locus-tag	class	description
G6N84_RS00030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6N84_RS00035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6N84_RS00055	COG2201	protein-glutamate methylesterase activity
G6N84_RS00100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6N84_RS00120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G6N84_RS00135	COG1595	DNA-templated transcription, initiation
G6N84_RS00185	COG2244	polysaccharide biosynthetic process
G6N84_RS00215	COG2264	protein methyltransferase activity
G6N84_RS00225	COG0438	transferase activity, transferring glycosyl groups
G6N84_RS00240	COG1136	(ABC) transporter
G6N84_RS00245	COG1132	(ABC) transporter
G6N84_RS00255	COG0477	Major facilitator Superfamily
G6N84_RS00265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N84_RS00280	COG1253	flavin adenine dinucleotide binding
G6N84_RS00290	COG0306	phosphate transporter
G6N84_RS00320	COG0504	CTP synthase activity
G6N84_RS00325	COG2877	3-deoxy-8-phosphooctulonate synthase activity
G6N84_RS00335	COG0148	phosphopyruvate hydratase activity
G6N84_RS00340	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G6N84_RS00345	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G6N84_RS00355	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G6N84_RS00365	COG2840	Smr protein MutS2
G6N84_RS00370	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G6N84_RS00375	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G6N84_RS00380	COG1238	metal cluster binding
G6N84_RS00395	COG1534	Rna-binding protein
G6N84_RS00400	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G6N84_RS00410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G6N84_RS00425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G6N84_RS00430	COG1546	Belongs to the CinA family
G6N84_RS00445	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G6N84_RS00450	COG2137	regulation of response to DNA damage stimulus
G6N84_RS00455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G6N84_RS00460	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
G6N84_RS00480	COG0305	Participates in initiation and elongation during chromosome replication
G6N84_RS00485	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G6N84_RS00505	COG1741	Belongs to the pirin family
G6N84_RS00510	COG0583	DNA-binding transcription factor activity
G6N84_RS00540	COG0351	phosphomethylpyrimidine kinase
G6N84_RS00550	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G6N84_RS00555	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G6N84_RS00570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N84_RS00580	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G6N84_RS00585	COG3734	2-keto-3-deoxy-galactonokinase
G6N84_RS00595	COG4948	Mandelate Racemase Muconate Lactonizing
G6N84_RS00600	COG0800	Aldolase
G6N84_RS00615	COG1501	Belongs to the glycosyl hydrolase 31 family
G6N84_RS00625	COG1070	Carbohydrate kinase
G6N84_RS00635	COG0477	Major facilitator Superfamily
G6N84_RS00655	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G6N84_RS00705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6N84_RS00710	COG2258	MOSC domain
G6N84_RS00720	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N84_RS00725	COG0505	Belongs to the CarA family
G6N84_RS00735	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G6N84_RS00740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G6N84_RS00750	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G6N84_RS00820	COG0784	Response regulator, receiver
G6N84_RS00820	COG2205	protein histidine kinase activity
G6N84_RS00820	COG2198	Histidine kinase
G6N84_RS00825	COG1024	Enoyl-CoA hydratase
G6N84_RS00830	COG0318	PFAM AMP-dependent synthetase and ligase
G6N84_RS00860	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N84_RS00895	COG0840	transmembrane signaling receptor activity
G6N84_RS00915	COG0835	chemotaxis
G6N84_RS00930	COG0840	transmembrane signaling receptor activity
G6N84_RS00935	COG0840	transmembrane signaling receptor activity
G6N84_RS00940	COG0840	transmembrane signaling receptor activity
G6N84_RS00945	COG0840	transmembrane signaling receptor activity
G6N84_RS00955	COG0840	transmembrane signaling receptor activity
G6N84_RS00965	COG0840	transmembrane signaling receptor activity
G6N84_RS00975	COG0840	transmembrane signaling receptor activity
G6N84_RS00995	COG0745	RESPONSE REGULATOR receiver
G6N84_RS01005	COG0835	chemotaxis
G6N84_RS01015	COG1360	Flagellar Motor Protein
G6N84_RS01020	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G6N84_RS01040	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G6N84_RS01050	COG4771	TonB-dependent receptor
G6N84_RS01065	COG3039	Transposase
G6N84_RS01080	COG3039	Transposase
G6N84_RS01130	COG3501	Rhs element vgr protein
G6N84_RS01135	COG3039	Transposase
G6N84_RS01150	COG3501	Rhs element vgr protein
G6N84_RS01180	COG3039	Transposase
G6N84_RS01195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G6N84_RS01195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G6N84_RS01200	COG1105	Belongs to the carbohydrate kinase PfkB family
G6N84_RS01205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6N84_RS01205	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6N84_RS01210	COG1609	Transcriptional regulator
G6N84_RS01230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6N84_RS01235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6N84_RS01245	COG2902	Dehydrogenase
G6N84_RS01250	COG3039	Transposase
G6N84_RS01265	COG0477	Major facilitator Superfamily
G6N84_RS01280	COG5002	protein histidine kinase activity
G6N84_RS01280	COG2205	protein histidine kinase activity
G6N84_RS01280	COG0784	Response regulator, receiver
G6N84_RS01285	COG2733	membrane
G6N84_RS01300	COG3039	Transposase
G6N84_RS01325	COG2223	nitrite transmembrane transporter activity
G6N84_RS01335	COG0243	molybdopterin cofactor binding
G6N84_RS01345	COG0477	Major facilitator Superfamily
G6N84_RS01355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6N84_RS01360	COG0174	glutamine synthetase
G6N84_RS01400	COG3842	ATPase activity
G6N84_RS01410	COG1177	transmembrane transport
G6N84_RS01420	COG1012	belongs to the aldehyde dehydrogenase family
G6N84_RS01435	COG4535	Mg2 and Co2 transporter CorC
G6N84_RS01455	COG1702	phosphate starvation-inducible protein PhoH
G6N84_RS01480	COG0741	lytic transglycosylase activity
G6N84_RS01485	COG0723	plastoquinol--plastocyanin reductase activity
G6N84_RS01490	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G6N84_RS01495	COG2857	Cytochrome c1
G6N84_RS01500	COG0625	glutathione transferase activity
G6N84_RS01505	COG2969	positive regulation of protein catabolic process
G6N84_RS01545	COG3328	transposase activity
G6N84_RS01620	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N84_RS01640	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G6N84_RS01645	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G6N84_RS01645	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G6N84_RS01650	COG0802	atpase or kinase
G6N84_RS01655	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N84_RS01660	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G6N84_RS01680	COG1028	Short-chain dehydrogenase reductase Sdr
G6N84_RS01700	COG2081	HI0933 family
G6N84_RS01705	COG4681	YaeQ
G6N84_RS01710	COG1671	Belongs to the UPF0178 family
G6N84_RS01720	COG0625	glutathione transferase activity
G6N84_RS01740	COG0513	Belongs to the DEAD box helicase family
G6N84_RS01765	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G6N84_RS01770	COG0483	inositol monophosphate 1-phosphatase activity
G6N84_RS01785	COG5001	Diguanylate cyclase
G6N84_RS01785	COG3300	MHYT domain
G6N84_RS01790	COG1509	lysine 2,3-aminomutase activity
G6N84_RS01805	COG0402	S-adenosylhomocysteine deaminase activity
G6N84_RS01810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G6N84_RS01825	COG4677	pectinesterase activity
G6N84_RS01835	COG3039	Transposase
G6N84_RS01870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G6N84_RS01895	COG2166	iron-sulfur cluster assembly
G6N84_RS01910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G6N84_RS01915	COG0137	argininosuccinate synthase activity
G6N84_RS01925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6N84_RS01930	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G6N84_RS01945	COG0165	Argininosuccinate lyase
G6N84_RS02000	COG3039	Transposase
G6N84_RS02015	COG4988	ABC transporter
G6N84_RS02020	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G6N84_RS02030	COG3039	Transposase
G6N84_RS02130	COG0784	Response regulator, receiver
G6N84_RS02130	COG2198	Histidine kinase
G6N84_RS02130	COG0643	Histidine kinase
G6N84_RS02175	COG5001	Diguanylate cyclase
G6N84_RS02175	COG3300	MHYT domain
G6N84_RS02180	COG3300	MHYT domain
G6N84_RS02180	COG5001	Diguanylate cyclase
G6N84_RS02185	COG1684	flagellar biosynthetic protein fliR
G6N84_RS02200	COG3190	flagellar
G6N84_RS02250	COG1677	Flagellar hook-basal body complex protein FliE
G6N84_RS02280	COG1028	Short-chain dehydrogenase reductase Sdr
G6N84_RS02290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6N84_RS02310	COG2201	protein-glutamate methylesterase activity
G6N84_RS02340	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G6N84_RS02345	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G6N84_RS02385	COG4787	bacterial-type flagellum-dependent cell motility
G6N84_RS02395	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
G6N84_RS02400	COG1558	bacterial-type flagellum-dependent cell motility
G6N84_RS02410	COG0784	Response regulator, receiver
G6N84_RS02410	COG0835	chemotaxis
G6N84_RS02430	COG5002	protein histidine kinase activity
