locus-tag	class	description
IXO792_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IXO792_RS00020	COG0187	DNA topoisomerase II activity
IXO792_RS00030	COG0501	Belongs to the peptidase M48B family
IXO792_RS00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IXO792_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO792_RS00080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IXO792_RS00090	COG4772	TonB-dependent receptor
IXO792_RS00110	COG1304	FMN binding
IXO792_RS00140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO792_RS00225	COG2826	transposase and inactivated derivatives, IS30 family
IXO792_RS00250	COG3039	Transposase
IXO792_RS00260	COG1090	epimerase
IXO792_RS00280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IXO792_RS00390	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IXO792_RS00465	COG1511	domain protein
IXO792_RS00465	COG3264	Mechanosensitive ion channel
IXO792_RS00480	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IXO792_RS00485	COG2354	Protein conserved in bacteria
IXO792_RS00490	COG1649	PFAM Uncharacterised BCR, COG1649
IXO792_RS00510	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IXO792_RS00535	COG0702	epimerase
IXO792_RS00550	COG1858	cytochrome C peroxidase
IXO792_RS00625	COG0513	Belongs to the DEAD box helicase family
IXO792_RS00630	COG3039	Transposase
IXO792_RS00675	COG1136	(ABC) transporter
IXO792_RS00705	COG1136	(ABC) transporter
IXO792_RS00745	COG1272	protein, Hemolysin III
IXO792_RS00750	COG1111	helicase
IXO792_RS00750	COG1205	dead DEAH box helicase
IXO792_RS00810	COG0067	glutamate synthase
IXO792_RS00810	COG0069	glutamate synthase activity
IXO792_RS00810	COG0070	glutamate synthase
IXO792_RS00815	COG0493	'glutamate synthase
IXO792_RS00860	COG1609	Transcriptional regulator
IXO792_RS00885	COG0366	Alpha amylase catalytic
IXO792_RS00890	COG0366	Alpha amylase catalytic
IXO792_RS00930	COG0606	chelatase, subunit chli
IXO792_RS00970	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IXO792_RS00975	COG1166	arginine decarboxylase activity
IXO792_RS01060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IXO792_RS01085	COG1028	Short-chain dehydrogenase reductase Sdr
IXO792_RS01110	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
IXO792_RS01125	COG0210	DNA helicase
IXO792_RS01140	COG3132	Protein of unknown function, DUF480
IXO792_RS01145	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
IXO792_RS01150	COG0284	orotidine-5'-phosphate decarboxylase activity
IXO792_RS01185	COG2937	Belongs to the GPAT DAPAT family
IXO792_RS01190	COG0604	alcohol dehydrogenase
IXO792_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
IXO792_RS01190	COG3321	synthase
IXO792_RS01225	COG3186	Phenylalanine-4-hydroxylase
IXO792_RS01230	COG1522	sequence-specific DNA binding
IXO792_RS01275	COG1064	alcohol dehydrogenase
IXO792_RS01280	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO792_RS01285	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO792_RS01295	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO792_RS01315	COG0676	glucose-6-phosphate 1-epimerase activity
IXO792_RS01380	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IXO792_RS01400	COG2853	Lipoprotein
IXO792_RS01415	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IXO792_RS01420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IXO792_RS01425	COG1127	ABC transporter
IXO792_RS01500	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO792_RS01505	COG3265	gluconokinase activity
IXO792_RS01510	COG2211	Major facilitator Superfamily
IXO792_RS01515	COG3459	Glycosyltransferase 36 associated
IXO792_RS01525	COG2205	protein histidine kinase activity
IXO792_RS01535	COG1414	Transcriptional regulator
IXO792_RS01540	COG0738	Major facilitator superfamily
IXO792_RS01545	COG3254	rhamnose metabolic process
IXO792_RS01575	COG0339	signal peptide processing
IXO792_RS01605	COG0564	pseudouridine synthase activity
IXO792_RS01615	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IXO792_RS01625	COG1181	Belongs to the D-alanine--D-alanine ligase family
IXO792_RS01665	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IXO792_RS01675	COG0842	Transport permease protein
IXO792_RS01680	COG1131	(ABC) transporter
IXO792_RS01705	COG1476	TRANSCRIPTIONal
IXO792_RS01715	COG4555	ABC transporter
IXO792_RS01750	COG0625	glutathione transferase activity
IXO792_RS01795	COG0583	DNA-binding transcription factor activity
IXO792_RS01835	COG1199	ATP-dependent helicase activity
IXO792_RS01870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IXO792_RS01900	COG3228	Belongs to the MtfA family
IXO792_RS01910	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IXO792_RS01910	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IXO792_RS01915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IXO792_RS01930	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IXO792_RS01965	COG3237	CsbD-like
IXO792_RS01970	COG0180	Tryptophanyl-tRNA synthetase
IXO792_RS01975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IXO792_RS02020	COG0753	catalase activity
IXO792_RS02025	COG1595	DNA-templated transcription, initiation
IXO792_RS02035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IXO792_RS02045	COG0628	permease
IXO792_RS02055	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IXO792_RS02060	COG1040	competence protein
IXO792_RS02065	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IXO792_RS02070	COG0156	8-amino-7-oxononanoate synthase activity
IXO792_RS02080	COG1028	Short-chain dehydrogenase reductase Sdr
IXO792_RS02095	COG0463	Glycosyl transferase, family 2
IXO792_RS02105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IXO792_RS02110	COG3100	YcgL domain-containing protein
IXO792_RS02125	COG3387	PFAM Glycoside hydrolase 15-related
IXO792_RS02130	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IXO792_RS02135	COG3039	Transposase
IXO792_RS02200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IXO792_RS02215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IXO792_RS02220	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IXO792_RS02230	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
IXO792_RS02235	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IXO792_RS02240	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IXO792_RS02290	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IXO792_RS02305	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
IXO792_RS02370	COG0358	DNA primase activity
IXO792_RS02375	COG1295	ribonuclease BN
IXO792_RS02385	COG1610	YqeY-like protein
IXO792_RS02395	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IXO792_RS02400	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IXO792_RS02445	COG2133	pyrroloquinoline quinone binding
IXO792_RS02450	COG4682	membrane
IXO792_RS02475	COG0531	amino acid
IXO792_RS02500	COG4948	Mandelate Racemase Muconate Lactonizing
IXO792_RS02510	COG3023	N-Acetylmuramoyl-L-alanine amidase
IXO792_RS02515	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IXO792_RS02585	COG0183	Belongs to the thiolase family
IXO792_RS02635	COG3483	tryptophan 2,3-dioxygenase activity
IXO792_RS02640	COG3104	oligopeptide transport
IXO792_RS02670	COG1320	monovalent cation:proton antiporter activity
IXO792_RS02675	COG2212	antiporter activity
IXO792_RS02685	COG0651	ATP synthesis coupled electron transport
IXO792_RS02690	COG1006	Multisubunit Na H antiporter MnhC subunit
IXO792_RS02695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IXO792_RS02695	COG2111	Na H antiporter
IXO792_RS02740	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IXO792_RS02750	COG0456	acetyltransferase
IXO792_RS02780	COG4221	oxidoreductase activity
IXO792_RS02840	COG0697	spore germination
IXO792_RS02845	COG4305	rare lipoprotein A
IXO792_RS02850	COG5297	Belongs to the glycosyl hydrolase family 6
IXO792_RS02860	COG1113	amino acid transport
IXO792_RS02870	COG0598	Magnesium transport protein CorA
IXO792_RS02940	COG5297	Belongs to the glycosyl hydrolase family 6
IXO792_RS02940	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO792_RS02945	COG0659	secondary active sulfate transmembrane transporter activity
IXO792_RS02980	COG3275	phosphorelay sensor kinase activity
IXO792_RS02990	COG0181	hydroxymethylbilane synthase activity
IXO792_RS03015	COG1505	serine-type exopeptidase activity
IXO792_RS03030	COG3039	Transposase
IXO792_RS03035	COG0436	Aminotransferase
IXO792_RS03065	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IXO792_RS03095	COG0308	aminopeptidase N
IXO792_RS03100	COG2199	diguanylate cyclase activity
IXO792_RS03150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO792_RS03155	COG1077	Cell shape determining protein MreB Mrl
IXO792_RS03160	COG1792	Involved in formation and maintenance of cell shape
IXO792_RS03175	COG0772	Belongs to the SEDS family
IXO792_RS03210	COG2951	lytic endotransglycosylase activity
IXO792_RS03215	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IXO792_RS03220	COG1686	Belongs to the peptidase S11 family
IXO792_RS03235	COG2921	Belongs to the UPF0250 family
IXO792_RS03260	COG1056	cytidyltransferase-related domain
IXO792_RS03260	COG1051	belongs to the nudix hydrolase family
IXO792_RS03295	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IXO792_RS03300	COG0673	inositol 2-dehydrogenase activity
IXO792_RS03305	COG2823	Periplasmic or secreted lipoprotein
IXO792_RS03310	COG4251	negative regulation of phosphorylation
IXO792_RS03315	COG0784	Response regulator, receiver
IXO792_RS03320	COG4191	Histidine kinase
IXO792_RS03325	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IXO792_RS03375	COG3250	beta-galactosidase activity
IXO792_RS03390	COG2188	Transcriptional regulator
IXO792_RS03400	COG1609	Transcriptional regulator
