RS08035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCR61_RS08045	COG0006	proline dipeptidase activity
BCR61_RS08060	COG0531	amino acid
BCR61_RS08110	COG4206	TonB-dependent receptor
BCR61_RS08140	COG3328	transposase activity
BCR61_RS08210	COG0746	molybdenum cofactor guanylyltransferase activity
BCR61_RS08235	COG1648	precorrin-2 dehydrogenase activity
BCR61_RS08235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BCR61_RS08265	COG3039	Transposase
BCR61_RS08270	COG3039	Transposase
BCR61_RS08300	COG3039	Transposase
BCR61_RS08315	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BCR61_RS08335	COG1054	Belongs to the UPF0176 family
BCR61_RS08355	COG1530	ribonuclease E activity
BCR61_RS08365	COG3064	Membrane
BCR61_RS08370	COG0428	transporter
BCR61_RS08375	COG0428	transporter
BCR61_RS08385	COG2154	pterin-4-alpha-carbinolamine dehydratase
BCR61_RS08390	COG0316	Belongs to the HesB IscA family
BCR61_RS08390	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BCR61_RS08440	COG3039	Transposase
BCR61_RS08570	COG0631	protein serine/threonine phosphatase activity
BCR61_RS08605	COG1858	cytochrome C peroxidase
BCR61_RS08670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCR61_RS08675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCR61_RS08695	COG2201	protein-glutamate methylesterase activity
BCR61_RS08740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCR61_RS08760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCR61_RS08775	COG1595	DNA-templated transcription, initiation
BCR61_RS08825	COG2244	polysaccharide biosynthetic process
BCR61_RS08855	COG2264	protein methyltransferase activity
BCR61_RS08865	COG0438	transferase activity, transferring glycosyl groups
BCR61_RS08880	COG1136	(ABC) transporter
BCR61_RS08885	COG1132	(ABC) transporter
BCR61_RS08895	COG0477	Major facilitator Superfamily
BCR61_RS08915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCR61_RS08930	COG1253	flavin adenine dinucleotide binding
BCR61_RS08945	COG0306	phosphate transporter
BCR61_RS08975	COG0504	CTP synthase activity
BCR61_RS08980	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BCR61_RS08990	COG0148	phosphopyruvate hydratase activity
BCR61_RS08995	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BCR61_RS09000	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BCR61_RS09010	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BCR61_RS09025	COG2840	Smr protein MutS2
BCR61_RS09030	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BCR61_RS09035	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BCR61_RS09040	COG1238	metal cluster binding
BCR61_RS09055	COG1534	Rna-binding protein
BCR61_RS09060	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BCR61_RS09070	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BCR61_RS09075	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BCR61_RS09085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCR61_RS09090	COG1546	Belongs to the CinA family
BCR61_RS09105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BCR61_RS09115	COG2137	regulation of response to DNA damage stimulus
BCR61_RS09120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCR61_RS09125	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BCR61_RS09150	COG0305	Participates in initiation and elongation during chromosome replication
BCR61_RS09155	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BCR61_RS09180	COG1741	Belongs to the pirin family
BCR61_RS09185	COG0583	DNA-binding transcription factor activity
BCR61_RS09215	COG0351	phosphomethylpyrimidine kinase
BCR61_RS09225	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BCR61_RS09230	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BCR61_RS09250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCR61_RS09260	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BCR61_RS09265	COG3734	2-keto-3-deoxy-galactonokinase
BCR61_RS09275	COG4948	Mandelate Racemase Muconate Lactonizing
BCR61_RS09280	COG0800	Aldolase
BCR61_RS09295	COG1501	Belongs to the glycosyl hydrolase 31 family
BCR61_RS09305	COG1070	Carbohydrate kinase
BCR61_RS09315	COG0477	Major facilitator Superfamily
BCR61_RS09335	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BCR61_RS09385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCR61_RS09390	COG2258	MOSC domain
BCR61_RS09400	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BCR61_RS09405	COG0505	Belongs to the CarA family
BCR61_RS09415	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BCR61_RS09420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCR61_RS09430	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCR61_RS09505	COG0784	Response regulator, receiver
BCR61_RS09505	COG2198	Histidine kinase
BCR61_RS09505	COG2205	protein histidine kinase activity
BCR61_RS09510	COG1024	Enoyl-CoA hydratase
BCR61_RS09515	COG0318	PFAM AMP-dependent synthetase and ligase
BCR61_RS09545	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BCR61_RS09580	COG0840	transmembrane signaling receptor activity
BCR61_RS09600	COG3039	Transposase
BCR61_RS09620	COG0835	chemotaxis
BCR61_RS09640	COG0840	transmembrane signaling receptor activity
BCR61_RS09645	COG0840	transmembrane signaling receptor activity
BCR61_RS09650	COG0840	transmembrane signaling receptor activity
BCR61_RS09655	COG0840	transmembrane signaling receptor activity
BCR61_RS09665	COG0840	transmembrane signaling receptor activity
BCR61_RS09675	COG0840	transmembrane signaling receptor activity
BCR61_RS09710	COG0745	RESPONSE REGULATOR receiver
BCR61_RS09720	COG0835	chemotaxis
BCR61_RS09730	COG1360	Flagellar Motor Protein
BCR61_RS09735	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BCR61_RS09755	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCR61_RS09765	COG4771	TonB-dependent receptor
BCR61_RS09815	COG3039	Transposase
BCR61_RS09965	COG3039	Transposase
BCR61_RS10000	COG3039	Transposase
BCR61_RS10015	COG3039	Transposase
BCR61_RS10030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCR61_RS10030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCR61_RS10035	COG1105	Belongs to the carbohydrate kinase PfkB family
BCR61_RS10040	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCR61_RS10040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCR61_RS10045	COG1609	Transcriptional regulator
BCR61_RS10070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCR61_RS10075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCR61_RS10085	COG2902	Dehydrogenase
BCR61_RS10095	COG3039	Transposase
BCR61_RS10105	COG0784	Response regulator, receiver
BCR61_RS10105	COG2205	protein histidine kinase activity
BCR61_RS10105	COG5002	protein histidine kinase activity
BCR61_RS10110	COG2733	membrane
BCR61_RS10120	COG1121	(ABC) transporter