G6N84_RS02440	COG4585	Histidine kinase
G6N84_RS02445	COG5001	Diguanylate cyclase
G6N84_RS02470	COG0482	sulfurtransferase activity
G6N84_RS02485	COG0542	response to heat
G6N84_RS02510	COG0492	ferredoxin-NADP+ reductase activity
G6N84_RS02515	COG1674	ftsk spoiiie
G6N84_RS02535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G6N84_RS02555	COG0038	chloride channel
G6N84_RS02560	COG0183	Belongs to the thiolase family
G6N84_RS02565	COG1024	Enoyl-CoA hydratase
G6N84_RS02565	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N84_RS02580	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G6N84_RS02590	COG1426	Protein conserved in bacteria
G6N84_RS02600	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6N84_RS02610	COG0303	'Molybdopterin
G6N84_RS02670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G6N84_RS02690	COG0742	ribosomal rna small subunit methyltransferase
G6N84_RS02695	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G6N84_RS02705	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G6N84_RS02710	COG0405	Gamma-glutamyltransferase
G6N84_RS02760	COG3039	Transposase
G6N84_RS02800	COG0343	queuine tRNA-ribosyltransferase activity
G6N84_RS02805	COG1862	Preprotein translocase
G6N84_RS02810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G6N84_RS02815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G6N84_RS02845	COG3328	transposase activity
G6N84_RS02860	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G6N84_RS02870	COG0704	Plays a role in the regulation of phosphate uptake
G6N84_RS02885	COG0573	inorganic phosphate transmembrane transporter activity
G6N84_RS02890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G6N84_RS02925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G6N84_RS02935	COG1024	Enoyl-CoA hydratase
G6N84_RS02950	COG0494	nUDIX hydrolase
G6N84_RS03025	COG0667	Aldo Keto reductase
G6N84_RS03035	COG2925	Exonuclease
G6N84_RS03070	COG0288	reversible hydration of carbon dioxide
G6N84_RS03100	COG0316	Belongs to the HesB IscA family
G6N84_RS03105	COG0360	Binds together with S18 to 16S ribosomal RNA
G6N84_RS03115	COG0359	binds to the 23S rRNA
G6N84_RS03125	COG3115	cell septum assembly
G6N84_RS03145	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
G6N84_RS03160	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
G6N84_RS03185	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G6N84_RS03195	COG2986	histidine ammonia-lyase
G6N84_RS03200	COG1228	amidohydrolase
G6N84_RS03240	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G6N84_RS03250	COG0077	Prephenate dehydratase
G6N84_RS03250	COG1605	Chorismate mutase
G6N84_RS03255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G6N84_RS03280	COG3039	Transposase
G6N84_RS03295	COG4566	intracellular signal transduction
G6N84_RS03340	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N84_RS03345	COG1469	GTP cyclohydrolase I activity
G6N84_RS03355	COG0617	tRNA 3'-terminal CCA addition
G6N84_RS03365	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G6N84_RS03370	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G6N84_RS03400	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N84_RS03420	COG5001	Diguanylate cyclase
G6N84_RS03420	COG4251	negative regulation of phosphorylation
G6N84_RS03420	COG2203	Gaf domain
G6N84_RS03420	COG3706	GGDEF domain
G6N84_RS03505	COG0386	Belongs to the glutathione peroxidase family
G6N84_RS03560	COG3706	GGDEF domain
G6N84_RS03585	COG0784	Response regulator, receiver
G6N84_RS03585	COG2205	protein histidine kinase activity
G6N84_RS03585	COG5002	protein histidine kinase activity
G6N84_RS03615	COG0800	Aldolase
G6N84_RS03620	COG0129	dihydroxy-acid dehydratase activity
G6N84_RS03625	COG0363	glucosamine-6-phosphate deaminase activity
G6N84_RS03635	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G6N84_RS03650	COG0354	folic acid binding
G6N84_RS03665	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G6N84_RS03680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G6N84_RS03695	COG4591	ABC-type transport system involved in lipoprotein release permease component
G6N84_RS03720	COG0811	peptide transport
G6N84_RS03735	COG1663	tetraacyldisaccharide 4'-kinase activity
G6N84_RS03745	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6N84_RS03755	COG0322	excinuclease ABC activity
G6N84_RS03785	COG3039	Transposase
G6N84_RS03795	COG3328	transposase activity
G6N84_RS03815	COG3039	Transposase
G6N84_RS03835	COG2801	Transposase and inactivated derivatives
G6N84_RS03845	COG2201	protein-glutamate methylesterase activity
G6N84_RS03985	COG0653	protein targeting
G6N84_RS04020	COG0140	phosphoribosyl-ATP diphosphatase activity
G6N84_RS04020	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G6N84_RS04030	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G6N84_RS04040	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G6N84_RS04040	COG0131	Imidazoleglycerol-phosphate dehydratase
G6N84_RS04055	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G6N84_RS04075	COG0124	histidyl-tRNA synthetase
G6N84_RS04090	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G6N84_RS04125	COG1012	belongs to the aldehyde dehydrogenase family
G6N84_RS04155	COG0697	spore germination
G6N84_RS04160	COG1794	racemase activity, acting on amino acids and derivatives
G6N84_RS04185	COG0671	phosphoesterase, PA-phosphatase related
G6N84_RS04200	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
G6N84_RS04215	COG2183	response to ionizing radiation
G6N84_RS04225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6N84_RS04225	COG0723	plastoquinol--plastocyanin reductase activity
G6N84_RS04240	COG3243	poly(R)-hydroxyalkanoic acid synthase
G6N84_RS04250	COG1183	phosphatidylcholine synthase activity
G6N84_RS04255	COG1028	Short-chain dehydrogenase reductase Sdr
G6N84_RS04305	COG0668	transmembrane transport
G6N84_RS04325	COG1914	H( )-stimulated, divalent metal cation uptake system
G6N84_RS04375	COG0583	DNA-binding transcription factor activity
G6N84_RS04380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G6N84_RS04400	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G6N84_RS04420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G6N84_RS04430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G6N84_RS04435	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G6N84_RS04445	COG0776	regulation of translation
G6N84_RS04450	COG0539	negative regulation of cytoplasmic translation
G6N84_RS04455	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G6N84_RS04470	COG2957	Belongs to the agmatine deiminase family
G6N84_RS04480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6N84_RS04505	COG0395	ABC-type sugar transport system, permease component
G6N84_RS04510	COG1175	transmembrane transport
G6N84_RS04550	COG2350	Protein conserved in bacteria
G6N84_RS04555	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G6N84_RS04560	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G6N84_RS04565	COG1187	pseudouridine synthase activity
G6N84_RS04590	COG0436	Aminotransferase
G6N84_RS04655	COG0277	FAD linked oxidase domain protein
G6N84_RS04660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6N84_RS04670	COG0531	amino acid
G6N84_RS04675	COG0531	amino acid
G6N84_RS04685	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
G6N84_RS04715	COG2201	protein-glutamate methylesterase activity
G6N84_RS04760	COG0583	DNA-binding transcription factor activity
G6N84_RS04770	COG3039	Transposase
G6N84_RS04865	COG3039	Transposase
G6N84_RS04870	COG3039	Transposase
G6N84_RS04890	COG1278	Cold shock
G6N84_RS04900	COG3328	transposase activity
G6N84_RS04920	COG3039	Transposase
G6N84_RS04930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6N84_RS04950	COG0557	exoribonuclease II activity
G6N84_RS04975	COG1960	acyl-CoA dehydrogenase activity
G6N84_RS04980	COG2226	methyltransferase
G6N84_RS04985	COG0646	methionine synthase
G6N84_RS04985	COG1410	methionine synthase
G6N84_RS04990	COG0646	methionine synthase
G6N84_RS04990	COG1410	methionine synthase
G6N84_RS05000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N84_RS05025	COG2900	Belongs to the SlyX family
G6N84_RS05040	COG0386	Belongs to the glutathione peroxidase family
G6N84_RS05050	COG1725	Transcriptional regulator
G6N84_RS05055	COG1131	(ABC) transporter
G6N84_RS05130	COG2850	peptidyl-arginine hydroxylation
G6N84_RS05165	COG1132	(ABC) transporter
G6N84_RS05180	COG0583	DNA-binding transcription factor activity
G6N84_RS05195	COG0287	Prephenate dehydrogenase
G6N84_RS05195	COG1605	Chorismate mutase
G6N84_RS05200	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
G6N84_RS05205	COG0484	heat shock protein binding
G6N84_RS05215	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G6N84_RS05225	COG0497	DNA recombination
G6N84_RS05235	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6N84_RS05240	COG2914	Belongs to the UPF0125 (RnfH) family
G6N84_RS05250	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G6N84_RS05265	COG1960	acyl-CoA dehydrogenase activity
G6N84_RS05275	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G6N84_RS05320	COG2814	Major facilitator Superfamily
G6N84_RS05325	COG1566	PFAM secretion protein HlyD family protein
G6N84_RS05340	COG2207	Transcriptional regulator
G6N84_RS05360	COG4774	siderophore transport
G6N84_RS05370	COG0367	asparagine synthase
G6N84_RS05385	COG1393	Belongs to the ArsC family
G6N84_RS05445	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G6N84_RS05460	COG0233	cytoplasmic translational termination
G6N84_RS05470	COG0575	Belongs to the CDS family
G6N84_RS05480	COG0750	zinc metalloprotease
G6N84_RS05495	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G6N84_RS05500	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G6N84_RS05520	COG0825	malonyl-CoA metabolic process
G6N84_RS05530	COG4771	TonB-dependent receptor
G6N84_RS05535	COG1131	(ABC) transporter
G6N84_RS05605	COG0529	Catalyzes the synthesis of activated sulfate
G6N84_RS05605	COG2895	sulfate adenylyltransferase (ATP) activity
G6N84_RS05640	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G6N84_RS05655	COG2040	homocysteine
G6N84_RS05660	COG0833	amino acid
G6N84_RS05680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6N84_RS05680	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6N84_RS05690	COG2878	Part of a membrane complex involved in electron transport
G6N84_RS05705	COG1595	DNA-templated transcription, initiation
G6N84_RS05730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N84_RS05745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N84_RS05750	COG0251	oxidation-reduction process
G6N84_RS05760	COG0392	lysyltransferase activity
G6N84_RS05760	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G6N84_RS05795	COG2814	Major facilitator Superfamily
G6N84_RS05800	COG1902	pentaerythritol trinitrate reductase activity
G6N84_RS05810	COG2824	Alkylphosphonate utilization operon protein PhnA
G6N84_RS05825	COG1047	Peptidyl-prolyl cis-trans
G6N84_RS05860	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G6N84_RS05875	COG1451	nucleotide metabolic process
G6N84_RS05895	COG0183	Belongs to the thiolase family
G6N84_RS05925	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
G6N84_RS05925	COG1793	dna ligase
G6N84_RS05935	COG1793	dna ligase
G6N84_RS05940	COG1201	RNA secondary structure unwinding
G6N84_RS05960	COG1278	Cold shock
G6N84_RS05965	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G6N84_RS05980	COG3046	protein related to deoxyribodipyrimidine photolyase
G6N84_RS05985	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
G6N84_RS05990	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G6N84_RS06005	COG2954	triphosphatase activity
G6N84_RS06020	COG1381	Involved in DNA repair and RecF pathway recombination
G6N84_RS06050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N84_RS06065	COG1024	Enoyl-CoA hydratase
G6N84_RS06065	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N84_RS06085	COG1024	Enoyl-CoA hydratase
G6N84_RS06090	COG1960	acyl-CoA dehydrogenase activity
G6N84_RS06110	COG3867	Arabinogalactan endo-beta-1,4-galactanase
G6N84_RS06150	COG3039	Transposase
G6N84_RS06170	COG2353	YceI-like domain
G6N84_RS06180	COG2353	YceI-like domain
G6N84_RS06195	COG1760	l-serine dehydratase
G6N84_RS06205	COG0626	cystathionine gamma-synthase activity
G6N84_RS06210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N84_RS06215	COG0739	heme binding
G6N84_RS06220	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G6N84_RS06225	COG1272	protein, Hemolysin III
G6N84_RS06250	COG0463	Glycosyl transferase, family 2
G6N84_RS06260	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G6N84_RS06270	COG4771	TonB-dependent receptor
G6N84_RS06275	COG1309	transcriptional regulator
G6N84_RS06285	COG1960	acyl-CoA dehydrogenase activity
G6N84_RS06320	COG0509	glycine decarboxylation via glycine cleavage system
G6N84_RS06335	COG0330	HflC and HflK could
G6N84_RS06350	COG3956	TIGRFAM MazG family protein
G6N84_RS06360	COG0494	nUDIX hydrolase
G6N84_RS06370	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G6N84_RS06375	COG0837	glucose binding
G6N84_RS06390	COG3858	chitin binding
G6N84_RS06390	COG1388	LysM domain
G6N84_RS06400	COG3525	Glycosyl hydrolase, family 20, catalytic domain
G6N84_RS06410	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N84_RS06440	COG3039	Transposase
G6N84_RS06455	COG3039	Transposase
G6N84_RS06480	COG3537	Alpha-1,2-mannosidase
G6N84_RS06530	COG3142	Participates in the control of copper homeostasis
G6N84_RS06535	COG1446	asparaginase
G6N84_RS06570	COG0643	Histidine kinase
G6N84_RS06570	COG0784	Response regulator, receiver
G6N84_RS06570	COG2198	Histidine kinase
G6N84_RS06575	COG0840	transmembrane signaling receptor activity
G6N84_RS06580	COG0835	chemotaxis
G6N84_RS06595	COG0189	ligase activity
G6N84_RS06605	COG1397	ADP-ribosylglycohydrolase
G6N84_RS06615	COG1199	ATP-dependent helicase activity
G6N84_RS06625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6N84_RS06630	COG1215	transferase activity, transferring glycosyl groups
G6N84_RS06640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G6N84_RS06690	COG1643	Atp-dependent helicase
G6N84_RS06695	COG0783	Belongs to the Dps family
G6N84_RS06700	COG0514	ATP-dependent DNA helicase (RecQ)
G6N84_RS06770	COG4695	Portal protein
G6N84_RS06815	COG3179	chitinase
G6N84_RS06990	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G6N84_RS07020	COG0602	queuosine metabolic process
G6N84_RS07030	COG2885	chlorophyll binding
G6N84_RS07045	COG0848	biopolymer transport protein
G6N84_RS07055	COG0824	Thioesterase
G6N84_RS07060	COG2255	four-way junction helicase activity
G6N84_RS07070	COG0632	four-way junction helicase activity
G6N84_RS07180	COG3209	COG3209 Rhs family protein
G6N84_RS07195	COG3209	COG3209 Rhs family protein
G6N84_RS07195	COG3209	COG3209 Rhs family protein
G6N84_RS07205	COG3501	Rhs element vgr protein
G6N84_RS07215	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G6N84_RS07220	COG1845	cytochrome c oxidase, subunit III
G6N84_RS07225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G6N84_RS07240	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G6N84_RS07245	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G6N84_RS07255	COG0196	riboflavin kinase activity
G6N84_RS07260	COG0728	peptidoglycan biosynthetic process
G6N84_RS07265	COG0268	Binds directly to 16S ribosomal RNA
G6N84_RS07270	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G6N84_RS07275	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G6N84_RS07285	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G6N84_RS07290	COG0824	Thioesterase
G6N84_RS07305	COG1946	Acyl-CoA thioesterase
G6N84_RS07315	COG1595	DNA-templated transcription, initiation
G6N84_RS07370	COG1877	trehalose-phosphatase activity
G6N84_RS07375	COG3387	PFAM Glycoside hydrolase 15-related
G6N84_RS07400	COG0564	pseudouridine synthase activity
G6N84_RS07405	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6N84_RS07410	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G6N84_RS07410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6N84_RS07425	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G6N84_RS07430	COG0045	succinate-CoA ligase (ADP-forming) activity
G6N84_RS07470	COG2194	sulfuric ester hydrolase activity
G6N84_RS07475	COG4969	Belongs to the N-Me-Phe pilin family
G6N84_RS07485	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G6N84_RS07530	COG3039	Transposase
G6N84_RS07560	COG3039	Transposase
G6N84_RS07575	COG3039	Transposase
G6N84_RS07620	COG1132	(ABC) transporter
G6N84_RS07650	COG0745	RESPONSE REGULATOR receiver
G6N84_RS07655	COG5000	phosphorelay sensor kinase activity
G6N84_RS07655	COG5002	protein histidine kinase activity
G6N84_RS07660	COG0475	glutathione-regulated potassium exporter activity
G6N84_RS07670	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G6N84_RS07690	COG1187	pseudouridine synthase activity
G6N84_RS07695	COG5001	Diguanylate cyclase
G6N84_RS07695	COG5002	protein histidine kinase activity
G6N84_RS07795	COG1028	Short-chain dehydrogenase reductase Sdr
G6N84_RS07810	COG0415	Belongs to the DNA photolyase family
G6N84_RS07815	COG0305	Participates in initiation and elongation during chromosome replication
G6N84_RS07825	COG0367	asparagine synthase
G6N84_RS07840	COG1960	acyl-CoA dehydrogenase activity
G6N84_RS07855	COG0084	hydrolase, TatD family'
G6N84_RS07860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G6N84_RS07920	COG0735	belongs to the Fur family
G6N84_RS07925	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6N84_RS07955	COG3039	Transposase
G6N84_RS07965	COG3039	Transposase
G6N84_RS07985	COG3039	Transposase
G6N84_RS08010	COG2205	protein histidine kinase activity
G6N84_RS08020	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G6N84_RS08030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G6N84_RS08045	COG0643	Histidine kinase
G6N84_RS08045	COG2198	Histidine kinase
G6N84_RS08050	COG0840	transmembrane signaling receptor activity
G6N84_RS08055	COG0835	chemotaxis
G6N84_RS08060	COG2202	Pas domain
G6N84_RS08060	COG2200	EAL domain
G6N84_RS08060	COG2199	diguanylate cyclase activity
G6N84_RS08065	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G6N84_RS08080	COG3590	peptidase
G6N84_RS08100	COG1515	deoxyribonuclease V activity
G6N84_RS08110	COG1741	Belongs to the pirin family
G6N84_RS08130	COG3039	Transposase
G6N84_RS08145	COG3501	Rhs element vgr protein
G6N84_RS08175	COG3501	Rhs element vgr protein
G6N84_RS08195	COG3501	Rhs element vgr protein
G6N84_RS08205	COG1741	Belongs to the pirin family
G6N84_RS08210	COG1966	Carbon starvation protein
G6N84_RS08215	COG2879	small protein
G6N84_RS08250	COG3706	GGDEF domain
G6N84_RS08250	COG4251	negative regulation of phosphorylation
G6N84_RS08250	COG5001	Diguanylate cyclase
G6N84_RS08250	COG2203	Gaf domain
G6N84_RS08255	COG0629	single-stranded DNA binding
G6N84_RS08260	COG0142	geranyltranstransferase activity
G6N84_RS08285	COG0527	aspartate kinase activity
G6N84_RS08295	COG0384	phenazine biosynthesis protein PhzF
G6N84_RS08305	COG1764	response to oxidative stress
G6N84_RS08320	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G6N84_RS08325	COG1678	Uncharacterized ACR, COG1678
G6N84_RS08335	COG0519	Catalyzes the synthesis of GMP from XMP
G6N84_RS08365	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G6N84_RS08405	COG0693	protein deglycase activity
G6N84_RS08425	COG1959	2 iron, 2 sulfur cluster binding
G6N84_RS08430	COG0719	Fe-S assembly protein
G6N84_RS08435	COG0396	ATPase activity
G6N84_RS08440	COG0719	Fe-S assembly protein
G6N84_RS08445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6N84_RS08455	COG2146	nitrite reductase [NAD(P)H] activity
G6N84_RS08490	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G6N84_RS08505	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G6N84_RS08515	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
G6N84_RS08520	COG0174	glutamine synthetase
G6N84_RS08525	COG3328	transposase activity
G6N84_RS08550	COG0326	Molecular chaperone. Has ATPase activity
G6N84_RS08555	COG2207	Transcriptional regulator
G6N84_RS08590	COG2755	lipolytic protein G-D-S-L family
G6N84_RS08590	COG0657	acetylesterase activity
G6N84_RS08615	COG0488	(ABC) transporter
G6N84_RS08650	COG4651	solute:proton antiporter activity
G6N84_RS08650	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6N84_RS08665	COG4772	TonB-dependent receptor
G6N84_RS08675	COG4264	IucA IucC family
G6N84_RS08680	COG2814	Major facilitator Superfamily
G6N84_RS08690	COG0019	diaminopimelate decarboxylase activity
G6N84_RS08750	COG4206	TonB-dependent receptor
G6N84_RS08785	COG0542	response to heat
G6N84_RS08820	COG0534	Mate efflux family protein
G6N84_RS08835	COG0336	Belongs to the RNA methyltransferase TrmD family
G6N84_RS08840	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G6N84_RS08845	COG0228	four-way junction DNA binding
G6N84_RS08865	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G6N84_RS08875	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G6N84_RS08920	COG1555	photosystem II stabilization
G6N84_RS08930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6N84_RS08945	COG3178	'Phosphotransferase
G6N84_RS08950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G6N84_RS08960	COG0628	permease
G6N84_RS08970	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G6N84_RS08985	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G6N84_RS09005	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G6N84_RS09010	COG0271	Belongs to the BolA IbaG family
G6N84_RS09020	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G6N84_RS09030	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G6N84_RS09035	COG1137	ATPase activity
G6N84_RS09050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6N84_RS09055	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
G6N84_RS09060	COG1660	Displays ATPase and GTPase activities
G6N84_RS09070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6N84_RS09075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6N84_RS09080	COG2239	Acts as a magnesium transporter
G6N84_RS09090	COG1294	oxidase, subunit
G6N84_RS09095	COG1271	oxidase subunit
G6N84_RS09110	COG1113	amino acid transport
G6N84_RS09125	COG2197	response regulator
G6N84_RS09130	COG0531	amino acid
G6N84_RS09190	COG0754	glutathionylspermidine amidase activity
G6N84_RS09215	COG1842	Phage shock protein A
G6N84_RS09230	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G6N84_RS09235	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G6N84_RS09245	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G6N84_RS09275	COG2201	protein-glutamate methylesterase activity
G6N84_RS09380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6N84_RS09385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6N84_RS09410	COG3039	Transposase
G6N84_RS09425	COG0745	RESPONSE REGULATOR receiver
G6N84_RS09430	COG2205	protein histidine kinase activity
G6N84_RS09450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G6N84_RS09480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N84_RS09480	COG3453	Protein conserved in bacteria
G6N84_RS09485	COG0725	ABC transporter, periplasmic molybdate-binding protein
G6N84_RS09490	COG4149	molybdate abc transporter
G6N84_RS09495	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G6N84_RS09515	COG0642	Histidine kinase
G6N84_RS09520	COG0745	RESPONSE REGULATOR receiver
G6N84_RS09530	COG1028	Short-chain dehydrogenase reductase Sdr
G6N84_RS09565	COG1376	ErfK ybiS ycfS ynhG family protein
G6N84_RS09570	COG0739	heme binding
G6N84_RS09580	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G6N84_RS09585	COG1301	dicarboxylic acid transport
G6N84_RS09605	COG2304	oxidoreductase activity
G6N84_RS09625	COG0714	Associated with various cellular activities
G6N84_RS09675	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G6N84_RS09700	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G6N84_RS09710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G6N84_RS09735	COG1561	YicC-like family, N-terminal region
G6N84_RS09740	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G6N84_RS09755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G6N84_RS09795	COG0006	proline dipeptidase activity
G6N84_RS09820	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G6N84_RS09830	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G6N84_RS09840	COG2912	Transglutaminase-like superfamily
G6N84_RS09845	COG1773	rubredoxin
G6N84_RS09850	COG0352	thiamine-phosphate diphosphorylase activity
G6N84_RS09875	COG0281	malic enzyme
G6N84_RS09875	COG0280	phosphate acetyltransferase
G6N84_RS09895	COG4191	Histidine kinase
G6N84_RS09910	COG0583	DNA-binding transcription factor activity
G6N84_RS09925	COG2197	response regulator
G6N84_RS09935	COG0642	Histidine kinase
G6N84_RS09950	COG2851	Citrate transporter
G6N84_RS09955	COG1028	Short-chain dehydrogenase reductase Sdr
G6N84_RS09960	COG1609	Transcriptional regulator
G6N84_RS09970	COG2211	Major facilitator Superfamily
G6N84_RS10020	COG0726	polysaccharide deacetylase
G6N84_RS10025	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G6N84_RS10050	COG3039	Transposase
G6N84_RS10100	COG0242	peptide deformylase activity
G6N84_RS10120	COG0714	Associated with various cellular activities
G6N84_RS10140	COG0537	adenosine 5'-monophosphoramidase activity
G6N84_RS10170	COG0314	molybdopterin synthase activity
G6N84_RS10175	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G6N84_RS10180	COG0315	cyclic pyranopterin monophosphate synthase activity
G6N84_RS10190	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G6N84_RS10195	COG1234	tRNA 3'-trailer cleavage
G6N84_RS10200	COG3642	lipopolysaccharide core region biosynthetic process
G6N84_RS10205	COG0859	PFAM glycosyl transferase family 9
G6N84_RS10215	COG0582	viral genome integration into host DNA
G6N84_RS10260	COG3501	Rhs element vgr protein
G6N84_RS10285	COG0631	protein serine/threonine phosphatase activity
G6N84_RS10300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G6N84_RS10325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G6N84_RS10365	COG0544	peptidyl-prolyl cis-trans isomerase activity
G6N84_RS10415	COG0473	3-isopropylmalate dehydrogenase activity
G6N84_RS10440	COG0584	glycerophosphoryl diester phosphodiesterase
G6N84_RS10460	COG3039	Transposase
G6N84_RS10590	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G6N84_RS10615	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G6N84_RS10625	COG0625	glutathione transferase activity
G6N84_RS10640	COG3781	membrane
G6N84_RS10650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G6N84_RS10680	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
G6N84_RS10690	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
G6N84_RS10700	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G6N84_RS10725	COG3710	Transcriptional regulator
G6N84_RS10730	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G6N84_RS10740	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G6N84_RS10775	COG0066	3-isopropylmalate dehydratase activity
G6N84_RS10780	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G6N84_RS10810	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G6N84_RS10815	COG1538	Outer membrane efflux protein
G6N84_RS10820	COG1519	Transferase
G6N84_RS10825	COG1560	Kdo2-lipid A biosynthetic process
G6N84_RS10870	COG0308	aminopeptidase N
G6N84_RS10885	COG0330	HflC and HflK could
G6N84_RS10890	COG0330	HflC and HflK could
G6N84_RS10910	COG0678	peroxiredoxin activity
G6N84_RS10920	COG2826	transposase and inactivated derivatives, IS30 family
G6N84_RS11000	COG3829	transcription factor binding
G6N84_RS11035	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G6N84_RS11040	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G6N84_RS11050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6N84_RS11055	COG1028	Short-chain dehydrogenase reductase Sdr
G6N84_RS11080	COG1399	metal-binding, possibly nucleic acid-binding protein
G6N84_RS11125	COG1518	maintenance of DNA repeat elements
G6N84_RS11130	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
G6N84_RS11175	COG2188	Transcriptional regulator
G6N84_RS11190	COG1450	Type ii and iii secretion system protein
G6N84_RS11205	COG3166	PFAM Fimbrial assembly family protein
G6N84_RS11210	COG3156	type II secretion system protein K
G6N84_RS11215	COG4795	General secretion pathway protein
G6N84_RS11220	COG2165	general secretion pathway protein
G6N84_RS11225	COG4970	Tfp pilus assembly protein FimT
G6N84_RS11230	COG2165	general secretion pathway protein
G6N84_RS11235	COG1459	type II secretion system
G6N84_RS11245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G6N84_RS11255	COG5295	Hep Hag repeat protein
G6N84_RS11260	COG0047	phosphoribosylformylglycinamidine synthase activity
G6N84_RS11260	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G6N84_RS11265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G6N84_RS11270	COG4974	Belongs to the 'phage' integrase family
G6N84_RS11285	COG0795	lipopolysaccharide-transporting ATPase activity
G6N84_RS11295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G6N84_RS11310	COG0525	valine-tRNA ligase activity
G6N84_RS11365	COG3039	Transposase
G6N84_RS11395	COG1183	phosphatidylcholine synthase activity
G6N84_RS11405	COG0442	prolyl-tRNA aminoacylation
G6N84_RS11420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N84_RS11425	COG1127	ABC transporter
G6N84_RS11430	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N84_RS11430	COG3218	ABC-type transport auxiliary lipoprotein component
G6N84_RS11465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N84_RS11470	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
G6N84_RS11470	COG0662	Cupin 2, conserved barrel domain protein
G6N84_RS11495	COG2086	electron transfer activity
G6N84_RS11520	COG3328	transposase activity
G6N84_RS11560	COG0626	cystathionine gamma-synthase activity
G6N84_RS11605	COG0513	Belongs to the DEAD box helicase family
G6N84_RS11610	COG0720	synthase
G6N84_RS11620	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G6N84_RS11625	COG1956	GAF domain-containing protein
G6N84_RS11660	COG0339	signal peptide processing
G6N84_RS11705	COG3039	Transposase
G6N84_RS11725	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G6N84_RS11730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6N84_RS11780	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G6N84_RS11785	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G6N84_RS11790	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G6N84_RS11795	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G6N84_RS11805	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G6N84_RS11815	COG0356	it plays a direct role in the translocation of protons across the membrane
G6N84_RS11835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G6N84_RS11845	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N84_RS11875	COG2011	ABC-type metal ion transport system permease component
G6N84_RS11885	COG0697	spore germination
G6N84_RS11920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6N84_RS11925	COG1187	pseudouridine synthase activity
G6N84_RS11930	COG2813	Specifically methylates the guanine in position
G6N84_RS11960	COG2205	protein histidine kinase activity
G6N84_RS11960	COG2202	Pas domain
G6N84_RS11985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6N84_RS12035	COG0745	RESPONSE REGULATOR receiver
G6N84_RS12050	COG1404	Belongs to the peptidase S8 family
G6N84_RS12065	COG0842	Transport permease protein
G6N84_RS12070	COG1131	(ABC) transporter
G6N84_RS12075	COG0025	NhaP-type Na H and K H
G6N84_RS12095	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
G6N84_RS12105	COG1573	uracil-dna glycosylase
G6N84_RS12115	COG3384	dioxygenase
G6N84_RS12130	COG0667	Aldo Keto reductase
G6N84_RS12140	COG3590	peptidase
G6N84_RS12160	COG0531	amino acid
G6N84_RS12185	COG2972	Histidine kinase
G6N84_RS12240	COG1271	oxidase subunit
G6N84_RS12245	COG1294	oxidase, subunit
G6N84_RS12405	COG3039	Transposase
G6N84_RS12470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G6N84_RS12480	COG1560	Kdo2-lipid A biosynthetic process
G6N84_RS12530	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G6N84_RS12530	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G6N84_RS12535	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G6N84_RS12540	COG0242	peptide deformylase activity
G6N84_RS12545	COG1652	LysM domain
G6N84_RS12550	COG0758	DNA mediated transformation
G6N84_RS12555	COG2922	Belongs to the Smg family
G6N84_RS12570	COG1754	DNA topoisomerase type I activity
G6N84_RS12570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G6N84_RS12575	COG0009	L-threonylcarbamoyladenylate synthase
G6N84_RS12590	COG1028	Short-chain dehydrogenase reductase Sdr
G6N84_RS12600	COG0616	signal peptide processing
G6N84_RS12605	COG0534	Mate efflux family protein
G6N84_RS12625	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G6N84_RS12660	COG1324	tolerance protein
G6N84_RS12670	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G6N84_RS12675	COG0511	ligase activity, forming carbon-carbon bonds
G6N84_RS12685	COG0439	Biotin carboxylase
G6N84_RS12730	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G6N84_RS12750	COG2267	carboxylic ester hydrolase activity
G6N84_RS12755	COG2267	carboxylic ester hydrolase activity
G6N84_RS12760	COG2267	carboxylic ester hydrolase activity
G6N84_RS12775	COG0419	ATPase involved in DNA repair
G6N84_RS12785	COG0151	Belongs to the GarS family
G6N84_RS12790	COG0577	efflux transmembrane transporter activity
G6N84_RS12790	COG1136	(ABC) transporter
G6N84_RS12800	COG1289	transmembrane transporter activity
G6N84_RS12815	COG2814	Major facilitator Superfamily
G6N84_RS12830	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G6N84_RS12865	COG0745	RESPONSE REGULATOR receiver
G6N84_RS12910	COG0739	heme binding
G6N84_RS12925	COG2211	Major facilitator Superfamily
G6N84_RS12930	COG0708	Exodeoxyribonuclease III
G6N84_RS12945	COG1192	Involved in chromosome partitioning
G6N84_RS12950	COG1475	DNA binding
G6N84_RS12965	COG0463	Glycosyl transferase, family 2
G6N84_RS12985	COG0756	dUTP diphosphatase activity
G6N84_RS12990	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G6N84_RS12995	COG2003	Belongs to the UPF0758 family
G6N84_RS13000	COG0018	arginyl-trna synthetase
G6N84_RS13015	COG4221	oxidoreductase activity
G6N84_RS13040	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N84_RS13045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N84_RS13060	COG3485	protocatechuate 3,4-dioxygenase
G6N84_RS13065	COG3485	protocatechuate 3,4-dioxygenase
G6N84_RS13100	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G6N84_RS13105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G6N84_RS13115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6N84_RS13115	COG1042	CoA-binding domain protein
G6N84_RS13115	COG0045	succinate-CoA ligase (ADP-forming) activity
G6N84_RS13130	COG2239	Acts as a magnesium transporter
G6N84_RS13145	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G6N84_RS13150	COG3387	PFAM Glycoside hydrolase 15-related
G6N84_RS13165	COG3100	YcgL domain-containing protein
G6N84_RS13170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G6N84_RS13180	COG0463	Glycosyl transferase, family 2
G6N84_RS13195	COG1028	Short-chain dehydrogenase reductase Sdr
G6N84_RS13205	COG0156	8-amino-7-oxononanoate synthase activity
G6N84_RS13210	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G6N84_RS13215	COG1040	competence protein
G6N84_RS13220	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G6N84_RS13230	COG0628	permease
G6N84_RS13240	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G6N84_RS13250	COG1595	DNA-templated transcription, initiation
G6N84_RS13255	COG0753	catalase activity
G6N84_RS13300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N84_RS13305	COG0180	Tryptophanyl-tRNA synthetase
G6N84_RS13310	COG3237	CsbD-like
G6N84_RS13345	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G6N84_RS13360	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G6N84_RS13365	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
G6N84_RS13365	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
G6N84_RS13390	COG2205	protein histidine kinase activity
G6N84_RS13395	COG0745	RESPONSE REGULATOR receiver
G6N84_RS13405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G6N84_RS13425	COG1566	PFAM secretion protein HlyD family protein
G6N84_RS13445	COG1199	ATP-dependent helicase activity
G6N84_RS13485	COG0583	DNA-binding transcription factor activity
G6N84_RS13530	COG0625	glutathione transferase activity
G6N84_RS13570	COG4555	ABC transporter
G6N84_RS13580	COG1476	TRANSCRIPTIONal
G6N84_RS13605	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G6N84_RS13610	COG1131	(ABC) transporter
G6N84_RS13615	COG0842	Transport permease protein
G6N84_RS13625	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G6N84_RS13710	COG1181	Belongs to the D-alanine--D-alanine ligase family
G6N84_RS13720	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N84_RS13730	COG0564	pseudouridine synthase activity
G6N84_RS13760	COG0339	signal peptide processing
G6N84_RS13790	COG3254	rhamnose metabolic process
G6N84_RS13795	COG0738	Major facilitator superfamily
G6N84_RS13800	COG1414	Transcriptional regulator
G6N84_RS13810	COG2205	protein histidine kinase activity
G6N84_RS13820	COG3459	Glycosyltransferase 36 associated
G6N84_RS13825	COG2211	Major facilitator Superfamily
G6N84_RS13830	COG3265	gluconokinase activity
G6N84_RS13840	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6N84_RS13915	COG1127	ABC transporter
G6N84_RS13920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N84_RS13925	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N84_RS13940	COG2853	Lipoprotein
G6N84_RS13960	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G6N84_RS14025	COG0676	glucose-6-phosphate 1-epimerase activity
G6N84_RS14050	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
G6N84_RS14060	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
G6N84_RS14070	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
G6N84_RS14075	COG1064	alcohol dehydrogenase
G6N84_RS14120	COG1522	sequence-specific DNA binding
G6N84_RS14125	COG3186	Phenylalanine-4-hydroxylase
G6N84_RS14170	COG2937	Belongs to the GPAT DAPAT family
G6N84_RS14205	COG0284	orotidine-5'-phosphate decarboxylase activity
G6N84_RS14210	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
G6N84_RS14215	COG3132	Protein of unknown function, DUF480
G6N84_RS14230	COG0210	DNA helicase
G6N84_RS14245	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
G6N84_RS14270	COG1028	Short-chain dehydrogenase reductase Sdr
G6N84_RS14345	COG3501	Rhs element vgr protein
G6N84_RS14355	COG1166	arginine decarboxylase activity
G6N84_RS14360	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G6N84_RS14400	COG0606	chelatase, subunit chli
G6N84_RS14445	COG0366	Alpha amylase catalytic
G6N84_RS14450	COG0366	Alpha amylase catalytic
G6N84_RS14475	COG1609	Transcriptional regulator
G6N84_RS14515	COG0493	'glutamate synthase
G6N84_RS14520	COG0070	glutamate synthase
G6N84_RS14520	COG0069	glutamate synthase activity
G6N84_RS14520	COG0067	glutamate synthase
G6N84_RS14580	COG1205	dead DEAH box helicase
G6N84_RS14580	COG1111	helicase
G6N84_RS14585	COG1272	protein, Hemolysin III
G6N84_RS14625	COG1136	(ABC) transporter
G6N84_RS14665	COG3039	Transposase
G6N84_RS14675	COG3039	Transposase
G6N84_RS14685	COG1136	(ABC) transporter
G6N84_RS14730	COG3039	Transposase
G6N84_RS14735	COG0513	Belongs to the DEAD box helicase family
G6N84_RS14835	COG1858	cytochrome C peroxidase
G6N84_RS14850	COG0702	epimerase
G6N84_RS14875	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G6N84_RS14900	COG2354	Protein conserved in bacteria
G6N84_RS14905	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N84_RS14920	COG3264	Mechanosensitive ion channel
G6N84_RS14920	COG1511	domain protein
G6N84_RS14995	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G6N84_RS15070	COG3039	Transposase
G6N84_RS15080	COG3039	Transposase
G6N84_RS15115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N84_RS15125	COG0642	Histidine kinase
G6N84_RS15135	COG1090	epimerase
G6N84_RS15145	COG3039	Transposase
G6N84_RS15170	COG2826	transposase and inactivated derivatives, IS30 family
G6N84_RS15255	COG3039	Transposase
G6N84_RS15265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N84_RS15275	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G6N84_RS15290	COG1755	Isoprenylcysteine carboxyl methyltransferase
G6N84_RS15295	COG1304	FMN binding
G6N84_RS15300	COG3039	Transposase
G6N84_RS15315	COG4772	TonB-dependent receptor
G6N84_RS15325	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G6N84_RS15335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G6N84_RS15345	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G6N84_RS15375	COG0501	Belongs to the peptidase M48B family
G6N84_RS15385	COG0187	DNA topoisomerase II activity
G6N84_RS15400	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G6N84_RS15420	COG0726	polysaccharide deacetylase
G6N84_RS15430	COG0671	phosphoesterase, PA-phosphatase related
G6N84_RS15440	COG0584	glycerophosphoryl diester phosphodiesterase
G6N84_RS15450	COG0861	Integral membrane protein TerC family
G6N84_RS15455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G6N84_RS15470	COG2271	Major facilitator Superfamily
G6N84_RS15475	COG1929	Belongs to the glycerate kinase type-1 family
G6N84_RS15565	COG0477	Major facilitator Superfamily
G6N84_RS15585	COG0302	gtp cyclohydrolase
G6N84_RS15590	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G6N84_RS15635	COG2234	aminopeptidase activity
G6N84_RS15645	COG4942	peptidase
G6N84_RS15650	COG0793	Belongs to the peptidase S41A family
G6N84_RS15700	COG0386	Belongs to the glutathione peroxidase family
G6N84_RS15710	COG1322	Protein conserved in bacteria
G6N84_RS15715	COG0531	amino acid
G6N84_RS15730	COG0210	DNA helicase
G6N84_RS15745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G6N84_RS15750	COG0583	DNA-binding transcription factor activity
G6N84_RS15755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G6N84_RS15775	COG2159	amidohydrolase
G6N84_RS15800	COG0357	Ribosomal RNA small subunit methyltransferase G
G6N84_RS15805	COG3540	Alkaline phosphatase
G6N84_RS15815	COG2091	lysine biosynthetic process via aminoadipic acid
G6N84_RS15830	COG0708	Exodeoxyribonuclease III
G6N84_RS15845	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G6N84_RS15850	COG3162	membrane
G6N84_RS15890	COG3507	Belongs to the glycosyl hydrolase 43 family
G6N84_RS15910	COG1028	Short-chain dehydrogenase reductase Sdr
G6N84_RS15915	COG0179	Fumarylacetoacetate (FAA) hydrolase
G6N84_RS15920	COG4948	Mandelate Racemase Muconate Lactonizing
G6N84_RS15925	COG4807	Protein conserved in bacteria
G6N84_RS15930	COG1643	Atp-dependent helicase
G6N84_RS15940	COG1187	pseudouridine synthase activity
G6N84_RS15950	COG0667	Aldo Keto reductase
G6N84_RS15955	COG2130	NADP-dependent
G6N84_RS15960	COG0656	L-ascorbic acid biosynthetic process
G6N84_RS15995	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6N84_RS16005	COG1119	ATPase activity
G6N84_RS16020	COG0517	IMP dehydrogenase activity
G6N84_RS16020	COG1125	glycine betaine transport
G6N84_RS16035	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N84_RS16040	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
G6N84_RS16045	COG3550	peptidyl-serine autophosphorylation
G6N84_RS16050	COG1396	sequence-specific DNA binding
G6N84_RS16070	COG0489	protein tyrosine kinase activity
G6N84_RS16075	COG2062	phosphohistidine phosphatase, SixA
G6N84_RS16085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G6N84_RS16130	COG1968	undecaprenyl-diphosphatase activity
G6N84_RS16135	COG0174	glutamine synthetase
G6N84_RS16140	COG0347	Belongs to the P(II) protein family
G6N84_RS16145	COG0004	ammonium transporteR
G6N84_RS16150	COG3852	Histidine kinase
G6N84_RS16155	COG2204	response regulator
G6N84_RS16160	COG2032	superoxide dismutase activity
G6N84_RS16165	COG2032	superoxide dismutase activity
G6N84_RS16205	COG1196	nuclear chromosome segregation
G6N84_RS16215	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G6N84_RS16220	COG1074	ATP-dependent DNA helicase activity
G6N84_RS16225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G6N84_RS16230	COG3549	Plasmid maintenance system killer
G6N84_RS16310	COG1764	response to oxidative stress
G6N84_RS16315	COG1846	Transcriptional regulator
G6N84_RS16360	COG4943	cyclic-guanylate-specific phosphodiesterase activity
G6N84_RS16405	COG2211	Major facilitator Superfamily
G6N84_RS16425	COG3693	PFAM glycoside hydrolase, family 10
G6N84_RS16450	COG0246	Mannitol dehydrogenase
G6N84_RS16455	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N84_RS16465	COG4948	Mandelate Racemase Muconate Lactonizing
G6N84_RS16475	COG3661	Belongs to the glycosyl hydrolase 67 family
G6N84_RS16495	COG2974	May be involved in recombination
G6N84_RS16520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G6N84_RS16530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G6N84_RS16540	COG0805	protein transport
G6N84_RS16550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G6N84_RS16550	COG0519	Catalyzes the synthesis of GMP from XMP
G6N84_RS16565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G6N84_RS16570	COG0752	glycyl-tRNA synthetase alpha subunit
G6N84_RS16580	COG0457	Tetratricopeptide repeat
G6N84_RS16585	COG4771	TonB-dependent receptor
G6N84_RS16600	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G6N84_RS16610	COG0697	spore germination
G6N84_RS16620	COG0523	cobalamin synthesis protein
G6N84_RS16670	COG1960	acyl-CoA dehydrogenase activity
G6N84_RS16675	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N84_RS16680	COG4770	biotin carboxylase activity
G6N84_RS16730	COG2072	flavoprotein involved in K transport
G6N84_RS16750	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G6N84_RS16795	COG0084	hydrolase, TatD family'
G6N84_RS16810	COG0583	DNA-binding transcription factor activity
G6N84_RS16815	COG2814	Major facilitator Superfamily
G6N84_RS16825	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G6N84_RS16830	COG1902	pentaerythritol trinitrate reductase activity
G6N84_RS16860	COG0745	RESPONSE REGULATOR receiver
G6N84_RS16880	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G6N84_RS16885	COG0583	DNA-binding transcription factor activity
G6N84_RS16915	COG0702	epimerase
G6N84_RS16920	COG1733	regulation of RNA biosynthetic process
G6N84_RS16970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6N84_RS16985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G6N84_RS17020	COG2911	Protein conserved in bacteria
G6N84_RS17025	COG0729	surface antigen
G6N84_RS17040	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G6N84_RS17045	COG3118	belongs to the thioredoxin family
G6N84_RS17055	COG2884	Cell division ATP-binding protein ftsE
G6N84_RS17060	COG2177	Part of the ABC transporter FtsEX involved in
G6N84_RS17065	COG2201	protein-glutamate methylesterase activity
G6N84_RS17070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G6N84_RS17075	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G6N84_RS17085	COG1252	NADH dehydrogenase
G6N84_RS17115	COG0459	protein refolding
G6N84_RS17125	COG4771	TonB-dependent receptor
G6N84_RS17140	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G6N84_RS17180	COG3386	PFAM SMP-30 Gluconolaconase
G6N84_RS17195	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G6N84_RS17225	COG2353	YceI-like domain
G6N84_RS17270	COG2201	protein-glutamate methylesterase activity
G6N84_RS17280	COG3039	Transposase
G6N84_RS17305	COG3039	Transposase
G6N84_RS17365	COG0408	coproporphyrinogen oxidase activity
G6N84_RS17375	COG3039	Transposase
G6N84_RS17395	COG0129	dihydroxy-acid dehydratase activity
G6N84_RS17405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G6N84_RS17455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6N84_RS17460	COG0318	PFAM AMP-dependent synthetase and ligase
G6N84_RS17465	COG0727	PFAM Uncharacterised protein family (UPF0153)
G6N84_RS17470	COG0596	Alpha beta hydrolase
G6N84_RS17485	COG3177	Filamentation induced by cAMP protein fic
G6N84_RS17490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6N84_RS17505	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G6N84_RS17530	COG4191	Histidine kinase
G6N84_RS17535	COG0028	Belongs to the TPP enzyme family
G6N84_RS17550	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G6N84_RS17555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G6N84_RS17590	COG5383	Protein conserved in bacteria
G6N84_RS17605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6N84_RS17610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6N84_RS17615	COG1473	amidohydrolase
G6N84_RS17625	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G6N84_RS17625	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G6N84_RS17645	COG3039	Transposase
G6N84_RS17720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G6N84_RS17735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6N84_RS17740	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
G6N84_RS17750	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
G6N84_RS17755	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G6N84_RS17760	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G6N84_RS17810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G6N84_RS17825	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
G6N84_RS17890	COG0358	DNA primase activity
G6N84_RS17895	COG1295	ribonuclease BN
G6N84_RS17905	COG1610	YqeY-like protein
G6N84_RS17915	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G6N84_RS17920	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G6N84_RS17960	COG2133	pyrroloquinoline quinone binding
G6N84_RS17965	COG4682	membrane
G6N84_RS17990	COG0531	amino acid
G6N84_RS18020	COG4948	Mandelate Racemase Muconate Lactonizing
G6N84_RS18030	COG3023	N-Acetylmuramoyl-L-alanine amidase
G6N84_RS18035	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
G6N84_RS18105	COG0183	Belongs to the thiolase family
G6N84_RS18140	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G6N84_RS18150	COG3483	tryptophan 2,3-dioxygenase activity
G6N84_RS18155	COG3104	oligopeptide transport
G6N84_RS18185	COG1320	monovalent cation:proton antiporter activity
G6N84_RS18190	COG2212	antiporter activity
G6N84_RS18200	COG0651	ATP synthesis coupled electron transport
G6N84_RS18205	COG1006	Multisubunit Na H antiporter MnhC subunit
G6N84_RS18210	COG2111	Na H antiporter
G6N84_RS18210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G6N84_RS18250	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G6N84_RS18260	COG0456	acetyltransferase
G6N84_RS18290	COG4221	oxidoreductase activity
G6N84_RS18345	COG0697	spore germination
G6N84_RS18350	COG4305	rare lipoprotein A
G6N84_RS18355	COG5297	Belongs to the glycosyl hydrolase family 6
G6N84_RS18365	COG1113	amino acid transport
G6N84_RS18375	COG0598	Magnesium transport protein CorA
G6N84_RS18445	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
G6N84_RS18445	COG5297	Belongs to the glycosyl hydrolase family 6
G6N84_RS18450	COG0659	secondary active sulfate transmembrane transporter activity
G6N84_RS18485	COG3275	phosphorelay sensor kinase activity
G6N84_RS18520	COG1505	serine-type exopeptidase activity
G6N84_RS18565	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G6N84_RS18595	COG0308	aminopeptidase N
G6N84_RS18600	COG2199	diguanylate cyclase activity
G6N84_RS18650	COG3039	Transposase
G6N84_RS18655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N84_RS18660	COG1077	Cell shape determining protein MreB Mrl
G6N84_RS18665	COG1792	Involved in formation and maintenance of cell shape
G6N84_RS18680	COG0772	Belongs to the SEDS family
G6N84_RS18705	COG3501	Rhs element vgr protein
G6N84_RS18720	COG3409	Peptidoglycan-binding domain 1 protein
G6N84_RS18720	COG5632	N-Acetylmuramoyl-L-alanine amidase
G6N84_RS18720	COG1388	LysM domain
G6N84_RS18740	COG2951	lytic endotransglycosylase activity
G6N84_RS18745	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G6N84_RS18750	COG1686	Belongs to the peptidase S11 family
G6N84_RS18765	COG2921	Belongs to the UPF0250 family
G6N84_RS18800	COG1051	belongs to the nudix hydrolase family
G6N84_RS18800	COG1056	cytidyltransferase-related domain
G6N84_RS18835	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G6N84_RS18840	COG0673	inositol 2-dehydrogenase activity
G6N84_RS18845	COG2823	Periplasmic or secreted lipoprotein
G6N84_RS18850	COG4251	negative regulation of phosphorylation
G6N84_RS18855	COG0784	Response regulator, receiver
G6N84_RS18860	COG4191	Histidine kinase
G6N84_RS18865	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G6N84_RS18915	COG3250	beta-galactosidase activity
G6N84_RS18930	COG2188	Transcriptional regulator
G6N84_RS18940	COG1609	Transcriptional regulator
G6N84_RS18945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G6N84_RS18950	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G6N84_RS18960	COG1215	transferase activity, transferring glycosyl groups
G6N84_RS18965	COG1649	PFAM Uncharacterised BCR, COG1649
G6N84_RS18965	COG0726	polysaccharide deacetylase
G6N84_RS19000	COG3039	Transposase
G6N84_RS19055	COG3039	Transposase
G6N84_RS19075	COG3039	Transposase
G6N84_RS19110	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G6N84_RS19130	COG2205	protein histidine kinase activity
G6N84_RS19165	COG2205	protein histidine kinase activity
G6N84_RS19170	COG0745	RESPONSE REGULATOR receiver
G6N84_RS19215	COG0488	(ABC) transporter
G6N84_RS19235	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G6N84_RS19255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6N84_RS19255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6N84_RS19275	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G6N84_RS19280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G6N84_RS19285	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G6N84_RS19305	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
G6N84_RS19310	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G6N84_RS19320	COG2205	protein histidine kinase activity
G6N84_RS19325	COG0745	RESPONSE REGULATOR receiver
G6N84_RS19330	COG0277	FAD linked oxidase domain protein
G6N84_RS19335	COG1988	membrane-bound metal-dependent
G6N84_RS19340	COG0792	nuclease activity
G6N84_RS19385	COG3116	cell division
G6N84_RS19400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G6N84_RS19420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G6N84_RS19425	COG1181	Belongs to the D-alanine--D-alanine ligase family
G6N84_RS19430	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G6N84_RS19445	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G6N84_RS19455	COG1388	LysM domain
G6N84_RS19455	COG4942	peptidase
G6N84_RS19470	COG0494	nUDIX hydrolase
G6N84_RS19490	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G6N84_RS19500	COG3321	synthase
G6N84_RS19500	COG1028	Short-chain dehydrogenase reductase Sdr
G6N84_RS19500	COG0604	alcohol dehydrogenase
G6N84_RS19545	COG2226	methyltransferase
G6N84_RS19550	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G6N84_RS19600	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G6N84_RS19615	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G6N84_RS19625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N84_RS19630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G6N84_RS19640	COG0667	Aldo Keto reductase
G6N84_RS19695	COG2175	clavaminate synthase activity
G6N84_RS19705	COG4181	ATPase activity
G6N84_RS19720	COG0642	Histidine kinase
G6N84_RS19745	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G6N84_RS19765	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G6N84_RS19790	COG2967	ApaG domain
G6N84_RS19795	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G6N84_RS19805	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G6N84_RS19820	COG0123	including yeast histone deacetylase and acetoin utilization protein
G6N84_RS19825	COG2096	Adenosyltransferase
G6N84_RS19835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N84_RS19840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N84_RS19880	COG0583	DNA-binding transcription factor activity
G6N84_RS19885	COG0318	PFAM AMP-dependent synthetase and ligase
G6N84_RS19895	COG1024	Enoyl-CoA hydratase
G6N84_RS20035	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6N84_RS20035	COG1902	pentaerythritol trinitrate reductase activity
G6N84_RS20040	COG0604	alcohol dehydrogenase
G6N84_RS20065	COG0156	8-amino-7-oxononanoate synthase activity
G6N84_RS20070	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G6N84_RS20075	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G6N84_RS20080	COG4208	sulfate ABC transporter
G6N84_RS20085	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G6N84_RS20115	COG0588	phosphoglycerate mutase activity
G6N84_RS20125	COG0285	dihydrofolate synthase activity
G6N84_RS20145	COG2833	Protein of unknown function (DUF455)
G6N84_RS20165	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G6N84_RS20170	COG0671	phosphoesterase, PA-phosphatase related
G6N84_RS20175	COG0438	transferase activity, transferring glycosyl groups
G6N84_RS20185	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G6N84_RS20200	COG4783	chaperone-mediated protein folding
G6N84_RS20235	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N84_RS20265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G6N84_RS20270	COG0583	DNA-binding transcription factor activity