IXO792_RS03405	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IXO792_RS03410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IXO792_RS03420	COG1215	transferase activity, transferring glycosyl groups
IXO792_RS03425	COG0726	polysaccharide deacetylase
IXO792_RS03425	COG1649	PFAM Uncharacterised BCR, COG1649
IXO792_RS03505	COG3039	Transposase
IXO792_RS03510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IXO792_RS03515	COG3039	Transposase
IXO792_RS03550	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IXO792_RS03595	COG2205	protein histidine kinase activity
IXO792_RS03625	COG3791	Glutathione-dependent formaldehyde-activating
IXO792_RS03640	COG3039	Transposase
IXO792_RS03655	COG0488	(ABC) transporter
IXO792_RS03675	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IXO792_RS03695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IXO792_RS03695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IXO792_RS03715	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IXO792_RS03720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IXO792_RS03725	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IXO792_RS03745	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IXO792_RS03750	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IXO792_RS03760	COG2205	protein histidine kinase activity
IXO792_RS03765	COG0745	RESPONSE REGULATOR receiver
IXO792_RS03770	COG0277	FAD linked oxidase domain protein
IXO792_RS03775	COG1988	membrane-bound metal-dependent
IXO792_RS03780	COG0792	nuclease activity
IXO792_RS03815	COG0275	rRNA processing
IXO792_RS03820	COG3116	cell division
IXO792_RS03835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IXO792_RS03840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IXO792_RS03855	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IXO792_RS03860	COG1181	Belongs to the D-alanine--D-alanine ligase family
IXO792_RS03865	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IXO792_RS03880	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IXO792_RS03890	COG1388	LysM domain
IXO792_RS03890	COG4942	peptidase
IXO792_RS03895	COG0653	protein targeting
IXO792_RS03905	COG0494	nUDIX hydrolase
IXO792_RS03920	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IXO792_RS03930	COG1028	Short-chain dehydrogenase reductase Sdr
IXO792_RS03930	COG3321	synthase
IXO792_RS03930	COG0604	alcohol dehydrogenase
IXO792_RS03980	COG2226	methyltransferase
IXO792_RS03985	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IXO792_RS04025	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IXO792_RS04030	COG3039	Transposase
IXO792_RS04045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IXO792_RS04055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO792_RS04060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IXO792_RS04070	COG3039	Transposase
IXO792_RS04090	COG0667	Aldo Keto reductase
IXO792_RS04135	COG1116	anion transmembrane transporter activity
IXO792_RS04140	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IXO792_RS04150	COG2175	clavaminate synthase activity
IXO792_RS04160	COG4181	ATPase activity
IXO792_RS04175	COG0642	Histidine kinase
IXO792_RS04195	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IXO792_RS04215	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IXO792_RS04240	COG2967	ApaG domain
IXO792_RS04245	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IXO792_RS04255	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IXO792_RS04270	COG0123	including yeast histone deacetylase and acetoin utilization protein
IXO792_RS04275	COG2096	Adenosyltransferase
IXO792_RS04285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IXO792_RS04290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IXO792_RS04330	COG0583	DNA-binding transcription factor activity
IXO792_RS04335	COG0318	PFAM AMP-dependent synthetase and ligase
IXO792_RS04345	COG1024	Enoyl-CoA hydratase
IXO792_RS04365	COG3386	PFAM SMP-30 Gluconolaconase
IXO792_RS04485	COG0446	pyridine nucleotide-disulphide oxidoreductase
IXO792_RS04485	COG1902	pentaerythritol trinitrate reductase activity
IXO792_RS04490	COG0604	alcohol dehydrogenase
IXO792_RS04515	COG0156	8-amino-7-oxononanoate synthase activity
IXO792_RS04520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IXO792_RS04525	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IXO792_RS04530	COG4208	sulfate ABC transporter
IXO792_RS04535	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IXO792_RS04565	COG0588	phosphoglycerate mutase activity
IXO792_RS04575	COG0285	dihydrofolate synthase activity
IXO792_RS04595	COG2833	Protein of unknown function (DUF455)
IXO792_RS04615	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IXO792_RS04620	COG0671	phosphoesterase, PA-phosphatase related
IXO792_RS04625	COG0438	transferase activity, transferring glycosyl groups
IXO792_RS04635	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IXO792_RS04650	COG4783	chaperone-mediated protein folding
IXO792_RS04675	COG0473	3-isopropylmalate dehydrogenase activity
IXO792_RS04725	COG0544	peptidyl-prolyl cis-trans isomerase activity
IXO792_RS04765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IXO792_RS04790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IXO792_RS04800	COG0631	protein serine/threonine phosphatase activity
IXO792_RS04870	COG0582	viral genome integration into host DNA
IXO792_RS04880	COG0859	PFAM glycosyl transferase family 9
IXO792_RS04885	COG3642	lipopolysaccharide core region biosynthetic process
IXO792_RS04890	COG1234	tRNA 3'-trailer cleavage
IXO792_RS04895	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IXO792_RS04905	COG0315	cyclic pyranopterin monophosphate synthase activity
IXO792_RS04910	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IXO792_RS04915	COG0314	molybdopterin synthase activity
IXO792_RS04945	COG0537	adenosine 5'-monophosphoramidase activity
IXO792_RS04965	COG0714	Associated with various cellular activities
IXO792_RS04985	COG0242	peptide deformylase activity
IXO792_RS05065	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IXO792_RS05070	COG0726	polysaccharide deacetylase
IXO792_RS05095	COG1162	GTPase activity
IXO792_RS05120	COG2211	Major facilitator Superfamily
IXO792_RS05130	COG1609	Transcriptional regulator
IXO792_RS05135	COG1028	Short-chain dehydrogenase reductase Sdr
IXO792_RS05140	COG2851	Citrate transporter
IXO792_RS05155	COG0642	Histidine kinase
IXO792_RS05165	COG2197	response regulator
IXO792_RS05185	COG0583	DNA-binding transcription factor activity
IXO792_RS05200	COG4191	Histidine kinase
IXO792_RS05220	COG0280	phosphate acetyltransferase
IXO792_RS05220	COG0281	malic enzyme
IXO792_RS05285	COG0352	thiamine-phosphate diphosphorylase activity
IXO792_RS05290	COG1773	rubredoxin
IXO792_RS05295	COG2912	Transglutaminase-like superfamily
IXO792_RS05305	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IXO792_RS05315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IXO792_RS05340	COG0006	proline dipeptidase activity
IXO792_RS05375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IXO792_RS05390	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IXO792_RS05395	COG1561	YicC-like family, N-terminal region
IXO792_RS05420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IXO792_RS05430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IXO792_RS05455	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IXO792_RS05500	COG0714	Associated with various cellular activities
IXO792_RS05520	COG2304	oxidoreductase activity
IXO792_RS05540	COG1301	dicarboxylic acid transport
IXO792_RS05545	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IXO792_RS05555	COG0739	heme binding
IXO792_RS05560	COG1376	ErfK ybiS ycfS ynhG family protein
IXO792_RS05585	COG1022	Amp-dependent synthetase and ligase
IXO792_RS05600	COG1028	Short-chain dehydrogenase reductase Sdr
IXO792_RS05615	COG0642	Histidine kinase
IXO792_RS05635	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IXO792_RS05640	COG4149	molybdate abc transporter
IXO792_RS05645	COG0725	ABC transporter, periplasmic molybdate-binding protein
IXO792_RS05650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IXO792_RS05650	COG3453	Protein conserved in bacteria
IXO792_RS05690	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IXO792_RS05715	COG2205	protein histidine kinase activity
IXO792_RS05720	COG0745	RESPONSE REGULATOR receiver
IXO792_RS05765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IXO792_RS05770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IXO792_RS05820	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IXO792_RS05900	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IXO792_RS05910	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IXO792_RS05915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IXO792_RS05930	COG1842	Phage shock protein A
IXO792_RS05955	COG0754	glutathionylspermidine amidase activity
IXO792_RS06015	COG0531	amino acid
IXO792_RS06020	COG2197	response regulator
IXO792_RS06035	COG1113	amino acid transport
IXO792_RS06050	COG1271	oxidase subunit
IXO792_RS06055	COG1294	oxidase, subunit
IXO792_RS06065	COG2239	Acts as a magnesium transporter
IXO792_RS06070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IXO792_RS06075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO792_RS06090	COG1660	Displays ATPase and GTPase activities
IXO792_RS06095	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IXO792_RS06100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO792_RS06115	COG1137	ATPase activity
IXO792_RS06120	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IXO792_RS06130	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IXO792_RS06140	COG0271	Belongs to the BolA IbaG family
IXO792_RS06145	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IXO792_RS06165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IXO792_RS06180	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IXO792_RS06190	COG0628	permease
