locus-tag	class	description
HAQ08_RS00020	COG1012	belongs to the aldehyde dehydrogenase family
HAQ08_RS00050	COG0697	spore germination
HAQ08_RS00055	COG1794	racemase activity, acting on amino acids and derivatives
HAQ08_RS00080	COG0671	phosphoesterase, PA-phosphatase related
HAQ08_RS00095	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HAQ08_RS00110	COG2183	response to ionizing radiation
HAQ08_RS00120	COG0723	plastoquinol--plastocyanin reductase activity
HAQ08_RS00120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAQ08_RS00135	COG3243	poly(R)-hydroxyalkanoic acid synthase
HAQ08_RS00145	COG1183	phosphatidylcholine synthase activity
HAQ08_RS00150	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ08_RS00200	COG0668	transmembrane transport
HAQ08_RS00220	COG1914	H( )-stimulated, divalent metal cation uptake system
HAQ08_RS00270	COG0583	DNA-binding transcription factor activity
HAQ08_RS00275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HAQ08_RS00295	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HAQ08_RS00315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HAQ08_RS00325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HAQ08_RS00330	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HAQ08_RS00340	COG0776	regulation of translation
HAQ08_RS00345	COG0539	negative regulation of cytoplasmic translation
HAQ08_RS00350	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HAQ08_RS00365	COG2957	Belongs to the agmatine deiminase family
HAQ08_RS00375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HAQ08_RS00400	COG0395	ABC-type sugar transport system, permease component
HAQ08_RS00405	COG1175	transmembrane transport
HAQ08_RS00445	COG2350	Protein conserved in bacteria
HAQ08_RS00450	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HAQ08_RS00455	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HAQ08_RS00460	COG1187	pseudouridine synthase activity
HAQ08_RS00485	COG0436	Aminotransferase
HAQ08_RS00550	COG0277	FAD linked oxidase domain protein
HAQ08_RS00555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HAQ08_RS00565	COG0531	amino acid
HAQ08_RS00570	COG0531	amino acid
HAQ08_RS00580	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HAQ08_RS00610	COG2201	protein-glutamate methylesterase activity
HAQ08_RS00655	COG0583	DNA-binding transcription factor activity
HAQ08_RS00665	COG3039	Transposase
HAQ08_RS00760	COG3039	Transposase
HAQ08_RS00765	COG3039	Transposase
HAQ08_RS00780	COG1278	Cold shock
HAQ08_RS00790	COG3328	transposase activity
HAQ08_RS00810	COG3039	Transposase
HAQ08_RS00820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAQ08_RS00840	COG0557	exoribonuclease II activity
HAQ08_RS00865	COG1960	acyl-CoA dehydrogenase activity
HAQ08_RS00870	COG2226	methyltransferase
HAQ08_RS00875	COG0646	methionine synthase
HAQ08_RS00875	COG1410	methionine synthase
HAQ08_RS00880	COG0646	methionine synthase
HAQ08_RS00880	COG1410	methionine synthase
HAQ08_RS00890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAQ08_RS00915	COG2900	Belongs to the SlyX family
HAQ08_RS00930	COG0386	Belongs to the glutathione peroxidase family
HAQ08_RS00940	COG1725	Transcriptional regulator
HAQ08_RS00945	COG1131	(ABC) transporter
HAQ08_RS01020	COG2850	peptidyl-arginine hydroxylation
HAQ08_RS01055	COG1132	(ABC) transporter
HAQ08_RS01070	COG0583	DNA-binding transcription factor activity
HAQ08_RS01085	COG1605	Chorismate mutase
HAQ08_RS01085	COG0287	Prephenate dehydrogenase
HAQ08_RS01090	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HAQ08_RS01095	COG0484	heat shock protein binding
HAQ08_RS01105	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HAQ08_RS01115	COG0497	DNA recombination
HAQ08_RS01125	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAQ08_RS01130	COG2914	Belongs to the UPF0125 (RnfH) family
HAQ08_RS01140	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HAQ08_RS01155	COG1960	acyl-CoA dehydrogenase activity
HAQ08_RS01165	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HAQ08_RS01210	COG2814	Major facilitator Superfamily
HAQ08_RS01215	COG1566	PFAM secretion protein HlyD family protein
HAQ08_RS01230	COG2207	Transcriptional regulator
HAQ08_RS01250	COG4774	siderophore transport
HAQ08_RS01260	COG0367	asparagine synthase
HAQ08_RS01275	COG1393	Belongs to the ArsC family
HAQ08_RS01335	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HAQ08_RS01350	COG0233	cytoplasmic translational termination
HAQ08_RS01360	COG0575	Belongs to the CDS family
HAQ08_RS01370	COG0750	zinc metalloprotease
HAQ08_RS01385	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HAQ08_RS01390	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HAQ08_RS01410	COG0825	malonyl-CoA metabolic process
HAQ08_RS01420	COG4771	TonB-dependent receptor
HAQ08_RS01425	COG1131	(ABC) transporter
HAQ08_RS01495	COG2895	sulfate adenylyltransferase (ATP) activity
HAQ08_RS01495	COG0529	Catalyzes the synthesis of activated sulfate
HAQ08_RS01530	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HAQ08_RS01545	COG2040	homocysteine
HAQ08_RS01550	COG0833	amino acid
HAQ08_RS01570	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAQ08_RS01570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAQ08_RS01580	COG2878	Part of a membrane complex involved in electron transport
HAQ08_RS01595	COG1595	DNA-templated transcription, initiation
HAQ08_RS01620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HAQ08_RS01635	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HAQ08_RS01640	COG0251	oxidation-reduction process
HAQ08_RS01650	COG0392	lysyltransferase activity
HAQ08_RS01650	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HAQ08_RS01685	COG2814	Major facilitator Superfamily
HAQ08_RS01690	COG1902	pentaerythritol trinitrate reductase activity
HAQ08_RS01700	COG2824	Alkylphosphonate utilization operon protein PhnA
HAQ08_RS01715	COG1047	Peptidyl-prolyl cis-trans
HAQ08_RS01750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HAQ08_RS01765	COG1451	nucleotide metabolic process
HAQ08_RS01785	COG0183	Belongs to the thiolase family
HAQ08_RS01815	COG1793	dna ligase
HAQ08_RS01815	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HAQ08_RS01825	COG1793	dna ligase
HAQ08_RS01830	COG1201	RNA secondary structure unwinding
HAQ08_RS01850	COG1278	Cold shock
HAQ08_RS01855	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HAQ08_RS01870	COG3046	protein related to deoxyribodipyrimidine photolyase
HAQ08_RS01875	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
HAQ08_RS01880	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HAQ08_RS01895	COG2954	triphosphatase activity
HAQ08_RS01910	COG1381	Involved in DNA repair and RecF pathway recombination
HAQ08_RS01940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAQ08_RS01955	COG1024	Enoyl-CoA hydratase
HAQ08_RS01955	COG1250	3-hydroxyacyl-CoA dehydrogenase
HAQ08_RS01975	COG1024	Enoyl-CoA hydratase
HAQ08_RS01980	COG1960	acyl-CoA dehydrogenase activity
HAQ08_RS02000	COG3867	Arabinogalactan endo-beta-1,4-galactanase
HAQ08_RS02040	COG3039	Transposase
HAQ08_RS02060	COG2353	YceI-like domain
HAQ08_RS02070	COG2353	YceI-like domain
HAQ08_RS02085	COG1760	l-serine dehydratase
HAQ08_RS02095	COG0626	cystathionine gamma-synthase activity
HAQ08_RS02100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAQ08_RS02105	COG0739	heme binding
HAQ08_RS02110	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HAQ08_RS02115	COG1272	protein, Hemolysin III
HAQ08_RS02140	COG0463	Glycosyl transferase, family 2
HAQ08_RS02150	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HAQ08_RS02160	COG4771	TonB-dependent receptor
HAQ08_RS02165	COG1309	transcriptional regulator
HAQ08_RS02175	COG1960	acyl-CoA dehydrogenase activity
HAQ08_RS02210	COG0509	glycine decarboxylation via glycine cleavage system
HAQ08_RS02225	COG0330	HflC and HflK could
HAQ08_RS02240	COG3956	TIGRFAM MazG family protein
HAQ08_RS02250	COG0494	nUDIX hydrolase
HAQ08_RS02260	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HAQ08_RS02265	COG0837	glucose binding
HAQ08_RS02280	COG1388	LysM domain
HAQ08_RS02280	COG3858	chitin binding
HAQ08_RS02290	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HAQ08_RS02300	COG1472	Belongs to the glycosyl hydrolase 3 family
HAQ08_RS02330	COG3039	Transposase
HAQ08_RS02345	COG3039	Transposase
HAQ08_RS02370	COG3537	Alpha-1,2-mannosidase
HAQ08_RS02420	COG3142	Participates in the control of copper homeostasis
HAQ08_RS02425	COG1446	asparaginase
HAQ08_RS02460	COG2198	Histidine kinase
HAQ08_RS02460	COG0784	Response regulator, receiver
HAQ08_RS02460	COG0643	Histidine kinase
HAQ08_RS02465	COG0840	transmembrane signaling receptor activity
HAQ08_RS02470	COG0835	chemotaxis
HAQ08_RS02485	COG0189	ligase activity
HAQ08_RS02495	COG1397	ADP-ribosylglycohydrolase
HAQ08_RS02505	COG1199	ATP-dependent helicase activity
HAQ08_RS02515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HAQ08_RS02520	COG1215	transferase activity, transferring glycosyl groups
HAQ08_RS02530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAQ08_RS02580	COG1643	Atp-dependent helicase
HAQ08_RS02585	COG0783	Belongs to the Dps family
HAQ08_RS02590	COG0514	ATP-dependent DNA helicase (RecQ)
HAQ08_RS02660	COG4695	Portal protein
HAQ08_RS02705	COG3179	chitinase
HAQ08_RS02880	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HAQ08_RS02910	COG0602	queuosine metabolic process
HAQ08_RS02920	COG2885	chlorophyll binding
HAQ08_RS02935	COG0848	biopolymer transport protein
HAQ08_RS02945	COG0824	Thioesterase
HAQ08_RS02950	COG2255	four-way junction helicase activity
HAQ08_RS02960	COG0632	four-way junction helicase activity