BCR61_RS10125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCR61_RS10135	COG2223	nitrite transmembrane transporter activity
BCR61_RS10145	COG0243	molybdopterin cofactor binding
BCR61_RS10155	COG0477	Major facilitator Superfamily
BCR61_RS10165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCR61_RS10170	COG0174	glutamine synthetase
BCR61_RS10215	COG3842	ATPase activity
BCR61_RS10245	COG1012	belongs to the aldehyde dehydrogenase family
BCR61_RS10260	COG4535	Mg2 and Co2 transporter CorC
BCR61_RS10280	COG1702	phosphate starvation-inducible protein PhoH
BCR61_RS10305	COG0741	lytic transglycosylase activity
BCR61_RS10315	COG0723	plastoquinol--plastocyanin reductase activity
BCR61_RS10320	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BCR61_RS10325	COG2857	Cytochrome c1
BCR61_RS10330	COG0625	glutathione transferase activity
BCR61_RS10335	COG2969	positive regulation of protein catabolic process
BCR61_RS10380	COG3328	transposase activity
BCR61_RS10465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BCR61_RS10485	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BCR61_RS10490	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BCR61_RS10490	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BCR61_RS10495	COG0802	atpase or kinase
BCR61_RS10500	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCR61_RS10505	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BCR61_RS10530	COG1028	Short-chain dehydrogenase reductase Sdr
BCR61_RS10540	COG0501	Belongs to the peptidase M48B family
BCR61_RS10550	COG2081	HI0933 family
BCR61_RS10555	COG4681	YaeQ
BCR61_RS10560	COG1671	Belongs to the UPF0178 family
BCR61_RS10570	COG0625	glutathione transferase activity
BCR61_RS10580	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BCR61_RS10585	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BCR61_RS10590	COG0513	Belongs to the DEAD box helicase family
BCR61_RS10595	COG0488	(ABC) transporter
BCR61_RS10620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCR61_RS10625	COG0483	inositol monophosphate 1-phosphatase activity
BCR61_RS10640	COG3300	MHYT domain
BCR61_RS10640	COG5001	Diguanylate cyclase
BCR61_RS10645	COG1509	lysine 2,3-aminomutase activity
BCR61_RS10660	COG0402	S-adenosylhomocysteine deaminase activity
BCR61_RS10665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BCR61_RS10695	COG4677	pectinesterase activity
BCR61_RS10720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BCR61_RS10745	COG2166	iron-sulfur cluster assembly
BCR61_RS10765	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BCR61_RS10770	COG0137	argininosuccinate synthase activity
BCR61_RS10780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCR61_RS10785	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BCR61_RS10800	COG0165	Argininosuccinate lyase
BCR61_RS10820	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BCR61_RS10855	COG3039	Transposase
BCR61_RS10870	COG4988	ABC transporter
BCR61_RS10875	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BCR61_RS10885	COG3039	Transposase
BCR61_RS10995	COG3039	Transposase
BCR61_RS11010	COG3209	COG3209 Rhs family protein
BCR61_RS11020	COG3039	Transposase
BCR61_RS11060	COG0643	Histidine kinase
BCR61_RS11060	COG2198	Histidine kinase
BCR61_RS11060	COG0784	Response regulator, receiver
BCR61_RS11115	COG1684	flagellar biosynthetic protein fliR
BCR61_RS11135	COG3190	flagellar
BCR61_RS11185	COG1677	Flagellar hook-basal body complex protein FliE
BCR61_RS11220	COG1028	Short-chain dehydrogenase reductase Sdr
BCR61_RS11230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCR61_RS11250	COG2201	protein-glutamate methylesterase activity
BCR61_RS11280	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BCR61_RS11285	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BCR61_RS11325	COG4787	bacterial-type flagellum-dependent cell motility
BCR61_RS11335	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BCR61_RS11340	COG1558	bacterial-type flagellum-dependent cell motility
BCR61_RS11350	COG0835	chemotaxis
BCR61_RS11350	COG0784	Response regulator, receiver
BCR61_RS11370	COG5002	protein histidine kinase activity
BCR61_RS11380	COG4585	Histidine kinase
BCR61_RS11385	COG5001	Diguanylate cyclase
BCR61_RS11410	COG0482	sulfurtransferase activity
BCR61_RS11425	COG0542	response to heat
BCR61_RS11450	COG0492	ferredoxin-NADP+ reductase activity
BCR61_RS11455	COG1674	ftsk spoiiie
BCR61_RS11480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BCR61_RS11500	COG0038	chloride channel
BCR61_RS11505	COG0183	Belongs to the thiolase family
BCR61_RS11510	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCR61_RS11510	COG1024	Enoyl-CoA hydratase
BCR61_RS11525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BCR61_RS11535	COG1426	Protein conserved in bacteria
BCR61_RS11545	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCR61_RS11555	COG0303	'Molybdopterin
BCR61_RS11610	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCR61_RS11670	COG0742	ribosomal rna small subunit methyltransferase
BCR61_RS11675	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BCR61_RS11690	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCR61_RS11695	COG0405	Gamma-glutamyltransferase
BCR61_RS11805	COG0343	queuine tRNA-ribosyltransferase activity
BCR61_RS11810	COG1862	Preprotein translocase
BCR61_RS11815	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCR61_RS11820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCR61_RS11860	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCR61_RS11870	COG0704	Plays a role in the regulation of phosphate uptake
BCR61_RS11885	COG0573	inorganic phosphate transmembrane transporter activity
BCR61_RS11890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCR61_RS11935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BCR61_RS11945	COG1024	Enoyl-CoA hydratase
BCR61_RS11955	COG0494	nUDIX hydrolase
BCR61_RS12000	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BCR61_RS12000	COG0116	Belongs to the methyltransferase superfamily
BCR61_RS12025	COG0667	Aldo Keto reductase
BCR61_RS12035	COG2925	Exonuclease
BCR61_RS12065	COG0288	reversible hydration of carbon dioxide
BCR61_RS12100	COG0316	Belongs to the HesB IscA family
BCR61_RS12105	COG0360	Binds together with S18 to 16S ribosomal RNA
BCR61_RS12115	COG0359	binds to the 23S rRNA
BCR61_RS12125	COG3115	cell septum assembly
BCR61_RS12140	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BCR61_RS12160	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BCR61_RS12185	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BCR61_RS12195	COG2986	histidine ammonia-lyase
BCR61_RS12200	COG1228	amidohydrolase
BCR61_RS12245	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BCR61_RS12255	COG0077	Prephenate dehydratase