IXO792_RS06200	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IXO792_RS06205	COG3178	'Phosphotransferase
IXO792_RS06220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO792_RS06225	COG1555	photosystem II stabilization
IXO792_RS06275	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IXO792_RS06285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IXO792_RS06305	COG0228	four-way junction DNA binding
IXO792_RS06310	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IXO792_RS06315	COG0336	Belongs to the RNA methyltransferase TrmD family
IXO792_RS06330	COG0534	Mate efflux family protein
IXO792_RS06365	COG0542	response to heat
IXO792_RS06400	COG4206	TonB-dependent receptor
IXO792_RS06465	COG0019	diaminopimelate decarboxylase activity
IXO792_RS06475	COG2814	Major facilitator Superfamily
IXO792_RS06480	COG4264	IucA IucC family
IXO792_RS06490	COG4772	TonB-dependent receptor
IXO792_RS06505	COG4651	solute:proton antiporter activity
IXO792_RS06505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IXO792_RS06545	COG0488	(ABC) transporter
IXO792_RS06570	COG0657	acetylesterase activity
IXO792_RS06570	COG2755	lipolytic protein G-D-S-L family
IXO792_RS06615	COG2207	Transcriptional regulator
IXO792_RS06620	COG0326	Molecular chaperone. Has ATPase activity
IXO792_RS06645	COG3328	transposase activity
IXO792_RS06650	COG0174	glutamine synthetase
IXO792_RS06655	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IXO792_RS06665	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IXO792_RS06680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IXO792_RS06705	COG2146	nitrite reductase [NAD(P)H] activity
IXO792_RS06715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IXO792_RS06720	COG0719	Fe-S assembly protein
IXO792_RS06725	COG0396	ATPase activity
IXO792_RS06730	COG0719	Fe-S assembly protein
IXO792_RS06735	COG1959	2 iron, 2 sulfur cluster binding
IXO792_RS06795	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IXO792_RS06820	COG0519	Catalyzes the synthesis of GMP from XMP
IXO792_RS06835	COG1678	Uncharacterized ACR, COG1678
IXO792_RS06840	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IXO792_RS06870	COG1764	response to oxidative stress
IXO792_RS06880	COG0384	phenazine biosynthesis protein PhzF
IXO792_RS06890	COG0527	aspartate kinase activity
IXO792_RS06915	COG0142	geranyltranstransferase activity
IXO792_RS06920	COG0629	single-stranded DNA binding
IXO792_RS06925	COG5001	Diguanylate cyclase
IXO792_RS06925	COG3706	GGDEF domain
IXO792_RS06925	COG2203	Gaf domain
IXO792_RS06925	COG4251	negative regulation of phosphorylation
IXO792_RS06955	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IXO792_RS07000	COG2879	small protein
IXO792_RS07005	COG1966	Carbon starvation protein
IXO792_RS07010	COG1741	Belongs to the pirin family
IXO792_RS07055	COG1741	Belongs to the pirin family
IXO792_RS07065	COG1515	deoxyribonuclease V activity
IXO792_RS07070	COG0588	phosphoglycerate mutase activity
IXO792_RS07085	COG3590	peptidase
IXO792_RS07100	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IXO792_RS07105	COG2200	EAL domain
IXO792_RS07105	COG2202	Pas domain
IXO792_RS07105	COG2199	diguanylate cyclase activity
IXO792_RS07110	COG0835	chemotaxis
IXO792_RS07115	COG0840	transmembrane signaling receptor activity
IXO792_RS07120	COG2198	Histidine kinase
IXO792_RS07120	COG0643	Histidine kinase
IXO792_RS07135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IXO792_RS07145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IXO792_RS07235	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IXO792_RS07240	COG0735	belongs to the Fur family
IXO792_RS07300	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IXO792_RS07305	COG0084	hydrolase, TatD family'
IXO792_RS07320	COG1960	acyl-CoA dehydrogenase activity
IXO792_RS07335	COG0367	asparagine synthase
IXO792_RS07345	COG0305	Participates in initiation and elongation during chromosome replication
IXO792_RS07350	COG0415	Belongs to the DNA photolyase family
IXO792_RS07465	COG5001	Diguanylate cyclase
IXO792_RS07465	COG5002	protein histidine kinase activity
IXO792_RS07470	COG1187	pseudouridine synthase activity
IXO792_RS07490	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IXO792_RS07500	COG0475	glutathione-regulated potassium exporter activity
IXO792_RS07505	COG5000	phosphorelay sensor kinase activity
IXO792_RS07505	COG5002	protein histidine kinase activity
IXO792_RS07510	COG0745	RESPONSE REGULATOR receiver
IXO792_RS07540	COG1132	(ABC) transporter
IXO792_RS07570	COG3039	Transposase
IXO792_RS07585	COG3039	Transposase
IXO792_RS07615	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IXO792_RS07625	COG4969	Belongs to the N-Me-Phe pilin family
IXO792_RS07630	COG2194	sulfuric ester hydrolase activity
IXO792_RS07650	COG2184	nucleotidyltransferase activity
IXO792_RS07675	COG0045	succinate-CoA ligase (ADP-forming) activity
IXO792_RS07680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IXO792_RS07690	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IXO792_RS07690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IXO792_RS07695	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO792_RS07700	COG0564	pseudouridine synthase activity
IXO792_RS07725	COG3387	PFAM Glycoside hydrolase 15-related
IXO792_RS07730	COG1877	trehalose-phosphatase activity
IXO792_RS07770	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IXO792_RS07795	COG1946	Acyl-CoA thioesterase
IXO792_RS07810	COG0824	Thioesterase
IXO792_RS07815	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IXO792_RS07825	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IXO792_RS07830	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IXO792_RS07835	COG0268	Binds directly to 16S ribosomal RNA
IXO792_RS07840	COG0728	peptidoglycan biosynthetic process
IXO792_RS07845	COG0196	riboflavin kinase activity
IXO792_RS07855	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IXO792_RS07860	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IXO792_RS07875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IXO792_RS07880	COG1845	cytochrome c oxidase, subunit III
IXO792_RS07885	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IXO792_RS07910	COG3209	COG3209 Rhs family protein
IXO792_RS07925	COG3328	transposase activity
IXO792_RS08040	COG0632	four-way junction helicase activity
IXO792_RS08050	COG2255	four-way junction helicase activity
IXO792_RS08055	COG0824	Thioesterase
IXO792_RS08065	COG0848	biopolymer transport protein
IXO792_RS08080	COG2885	chlorophyll binding
IXO792_RS08090	COG0602	queuosine metabolic process
IXO792_RS08095	COG1187	pseudouridine synthase activity
IXO792_RS08160	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IXO792_RS08340	COG3179	chitinase
IXO792_RS08385	COG4695	Portal protein
IXO792_RS08470	COG0514	ATP-dependent DNA helicase (RecQ)
IXO792_RS08475	COG0783	Belongs to the Dps family
IXO792_RS08480	COG1643	Atp-dependent helicase
IXO792_RS08510	COG0535	radical SAM domain protein
IXO792_RS08515	COG0535	radical SAM domain protein
IXO792_RS08535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IXO792_RS08545	COG1215	transferase activity, transferring glycosyl groups
IXO792_RS08550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IXO792_RS08560	COG1199	ATP-dependent helicase activity
IXO792_RS08570	COG1397	ADP-ribosylglycohydrolase
IXO792_RS08580	COG0189	ligase activity
IXO792_RS08595	COG0835	chemotaxis
IXO792_RS08600	COG0840	transmembrane signaling receptor activity
IXO792_RS08605	COG0643	Histidine kinase
IXO792_RS08605	COG0784	Response regulator, receiver
IXO792_RS08605	COG2198	Histidine kinase
IXO792_RS08645	COG2304	oxidoreductase activity
IXO792_RS08650	COG2304	oxidoreductase activity
IXO792_RS08660	COG1446	asparaginase
IXO792_RS08705	COG3537	Alpha-1,2-mannosidase
IXO792_RS08745	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO792_RS08755	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IXO792_RS08765	COG1388	LysM domain
IXO792_RS08765	COG3858	chitin binding
IXO792_RS08780	COG0837	glucose binding
IXO792_RS08785	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IXO792_RS08795	COG0494	nUDIX hydrolase
IXO792_RS08805	COG3956	TIGRFAM MazG family protein
IXO792_RS08820	COG0330	HflC and HflK could
IXO792_RS08835	COG0509	glycine decarboxylation via glycine cleavage system
IXO792_RS08850	COG3039	Transposase
IXO792_RS08870	COG1960	acyl-CoA dehydrogenase activity
IXO792_RS08880	COG1309	transcriptional regulator
IXO792_RS08885	COG4771	TonB-dependent receptor
IXO792_RS08895	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IXO792_RS08905	COG0463	Glycosyl transferase, family 2
IXO792_RS08930	COG1272	protein, Hemolysin III
IXO792_RS08940	COG0739	heme binding
IXO792_RS08945	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO792_RS08950	COG0626	cystathionine gamma-synthase activity
IXO792_RS08960	COG1760	l-serine dehydratase
IXO792_RS08975	COG2353	YceI-like domain
IXO792_RS08985	COG2353	YceI-like domain
IXO792_RS09055	COG1960	acyl-CoA dehydrogenase activity
IXO792_RS09060	COG1024	Enoyl-CoA hydratase
IXO792_RS09085	COG1024	Enoyl-CoA hydratase
IXO792_RS09085	COG1250	3-hydroxyacyl-CoA dehydrogenase
IXO792_RS09100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IXO792_RS09105	COG0481	GTPase activity
IXO792_RS09130	COG1381	Involved in DNA repair and RecF pathway recombination
IXO792_RS09145	COG2954	triphosphatase activity
IXO792_RS09155	COG3039	Transposase
IXO792_RS09160	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IXO792_RS09165	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
IXO792_RS09170	COG3046	protein related to deoxyribodipyrimidine photolyase