HAQ08_RS03070	COG3209	COG3209 Rhs family protein
HAQ08_RS03085	COG3209	COG3209 Rhs family protein
HAQ08_RS03085	COG3209	COG3209 Rhs family protein
HAQ08_RS03095	COG3501	Rhs element vgr protein
HAQ08_RS03105	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HAQ08_RS03110	COG1845	cytochrome c oxidase, subunit III
HAQ08_RS03115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HAQ08_RS03130	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HAQ08_RS03135	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HAQ08_RS03145	COG0196	riboflavin kinase activity
HAQ08_RS03150	COG0728	peptidoglycan biosynthetic process
HAQ08_RS03155	COG0268	Binds directly to 16S ribosomal RNA
HAQ08_RS03160	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HAQ08_RS03165	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HAQ08_RS03175	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HAQ08_RS03180	COG0824	Thioesterase
HAQ08_RS03195	COG1946	Acyl-CoA thioesterase
HAQ08_RS03205	COG1595	DNA-templated transcription, initiation
HAQ08_RS03260	COG1877	trehalose-phosphatase activity
HAQ08_RS03265	COG3387	PFAM Glycoside hydrolase 15-related
HAQ08_RS03290	COG0564	pseudouridine synthase activity
HAQ08_RS03295	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAQ08_RS03300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HAQ08_RS03300	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HAQ08_RS03315	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HAQ08_RS03320	COG0045	succinate-CoA ligase (ADP-forming) activity
HAQ08_RS03360	COG2194	sulfuric ester hydrolase activity
HAQ08_RS03365	COG4969	Belongs to the N-Me-Phe pilin family
HAQ08_RS03375	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HAQ08_RS03420	COG3039	Transposase
HAQ08_RS03450	COG3039	Transposase
HAQ08_RS03465	COG3039	Transposase
HAQ08_RS03510	COG1132	(ABC) transporter
HAQ08_RS03540	COG0745	RESPONSE REGULATOR receiver
HAQ08_RS03545	COG5002	protein histidine kinase activity
HAQ08_RS03545	COG5000	phosphorelay sensor kinase activity
HAQ08_RS03550	COG0475	glutathione-regulated potassium exporter activity
HAQ08_RS03560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HAQ08_RS03580	COG1187	pseudouridine synthase activity
HAQ08_RS03585	COG5002	protein histidine kinase activity
HAQ08_RS03585	COG5001	Diguanylate cyclase
HAQ08_RS03685	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ08_RS03700	COG0415	Belongs to the DNA photolyase family
HAQ08_RS03705	COG0305	Participates in initiation and elongation during chromosome replication
HAQ08_RS03715	COG0367	asparagine synthase
HAQ08_RS03730	COG1960	acyl-CoA dehydrogenase activity
HAQ08_RS03745	COG0084	hydrolase, TatD family'
HAQ08_RS03750	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HAQ08_RS03810	COG0735	belongs to the Fur family
HAQ08_RS03815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HAQ08_RS03845	COG3039	Transposase
HAQ08_RS03855	COG3039	Transposase
HAQ08_RS03880	COG3039	Transposase
HAQ08_RS03905	COG2205	protein histidine kinase activity
HAQ08_RS03920	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HAQ08_RS03930	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HAQ08_RS03945	COG2198	Histidine kinase
HAQ08_RS03945	COG0643	Histidine kinase
HAQ08_RS03950	COG0840	transmembrane signaling receptor activity
HAQ08_RS03955	COG0835	chemotaxis
HAQ08_RS03960	COG2202	Pas domain
HAQ08_RS03960	COG2199	diguanylate cyclase activity
HAQ08_RS03960	COG2200	EAL domain
HAQ08_RS03965	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HAQ08_RS03980	COG3590	peptidase
HAQ08_RS04000	COG1515	deoxyribonuclease V activity
HAQ08_RS04010	COG1741	Belongs to the pirin family
HAQ08_RS04040	COG3501	Rhs element vgr protein
HAQ08_RS04070	COG3501	Rhs element vgr protein
HAQ08_RS04090	COG3501	Rhs element vgr protein
HAQ08_RS04100	COG1741	Belongs to the pirin family
HAQ08_RS04105	COG1966	Carbon starvation protein
HAQ08_RS04110	COG2879	small protein
HAQ08_RS04145	COG2203	Gaf domain
HAQ08_RS04145	COG4251	negative regulation of phosphorylation
HAQ08_RS04145	COG3706	GGDEF domain
HAQ08_RS04145	COG5001	Diguanylate cyclase
HAQ08_RS04150	COG0629	single-stranded DNA binding
HAQ08_RS04155	COG0142	geranyltranstransferase activity
HAQ08_RS04180	COG0527	aspartate kinase activity
HAQ08_RS04190	COG0384	phenazine biosynthesis protein PhzF
HAQ08_RS04200	COG1764	response to oxidative stress
HAQ08_RS04215	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HAQ08_RS04220	COG1678	Uncharacterized ACR, COG1678
HAQ08_RS04230	COG0519	Catalyzes the synthesis of GMP from XMP
HAQ08_RS04260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HAQ08_RS04300	COG0693	protein deglycase activity
HAQ08_RS04320	COG1959	2 iron, 2 sulfur cluster binding
HAQ08_RS04325	COG0719	Fe-S assembly protein
HAQ08_RS04330	COG0396	ATPase activity
HAQ08_RS04335	COG0719	Fe-S assembly protein
HAQ08_RS04340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HAQ08_RS04350	COG2146	nitrite reductase [NAD(P)H] activity
HAQ08_RS04385	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HAQ08_RS04400	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HAQ08_RS04410	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
HAQ08_RS04415	COG0174	glutamine synthetase
HAQ08_RS04420	COG3328	transposase activity
HAQ08_RS04445	COG0326	Molecular chaperone. Has ATPase activity
HAQ08_RS04450	COG2207	Transcriptional regulator
HAQ08_RS04485	COG0657	acetylesterase activity
HAQ08_RS04485	COG2755	lipolytic protein G-D-S-L family
HAQ08_RS04510	COG0488	(ABC) transporter
HAQ08_RS04545	COG4651	solute:proton antiporter activity
HAQ08_RS04545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HAQ08_RS04560	COG4772	TonB-dependent receptor
HAQ08_RS04570	COG4264	IucA IucC family
HAQ08_RS04575	COG2814	Major facilitator Superfamily
HAQ08_RS04585	COG0019	diaminopimelate decarboxylase activity
HAQ08_RS04645	COG4206	TonB-dependent receptor
HAQ08_RS04680	COG0542	response to heat
HAQ08_RS04715	COG0534	Mate efflux family protein
HAQ08_RS04730	COG0336	Belongs to the RNA methyltransferase TrmD family
HAQ08_RS04735	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HAQ08_RS04740	COG0228	four-way junction DNA binding
HAQ08_RS04760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HAQ08_RS04770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HAQ08_RS04815	COG1555	photosystem II stabilization
HAQ08_RS04820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HAQ08_RS04835	COG3178	'Phosphotransferase
HAQ08_RS04840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HAQ08_RS04850	COG0628	permease
HAQ08_RS04860	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HAQ08_RS04875	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HAQ08_RS04895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAQ08_RS04900	COG0271	Belongs to the BolA IbaG family
HAQ08_RS04910	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HAQ08_RS04920	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HAQ08_RS04925	COG1137	ATPase activity
HAQ08_RS04940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HAQ08_RS04945	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HAQ08_RS04950	COG1660	Displays ATPase and GTPase activities
HAQ08_RS04965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HAQ08_RS04970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAQ08_RS04975	COG2239	Acts as a magnesium transporter
HAQ08_RS04985	COG1294	oxidase, subunit
HAQ08_RS04990	COG1271	oxidase subunit
HAQ08_RS05005	COG1113	amino acid transport
HAQ08_RS05020	COG2197	response regulator
HAQ08_RS05025	COG0531	amino acid
HAQ08_RS05090	COG0754	glutathionylspermidine amidase activity
HAQ08_RS05115	COG1842	Phage shock protein A
HAQ08_RS05130	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HAQ08_RS05135	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HAQ08_RS05145	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HAQ08_RS05175	COG2201	protein-glutamate methylesterase activity
HAQ08_RS05285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HAQ08_RS05290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HAQ08_RS05315	COG3039	Transposase
HAQ08_RS05330	COG0745	RESPONSE REGULATOR receiver
HAQ08_RS05335	COG2205	protein histidine kinase activity
HAQ08_RS05355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HAQ08_RS05385	COG3453	Protein conserved in bacteria
HAQ08_RS05385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAQ08_RS05390	COG0725	ABC transporter, periplasmic molybdate-binding protein
HAQ08_RS05395	COG4149	molybdate abc transporter
HAQ08_RS05400	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HAQ08_RS05420	COG0642	Histidine kinase
HAQ08_RS05425	COG0745	RESPONSE REGULATOR receiver
HAQ08_RS05435	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ08_RS05470	COG1376	ErfK ybiS ycfS ynhG family protein
HAQ08_RS05475	COG0739	heme binding
HAQ08_RS05485	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HAQ08_RS05490	COG1301	dicarboxylic acid transport
HAQ08_RS05510	COG2304	oxidoreductase activity
HAQ08_RS05530	COG0714	Associated with various cellular activities
HAQ08_RS05580	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HAQ08_RS05605	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HAQ08_RS05615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAQ08_RS05640	COG1561	YicC-like family, N-terminal region
HAQ08_RS05645	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HAQ08_RS05660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HAQ08_RS05700	COG0006	proline dipeptidase activity