BCR61_RS12255	COG1605	Chorismate mutase
BCR61_RS12260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BCR61_RS12290	COG4566	intracellular signal transduction
BCR61_RS12340	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCR61_RS12345	COG1469	GTP cyclohydrolase I activity
BCR61_RS12355	COG0617	tRNA 3'-terminal CCA addition
BCR61_RS12365	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BCR61_RS12370	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BCR61_RS12405	COG1472	Belongs to the glycosyl hydrolase 3 family
BCR61_RS12425	COG5001	Diguanylate cyclase
BCR61_RS12425	COG2203	Gaf domain
BCR61_RS12425	COG3706	GGDEF domain
BCR61_RS12425	COG4251	negative regulation of phosphorylation
BCR61_RS12485	COG1595	DNA-templated transcription, initiation
BCR61_RS12515	COG0386	Belongs to the glutathione peroxidase family
BCR61_RS12595	COG3039	Transposase
BCR61_RS12610	COG2205	protein histidine kinase activity
BCR61_RS12610	COG0784	Response regulator, receiver
BCR61_RS12610	COG5002	protein histidine kinase activity
BCR61_RS12645	COG0800	Aldolase
BCR61_RS12650	COG0129	dihydroxy-acid dehydratase activity
BCR61_RS12655	COG0363	glucosamine-6-phosphate deaminase activity
BCR61_RS12665	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BCR61_RS12680	COG0354	folic acid binding
BCR61_RS12695	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BCR61_RS12710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BCR61_RS12725	COG4591	ABC-type transport system involved in lipoprotein release permease component
BCR61_RS12755	COG0811	peptide transport
BCR61_RS12770	COG1663	tetraacyldisaccharide 4'-kinase activity
BCR61_RS12780	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BCR61_RS12790	COG0322	excinuclease ABC activity
BCR61_RS12825	COG3328	transposase activity
BCR61_RS12850	COG3039	Transposase
BCR61_RS12860	COG2801	Transposase and inactivated derivatives
BCR61_RS12870	COG2201	protein-glutamate methylesterase activity
BCR61_RS12915	COG0653	protein targeting
BCR61_RS13150	COG0140	phosphoribosyl-ATP diphosphatase activity
BCR61_RS13150	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BCR61_RS13160	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BCR61_RS13170	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BCR61_RS13170	COG0131	Imidazoleglycerol-phosphate dehydratase
BCR61_RS13185	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BCR61_RS13205	COG0124	histidyl-tRNA synthetase
BCR61_RS13220	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BCR61_RS13255	COG1012	belongs to the aldehyde dehydrogenase family
BCR61_RS13270	COG0167	dihydroorotate dehydrogenase activity
BCR61_RS13275	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BCR61_RS13280	COG0697	spore germination
BCR61_RS13290	COG1794	racemase activity, acting on amino acids and derivatives
BCR61_RS13315	COG0671	phosphoesterase, PA-phosphatase related
BCR61_RS13330	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BCR61_RS13345	COG2183	response to ionizing radiation
BCR61_RS13355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCR61_RS13355	COG0723	plastoquinol--plastocyanin reductase activity
BCR61_RS13370	COG3243	poly(R)-hydroxyalkanoic acid synthase
BCR61_RS13380	COG1183	phosphatidylcholine synthase activity
BCR61_RS13385	COG1028	Short-chain dehydrogenase reductase Sdr
BCR61_RS13410	COG0668	transmembrane transport
BCR61_RS13430	COG1914	H( )-stimulated, divalent metal cation uptake system
BCR61_RS13490	COG0583	DNA-binding transcription factor activity
BCR61_RS13495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCR61_RS13500	COG3002	Belongs to the UPF0753 family
BCR61_RS13515	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BCR61_RS13535	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCR61_RS13545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCR61_RS13550	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BCR61_RS13560	COG0776	regulation of translation
BCR61_RS13565	COG0539	negative regulation of cytoplasmic translation
BCR61_RS13570	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BCR61_RS13585	COG2957	Belongs to the agmatine deiminase family
BCR61_RS13595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCR61_RS13620	COG0395	ABC-type sugar transport system, permease component
BCR61_RS13625	COG1175	transmembrane transport
BCR61_RS13655	COG2350	Protein conserved in bacteria
BCR61_RS13660	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BCR61_RS13665	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BCR61_RS13670	COG1187	pseudouridine synthase activity
BCR61_RS13695	COG0436	Aminotransferase
BCR61_RS13760	COG0277	FAD linked oxidase domain protein
BCR61_RS13765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCR61_RS13775	COG0531	amino acid
BCR61_RS13780	COG0531	amino acid
BCR61_RS13785	COG0235	Class ii aldolase
BCR61_RS13790	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BCR61_RS13825	COG2201	protein-glutamate methylesterase activity
BCR61_RS13885	COG0583	DNA-binding transcription factor activity
BCR61_RS13895	COG3039	Transposase
BCR61_RS14010	COG3039	Transposase
BCR61_RS14025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCR61_RS14045	COG0557	exoribonuclease II activity
BCR61_RS14075	COG1960	acyl-CoA dehydrogenase activity
BCR61_RS14080	COG2226	methyltransferase
BCR61_RS14085	COG1410	methionine synthase
BCR61_RS14085	COG0646	methionine synthase
BCR61_RS14090	COG1410	methionine synthase
BCR61_RS14090	COG0646	methionine synthase
BCR61_RS14100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCR61_RS14110	COG1609	Transcriptional regulator
BCR61_RS14125	COG2900	Belongs to the SlyX family
BCR61_RS14140	COG0386	Belongs to the glutathione peroxidase family
BCR61_RS14150	COG1725	Transcriptional regulator
BCR61_RS14155	COG1131	(ABC) transporter
BCR61_RS14220	COG2850	peptidyl-arginine hydroxylation
BCR61_RS14255	COG1132	(ABC) transporter
BCR61_RS14270	COG0583	DNA-binding transcription factor activity
BCR61_RS14290	COG1605	Chorismate mutase
BCR61_RS14290	COG0287	Prephenate dehydrogenase
BCR61_RS14295	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BCR61_RS14305	COG0484	heat shock protein binding
BCR61_RS14310	COG0443	Heat shock 70 kDa protein
BCR61_RS14315	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BCR61_RS14325	COG0497	DNA recombination
BCR61_RS14335	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCR61_RS14345	COG2914	Belongs to the UPF0125 (RnfH) family
BCR61_RS14355	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BCR61_RS14370	COG1960	acyl-CoA dehydrogenase activity
BCR61_RS14380	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BCR61_RS14435	COG2814	Major facilitator Superfamily