IXO792_RS09180	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IXO792_RS09185	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IXO792_RS09190	COG1278	Cold shock
IXO792_RS09215	COG1201	RNA secondary structure unwinding
IXO792_RS09220	COG1793	dna ligase
IXO792_RS09230	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IXO792_RS09230	COG1793	dna ligase
IXO792_RS09260	COG0183	Belongs to the thiolase family
IXO792_RS09295	COG1451	nucleotide metabolic process
IXO792_RS09310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IXO792_RS09345	COG1047	Peptidyl-prolyl cis-trans
IXO792_RS09360	COG2824	Alkylphosphonate utilization operon protein PhnA
IXO792_RS09370	COG1902	pentaerythritol trinitrate reductase activity
IXO792_RS09375	COG2814	Major facilitator Superfamily
IXO792_RS09400	COG3039	Transposase
IXO792_RS09430	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IXO792_RS09430	COG0392	lysyltransferase activity
IXO792_RS09440	COG0251	oxidation-reduction process
IXO792_RS09445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IXO792_RS09460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IXO792_RS09485	COG1595	DNA-templated transcription, initiation
IXO792_RS09505	COG2878	Part of a membrane complex involved in electron transport
IXO792_RS09515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IXO792_RS09515	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IXO792_RS09535	COG0833	amino acid
IXO792_RS09540	COG2040	homocysteine
IXO792_RS09555	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IXO792_RS09595	COG2895	sulfate adenylyltransferase (ATP) activity
IXO792_RS09595	COG0529	Catalyzes the synthesis of activated sulfate
IXO792_RS09645	COG1981	membrane
IXO792_RS09675	COG4771	TonB-dependent receptor
IXO792_RS09685	COG0825	malonyl-CoA metabolic process
IXO792_RS09705	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IXO792_RS09710	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IXO792_RS09730	COG0750	zinc metalloprotease
IXO792_RS09740	COG0575	Belongs to the CDS family
IXO792_RS09750	COG0233	cytoplasmic translational termination
IXO792_RS09765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IXO792_RS09825	COG1393	Belongs to the ArsC family
IXO792_RS09835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO792_RS09840	COG0367	asparagine synthase
IXO792_RS09850	COG4774	siderophore transport
IXO792_RS09890	COG1566	PFAM secretion protein HlyD family protein
IXO792_RS09895	COG2814	Major facilitator Superfamily
IXO792_RS09950	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IXO792_RS09960	COG1960	acyl-CoA dehydrogenase activity
IXO792_RS09975	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IXO792_RS09985	COG2914	Belongs to the UPF0125 (RnfH) family
IXO792_RS09990	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO792_RS10000	COG0497	DNA recombination
IXO792_RS10010	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IXO792_RS10020	COG0484	heat shock protein binding
IXO792_RS10025	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IXO792_RS10030	COG0287	Prephenate dehydrogenase
IXO792_RS10030	COG1605	Chorismate mutase
IXO792_RS10055	COG1132	(ABC) transporter
IXO792_RS10090	COG2850	peptidyl-arginine hydroxylation
IXO792_RS10170	COG1131	(ABC) transporter
IXO792_RS10175	COG1725	Transcriptional regulator
IXO792_RS10185	COG0386	Belongs to the glutathione peroxidase family
IXO792_RS10200	COG2900	Belongs to the SlyX family
IXO792_RS10215	COG1609	Transcriptional regulator
IXO792_RS10225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO792_RS10235	COG0646	methionine synthase
IXO792_RS10235	COG1410	methionine synthase
IXO792_RS10240	COG0646	methionine synthase
IXO792_RS10240	COG1410	methionine synthase
IXO792_RS10245	COG2226	methyltransferase
IXO792_RS10250	COG1960	acyl-CoA dehydrogenase activity
IXO792_RS10275	COG0557	exoribonuclease II activity
IXO792_RS10295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IXO792_RS10305	COG3039	Transposase
IXO792_RS10375	COG3842	ATPase activity
IXO792_RS10395	COG1012	belongs to the aldehyde dehydrogenase family
IXO792_RS10410	COG4535	Mg2 and Co2 transporter CorC
IXO792_RS10430	COG1702	phosphate starvation-inducible protein PhoH
IXO792_RS10455	COG0741	lytic transglycosylase activity
IXO792_RS10460	COG0723	plastoquinol--plastocyanin reductase activity
IXO792_RS10465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IXO792_RS10470	COG2857	Cytochrome c1
IXO792_RS10475	COG0625	glutathione transferase activity
IXO792_RS10480	COG2969	positive regulation of protein catabolic process
IXO792_RS10505	COG2094	Belongs to the DNA glycosylase MPG family
IXO792_RS10515	COG3328	transposase activity
IXO792_RS10600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO792_RS10620	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IXO792_RS10625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IXO792_RS10625	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IXO792_RS10630	COG0802	atpase or kinase
IXO792_RS10635	COG0860	N-Acetylmuramoyl-L-alanine amidase
IXO792_RS10640	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IXO792_RS10660	COG1028	Short-chain dehydrogenase reductase Sdr
IXO792_RS10670	COG0501	Belongs to the peptidase M48B family
IXO792_RS10680	COG2081	HI0933 family
IXO792_RS10685	COG4681	YaeQ
IXO792_RS10690	COG1671	Belongs to the UPF0178 family
IXO792_RS10700	COG0625	glutathione transferase activity
IXO792_RS10710	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IXO792_RS10715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IXO792_RS10720	COG0513	Belongs to the DEAD box helicase family
IXO792_RS10725	COG0488	(ABC) transporter
IXO792_RS10745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IXO792_RS10750	COG0483	inositol monophosphate 1-phosphatase activity
IXO792_RS10765	COG5001	Diguanylate cyclase
IXO792_RS10765	COG3300	MHYT domain
IXO792_RS10770	COG1509	lysine 2,3-aminomutase activity
IXO792_RS10785	COG0402	S-adenosylhomocysteine deaminase activity
IXO792_RS10790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IXO792_RS10815	COG4677	pectinesterase activity
IXO792_RS10825	COG3039	Transposase
IXO792_RS10860	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IXO792_RS10890	COG2166	iron-sulfur cluster assembly
IXO792_RS10905	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IXO792_RS10910	COG0137	argininosuccinate synthase activity
IXO792_RS10920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO792_RS10925	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IXO792_RS10940	COG0165	Argininosuccinate lyase
IXO792_RS10960	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IXO792_RS10995	COG4988	ABC transporter
IXO792_RS11000	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IXO792_RS11075	COG3039	Transposase
IXO792_RS11095	COG3209	COG3209 Rhs family protein
IXO792_RS11120	COG3209	COG3209 Rhs family protein
IXO792_RS11130	COG3039	Transposase
IXO792_RS11155	COG0784	Response regulator, receiver
IXO792_RS11155	COG2198	Histidine kinase
IXO792_RS11155	COG0643	Histidine kinase
IXO792_RS11215	COG3190	flagellar
IXO792_RS11265	COG1677	Flagellar hook-basal body complex protein FliE
IXO792_RS11295	COG1028	Short-chain dehydrogenase reductase Sdr
IXO792_RS11305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IXO792_RS11325	COG2201	protein-glutamate methylesterase activity
IXO792_RS11360	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IXO792_RS11365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IXO792_RS11400	COG4787	bacterial-type flagellum-dependent cell motility
IXO792_RS11410	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IXO792_RS11415	COG1558	bacterial-type flagellum-dependent cell motility
IXO792_RS11425	COG0784	Response regulator, receiver
IXO792_RS11425	COG0835	chemotaxis
IXO792_RS11445	COG5002	protein histidine kinase activity
IXO792_RS11455	COG4585	Histidine kinase
IXO792_RS11460	COG5001	Diguanylate cyclase
IXO792_RS11485	COG0482	sulfurtransferase activity
IXO792_RS11500	COG0542	response to heat
IXO792_RS11535	COG0492	ferredoxin-NADP+ reductase activity
IXO792_RS11540	COG1674	ftsk spoiiie
IXO792_RS11560	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IXO792_RS11580	COG0038	chloride channel
IXO792_RS11585	COG0183	Belongs to the thiolase family
IXO792_RS11590	COG1024	Enoyl-CoA hydratase
IXO792_RS11590	COG1250	3-hydroxyacyl-CoA dehydrogenase
IXO792_RS11605	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IXO792_RS11615	COG1426	Protein conserved in bacteria
IXO792_RS11625	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO792_RS11635	COG0303	'Molybdopterin
IXO792_RS11695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IXO792_RS11735	COG0742	ribosomal rna small subunit methyltransferase
IXO792_RS11740	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IXO792_RS11750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IXO792_RS11755	COG0405	Gamma-glutamyltransferase
IXO792_RS11780	COG3039	Transposase
IXO792_RS11810	COG3039	Transposase
IXO792_RS11865	COG0343	queuine tRNA-ribosyltransferase activity
IXO792_RS11870	COG1862	Preprotein translocase
IXO792_RS11875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IXO792_RS11880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IXO792_RS11890	COG3039	Transposase
IXO792_RS11915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IXO792_RS11925	COG0704	Plays a role in the regulation of phosphate uptake
IXO792_RS11940	COG0573	inorganic phosphate transmembrane transporter activity
IXO792_RS11945	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IXO792_RS11985	COG3039	Transposase
IXO792_RS12010	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IXO792_RS12020	COG1024	Enoyl-CoA hydratase
IXO792_RS12035	COG0494	nUDIX hydrolase
IXO792_RS12080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IXO792_RS12080	COG0116	Belongs to the methyltransferase superfamily