HAQ08_RS05725	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HAQ08_RS05735	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HAQ08_RS05745	COG2912	Transglutaminase-like superfamily
HAQ08_RS05750	COG1773	rubredoxin
HAQ08_RS05755	COG0352	thiamine-phosphate diphosphorylase activity
HAQ08_RS05780	COG0280	phosphate acetyltransferase
HAQ08_RS05780	COG0281	malic enzyme
HAQ08_RS05800	COG4191	Histidine kinase
HAQ08_RS05815	COG0583	DNA-binding transcription factor activity
HAQ08_RS05830	COG2197	response regulator
HAQ08_RS05840	COG0642	Histidine kinase
HAQ08_RS05855	COG2851	Citrate transporter
HAQ08_RS05860	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ08_RS05865	COG1609	Transcriptional regulator
HAQ08_RS05875	COG2211	Major facilitator Superfamily
HAQ08_RS05925	COG0726	polysaccharide deacetylase
HAQ08_RS05930	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HAQ08_RS05955	COG3039	Transposase
HAQ08_RS06005	COG0242	peptide deformylase activity
HAQ08_RS06025	COG0714	Associated with various cellular activities
HAQ08_RS06045	COG0537	adenosine 5'-monophosphoramidase activity
HAQ08_RS06075	COG0314	molybdopterin synthase activity
HAQ08_RS06080	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HAQ08_RS06085	COG0315	cyclic pyranopterin monophosphate synthase activity
HAQ08_RS06095	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HAQ08_RS06100	COG1234	tRNA 3'-trailer cleavage
HAQ08_RS06105	COG3642	lipopolysaccharide core region biosynthetic process
HAQ08_RS06110	COG0859	PFAM glycosyl transferase family 9
HAQ08_RS06120	COG0582	viral genome integration into host DNA
HAQ08_RS06180	COG3501	Rhs element vgr protein
HAQ08_RS06205	COG0631	protein serine/threonine phosphatase activity
HAQ08_RS06220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HAQ08_RS06245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HAQ08_RS06285	COG0544	peptidyl-prolyl cis-trans isomerase activity
HAQ08_RS06335	COG0473	3-isopropylmalate dehydrogenase activity
HAQ08_RS06360	COG0584	glycerophosphoryl diester phosphodiesterase
HAQ08_RS06380	COG3039	Transposase
HAQ08_RS06510	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HAQ08_RS06535	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAQ08_RS06545	COG0625	glutathione transferase activity
HAQ08_RS06560	COG3781	membrane
HAQ08_RS06570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HAQ08_RS06600	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HAQ08_RS06610	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HAQ08_RS06620	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HAQ08_RS06645	COG3710	Transcriptional regulator
HAQ08_RS06650	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HAQ08_RS06660	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HAQ08_RS06695	COG0066	3-isopropylmalate dehydratase activity
HAQ08_RS06700	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAQ08_RS06730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HAQ08_RS06735	COG1538	Outer membrane efflux protein
HAQ08_RS06740	COG1519	Transferase
HAQ08_RS06745	COG1560	Kdo2-lipid A biosynthetic process
HAQ08_RS06790	COG0308	aminopeptidase N
HAQ08_RS06805	COG0330	HflC and HflK could
HAQ08_RS06810	COG0330	HflC and HflK could
HAQ08_RS06830	COG0678	peroxiredoxin activity
HAQ08_RS06840	COG2826	transposase and inactivated derivatives, IS30 family
HAQ08_RS06920	COG3829	transcription factor binding
HAQ08_RS06955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HAQ08_RS06960	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HAQ08_RS06970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAQ08_RS06975	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ08_RS07000	COG1399	metal-binding, possibly nucleic acid-binding protein
HAQ08_RS07045	COG1518	maintenance of DNA repeat elements
HAQ08_RS07050	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HAQ08_RS07095	COG2188	Transcriptional regulator
HAQ08_RS07110	COG1450	Type ii and iii secretion system protein
HAQ08_RS07125	COG3166	PFAM Fimbrial assembly family protein
HAQ08_RS07130	COG3156	type II secretion system protein K
HAQ08_RS07135	COG4795	General secretion pathway protein
HAQ08_RS07140	COG2165	general secretion pathway protein
HAQ08_RS07145	COG4970	Tfp pilus assembly protein FimT
HAQ08_RS07150	COG2165	general secretion pathway protein
HAQ08_RS07155	COG1459	type II secretion system
HAQ08_RS07165	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HAQ08_RS07170	COG1404	Belongs to the peptidase S8 family
HAQ08_RS07175	COG1404	Belongs to the peptidase S8 family
HAQ08_RS07180	COG1404	Belongs to the peptidase S8 family
HAQ08_RS07190	COG5295	Hep Hag repeat protein
HAQ08_RS07195	COG0047	phosphoribosylformylglycinamidine synthase activity
HAQ08_RS07195	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAQ08_RS07200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HAQ08_RS07205	COG4974	Belongs to the 'phage' integrase family
HAQ08_RS07220	COG0795	lipopolysaccharide-transporting ATPase activity
HAQ08_RS07230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HAQ08_RS07245	COG0525	valine-tRNA ligase activity
HAQ08_RS07300	COG3039	Transposase
HAQ08_RS07330	COG1183	phosphatidylcholine synthase activity
HAQ08_RS07340	COG0442	prolyl-tRNA aminoacylation
HAQ08_RS07355	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HAQ08_RS07360	COG1127	ABC transporter
HAQ08_RS07365	COG3218	ABC-type transport auxiliary lipoprotein component
HAQ08_RS07365	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HAQ08_RS07400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAQ08_RS07405	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HAQ08_RS07405	COG0662	Cupin 2, conserved barrel domain protein
HAQ08_RS07430	COG2086	electron transfer activity
HAQ08_RS07455	COG3328	transposase activity
HAQ08_RS07495	COG0626	cystathionine gamma-synthase activity
HAQ08_RS07540	COG0513	Belongs to the DEAD box helicase family
HAQ08_RS07545	COG0720	synthase
HAQ08_RS07555	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HAQ08_RS07560	COG1956	GAF domain-containing protein
HAQ08_RS07595	COG0339	signal peptide processing
HAQ08_RS07640	COG3039	Transposase
HAQ08_RS07660	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HAQ08_RS07665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAQ08_RS07715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HAQ08_RS07720	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HAQ08_RS07725	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HAQ08_RS07730	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HAQ08_RS07740	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HAQ08_RS07750	COG0356	it plays a direct role in the translocation of protons across the membrane
HAQ08_RS07770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HAQ08_RS07780	COG0508	dehydrogenase complex catalyzes the overall conversion of
HAQ08_RS07810	COG2011	ABC-type metal ion transport system permease component
HAQ08_RS07820	COG0697	spore germination
HAQ08_RS07855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HAQ08_RS07860	COG1187	pseudouridine synthase activity
HAQ08_RS07865	COG2813	Specifically methylates the guanine in position
HAQ08_RS07895	COG2205	protein histidine kinase activity
HAQ08_RS07895	COG2202	Pas domain
HAQ08_RS07920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAQ08_RS07970	COG0745	RESPONSE REGULATOR receiver
HAQ08_RS07985	COG1404	Belongs to the peptidase S8 family
HAQ08_RS08000	COG0842	Transport permease protein
HAQ08_RS08005	COG1131	(ABC) transporter
HAQ08_RS08010	COG0025	NhaP-type Na H and K H
HAQ08_RS08030	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HAQ08_RS08040	COG1573	uracil-dna glycosylase
HAQ08_RS08050	COG3384	dioxygenase
HAQ08_RS08065	COG0667	Aldo Keto reductase
HAQ08_RS08075	COG3590	peptidase
HAQ08_RS08095	COG0531	amino acid
HAQ08_RS08120	COG2972	Histidine kinase
HAQ08_RS08175	COG1271	oxidase subunit
HAQ08_RS08180	COG1294	oxidase, subunit
HAQ08_RS08405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAQ08_RS08415	COG1560	Kdo2-lipid A biosynthetic process
HAQ08_RS08465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HAQ08_RS08465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAQ08_RS08470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HAQ08_RS08475	COG0242	peptide deformylase activity
HAQ08_RS08480	COG1652	LysM domain
HAQ08_RS08485	COG0758	DNA mediated transformation
HAQ08_RS08490	COG2922	Belongs to the Smg family
HAQ08_RS08505	COG1754	DNA topoisomerase type I activity
HAQ08_RS08505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HAQ08_RS08510	COG0009	L-threonylcarbamoyladenylate synthase
HAQ08_RS08525	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ08_RS08535	COG0616	signal peptide processing
HAQ08_RS08540	COG0534	Mate efflux family protein
HAQ08_RS08560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HAQ08_RS08595	COG1324	tolerance protein
HAQ08_RS08605	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HAQ08_RS08610	COG0511	ligase activity, forming carbon-carbon bonds
HAQ08_RS08620	COG0439	Biotin carboxylase
HAQ08_RS08665	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HAQ08_RS08685	COG2267	carboxylic ester hydrolase activity
HAQ08_RS08695	COG2267	carboxylic ester hydrolase activity
HAQ08_RS08710	COG0419	ATPase involved in DNA repair
HAQ08_RS08720	COG0151	Belongs to the GarS family
HAQ08_RS08725	COG0577	efflux transmembrane transporter activity
HAQ08_RS08725	COG1136	(ABC) transporter
HAQ08_RS08735	COG1289	transmembrane transporter activity
HAQ08_RS08750	COG2814	Major facilitator Superfamily
HAQ08_RS08775	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HAQ08_RS08810	COG0745	RESPONSE REGULATOR receiver