BCR61_RS14440	COG1566	PFAM secretion protein HlyD family protein
BCR61_RS14455	COG2207	Transcriptional regulator
BCR61_RS14485	COG4774	siderophore transport
BCR61_RS14500	COG0367	asparagine synthase
BCR61_RS14515	COG1393	Belongs to the ArsC family
BCR61_RS14530	COG3039	Transposase
BCR61_RS14580	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BCR61_RS14595	COG0233	cytoplasmic translational termination
BCR61_RS14605	COG0575	Belongs to the CDS family
BCR61_RS14615	COG0750	zinc metalloprotease
BCR61_RS14635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCR61_RS14640	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCR61_RS14660	COG0825	malonyl-CoA metabolic process
BCR61_RS14670	COG4771	TonB-dependent receptor
BCR61_RS14675	COG1131	(ABC) transporter
BCR61_RS14695	COG1981	membrane
BCR61_RS14740	COG0529	Catalyzes the synthesis of activated sulfate
BCR61_RS14740	COG2895	sulfate adenylyltransferase (ATP) activity
BCR61_RS14775	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BCR61_RS14790	COG2040	homocysteine
BCR61_RS14795	COG0833	amino acid
BCR61_RS14815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCR61_RS14815	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCR61_RS14830	COG2878	Part of a membrane complex involved in electron transport
BCR61_RS14850	COG1595	DNA-templated transcription, initiation
BCR61_RS14875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BCR61_RS14890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BCR61_RS14895	COG0251	oxidation-reduction process
BCR61_RS14905	COG0392	lysyltransferase activity
BCR61_RS14905	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BCR61_RS14935	COG3039	Transposase
BCR61_RS14960	COG2814	Major facilitator Superfamily
BCR61_RS14965	COG1902	pentaerythritol trinitrate reductase activity
BCR61_RS14980	COG2824	Alkylphosphonate utilization operon protein PhnA
BCR61_RS14995	COG1047	Peptidyl-prolyl cis-trans
BCR61_RS15045	COG3039	Transposase
BCR61_RS15050	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BCR61_RS15065	COG1451	nucleotide metabolic process
BCR61_RS15090	COG0183	Belongs to the thiolase family
BCR61_RS15120	COG1793	dna ligase
BCR61_RS15120	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BCR61_RS15130	COG1793	dna ligase
BCR61_RS15135	COG1201	RNA secondary structure unwinding
BCR61_RS15155	COG1278	Cold shock
BCR61_RS15160	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BCR61_RS15165	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BCR61_RS15175	COG3046	protein related to deoxyribodipyrimidine photolyase
BCR61_RS15185	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BCR61_RS15220	COG3039	Transposase
BCR61_RS15230	COG2954	triphosphatase activity
BCR61_RS15245	COG1381	Involved in DNA repair and RecF pathway recombination
BCR61_RS15275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCR61_RS15290	COG1024	Enoyl-CoA hydratase
BCR61_RS15290	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCR61_RS15310	COG1024	Enoyl-CoA hydratase
BCR61_RS15315	COG1960	acyl-CoA dehydrogenase activity
BCR61_RS15385	COG2353	YceI-like domain
BCR61_RS15395	COG2353	YceI-like domain
BCR61_RS15410	COG1760	l-serine dehydratase
BCR61_RS15420	COG0626	cystathionine gamma-synthase activity
BCR61_RS15425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BCR61_RS15430	COG0739	heme binding
BCR61_RS15440	COG1272	protein, Hemolysin III
BCR61_RS15460	COG0463	Glycosyl transferase, family 2
BCR61_RS15470	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BCR61_RS15480	COG4771	TonB-dependent receptor
BCR61_RS15485	COG1309	transcriptional regulator
BCR61_RS15495	COG1960	acyl-CoA dehydrogenase activity
BCR61_RS15530	COG0509	glycine decarboxylation via glycine cleavage system
BCR61_RS15545	COG0330	HflC and HflK could
BCR61_RS15560	COG3956	TIGRFAM MazG family protein
BCR61_RS15570	COG0494	nUDIX hydrolase
BCR61_RS15580	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BCR61_RS15585	COG0837	glucose binding
BCR61_RS15600	COG1388	LysM domain
BCR61_RS15600	COG3858	chitin binding
BCR61_RS15620	COG1472	Belongs to the glycosyl hydrolase 3 family
BCR61_RS15655	COG3537	Alpha-1,2-mannosidase
BCR61_RS15705	COG3142	Participates in the control of copper homeostasis
BCR61_RS15710	COG1446	asparaginase
BCR61_RS15745	COG3039	Transposase
BCR61_RS15770	COG2198	Histidine kinase
BCR61_RS15770	COG0643	Histidine kinase
BCR61_RS15770	COG0784	Response regulator, receiver
BCR61_RS15775	COG0840	transmembrane signaling receptor activity
BCR61_RS15780	COG0835	chemotaxis
BCR61_RS15795	COG0189	ligase activity
BCR61_RS15805	COG1397	ADP-ribosylglycohydrolase
BCR61_RS15815	COG1199	ATP-dependent helicase activity
BCR61_RS15825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCR61_RS15830	COG1215	transferase activity, transferring glycosyl groups
BCR61_RS15840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCR61_RS15860	COG0535	radical SAM domain protein
BCR61_RS15865	COG0535	radical SAM domain protein
BCR61_RS15890	COG1643	Atp-dependent helicase
BCR61_RS15895	COG0783	Belongs to the Dps family
BCR61_RS15905	COG0514	ATP-dependent DNA helicase (RecQ)
BCR61_RS15930	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BCR61_RS15990	COG1187	pseudouridine synthase activity
BCR61_RS16000	COG0602	queuosine metabolic process
BCR61_RS16010	COG2885	chlorophyll binding
BCR61_RS16025	COG0848	biopolymer transport protein
BCR61_RS16035	COG0824	Thioesterase
BCR61_RS16040	COG2255	four-way junction helicase activity
BCR61_RS16050	COG0632	four-way junction helicase activity
BCR61_RS16195	COG3209	COG3209 Rhs family protein
BCR61_RS16220	COG3209	COG3209 Rhs family protein
BCR61_RS16220	COG3209	COG3209 Rhs family protein
BCR61_RS16240	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BCR61_RS16245	COG1845	cytochrome c oxidase, subunit III
BCR61_RS16250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BCR61_RS16265	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BCR61_RS16270	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BCR61_RS16280	COG0196	riboflavin kinase activity
BCR61_RS16285	COG0728	peptidoglycan biosynthetic process
BCR61_RS16290	COG0268	Binds directly to 16S ribosomal RNA
BCR61_RS16295	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BCR61_RS16300	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BCR61_RS16310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BCR61_RS16315	COG0824	Thioesterase
BCR61_RS16330	COG1946	Acyl-CoA thioesterase
BCR61_RS16340	COG1595	DNA-templated transcription, initiation
BCR61_RS16355	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BCR61_RS16395	COG1877	trehalose-phosphatase activity
BCR61_RS16400	COG3387	PFAM Glycoside hydrolase 15-related