IXO792_RS12105	COG0667	Aldo Keto reductase
IXO792_RS12115	COG2925	Exonuclease
IXO792_RS12140	COG0288	reversible hydration of carbon dioxide
IXO792_RS12170	COG0316	Belongs to the HesB IscA family
IXO792_RS12175	COG0360	Binds together with S18 to 16S ribosomal RNA
IXO792_RS12185	COG0359	binds to the 23S rRNA
IXO792_RS12195	COG3115	cell septum assembly
IXO792_RS12215	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IXO792_RS12230	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IXO792_RS12255	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IXO792_RS12265	COG2986	histidine ammonia-lyase
IXO792_RS12270	COG1228	amidohydrolase
IXO792_RS12310	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IXO792_RS12320	COG0077	Prephenate dehydratase
IXO792_RS12320	COG1605	Chorismate mutase
IXO792_RS12325	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IXO792_RS12350	COG3039	Transposase
IXO792_RS12360	COG4566	intracellular signal transduction
IXO792_RS12405	COG0860	N-Acetylmuramoyl-L-alanine amidase
IXO792_RS12410	COG1469	GTP cyclohydrolase I activity
IXO792_RS12420	COG0617	tRNA 3'-terminal CCA addition
IXO792_RS12430	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IXO792_RS12435	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IXO792_RS12465	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO792_RS12480	COG5001	Diguanylate cyclase
IXO792_RS12480	COG4251	negative regulation of phosphorylation
IXO792_RS12480	COG3706	GGDEF domain
IXO792_RS12480	COG2203	Gaf domain
IXO792_RS12565	COG0386	Belongs to the glutathione peroxidase family
IXO792_RS12635	COG3039	Transposase
IXO792_RS12650	COG2205	protein histidine kinase activity
IXO792_RS12650	COG5002	protein histidine kinase activity
IXO792_RS12650	COG0784	Response regulator, receiver
IXO792_RS12690	COG0800	Aldolase
IXO792_RS12695	COG0129	dihydroxy-acid dehydratase activity
IXO792_RS12700	COG0363	glucosamine-6-phosphate deaminase activity
IXO792_RS12710	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IXO792_RS12725	COG0354	folic acid binding
IXO792_RS12740	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IXO792_RS12755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IXO792_RS12770	COG4591	ABC-type transport system involved in lipoprotein release permease component
IXO792_RS12795	COG0811	peptide transport
IXO792_RS12810	COG1663	tetraacyldisaccharide 4'-kinase activity
IXO792_RS12820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IXO792_RS12830	COG0322	excinuclease ABC activity
IXO792_RS12865	COG3328	transposase activity
IXO792_RS12885	COG3039	Transposase
IXO792_RS12905	COG2201	protein-glutamate methylesterase activity
IXO792_RS12965	COG3039	Transposase
IXO792_RS13020	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IXO792_RS13020	COG0140	phosphoribosyl-ATP diphosphatase activity
IXO792_RS13030	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IXO792_RS13040	COG0131	Imidazoleglycerol-phosphate dehydratase
IXO792_RS13040	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IXO792_RS13055	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IXO792_RS13075	COG0124	histidyl-tRNA synthetase
IXO792_RS13090	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IXO792_RS13125	COG1012	belongs to the aldehyde dehydrogenase family
IXO792_RS13145	COG0167	dihydroorotate dehydrogenase activity
IXO792_RS13150	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IXO792_RS13155	COG0697	spore germination
IXO792_RS13180	COG0671	phosphoesterase, PA-phosphatase related
IXO792_RS13195	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IXO792_RS13210	COG2183	response to ionizing radiation
IXO792_RS13220	COG0723	plastoquinol--plastocyanin reductase activity
IXO792_RS13220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO792_RS13235	COG3243	poly(R)-hydroxyalkanoic acid synthase
IXO792_RS13245	COG1183	phosphatidylcholine synthase activity
IXO792_RS13250	COG1028	Short-chain dehydrogenase reductase Sdr
IXO792_RS13265	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IXO792_RS13275	COG0668	transmembrane transport
IXO792_RS13295	COG1914	H( )-stimulated, divalent metal cation uptake system
IXO792_RS13330	COG1028	Short-chain dehydrogenase reductase Sdr
IXO792_RS13345	COG0583	DNA-binding transcription factor activity
IXO792_RS13350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IXO792_RS13355	COG3002	Belongs to the UPF0753 family
IXO792_RS13450	COG0582	viral genome integration into host DNA
IXO792_RS13465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IXO792_RS13485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IXO792_RS13495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IXO792_RS13500	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IXO792_RS13510	COG0776	regulation of translation
IXO792_RS13515	COG0539	negative regulation of cytoplasmic translation
IXO792_RS13520	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IXO792_RS13535	COG2957	Belongs to the agmatine deiminase family
IXO792_RS13545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IXO792_RS13570	COG0395	ABC-type sugar transport system, permease component
IXO792_RS13575	COG1175	transmembrane transport
IXO792_RS13605	COG2350	Protein conserved in bacteria
IXO792_RS13610	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IXO792_RS13615	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IXO792_RS13620	COG1187	pseudouridine synthase activity
IXO792_RS13645	COG0436	Aminotransferase
IXO792_RS13710	COG0277	FAD linked oxidase domain protein
IXO792_RS13715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IXO792_RS13725	COG0531	amino acid
IXO792_RS13730	COG0531	amino acid
IXO792_RS13735	COG0235	Class ii aldolase
IXO792_RS13740	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IXO792_RS13820	COG0583	DNA-binding transcription factor activity
IXO792_RS13830	COG3039	Transposase
IXO792_RS13910	COG0174	glutamine synthetase
IXO792_RS13915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO792_RS13925	COG0477	Major facilitator Superfamily
IXO792_RS13935	COG0243	molybdopterin cofactor binding
IXO792_RS13945	COG2223	nitrite transmembrane transporter activity
IXO792_RS13950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IXO792_RS13955	COG1121	(ABC) transporter
IXO792_RS13965	COG2733	membrane
IXO792_RS13970	COG5002	protein histidine kinase activity
IXO792_RS13970	COG2205	protein histidine kinase activity
IXO792_RS13970	COG0784	Response regulator, receiver
IXO792_RS13980	COG3039	Transposase
IXO792_RS13985	COG2902	Dehydrogenase
IXO792_RS13995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO792_RS14000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO792_RS14025	COG1609	Transcriptional regulator
IXO792_RS14030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IXO792_RS14030	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO792_RS14035	COG1105	Belongs to the carbohydrate kinase PfkB family
IXO792_RS14040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IXO792_RS14040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IXO792_RS14055	COG3039	Transposase
IXO792_RS14080	COG3039	Transposase
IXO792_RS14120	COG3501	Rhs element vgr protein
IXO792_RS14120	COG3409	Peptidoglycan-binding domain 1 protein
IXO792_RS14140	COG3409	Peptidoglycan-binding domain 1 protein
IXO792_RS14140	COG3501	Rhs element vgr protein
IXO792_RS14175	COG4771	TonB-dependent receptor
IXO792_RS14185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IXO792_RS14205	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IXO792_RS14220	COG0835	chemotaxis
IXO792_RS14230	COG0745	RESPONSE REGULATOR receiver
IXO792_RS14260	COG0840	transmembrane signaling receptor activity
IXO792_RS14270	COG0840	transmembrane signaling receptor activity
IXO792_RS14280	COG0840	transmembrane signaling receptor activity
IXO792_RS14285	COG0840	transmembrane signaling receptor activity
IXO792_RS14290	COG0840	transmembrane signaling receptor activity
IXO792_RS14295	COG0840	transmembrane signaling receptor activity
IXO792_RS14310	COG0835	chemotaxis
IXO792_RS14330	COG3039	Transposase
IXO792_RS14385	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO792_RS14415	COG0318	PFAM AMP-dependent synthetase and ligase
IXO792_RS14420	COG1024	Enoyl-CoA hydratase
IXO792_RS14425	COG0784	Response regulator, receiver
IXO792_RS14425	COG2198	Histidine kinase
IXO792_RS14425	COG2205	protein histidine kinase activity
IXO792_RS14435	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IXO792_RS14485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IXO792_RS14495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO792_RS14500	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IXO792_RS14510	COG0505	Belongs to the CarA family
IXO792_RS14515	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IXO792_RS14525	COG2258	MOSC domain
IXO792_RS14530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IXO792_RS14575	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IXO792_RS14595	COG0477	Major facilitator Superfamily
IXO792_RS14605	COG1070	Carbohydrate kinase
IXO792_RS14615	COG1501	Belongs to the glycosyl hydrolase 31 family
IXO792_RS14630	COG0800	Aldolase
IXO792_RS14635	COG4948	Mandelate Racemase Muconate Lactonizing
IXO792_RS14645	COG3734	2-keto-3-deoxy-galactonokinase
IXO792_RS14650	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IXO792_RS14660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IXO792_RS14675	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IXO792_RS14680	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IXO792_RS14690	COG0351	phosphomethylpyrimidine kinase
IXO792_RS14715	COG0583	DNA-binding transcription factor activity
IXO792_RS14720	COG1741	Belongs to the pirin family