HAQ08_RS08855	COG0739	heme binding
HAQ08_RS08870	COG2211	Major facilitator Superfamily
HAQ08_RS08875	COG0708	Exodeoxyribonuclease III
HAQ08_RS08890	COG1192	Involved in chromosome partitioning
HAQ08_RS08895	COG1475	DNA binding
HAQ08_RS08910	COG0463	Glycosyl transferase, family 2
HAQ08_RS08930	COG0756	dUTP diphosphatase activity
HAQ08_RS08935	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HAQ08_RS08940	COG2003	Belongs to the UPF0758 family
HAQ08_RS08945	COG0018	arginyl-trna synthetase
HAQ08_RS08960	COG4221	oxidoreductase activity
HAQ08_RS08985	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HAQ08_RS08990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAQ08_RS09005	COG3485	protocatechuate 3,4-dioxygenase
HAQ08_RS09010	COG3485	protocatechuate 3,4-dioxygenase
HAQ08_RS09045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAQ08_RS09050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAQ08_RS09060	COG1042	CoA-binding domain protein
HAQ08_RS09060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HAQ08_RS09060	COG0045	succinate-CoA ligase (ADP-forming) activity
HAQ08_RS09075	COG2239	Acts as a magnesium transporter
HAQ08_RS09090	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HAQ08_RS09095	COG3387	PFAM Glycoside hydrolase 15-related
HAQ08_RS09110	COG3100	YcgL domain-containing protein
HAQ08_RS09115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HAQ08_RS09125	COG0463	Glycosyl transferase, family 2
HAQ08_RS09140	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ08_RS09150	COG0156	8-amino-7-oxononanoate synthase activity
HAQ08_RS09155	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HAQ08_RS09160	COG1040	competence protein
HAQ08_RS09165	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HAQ08_RS09175	COG0628	permease
HAQ08_RS09185	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HAQ08_RS09195	COG1595	DNA-templated transcription, initiation
HAQ08_RS09200	COG0753	catalase activity
HAQ08_RS09245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAQ08_RS09250	COG0180	Tryptophanyl-tRNA synthetase
HAQ08_RS09255	COG3237	CsbD-like
HAQ08_RS09290	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HAQ08_RS09305	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HAQ08_RS09310	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HAQ08_RS09310	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HAQ08_RS09335	COG2205	protein histidine kinase activity
HAQ08_RS09340	COG0745	RESPONSE REGULATOR receiver
HAQ08_RS09350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAQ08_RS09370	COG1566	PFAM secretion protein HlyD family protein
HAQ08_RS09390	COG1199	ATP-dependent helicase activity
HAQ08_RS09430	COG0583	DNA-binding transcription factor activity
HAQ08_RS09475	COG0625	glutathione transferase activity
HAQ08_RS09515	COG4555	ABC transporter
HAQ08_RS09525	COG1476	TRANSCRIPTIONal
HAQ08_RS09545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HAQ08_RS09550	COG1131	(ABC) transporter
HAQ08_RS09555	COG0842	Transport permease protein
HAQ08_RS09565	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HAQ08_RS09650	COG1181	Belongs to the D-alanine--D-alanine ligase family
HAQ08_RS09660	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HAQ08_RS09670	COG0564	pseudouridine synthase activity
HAQ08_RS09700	COG0339	signal peptide processing
HAQ08_RS09730	COG3254	rhamnose metabolic process
HAQ08_RS09735	COG0738	Major facilitator superfamily
HAQ08_RS09740	COG1414	Transcriptional regulator
HAQ08_RS09750	COG2205	protein histidine kinase activity
HAQ08_RS09760	COG3459	Glycosyltransferase 36 associated
HAQ08_RS09765	COG2211	Major facilitator Superfamily
HAQ08_RS09770	COG3265	gluconokinase activity
HAQ08_RS09780	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAQ08_RS09860	COG1127	ABC transporter
HAQ08_RS09865	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HAQ08_RS09870	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HAQ08_RS09885	COG2853	Lipoprotein
HAQ08_RS09905	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HAQ08_RS09970	COG0676	glucose-6-phosphate 1-epimerase activity
HAQ08_RS09995	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HAQ08_RS10005	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HAQ08_RS10015	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HAQ08_RS10020	COG1064	alcohol dehydrogenase
HAQ08_RS10065	COG1522	sequence-specific DNA binding
HAQ08_RS10070	COG3186	Phenylalanine-4-hydroxylase
HAQ08_RS10110	COG2937	Belongs to the GPAT DAPAT family
HAQ08_RS10145	COG0284	orotidine-5'-phosphate decarboxylase activity
HAQ08_RS10150	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HAQ08_RS10155	COG3132	Protein of unknown function, DUF480
HAQ08_RS10170	COG0210	DNA helicase
HAQ08_RS10185	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HAQ08_RS10210	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ08_RS10285	COG3501	Rhs element vgr protein
HAQ08_RS10295	COG1166	arginine decarboxylase activity
HAQ08_RS10300	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HAQ08_RS10340	COG0606	chelatase, subunit chli
HAQ08_RS10385	COG0366	Alpha amylase catalytic
HAQ08_RS10390	COG0366	Alpha amylase catalytic
HAQ08_RS10420	COG1609	Transcriptional regulator
HAQ08_RS10460	COG0493	'glutamate synthase
HAQ08_RS10465	COG0070	glutamate synthase
HAQ08_RS10465	COG0069	glutamate synthase activity
HAQ08_RS10465	COG0067	glutamate synthase
HAQ08_RS10525	COG1111	helicase
HAQ08_RS10525	COG1205	dead DEAH box helicase
HAQ08_RS10530	COG1272	protein, Hemolysin III
HAQ08_RS10570	COG1136	(ABC) transporter
HAQ08_RS10610	COG3039	Transposase
HAQ08_RS10620	COG3039	Transposase
HAQ08_RS10630	COG1136	(ABC) transporter
HAQ08_RS10675	COG3039	Transposase
HAQ08_RS10680	COG0513	Belongs to the DEAD box helicase family
HAQ08_RS10780	COG1858	cytochrome C peroxidase
HAQ08_RS10795	COG0702	epimerase
HAQ08_RS10820	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HAQ08_RS10845	COG2354	Protein conserved in bacteria
HAQ08_RS10850	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HAQ08_RS10865	COG3264	Mechanosensitive ion channel
HAQ08_RS10865	COG1511	domain protein
HAQ08_RS10940	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HAQ08_RS11015	COG3039	Transposase
HAQ08_RS11025	COG3039	Transposase
HAQ08_RS11065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAQ08_RS11075	COG0642	Histidine kinase
HAQ08_RS11085	COG1090	epimerase
HAQ08_RS11095	COG3039	Transposase
HAQ08_RS11120	COG2826	transposase and inactivated derivatives, IS30 family
HAQ08_RS11205	COG3039	Transposase
HAQ08_RS11215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAQ08_RS11225	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HAQ08_RS11240	COG1755	Isoprenylcysteine carboxyl methyltransferase
HAQ08_RS11245	COG1304	FMN binding
HAQ08_RS11250	COG3039	Transposase
HAQ08_RS11265	COG4772	TonB-dependent receptor
HAQ08_RS11275	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HAQ08_RS11285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAQ08_RS11295	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HAQ08_RS11325	COG0501	Belongs to the peptidase M48B family
HAQ08_RS11335	COG0187	DNA topoisomerase II activity
HAQ08_RS11350	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HAQ08_RS11370	COG0726	polysaccharide deacetylase
HAQ08_RS11380	COG0671	phosphoesterase, PA-phosphatase related
HAQ08_RS11390	COG0584	glycerophosphoryl diester phosphodiesterase
HAQ08_RS11400	COG0861	Integral membrane protein TerC family
HAQ08_RS11405	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HAQ08_RS11420	COG2271	Major facilitator Superfamily
HAQ08_RS11425	COG1929	Belongs to the glycerate kinase type-1 family
HAQ08_RS11515	COG0477	Major facilitator Superfamily
HAQ08_RS11535	COG0302	gtp cyclohydrolase
HAQ08_RS11540	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAQ08_RS11585	COG2234	aminopeptidase activity
HAQ08_RS11595	COG4942	peptidase
HAQ08_RS11600	COG0793	Belongs to the peptidase S41A family
HAQ08_RS11650	COG0386	Belongs to the glutathione peroxidase family
HAQ08_RS11660	COG1322	Protein conserved in bacteria
HAQ08_RS11675	COG0531	amino acid
HAQ08_RS11690	COG0210	DNA helicase
HAQ08_RS11705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAQ08_RS11710	COG0583	DNA-binding transcription factor activity
HAQ08_RS11715	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HAQ08_RS11735	COG2159	amidohydrolase
HAQ08_RS11760	COG0357	Ribosomal RNA small subunit methyltransferase G
HAQ08_RS11765	COG3540	Alkaline phosphatase
HAQ08_RS11775	COG2091	lysine biosynthetic process via aminoadipic acid
HAQ08_RS11790	COG0708	Exodeoxyribonuclease III
HAQ08_RS11805	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAQ08_RS11810	COG3162	membrane
HAQ08_RS11850	COG3507	Belongs to the glycosyl hydrolase 43 family
HAQ08_RS11870	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ08_RS11875	COG0179	Fumarylacetoacetate (FAA) hydrolase
HAQ08_RS11880	COG4948	Mandelate Racemase Muconate Lactonizing
HAQ08_RS11885	COG4807	Protein conserved in bacteria
HAQ08_RS11890	COG1643	Atp-dependent helicase
HAQ08_RS11905	COG1187	pseudouridine synthase activity
HAQ08_RS11915	COG0667	Aldo Keto reductase
HAQ08_RS11920	COG2130	NADP-dependent
HAQ08_RS11960	COG1752	Esterase of the alpha-beta hydrolase superfamily
HAQ08_RS11970	COG1119	ATPase activity
HAQ08_RS11985	COG1125	glycine betaine transport
HAQ08_RS11985	COG0517	IMP dehydrogenase activity
HAQ08_RS12000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HAQ08_RS12005	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HAQ08_RS12010	COG3550	peptidyl-serine autophosphorylation