BCR61_RS16425	COG0564	pseudouridine synthase activity
BCR61_RS16430	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCR61_RS16435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCR61_RS16435	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BCR61_RS16445	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCR61_RS16450	COG0045	succinate-CoA ligase (ADP-forming) activity
BCR61_RS16490	COG2194	sulfuric ester hydrolase activity
BCR61_RS16495	COG4969	Belongs to the N-Me-Phe pilin family
BCR61_RS16505	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BCR61_RS16530	COG3039	Transposase
BCR61_RS16575	COG1132	(ABC) transporter
BCR61_RS16605	COG0745	RESPONSE REGULATOR receiver
BCR61_RS16610	COG5002	protein histidine kinase activity
BCR61_RS16610	COG5000	phosphorelay sensor kinase activity
BCR61_RS16615	COG0475	glutathione-regulated potassium exporter activity
BCR61_RS16625	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BCR61_RS16650	COG1187	pseudouridine synthase activity
BCR61_RS16655	COG5001	Diguanylate cyclase
BCR61_RS16655	COG5002	protein histidine kinase activity
BCR61_RS16755	COG1028	Short-chain dehydrogenase reductase Sdr
BCR61_RS16775	COG0415	Belongs to the DNA photolyase family
BCR61_RS16780	COG0305	Participates in initiation and elongation during chromosome replication
BCR61_RS16790	COG0367	asparagine synthase
BCR61_RS16805	COG1960	acyl-CoA dehydrogenase activity
BCR61_RS16820	COG0084	hydrolase, TatD family'
BCR61_RS16825	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BCR61_RS16885	COG0735	belongs to the Fur family
BCR61_RS16890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCR61_RS16910	COG3039	Transposase
BCR61_RS16925	COG3039	Transposase
BCR61_RS16930	COG3039	Transposase
BCR61_RS16980	COG2205	protein histidine kinase activity
BCR61_RS17000	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BCR61_RS17010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BCR61_RS17020	COG2198	Histidine kinase
BCR61_RS17020	COG0643	Histidine kinase
BCR61_RS17030	COG0840	transmembrane signaling receptor activity
BCR61_RS17035	COG0835	chemotaxis
BCR61_RS17040	COG2200	EAL domain
BCR61_RS17040	COG2199	diguanylate cyclase activity
BCR61_RS17040	COG2202	Pas domain
BCR61_RS17045	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BCR61_RS17060	COG3590	peptidase
BCR61_RS17080	COG0588	phosphoglycerate mutase activity
BCR61_RS17085	COG1515	deoxyribonuclease V activity
BCR61_RS17095	COG1741	Belongs to the pirin family
BCR61_RS17165	COG1741	Belongs to the pirin family
BCR61_RS17170	COG1966	Carbon starvation protein
BCR61_RS17175	COG2879	small protein
BCR61_RS17220	COG2203	Gaf domain
BCR61_RS17220	COG4251	negative regulation of phosphorylation
BCR61_RS17220	COG3706	GGDEF domain
BCR61_RS17220	COG5001	Diguanylate cyclase
BCR61_RS17230	COG0629	single-stranded DNA binding
BCR61_RS17235	COG0142	geranyltranstransferase activity
BCR61_RS17265	COG0527	aspartate kinase activity
BCR61_RS17275	COG0384	phenazine biosynthesis protein PhzF
BCR61_RS17285	COG1764	response to oxidative stress
BCR61_RS17300	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BCR61_RS17305	COG1678	Uncharacterized ACR, COG1678
BCR61_RS17315	COG0519	Catalyzes the synthesis of GMP from XMP
BCR61_RS17350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BCR61_RS17395	COG0693	protein deglycase activity
BCR61_RS17415	COG1959	2 iron, 2 sulfur cluster binding
BCR61_RS17420	COG0719	Fe-S assembly protein
BCR61_RS17425	COG0396	ATPase activity
BCR61_RS17430	COG0719	Fe-S assembly protein
BCR61_RS17435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCR61_RS17450	COG2146	nitrite reductase [NAD(P)H] activity
BCR61_RS17470	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BCR61_RS17485	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BCR61_RS17495	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BCR61_RS17500	COG0174	glutamine synthetase
BCR61_RS17505	COG3328	transposase activity
BCR61_RS17535	COG0326	Molecular chaperone. Has ATPase activity
BCR61_RS17540	COG2207	Transcriptional regulator
BCR61_RS17565	COG2755	lipolytic protein G-D-S-L family
BCR61_RS17565	COG0657	acetylesterase activity
BCR61_RS17590	COG0488	(ABC) transporter
BCR61_RS17630	COG4651	solute:proton antiporter activity
BCR61_RS17630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCR61_RS17645	COG4772	TonB-dependent receptor
BCR61_RS17655	COG4264	IucA IucC family
BCR61_RS17660	COG2814	Major facilitator Superfamily
BCR61_RS17670	COG0019	diaminopimelate decarboxylase activity
BCR61_RS17730	COG4206	TonB-dependent receptor
BCR61_RS17770	COG0542	response to heat
BCR61_RS17825	COG0534	Mate efflux family protein
BCR61_RS17840	COG0336	Belongs to the RNA methyltransferase TrmD family
BCR61_RS17845	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BCR61_RS17850	COG0228	four-way junction DNA binding
BCR61_RS17875	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BCR61_RS17890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCR61_RS17940	COG1555	photosystem II stabilization
BCR61_RS17945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCR61_RS17960	COG3178	'Phosphotransferase
BCR61_RS17965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BCR61_RS17975	COG0628	permease
BCR61_RS17985	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BCR61_RS18000	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BCR61_RS18025	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BCR61_RS18035	COG0271	Belongs to the BolA IbaG family
BCR61_RS18045	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BCR61_RS18055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BCR61_RS18060	COG1137	ATPase activity
BCR61_RS18075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCR61_RS18080	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BCR61_RS18085	COG1660	Displays ATPase and GTPase activities
BCR61_RS18095	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCR61_RS18100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCR61_RS18110	COG2239	Acts as a magnesium transporter
BCR61_RS18120	COG1294	oxidase, subunit
BCR61_RS18125	COG1271	oxidase subunit
BCR61_RS18145	COG1113	amino acid transport
BCR61_RS18160	COG2197	response regulator
BCR61_RS18165	COG0531	amino acid
BCR61_RS18235	COG0754	glutathionylspermidine amidase activity
BCR61_RS18260	COG1842	Phage shock protein A
BCR61_RS18275	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BCR61_RS18280	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BCR61_RS18290	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BCR61_RS18325	COG2201	protein-glutamate methylesterase activity
BCR61_RS18370	COG2801	Transposase and inactivated derivatives