G6N84_RS20275	COG3634	alkyl hydroperoxide reductase activity
G6N84_RS20285	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N84_RS20325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G6N84_RS20325	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G6N84_RS20340	COG3039	Transposase
G6N84_RS20350	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
G6N84_RS20375	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
G6N84_RS20400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G6N84_RS20410	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G6N84_RS20440	COG1295	ribonuclease BN
G6N84_RS20445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6N84_RS20465	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6N84_RS20475	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G6N84_RS20480	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G6N84_RS20490	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
G6N84_RS20505	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G6N84_RS20515	COG0193	aminoacyl-tRNA hydrolase activity
G6N84_RS20520	COG0012	GTP binding
G6N84_RS20550	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G6N84_RS20555	COG0250	Participates in transcription elongation, termination and antitermination
G6N84_RS20560	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G6N84_RS20570	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G6N84_RS20575	COG0222	ribosome binding
G6N84_RS20580	COG0085	RNA polymerase activity
G6N84_RS20585	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G6N84_RS20590	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G6N84_RS20595	COG0049	tRNA binding
G6N84_RS20615	COG0051	transcription antitermination factor activity, RNA binding
G6N84_RS20620	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G6N84_RS20625	COG0088	Forms part of the polypeptide exit tunnel
G6N84_RS20630	COG0089	rRNA binding
G6N84_RS20645	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G6N84_RS20655	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G6N84_RS20660	COG0255	Belongs to the universal ribosomal protein uL29 family
G6N84_RS20665	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G6N84_RS20670	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G6N84_RS20680	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G6N84_RS20710	COG1841	ribosomal large subunit assembly
G6N84_RS20720	COG0201	protein transport
G6N84_RS20730	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G6N84_RS20735	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G6N84_RS20835	COG2194	sulfuric ester hydrolase activity
G6N84_RS20845	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6N84_RS20850	COG0745	RESPONSE REGULATOR receiver
G6N84_RS20855	COG0642	Histidine kinase
G6N84_RS20865	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G6N84_RS20870	COG2894	cell division
G6N84_RS20885	COG4585	Histidine kinase
G6N84_RS20890	COG2197	response regulator
G6N84_RS20905	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
G6N84_RS20990	COG3501	Rhs element vgr protein
G6N84_RS21040	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N84_RS21045	COG3501	Rhs element vgr protein
G6N84_RS21050	COG3501	Rhs element vgr protein
G6N84_RS21145	COG3501	Rhs element vgr protein
G6N84_RS21160	COG3501	Rhs element vgr protein
G6N84_RS21170	COG3179	chitinase
G6N84_RS21175	COG3501	Rhs element vgr protein
G6N84_RS21240	COG3501	Rhs element vgr protein
G6N84_RS21265	COG3501	Rhs element vgr protein
G6N84_RS21340	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
G6N84_RS21360	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G6N84_RS21365	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
G6N84_RS21370	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
G6N84_RS21385	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G6N84_RS21480	COG1297	OPT oligopeptide transporter protein
G6N84_RS21500	COG1506	peptidase
G6N84_RS21500	COG0823	Involved in the tonB-independent uptake of proteins
G6N84_RS21520	COG2207	Transcriptional regulator
G6N84_RS21520	COG1917	Cupin 2, conserved barrel domain protein
G6N84_RS21545	COG0753	catalase activity
G6N84_RS21585	COG0469	pyruvate kinase activity
G6N84_RS21590	COG3588	fructose-bisphosphate aldolase
G6N84_RS21595	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
G6N84_RS21645	COG0784	Response regulator, receiver
G6N84_RS21645	COG2198	Histidine kinase
G6N84_RS21645	COG2205	protein histidine kinase activity
G6N84_RS21665	COG0175	sulfate reduction
G6N84_RS21670	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6N84_RS21675	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G6N84_RS21680	COG0175	sulfate reduction
G6N84_RS21685	COG2895	sulfate adenylyltransferase (ATP) activity
G6N84_RS21685	COG0529	Catalyzes the synthesis of activated sulfate
G6N84_RS21695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6N84_RS21700	COG0308	aminopeptidase N
G6N84_RS21725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6N84_RS21750	COG1970	mechanosensitive ion channel activity
G6N84_RS21780	COG3273	potassium ion transport
G6N84_RS21780	COG0471	metal ion transport
G6N84_RS21790	COG2022	thiamine diphosphate biosynthetic process
G6N84_RS21870	COG3039	Transposase
G6N84_RS21875	COG3039	Transposase
G6N84_RS21945	COG3118	belongs to the thioredoxin family
G6N84_RS21970	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G6N84_RS21995	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G6N84_RS22025	COG2968	Membrane
G6N84_RS22035	COG1530	ribonuclease E activity
G6N84_RS22040	COG3164	Protein of unknown function
G6N84_RS22070	COG0312	modulator of DNA gyrase
G6N84_RS22080	COG0312	modulator of DNA gyrase
G6N84_RS22105	COG0142	geranyltranstransferase activity
G6N84_RS22110	COG1722	exodeoxyribonuclease VII activity
G6N84_RS22115	COG0037	tRNA processing
G6N84_RS22120	COG1785	Belongs to the alkaline phosphatase family
G6N84_RS22125	COG1301	dicarboxylic acid transport
G6N84_RS22140	COG0791	NLP P60 protein
G6N84_RS22145	COG0791	NLP P60 protein
G6N84_RS22150	COG1047	Peptidyl-prolyl cis-trans
G6N84_RS22155	COG2311	Membrane
G6N84_RS22160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6N84_RS22200	COG0489	protein tyrosine kinase activity
G6N84_RS22205	COG0717	Belongs to the dCTP deaminase family
G6N84_RS22225	COG0412	Dienelactone hydrolase
G6N84_RS22235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G6N84_RS22280	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N84_RS22285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G6N84_RS22290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G6N84_RS22295	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G6N84_RS22315	COG0101	tRNA pseudouridine synthase activity
G6N84_RS22320	COG0135	phosphoribosylanthranilate isomerase activity
G6N84_RS22345	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G6N84_RS22350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N84_RS22400	COG0149	triose-phosphate isomerase activity
G6N84_RS22415	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N84_RS22425	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N84_RS22430	COG0649	NAD binding
G6N84_RS22435	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
G6N84_RS22440	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G6N84_RS22445	COG1034	ATP synthesis coupled electron transport
G6N84_RS22450	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G6N84_RS22480	COG1007	ATP synthesis coupled electron transport
G6N84_RS22490	COG0779	Required for maturation of 30S ribosomal subunits
G6N84_RS22495	COG0195	Participates in both transcription termination and antitermination
G6N84_RS22515	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G6N84_RS22520	COG1185	polyribonucleotide nucleotidyltransferase activity
G6N84_RS22555	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G6N84_RS22565	COG2095	MarC family integral membrane protein
G6N84_RS22580	COG1611	Belongs to the LOG family
G6N84_RS22625	COG4969	Belongs to the N-Me-Phe pilin family
G6N84_RS22630	COG0556	nucleotide-excision repair
G6N84_RS22665	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G6N84_RS22735	COG0438	transferase activity, transferring glycosyl groups
G6N84_RS22740	COG0438	transferase activity, transferring glycosyl groups
G6N84_RS22750	COG0438	transferase activity, transferring glycosyl groups
G6N84_RS22795	COG3040	lipid binding
G6N84_RS22905	COG0552	protein localization to endoplasmic reticulum
G6N84_RS22915	COG3938	Belongs to the proline racemase family
G6N84_RS22920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6N84_RS22935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N84_RS22945	COG0006	proline dipeptidase activity
G6N84_RS22960	COG0531	amino acid
G6N84_RS22990	COG4206	TonB-dependent receptor
G6N84_RS23065	COG0746	molybdenum cofactor guanylyltransferase activity
G6N84_RS23090	COG1648	precorrin-2 dehydrogenase activity
G6N84_RS23090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6N84_RS23125	COG3039	Transposase
G6N84_RS23130	COG3039	Transposase
G6N84_RS23165	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G6N84_RS23205	COG1530	ribonuclease E activity
G6N84_RS23215	COG3064	Membrane
G6N84_RS23220	COG0428	transporter
G6N84_RS23225	COG0428	transporter
G6N84_RS23250	COG3039	Transposase
G6N84_RS23285	COG3039	Transposase
G6N84_RS23305	COG3039	Transposase
G6N84_RS23380	COG3501	Rhs element vgr protein
G6N84_RS23415	COG0631	protein serine/threonine phosphatase activity
G6N84_RS23420	COG0515	serine threonine protein kinase
G6N84_RS23450	COG1858	cytochrome C peroxidase