HAQ08_RS12015	COG1396	sequence-specific DNA binding
HAQ08_RS12035	COG0489	protein tyrosine kinase activity
HAQ08_RS12040	COG2062	phosphohistidine phosphatase, SixA
HAQ08_RS12050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAQ08_RS12095	COG1968	undecaprenyl-diphosphatase activity
HAQ08_RS12100	COG0174	glutamine synthetase
HAQ08_RS12105	COG0347	Belongs to the P(II) protein family
HAQ08_RS12110	COG0004	ammonium transporteR
HAQ08_RS12115	COG3852	Histidine kinase
HAQ08_RS12120	COG2204	response regulator
HAQ08_RS12125	COG2032	superoxide dismutase activity
HAQ08_RS12130	COG2032	superoxide dismutase activity
HAQ08_RS12170	COG1196	nuclear chromosome segregation
HAQ08_RS12180	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HAQ08_RS12185	COG1074	ATP-dependent DNA helicase activity
HAQ08_RS12190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HAQ08_RS12195	COG3549	Plasmid maintenance system killer
HAQ08_RS12275	COG1764	response to oxidative stress
HAQ08_RS12280	COG1846	Transcriptional regulator
HAQ08_RS12325	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HAQ08_RS12370	COG2211	Major facilitator Superfamily
HAQ08_RS12390	COG3693	PFAM glycoside hydrolase, family 10
HAQ08_RS12415	COG0246	Mannitol dehydrogenase
HAQ08_RS12420	COG1472	Belongs to the glycosyl hydrolase 3 family
HAQ08_RS12430	COG4948	Mandelate Racemase Muconate Lactonizing
HAQ08_RS12440	COG3661	Belongs to the glycosyl hydrolase 67 family
HAQ08_RS12460	COG2974	May be involved in recombination
HAQ08_RS12485	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HAQ08_RS12495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HAQ08_RS12505	COG0805	protein transport
HAQ08_RS12515	COG0519	Catalyzes the synthesis of GMP from XMP
HAQ08_RS12515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HAQ08_RS12530	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HAQ08_RS12535	COG0752	glycyl-tRNA synthetase alpha subunit
HAQ08_RS12545	COG0457	Tetratricopeptide repeat
HAQ08_RS12550	COG4771	TonB-dependent receptor
HAQ08_RS12565	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HAQ08_RS12575	COG0697	spore germination
HAQ08_RS12585	COG0523	cobalamin synthesis protein
HAQ08_RS12640	COG1960	acyl-CoA dehydrogenase activity
HAQ08_RS12645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HAQ08_RS12650	COG4770	biotin carboxylase activity
HAQ08_RS12695	COG2072	flavoprotein involved in K transport
HAQ08_RS12715	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HAQ08_RS12760	COG0084	hydrolase, TatD family'
HAQ08_RS12775	COG0583	DNA-binding transcription factor activity
HAQ08_RS12780	COG2814	Major facilitator Superfamily
HAQ08_RS12790	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HAQ08_RS12795	COG1902	pentaerythritol trinitrate reductase activity
HAQ08_RS12825	COG0745	RESPONSE REGULATOR receiver
HAQ08_RS12845	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HAQ08_RS12850	COG0583	DNA-binding transcription factor activity
HAQ08_RS12880	COG0702	epimerase
HAQ08_RS12885	COG1733	regulation of RNA biosynthetic process
HAQ08_RS12935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAQ08_RS12950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HAQ08_RS12985	COG2911	Protein conserved in bacteria
HAQ08_RS12990	COG0729	surface antigen
HAQ08_RS13005	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HAQ08_RS13010	COG3118	belongs to the thioredoxin family
HAQ08_RS13020	COG2884	Cell division ATP-binding protein ftsE
HAQ08_RS13025	COG2177	Part of the ABC transporter FtsEX involved in
HAQ08_RS13030	COG2201	protein-glutamate methylesterase activity
HAQ08_RS13035	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HAQ08_RS13040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAQ08_RS13050	COG1252	NADH dehydrogenase
HAQ08_RS13075	COG0459	protein refolding
HAQ08_RS13085	COG4771	TonB-dependent receptor
HAQ08_RS13100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HAQ08_RS13140	COG3386	PFAM SMP-30 Gluconolaconase
HAQ08_RS13155	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HAQ08_RS13185	COG2353	YceI-like domain
HAQ08_RS13230	COG2201	protein-glutamate methylesterase activity
HAQ08_RS13240	COG3039	Transposase
HAQ08_RS13260	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HAQ08_RS13320	COG0408	coproporphyrinogen oxidase activity
HAQ08_RS13330	COG3039	Transposase
HAQ08_RS13350	COG0129	dihydroxy-acid dehydratase activity
HAQ08_RS13360	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HAQ08_RS13410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HAQ08_RS13415	COG0318	PFAM AMP-dependent synthetase and ligase
HAQ08_RS13420	COG0727	PFAM Uncharacterised protein family (UPF0153)
HAQ08_RS13425	COG0596	Alpha beta hydrolase
HAQ08_RS13440	COG3177	Filamentation induced by cAMP protein fic
HAQ08_RS13445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAQ08_RS13460	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HAQ08_RS13485	COG4191	Histidine kinase
HAQ08_RS13490	COG0028	Belongs to the TPP enzyme family
HAQ08_RS13505	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HAQ08_RS13510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HAQ08_RS13545	COG5383	Protein conserved in bacteria
HAQ08_RS13560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAQ08_RS13565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAQ08_RS13570	COG1473	amidohydrolase
HAQ08_RS13580	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HAQ08_RS13580	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HAQ08_RS13600	COG3039	Transposase
HAQ08_RS13675	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HAQ08_RS13690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HAQ08_RS13695	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HAQ08_RS13705	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
HAQ08_RS13710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HAQ08_RS13715	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HAQ08_RS13765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HAQ08_RS13780	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HAQ08_RS13845	COG0358	DNA primase activity
HAQ08_RS13850	COG1295	ribonuclease BN
HAQ08_RS13860	COG1610	YqeY-like protein
HAQ08_RS13870	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HAQ08_RS13875	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HAQ08_RS13915	COG2133	pyrroloquinoline quinone binding
HAQ08_RS13920	COG4682	membrane
HAQ08_RS13945	COG0531	amino acid
HAQ08_RS13975	COG4948	Mandelate Racemase Muconate Lactonizing
HAQ08_RS13985	COG3023	N-Acetylmuramoyl-L-alanine amidase
HAQ08_RS13990	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HAQ08_RS14060	COG0183	Belongs to the thiolase family
HAQ08_RS14095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HAQ08_RS14105	COG3483	tryptophan 2,3-dioxygenase activity
HAQ08_RS14110	COG3104	oligopeptide transport
HAQ08_RS14140	COG1320	monovalent cation:proton antiporter activity
HAQ08_RS14145	COG2212	antiporter activity
HAQ08_RS14155	COG0651	ATP synthesis coupled electron transport
HAQ08_RS14160	COG1006	Multisubunit Na H antiporter MnhC subunit
HAQ08_RS14165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HAQ08_RS14165	COG2111	Na H antiporter
HAQ08_RS14205	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HAQ08_RS14215	COG0456	acetyltransferase
HAQ08_RS14245	COG4221	oxidoreductase activity
HAQ08_RS14300	COG0697	spore germination
HAQ08_RS14305	COG4305	rare lipoprotein A
HAQ08_RS14310	COG5297	Belongs to the glycosyl hydrolase family 6
HAQ08_RS14320	COG1113	amino acid transport
HAQ08_RS14330	COG0598	Magnesium transport protein CorA
HAQ08_RS14400	COG5297	Belongs to the glycosyl hydrolase family 6
HAQ08_RS14400	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HAQ08_RS14405	COG0659	secondary active sulfate transmembrane transporter activity
HAQ08_RS14440	COG3275	phosphorelay sensor kinase activity
HAQ08_RS14475	COG1505	serine-type exopeptidase activity
HAQ08_RS14520	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HAQ08_RS14550	COG0308	aminopeptidase N
HAQ08_RS14555	COG2199	diguanylate cyclase activity
HAQ08_RS14605	COG3039	Transposase
HAQ08_RS14610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAQ08_RS14615	COG1077	Cell shape determining protein MreB Mrl
HAQ08_RS14620	COG1792	Involved in formation and maintenance of cell shape
HAQ08_RS14635	COG0772	Belongs to the SEDS family
HAQ08_RS14660	COG3501	Rhs element vgr protein
HAQ08_RS14700	COG2951	lytic endotransglycosylase activity
HAQ08_RS14705	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HAQ08_RS14710	COG1686	Belongs to the peptidase S11 family
HAQ08_RS14725	COG2921	Belongs to the UPF0250 family
HAQ08_RS14765	COG1051	belongs to the nudix hydrolase family
HAQ08_RS14765	COG1056	cytidyltransferase-related domain
HAQ08_RS14800	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HAQ08_RS14805	COG0673	inositol 2-dehydrogenase activity
HAQ08_RS14810	COG2823	Periplasmic or secreted lipoprotein
HAQ08_RS14815	COG4251	negative regulation of phosphorylation
HAQ08_RS14820	COG0784	Response regulator, receiver
HAQ08_RS14825	COG4191	Histidine kinase
HAQ08_RS14830	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HAQ08_RS14880	COG3250	beta-galactosidase activity
HAQ08_RS14895	COG2188	Transcriptional regulator
HAQ08_RS14905	COG1609	Transcriptional regulator
HAQ08_RS14910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HAQ08_RS14915	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HAQ08_RS14930	COG1215	transferase activity, transferring glycosyl groups