BCR61_RS18390	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCR61_RS18435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCR61_RS18440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCR61_RS18465	COG3039	Transposase
BCR61_RS18480	COG0745	RESPONSE REGULATOR receiver
BCR61_RS18485	COG2205	protein histidine kinase activity
BCR61_RS18505	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCR61_RS18540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCR61_RS18540	COG3453	Protein conserved in bacteria
BCR61_RS18545	COG0725	ABC transporter, periplasmic molybdate-binding protein
BCR61_RS18550	COG4149	molybdate abc transporter
BCR61_RS18555	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BCR61_RS18575	COG0642	Histidine kinase
BCR61_RS18590	COG1028	Short-chain dehydrogenase reductase Sdr
BCR61_RS18600	COG1022	Amp-dependent synthetase and ligase
BCR61_RS18625	COG1376	ErfK ybiS ycfS ynhG family protein
BCR61_RS18630	COG0739	heme binding
BCR61_RS18640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BCR61_RS18645	COG1301	dicarboxylic acid transport
BCR61_RS18665	COG2304	oxidoreductase activity
BCR61_RS18685	COG0714	Associated with various cellular activities
BCR61_RS18730	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BCR61_RS18755	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BCR61_RS18765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCR61_RS18790	COG1561	YicC-like family, N-terminal region
BCR61_RS18795	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BCR61_RS18810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCR61_RS18840	COG0006	proline dipeptidase activity
BCR61_RS18865	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BCR61_RS18875	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BCR61_RS18885	COG2912	Transglutaminase-like superfamily
BCR61_RS18890	COG1773	rubredoxin
BCR61_RS18895	COG0352	thiamine-phosphate diphosphorylase activity
BCR61_RS18965	COG0281	malic enzyme
BCR61_RS18965	COG0280	phosphate acetyltransferase
BCR61_RS18985	COG4191	Histidine kinase
BCR61_RS19000	COG0583	DNA-binding transcription factor activity
BCR61_RS19020	COG2197	response regulator
BCR61_RS19030	COG0642	Histidine kinase
BCR61_RS19050	COG2851	Citrate transporter
BCR61_RS19055	COG1028	Short-chain dehydrogenase reductase Sdr
BCR61_RS19060	COG1609	Transcriptional regulator
BCR61_RS19070	COG2211	Major facilitator Superfamily
BCR61_RS19095	COG1162	GTPase activity
BCR61_RS19120	COG0726	polysaccharide deacetylase
BCR61_RS19125	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BCR61_RS19160	COG3039	Transposase
BCR61_RS19170	COG3039	Transposase
BCR61_RS19220	COG0242	peptide deformylase activity
BCR61_RS19240	COG0714	Associated with various cellular activities
BCR61_RS19260	COG0537	adenosine 5'-monophosphoramidase activity
BCR61_RS19290	COG0314	molybdopterin synthase activity
BCR61_RS19295	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BCR61_RS19300	COG0315	cyclic pyranopterin monophosphate synthase activity
BCR61_RS19310	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BCR61_RS19315	COG1234	tRNA 3'-trailer cleavage
BCR61_RS19320	COG3642	lipopolysaccharide core region biosynthetic process
BCR61_RS19325	COG0859	PFAM glycosyl transferase family 9
BCR61_RS19335	COG0582	viral genome integration into host DNA
BCR61_RS19390	COG0631	protein serine/threonine phosphatase activity
BCR61_RS19400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCR61_RS19430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCR61_RS19470	COG0544	peptidyl-prolyl cis-trans isomerase activity
BCR61_RS19525	COG0473	3-isopropylmalate dehydrogenase activity
BCR61_RS19550	COG4783	chaperone-mediated protein folding
BCR61_RS19565	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BCR61_RS19575	COG0438	transferase activity, transferring glycosyl groups
BCR61_RS19580	COG0671	phosphoesterase, PA-phosphatase related
BCR61_RS19585	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCR61_RS19605	COG2833	Protein of unknown function (DUF455)
BCR61_RS19625	COG0285	dihydrofolate synthase activity
BCR61_RS19635	COG0588	phosphoglycerate mutase activity
BCR61_RS19670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BCR61_RS19675	COG4208	sulfate ABC transporter
BCR61_RS19680	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BCR61_RS19685	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BCR61_RS19690	COG0156	8-amino-7-oxononanoate synthase activity
BCR61_RS19720	COG0604	alcohol dehydrogenase
BCR61_RS19725	COG1902	pentaerythritol trinitrate reductase activity
BCR61_RS19725	COG0446	pyridine nucleotide-disulphide oxidoreductase
BCR61_RS19825	COG0697	spore germination
BCR61_RS19855	COG3386	PFAM SMP-30 Gluconolaconase
BCR61_RS19875	COG1024	Enoyl-CoA hydratase
BCR61_RS19885	COG0318	PFAM AMP-dependent synthetase and ligase
BCR61_RS19890	COG0583	DNA-binding transcription factor activity
BCR61_RS19930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCR61_RS19935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCR61_RS19945	COG2096	Adenosyltransferase
BCR61_RS19950	COG0123	including yeast histone deacetylase and acetoin utilization protein
BCR61_RS19965	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BCR61_RS19975	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BCR61_RS19980	COG2967	ApaG domain
BCR61_RS20005	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BCR61_RS20025	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BCR61_RS20045	COG0642	Histidine kinase
BCR61_RS20060	COG4181	ATPase activity
BCR61_RS20075	COG2175	clavaminate synthase activity
BCR61_RS20130	COG0667	Aldo Keto reductase
BCR61_RS20140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCR61_RS20145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCR61_RS20165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCR61_RS20180	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BCR61_RS20235	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BCR61_RS20240	COG2226	methyltransferase
BCR61_RS20295	COG0604	alcohol dehydrogenase
BCR61_RS20295	COG1028	Short-chain dehydrogenase reductase Sdr
BCR61_RS20295	COG3321	synthase
BCR61_RS20310	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BCR61_RS20325	COG0494	nUDIX hydrolase
BCR61_RS20340	COG1388	LysM domain
BCR61_RS20340	COG4942	peptidase
BCR61_RS20350	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BCR61_RS20365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BCR61_RS20370	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCR61_RS20375	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BCR61_RS20390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCR61_RS20395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCR61_RS20410	COG3116	cell division
