locus-tag	class	description
HAQ10_RS00030	COG5002	protein histidine kinase activity
HAQ10_RS00030	COG2205	protein histidine kinase activity
HAQ10_RS00030	COG0784	Response regulator, receiver
HAQ10_RS00055	COG3706	GGDEF domain
HAQ10_RS00110	COG0386	Belongs to the glutathione peroxidase family
HAQ10_RS00195	COG3706	GGDEF domain
HAQ10_RS00195	COG2203	Gaf domain
HAQ10_RS00195	COG5001	Diguanylate cyclase
HAQ10_RS00195	COG4251	negative regulation of phosphorylation
HAQ10_RS00215	COG1472	Belongs to the glycosyl hydrolase 3 family
HAQ10_RS00260	COG0617	tRNA 3'-terminal CCA addition
HAQ10_RS00270	COG1469	GTP cyclohydrolase I activity
HAQ10_RS00275	COG0860	N-Acetylmuramoyl-L-alanine amidase
HAQ10_RS00320	COG4566	intracellular signal transduction
HAQ10_RS00360	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HAQ10_RS00365	COG0077	Prephenate dehydratase
HAQ10_RS00365	COG1605	Chorismate mutase
HAQ10_RS00375	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HAQ10_RS00415	COG1228	amidohydrolase
HAQ10_RS00420	COG2986	histidine ammonia-lyase
HAQ10_RS00430	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HAQ10_RS00455	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HAQ10_RS00470	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HAQ10_RS00485	COG3115	cell septum assembly
HAQ10_RS00495	COG0359	binds to the 23S rRNA
HAQ10_RS00505	COG0360	Binds together with S18 to 16S ribosomal RNA
HAQ10_RS00510	COG0316	Belongs to the HesB IscA family
HAQ10_RS00540	COG0288	reversible hydration of carbon dioxide
HAQ10_RS00565	COG2925	Exonuclease
HAQ10_RS00575	COG0667	Aldo Keto reductase
HAQ10_RS00600	COG0116	Belongs to the methyltransferase superfamily
HAQ10_RS00600	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HAQ10_RS00645	COG0494	nUDIX hydrolase
HAQ10_RS00655	COG1024	Enoyl-CoA hydratase
HAQ10_RS00665	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HAQ10_RS00680	COG3039	Transposase
HAQ10_RS00720	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HAQ10_RS00725	COG0573	inorganic phosphate transmembrane transporter activity
HAQ10_RS00740	COG0704	Plays a role in the regulation of phosphate uptake
HAQ10_RS00750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HAQ10_RS00765	COG3328	transposase activity
HAQ10_RS00795	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HAQ10_RS00800	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HAQ10_RS00805	COG1862	Preprotein translocase
HAQ10_RS00810	COG0343	queuine tRNA-ribosyltransferase activity
HAQ10_RS00885	COG0405	Gamma-glutamyltransferase
HAQ10_RS00890	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HAQ10_RS00900	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HAQ10_RS00905	COG0742	ribosomal rna small subunit methyltransferase
HAQ10_RS00925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HAQ10_RS00960	COG3039	Transposase
HAQ10_RS00970	COG3039	Transposase
HAQ10_RS01000	COG0303	'Molybdopterin
HAQ10_RS01010	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAQ10_RS01020	COG1426	Protein conserved in bacteria
HAQ10_RS01030	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HAQ10_RS01045	COG1250	3-hydroxyacyl-CoA dehydrogenase
HAQ10_RS01045	COG1024	Enoyl-CoA hydratase
HAQ10_RS01050	COG0183	Belongs to the thiolase family
HAQ10_RS01055	COG0038	chloride channel
HAQ10_RS01075	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HAQ10_RS01095	COG1674	ftsk spoiiie
HAQ10_RS01100	COG0492	ferredoxin-NADP+ reductase activity
HAQ10_RS01125	COG0542	response to heat
HAQ10_RS01165	COG5001	Diguanylate cyclase
HAQ10_RS01170	COG4585	Histidine kinase
HAQ10_RS01180	COG5002	protein histidine kinase activity
HAQ10_RS01200	COG0835	chemotaxis
HAQ10_RS01200	COG0784	Response regulator, receiver
HAQ10_RS01210	COG1558	bacterial-type flagellum-dependent cell motility
HAQ10_RS01215	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HAQ10_RS01225	COG4787	bacterial-type flagellum-dependent cell motility
HAQ10_RS01265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HAQ10_RS01270	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HAQ10_RS01300	COG2201	protein-glutamate methylesterase activity
HAQ10_RS01320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAQ10_RS01330	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ10_RS01360	COG1677	Flagellar hook-basal body complex protein FliE
HAQ10_RS01410	COG3190	flagellar
HAQ10_RS01425	COG1684	flagellar biosynthetic protein fliR
HAQ10_RS01430	COG5001	Diguanylate cyclase
HAQ10_RS01430	COG3300	MHYT domain
HAQ10_RS01435	COG3300	MHYT domain
HAQ10_RS01435	COG5001	Diguanylate cyclase
HAQ10_RS01480	COG0643	Histidine kinase
HAQ10_RS01480	COG2198	Histidine kinase
HAQ10_RS01480	COG0784	Response regulator, receiver
HAQ10_RS01510	COG3039	Transposase
HAQ10_RS01520	COG3209	COG3209 Rhs family protein
HAQ10_RS01530	COG3039	Transposase
HAQ10_RS01540	COG3039	Transposase
HAQ10_RS01620	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HAQ10_RS01625	COG4988	ABC transporter
HAQ10_RS01645	COG1271	oxidase subunit
HAQ10_RS01680	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HAQ10_RS01700	COG0165	Argininosuccinate lyase
HAQ10_RS01715	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HAQ10_RS01720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HAQ10_RS01730	COG0137	argininosuccinate synthase activity
HAQ10_RS01735	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HAQ10_RS01750	COG2166	iron-sulfur cluster assembly
HAQ10_RS01775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HAQ10_RS01810	COG3039	Transposase
HAQ10_RS01820	COG4677	pectinesterase activity
HAQ10_RS01845	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HAQ10_RS01850	COG0402	S-adenosylhomocysteine deaminase activity
HAQ10_RS01865	COG1509	lysine 2,3-aminomutase activity
HAQ10_RS01870	COG3300	MHYT domain
HAQ10_RS01870	COG5001	Diguanylate cyclase
HAQ10_RS01885	COG0483	inositol monophosphate 1-phosphatase activity
HAQ10_RS01890	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HAQ10_RS01915	COG0513	Belongs to the DEAD box helicase family
HAQ10_RS01935	COG0625	glutathione transferase activity
HAQ10_RS01945	COG1671	Belongs to the UPF0178 family
HAQ10_RS01950	COG4681	YaeQ
HAQ10_RS01955	COG2081	HI0933 family
HAQ10_RS01975	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ10_RS01995	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HAQ10_RS02000	COG0860	N-Acetylmuramoyl-L-alanine amidase
HAQ10_RS02005	COG0802	atpase or kinase
HAQ10_RS02010	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HAQ10_RS02010	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HAQ10_RS02015	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HAQ10_RS02035	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HAQ10_RS02110	COG3328	transposase activity
HAQ10_RS02145	COG2969	positive regulation of protein catabolic process
HAQ10_RS02150	COG0625	glutathione transferase activity
HAQ10_RS02155	COG2857	Cytochrome c1
HAQ10_RS02160	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HAQ10_RS02165	COG0723	plastoquinol--plastocyanin reductase activity
HAQ10_RS02170	COG0741	lytic transglycosylase activity
HAQ10_RS02195	COG1702	phosphate starvation-inducible protein PhoH
HAQ10_RS02215	COG4535	Mg2 and Co2 transporter CorC
HAQ10_RS02230	COG1012	belongs to the aldehyde dehydrogenase family
HAQ10_RS02240	COG1177	transmembrane transport
HAQ10_RS02250	COG3842	ATPase activity
HAQ10_RS02285	COG0174	glutamine synthetase
HAQ10_RS02290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAQ10_RS02300	COG0477	Major facilitator Superfamily
HAQ10_RS02310	COG0243	molybdopterin cofactor binding
HAQ10_RS02320	COG2223	nitrite transmembrane transporter activity
HAQ10_RS02340	COG1121	(ABC) transporter
HAQ10_RS02350	COG2733	membrane
HAQ10_RS02355	COG0784	Response regulator, receiver
HAQ10_RS02355	COG5002	protein histidine kinase activity
HAQ10_RS02355	COG2205	protein histidine kinase activity
HAQ10_RS02365	COG3039	Transposase
HAQ10_RS02370	COG2902	Dehydrogenase
HAQ10_RS02380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAQ10_RS02385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAQ10_RS02405	COG1609	Transcriptional regulator
HAQ10_RS02410	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HAQ10_RS02410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAQ10_RS02415	COG1105	Belongs to the carbohydrate kinase PfkB family
HAQ10_RS02420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HAQ10_RS02420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HAQ10_RS02435	COG3039	Transposase
HAQ10_RS02465	COG3039	Transposase
HAQ10_RS02490	COG3501	Rhs element vgr protein
HAQ10_RS02530	COG3501	Rhs element vgr protein
HAQ10_RS02575	COG3039	Transposase
HAQ10_RS02580	COG3039	Transposase
HAQ10_RS02590	COG3039	Transposase
HAQ10_RS02615	COG4771	TonB-dependent receptor
HAQ10_RS02625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HAQ10_RS02645	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HAQ10_RS02650	COG1360	Flagellar Motor Protein
HAQ10_RS02660	COG0835	chemotaxis
HAQ10_RS02670	COG0745	RESPONSE REGULATOR receiver
HAQ10_RS02690	COG0840	transmembrane signaling receptor activity
HAQ10_RS02700	COG0840	transmembrane signaling receptor activity
HAQ10_RS02710	COG0840	transmembrane signaling receptor activity
HAQ10_RS02720	COG0840	transmembrane signaling receptor activity
HAQ10_RS02725	COG0840	transmembrane signaling receptor activity
HAQ10_RS02730	COG0840	transmembrane signaling receptor activity
HAQ10_RS02735	COG0840	transmembrane signaling receptor activity
HAQ10_RS02750	COG0835	chemotaxis