IXO792_RS14735	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IXO792_RS14740	COG0305	Participates in initiation and elongation during chromosome replication
IXO792_RS14760	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IXO792_RS14765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IXO792_RS14770	COG2137	regulation of response to DNA damage stimulus
IXO792_RS14775	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IXO792_RS14790	COG1546	Belongs to the CinA family
IXO792_RS14795	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IXO792_RS14805	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IXO792_RS14810	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IXO792_RS14820	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IXO792_RS14825	COG1534	Rna-binding protein
IXO792_RS14840	COG1238	metal cluster binding
IXO792_RS14845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IXO792_RS14850	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IXO792_RS14855	COG2840	Smr protein MutS2
IXO792_RS14865	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IXO792_RS14875	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IXO792_RS14880	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IXO792_RS14885	COG0148	phosphopyruvate hydratase activity
IXO792_RS14895	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IXO792_RS14900	COG0504	CTP synthase activity
IXO792_RS14930	COG0306	phosphate transporter
IXO792_RS14940	COG1253	flavin adenine dinucleotide binding
IXO792_RS14955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IXO792_RS14965	COG0477	Major facilitator Superfamily
IXO792_RS14975	COG1132	(ABC) transporter
IXO792_RS14980	COG1136	(ABC) transporter
IXO792_RS14995	COG0438	transferase activity, transferring glycosyl groups
IXO792_RS15005	COG2264	protein methyltransferase activity
IXO792_RS15035	COG2244	polysaccharide biosynthetic process
IXO792_RS15085	COG1595	DNA-templated transcription, initiation
IXO792_RS15100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IXO792_RS15120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IXO792_RS15150	COG2201	protein-glutamate methylesterase activity
IXO792_RS15235	COG1858	cytochrome C peroxidase
IXO792_RS15265	COG0515	serine threonine protein kinase
IXO792_RS15270	COG0631	protein serine/threonine phosphatase activity
IXO792_RS15385	COG3039	Transposase
IXO792_RS15455	COG2154	pterin-4-alpha-carbinolamine dehydratase
IXO792_RS15470	COG3064	Membrane
IXO792_RS15480	COG1530	ribonuclease E activity
IXO792_RS15495	COG1054	Belongs to the UPF0176 family
IXO792_RS15515	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IXO792_RS15555	COG3039	Transposase
IXO792_RS15565	COG3039	Transposase
IXO792_RS15600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IXO792_RS15600	COG1648	precorrin-2 dehydrogenase activity
IXO792_RS15625	COG0746	molybdenum cofactor guanylyltransferase activity
IXO792_RS15710	COG4206	TonB-dependent receptor
IXO792_RS15740	COG0531	amino acid
IXO792_RS15755	COG0006	proline dipeptidase activity
IXO792_RS15765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IXO792_RS15780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO792_RS15785	COG3938	Belongs to the proline racemase family
IXO792_RS15795	COG0552	protein localization to endoplasmic reticulum
IXO792_RS15805	COG1194	a g-specific adenine glycosylase
IXO792_RS15815	COG0784	Response regulator, receiver
IXO792_RS15815	COG4191	Histidine kinase
IXO792_RS15880	COG3039	Transposase
IXO792_RS15910	COG3040	lipid binding
IXO792_RS15950	COG0438	transferase activity, transferring glycosyl groups
IXO792_RS15960	COG0438	transferase activity, transferring glycosyl groups
IXO792_RS15965	COG0438	transferase activity, transferring glycosyl groups
IXO792_RS16020	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IXO792_RS16035	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IXO792_RS16075	COG0556	nucleotide-excision repair
IXO792_RS16080	COG4969	Belongs to the N-Me-Phe pilin family
IXO792_RS16120	COG1611	Belongs to the LOG family
IXO792_RS16135	COG2095	MarC family integral membrane protein
IXO792_RS16145	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IXO792_RS16180	COG1185	polyribonucleotide nucleotidyltransferase activity
IXO792_RS16185	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IXO792_RS16205	COG0195	Participates in both transcription termination and antitermination
IXO792_RS16210	COG0779	Required for maturation of 30S ribosomal subunits
IXO792_RS16220	COG1007	ATP synthesis coupled electron transport
IXO792_RS16250	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IXO792_RS16255	COG1034	ATP synthesis coupled electron transport
IXO792_RS16260	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IXO792_RS16265	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IXO792_RS16270	COG0649	NAD binding
IXO792_RS16275	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IXO792_RS16285	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IXO792_RS16300	COG0149	triose-phosphate isomerase activity
IXO792_RS16350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IXO792_RS16355	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IXO792_RS16360	COG0159	tryptophan synthase activity
IXO792_RS16380	COG0135	phosphoribosylanthranilate isomerase activity
IXO792_RS16385	COG0101	tRNA pseudouridine synthase activity
IXO792_RS16405	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IXO792_RS16410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IXO792_RS16415	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IXO792_RS16420	COG2890	protein-(glutamine-N5) methyltransferase activity
IXO792_RS16460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO792_RS16490	COG0717	Belongs to the dCTP deaminase family
IXO792_RS16495	COG0489	protein tyrosine kinase activity
IXO792_RS16535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO792_RS16540	COG2311	Membrane
IXO792_RS16545	COG1047	Peptidyl-prolyl cis-trans
IXO792_RS16550	COG0791	NLP P60 protein
IXO792_RS16555	COG0791	NLP P60 protein
IXO792_RS16580	COG1785	Belongs to the alkaline phosphatase family
IXO792_RS16585	COG0037	tRNA processing
IXO792_RS16590	COG1722	exodeoxyribonuclease VII activity
IXO792_RS16595	COG0142	geranyltranstransferase activity
IXO792_RS16620	COG0312	modulator of DNA gyrase
IXO792_RS16625	COG3028	Belongs to the UPF0307 family
IXO792_RS16630	COG0312	modulator of DNA gyrase
IXO792_RS16640	COG3164	Protein of unknown function
IXO792_RS16655	COG2968	Membrane
IXO792_RS16685	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IXO792_RS16710	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IXO792_RS16735	COG3118	belongs to the thioredoxin family
IXO792_RS16770	COG3039	Transposase
IXO792_RS16810	COG3039	Transposase
IXO792_RS16905	COG2022	thiamine diphosphate biosynthetic process
IXO792_RS16915	COG0471	metal ion transport
IXO792_RS16915	COG3273	potassium ion transport
IXO792_RS16945	COG1970	mechanosensitive ion channel activity
IXO792_RS16960	COG2272	Belongs to the type-B carboxylesterase lipase family
IXO792_RS16965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IXO792_RS16985	COG0308	aminopeptidase N
IXO792_RS16990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO792_RS17000	COG2895	sulfate adenylyltransferase (ATP) activity
IXO792_RS17000	COG0529	Catalyzes the synthesis of activated sulfate
IXO792_RS17005	COG0175	sulfate reduction
IXO792_RS17010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IXO792_RS17015	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IXO792_RS17020	COG0175	sulfate reduction
IXO792_RS17040	COG2205	protein histidine kinase activity
IXO792_RS17040	COG2198	Histidine kinase
IXO792_RS17040	COG0784	Response regulator, receiver
IXO792_RS17090	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IXO792_RS17095	COG3588	fructose-bisphosphate aldolase
IXO792_RS17100	COG0469	pyruvate kinase activity
IXO792_RS17140	COG0753	catalase activity
IXO792_RS17165	COG2207	Transcriptional regulator
IXO792_RS17165	COG1917	Cupin 2, conserved barrel domain protein
IXO792_RS17185	COG0823	Involved in the tonB-independent uptake of proteins
IXO792_RS17185	COG1506	peptidase
IXO792_RS17205	COG1297	OPT oligopeptide transporter protein
IXO792_RS17220	COG0587	DNA-directed DNA polymerase activity
IXO792_RS17300	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IXO792_RS17305	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
IXO792_RS17310	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
IXO792_RS17315	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IXO792_RS17335	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IXO792_RS17395	COG3039	Transposase
IXO792_RS17530	COG3179	chitinase
IXO792_RS17555	COG3039	Transposase
IXO792_RS17580	COG3179	chitinase
IXO792_RS17595	COG3328	transposase activity
IXO792_RS17675	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO792_RS17685	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO792_RS17785	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IXO792_RS17800	COG2197	response regulator
IXO792_RS17805	COG4585	Histidine kinase
IXO792_RS17820	COG2894	cell division
IXO792_RS17825	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IXO792_RS17835	COG0642	Histidine kinase
IXO792_RS17840	COG0745	RESPONSE REGULATOR receiver
IXO792_RS17845	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IXO792_RS17855	COG2194	sulfuric ester hydrolase activity
IXO792_RS17885	COG3551	Protein conserved in bacteria
IXO792_RS17945	COG0203	ribosomal protein L17
IXO792_RS17955	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IXO792_RS17960	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IXO792_RS17970	COG0201	protein transport
IXO792_RS17980	COG1841	ribosomal large subunit assembly
IXO792_RS17990	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IXO792_RS18010	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IXO792_RS18020	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IXO792_RS18025	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IXO792_RS18030	COG0255	Belongs to the universal ribosomal protein uL29 family
IXO792_RS18035	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IXO792_RS18045	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IXO792_RS18060	COG0089	rRNA binding
IXO792_RS18065	COG0088	Forms part of the polypeptide exit tunnel
IXO792_RS18070	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IXO792_RS18075	COG0051	transcription antitermination factor activity, RNA binding
IXO792_RS18095	COG0049	tRNA binding
IXO792_RS18100	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IXO792_RS18105	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IXO792_RS18110	COG0085	RNA polymerase activity
IXO792_RS18115	COG0222	ribosome binding
IXO792_RS18120	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IXO792_RS18130	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IXO792_RS18135	COG0250	Participates in transcription elongation, termination and antitermination
IXO792_RS18140	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IXO792_RS18170	COG0012	GTP binding
IXO792_RS18175	COG0193	aminoacyl-tRNA hydrolase activity
IXO792_RS18185	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IXO792_RS18200	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IXO792_RS18210	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IXO792_RS18215	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IXO792_RS18230	COG0521	Mo-molybdopterin cofactor biosynthetic process
IXO792_RS18250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IXO792_RS18255	COG1295	ribonuclease BN
IXO792_RS18285	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IXO792_RS18290	COG1404	Belongs to the peptidase S8 family
IXO792_RS18295	COG1404	Belongs to the peptidase S8 family
IXO792_RS18305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IXO792_RS18330	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IXO792_RS18355	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IXO792_RS18370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IXO792_RS18370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IXO792_RS18415	COG2890	protein-(glutamine-N5) methyltransferase activity
IXO792_RS18425	COG3634	alkyl hydroperoxide reductase activity
IXO792_RS18430	COG0583	DNA-binding transcription factor activity
IXO792_RS18440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IXO792_RS18465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IXO792_RS18500	COG0584	glycerophosphoryl diester phosphodiesterase
IXO792_RS18520	COG3039	Transposase
IXO792_RS18535	COG0625	glutathione transferase activity
IXO792_RS18540	COG0039	L-malate dehydrogenase activity
IXO792_RS18545	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IXO792_RS18550	COG1217	gtp-binding protein TYPA
IXO792_RS18570	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IXO792_RS18705	COG3781	membrane
IXO792_RS18715	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IXO792_RS18745	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IXO792_RS18765	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IXO792_RS18790	COG3710	Transcriptional regulator
IXO792_RS18795	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IXO792_RS18805	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IXO792_RS18835	COG2226	methyltransferase
IXO792_RS18840	COG0066	3-isopropylmalate dehydratase activity
IXO792_RS18845	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IXO792_RS18875	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IXO792_RS18880	COG1538	Outer membrane efflux protein
IXO792_RS18885	COG1519	Transferase
IXO792_RS18890	COG1560	Kdo2-lipid A biosynthetic process
IXO792_RS18950	COG0308	aminopeptidase N
IXO792_RS18955	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IXO792_RS18965	COG0330	HflC and HflK could
IXO792_RS18970	COG0330	HflC and HflK could
IXO792_RS18990	COG0678	peroxiredoxin activity
IXO792_RS19000	COG2826	transposase and inactivated derivatives, IS30 family
IXO792_RS19030	COG3039	Transposase
IXO792_RS19060	COG3829	transcription factor binding
IXO792_RS19095	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IXO792_RS19100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IXO792_RS19110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IXO792_RS19115	COG1028	Short-chain dehydrogenase reductase Sdr
IXO792_RS19140	COG1399	metal-binding, possibly nucleic acid-binding protein
IXO792_RS19155	COG3039	Transposase
IXO792_RS19190	COG1518	maintenance of DNA repeat elements
IXO792_RS19195	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IXO792_RS19240	COG2188	Transcriptional regulator
IXO792_RS19255	COG1450	Type ii and iii secretion system protein
IXO792_RS19270	COG3166	PFAM Fimbrial assembly family protein
IXO792_RS19275	COG3156	type II secretion system protein K
IXO792_RS19280	COG4795	General secretion pathway protein
IXO792_RS19285	COG2165	general secretion pathway protein
IXO792_RS19290	COG4970	Tfp pilus assembly protein FimT
IXO792_RS19295	COG2165	general secretion pathway protein
IXO792_RS19300	COG1459	type II secretion system
IXO792_RS19310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IXO792_RS19320	COG5295	Hep Hag repeat protein
IXO792_RS19325	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IXO792_RS19325	COG0047	phosphoribosylformylglycinamidine synthase activity
IXO792_RS19330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IXO792_RS19335	COG4974	Belongs to the 'phage' integrase family
IXO792_RS19350	COG0795	lipopolysaccharide-transporting ATPase activity
IXO792_RS19360	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IXO792_RS19375	COG0525	valine-tRNA ligase activity
IXO792_RS19410	COG3039	Transposase
IXO792_RS19445	COG3039	Transposase
IXO792_RS19475	COG1183	phosphatidylcholine synthase activity
IXO792_RS19485	COG0442	prolyl-tRNA aminoacylation
IXO792_RS19500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IXO792_RS19505	COG1127	ABC transporter
IXO792_RS19510	COG3218	ABC-type transport auxiliary lipoprotein component
IXO792_RS19510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IXO792_RS19545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IXO792_RS19550	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IXO792_RS19550	COG0662	Cupin 2, conserved barrel domain protein
IXO792_RS19575	COG2086	electron transfer activity
IXO792_RS19600	COG3328	transposase activity
IXO792_RS19640	COG0626	cystathionine gamma-synthase activity
IXO792_RS19670	COG0625	glutathione transferase activity
IXO792_RS19680	COG0513	Belongs to the DEAD box helicase family
IXO792_RS19685	COG0720	synthase
IXO792_RS19695	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IXO792_RS19700	COG1956	GAF domain-containing protein
IXO792_RS19735	COG0339	signal peptide processing
IXO792_RS19785	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IXO792_RS19790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO792_RS19840	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IXO792_RS19845	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IXO792_RS19850	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IXO792_RS19855	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IXO792_RS19865	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IXO792_RS19875	COG0356	it plays a direct role in the translocation of protons across the membrane
IXO792_RS19895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IXO792_RS19905	COG0508	dehydrogenase complex catalyzes the overall conversion of
IXO792_RS19935	COG2011	ABC-type metal ion transport system permease component
IXO792_RS19945	COG0697	spore germination
IXO792_RS19980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IXO792_RS19985	COG1187	pseudouridine synthase activity
IXO792_RS19990	COG2813	Specifically methylates the guanine in position
IXO792_RS20020	COG2202	Pas domain
IXO792_RS20020	COG2205	protein histidine kinase activity
IXO792_RS20045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO792_RS20095	COG0745	RESPONSE REGULATOR receiver
IXO792_RS20110	COG1404	Belongs to the peptidase S8 family
IXO792_RS20125	COG0842	Transport permease protein
IXO792_RS20130	COG1131	(ABC) transporter
IXO792_RS20135	COG0025	NhaP-type Na H and K H
IXO792_RS20145	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IXO792_RS20155	COG1573	uracil-dna glycosylase
IXO792_RS20165	COG3384	dioxygenase
IXO792_RS20180	COG0667	Aldo Keto reductase
IXO792_RS20190	COG3590	peptidase
IXO792_RS20210	COG0531	amino acid
IXO792_RS20235	COG2972	Histidine kinase
IXO792_RS20285	COG1271	oxidase subunit
IXO792_RS20445	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IXO792_RS20455	COG1560	Kdo2-lipid A biosynthetic process
IXO792_RS20505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IXO792_RS20505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IXO792_RS20510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IXO792_RS20515	COG0242	peptide deformylase activity
IXO792_RS20520	COG1652	LysM domain
IXO792_RS20525	COG0758	DNA mediated transformation
IXO792_RS20530	COG2922	Belongs to the Smg family
IXO792_RS20545	COG1754	DNA topoisomerase type I activity
IXO792_RS20545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IXO792_RS20550	COG0009	L-threonylcarbamoyladenylate synthase
IXO792_RS20565	COG1028	Short-chain dehydrogenase reductase Sdr
IXO792_RS20575	COG0616	signal peptide processing
IXO792_RS20580	COG0534	Mate efflux family protein
IXO792_RS20600	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IXO792_RS20635	COG1324	tolerance protein