BCR61_RS20415	COG0275	rRNA processing
BCR61_RS20450	COG0792	nuclease activity
BCR61_RS20455	COG1988	membrane-bound metal-dependent
BCR61_RS20460	COG0277	FAD linked oxidase domain protein
BCR61_RS20465	COG0745	RESPONSE REGULATOR receiver
BCR61_RS20470	COG2205	protein histidine kinase activity
BCR61_RS20480	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BCR61_RS20485	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BCR61_RS20510	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BCR61_RS20515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCR61_RS20520	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BCR61_RS20540	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCR61_RS20540	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCR61_RS20560	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BCR61_RS20580	COG0488	(ABC) transporter
BCR61_RS20635	COG2205	protein histidine kinase activity
BCR61_RS20690	COG2205	protein histidine kinase activity
BCR61_RS20705	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BCR61_RS20740	COG3039	Transposase
BCR61_RS20770	COG3039	Transposase
BCR61_RS20870	COG1649	PFAM Uncharacterised BCR, COG1649
BCR61_RS20870	COG0726	polysaccharide deacetylase
BCR61_RS20875	COG1215	transferase activity, transferring glycosyl groups
BCR61_RS20885	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BCR61_RS20890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCR61_RS20895	COG1609	Transcriptional regulator
BCR61_RS20905	COG2188	Transcriptional regulator
BCR61_RS20920	COG3250	beta-galactosidase activity
BCR61_RS20970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BCR61_RS20975	COG4191	Histidine kinase
BCR61_RS20980	COG0784	Response regulator, receiver
BCR61_RS20985	COG4251	negative regulation of phosphorylation
BCR61_RS20990	COG2823	Periplasmic or secreted lipoprotein
BCR61_RS20995	COG0673	inositol 2-dehydrogenase activity
BCR61_RS21000	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BCR61_RS21035	COG1051	belongs to the nudix hydrolase family
BCR61_RS21035	COG1056	cytidyltransferase-related domain
BCR61_RS21060	COG2921	Belongs to the UPF0250 family
BCR61_RS21075	COG1686	Belongs to the peptidase S11 family
BCR61_RS21085	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BCR61_RS21090	COG2951	lytic endotransglycosylase activity
BCR61_RS21160	COG0772	Belongs to the SEDS family
BCR61_RS21175	COG1792	Involved in formation and maintenance of cell shape
BCR61_RS21180	COG1077	Cell shape determining protein MreB Mrl
BCR61_RS21185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCR61_RS21235	COG2199	diguanylate cyclase activity
BCR61_RS21240	COG0308	aminopeptidase N
BCR61_RS21270	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BCR61_RS21300	COG0436	Aminotransferase
BCR61_RS21335	COG1505	serine-type exopeptidase activity
BCR61_RS21360	COG0181	hydroxymethylbilane synthase activity
BCR61_RS21370	COG3275	phosphorelay sensor kinase activity
BCR61_RS21415	COG0659	secondary active sulfate transmembrane transporter activity
BCR61_RS21420	COG5297	Belongs to the glycosyl hydrolase family 6
BCR61_RS21420	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BCR61_RS21495	COG0598	Magnesium transport protein CorA
BCR61_RS21505	COG1113	amino acid transport
BCR61_RS21515	COG5297	Belongs to the glycosyl hydrolase family 6
BCR61_RS21520	COG4305	rare lipoprotein A
BCR61_RS21525	COG0697	spore germination
BCR61_RS21585	COG4221	oxidoreductase activity
BCR61_RS21615	COG0456	acetyltransferase
BCR61_RS21625	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BCR61_RS21670	COG2111	Na H antiporter
BCR61_RS21670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCR61_RS21675	COG1006	Multisubunit Na H antiporter MnhC subunit
BCR61_RS21680	COG0651	ATP synthesis coupled electron transport
BCR61_RS21690	COG2212	antiporter activity
BCR61_RS21695	COG1320	monovalent cation:proton antiporter activity
BCR61_RS21705	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BCR61_RS21725	COG3104	oligopeptide transport
BCR61_RS21730	COG3483	tryptophan 2,3-dioxygenase activity
BCR61_RS21740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCR61_RS21780	COG0183	Belongs to the thiolase family
BCR61_RS21850	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BCR61_RS21855	COG3023	N-Acetylmuramoyl-L-alanine amidase
BCR61_RS21865	COG4948	Mandelate Racemase Muconate Lactonizing
BCR61_RS21895	COG0531	amino acid
BCR61_RS21920	COG4682	membrane
BCR61_RS21925	COG2133	pyrroloquinoline quinone binding
BCR61_RS21970	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCR61_RS21975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BCR61_RS21985	COG1610	YqeY-like protein
BCR61_RS22000	COG1295	ribonuclease BN
BCR61_RS22005	COG0358	DNA primase activity
BCR61_RS22070	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BCR61_RS22085	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BCR61_RS22135	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BCR61_RS22140	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BCR61_RS22145	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BCR61_RS22155	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BCR61_RS22160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCR61_RS22170	COG0134	indole-3-glycerol-phosphate synthase activity
BCR61_RS22175	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCR61_RS22250	COG3039	Transposase
BCR61_RS22270	COG3039	Transposase
BCR61_RS22300	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BCR61_RS22300	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BCR61_RS22310	COG1473	amidohydrolase
BCR61_RS22315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCR61_RS22320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCR61_RS22335	COG5383	Protein conserved in bacteria
BCR61_RS22375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCR61_RS22380	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BCR61_RS22395	COG0028	Belongs to the TPP enzyme family
BCR61_RS22405	COG4191	Histidine kinase
BCR61_RS22430	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BCR61_RS22445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCR61_RS22450	COG3177	Filamentation induced by cAMP protein fic
BCR61_RS22465	COG0596	Alpha beta hydrolase
BCR61_RS22470	COG0727	PFAM Uncharacterised protein family (UPF0153)
BCR61_RS22475	COG0318	PFAM AMP-dependent synthetase and ligase
BCR61_RS22480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCR61_RS22535	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCR61_RS22545	COG0129	dihydroxy-acid dehydratase activity
BCR61_RS22570	COG3039	Transposase
BCR61_RS22580	COG0408	coproporphyrinogen oxidase activity
BCR61_RS22630	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BCR61_RS22695	COG2353	YceI-like domain
BCR61_RS22725	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BCR61_RS22740	COG3386	PFAM SMP-30 Gluconolaconase
BCR61_RS22780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BCR61_RS22795	COG4771	TonB-dependent receptor
BCR61_RS22805	COG0459	protein refolding
BCR61_RS22830	COG1252	NADH dehydrogenase
BCR61_RS22840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCR61_RS22845	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BCR61_RS22850	COG3437	response regulator, receiver
BCR61_RS22855	COG2177	Part of the ABC transporter FtsEX involved in
BCR61_RS22860	COG2884	Cell division ATP-binding protein ftsE
BCR61_RS22870	COG3118	belongs to the thioredoxin family
BCR61_RS22875	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BCR61_RS22890	COG0729	surface antigen
BCR61_RS22895	COG2911	Protein conserved in bacteria
BCR61_RS22930	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCR61_RS22945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCR61_RS23005	COG1733	regulation of RNA biosynthetic process
BCR61_RS23010	COG0702	epimerase
BCR61_RS23045	COG0583	DNA-binding transcription factor activity
BCR61_RS23050	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BCR61_RS23070	COG0745	RESPONSE REGULATOR receiver
BCR61_RS23100	COG1902	pentaerythritol trinitrate reductase activity
BCR61_RS23105	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BCR61_RS23115	COG2814	Major facilitator Superfamily
BCR61_RS23120	COG0583	DNA-binding transcription factor activity
BCR61_RS23140	COG0084	hydrolase, TatD family'
BCR61_RS23185	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BCR61_RS23205	COG2072	flavoprotein involved in K transport
BCR61_RS23265	COG4770	biotin carboxylase activity
BCR61_RS23270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BCR61_RS23275	COG1960	acyl-CoA dehydrogenase activity
BCR61_RS23330	COG0523	cobalamin synthesis protein
BCR61_RS23340	COG0697	spore germination
BCR61_RS23350	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BCR61_RS23365	COG4771	TonB-dependent receptor
BCR61_RS23370	COG0457	Tetratricopeptide repeat
BCR61_RS23380	COG0752	glycyl-tRNA synthetase alpha subunit
BCR61_RS23385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCR61_RS23410	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCR61_RS23410	COG0519	Catalyzes the synthesis of GMP from XMP
BCR61_RS23420	COG0805	protein transport
BCR61_RS23430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BCR61_RS23440	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BCR61_RS23470	COG2974	May be involved in recombination
BCR61_RS23475	COG0037	tRNA processing
BCR61_RS23495	COG3661	Belongs to the glycosyl hydrolase 67 family
BCR61_RS23505	COG4948	Mandelate Racemase Muconate Lactonizing
BCR61_RS23515	COG1472	Belongs to the glycosyl hydrolase 3 family
BCR61_RS23520	COG0246	Mannitol dehydrogenase
BCR61_RS23545	COG3693	PFAM glycoside hydrolase, family 10
BCR61_RS23570	COG2211	Major facilitator Superfamily
BCR61_RS23620	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BCR61_RS23660	COG1846	Transcriptional regulator
BCR61_RS23665	COG1764	response to oxidative stress
BCR61_RS23755	COG3549	Plasmid maintenance system killer
BCR61_RS23765	COG1074	ATP-dependent DNA helicase activity
BCR61_RS23770	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BCR61_RS23810	COG2032	superoxide dismutase activity
BCR61_RS23815	COG2032	superoxide dismutase activity
BCR61_RS23820	COG2204	response regulator
BCR61_RS23825	COG3852	Histidine kinase
BCR61_RS23830	COG0004	ammonium transporteR
BCR61_RS23835	COG0347	Belongs to the P(II) protein family
BCR61_RS23840	COG0174	glutamine synthetase
BCR61_RS23845	COG1968	undecaprenyl-diphosphatase activity
BCR61_RS23890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCR61_RS23900	COG2062	phosphohistidine phosphatase, SixA
BCR61_RS23905	COG0489	protein tyrosine kinase activity
BCR61_RS23925	COG1396	sequence-specific DNA binding
BCR61_RS23930	COG3550	peptidyl-serine autophosphorylation
BCR61_RS23935	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BCR61_RS23940	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BCR61_RS23955	COG0517	IMP dehydrogenase activity
BCR61_RS23955	COG1125	glycine betaine transport
BCR61_RS23970	COG1119	ATPase activity
BCR61_RS23980	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCR61_RS23995	COG3039	Transposase
BCR61_RS24020	COG0656	L-ascorbic acid biosynthetic process
BCR61_RS24025	COG2130	NADP-dependent
BCR61_RS24030	COG0667	Aldo Keto reductase
BCR61_RS24040	COG1187	pseudouridine synthase activity
BCR61_RS24055	COG1643	Atp-dependent helicase
BCR61_RS24060	COG4807	Protein conserved in bacteria
BCR61_RS24065	COG4948	Mandelate Racemase Muconate Lactonizing
BCR61_RS24075	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCR61_RS24080	COG1028	Short-chain dehydrogenase reductase Sdr
BCR61_RS24100	COG3507	Belongs to the glycosyl hydrolase 43 family
BCR61_RS24145	COG3162	membrane
BCR61_RS24150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCR61_RS24165	COG0708	Exodeoxyribonuclease III
BCR61_RS24180	COG2091	lysine biosynthetic process via aminoadipic acid
BCR61_RS24190	COG3540	Alkaline phosphatase
BCR61_RS24195	COG0357	Ribosomal RNA small subunit methyltransferase G
BCR61_RS24225	COG2159	amidohydrolase
BCR61_RS24240	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BCR61_RS24245	COG0583	DNA-binding transcription factor activity
BCR61_RS24250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCR61_RS24270	COG0210	DNA helicase
BCR61_RS24285	COG0531	amino acid
BCR61_RS24295	COG1322	Protein conserved in bacteria
BCR61_RS24305	COG0386	Belongs to the glutathione peroxidase family
BCR61_RS24370	COG0793	Belongs to the peptidase S41A family
BCR61_RS24375	COG4942	peptidase
BCR61_RS24385	COG2234	aminopeptidase activity
BCR61_RS24435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BCR61_RS24440	COG0302	gtp cyclohydrolase
BCR61_RS24465	COG0477	Major facilitator Superfamily
BCR61_RS24535	COG1929	Belongs to the glycerate kinase type-1 family
BCR61_RS24540	COG2271	Major facilitator Superfamily
BCR61_RS24555	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BCR61_RS24565	COG0861	Integral membrane protein TerC family
BCR61_RS24580	COG0584	glycerophosphoryl diester phosphodiesterase
BCR61_RS24590	COG0671	phosphoesterase, PA-phosphatase related
BCR61_RS24595	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BCR61_RS24600	COG0726	polysaccharide deacetylase
BCR61_RS24705	COG2948	multi-organism process
BCR61_RS24710	COG3504	Conjugal transfer protein
BCR61_RS24845	COG3039	Transposase
BCR61_RS24870	COG0489	protein tyrosine kinase activity