HAQ10_RS02770	COG0840	transmembrane signaling receptor activity
HAQ10_RS02805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAQ10_RS02835	COG0318	PFAM AMP-dependent synthetase and ligase
HAQ10_RS02840	COG1024	Enoyl-CoA hydratase
HAQ10_RS02845	COG0784	Response regulator, receiver
HAQ10_RS02845	COG2205	protein histidine kinase activity
HAQ10_RS02845	COG2198	Histidine kinase
HAQ10_RS02920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HAQ10_RS02930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HAQ10_RS02935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HAQ10_RS02945	COG0505	Belongs to the CarA family
HAQ10_RS02950	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HAQ10_RS02960	COG2258	MOSC domain
HAQ10_RS02965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HAQ10_RS03015	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HAQ10_RS03035	COG0477	Major facilitator Superfamily
HAQ10_RS03045	COG1070	Carbohydrate kinase
HAQ10_RS03055	COG1501	Belongs to the glycosyl hydrolase 31 family
HAQ10_RS03070	COG0800	Aldolase
HAQ10_RS03075	COG4948	Mandelate Racemase Muconate Lactonizing
HAQ10_RS03085	COG3734	2-keto-3-deoxy-galactonokinase
HAQ10_RS03090	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HAQ10_RS03100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAQ10_RS03115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HAQ10_RS03120	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HAQ10_RS03130	COG0351	phosphomethylpyrimidine kinase
HAQ10_RS03160	COG0583	DNA-binding transcription factor activity
HAQ10_RS03165	COG1741	Belongs to the pirin family
HAQ10_RS03185	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HAQ10_RS03190	COG0305	Participates in initiation and elongation during chromosome replication
HAQ10_RS03210	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HAQ10_RS03215	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HAQ10_RS03220	COG2137	regulation of response to DNA damage stimulus
HAQ10_RS03225	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HAQ10_RS03240	COG1546	Belongs to the CinA family
HAQ10_RS03245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HAQ10_RS03260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HAQ10_RS03270	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HAQ10_RS03275	COG1534	Rna-binding protein
HAQ10_RS03290	COG1238	metal cluster binding
HAQ10_RS03295	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HAQ10_RS03300	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HAQ10_RS03305	COG2840	Smr protein MutS2
HAQ10_RS03315	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HAQ10_RS03330	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HAQ10_RS03335	COG0148	phosphopyruvate hydratase activity
HAQ10_RS03345	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HAQ10_RS03350	COG0504	CTP synthase activity
HAQ10_RS03375	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HAQ10_RS03380	COG0306	phosphate transporter
HAQ10_RS03390	COG1253	flavin adenine dinucleotide binding
HAQ10_RS03405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAQ10_RS03415	COG0477	Major facilitator Superfamily
HAQ10_RS03425	COG1132	(ABC) transporter
HAQ10_RS03430	COG1136	(ABC) transporter
HAQ10_RS03450	COG0438	transferase activity, transferring glycosyl groups
HAQ10_RS03460	COG2264	protein methyltransferase activity
HAQ10_RS03490	COG2244	polysaccharide biosynthetic process
HAQ10_RS03540	COG1595	DNA-templated transcription, initiation
HAQ10_RS03555	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HAQ10_RS03575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HAQ10_RS03625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAQ10_RS03630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAQ10_RS03680	COG1858	cytochrome C peroxidase
HAQ10_RS03715	COG0515	serine threonine protein kinase
HAQ10_RS03720	COG0631	protein serine/threonine phosphatase activity
HAQ10_RS03755	COG3501	Rhs element vgr protein
HAQ10_RS03830	COG3039	Transposase
HAQ10_RS03845	COG3039	Transposase
HAQ10_RS03905	COG0428	transporter
HAQ10_RS03910	COG0428	transporter
HAQ10_RS03915	COG3064	Membrane
HAQ10_RS03925	COG1530	ribonuclease E activity
HAQ10_RS03950	COG3039	Transposase
HAQ10_RS03970	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HAQ10_RS04005	COG3039	Transposase
HAQ10_RS04010	COG3039	Transposase
HAQ10_RS04050	COG1648	precorrin-2 dehydrogenase activity
HAQ10_RS04050	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HAQ10_RS04075	COG0746	molybdenum cofactor guanylyltransferase activity
HAQ10_RS04140	COG3328	transposase activity
HAQ10_RS04145	COG4206	TonB-dependent receptor
HAQ10_RS04170	COG4206	TonB-dependent receptor
HAQ10_RS04220	COG0531	amino acid
HAQ10_RS04235	COG0006	proline dipeptidase activity
HAQ10_RS04245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAQ10_RS04260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAQ10_RS04265	COG3938	Belongs to the proline racemase family
HAQ10_RS04275	COG0552	protein localization to endoplasmic reticulum
HAQ10_RS04295	COG0784	Response regulator, receiver
HAQ10_RS04295	COG4191	Histidine kinase
HAQ10_RS04385	COG3040	lipid binding
HAQ10_RS04425	COG0438	transferase activity, transferring glycosyl groups
HAQ10_RS04435	COG0438	transferase activity, transferring glycosyl groups
HAQ10_RS04440	COG0438	transferase activity, transferring glycosyl groups
HAQ10_RS04510	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HAQ10_RS04550	COG4969	Belongs to the N-Me-Phe pilin family
HAQ10_RS04590	COG1611	Belongs to the LOG family
HAQ10_RS04605	COG2095	MarC family integral membrane protein
HAQ10_RS04615	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HAQ10_RS04650	COG1185	polyribonucleotide nucleotidyltransferase activity
HAQ10_RS04655	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HAQ10_RS04675	COG0195	Participates in both transcription termination and antitermination
HAQ10_RS04680	COG0779	Required for maturation of 30S ribosomal subunits
HAQ10_RS04690	COG1007	ATP synthesis coupled electron transport
HAQ10_RS04725	COG1034	ATP synthesis coupled electron transport
HAQ10_RS04730	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HAQ10_RS04735	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HAQ10_RS04740	COG0649	NAD binding
HAQ10_RS04745	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HAQ10_RS04755	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HAQ10_RS04770	COG0149	triose-phosphate isomerase activity
HAQ10_RS04820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAQ10_RS04825	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HAQ10_RS04850	COG0135	phosphoribosylanthranilate isomerase activity
HAQ10_RS04855	COG0101	tRNA pseudouridine synthase activity
HAQ10_RS04875	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HAQ10_RS04880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAQ10_RS04885	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HAQ10_RS04890	COG2890	protein-(glutamine-N5) methyltransferase activity
HAQ10_RS04935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HAQ10_RS04945	COG0412	Dienelactone hydrolase
HAQ10_RS04965	COG0717	Belongs to the dCTP deaminase family
HAQ10_RS04970	COG0489	protein tyrosine kinase activity
HAQ10_RS05010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAQ10_RS05015	COG2311	Membrane
HAQ10_RS05020	COG1047	Peptidyl-prolyl cis-trans
HAQ10_RS05025	COG0791	NLP P60 protein
HAQ10_RS05030	COG0791	NLP P60 protein
HAQ10_RS05050	COG1301	dicarboxylic acid transport
HAQ10_RS05055	COG1785	Belongs to the alkaline phosphatase family
HAQ10_RS05060	COG0037	tRNA processing
HAQ10_RS05065	COG1722	exodeoxyribonuclease VII activity
HAQ10_RS05070	COG0142	geranyltranstransferase activity
HAQ10_RS05095	COG0312	modulator of DNA gyrase
HAQ10_RS05100	COG3028	Belongs to the UPF0307 family
HAQ10_RS05105	COG0312	modulator of DNA gyrase
HAQ10_RS05115	COG3164	Protein of unknown function
HAQ10_RS05120	COG1530	ribonuclease E activity
HAQ10_RS05130	COG2968	Membrane
HAQ10_RS05155	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HAQ10_RS05180	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HAQ10_RS05205	COG3118	belongs to the thioredoxin family
HAQ10_RS05280	COG3039	Transposase
HAQ10_RS05285	COG3039	Transposase
HAQ10_RS05365	COG2022	thiamine diphosphate biosynthetic process
HAQ10_RS05375	COG3273	potassium ion transport
HAQ10_RS05375	COG0471	metal ion transport
HAQ10_RS05405	COG1970	mechanosensitive ion channel activity
HAQ10_RS05435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAQ10_RS05455	COG0308	aminopeptidase N
HAQ10_RS05460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAQ10_RS05470	COG0529	Catalyzes the synthesis of activated sulfate
HAQ10_RS05470	COG2895	sulfate adenylyltransferase (ATP) activity
HAQ10_RS05475	COG0175	sulfate reduction
HAQ10_RS05480	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HAQ10_RS05485	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HAQ10_RS05490	COG0175	sulfate reduction
HAQ10_RS05510	COG0784	Response regulator, receiver
HAQ10_RS05510	COG2198	Histidine kinase
HAQ10_RS05510	COG2205	protein histidine kinase activity
HAQ10_RS05560	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HAQ10_RS05565	COG3588	fructose-bisphosphate aldolase
HAQ10_RS05570	COG0469	pyruvate kinase activity
HAQ10_RS05610	COG0753	catalase activity
HAQ10_RS05630	COG3039	Transposase
HAQ10_RS05650	COG1917	Cupin 2, conserved barrel domain protein
HAQ10_RS05650	COG2207	Transcriptional regulator
HAQ10_RS05680	COG1506	peptidase
HAQ10_RS05680	COG0823	Involved in the tonB-independent uptake of proteins