IXO792_RS20645	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IXO792_RS20650	COG0511	ligase activity, forming carbon-carbon bonds
IXO792_RS20660	COG0439	Biotin carboxylase
IXO792_RS20700	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IXO792_RS20785	COG3039	Transposase
IXO792_RS20855	COG3210	domain, Protein
IXO792_RS20860	COG2831	hemolysin activation secretion protein
IXO792_RS20900	COG0138	bifunctional purine biosynthesis protein purh
IXO792_RS20910	COG0151	Belongs to the GarS family
IXO792_RS20915	COG0577	efflux transmembrane transporter activity
IXO792_RS20915	COG1136	(ABC) transporter
IXO792_RS20935	COG1289	transmembrane transporter activity
IXO792_RS20950	COG2814	Major facilitator Superfamily
IXO792_RS20965	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IXO792_RS21000	COG0745	RESPONSE REGULATOR receiver
IXO792_RS21045	COG0739	heme binding
IXO792_RS21060	COG2211	Major facilitator Superfamily
IXO792_RS21065	COG0708	Exodeoxyribonuclease III
IXO792_RS21080	COG1192	Involved in chromosome partitioning
IXO792_RS21085	COG1475	DNA binding
IXO792_RS21100	COG0463	Glycosyl transferase, family 2
IXO792_RS21125	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IXO792_RS21135	COG0018	arginyl-trna synthetase
IXO792_RS21150	COG4221	oxidoreductase activity
IXO792_RS21175	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IXO792_RS21180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO792_RS21195	COG3485	protocatechuate 3,4-dioxygenase
IXO792_RS21200	COG3485	protocatechuate 3,4-dioxygenase
IXO792_RS21235	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IXO792_RS21240	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IXO792_RS21250	COG1042	CoA-binding domain protein
IXO792_RS21250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IXO792_RS21250	COG0045	succinate-CoA ligase (ADP-forming) activity
IXO792_RS21265	COG2239	Acts as a magnesium transporter
IXO792_RS21280	COG3039	Transposase
IXO792_RS21290	COG3328	transposase activity
IXO792_RS21300	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IXO792_RS21300	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IXO792_RS21310	COG1473	amidohydrolase
IXO792_RS21315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO792_RS21320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO792_RS21330	COG5383	Protein conserved in bacteria
IXO792_RS21355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IXO792_RS21360	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IXO792_RS21375	COG0028	Belongs to the TPP enzyme family
IXO792_RS21380	COG4191	Histidine kinase
IXO792_RS21405	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IXO792_RS21420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IXO792_RS21425	COG3177	Filamentation induced by cAMP protein fic
IXO792_RS21440	COG0596	Alpha beta hydrolase
IXO792_RS21445	COG0727	PFAM Uncharacterised protein family (UPF0153)
IXO792_RS21450	COG0318	PFAM AMP-dependent synthetase and ligase
IXO792_RS21455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IXO792_RS21505	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IXO792_RS21515	COG0129	dihydroxy-acid dehydratase activity
IXO792_RS21535	COG3039	Transposase
IXO792_RS21545	COG0408	coproporphyrinogen oxidase activity
IXO792_RS21585	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IXO792_RS21655	COG2353	YceI-like domain
IXO792_RS21685	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IXO792_RS21700	COG3386	PFAM SMP-30 Gluconolaconase
IXO792_RS21730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IXO792_RS21750	COG0459	protein refolding
IXO792_RS21775	COG1252	NADH dehydrogenase
IXO792_RS21785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IXO792_RS21790	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IXO792_RS21795	COG2201	protein-glutamate methylesterase activity
IXO792_RS21800	COG2177	Part of the ABC transporter FtsEX involved in
IXO792_RS21805	COG2884	Cell division ATP-binding protein ftsE
IXO792_RS21815	COG3118	belongs to the thioredoxin family
IXO792_RS21820	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IXO792_RS21835	COG0729	surface antigen
IXO792_RS21840	COG2911	Protein conserved in bacteria
IXO792_RS21890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IXO792_RS21945	COG1733	regulation of RNA biosynthetic process
IXO792_RS21950	COG0702	epimerase
IXO792_RS21980	COG0583	DNA-binding transcription factor activity
IXO792_RS21985	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IXO792_RS22005	COG0745	RESPONSE REGULATOR receiver
IXO792_RS22035	COG1902	pentaerythritol trinitrate reductase activity
IXO792_RS22040	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IXO792_RS22050	COG2814	Major facilitator Superfamily
IXO792_RS22055	COG0583	DNA-binding transcription factor activity
IXO792_RS22070	COG0084	hydrolase, TatD family'
IXO792_RS22115	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IXO792_RS22140	COG2351	hydroxyisourate hydrolase activity
IXO792_RS22200	COG4770	biotin carboxylase activity
IXO792_RS22205	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IXO792_RS22210	COG1960	acyl-CoA dehydrogenase activity
IXO792_RS22265	COG0523	cobalamin synthesis protein
IXO792_RS22285	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IXO792_RS22305	COG4771	TonB-dependent receptor
IXO792_RS22310	COG0457	Tetratricopeptide repeat
IXO792_RS22320	COG0752	glycyl-tRNA synthetase alpha subunit
IXO792_RS22325	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IXO792_RS22340	COG0519	Catalyzes the synthesis of GMP from XMP
IXO792_RS22340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IXO792_RS22350	COG0805	protein transport
IXO792_RS22360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IXO792_RS22370	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IXO792_RS22395	COG2974	May be involved in recombination
IXO792_RS22400	COG0037	tRNA processing
IXO792_RS22420	COG3661	Belongs to the glycosyl hydrolase 67 family
IXO792_RS22430	COG4948	Mandelate Racemase Muconate Lactonizing
IXO792_RS22440	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO792_RS22445	COG0246	Mannitol dehydrogenase
IXO792_RS22470	COG3693	PFAM glycoside hydrolase, family 10
IXO792_RS22495	COG2211	Major facilitator Superfamily
IXO792_RS22580	COG1846	Transcriptional regulator
IXO792_RS22585	COG1764	response to oxidative stress
IXO792_RS22665	COG3549	Plasmid maintenance system killer
IXO792_RS22675	COG1074	ATP-dependent DNA helicase activity
IXO792_RS22680	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IXO792_RS22695	COG1196	nuclear chromosome segregation
IXO792_RS22730	COG2032	superoxide dismutase activity
IXO792_RS22735	COG2032	superoxide dismutase activity
IXO792_RS22740	COG2204	response regulator
IXO792_RS22745	COG3852	Histidine kinase
IXO792_RS22750	COG0004	ammonium transporteR
IXO792_RS22755	COG0347	Belongs to the P(II) protein family
IXO792_RS22760	COG0174	glutamine synthetase
IXO792_RS22765	COG1968	undecaprenyl-diphosphatase activity
IXO792_RS22805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO792_RS22815	COG2062	phosphohistidine phosphatase, SixA
IXO792_RS22820	COG0489	protein tyrosine kinase activity
IXO792_RS22840	COG1396	sequence-specific DNA binding
IXO792_RS22845	COG3550	peptidyl-serine autophosphorylation
IXO792_RS22850	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IXO792_RS22855	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO792_RS22870	COG1125	glycine betaine transport
IXO792_RS22870	COG0517	IMP dehydrogenase activity
IXO792_RS22885	COG1119	ATPase activity
IXO792_RS22895	COG1752	Esterase of the alpha-beta hydrolase superfamily
IXO792_RS22910	COG3039	Transposase
IXO792_RS22925	COG0656	L-ascorbic acid biosynthetic process
IXO792_RS22930	COG2130	NADP-dependent
IXO792_RS22935	COG0667	Aldo Keto reductase
IXO792_RS22945	COG1187	pseudouridine synthase activity
IXO792_RS22960	COG1643	Atp-dependent helicase
IXO792_RS22965	COG4807	Protein conserved in bacteria
IXO792_RS22970	COG4948	Mandelate Racemase Muconate Lactonizing
IXO792_RS22975	COG0179	Fumarylacetoacetate (FAA) hydrolase
IXO792_RS22980	COG1028	Short-chain dehydrogenase reductase Sdr
IXO792_RS23040	COG3162	membrane
IXO792_RS23045	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IXO792_RS23065	COG0708	Exodeoxyribonuclease III
IXO792_RS23080	COG2091	lysine biosynthetic process via aminoadipic acid
IXO792_RS23090	COG3540	Alkaline phosphatase
IXO792_RS23095	COG0357	Ribosomal RNA small subunit methyltransferase G
IXO792_RS23115	COG2159	amidohydrolase
IXO792_RS23125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IXO792_RS23130	COG0583	DNA-binding transcription factor activity
IXO792_RS23135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO792_RS23150	COG0210	DNA helicase
IXO792_RS23175	COG0531	amino acid
IXO792_RS23185	COG1322	Protein conserved in bacteria
IXO792_RS23195	COG0386	Belongs to the glutathione peroxidase family
IXO792_RS23255	COG0793	Belongs to the peptidase S41A family
IXO792_RS23260	COG4942	peptidase
IXO792_RS23270	COG2234	aminopeptidase activity
IXO792_RS23315	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IXO792_RS23320	COG0302	gtp cyclohydrolase
IXO792_RS23345	COG0477	Major facilitator Superfamily
IXO792_RS23460	COG3039	Transposase
IXO792_RS23470	COG1929	Belongs to the glycerate kinase type-1 family
IXO792_RS23475	COG2271	Major facilitator Superfamily
IXO792_RS23490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IXO792_RS23495	COG0861	Integral membrane protein TerC family
IXO792_RS23510	COG0584	glycerophosphoryl diester phosphodiesterase
IXO792_RS23520	COG0671	phosphoesterase, PA-phosphatase related
IXO792_RS23530	COG0726	polysaccharide deacetylase
IXO792_RS23535	COG0706	membrane insertase activity