HAQ08_RS14935	COG1649	PFAM Uncharacterised BCR, COG1649
HAQ08_RS14935	COG0726	polysaccharide deacetylase
HAQ08_RS14970	COG3039	Transposase
HAQ08_RS15025	COG3039	Transposase
HAQ08_RS15045	COG3039	Transposase
HAQ08_RS15080	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HAQ08_RS15100	COG2205	protein histidine kinase activity
HAQ08_RS15135	COG2205	protein histidine kinase activity
HAQ08_RS15140	COG0745	RESPONSE REGULATOR receiver
HAQ08_RS15185	COG0488	(ABC) transporter
HAQ08_RS15205	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HAQ08_RS15225	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HAQ08_RS15225	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HAQ08_RS15245	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HAQ08_RS15250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAQ08_RS15255	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HAQ08_RS15275	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HAQ08_RS15280	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HAQ08_RS15290	COG2205	protein histidine kinase activity
HAQ08_RS15295	COG0745	RESPONSE REGULATOR receiver
HAQ08_RS15300	COG0277	FAD linked oxidase domain protein
HAQ08_RS15305	COG1988	membrane-bound metal-dependent
HAQ08_RS15310	COG0792	nuclease activity
HAQ08_RS15355	COG3116	cell division
HAQ08_RS15370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HAQ08_RS15390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HAQ08_RS15395	COG1181	Belongs to the D-alanine--D-alanine ligase family
HAQ08_RS15400	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HAQ08_RS15415	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HAQ08_RS15425	COG1388	LysM domain
HAQ08_RS15425	COG4942	peptidase
HAQ08_RS15440	COG0494	nUDIX hydrolase
HAQ08_RS15460	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HAQ08_RS15470	COG3321	synthase
HAQ08_RS15470	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ08_RS15470	COG0604	alcohol dehydrogenase
HAQ08_RS15515	COG2226	methyltransferase
HAQ08_RS15520	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HAQ08_RS15570	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HAQ08_RS15585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAQ08_RS15595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAQ08_RS15600	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HAQ08_RS15610	COG0667	Aldo Keto reductase
HAQ08_RS15665	COG2175	clavaminate synthase activity
HAQ08_RS15675	COG4181	ATPase activity
HAQ08_RS15690	COG0642	Histidine kinase
HAQ08_RS15715	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HAQ08_RS15735	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HAQ08_RS15760	COG2967	ApaG domain
HAQ08_RS15765	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HAQ08_RS15775	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HAQ08_RS15790	COG0123	including yeast histone deacetylase and acetoin utilization protein
HAQ08_RS15795	COG2096	Adenosyltransferase
HAQ08_RS15805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HAQ08_RS15810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HAQ08_RS15850	COG0583	DNA-binding transcription factor activity
HAQ08_RS15855	COG0318	PFAM AMP-dependent synthetase and ligase
HAQ08_RS15865	COG1024	Enoyl-CoA hydratase
HAQ08_RS16005	COG1902	pentaerythritol trinitrate reductase activity
HAQ08_RS16005	COG0446	pyridine nucleotide-disulphide oxidoreductase
HAQ08_RS16010	COG0604	alcohol dehydrogenase
HAQ08_RS16035	COG0156	8-amino-7-oxononanoate synthase activity
HAQ08_RS16040	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HAQ08_RS16045	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HAQ08_RS16050	COG4208	sulfate ABC transporter
HAQ08_RS16055	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HAQ08_RS16085	COG0588	phosphoglycerate mutase activity
HAQ08_RS16095	COG0285	dihydrofolate synthase activity
HAQ08_RS16115	COG2833	Protein of unknown function (DUF455)
HAQ08_RS16135	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HAQ08_RS16140	COG0671	phosphoesterase, PA-phosphatase related
HAQ08_RS16145	COG0438	transferase activity, transferring glycosyl groups
HAQ08_RS16155	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HAQ08_RS16170	COG4783	chaperone-mediated protein folding
HAQ08_RS16205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAQ08_RS16235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HAQ08_RS16240	COG0583	DNA-binding transcription factor activity
HAQ08_RS16245	COG3634	alkyl hydroperoxide reductase activity
HAQ08_RS16255	COG2890	protein-(glutamine-N5) methyltransferase activity
HAQ08_RS16295	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAQ08_RS16295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAQ08_RS16310	COG3039	Transposase
HAQ08_RS16320	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HAQ08_RS16345	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HAQ08_RS16370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HAQ08_RS16380	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HAQ08_RS16410	COG1295	ribonuclease BN
HAQ08_RS16415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HAQ08_RS16435	COG0521	Mo-molybdopterin cofactor biosynthetic process
HAQ08_RS16445	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HAQ08_RS16450	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HAQ08_RS16460	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HAQ08_RS16475	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAQ08_RS16485	COG0193	aminoacyl-tRNA hydrolase activity
HAQ08_RS16490	COG0012	GTP binding
HAQ08_RS16520	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HAQ08_RS16525	COG0250	Participates in transcription elongation, termination and antitermination
HAQ08_RS16530	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HAQ08_RS16540	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HAQ08_RS16545	COG0222	ribosome binding
HAQ08_RS16550	COG0085	RNA polymerase activity
HAQ08_RS16555	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAQ08_RS16560	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HAQ08_RS16565	COG0049	tRNA binding
HAQ08_RS16585	COG0051	transcription antitermination factor activity, RNA binding
HAQ08_RS16590	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HAQ08_RS16595	COG0088	Forms part of the polypeptide exit tunnel
HAQ08_RS16600	COG0089	rRNA binding
HAQ08_RS16615	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HAQ08_RS16625	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HAQ08_RS16630	COG0255	Belongs to the universal ribosomal protein uL29 family
HAQ08_RS16635	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HAQ08_RS16640	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HAQ08_RS16650	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HAQ08_RS16680	COG1841	ribosomal large subunit assembly
HAQ08_RS16690	COG0201	protein transport
HAQ08_RS16700	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HAQ08_RS16705	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HAQ08_RS16775	COG3551	Protein conserved in bacteria
HAQ08_RS16805	COG2194	sulfuric ester hydrolase activity
HAQ08_RS16815	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HAQ08_RS16820	COG0745	RESPONSE REGULATOR receiver
HAQ08_RS16825	COG0642	Histidine kinase
HAQ08_RS16835	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HAQ08_RS16840	COG2894	cell division
HAQ08_RS16855	COG4585	Histidine kinase
HAQ08_RS16860	COG2197	response regulator
HAQ08_RS16875	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HAQ08_RS16955	COG3501	Rhs element vgr protein
HAQ08_RS17005	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HAQ08_RS17010	COG3501	Rhs element vgr protein
HAQ08_RS17015	COG3501	Rhs element vgr protein
HAQ08_RS17055	COG3039	Transposase
HAQ08_RS17130	COG3501	Rhs element vgr protein
HAQ08_RS17145	COG3501	Rhs element vgr protein
HAQ08_RS17155	COG3179	chitinase
HAQ08_RS17160	COG3501	Rhs element vgr protein
HAQ08_RS17225	COG3501	Rhs element vgr protein
HAQ08_RS17250	COG3501	Rhs element vgr protein
HAQ08_RS17325	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HAQ08_RS17345	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HAQ08_RS17350	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
HAQ08_RS17355	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
HAQ08_RS17370	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HAQ08_RS17405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HAQ08_RS17470	COG1297	OPT oligopeptide transporter protein
HAQ08_RS17490	COG0823	Involved in the tonB-independent uptake of proteins
HAQ08_RS17490	COG1506	peptidase
HAQ08_RS17510	COG1917	Cupin 2, conserved barrel domain protein
HAQ08_RS17510	COG2207	Transcriptional regulator
HAQ08_RS17535	COG0753	catalase activity
HAQ08_RS17575	COG0469	pyruvate kinase activity
HAQ08_RS17580	COG3588	fructose-bisphosphate aldolase
HAQ08_RS17585	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HAQ08_RS17635	COG2198	Histidine kinase
HAQ08_RS17635	COG0784	Response regulator, receiver
HAQ08_RS17635	COG2205	protein histidine kinase activity
HAQ08_RS17655	COG0175	sulfate reduction
HAQ08_RS17660	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HAQ08_RS17665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HAQ08_RS17670	COG0175	sulfate reduction
HAQ08_RS17675	COG0529	Catalyzes the synthesis of activated sulfate
HAQ08_RS17675	COG2895	sulfate adenylyltransferase (ATP) activity
HAQ08_RS17685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAQ08_RS17690	COG0308	aminopeptidase N
HAQ08_RS17715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAQ08_RS17745	COG1970	mechanosensitive ion channel activity