HAQ10_RS05700	COG3039	Transposase
HAQ10_RS05705	COG1297	OPT oligopeptide transporter protein
HAQ10_RS05800	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HAQ10_RS05805	COG3039	Transposase
HAQ10_RS05825	COG3039	Transposase
HAQ10_RS05830	COG0732	type I restriction modification DNA specificity domain
HAQ10_RS05835	COG3039	Transposase
HAQ10_RS05850	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
HAQ10_RS05855	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HAQ10_RS05875	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HAQ10_RS05980	COG3501	Rhs element vgr protein
HAQ10_RS06045	COG3501	Rhs element vgr protein
HAQ10_RS06085	COG3501	Rhs element vgr protein
HAQ10_RS06090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HAQ10_RS06140	COG3501	Rhs element vgr protein
HAQ10_RS06220	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HAQ10_RS06235	COG2197	response regulator
HAQ10_RS06240	COG4585	Histidine kinase
HAQ10_RS06255	COG2894	cell division
HAQ10_RS06260	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HAQ10_RS06270	COG0642	Histidine kinase
HAQ10_RS06275	COG0745	RESPONSE REGULATOR receiver
HAQ10_RS06280	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HAQ10_RS06290	COG2194	sulfuric ester hydrolase activity
HAQ10_RS06320	COG3551	Protein conserved in bacteria
HAQ10_RS06380	COG0203	ribosomal protein L17
HAQ10_RS06390	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HAQ10_RS06395	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HAQ10_RS06405	COG0201	protein transport
HAQ10_RS06415	COG1841	ribosomal large subunit assembly
HAQ10_RS06445	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HAQ10_RS06455	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HAQ10_RS06460	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HAQ10_RS06465	COG0255	Belongs to the universal ribosomal protein uL29 family
HAQ10_RS06470	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HAQ10_RS06480	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HAQ10_RS06495	COG0089	rRNA binding
HAQ10_RS06500	COG0088	Forms part of the polypeptide exit tunnel
HAQ10_RS06505	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HAQ10_RS06510	COG0051	transcription antitermination factor activity, RNA binding
HAQ10_RS06530	COG0049	tRNA binding
HAQ10_RS06535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HAQ10_RS06540	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAQ10_RS06545	COG0085	RNA polymerase activity
HAQ10_RS06550	COG0222	ribosome binding
HAQ10_RS06555	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HAQ10_RS06565	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HAQ10_RS06570	COG0250	Participates in transcription elongation, termination and antitermination
HAQ10_RS06575	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HAQ10_RS06605	COG0012	GTP binding
HAQ10_RS06610	COG0193	aminoacyl-tRNA hydrolase activity
HAQ10_RS06620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAQ10_RS06635	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HAQ10_RS06650	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HAQ10_RS06660	COG0521	Mo-molybdopterin cofactor biosynthetic process
HAQ10_RS06680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HAQ10_RS06685	COG1295	ribonuclease BN
HAQ10_RS06715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HAQ10_RS06725	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HAQ10_RS06750	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HAQ10_RS06775	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HAQ10_RS06790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAQ10_RS06790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAQ10_RS06840	COG2890	protein-(glutamine-N5) methyltransferase activity
HAQ10_RS06850	COG3634	alkyl hydroperoxide reductase activity
HAQ10_RS06855	COG0583	DNA-binding transcription factor activity
HAQ10_RS06860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HAQ10_RS06925	COG4783	chaperone-mediated protein folding
HAQ10_RS06940	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HAQ10_RS06950	COG0438	transferase activity, transferring glycosyl groups
HAQ10_RS06955	COG0671	phosphoesterase, PA-phosphatase related
HAQ10_RS06960	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HAQ10_RS06980	COG2833	Protein of unknown function (DUF455)
HAQ10_RS07000	COG0285	dihydrofolate synthase activity
HAQ10_RS07010	COG0406	alpha-ribazole phosphatase activity
HAQ10_RS07040	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HAQ10_RS07045	COG4208	sulfate ABC transporter
HAQ10_RS07050	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HAQ10_RS07055	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HAQ10_RS07060	COG0156	8-amino-7-oxononanoate synthase activity
HAQ10_RS07085	COG0604	alcohol dehydrogenase
HAQ10_RS07090	COG0446	pyridine nucleotide-disulphide oxidoreductase
HAQ10_RS07090	COG1902	pentaerythritol trinitrate reductase activity
HAQ10_RS07215	COG3386	PFAM SMP-30 Gluconolaconase
HAQ10_RS07235	COG1024	Enoyl-CoA hydratase
HAQ10_RS07245	COG0318	PFAM AMP-dependent synthetase and ligase
HAQ10_RS07250	COG0583	DNA-binding transcription factor activity
HAQ10_RS07290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HAQ10_RS07295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HAQ10_RS07305	COG2096	Adenosyltransferase
HAQ10_RS07310	COG0123	including yeast histone deacetylase and acetoin utilization protein
HAQ10_RS07325	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HAQ10_RS07335	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HAQ10_RS07340	COG2967	ApaG domain
HAQ10_RS07365	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HAQ10_RS07385	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HAQ10_RS07410	COG0642	Histidine kinase
HAQ10_RS07425	COG4181	ATPase activity
HAQ10_RS07435	COG2175	clavaminate synthase activity
HAQ10_RS07445	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HAQ10_RS07485	COG0667	Aldo Keto reductase
HAQ10_RS07495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HAQ10_RS07500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAQ10_RS07510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAQ10_RS07525	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HAQ10_RS07580	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HAQ10_RS07585	COG2226	methyltransferase
HAQ10_RS07630	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ10_RS07630	COG3321	synthase
HAQ10_RS07630	COG0604	alcohol dehydrogenase
HAQ10_RS07640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HAQ10_RS07655	COG0494	nUDIX hydrolase
HAQ10_RS07670	COG4942	peptidase
HAQ10_RS07670	COG1388	LysM domain
HAQ10_RS07680	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HAQ10_RS07695	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HAQ10_RS07700	COG1181	Belongs to the D-alanine--D-alanine ligase family
HAQ10_RS07705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HAQ10_RS07725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HAQ10_RS07740	COG3116	cell division
HAQ10_RS07745	COG0275	rRNA processing
HAQ10_RS07780	COG0792	nuclease activity
HAQ10_RS07785	COG1988	membrane-bound metal-dependent
HAQ10_RS07790	COG0277	FAD linked oxidase domain protein
HAQ10_RS07795	COG0745	RESPONSE REGULATOR receiver
HAQ10_RS07800	COG2205	protein histidine kinase activity
HAQ10_RS07810	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HAQ10_RS07815	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HAQ10_RS07835	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HAQ10_RS07840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAQ10_RS07845	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HAQ10_RS07865	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HAQ10_RS07865	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HAQ10_RS07885	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HAQ10_RS07905	COG0488	(ABC) transporter
HAQ10_RS07950	COG0745	RESPONSE REGULATOR receiver
HAQ10_RS07955	COG2205	protein histidine kinase activity
HAQ10_RS07990	COG2205	protein histidine kinase activity
HAQ10_RS08010	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HAQ10_RS08045	COG3039	Transposase
HAQ10_RS08050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HAQ10_RS08060	COG3039	Transposase
HAQ10_RS08070	COG3039	Transposase
HAQ10_RS08115	COG3039	Transposase
HAQ10_RS08155	COG1649	PFAM Uncharacterised BCR, COG1649
HAQ10_RS08155	COG0726	polysaccharide deacetylase
HAQ10_RS08160	COG1215	transferase activity, transferring glycosyl groups
HAQ10_RS08170	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HAQ10_RS08175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HAQ10_RS08180	COG1609	Transcriptional regulator
HAQ10_RS08190	COG2188	Transcriptional regulator
HAQ10_RS08205	COG3250	beta-galactosidase activity
HAQ10_RS08255	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HAQ10_RS08260	COG4191	Histidine kinase
HAQ10_RS08265	COG0784	Response regulator, receiver
HAQ10_RS08270	COG4251	negative regulation of phosphorylation
HAQ10_RS08275	COG2823	Periplasmic or secreted lipoprotein
HAQ10_RS08280	COG0673	inositol 2-dehydrogenase activity
HAQ10_RS08285	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HAQ10_RS08320	COG1056	cytidyltransferase-related domain
HAQ10_RS08320	COG1051	belongs to the nudix hydrolase family
HAQ10_RS08360	COG2921	Belongs to the UPF0250 family
HAQ10_RS08375	COG1686	Belongs to the peptidase S11 family
HAQ10_RS08380	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HAQ10_RS08385	COG2951	lytic endotransglycosylase activity
HAQ10_RS08405	COG5632	N-Acetylmuramoyl-L-alanine amidase
HAQ10_RS08405	COG1388	LysM domain
HAQ10_RS08405	COG3409	Peptidoglycan-binding domain 1 protein
HAQ10_RS08415	COG3501	Rhs element vgr protein
HAQ10_RS08440	COG0772	Belongs to the SEDS family
HAQ10_RS08455	COG1792	Involved in formation and maintenance of cell shape
HAQ10_RS08460	COG1077	Cell shape determining protein MreB Mrl
HAQ10_RS08465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAQ10_RS08510	COG2199	diguanylate cyclase activity
HAQ10_RS08515	COG0308	aminopeptidase N
HAQ10_RS08545	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HAQ10_RS08590	COG1505	serine-type exopeptidase activity
HAQ10_RS08615	COG0181	hydroxymethylbilane synthase activity
HAQ10_RS08625	COG3275	phosphorelay sensor kinase activity
HAQ10_RS08660	COG0659	secondary active sulfate transmembrane transporter activity
HAQ10_RS08665	COG5297	Belongs to the glycosyl hydrolase family 6
HAQ10_RS08665	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HAQ10_RS08735	COG0598	Magnesium transport protein CorA
HAQ10_RS08745	COG1113	amino acid transport
HAQ10_RS08755	COG5297	Belongs to the glycosyl hydrolase family 6
HAQ10_RS08760	COG4305	rare lipoprotein A
HAQ10_RS08765	COG0697	spore germination
HAQ10_RS08820	COG4221	oxidoreductase activity
HAQ10_RS08850	COG0456	acetyltransferase
HAQ10_RS08860	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HAQ10_RS08900	COG2111	Na H antiporter
HAQ10_RS08900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HAQ10_RS08905	COG1006	Multisubunit Na H antiporter MnhC subunit
HAQ10_RS08910	COG0651	ATP synthesis coupled electron transport
HAQ10_RS08920	COG2212	antiporter activity
HAQ10_RS08925	COG1320	monovalent cation:proton antiporter activity
HAQ10_RS08935	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HAQ10_RS08955	COG3104	oligopeptide transport
HAQ10_RS08960	COG3483	tryptophan 2,3-dioxygenase activity
HAQ10_RS08970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HAQ10_RS09005	COG0183	Belongs to the thiolase family
HAQ10_RS09055	COG3039	Transposase
HAQ10_RS09085	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HAQ10_RS09090	COG3023	N-Acetylmuramoyl-L-alanine amidase
HAQ10_RS09100	COG4948	Mandelate Racemase Muconate Lactonizing
HAQ10_RS09135	COG0531	amino acid
HAQ10_RS09170	COG4682	membrane
HAQ10_RS09175	COG2133	pyrroloquinoline quinone binding
HAQ10_RS09210	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HAQ10_RS09215	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HAQ10_RS09225	COG1610	YqeY-like protein
HAQ10_RS09240	COG1295	ribonuclease BN
HAQ10_RS09245	COG0358	DNA primase activity
HAQ10_RS09310	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HAQ10_RS09325	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HAQ10_RS09375	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HAQ10_RS09380	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HAQ10_RS09385	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
HAQ10_RS09395	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HAQ10_RS09400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HAQ10_RS09415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HAQ10_RS09490	COG3039	Transposase
HAQ10_RS09500	COG3328	transposase activity
HAQ10_RS09510	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HAQ10_RS09510	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HAQ10_RS09520	COG1473	amidohydrolase
HAQ10_RS09525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAQ10_RS09530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAQ10_RS09545	COG5383	Protein conserved in bacteria
HAQ10_RS09580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HAQ10_RS09585	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HAQ10_RS09600	COG0028	Belongs to the TPP enzyme family
HAQ10_RS09605	COG4191	Histidine kinase
HAQ10_RS09630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HAQ10_RS09645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAQ10_RS09650	COG3177	Filamentation induced by cAMP protein fic
HAQ10_RS09665	COG0596	Alpha beta hydrolase
HAQ10_RS09670	COG0727	PFAM Uncharacterised protein family (UPF0153)
HAQ10_RS09675	COG0318	PFAM AMP-dependent synthetase and ligase
HAQ10_RS09680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HAQ10_RS09730	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HAQ10_RS09740	COG0129	dihydroxy-acid dehydratase activity
HAQ10_RS09760	COG3039	Transposase
HAQ10_RS09770	COG0408	coproporphyrinogen oxidase activity
HAQ10_RS09860	COG2353	YceI-like domain
HAQ10_RS09890	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HAQ10_RS09905	COG3386	PFAM SMP-30 Gluconolaconase
HAQ10_RS09945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HAQ10_RS09965	COG0459	protein refolding
HAQ10_RS09990	COG1252	NADH dehydrogenase
HAQ10_RS10000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAQ10_RS10005	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HAQ10_RS10010	COG2201	protein-glutamate methylesterase activity
HAQ10_RS10015	COG2177	Part of the ABC transporter FtsEX involved in
HAQ10_RS10020	COG2884	Cell division ATP-binding protein ftsE
HAQ10_RS10030	COG3118	belongs to the thioredoxin family
HAQ10_RS10035	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HAQ10_RS10050	COG0729	surface antigen
HAQ10_RS10055	COG2911	Protein conserved in bacteria
HAQ10_RS10090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HAQ10_RS10105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAQ10_RS10155	COG1733	regulation of RNA biosynthetic process
HAQ10_RS10160	COG0702	epimerase
HAQ10_RS10190	COG0583	DNA-binding transcription factor activity
HAQ10_RS10195	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HAQ10_RS10215	COG0745	RESPONSE REGULATOR receiver
HAQ10_RS10245	COG1902	pentaerythritol trinitrate reductase activity
HAQ10_RS10250	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HAQ10_RS10260	COG2814	Major facilitator Superfamily
HAQ10_RS10265	COG0583	DNA-binding transcription factor activity
HAQ10_RS10280	COG0084	hydrolase, TatD family'
HAQ10_RS10330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HAQ10_RS10350	COG2072	flavoprotein involved in K transport
HAQ10_RS10395	COG4770	biotin carboxylase activity
HAQ10_RS10400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HAQ10_RS10405	COG1960	acyl-CoA dehydrogenase activity
HAQ10_RS10460	COG0523	cobalamin synthesis protein
HAQ10_RS10470	COG0697	spore germination
HAQ10_RS10480	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HAQ10_RS10495	COG4771	TonB-dependent receptor
HAQ10_RS10500	COG0457	Tetratricopeptide repeat
HAQ10_RS10515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HAQ10_RS10530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HAQ10_RS10530	COG0519	Catalyzes the synthesis of GMP from XMP
HAQ10_RS10540	COG0805	protein transport
HAQ10_RS10550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HAQ10_RS10560	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HAQ10_RS10605	COG3661	Belongs to the glycosyl hydrolase 67 family
HAQ10_RS10615	COG4948	Mandelate Racemase Muconate Lactonizing
HAQ10_RS10625	COG1472	Belongs to the glycosyl hydrolase 3 family
HAQ10_RS10630	COG0246	Mannitol dehydrogenase
HAQ10_RS10655	COG3693	PFAM glycoside hydrolase, family 10
HAQ10_RS10675	COG2211	Major facilitator Superfamily
HAQ10_RS10720	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HAQ10_RS10765	COG1846	Transcriptional regulator
HAQ10_RS10770	COG1764	response to oxidative stress
HAQ10_RS10850	COG3549	Plasmid maintenance system killer
HAQ10_RS10860	COG1074	ATP-dependent DNA helicase activity
HAQ10_RS10865	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HAQ10_RS10910	COG2032	superoxide dismutase activity
HAQ10_RS10915	COG2032	superoxide dismutase activity
HAQ10_RS10920	COG2204	response regulator
HAQ10_RS10925	COG3852	Histidine kinase
HAQ10_RS10930	COG0004	ammonium transporteR
HAQ10_RS10935	COG0347	Belongs to the P(II) protein family
HAQ10_RS10940	COG0174	glutamine synthetase
HAQ10_RS10945	COG1968	undecaprenyl-diphosphatase activity
HAQ10_RS10990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAQ10_RS11000	COG2062	phosphohistidine phosphatase, SixA
HAQ10_RS11005	COG0489	protein tyrosine kinase activity
HAQ10_RS11025	COG1396	sequence-specific DNA binding
HAQ10_RS11030	COG3550	peptidyl-serine autophosphorylation
HAQ10_RS11035	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HAQ10_RS11040	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HAQ10_RS11055	COG0517	IMP dehydrogenase activity
HAQ10_RS11055	COG1125	glycine betaine transport
HAQ10_RS11070	COG1119	ATPase activity
HAQ10_RS11080	COG1752	Esterase of the alpha-beta hydrolase superfamily
HAQ10_RS11095	COG3039	Transposase
HAQ10_RS11120	COG0656	L-ascorbic acid biosynthetic process
HAQ10_RS11125	COG2130	NADP-dependent
HAQ10_RS11130	COG0667	Aldo Keto reductase
HAQ10_RS11140	COG1187	pseudouridine synthase activity
HAQ10_RS11155	COG1643	Atp-dependent helicase
HAQ10_RS11160	COG4807	Protein conserved in bacteria
HAQ10_RS11165	COG4948	Mandelate Racemase Muconate Lactonizing
HAQ10_RS11170	COG0179	Fumarylacetoacetate (FAA) hydrolase
HAQ10_RS11175	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ10_RS11195	COG3507	Belongs to the glycosyl hydrolase 43 family
HAQ10_RS11235	COG3162	membrane
HAQ10_RS11240	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAQ10_RS11255	COG0708	Exodeoxyribonuclease III
HAQ10_RS11270	COG2091	lysine biosynthetic process via aminoadipic acid