HAQ08_RS17775	COG0471	metal ion transport
HAQ08_RS17775	COG3273	potassium ion transport
HAQ08_RS17785	COG2022	thiamine diphosphate biosynthetic process
HAQ08_RS17870	COG3039	Transposase
HAQ08_RS17875	COG3039	Transposase
HAQ08_RS17945	COG3118	belongs to the thioredoxin family
HAQ08_RS17970	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HAQ08_RS17995	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HAQ08_RS18025	COG2968	Membrane
HAQ08_RS18035	COG1530	ribonuclease E activity
HAQ08_RS18040	COG3164	Protein of unknown function
HAQ08_RS18070	COG0312	modulator of DNA gyrase
HAQ08_RS18080	COG0312	modulator of DNA gyrase
HAQ08_RS18105	COG0142	geranyltranstransferase activity
HAQ08_RS18110	COG1722	exodeoxyribonuclease VII activity
HAQ08_RS18115	COG0037	tRNA processing
HAQ08_RS18120	COG1785	Belongs to the alkaline phosphatase family
HAQ08_RS18125	COG1301	dicarboxylic acid transport
HAQ08_RS18140	COG0791	NLP P60 protein
HAQ08_RS18145	COG0791	NLP P60 protein
HAQ08_RS18150	COG1047	Peptidyl-prolyl cis-trans
HAQ08_RS18155	COG2311	Membrane
HAQ08_RS18160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAQ08_RS18200	COG0489	protein tyrosine kinase activity
HAQ08_RS18205	COG0717	Belongs to the dCTP deaminase family
HAQ08_RS18225	COG0412	Dienelactone hydrolase
HAQ08_RS18235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HAQ08_RS18280	COG2890	protein-(glutamine-N5) methyltransferase activity
HAQ08_RS18285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HAQ08_RS18290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAQ08_RS18295	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HAQ08_RS18315	COG0101	tRNA pseudouridine synthase activity
HAQ08_RS18320	COG0135	phosphoribosylanthranilate isomerase activity
HAQ08_RS18345	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HAQ08_RS18350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAQ08_RS18400	COG0149	triose-phosphate isomerase activity
HAQ08_RS18415	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HAQ08_RS18425	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HAQ08_RS18430	COG0649	NAD binding
HAQ08_RS18435	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HAQ08_RS18440	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HAQ08_RS18445	COG1034	ATP synthesis coupled electron transport
HAQ08_RS18450	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HAQ08_RS18480	COG1007	ATP synthesis coupled electron transport
HAQ08_RS18490	COG0779	Required for maturation of 30S ribosomal subunits
HAQ08_RS18495	COG0195	Participates in both transcription termination and antitermination
HAQ08_RS18515	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HAQ08_RS18520	COG1185	polyribonucleotide nucleotidyltransferase activity
HAQ08_RS18555	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HAQ08_RS18565	COG2095	MarC family integral membrane protein
HAQ08_RS18580	COG1611	Belongs to the LOG family
HAQ08_RS18620	COG4969	Belongs to the N-Me-Phe pilin family
HAQ08_RS18625	COG0556	nucleotide-excision repair
HAQ08_RS18660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HAQ08_RS18730	COG0438	transferase activity, transferring glycosyl groups
HAQ08_RS18735	COG0438	transferase activity, transferring glycosyl groups
HAQ08_RS18745	COG0438	transferase activity, transferring glycosyl groups
HAQ08_RS18790	COG3040	lipid binding
HAQ08_RS18900	COG0552	protein localization to endoplasmic reticulum
HAQ08_RS18910	COG3938	Belongs to the proline racemase family
HAQ08_RS18915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAQ08_RS18930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAQ08_RS18940	COG0006	proline dipeptidase activity
HAQ08_RS18955	COG0531	amino acid
HAQ08_RS19005	COG4206	TonB-dependent receptor
HAQ08_RS19080	COG0746	molybdenum cofactor guanylyltransferase activity
HAQ08_RS19105	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HAQ08_RS19105	COG1648	precorrin-2 dehydrogenase activity
HAQ08_RS19145	COG3039	Transposase
HAQ08_RS19150	COG3039	Transposase
HAQ08_RS19185	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HAQ08_RS19225	COG1530	ribonuclease E activity
HAQ08_RS19235	COG3064	Membrane
HAQ08_RS19240	COG0428	transporter
HAQ08_RS19245	COG0428	transporter
HAQ08_RS19270	COG3039	Transposase
HAQ08_RS19305	COG3039	Transposase
HAQ08_RS19320	COG3039	Transposase
HAQ08_RS19395	COG3501	Rhs element vgr protein
HAQ08_RS19430	COG0631	protein serine/threonine phosphatase activity
HAQ08_RS19435	COG0515	serine threonine protein kinase
HAQ08_RS19465	COG1858	cytochrome C peroxidase
HAQ08_RS19515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAQ08_RS19520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAQ08_RS19540	COG2201	protein-glutamate methylesterase activity
HAQ08_RS19585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HAQ08_RS19605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HAQ08_RS19620	COG1595	DNA-templated transcription, initiation
HAQ08_RS19670	COG2244	polysaccharide biosynthetic process
HAQ08_RS19700	COG2264	protein methyltransferase activity
HAQ08_RS19710	COG0438	transferase activity, transferring glycosyl groups
HAQ08_RS19725	COG1136	(ABC) transporter
HAQ08_RS19730	COG1132	(ABC) transporter
HAQ08_RS19740	COG0477	Major facilitator Superfamily
HAQ08_RS19750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAQ08_RS19765	COG1253	flavin adenine dinucleotide binding
HAQ08_RS19775	COG0306	phosphate transporter
HAQ08_RS19805	COG0504	CTP synthase activity
HAQ08_RS19810	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HAQ08_RS19820	COG0148	phosphopyruvate hydratase activity
HAQ08_RS19825	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HAQ08_RS19830	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HAQ08_RS19840	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HAQ08_RS19850	COG2840	Smr protein MutS2
HAQ08_RS19855	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HAQ08_RS19860	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HAQ08_RS19865	COG1238	metal cluster binding
HAQ08_RS19880	COG1534	Rna-binding protein
HAQ08_RS19885	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HAQ08_RS19895	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HAQ08_RS19910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HAQ08_RS19915	COG1546	Belongs to the CinA family
HAQ08_RS19930	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HAQ08_RS19935	COG2137	regulation of response to DNA damage stimulus
HAQ08_RS19940	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HAQ08_RS19945	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HAQ08_RS19965	COG0305	Participates in initiation and elongation during chromosome replication
HAQ08_RS19970	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HAQ08_RS19990	COG1741	Belongs to the pirin family
HAQ08_RS19995	COG0583	DNA-binding transcription factor activity
HAQ08_RS20025	COG0351	phosphomethylpyrimidine kinase
HAQ08_RS20035	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HAQ08_RS20040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HAQ08_RS20055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAQ08_RS20065	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HAQ08_RS20070	COG3734	2-keto-3-deoxy-galactonokinase
HAQ08_RS20080	COG4948	Mandelate Racemase Muconate Lactonizing
HAQ08_RS20085	COG0800	Aldolase
HAQ08_RS20100	COG1501	Belongs to the glycosyl hydrolase 31 family
HAQ08_RS20110	COG1070	Carbohydrate kinase
HAQ08_RS20120	COG0477	Major facilitator Superfamily
HAQ08_RS20140	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HAQ08_RS20190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HAQ08_RS20195	COG2258	MOSC domain
HAQ08_RS20205	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HAQ08_RS20210	COG0505	Belongs to the CarA family
HAQ08_RS20220	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HAQ08_RS20225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HAQ08_RS20235	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HAQ08_RS20310	COG0784	Response regulator, receiver
HAQ08_RS20310	COG2198	Histidine kinase
HAQ08_RS20310	COG2205	protein histidine kinase activity
HAQ08_RS20315	COG1024	Enoyl-CoA hydratase
HAQ08_RS20320	COG0318	PFAM AMP-dependent synthetase and ligase
HAQ08_RS20350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAQ08_RS20385	COG0840	transmembrane signaling receptor activity
HAQ08_RS20405	COG0835	chemotaxis
HAQ08_RS20420	COG0840	transmembrane signaling receptor activity
HAQ08_RS20425	COG0840	transmembrane signaling receptor activity
HAQ08_RS20430	COG0840	transmembrane signaling receptor activity
HAQ08_RS20435	COG0840	transmembrane signaling receptor activity
HAQ08_RS20445	COG0840	transmembrane signaling receptor activity
HAQ08_RS20455	COG0840	transmembrane signaling receptor activity
HAQ08_RS20465	COG0840	transmembrane signaling receptor activity
HAQ08_RS20485	COG0745	RESPONSE REGULATOR receiver
HAQ08_RS20495	COG0835	chemotaxis
HAQ08_RS20505	COG1360	Flagellar Motor Protein
HAQ08_RS20510	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HAQ08_RS20530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HAQ08_RS20540	COG4771	TonB-dependent receptor
HAQ08_RS20565	COG3039	Transposase
HAQ08_RS20610	COG3501	Rhs element vgr protein
HAQ08_RS20625	COG3501	Rhs element vgr protein
HAQ08_RS20655	COG3039	Transposase
HAQ08_RS20670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HAQ08_RS20670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HAQ08_RS20675	COG1105	Belongs to the carbohydrate kinase PfkB family