HAQ10_RS11280	COG3540	Alkaline phosphatase
HAQ10_RS11310	COG2159	amidohydrolase
HAQ10_RS11330	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HAQ10_RS11335	COG0583	DNA-binding transcription factor activity
HAQ10_RS11340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAQ10_RS11355	COG0210	DNA helicase
HAQ10_RS11370	COG0531	amino acid
HAQ10_RS11385	COG1322	Protein conserved in bacteria
HAQ10_RS11395	COG0386	Belongs to the glutathione peroxidase family
HAQ10_RS11445	COG0793	Belongs to the peptidase S41A family
HAQ10_RS11450	COG4942	peptidase
HAQ10_RS11460	COG2234	aminopeptidase activity
HAQ10_RS11505	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAQ10_RS11510	COG0302	gtp cyclohydrolase
HAQ10_RS11535	COG0477	Major facilitator Superfamily
HAQ10_RS11545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAQ10_RS11640	COG1929	Belongs to the glycerate kinase type-1 family
HAQ10_RS11645	COG2271	Major facilitator Superfamily
HAQ10_RS11660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HAQ10_RS11665	COG0861	Integral membrane protein TerC family
HAQ10_RS11675	COG0584	glycerophosphoryl diester phosphodiesterase
HAQ10_RS11685	COG0671	phosphoesterase, PA-phosphatase related
HAQ10_RS11695	COG0726	polysaccharide deacetylase
HAQ10_RS11715	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HAQ10_RS11730	COG0187	DNA topoisomerase II activity
HAQ10_RS11740	COG0501	Belongs to the peptidase M48B family
HAQ10_RS11780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAQ10_RS11790	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HAQ10_RS11800	COG4772	TonB-dependent receptor
HAQ10_RS11815	COG3039	Transposase
HAQ10_RS11820	COG1304	FMN binding
HAQ10_RS11825	COG1755	Isoprenylcysteine carboxyl methyltransferase
HAQ10_RS11850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAQ10_RS11860	COG3039	Transposase
HAQ10_RS11870	COG1136	(ABC) transporter
HAQ10_RS11915	COG3039	Transposase
HAQ10_RS11920	COG0513	Belongs to the DEAD box helicase family
HAQ10_RS12005	COG1858	cytochrome C peroxidase
HAQ10_RS12020	COG0702	epimerase
HAQ10_RS12045	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HAQ10_RS12070	COG2354	Protein conserved in bacteria
HAQ10_RS12075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HAQ10_RS12090	COG3264	Mechanosensitive ion channel
HAQ10_RS12090	COG1511	domain protein
HAQ10_RS12165	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HAQ10_RS12240	COG3039	Transposase
HAQ10_RS12250	COG3039	Transposase
HAQ10_RS12290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAQ10_RS12300	COG0642	Histidine kinase
HAQ10_RS12310	COG1090	epimerase
HAQ10_RS12320	COG3039	Transposase
HAQ10_RS12345	COG2826	transposase and inactivated derivatives, IS30 family
HAQ10_RS12410	COG1136	(ABC) transporter
HAQ10_RS12450	COG1272	protein, Hemolysin III
HAQ10_RS12455	COG1205	dead DEAH box helicase
HAQ10_RS12455	COG1111	helicase
HAQ10_RS12515	COG0070	glutamate synthase
HAQ10_RS12515	COG0069	glutamate synthase activity
HAQ10_RS12515	COG0067	glutamate synthase
HAQ10_RS12520	COG0493	'glutamate synthase
HAQ10_RS12570	COG1609	Transcriptional regulator
HAQ10_RS12600	COG0366	Alpha amylase catalytic
HAQ10_RS12605	COG0366	Alpha amylase catalytic
HAQ10_RS12650	COG0606	chelatase, subunit chli
HAQ10_RS12690	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HAQ10_RS12695	COG1166	arginine decarboxylase activity
HAQ10_RS12705	COG3501	Rhs element vgr protein
HAQ10_RS12780	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ10_RS12805	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HAQ10_RS12820	COG0210	DNA helicase
HAQ10_RS12835	COG3132	Protein of unknown function, DUF480
HAQ10_RS12840	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HAQ10_RS12845	COG0284	orotidine-5'-phosphate decarboxylase activity
HAQ10_RS12880	COG2937	Belongs to the GPAT DAPAT family
HAQ10_RS12920	COG3186	Phenylalanine-4-hydroxylase
HAQ10_RS12925	COG1522	sequence-specific DNA binding
HAQ10_RS12970	COG1064	alcohol dehydrogenase
HAQ10_RS12975	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HAQ10_RS12985	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HAQ10_RS12995	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HAQ10_RS13000	COG2826	transposase and inactivated derivatives, IS30 family
HAQ10_RS13025	COG3039	Transposase
HAQ10_RS13030	COG0676	glucose-6-phosphate 1-epimerase activity
HAQ10_RS13095	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HAQ10_RS13115	COG2853	Lipoprotein
HAQ10_RS13130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HAQ10_RS13135	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HAQ10_RS13140	COG1127	ABC transporter
HAQ10_RS13215	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAQ10_RS13225	COG3265	gluconokinase activity
HAQ10_RS13230	COG2211	Major facilitator Superfamily
HAQ10_RS13235	COG3459	Glycosyltransferase 36 associated
HAQ10_RS13245	COG2205	protein histidine kinase activity
HAQ10_RS13255	COG1414	Transcriptional regulator
HAQ10_RS13260	COG0738	Major facilitator superfamily
HAQ10_RS13265	COG3254	rhamnose metabolic process
HAQ10_RS13295	COG0339	signal peptide processing
HAQ10_RS13325	COG0564	pseudouridine synthase activity
HAQ10_RS13335	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HAQ10_RS13345	COG1181	Belongs to the D-alanine--D-alanine ligase family
HAQ10_RS13425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HAQ10_RS13435	COG0842	Transport permease protein
HAQ10_RS13440	COG1131	(ABC) transporter
HAQ10_RS13445	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HAQ10_RS13465	COG1476	TRANSCRIPTIONal
HAQ10_RS13475	COG4555	ABC transporter
HAQ10_RS13515	COG0625	glutathione transferase activity
HAQ10_RS13560	COG0583	DNA-binding transcription factor activity
HAQ10_RS13600	COG1199	ATP-dependent helicase activity
HAQ10_RS13620	COG1566	PFAM secretion protein HlyD family protein
HAQ10_RS13640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAQ10_RS13650	COG0745	RESPONSE REGULATOR receiver
HAQ10_RS13655	COG2205	protein histidine kinase activity
HAQ10_RS13680	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HAQ10_RS13680	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HAQ10_RS13685	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HAQ10_RS13700	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HAQ10_RS13735	COG3237	CsbD-like
HAQ10_RS13740	COG0180	Tryptophanyl-tRNA synthetase
HAQ10_RS13745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAQ10_RS13790	COG0753	catalase activity
HAQ10_RS13795	COG1595	DNA-templated transcription, initiation
HAQ10_RS13805	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HAQ10_RS13815	COG0628	permease
HAQ10_RS13825	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HAQ10_RS13830	COG1040	competence protein
HAQ10_RS13835	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HAQ10_RS13840	COG0156	8-amino-7-oxononanoate synthase activity
HAQ10_RS13850	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ10_RS13865	COG0463	Glycosyl transferase, family 2
HAQ10_RS13875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HAQ10_RS13880	COG3100	YcgL domain-containing protein
HAQ10_RS13895	COG3387	PFAM Glycoside hydrolase 15-related
HAQ10_RS13900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HAQ10_RS13915	COG2239	Acts as a magnesium transporter
HAQ10_RS13930	COG0045	succinate-CoA ligase (ADP-forming) activity
HAQ10_RS13930	COG1042	CoA-binding domain protein
HAQ10_RS13930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HAQ10_RS13940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAQ10_RS13945	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAQ10_RS13980	COG3485	protocatechuate 3,4-dioxygenase
HAQ10_RS13985	COG3485	protocatechuate 3,4-dioxygenase
HAQ10_RS14000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAQ10_RS14005	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HAQ10_RS14030	COG4221	oxidoreductase activity
HAQ10_RS14055	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HAQ10_RS14080	COG0463	Glycosyl transferase, family 2
HAQ10_RS14095	COG1475	DNA binding
HAQ10_RS14100	COG1192	Involved in chromosome partitioning
HAQ10_RS14115	COG0708	Exodeoxyribonuclease III
HAQ10_RS14120	COG2211	Major facilitator Superfamily
HAQ10_RS14135	COG0739	heme binding
HAQ10_RS14180	COG0745	RESPONSE REGULATOR receiver
HAQ10_RS14220	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HAQ10_RS14235	COG2814	Major facilitator Superfamily
HAQ10_RS14250	COG1289	transmembrane transporter activity
HAQ10_RS14260	COG1136	(ABC) transporter
HAQ10_RS14260	COG0577	efflux transmembrane transporter activity
HAQ10_RS14265	COG0151	Belongs to the GarS family
HAQ10_RS14275	COG0419	ATPase involved in DNA repair
HAQ10_RS14290	COG2267	carboxylic ester hydrolase activity
HAQ10_RS14295	COG2267	carboxylic ester hydrolase activity
HAQ10_RS14315	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HAQ10_RS14360	COG0439	Biotin carboxylase
HAQ10_RS14370	COG0511	ligase activity, forming carbon-carbon bonds
HAQ10_RS14375	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HAQ10_RS14385	COG1324	tolerance protein
HAQ10_RS14420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HAQ10_RS14440	COG0534	Mate efflux family protein
HAQ10_RS14445	COG0616	signal peptide processing
HAQ10_RS14455	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ10_RS14470	COG0009	L-threonylcarbamoyladenylate synthase
HAQ10_RS14475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HAQ10_RS14475	COG1754	DNA topoisomerase type I activity
HAQ10_RS14490	COG2922	Belongs to the Smg family
HAQ10_RS14495	COG0758	DNA mediated transformation
HAQ10_RS14500	COG1652	LysM domain
HAQ10_RS14505	COG0242	peptide deformylase activity
HAQ10_RS14510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HAQ10_RS14515	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HAQ10_RS14515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAQ10_RS14565	COG1560	Kdo2-lipid A biosynthetic process
HAQ10_RS14575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAQ10_RS14720	COG1294	oxidase, subunit
HAQ10_RS14725	COG1271	oxidase subunit
HAQ10_RS14735	COG2204	response regulator
HAQ10_RS14760	COG2972	Histidine kinase
HAQ10_RS14775	COG0531	amino acid
HAQ10_RS14795	COG3590	peptidase
HAQ10_RS14805	COG0667	Aldo Keto reductase
HAQ10_RS14820	COG3384	dioxygenase
HAQ10_RS14830	COG1573	uracil-dna glycosylase
HAQ10_RS14840	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HAQ10_RS14850	COG0025	NhaP-type Na H and K H
HAQ10_RS14855	COG1131	(ABC) transporter
HAQ10_RS14860	COG0842	Transport permease protein
HAQ10_RS14875	COG1404	Belongs to the peptidase S8 family
HAQ10_RS14890	COG0745	RESPONSE REGULATOR receiver
HAQ10_RS14940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAQ10_RS14965	COG2202	Pas domain
HAQ10_RS14965	COG2205	protein histidine kinase activity
HAQ10_RS14995	COG2813	Specifically methylates the guanine in position
HAQ10_RS15000	COG1187	pseudouridine synthase activity
HAQ10_RS15005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HAQ10_RS15040	COG0697	spore germination
HAQ10_RS15050	COG2011	ABC-type metal ion transport system permease component
HAQ10_RS15080	COG0508	dehydrogenase complex catalyzes the overall conversion of
HAQ10_RS15090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HAQ10_RS15110	COG0356	it plays a direct role in the translocation of protons across the membrane
HAQ10_RS15120	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HAQ10_RS15130	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HAQ10_RS15135	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HAQ10_RS15140	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HAQ10_RS15195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAQ10_RS15200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HAQ10_RS15255	COG0339	signal peptide processing
HAQ10_RS15290	COG1956	GAF domain-containing protein
HAQ10_RS15295	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HAQ10_RS15305	COG0720	synthase
HAQ10_RS15310	COG0513	Belongs to the DEAD box helicase family
HAQ10_RS15355	COG0626	cystathionine gamma-synthase activity
HAQ10_RS15395	COG3328	transposase activity
HAQ10_RS15420	COG2086	electron transfer activity
HAQ10_RS15445	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HAQ10_RS15445	COG0662	Cupin 2, conserved barrel domain protein
HAQ10_RS15450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAQ10_RS15485	COG3218	ABC-type transport auxiliary lipoprotein component
HAQ10_RS15485	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HAQ10_RS15490	COG1127	ABC transporter
HAQ10_RS15495	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HAQ10_RS15510	COG0442	prolyl-tRNA aminoacylation
HAQ10_RS15520	COG1183	phosphatidylcholine synthase activity
HAQ10_RS15545	COG3039	Transposase
HAQ10_RS15600	COG0525	valine-tRNA ligase activity
HAQ10_RS15615	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HAQ10_RS15625	COG0795	lipopolysaccharide-transporting ATPase activity
HAQ10_RS15635	COG4974	Belongs to the 'phage' integrase family
HAQ10_RS15640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HAQ10_RS15645	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAQ10_RS15645	COG0047	phosphoribosylformylglycinamidine synthase activity
HAQ10_RS15650	COG5295	Hep Hag repeat protein
HAQ10_RS15675	COG1404	Belongs to the peptidase S8 family
HAQ10_RS15680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HAQ10_RS15690	COG1459	type II secretion system
HAQ10_RS15695	COG2165	general secretion pathway protein
HAQ10_RS15700	COG4970	Tfp pilus assembly protein FimT
HAQ10_RS15705	COG2165	general secretion pathway protein
HAQ10_RS15710	COG4795	General secretion pathway protein
HAQ10_RS15715	COG3156	type II secretion system protein K
HAQ10_RS15720	COG3166	PFAM Fimbrial assembly family protein
HAQ10_RS15735	COG1450	Type ii and iii secretion system protein
HAQ10_RS15750	COG2188	Transcriptional regulator
HAQ10_RS15795	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HAQ10_RS15800	COG1518	maintenance of DNA repeat elements
HAQ10_RS15845	COG1399	metal-binding, possibly nucleic acid-binding protein
HAQ10_RS15870	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ10_RS15875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAQ10_RS15885	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HAQ10_RS15890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HAQ10_RS15925	COG3829	transcription factor binding
HAQ10_RS15960	COG3039	Transposase
HAQ10_RS16010	COG2826	transposase and inactivated derivatives, IS30 family
HAQ10_RS16020	COG0678	peroxiredoxin activity
HAQ10_RS16040	COG0330	HflC and HflK could
HAQ10_RS16045	COG0330	HflC and HflK could
HAQ10_RS16060	COG0308	aminopeptidase N
HAQ10_RS16105	COG1560	Kdo2-lipid A biosynthetic process
HAQ10_RS16110	COG1519	Transferase
HAQ10_RS16115	COG1538	Outer membrane efflux protein
HAQ10_RS16120	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HAQ10_RS16145	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAQ10_RS16150	COG0066	3-isopropylmalate dehydratase activity
HAQ10_RS16185	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HAQ10_RS16195	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HAQ10_RS16200	COG3710	Transcriptional regulator
HAQ10_RS16225	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HAQ10_RS16245	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HAQ10_RS16275	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HAQ10_RS16285	COG3781	membrane
HAQ10_RS16300	COG0625	glutathione transferase activity
HAQ10_RS16310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAQ10_RS16335	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HAQ10_RS16465	COG3039	Transposase
HAQ10_RS16485	COG0584	glycerophosphoryl diester phosphodiesterase
HAQ10_RS16510	COG0473	3-isopropylmalate dehydrogenase activity
HAQ10_RS16560	COG0544	peptidyl-prolyl cis-trans isomerase activity
HAQ10_RS16600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HAQ10_RS16625	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HAQ10_RS16635	COG0631	protein serine/threonine phosphatase activity
HAQ10_RS16660	COG3501	Rhs element vgr protein
HAQ10_RS16720	COG0582	viral genome integration into host DNA
HAQ10_RS16730	COG0859	PFAM glycosyl transferase family 9
HAQ10_RS16735	COG3642	lipopolysaccharide core region biosynthetic process
HAQ10_RS16740	COG1234	tRNA 3'-trailer cleavage
HAQ10_RS16745	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HAQ10_RS16755	COG0315	cyclic pyranopterin monophosphate synthase activity
HAQ10_RS16760	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HAQ10_RS16765	COG0314	molybdopterin synthase activity
HAQ10_RS16795	COG0537	adenosine 5'-monophosphoramidase activity
HAQ10_RS16815	COG0714	Associated with various cellular activities
HAQ10_RS16835	COG0242	peptide deformylase activity
HAQ10_RS16885	COG3039	Transposase
HAQ10_RS16910	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HAQ10_RS16915	COG0726	polysaccharide deacetylase
HAQ10_RS16965	COG2211	Major facilitator Superfamily
HAQ10_RS16975	COG1609	Transcriptional regulator
HAQ10_RS16980	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ10_RS16985	COG2851	Citrate transporter
HAQ10_RS17005	COG0642	Histidine kinase
HAQ10_RS17015	COG2197	response regulator
HAQ10_RS17030	COG0583	DNA-binding transcription factor activity
HAQ10_RS17045	COG4191	Histidine kinase
HAQ10_RS17065	COG0280	phosphate acetyltransferase
HAQ10_RS17065	COG0281	malic enzyme
HAQ10_RS17095	COG0352	thiamine-phosphate diphosphorylase activity
HAQ10_RS17100	COG1773	rubredoxin
HAQ10_RS17105	COG2912	Transglutaminase-like superfamily
HAQ10_RS17125	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HAQ10_RS17150	COG0006	proline dipeptidase activity
HAQ10_RS17190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HAQ10_RS17205	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HAQ10_RS17210	COG1561	YicC-like family, N-terminal region
HAQ10_RS17235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAQ10_RS17245	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HAQ10_RS17270	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HAQ10_RS17320	COG0714	Associated with various cellular activities
HAQ10_RS17340	COG2304	oxidoreductase activity
HAQ10_RS17360	COG1301	dicarboxylic acid transport
HAQ10_RS17365	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HAQ10_RS17375	COG0739	heme binding
HAQ10_RS17380	COG1376	ErfK ybiS ycfS ynhG family protein
HAQ10_RS17405	COG1022	Amp-dependent synthetase and ligase
HAQ10_RS17415	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ10_RS17425	COG0745	RESPONSE REGULATOR receiver
HAQ10_RS17430	COG0642	Histidine kinase
HAQ10_RS17450	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HAQ10_RS17455	COG4149	molybdate abc transporter
HAQ10_RS17460	COG0725	ABC transporter, periplasmic molybdate-binding protein
HAQ10_RS17465	COG3453	Protein conserved in bacteria
HAQ10_RS17465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAQ10_RS17495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HAQ10_RS17515	COG2205	protein histidine kinase activity
HAQ10_RS17520	COG0745	RESPONSE REGULATOR receiver
HAQ10_RS17570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HAQ10_RS17575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HAQ10_RS17650	COG2801	Transposase and inactivated derivatives
HAQ10_RS17690	COG2201	protein-glutamate methylesterase activity
HAQ10_RS17735	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HAQ10_RS17750	COG1842	Phage shock protein A
HAQ10_RS17775	COG0754	glutathionylspermidine amidase activity
HAQ10_RS17840	COG0531	amino acid
HAQ10_RS17845	COG2197	response regulator
HAQ10_RS17860	COG1113	amino acid transport
HAQ10_RS17875	COG1271	oxidase subunit
HAQ10_RS17880	COG1294	oxidase, subunit
HAQ10_RS17890	COG2239	Acts as a magnesium transporter
HAQ10_RS17895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAQ10_RS17900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HAQ10_RS17910	COG1660	Displays ATPase and GTPase activities
HAQ10_RS17915	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HAQ10_RS17920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HAQ10_RS17935	COG1137	ATPase activity
HAQ10_RS17940	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HAQ10_RS17950	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HAQ10_RS17960	COG0271	Belongs to the BolA IbaG family
HAQ10_RS17965	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAQ10_RS17985	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HAQ10_RS18000	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HAQ10_RS18010	COG0628	permease
HAQ10_RS18020	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HAQ10_RS18025	COG3178	'Phosphotransferase
HAQ10_RS18040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HAQ10_RS18045	COG1555	photosystem II stabilization
HAQ10_RS18090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HAQ10_RS18100	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HAQ10_RS18120	COG0228	four-way junction DNA binding
HAQ10_RS18125	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HAQ10_RS18130	COG0336	Belongs to the RNA methyltransferase TrmD family
HAQ10_RS18145	COG0534	Mate efflux family protein
HAQ10_RS18180	COG0542	response to heat
HAQ10_RS18215	COG4206	TonB-dependent receptor
HAQ10_RS18275	COG0019	diaminopimelate decarboxylase activity
HAQ10_RS18285	COG2814	Major facilitator Superfamily
HAQ10_RS18290	COG4264	IucA IucC family
HAQ10_RS18300	COG4772	TonB-dependent receptor
HAQ10_RS18315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HAQ10_RS18315	COG4651	solute:proton antiporter activity
HAQ10_RS18350	COG0488	(ABC) transporter
HAQ10_RS18375	COG2755	lipolytic protein G-D-S-L family
HAQ10_RS18375	COG0657	acetylesterase activity
HAQ10_RS18405	COG2207	Transcriptional regulator
HAQ10_RS18410	COG0326	Molecular chaperone. Has ATPase activity
HAQ10_RS18435	COG3328	transposase activity
HAQ10_RS18440	COG0174	glutamine synthetase
HAQ10_RS18445	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
HAQ10_RS18455	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HAQ10_RS18470	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HAQ10_RS18505	COG2146	nitrite reductase [NAD(P)H] activity
HAQ10_RS18515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HAQ10_RS18520	COG0719	Fe-S assembly protein
HAQ10_RS18525	COG0396	ATPase activity
HAQ10_RS18530	COG0719	Fe-S assembly protein
HAQ10_RS18535	COG1959	2 iron, 2 sulfur cluster binding
HAQ10_RS18555	COG0693	protein deglycase activity
HAQ10_RS18595	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HAQ10_RS18625	COG0519	Catalyzes the synthesis of GMP from XMP
HAQ10_RS18635	COG1678	Uncharacterized ACR, COG1678
HAQ10_RS18640	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HAQ10_RS18655	COG1764	response to oxidative stress
HAQ10_RS18665	COG0384	phenazine biosynthesis protein PhzF
HAQ10_RS18675	COG0527	aspartate kinase activity
HAQ10_RS18700	COG0142	geranyltranstransferase activity
HAQ10_RS18705	COG0629	single-stranded DNA binding
HAQ10_RS18710	COG2203	Gaf domain
HAQ10_RS18710	COG3706	GGDEF domain
HAQ10_RS18710	COG5001	Diguanylate cyclase
HAQ10_RS18710	COG4251	negative regulation of phosphorylation
HAQ10_RS18745	COG2879	small protein
HAQ10_RS18750	COG1966	Carbon starvation protein
HAQ10_RS18755	COG1741	Belongs to the pirin family
HAQ10_RS18765	COG3501	Rhs element vgr protein
HAQ10_RS18785	COG3039	Transposase
HAQ10_RS18795	COG3501	Rhs element vgr protein
HAQ10_RS18825	COG3501	Rhs element vgr protein
HAQ10_RS18885	COG1741	Belongs to the pirin family
HAQ10_RS18890	COG1515	deoxyribonuclease V activity
HAQ10_RS18910	COG3590	peptidase
HAQ10_RS18925	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HAQ10_RS18930	COG2199	diguanylate cyclase activity
HAQ10_RS18930	COG2200	EAL domain
HAQ10_RS18930	COG2202	Pas domain
HAQ10_RS18935	COG0835	chemotaxis
HAQ10_RS18940	COG0840	transmembrane signaling receptor activity
HAQ10_RS18945	COG2198	Histidine kinase
HAQ10_RS18945	COG0643	Histidine kinase
HAQ10_RS18960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HAQ10_RS18970	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HAQ10_RS18985	COG2205	protein histidine kinase activity
HAQ10_RS19010	COG3039	Transposase
HAQ10_RS19035	COG3039	Transposase
HAQ10_RS19070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HAQ10_RS19075	COG0735	belongs to the Fur family
HAQ10_RS19135	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HAQ10_RS19140	COG0084	hydrolase, TatD family'
HAQ10_RS19155	COG1960	acyl-CoA dehydrogenase activity
HAQ10_RS19170	COG0367	asparagine synthase
HAQ10_RS19180	COG0305	Participates in initiation and elongation during chromosome replication
HAQ10_RS19185	COG0415	Belongs to the DNA photolyase family
HAQ10_RS19200	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ10_RS19245	COG3039	Transposase
HAQ10_RS19305	COG5002	protein histidine kinase activity
HAQ10_RS19305	COG5001	Diguanylate cyclase
HAQ10_RS19310	COG1187	pseudouridine synthase activity
HAQ10_RS19330	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HAQ10_RS19340	COG0475	glutathione-regulated potassium exporter activity
HAQ10_RS19345	COG5002	protein histidine kinase activity
HAQ10_RS19345	COG5000	phosphorelay sensor kinase activity
HAQ10_RS19350	COG0745	RESPONSE REGULATOR receiver
HAQ10_RS19380	COG1132	(ABC) transporter
HAQ10_RS19410	COG3039	Transposase
HAQ10_RS19435	COG3039	Transposase
HAQ10_RS19470	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HAQ10_RS19480	COG4969	Belongs to the N-Me-Phe pilin family
HAQ10_RS19485	COG2194	sulfuric ester hydrolase activity
HAQ10_RS19525	COG0045	succinate-CoA ligase (ADP-forming) activity
HAQ10_RS19530	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HAQ10_RS19545	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HAQ10_RS19545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HAQ10_RS19550	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAQ10_RS19555	COG0564	pseudouridine synthase activity
HAQ10_RS19580	COG3387	PFAM Glycoside hydrolase 15-related
HAQ10_RS19585	COG1877	trehalose-phosphatase activity
HAQ10_RS19625	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
HAQ10_RS19645	COG1595	DNA-templated transcription, initiation
HAQ10_RS19655	COG1946	Acyl-CoA thioesterase
HAQ10_RS19670	COG0824	Thioesterase
HAQ10_RS19675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HAQ10_RS19685	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HAQ10_RS19690	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HAQ10_RS19695	COG0268	Binds directly to 16S ribosomal RNA
HAQ10_RS19700	COG0728	peptidoglycan biosynthetic process
HAQ10_RS19705	COG0196	riboflavin kinase activity
HAQ10_RS19715	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HAQ10_RS19720	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HAQ10_RS19735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HAQ10_RS19740	COG1845	cytochrome c oxidase, subunit III
HAQ10_RS19745	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HAQ10_RS19755	COG3501	Rhs element vgr protein
HAQ10_RS19765	COG3209	COG3209 Rhs family protein
HAQ10_RS19765	COG3209	COG3209 Rhs family protein
HAQ10_RS19870	COG0632	four-way junction helicase activity
HAQ10_RS19880	COG2255	four-way junction helicase activity
HAQ10_RS19885	COG0824	Thioesterase
HAQ10_RS19895	COG0848	biopolymer transport protein
HAQ10_RS19910	COG2885	chlorophyll binding
HAQ10_RS19920	COG0602	queuosine metabolic process
HAQ10_RS19925	COG1187	pseudouridine synthase activity
HAQ10_RS19940	COG0840	transmembrane signaling receptor activity
HAQ10_RS19985	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HAQ10_RS20160	COG3179	chitinase
HAQ10_RS20205	COG4695	Portal protein
HAQ10_RS20245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HAQ10_RS20265	COG0514	ATP-dependent DNA helicase (RecQ)
HAQ10_RS20270	COG0783	Belongs to the Dps family
HAQ10_RS20275	COG1643	Atp-dependent helicase
HAQ10_RS20330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAQ10_RS20340	COG1215	transferase activity, transferring glycosyl groups
HAQ10_RS20345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HAQ10_RS20355	COG1199	ATP-dependent helicase activity
HAQ10_RS20365	COG1397	ADP-ribosylglycohydrolase
HAQ10_RS20375	COG0189	ligase activity
HAQ10_RS20390	COG0835	chemotaxis
HAQ10_RS20395	COG0840	transmembrane signaling receptor activity
HAQ10_RS20400	COG0643	Histidine kinase
HAQ10_RS20400	COG2198	Histidine kinase
HAQ10_RS20400	COG0784	Response regulator, receiver
HAQ10_RS20435	COG1446	asparaginase
HAQ10_RS20440	COG3142	Participates in the control of copper homeostasis
HAQ10_RS20490	COG3537	Alpha-1,2-mannosidase
HAQ10_RS20565	COG1472	Belongs to the glycosyl hydrolase 3 family
HAQ10_RS20575	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HAQ10_RS20585	COG1388	LysM domain
HAQ10_RS20585	COG3858	chitin binding
HAQ10_RS20600	COG0837	glucose binding
HAQ10_RS20605	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HAQ10_RS20615	COG0494	nUDIX hydrolase
HAQ10_RS20625	COG3956	TIGRFAM MazG family protein
HAQ10_RS20640	COG0330	HflC and HflK could
HAQ10_RS20655	COG0509	glycine decarboxylation via glycine cleavage system
HAQ10_RS20690	COG1960	acyl-CoA dehydrogenase activity
HAQ10_RS20700	COG1309	transcriptional regulator
HAQ10_RS20705	COG4771	TonB-dependent receptor
HAQ10_RS20715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HAQ10_RS20725	COG0463	Glycosyl transferase, family 2
HAQ10_RS20745	COG1272	protein, Hemolysin III
HAQ10_RS20755	COG0739	heme binding
HAQ10_RS20760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAQ10_RS20765	COG0626	cystathionine gamma-synthase activity
HAQ10_RS20775	COG1760	l-serine dehydratase
HAQ10_RS20790	COG2353	YceI-like domain
HAQ10_RS20800	COG2353	YceI-like domain
HAQ10_RS20850	COG3867	Arabinogalactan endo-beta-1,4-galactanase
HAQ10_RS20870	COG1960	acyl-CoA dehydrogenase activity
HAQ10_RS20875	COG1024	Enoyl-CoA hydratase
HAQ10_RS20895	COG1024	Enoyl-CoA hydratase
HAQ10_RS20895	COG1250	3-hydroxyacyl-CoA dehydrogenase
HAQ10_RS20910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAQ10_RS20940	COG1381	Involved in DNA repair and RecF pathway recombination
HAQ10_RS20955	COG2954	triphosphatase activity
HAQ10_RS20970	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HAQ10_RS20975	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
HAQ10_RS20980	COG3046	protein related to deoxyribodipyrimidine photolyase
HAQ10_RS20995	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HAQ10_RS21000	COG1278	Cold shock
HAQ10_RS21020	COG1201	RNA secondary structure unwinding
HAQ10_RS21025	COG1793	dna ligase
HAQ10_RS21035	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HAQ10_RS21035	COG1793	dna ligase
HAQ10_RS21065	COG0183	Belongs to the thiolase family
HAQ10_RS21085	COG1451	nucleotide metabolic process
HAQ10_RS21100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HAQ10_RS21135	COG1047	Peptidyl-prolyl cis-trans
HAQ10_RS21150	COG2824	Alkylphosphonate utilization operon protein PhnA
HAQ10_RS21160	COG1902	pentaerythritol trinitrate reductase activity
HAQ10_RS21165	COG2814	Major facilitator Superfamily
HAQ10_RS21210	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HAQ10_RS21210	COG0392	lysyltransferase activity
HAQ10_RS21220	COG0251	oxidation-reduction process
HAQ10_RS21225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HAQ10_RS21240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HAQ10_RS21265	COG1595	DNA-templated transcription, initiation
HAQ10_RS21280	COG2878	Part of a membrane complex involved in electron transport
HAQ10_RS21290	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAQ10_RS21290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAQ10_RS21310	COG0833	amino acid
HAQ10_RS21315	COG2040	homocysteine
HAQ10_RS21330	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HAQ10_RS21365	COG0529	Catalyzes the synthesis of activated sulfate
HAQ10_RS21365	COG2895	sulfate adenylyltransferase (ATP) activity
HAQ10_RS21435	COG1131	(ABC) transporter
HAQ10_RS21440	COG4771	TonB-dependent receptor
HAQ10_RS21450	COG0825	malonyl-CoA metabolic process
HAQ10_RS21470	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HAQ10_RS21475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HAQ10_RS21490	COG0750	zinc metalloprotease
HAQ10_RS21500	COG0575	Belongs to the CDS family
HAQ10_RS21510	COG0233	cytoplasmic translational termination
HAQ10_RS21525	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HAQ10_RS21585	COG1393	Belongs to the ArsC family
HAQ10_RS21600	COG0367	asparagine synthase
HAQ10_RS21610	COG4774	siderophore transport
HAQ10_RS21645	COG1566	PFAM secretion protein HlyD family protein
HAQ10_RS21650	COG2814	Major facilitator Superfamily
HAQ10_RS21695	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HAQ10_RS21705	COG1960	acyl-CoA dehydrogenase activity
HAQ10_RS21730	COG2914	Belongs to the UPF0125 (RnfH) family
HAQ10_RS21735	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAQ10_RS21745	COG0497	DNA recombination
HAQ10_RS21755	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HAQ10_RS21760	COG0443	Heat shock 70 kDa protein
HAQ10_RS21765	COG0484	heat shock protein binding
HAQ10_RS21770	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HAQ10_RS21775	COG1605	Chorismate mutase
HAQ10_RS21775	COG0287	Prephenate dehydrogenase
HAQ10_RS21790	COG0583	DNA-binding transcription factor activity
HAQ10_RS21805	COG1132	(ABC) transporter
HAQ10_RS21840	COG2850	peptidyl-arginine hydroxylation
HAQ10_RS21920	COG1131	(ABC) transporter
HAQ10_RS21925	COG1725	Transcriptional regulator
HAQ10_RS21935	COG0386	Belongs to the glutathione peroxidase family
HAQ10_RS21950	COG2900	Belongs to the SlyX family
HAQ10_RS21975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAQ10_RS21985	COG1410	methionine synthase
HAQ10_RS21985	COG0646	methionine synthase
HAQ10_RS21990	COG1410	methionine synthase
HAQ10_RS21990	COG0646	methionine synthase
HAQ10_RS21995	COG2226	methyltransferase
HAQ10_RS22000	COG1960	acyl-CoA dehydrogenase activity
HAQ10_RS22025	COG0557	exoribonuclease II activity
HAQ10_RS22045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAQ10_RS22055	COG3039	Transposase
HAQ10_RS22075	COG3328	transposase activity
HAQ10_RS22085	COG1278	Cold shock
HAQ10_RS22100	COG3039	Transposase
HAQ10_RS22150	COG3039	Transposase
HAQ10_RS22200	COG3039	Transposase
HAQ10_RS22210	COG0583	DNA-binding transcription factor activity
HAQ10_RS22285	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HAQ10_RS22295	COG0531	amino acid
HAQ10_RS22300	COG0531	amino acid
HAQ10_RS22310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HAQ10_RS22315	COG0277	FAD linked oxidase domain protein
HAQ10_RS22380	COG0436	Aminotransferase
HAQ10_RS22405	COG1187	pseudouridine synthase activity
HAQ10_RS22410	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HAQ10_RS22415	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HAQ10_RS22420	COG2350	Protein conserved in bacteria
HAQ10_RS22450	COG1175	transmembrane transport
HAQ10_RS22455	COG0395	ABC-type sugar transport system, permease component
HAQ10_RS22480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HAQ10_RS22490	COG2957	Belongs to the agmatine deiminase family
HAQ10_RS22505	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HAQ10_RS22510	COG0539	negative regulation of cytoplasmic translation
HAQ10_RS22515	COG0776	regulation of translation
HAQ10_RS22525	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HAQ10_RS22530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HAQ10_RS22540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HAQ10_RS22560	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HAQ10_RS22575	COG3002	Belongs to the UPF0753 family
HAQ10_RS22580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HAQ10_RS22585	COG0583	DNA-binding transcription factor activity
HAQ10_RS22615	COG0583	DNA-binding transcription factor activity
HAQ10_RS22635	COG1914	H( )-stimulated, divalent metal cation uptake system
HAQ10_RS22655	COG0668	transmembrane transport
HAQ10_RS22680	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ10_RS22685	COG1183	phosphatidylcholine synthase activity
HAQ10_RS22695	COG3243	poly(R)-hydroxyalkanoic acid synthase
HAQ10_RS22710	COG0723	plastoquinol--plastocyanin reductase activity
HAQ10_RS22710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAQ10_RS22720	COG2183	response to ionizing radiation
HAQ10_RS22735	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HAQ10_RS22750	COG0671	phosphoesterase, PA-phosphatase related
HAQ10_RS22775	COG1794	racemase activity, acting on amino acids and derivatives
HAQ10_RS22780	COG0697	spore germination
HAQ10_RS22810	COG1012	belongs to the aldehyde dehydrogenase family
HAQ10_RS22845	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HAQ10_RS22860	COG0124	histidyl-tRNA synthetase
HAQ10_RS22880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HAQ10_RS22895	COG0131	Imidazoleglycerol-phosphate dehydratase
HAQ10_RS22895	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HAQ10_RS22905	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HAQ10_RS22915	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HAQ10_RS22915	COG0140	phosphoribosyl-ATP diphosphatase activity
HAQ10_RS22950	COG0653	protein targeting
HAQ10_RS23105	COG3039	Transposase
HAQ10_RS23155	COG2201	protein-glutamate methylesterase activity
HAQ10_RS23165	COG2801	Transposase and inactivated derivatives
HAQ10_RS23185	COG3039	Transposase
HAQ10_RS23205	COG3328	transposase activity
HAQ10_RS23240	COG0322	excinuclease ABC activity
HAQ10_RS23250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HAQ10_RS23260	COG1663	tetraacyldisaccharide 4'-kinase activity
HAQ10_RS23275	COG0811	peptide transport
HAQ10_RS23300	COG4591	ABC-type transport system involved in lipoprotein release permease component
HAQ10_RS23315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HAQ10_RS23330	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HAQ10_RS23345	COG0354	folic acid binding
HAQ10_RS23360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HAQ10_RS23370	COG0363	glucosamine-6-phosphate deaminase activity
HAQ10_RS23375	COG0129	dihydroxy-acid dehydratase activity
HAQ10_RS23380	COG0800	Aldolase