HAQ08_RS20680	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HAQ08_RS20680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAQ08_RS20685	COG1609	Transcriptional regulator
HAQ08_RS20705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAQ08_RS20710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAQ08_RS20720	COG2902	Dehydrogenase
HAQ08_RS20725	COG3039	Transposase
HAQ08_RS20740	COG0477	Major facilitator Superfamily
HAQ08_RS20755	COG2205	protein histidine kinase activity
HAQ08_RS20755	COG0784	Response regulator, receiver
HAQ08_RS20755	COG5002	protein histidine kinase activity
HAQ08_RS20760	COG2733	membrane
HAQ08_RS20775	COG3039	Transposase
HAQ08_RS20795	COG2223	nitrite transmembrane transporter activity
HAQ08_RS20805	COG0243	molybdopterin cofactor binding
HAQ08_RS20815	COG0477	Major facilitator Superfamily
HAQ08_RS20825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAQ08_RS20830	COG0174	glutamine synthetase
HAQ08_RS20865	COG3842	ATPase activity
HAQ08_RS20875	COG1177	transmembrane transport
HAQ08_RS20885	COG1012	belongs to the aldehyde dehydrogenase family
HAQ08_RS20900	COG4535	Mg2 and Co2 transporter CorC
HAQ08_RS20920	COG1702	phosphate starvation-inducible protein PhoH
HAQ08_RS20945	COG0741	lytic transglycosylase activity
HAQ08_RS20950	COG0723	plastoquinol--plastocyanin reductase activity
HAQ08_RS20955	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HAQ08_RS20960	COG2857	Cytochrome c1
HAQ08_RS20965	COG0625	glutathione transferase activity
HAQ08_RS20970	COG2969	positive regulation of protein catabolic process
HAQ08_RS21010	COG3328	transposase activity
HAQ08_RS21085	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HAQ08_RS21105	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HAQ08_RS21110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HAQ08_RS21110	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HAQ08_RS21115	COG0802	atpase or kinase
HAQ08_RS21120	COG0860	N-Acetylmuramoyl-L-alanine amidase
HAQ08_RS21125	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HAQ08_RS21145	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ08_RS21165	COG2081	HI0933 family
HAQ08_RS21170	COG4681	YaeQ
HAQ08_RS21175	COG1671	Belongs to the UPF0178 family
HAQ08_RS21185	COG0625	glutathione transferase activity
HAQ08_RS21205	COG0513	Belongs to the DEAD box helicase family
HAQ08_RS21230	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HAQ08_RS21235	COG0483	inositol monophosphate 1-phosphatase activity
HAQ08_RS21250	COG5001	Diguanylate cyclase
HAQ08_RS21250	COG3300	MHYT domain
HAQ08_RS21255	COG1509	lysine 2,3-aminomutase activity
HAQ08_RS21270	COG0402	S-adenosylhomocysteine deaminase activity
HAQ08_RS21275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HAQ08_RS21290	COG4677	pectinesterase activity
HAQ08_RS21300	COG3039	Transposase
HAQ08_RS21335	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HAQ08_RS21360	COG2166	iron-sulfur cluster assembly
HAQ08_RS21375	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HAQ08_RS21380	COG0137	argininosuccinate synthase activity
HAQ08_RS21390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HAQ08_RS21395	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HAQ08_RS21410	COG0165	Argininosuccinate lyase
HAQ08_RS21465	COG3039	Transposase
HAQ08_RS21480	COG4988	ABC transporter
HAQ08_RS21485	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HAQ08_RS21495	COG3039	Transposase
HAQ08_RS21595	COG0643	Histidine kinase
HAQ08_RS21595	COG0784	Response regulator, receiver
HAQ08_RS21595	COG2198	Histidine kinase
HAQ08_RS21640	COG3300	MHYT domain
HAQ08_RS21640	COG5001	Diguanylate cyclase
HAQ08_RS21645	COG5001	Diguanylate cyclase
HAQ08_RS21645	COG3300	MHYT domain
HAQ08_RS21650	COG1684	flagellar biosynthetic protein fliR
HAQ08_RS21665	COG3190	flagellar
HAQ08_RS21715	COG1677	Flagellar hook-basal body complex protein FliE
HAQ08_RS21745	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ08_RS21755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAQ08_RS21775	COG2201	protein-glutamate methylesterase activity
HAQ08_RS21805	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HAQ08_RS21810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HAQ08_RS21850	COG4787	bacterial-type flagellum-dependent cell motility
HAQ08_RS21860	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HAQ08_RS21865	COG1558	bacterial-type flagellum-dependent cell motility
HAQ08_RS21875	COG0784	Response regulator, receiver
HAQ08_RS21875	COG0835	chemotaxis
HAQ08_RS21895	COG5002	protein histidine kinase activity
HAQ08_RS21905	COG4585	Histidine kinase
HAQ08_RS21910	COG5001	Diguanylate cyclase
HAQ08_RS21935	COG0482	sulfurtransferase activity
HAQ08_RS21950	COG0542	response to heat
HAQ08_RS21975	COG0492	ferredoxin-NADP+ reductase activity
HAQ08_RS21980	COG1674	ftsk spoiiie
HAQ08_RS22000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HAQ08_RS22020	COG0038	chloride channel
HAQ08_RS22025	COG0183	Belongs to the thiolase family
HAQ08_RS22030	COG1250	3-hydroxyacyl-CoA dehydrogenase
HAQ08_RS22030	COG1024	Enoyl-CoA hydratase
HAQ08_RS22045	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HAQ08_RS22055	COG1426	Protein conserved in bacteria
HAQ08_RS22065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAQ08_RS22075	COG0303	'Molybdopterin
HAQ08_RS22135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HAQ08_RS22155	COG0742	ribosomal rna small subunit methyltransferase
HAQ08_RS22160	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HAQ08_RS22170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HAQ08_RS22175	COG0405	Gamma-glutamyltransferase
HAQ08_RS22230	COG3039	Transposase
HAQ08_RS22270	COG0343	queuine tRNA-ribosyltransferase activity
HAQ08_RS22275	COG1862	Preprotein translocase
HAQ08_RS22280	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HAQ08_RS22285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HAQ08_RS22315	COG3328	transposase activity
HAQ08_RS22330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HAQ08_RS22340	COG0704	Plays a role in the regulation of phosphate uptake
HAQ08_RS22355	COG0573	inorganic phosphate transmembrane transporter activity
HAQ08_RS22360	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HAQ08_RS22395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HAQ08_RS22405	COG1024	Enoyl-CoA hydratase
HAQ08_RS22420	COG0494	nUDIX hydrolase
HAQ08_RS22495	COG0667	Aldo Keto reductase
HAQ08_RS22505	COG2925	Exonuclease
HAQ08_RS22540	COG0288	reversible hydration of carbon dioxide
HAQ08_RS22570	COG0316	Belongs to the HesB IscA family
HAQ08_RS22575	COG0360	Binds together with S18 to 16S ribosomal RNA
HAQ08_RS22585	COG0359	binds to the 23S rRNA
HAQ08_RS22595	COG3115	cell septum assembly
HAQ08_RS22610	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HAQ08_RS22625	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HAQ08_RS22650	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HAQ08_RS22660	COG2986	histidine ammonia-lyase
HAQ08_RS22665	COG1228	amidohydrolase
HAQ08_RS22705	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HAQ08_RS22715	COG0077	Prephenate dehydratase
HAQ08_RS22715	COG1605	Chorismate mutase
HAQ08_RS22720	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HAQ08_RS22745	COG3039	Transposase
HAQ08_RS22760	COG4566	intracellular signal transduction
HAQ08_RS22805	COG0860	N-Acetylmuramoyl-L-alanine amidase
HAQ08_RS22810	COG1469	GTP cyclohydrolase I activity
HAQ08_RS22820	COG0617	tRNA 3'-terminal CCA addition
HAQ08_RS22830	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HAQ08_RS22835	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HAQ08_RS22865	COG1472	Belongs to the glycosyl hydrolase 3 family
HAQ08_RS22885	COG2203	Gaf domain
HAQ08_RS22885	COG3706	GGDEF domain
HAQ08_RS22885	COG4251	negative regulation of phosphorylation
HAQ08_RS22885	COG5001	Diguanylate cyclase
HAQ08_RS22970	COG0386	Belongs to the glutathione peroxidase family
HAQ08_RS23025	COG3706	GGDEF domain
HAQ08_RS23050	COG5002	protein histidine kinase activity
HAQ08_RS23050	COG0784	Response regulator, receiver
HAQ08_RS23050	COG2205	protein histidine kinase activity
HAQ08_RS23080	COG0800	Aldolase
HAQ08_RS23085	COG0129	dihydroxy-acid dehydratase activity
HAQ08_RS23090	COG0363	glucosamine-6-phosphate deaminase activity
HAQ08_RS23100	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HAQ08_RS23115	COG0354	folic acid binding
HAQ08_RS23130	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HAQ08_RS23145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HAQ08_RS23160	COG4591	ABC-type transport system involved in lipoprotein release permease component
HAQ08_RS23185	COG0811	peptide transport
HAQ08_RS23200	COG1663	tetraacyldisaccharide 4'-kinase activity
HAQ08_RS23210	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HAQ08_RS23220	COG0322	excinuclease ABC activity
HAQ08_RS23250	COG3039	Transposase
HAQ08_RS23260	COG3328	transposase activity
HAQ08_RS23280	COG3039	Transposase
HAQ08_RS23300	COG2801	Transposase and inactivated derivatives
HAQ08_RS23310	COG2201	protein-glutamate methylesterase activity
HAQ08_RS23450	COG0653	protein targeting
HAQ08_RS23485	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HAQ08_RS23485	COG0140	phosphoribosyl-ATP diphosphatase activity
HAQ08_RS23495	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HAQ08_RS23505	COG0131	Imidazoleglycerol-phosphate dehydratase
HAQ08_RS23505	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HAQ08_RS23520	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HAQ08_RS23540	COG0124	histidyl-tRNA synthetase
HAQ08_RS23555	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine