locus-tag	class	description
HAQ11_RS00010	COG2040	homocysteine
HAQ11_RS00015	COG0833	amino acid
HAQ11_RS00035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAQ11_RS00035	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAQ11_RS00045	COG2878	Part of a membrane complex involved in electron transport
HAQ11_RS00060	COG1595	DNA-templated transcription, initiation
HAQ11_RS00085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HAQ11_RS00100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HAQ11_RS00105	COG0251	oxidation-reduction process
HAQ11_RS00115	COG0392	lysyltransferase activity
HAQ11_RS00115	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HAQ11_RS00160	COG2814	Major facilitator Superfamily
HAQ11_RS00165	COG1902	pentaerythritol trinitrate reductase activity
HAQ11_RS00175	COG2824	Alkylphosphonate utilization operon protein PhnA
HAQ11_RS00190	COG1047	Peptidyl-prolyl cis-trans
HAQ11_RS00225	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HAQ11_RS00240	COG1451	nucleotide metabolic process
HAQ11_RS00260	COG0183	Belongs to the thiolase family
HAQ11_RS00290	COG1793	dna ligase
HAQ11_RS00290	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HAQ11_RS00300	COG1793	dna ligase
HAQ11_RS00305	COG1201	RNA secondary structure unwinding
HAQ11_RS00325	COG1278	Cold shock
HAQ11_RS00330	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HAQ11_RS00345	COG3046	protein related to deoxyribodipyrimidine photolyase
HAQ11_RS00350	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
HAQ11_RS00355	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HAQ11_RS00370	COG2954	triphosphatase activity
HAQ11_RS00385	COG1381	Involved in DNA repair and RecF pathway recombination
HAQ11_RS00415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAQ11_RS00430	COG1250	3-hydroxyacyl-CoA dehydrogenase
HAQ11_RS00430	COG1024	Enoyl-CoA hydratase
HAQ11_RS00450	COG1024	Enoyl-CoA hydratase
HAQ11_RS00455	COG1960	acyl-CoA dehydrogenase activity
HAQ11_RS00475	COG3867	Arabinogalactan endo-beta-1,4-galactanase
HAQ11_RS00525	COG2353	YceI-like domain
HAQ11_RS00535	COG2353	YceI-like domain
HAQ11_RS00550	COG1760	l-serine dehydratase
HAQ11_RS00560	COG0626	cystathionine gamma-synthase activity
HAQ11_RS00565	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAQ11_RS00570	COG0739	heme binding
HAQ11_RS00580	COG1272	protein, Hemolysin III
HAQ11_RS00600	COG0463	Glycosyl transferase, family 2
HAQ11_RS00610	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HAQ11_RS00620	COG4771	TonB-dependent receptor
HAQ11_RS00625	COG1309	transcriptional regulator
HAQ11_RS00635	COG1960	acyl-CoA dehydrogenase activity
HAQ11_RS00670	COG0509	glycine decarboxylation via glycine cleavage system
HAQ11_RS00685	COG0330	HflC and HflK could
HAQ11_RS00700	COG3956	TIGRFAM MazG family protein
HAQ11_RS00710	COG0494	nUDIX hydrolase
HAQ11_RS00720	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HAQ11_RS00725	COG0837	glucose binding
HAQ11_RS00740	COG1388	LysM domain
HAQ11_RS00740	COG3858	chitin binding
HAQ11_RS00750	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HAQ11_RS00760	COG1472	Belongs to the glycosyl hydrolase 3 family
HAQ11_RS00835	COG3537	Alpha-1,2-mannosidase
HAQ11_RS00885	COG3142	Participates in the control of copper homeostasis
HAQ11_RS00890	COG1446	asparaginase
HAQ11_RS00925	COG2198	Histidine kinase
HAQ11_RS00925	COG0784	Response regulator, receiver
HAQ11_RS00925	COG0643	Histidine kinase
HAQ11_RS00930	COG0840	transmembrane signaling receptor activity
HAQ11_RS00935	COG0835	chemotaxis
HAQ11_RS00950	COG0189	ligase activity
HAQ11_RS00960	COG1397	ADP-ribosylglycohydrolase
HAQ11_RS00970	COG1199	ATP-dependent helicase activity
HAQ11_RS00980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HAQ11_RS00985	COG1215	transferase activity, transferring glycosyl groups
HAQ11_RS00995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAQ11_RS01050	COG1643	Atp-dependent helicase
HAQ11_RS01055	COG0783	Belongs to the Dps family
HAQ11_RS01060	COG0514	ATP-dependent DNA helicase (RecQ)
HAQ11_RS01080	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HAQ11_RS01135	COG1187	pseudouridine synthase activity
HAQ11_RS01140	COG0602	queuosine metabolic process
HAQ11_RS01150	COG2885	chlorophyll binding
HAQ11_RS01165	COG0848	biopolymer transport protein
HAQ11_RS01175	COG0824	Thioesterase
HAQ11_RS01180	COG2255	four-way junction helicase activity
HAQ11_RS01190	COG0632	four-way junction helicase activity
HAQ11_RS01295	COG3209	COG3209 Rhs family protein
HAQ11_RS01295	COG3209	COG3209 Rhs family protein
HAQ11_RS01305	COG3501	Rhs element vgr protein
HAQ11_RS01315	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HAQ11_RS01320	COG1845	cytochrome c oxidase, subunit III
HAQ11_RS01325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HAQ11_RS01340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HAQ11_RS01345	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HAQ11_RS01355	COG0196	riboflavin kinase activity
HAQ11_RS01360	COG0728	peptidoglycan biosynthetic process
HAQ11_RS01365	COG0268	Binds directly to 16S ribosomal RNA
HAQ11_RS01370	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HAQ11_RS01375	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HAQ11_RS01385	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HAQ11_RS01390	COG0824	Thioesterase
HAQ11_RS01405	COG1946	Acyl-CoA thioesterase
HAQ11_RS01415	COG1595	DNA-templated transcription, initiation
HAQ11_RS01435	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
HAQ11_RS01475	COG1877	trehalose-phosphatase activity
HAQ11_RS01480	COG3387	PFAM Glycoside hydrolase 15-related
HAQ11_RS01505	COG0564	pseudouridine synthase activity
HAQ11_RS01510	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAQ11_RS01515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HAQ11_RS01515	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HAQ11_RS01530	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HAQ11_RS01535	COG0045	succinate-CoA ligase (ADP-forming) activity
HAQ11_RS01575	COG2194	sulfuric ester hydrolase activity
HAQ11_RS01580	COG4969	Belongs to the N-Me-Phe pilin family
HAQ11_RS01590	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HAQ11_RS01625	COG3039	Transposase
HAQ11_RS01650	COG3039	Transposase
HAQ11_RS01680	COG1132	(ABC) transporter
HAQ11_RS01710	COG0745	RESPONSE REGULATOR receiver
HAQ11_RS01715	COG5000	phosphorelay sensor kinase activity
HAQ11_RS01715	COG5002	protein histidine kinase activity
HAQ11_RS01720	COG0475	glutathione-regulated potassium exporter activity
HAQ11_RS01730	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HAQ11_RS01750	COG1187	pseudouridine synthase activity
HAQ11_RS01755	COG5001	Diguanylate cyclase
HAQ11_RS01755	COG5002	protein histidine kinase activity
HAQ11_RS01815	COG3039	Transposase
HAQ11_RS01860	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ11_RS01875	COG0415	Belongs to the DNA photolyase family
HAQ11_RS01880	COG0305	Participates in initiation and elongation during chromosome replication
HAQ11_RS01890	COG0367	asparagine synthase
HAQ11_RS01905	COG1960	acyl-CoA dehydrogenase activity
HAQ11_RS01920	COG0084	hydrolase, TatD family'
HAQ11_RS01925	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HAQ11_RS01985	COG0735	belongs to the Fur family
HAQ11_RS01990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HAQ11_RS02025	COG3039	Transposase
HAQ11_RS02050	COG3039	Transposase
HAQ11_RS02070	COG3039	Transposase
HAQ11_RS02085	COG2205	protein histidine kinase activity
HAQ11_RS02100	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HAQ11_RS02110	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HAQ11_RS02125	COG0643	Histidine kinase
HAQ11_RS02125	COG2198	Histidine kinase
HAQ11_RS02130	COG0840	transmembrane signaling receptor activity
HAQ11_RS02135	COG0835	chemotaxis
HAQ11_RS02140	COG2199	diguanylate cyclase activity
HAQ11_RS02140	COG2200	EAL domain
HAQ11_RS02140	COG2202	Pas domain
HAQ11_RS02145	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HAQ11_RS02160	COG3590	peptidase
HAQ11_RS02180	COG1515	deoxyribonuclease V activity
HAQ11_RS02190	COG1741	Belongs to the pirin family
HAQ11_RS02250	COG3501	Rhs element vgr protein
HAQ11_RS02280	COG3501	Rhs element vgr protein
HAQ11_RS02300	COG3501	Rhs element vgr protein
HAQ11_RS02310	COG1741	Belongs to the pirin family
HAQ11_RS02315	COG1966	Carbon starvation protein
HAQ11_RS02320	COG2879	small protein
HAQ11_RS02355	COG4251	negative regulation of phosphorylation
HAQ11_RS02355	COG3706	GGDEF domain
HAQ11_RS02355	COG2203	Gaf domain
HAQ11_RS02355	COG5001	Diguanylate cyclase
HAQ11_RS02360	COG0629	single-stranded DNA binding
HAQ11_RS02365	COG0142	geranyltranstransferase activity
HAQ11_RS02390	COG0527	aspartate kinase activity
HAQ11_RS02400	COG0384	phenazine biosynthesis protein PhzF
HAQ11_RS02410	COG1764	response to oxidative stress
HAQ11_RS02425	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HAQ11_RS02430	COG1678	Uncharacterized ACR, COG1678
HAQ11_RS02440	COG0519	Catalyzes the synthesis of GMP from XMP
HAQ11_RS02470	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HAQ11_RS02510	COG0693	protein deglycase activity
HAQ11_RS02530	COG1959	2 iron, 2 sulfur cluster binding
HAQ11_RS02535	COG0719	Fe-S assembly protein
HAQ11_RS02540	COG0396	ATPase activity
HAQ11_RS02545	COG0719	Fe-S assembly protein
HAQ11_RS02550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HAQ11_RS02565	COG2146	nitrite reductase [NAD(P)H] activity
HAQ11_RS02600	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HAQ11_RS02615	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HAQ11_RS02625	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
HAQ11_RS02630	COG0174	glutamine synthetase
HAQ11_RS02635	COG3328	transposase activity
HAQ11_RS02660	COG0326	Molecular chaperone. Has ATPase activity
HAQ11_RS02665	COG2207	Transcriptional regulator
HAQ11_RS02695	COG0657	acetylesterase activity
HAQ11_RS02695	COG2755	lipolytic protein G-D-S-L family
HAQ11_RS02720	COG0488	(ABC) transporter
HAQ11_RS02755	COG4651	solute:proton antiporter activity
HAQ11_RS02755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HAQ11_RS02770	COG4772	TonB-dependent receptor
HAQ11_RS02780	COG4264	IucA IucC family
HAQ11_RS02785	COG2814	Major facilitator Superfamily
HAQ11_RS02795	COG0019	diaminopimelate decarboxylase activity
HAQ11_RS02855	COG4206	TonB-dependent receptor
HAQ11_RS02890	COG0542	response to heat
HAQ11_RS02925	COG0534	Mate efflux family protein
HAQ11_RS02940	COG0336	Belongs to the RNA methyltransferase TrmD family
HAQ11_RS02945	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HAQ11_RS02950	COG0228	four-way junction DNA binding
HAQ11_RS02970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HAQ11_RS02980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HAQ11_RS03025	COG1555	photosystem II stabilization
HAQ11_RS03030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HAQ11_RS03045	COG3178	'Phosphotransferase
HAQ11_RS03050	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HAQ11_RS03060	COG0628	permease
HAQ11_RS03070	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HAQ11_RS03085	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HAQ11_RS03105	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAQ11_RS03110	COG0271	Belongs to the BolA IbaG family
HAQ11_RS03120	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HAQ11_RS03130	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HAQ11_RS03135	COG1137	ATPase activity
HAQ11_RS03150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HAQ11_RS03155	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HAQ11_RS03160	COG1660	Displays ATPase and GTPase activities
HAQ11_RS03175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HAQ11_RS03180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAQ11_RS03185	COG2239	Acts as a magnesium transporter
HAQ11_RS03195	COG1294	oxidase, subunit
HAQ11_RS03200	COG1271	oxidase subunit
HAQ11_RS03215	COG1113	amino acid transport
HAQ11_RS03230	COG2197	response regulator
HAQ11_RS03235	COG0531	amino acid
HAQ11_RS03295	COG0754	glutathionylspermidine amidase activity
HAQ11_RS03320	COG1842	Phage shock protein A
HAQ11_RS03335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HAQ11_RS03380	COG2201	protein-glutamate methylesterase activity
HAQ11_RS03470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HAQ11_RS03475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HAQ11_RS03515	COG0745	RESPONSE REGULATOR receiver
HAQ11_RS03520	COG2205	protein histidine kinase activity
HAQ11_RS03540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HAQ11_RS03570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAQ11_RS03570	COG3453	Protein conserved in bacteria
HAQ11_RS03575	COG0725	ABC transporter, periplasmic molybdate-binding protein
HAQ11_RS03580	COG4149	molybdate abc transporter
HAQ11_RS03585	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HAQ11_RS03605	COG0642	Histidine kinase
HAQ11_RS03610	COG0745	RESPONSE REGULATOR receiver
HAQ11_RS03620	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ11_RS03630	COG1022	Amp-dependent synthetase and ligase
HAQ11_RS03655	COG1376	ErfK ybiS ycfS ynhG family protein
HAQ11_RS03660	COG0739	heme binding
HAQ11_RS03670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HAQ11_RS03675	COG1301	dicarboxylic acid transport
HAQ11_RS03695	COG2304	oxidoreductase activity
HAQ11_RS03715	COG0714	Associated with various cellular activities
HAQ11_RS03765	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HAQ11_RS03790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HAQ11_RS03800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAQ11_RS03825	COG1561	YicC-like family, N-terminal region
HAQ11_RS03830	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HAQ11_RS03845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HAQ11_RS03885	COG0006	proline dipeptidase activity
HAQ11_RS03910	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HAQ11_RS03930	COG2912	Transglutaminase-like superfamily
HAQ11_RS03935	COG1773	rubredoxin
HAQ11_RS03940	COG0352	thiamine-phosphate diphosphorylase activity
HAQ11_RS03965	COG0281	malic enzyme
HAQ11_RS03965	COG0280	phosphate acetyltransferase
HAQ11_RS03985	COG4191	Histidine kinase
HAQ11_RS04000	COG0583	DNA-binding transcription factor activity
HAQ11_RS04015	COG2197	response regulator
HAQ11_RS04025	COG0642	Histidine kinase
HAQ11_RS04045	COG2851	Citrate transporter
HAQ11_RS04050	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ11_RS04055	COG1609	Transcriptional regulator
HAQ11_RS04065	COG2211	Major facilitator Superfamily
HAQ11_RS04115	COG0726	polysaccharide deacetylase
HAQ11_RS04120	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HAQ11_RS04145	COG3039	Transposase
HAQ11_RS04195	COG0242	peptide deformylase activity
HAQ11_RS04215	COG0714	Associated with various cellular activities
HAQ11_RS04235	COG0537	adenosine 5'-monophosphoramidase activity
HAQ11_RS04265	COG0314	molybdopterin synthase activity
HAQ11_RS04270	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HAQ11_RS04275	COG0315	cyclic pyranopterin monophosphate synthase activity
HAQ11_RS04285	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HAQ11_RS04290	COG1234	tRNA 3'-trailer cleavage
HAQ11_RS04295	COG3642	lipopolysaccharide core region biosynthetic process
HAQ11_RS04300	COG0859	PFAM glycosyl transferase family 9
HAQ11_RS04310	COG0582	viral genome integration into host DNA
HAQ11_RS04355	COG3501	Rhs element vgr protein
HAQ11_RS04380	COG0631	protein serine/threonine phosphatase activity
HAQ11_RS04390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HAQ11_RS04415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HAQ11_RS04455	COG0544	peptidyl-prolyl cis-trans isomerase activity
HAQ11_RS04505	COG0473	3-isopropylmalate dehydrogenase activity
HAQ11_RS04530	COG0584	glycerophosphoryl diester phosphodiesterase
HAQ11_RS04550	COG3039	Transposase
HAQ11_RS04680	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HAQ11_RS04705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAQ11_RS04715	COG0625	glutathione transferase activity
HAQ11_RS04730	COG3781	membrane
HAQ11_RS04740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HAQ11_RS04770	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HAQ11_RS04790	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HAQ11_RS04815	COG3710	Transcriptional regulator
HAQ11_RS04820	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HAQ11_RS04830	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HAQ11_RS04865	COG0066	3-isopropylmalate dehydratase activity
HAQ11_RS04870	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAQ11_RS04895	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HAQ11_RS04900	COG1538	Outer membrane efflux protein
HAQ11_RS04905	COG1519	Transferase
HAQ11_RS04910	COG1560	Kdo2-lipid A biosynthetic process
HAQ11_RS04955	COG0308	aminopeptidase N
HAQ11_RS04970	COG0330	HflC and HflK could
HAQ11_RS04975	COG0330	HflC and HflK could
HAQ11_RS04995	COG0678	peroxiredoxin activity
HAQ11_RS05005	COG2826	transposase and inactivated derivatives, IS30 family
HAQ11_RS05055	COG3039	Transposase
HAQ11_RS05090	COG3829	transcription factor binding
HAQ11_RS05125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HAQ11_RS05130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HAQ11_RS05140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAQ11_RS05145	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ11_RS05170	COG1399	metal-binding, possibly nucleic acid-binding protein
HAQ11_RS05215	COG1518	maintenance of DNA repeat elements
HAQ11_RS05220	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HAQ11_RS05265	COG2188	Transcriptional regulator
HAQ11_RS05280	COG1450	Type ii and iii secretion system protein
HAQ11_RS05295	COG3166	PFAM Fimbrial assembly family protein
HAQ11_RS05300	COG3156	type II secretion system protein K
HAQ11_RS05305	COG4795	General secretion pathway protein
HAQ11_RS05310	COG2165	general secretion pathway protein
HAQ11_RS05315	COG4970	Tfp pilus assembly protein FimT
HAQ11_RS05320	COG2165	general secretion pathway protein
HAQ11_RS05325	COG1459	type II secretion system
HAQ11_RS05335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HAQ11_RS05340	COG1404	Belongs to the peptidase S8 family
HAQ11_RS05365	COG5295	Hep Hag repeat protein
HAQ11_RS05370	COG0047	phosphoribosylformylglycinamidine synthase activity
HAQ11_RS05370	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAQ11_RS05375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HAQ11_RS05380	COG4974	Belongs to the 'phage' integrase family
HAQ11_RS05390	COG0795	lipopolysaccharide-transporting ATPase activity
HAQ11_RS05400	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HAQ11_RS05415	COG0525	valine-tRNA ligase activity
HAQ11_RS05470	COG3039	Transposase
HAQ11_RS05495	COG1183	phosphatidylcholine synthase activity
HAQ11_RS05505	COG0442	prolyl-tRNA aminoacylation
HAQ11_RS05520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HAQ11_RS05525	COG1127	ABC transporter
HAQ11_RS05530	COG3218	ABC-type transport auxiliary lipoprotein component
HAQ11_RS05530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HAQ11_RS05565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAQ11_RS05570	COG0662	Cupin 2, conserved barrel domain protein
HAQ11_RS05570	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HAQ11_RS05595	COG2086	electron transfer activity
HAQ11_RS05620	COG3328	transposase activity
HAQ11_RS05660	COG0626	cystathionine gamma-synthase activity
HAQ11_RS05705	COG0513	Belongs to the DEAD box helicase family
HAQ11_RS05710	COG0720	synthase
HAQ11_RS05720	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HAQ11_RS05725	COG1956	GAF domain-containing protein
HAQ11_RS05760	COG0339	signal peptide processing
HAQ11_RS05815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HAQ11_RS05820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAQ11_RS05875	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HAQ11_RS05880	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HAQ11_RS05885	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HAQ11_RS05895	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HAQ11_RS05905	COG0356	it plays a direct role in the translocation of protons across the membrane
HAQ11_RS05925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HAQ11_RS05935	COG0508	dehydrogenase complex catalyzes the overall conversion of
HAQ11_RS05965	COG2011	ABC-type metal ion transport system permease component
HAQ11_RS05975	COG0697	spore germination
HAQ11_RS06010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HAQ11_RS06015	COG1187	pseudouridine synthase activity
HAQ11_RS06020	COG2813	Specifically methylates the guanine in position
HAQ11_RS06050	COG2205	protein histidine kinase activity
HAQ11_RS06050	COG2202	Pas domain
HAQ11_RS06075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAQ11_RS06125	COG0745	RESPONSE REGULATOR receiver
HAQ11_RS06140	COG1404	Belongs to the peptidase S8 family
HAQ11_RS06155	COG0842	Transport permease protein
HAQ11_RS06160	COG1131	(ABC) transporter
HAQ11_RS06165	COG0025	NhaP-type Na H and K H
HAQ11_RS06175	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HAQ11_RS06185	COG1573	uracil-dna glycosylase
HAQ11_RS06195	COG3384	dioxygenase
HAQ11_RS06210	COG0667	Aldo Keto reductase
HAQ11_RS06220	COG3590	peptidase
HAQ11_RS06240	COG0531	amino acid
HAQ11_RS06255	COG2972	Histidine kinase
HAQ11_RS06280	COG2204	response regulator
HAQ11_RS06290	COG1271	oxidase subunit
HAQ11_RS06295	COG1294	oxidase, subunit
HAQ11_RS06445	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAQ11_RS06455	COG1560	Kdo2-lipid A biosynthetic process
HAQ11_RS06505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAQ11_RS06505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HAQ11_RS06510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HAQ11_RS06515	COG0242	peptide deformylase activity
HAQ11_RS06520	COG1652	LysM domain
HAQ11_RS06525	COG0758	DNA mediated transformation
HAQ11_RS06530	COG2922	Belongs to the Smg family
HAQ11_RS06545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HAQ11_RS06545	COG1754	DNA topoisomerase type I activity
HAQ11_RS06550	COG0009	L-threonylcarbamoyladenylate synthase
HAQ11_RS06565	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ11_RS06575	COG0616	signal peptide processing
HAQ11_RS06580	COG0534	Mate efflux family protein
HAQ11_RS06600	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HAQ11_RS06635	COG1324	tolerance protein
HAQ11_RS06645	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HAQ11_RS06650	COG0511	ligase activity, forming carbon-carbon bonds
HAQ11_RS06660	COG0439	Biotin carboxylase
HAQ11_RS06705	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HAQ11_RS06725	COG2267	carboxylic ester hydrolase activity
HAQ11_RS06730	COG2267	carboxylic ester hydrolase activity
HAQ11_RS06745	COG0419	ATPase involved in DNA repair
HAQ11_RS06755	COG0151	Belongs to the GarS family
HAQ11_RS06760	COG0577	efflux transmembrane transporter activity
HAQ11_RS06760	COG1136	(ABC) transporter
HAQ11_RS06770	COG1289	transmembrane transporter activity
HAQ11_RS06785	COG2814	Major facilitator Superfamily
HAQ11_RS06800	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HAQ11_RS06835	COG0745	RESPONSE REGULATOR receiver
HAQ11_RS06880	COG0739	heme binding
HAQ11_RS06895	COG2211	Major facilitator Superfamily
HAQ11_RS06900	COG0708	Exodeoxyribonuclease III
HAQ11_RS06915	COG1192	Involved in chromosome partitioning
HAQ11_RS06920	COG1475	DNA binding
HAQ11_RS06935	COG0463	Glycosyl transferase, family 2
HAQ11_RS06960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HAQ11_RS06985	COG4221	oxidoreductase activity
HAQ11_RS07015	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HAQ11_RS07020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAQ11_RS07035	COG3485	protocatechuate 3,4-dioxygenase
HAQ11_RS07040	COG3485	protocatechuate 3,4-dioxygenase
HAQ11_RS07075	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAQ11_RS07080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAQ11_RS07090	COG0045	succinate-CoA ligase (ADP-forming) activity
HAQ11_RS07090	COG1042	CoA-binding domain protein
HAQ11_RS07090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HAQ11_RS07105	COG2239	Acts as a magnesium transporter
HAQ11_RS07120	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HAQ11_RS07130	COG3387	PFAM Glycoside hydrolase 15-related
HAQ11_RS07145	COG3100	YcgL domain-containing protein
HAQ11_RS07150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HAQ11_RS07160	COG0463	Glycosyl transferase, family 2
HAQ11_RS07175	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ11_RS07185	COG0156	8-amino-7-oxononanoate synthase activity
HAQ11_RS07190	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HAQ11_RS07195	COG1040	competence protein
HAQ11_RS07200	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HAQ11_RS07210	COG0628	permease
HAQ11_RS07220	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HAQ11_RS07230	COG1595	DNA-templated transcription, initiation
HAQ11_RS07235	COG0753	catalase activity
HAQ11_RS07280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAQ11_RS07285	COG0180	Tryptophanyl-tRNA synthetase
HAQ11_RS07290	COG3237	CsbD-like
HAQ11_RS07325	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HAQ11_RS07340	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HAQ11_RS07345	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HAQ11_RS07345	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HAQ11_RS07370	COG2205	protein histidine kinase activity
HAQ11_RS07375	COG0745	RESPONSE REGULATOR receiver
HAQ11_RS07385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAQ11_RS07405	COG1566	PFAM secretion protein HlyD family protein
HAQ11_RS07425	COG1199	ATP-dependent helicase activity
HAQ11_RS07465	COG0583	DNA-binding transcription factor activity
HAQ11_RS07510	COG0625	glutathione transferase activity
HAQ11_RS07550	COG4555	ABC transporter
HAQ11_RS07560	COG1476	TRANSCRIPTIONal
HAQ11_RS07585	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HAQ11_RS07590	COG1131	(ABC) transporter
HAQ11_RS07595	COG0842	Transport permease protein
HAQ11_RS07605	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HAQ11_RS07695	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HAQ11_RS07705	COG0564	pseudouridine synthase activity
HAQ11_RS07735	COG0339	signal peptide processing
HAQ11_RS07765	COG3254	rhamnose metabolic process
HAQ11_RS07770	COG0738	Major facilitator superfamily
HAQ11_RS07775	COG1414	Transcriptional regulator
HAQ11_RS07785	COG2205	protein histidine kinase activity
HAQ11_RS07795	COG3459	Glycosyltransferase 36 associated
HAQ11_RS07800	COG2211	Major facilitator Superfamily
HAQ11_RS07805	COG3265	gluconokinase activity
HAQ11_RS07815	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAQ11_RS07890	COG1127	ABC transporter
HAQ11_RS07895	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HAQ11_RS07900	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HAQ11_RS07915	COG2853	Lipoprotein
HAQ11_RS07935	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HAQ11_RS08000	COG0676	glucose-6-phosphate 1-epimerase activity
HAQ11_RS08005	COG3039	Transposase
HAQ11_RS08030	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HAQ11_RS08040	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HAQ11_RS08050	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HAQ11_RS08055	COG1064	alcohol dehydrogenase
HAQ11_RS08100	COG1522	sequence-specific DNA binding
HAQ11_RS08105	COG3186	Phenylalanine-4-hydroxylase
HAQ11_RS08145	COG2937	Belongs to the GPAT DAPAT family
HAQ11_RS08180	COG0284	orotidine-5'-phosphate decarboxylase activity
HAQ11_RS08185	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HAQ11_RS08190	COG3132	Protein of unknown function, DUF480
HAQ11_RS08205	COG0210	DNA helicase
HAQ11_RS08220	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HAQ11_RS08245	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ11_RS08320	COG3501	Rhs element vgr protein
HAQ11_RS08330	COG1166	arginine decarboxylase activity
HAQ11_RS08335	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HAQ11_RS08375	COG0606	chelatase, subunit chli
HAQ11_RS08420	COG0366	Alpha amylase catalytic
HAQ11_RS08425	COG0366	Alpha amylase catalytic
HAQ11_RS08455	COG1609	Transcriptional regulator
HAQ11_RS08505	COG0493	'glutamate synthase
HAQ11_RS08510	COG0067	glutamate synthase
HAQ11_RS08510	COG0070	glutamate synthase
HAQ11_RS08510	COG0069	glutamate synthase activity
HAQ11_RS08570	COG1111	helicase
HAQ11_RS08570	COG1205	dead DEAH box helicase
HAQ11_RS08575	COG1272	protein, Hemolysin III
HAQ11_RS08615	COG1136	(ABC) transporter
HAQ11_RS08680	COG2826	transposase and inactivated derivatives, IS30 family
HAQ11_RS08705	COG3039	Transposase
HAQ11_RS08715	COG1090	epimerase
HAQ11_RS08725	COG0642	Histidine kinase
HAQ11_RS08735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAQ11_RS08775	COG3039	Transposase
HAQ11_RS08785	COG3039	Transposase
HAQ11_RS08860	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HAQ11_RS08935	COG1511	domain protein
HAQ11_RS08935	COG3264	Mechanosensitive ion channel
HAQ11_RS08950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HAQ11_RS08955	COG2354	Protein conserved in bacteria
HAQ11_RS08980	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HAQ11_RS09005	COG0702	epimerase
HAQ11_RS09020	COG1858	cytochrome C peroxidase
HAQ11_RS09105	COG0513	Belongs to the DEAD box helicase family
HAQ11_RS09110	COG3039	Transposase
HAQ11_RS09155	COG1136	(ABC) transporter
HAQ11_RS09165	COG3039	Transposase
HAQ11_RS09175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAQ11_RS09200	COG1755	Isoprenylcysteine carboxyl methyltransferase
HAQ11_RS09205	COG1304	FMN binding
HAQ11_RS09210	COG3039	Transposase
HAQ11_RS09225	COG4772	TonB-dependent receptor
HAQ11_RS09235	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HAQ11_RS09250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAQ11_RS09290	COG0501	Belongs to the peptidase M48B family
HAQ11_RS09300	COG0187	DNA topoisomerase II activity
HAQ11_RS09315	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HAQ11_RS09335	COG0726	polysaccharide deacetylase
HAQ11_RS09345	COG0671	phosphoesterase, PA-phosphatase related
HAQ11_RS09355	COG0584	glycerophosphoryl diester phosphodiesterase
HAQ11_RS09365	COG0861	Integral membrane protein TerC family
HAQ11_RS09370	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HAQ11_RS09385	COG2271	Major facilitator Superfamily
HAQ11_RS09390	COG1929	Belongs to the glycerate kinase type-1 family
HAQ11_RS09480	COG0477	Major facilitator Superfamily
HAQ11_RS09505	COG0302	gtp cyclohydrolase
HAQ11_RS09510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAQ11_RS09555	COG2234	aminopeptidase activity
HAQ11_RS09565	COG4942	peptidase
HAQ11_RS09570	COG0793	Belongs to the peptidase S41A family
HAQ11_RS09620	COG0386	Belongs to the glutathione peroxidase family
HAQ11_RS09630	COG1322	Protein conserved in bacteria
HAQ11_RS09645	COG0531	amino acid
HAQ11_RS09660	COG0210	DNA helicase
HAQ11_RS09675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAQ11_RS09680	COG0583	DNA-binding transcription factor activity
HAQ11_RS09685	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HAQ11_RS09705	COG2159	amidohydrolase
HAQ11_RS09735	COG3540	Alkaline phosphatase
HAQ11_RS09745	COG2091	lysine biosynthetic process via aminoadipic acid
HAQ11_RS09760	COG0708	Exodeoxyribonuclease III
HAQ11_RS09775	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAQ11_RS09780	COG3162	membrane
HAQ11_RS09820	COG3507	Belongs to the glycosyl hydrolase 43 family
HAQ11_RS09840	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ11_RS09845	COG0179	Fumarylacetoacetate (FAA) hydrolase
HAQ11_RS09850	COG4948	Mandelate Racemase Muconate Lactonizing
HAQ11_RS09855	COG4807	Protein conserved in bacteria
HAQ11_RS09860	COG1643	Atp-dependent helicase
HAQ11_RS09870	COG1187	pseudouridine synthase activity
HAQ11_RS09880	COG0667	Aldo Keto reductase
HAQ11_RS09885	COG2130	NADP-dependent
HAQ11_RS09890	COG0656	L-ascorbic acid biosynthetic process
HAQ11_RS09915	COG3039	Transposase
HAQ11_RS09930	COG1752	Esterase of the alpha-beta hydrolase superfamily
HAQ11_RS09940	COG1119	ATPase activity
HAQ11_RS09955	COG1125	glycine betaine transport
HAQ11_RS09955	COG0517	IMP dehydrogenase activity
HAQ11_RS09970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HAQ11_RS09975	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HAQ11_RS09980	COG3550	peptidyl-serine autophosphorylation
HAQ11_RS09985	COG1396	sequence-specific DNA binding
HAQ11_RS10005	COG0489	protein tyrosine kinase activity
HAQ11_RS10010	COG2062	phosphohistidine phosphatase, SixA
HAQ11_RS10020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAQ11_RS10065	COG1968	undecaprenyl-diphosphatase activity
HAQ11_RS10070	COG0174	glutamine synthetase
HAQ11_RS10075	COG0347	Belongs to the P(II) protein family
HAQ11_RS10080	COG0004	ammonium transporteR
HAQ11_RS10085	COG3852	Histidine kinase
HAQ11_RS10090	COG2204	response regulator
HAQ11_RS10095	COG2032	superoxide dismutase activity
HAQ11_RS10100	COG2032	superoxide dismutase activity
HAQ11_RS10145	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HAQ11_RS10150	COG1074	ATP-dependent DNA helicase activity
HAQ11_RS10160	COG3549	Plasmid maintenance system killer
HAQ11_RS10240	COG1764	response to oxidative stress
HAQ11_RS10245	COG1846	Transcriptional regulator
HAQ11_RS10295	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HAQ11_RS10340	COG2211	Major facilitator Superfamily
HAQ11_RS10360	COG3693	PFAM glycoside hydrolase, family 10
HAQ11_RS10385	COG0246	Mannitol dehydrogenase
HAQ11_RS10390	COG1472	Belongs to the glycosyl hydrolase 3 family
HAQ11_RS10400	COG4948	Mandelate Racemase Muconate Lactonizing
HAQ11_RS10410	COG3661	Belongs to the glycosyl hydrolase 67 family
HAQ11_RS10455	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HAQ11_RS10465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HAQ11_RS10475	COG0805	protein transport
HAQ11_RS10485	COG0519	Catalyzes the synthesis of GMP from XMP
HAQ11_RS10485	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HAQ11_RS10500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HAQ11_RS10515	COG0457	Tetratricopeptide repeat
HAQ11_RS10520	COG4771	TonB-dependent receptor
HAQ11_RS10535	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HAQ11_RS10545	COG0697	spore germination
HAQ11_RS10555	COG0523	cobalamin synthesis protein
HAQ11_RS10605	COG1960	acyl-CoA dehydrogenase activity
HAQ11_RS10610	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HAQ11_RS10615	COG4770	biotin carboxylase activity
HAQ11_RS10660	COG2072	flavoprotein involved in K transport
HAQ11_RS10680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HAQ11_RS10730	COG0084	hydrolase, TatD family'
HAQ11_RS10745	COG0583	DNA-binding transcription factor activity
HAQ11_RS10750	COG2814	Major facilitator Superfamily
HAQ11_RS10760	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HAQ11_RS10765	COG1902	pentaerythritol trinitrate reductase activity
HAQ11_RS10795	COG0745	RESPONSE REGULATOR receiver
HAQ11_RS10815	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HAQ11_RS10820	COG0583	DNA-binding transcription factor activity
HAQ11_RS10850	COG0702	epimerase
HAQ11_RS10855	COG1733	regulation of RNA biosynthetic process
HAQ11_RS10905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAQ11_RS10920	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HAQ11_RS10955	COG2911	Protein conserved in bacteria
HAQ11_RS10960	COG0729	surface antigen
HAQ11_RS10975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HAQ11_RS10980	COG3118	belongs to the thioredoxin family
HAQ11_RS10990	COG2884	Cell division ATP-binding protein ftsE
HAQ11_RS10995	COG2177	Part of the ABC transporter FtsEX involved in
HAQ11_RS11000	COG2201	protein-glutamate methylesterase activity
HAQ11_RS11005	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HAQ11_RS11010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAQ11_RS11020	COG1252	NADH dehydrogenase
HAQ11_RS11045	COG0459	protein refolding
HAQ11_RS11055	COG4771	TonB-dependent receptor
HAQ11_RS11070	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HAQ11_RS11110	COG3386	PFAM SMP-30 Gluconolaconase
HAQ11_RS11125	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HAQ11_RS11155	COG2353	YceI-like domain
HAQ11_RS11245	COG0408	coproporphyrinogen oxidase activity
HAQ11_RS11255	COG3039	Transposase
HAQ11_RS11275	COG0129	dihydroxy-acid dehydratase activity
HAQ11_RS11285	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HAQ11_RS11335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HAQ11_RS11340	COG0318	PFAM AMP-dependent synthetase and ligase
HAQ11_RS11345	COG0727	PFAM Uncharacterised protein family (UPF0153)
HAQ11_RS11350	COG0596	Alpha beta hydrolase
HAQ11_RS11365	COG3177	Filamentation induced by cAMP protein fic
HAQ11_RS11370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAQ11_RS11385	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HAQ11_RS11410	COG4191	Histidine kinase
HAQ11_RS11415	COG0028	Belongs to the TPP enzyme family
HAQ11_RS11430	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HAQ11_RS11435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HAQ11_RS11470	COG5383	Protein conserved in bacteria
HAQ11_RS11485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAQ11_RS11490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAQ11_RS11495	COG1473	amidohydrolase
HAQ11_RS11505	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HAQ11_RS11505	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HAQ11_RS11515	COG3328	transposase activity
HAQ11_RS11530	COG3039	Transposase
HAQ11_RS11605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HAQ11_RS11620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HAQ11_RS11625	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HAQ11_RS11635	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
HAQ11_RS11640	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HAQ11_RS11645	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HAQ11_RS11695	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HAQ11_RS11710	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HAQ11_RS11775	COG0358	DNA primase activity
HAQ11_RS11780	COG1295	ribonuclease BN
HAQ11_RS11790	COG1610	YqeY-like protein
HAQ11_RS11800	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HAQ11_RS11805	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HAQ11_RS11840	COG2133	pyrroloquinoline quinone binding
HAQ11_RS11845	COG4682	membrane
HAQ11_RS11880	COG0531	amino acid
HAQ11_RS11915	COG4948	Mandelate Racemase Muconate Lactonizing
HAQ11_RS11925	COG3023	N-Acetylmuramoyl-L-alanine amidase
HAQ11_RS11930	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HAQ11_RS11960	COG3039	Transposase
HAQ11_RS12010	COG0183	Belongs to the thiolase family
HAQ11_RS12045	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HAQ11_RS12055	COG3483	tryptophan 2,3-dioxygenase activity
HAQ11_RS12060	COG3104	oligopeptide transport
HAQ11_RS12080	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HAQ11_RS12090	COG1320	monovalent cation:proton antiporter activity
HAQ11_RS12095	COG2212	antiporter activity
HAQ11_RS12105	COG0651	ATP synthesis coupled electron transport
HAQ11_RS12110	COG1006	Multisubunit Na H antiporter MnhC subunit
HAQ11_RS12115	COG2111	Na H antiporter
HAQ11_RS12115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HAQ11_RS12125	COG3039	Transposase
HAQ11_RS12165	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HAQ11_RS12175	COG0456	acetyltransferase
HAQ11_RS12205	COG4221	oxidoreductase activity
HAQ11_RS12260	COG0697	spore germination
HAQ11_RS12265	COG4305	rare lipoprotein A
HAQ11_RS12270	COG5297	Belongs to the glycosyl hydrolase family 6
HAQ11_RS12280	COG1113	amino acid transport
HAQ11_RS12290	COG0598	Magnesium transport protein CorA
HAQ11_RS12360	COG5297	Belongs to the glycosyl hydrolase family 6
HAQ11_RS12360	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HAQ11_RS12365	COG0659	secondary active sulfate transmembrane transporter activity
HAQ11_RS12400	COG3275	phosphorelay sensor kinase activity
HAQ11_RS12410	COG0181	hydroxymethylbilane synthase activity
HAQ11_RS12435	COG1505	serine-type exopeptidase activity
HAQ11_RS12480	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HAQ11_RS12510	COG0308	aminopeptidase N
HAQ11_RS12515	COG2199	diguanylate cyclase activity
HAQ11_RS12560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAQ11_RS12565	COG1077	Cell shape determining protein MreB Mrl
HAQ11_RS12570	COG1792	Involved in formation and maintenance of cell shape
HAQ11_RS12585	COG0772	Belongs to the SEDS family
HAQ11_RS12610	COG3501	Rhs element vgr protein
HAQ11_RS12620	COG1388	LysM domain
HAQ11_RS12620	COG5632	N-Acetylmuramoyl-L-alanine amidase
HAQ11_RS12620	COG3409	Peptidoglycan-binding domain 1 protein
HAQ11_RS12640	COG2951	lytic endotransglycosylase activity
HAQ11_RS12645	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HAQ11_RS12650	COG1686	Belongs to the peptidase S11 family
HAQ11_RS12665	COG2921	Belongs to the UPF0250 family
HAQ11_RS12700	COG1051	belongs to the nudix hydrolase family
HAQ11_RS12700	COG1056	cytidyltransferase-related domain
HAQ11_RS12735	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HAQ11_RS12740	COG0673	inositol 2-dehydrogenase activity
HAQ11_RS12745	COG2823	Periplasmic or secreted lipoprotein
HAQ11_RS12750	COG4251	negative regulation of phosphorylation
HAQ11_RS12755	COG0784	Response regulator, receiver
HAQ11_RS12760	COG4191	Histidine kinase
HAQ11_RS12765	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HAQ11_RS12815	COG3250	beta-galactosidase activity
HAQ11_RS12830	COG2188	Transcriptional regulator
HAQ11_RS12840	COG1609	Transcriptional regulator
HAQ11_RS12845	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HAQ11_RS12850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HAQ11_RS12860	COG1215	transferase activity, transferring glycosyl groups
HAQ11_RS12865	COG0726	polysaccharide deacetylase
HAQ11_RS12865	COG1649	PFAM Uncharacterised BCR, COG1649
HAQ11_RS12880	COG3039	Transposase
HAQ11_RS12910	COG3039	Transposase
HAQ11_RS12960	COG3039	Transposase
HAQ11_RS12970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HAQ11_RS12975	COG3039	Transposase
HAQ11_RS13010	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HAQ11_RS13030	COG2205	protein histidine kinase activity
HAQ11_RS13065	COG2205	protein histidine kinase activity
HAQ11_RS13070	COG0745	RESPONSE REGULATOR receiver
HAQ11_RS13115	COG0488	(ABC) transporter
HAQ11_RS13135	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HAQ11_RS13155	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HAQ11_RS13155	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HAQ11_RS13175	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HAQ11_RS13180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAQ11_RS13185	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HAQ11_RS13205	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HAQ11_RS13210	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HAQ11_RS13220	COG2205	protein histidine kinase activity
HAQ11_RS13225	COG0745	RESPONSE REGULATOR receiver
HAQ11_RS13230	COG0277	FAD linked oxidase domain protein
HAQ11_RS13235	COG1988	membrane-bound metal-dependent
HAQ11_RS13240	COG0792	nuclease activity
HAQ11_RS13275	COG0275	rRNA processing
HAQ11_RS13280	COG3116	cell division
HAQ11_RS13295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HAQ11_RS13300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HAQ11_RS13315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HAQ11_RS13320	COG1181	Belongs to the D-alanine--D-alanine ligase family
HAQ11_RS13325	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HAQ11_RS13340	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HAQ11_RS13350	COG4942	peptidase
HAQ11_RS13350	COG1388	LysM domain
HAQ11_RS13365	COG0494	nUDIX hydrolase
HAQ11_RS13380	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HAQ11_RS13390	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ11_RS13390	COG3321	synthase
HAQ11_RS13390	COG0604	alcohol dehydrogenase
HAQ11_RS13435	COG2226	methyltransferase
HAQ11_RS13440	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HAQ11_RS13495	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HAQ11_RS13510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAQ11_RS13520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAQ11_RS13525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HAQ11_RS13535	COG0667	Aldo Keto reductase
HAQ11_RS13575	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HAQ11_RS13585	COG2175	clavaminate synthase activity
HAQ11_RS13595	COG4181	ATPase activity
HAQ11_RS13610	COG0642	Histidine kinase
HAQ11_RS13635	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HAQ11_RS13655	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HAQ11_RS13680	COG2967	ApaG domain
HAQ11_RS13685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HAQ11_RS13695	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HAQ11_RS13710	COG0123	including yeast histone deacetylase and acetoin utilization protein
HAQ11_RS13715	COG2096	Adenosyltransferase
HAQ11_RS13725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HAQ11_RS13730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HAQ11_RS13770	COG0583	DNA-binding transcription factor activity
HAQ11_RS13775	COG0318	PFAM AMP-dependent synthetase and ligase
HAQ11_RS13785	COG1024	Enoyl-CoA hydratase
HAQ11_RS13805	COG3386	PFAM SMP-30 Gluconolaconase
HAQ11_RS13930	COG1902	pentaerythritol trinitrate reductase activity
HAQ11_RS13930	COG0446	pyridine nucleotide-disulphide oxidoreductase
HAQ11_RS13935	COG0604	alcohol dehydrogenase
HAQ11_RS13960	COG0156	8-amino-7-oxononanoate synthase activity
HAQ11_RS13965	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HAQ11_RS13970	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HAQ11_RS13975	COG4208	sulfate ABC transporter
HAQ11_RS13980	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HAQ11_RS14010	COG0406	alpha-ribazole phosphatase activity
HAQ11_RS14020	COG0285	dihydrofolate synthase activity
HAQ11_RS14040	COG2833	Protein of unknown function (DUF455)
HAQ11_RS14060	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HAQ11_RS14065	COG0671	phosphoesterase, PA-phosphatase related
HAQ11_RS14070	COG0438	transferase activity, transferring glycosyl groups
HAQ11_RS14080	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HAQ11_RS14095	COG4783	chaperone-mediated protein folding
HAQ11_RS14160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HAQ11_RS14165	COG0583	DNA-binding transcription factor activity
HAQ11_RS14170	COG3634	alkyl hydroperoxide reductase activity
HAQ11_RS14180	COG2890	protein-(glutamine-N5) methyltransferase activity
HAQ11_RS14230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAQ11_RS14230	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAQ11_RS14245	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HAQ11_RS14270	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HAQ11_RS14295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HAQ11_RS14305	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HAQ11_RS14335	COG1295	ribonuclease BN
HAQ11_RS14340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HAQ11_RS14360	COG0521	Mo-molybdopterin cofactor biosynthetic process
HAQ11_RS14370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HAQ11_RS14385	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HAQ11_RS14400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAQ11_RS14410	COG0193	aminoacyl-tRNA hydrolase activity
HAQ11_RS14415	COG0012	GTP binding
HAQ11_RS14445	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HAQ11_RS14450	COG0250	Participates in transcription elongation, termination and antitermination
HAQ11_RS14455	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HAQ11_RS14465	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HAQ11_RS14470	COG0222	ribosome binding
HAQ11_RS14475	COG0085	RNA polymerase activity
HAQ11_RS14480	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAQ11_RS14485	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HAQ11_RS14490	COG0049	tRNA binding
HAQ11_RS14510	COG0051	transcription antitermination factor activity, RNA binding
HAQ11_RS14515	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HAQ11_RS14520	COG0088	Forms part of the polypeptide exit tunnel
HAQ11_RS14525	COG0089	rRNA binding
HAQ11_RS14540	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HAQ11_RS14550	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HAQ11_RS14555	COG0255	Belongs to the universal ribosomal protein uL29 family
HAQ11_RS14560	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HAQ11_RS14565	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HAQ11_RS14575	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HAQ11_RS14605	COG1841	ribosomal large subunit assembly
HAQ11_RS14615	COG0201	protein transport
HAQ11_RS14625	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HAQ11_RS14630	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HAQ11_RS14640	COG0203	ribosomal protein L17
HAQ11_RS14700	COG3551	Protein conserved in bacteria
HAQ11_RS14730	COG2194	sulfuric ester hydrolase activity
HAQ11_RS14740	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HAQ11_RS14745	COG0745	RESPONSE REGULATOR receiver
HAQ11_RS14750	COG0642	Histidine kinase
HAQ11_RS14760	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HAQ11_RS14765	COG2894	cell division
HAQ11_RS14780	COG4585	Histidine kinase
HAQ11_RS14785	COG2197	response regulator
HAQ11_RS14800	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HAQ11_RS14885	COG3501	Rhs element vgr protein
HAQ11_RS14940	COG3039	Transposase
HAQ11_RS14950	COG3501	Rhs element vgr protein
HAQ11_RS14965	COG3501	Rhs element vgr protein
HAQ11_RS15030	COG3501	Rhs element vgr protein
HAQ11_RS15135	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HAQ11_RS15155	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HAQ11_RS15160	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
HAQ11_RS15175	COG3039	Transposase
HAQ11_RS15180	COG0732	type I restriction modification DNA specificity domain
HAQ11_RS15195	COG3039	Transposase
HAQ11_RS15200	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HAQ11_RS15235	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HAQ11_RS15300	COG1297	OPT oligopeptide transporter protein
HAQ11_RS15305	COG3039	Transposase
HAQ11_RS15325	COG0823	Involved in the tonB-independent uptake of proteins
HAQ11_RS15325	COG1506	peptidase
HAQ11_RS15355	COG1917	Cupin 2, conserved barrel domain protein
HAQ11_RS15355	COG2207	Transcriptional regulator
HAQ11_RS15375	COG3039	Transposase
HAQ11_RS15395	COG0753	catalase activity
HAQ11_RS15435	COG0469	pyruvate kinase activity
HAQ11_RS15440	COG3588	fructose-bisphosphate aldolase
HAQ11_RS15445	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HAQ11_RS15495	COG0784	Response regulator, receiver
HAQ11_RS15495	COG2205	protein histidine kinase activity
HAQ11_RS15495	COG2198	Histidine kinase
HAQ11_RS15515	COG0175	sulfate reduction
HAQ11_RS15520	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HAQ11_RS15525	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HAQ11_RS15530	COG0175	sulfate reduction
HAQ11_RS15535	COG2895	sulfate adenylyltransferase (ATP) activity
HAQ11_RS15535	COG0529	Catalyzes the synthesis of activated sulfate
HAQ11_RS15545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAQ11_RS15550	COG0308	aminopeptidase N
HAQ11_RS15570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAQ11_RS15600	COG1970	mechanosensitive ion channel activity
HAQ11_RS15630	COG0471	metal ion transport
HAQ11_RS15630	COG3273	potassium ion transport
HAQ11_RS15640	COG2022	thiamine diphosphate biosynthetic process
HAQ11_RS15720	COG3039	Transposase
HAQ11_RS15725	COG3039	Transposase
HAQ11_RS15805	COG3118	belongs to the thioredoxin family
HAQ11_RS15830	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HAQ11_RS15855	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HAQ11_RS15880	COG2968	Membrane
HAQ11_RS15890	COG1530	ribonuclease E activity
HAQ11_RS15895	COG3164	Protein of unknown function
HAQ11_RS15905	COG0312	modulator of DNA gyrase
HAQ11_RS15910	COG3028	Belongs to the UPF0307 family
HAQ11_RS15915	COG0312	modulator of DNA gyrase
HAQ11_RS15940	COG0142	geranyltranstransferase activity
HAQ11_RS15945	COG1722	exodeoxyribonuclease VII activity
HAQ11_RS15950	COG0037	tRNA processing
HAQ11_RS15955	COG1785	Belongs to the alkaline phosphatase family
HAQ11_RS15960	COG1301	dicarboxylic acid transport
HAQ11_RS15975	COG0791	NLP P60 protein
HAQ11_RS15980	COG0791	NLP P60 protein
HAQ11_RS15985	COG1047	Peptidyl-prolyl cis-trans
HAQ11_RS15990	COG2311	Membrane
HAQ11_RS15995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAQ11_RS16035	COG0489	protein tyrosine kinase activity
HAQ11_RS16040	COG0717	Belongs to the dCTP deaminase family
HAQ11_RS16060	COG0412	Dienelactone hydrolase
HAQ11_RS16070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HAQ11_RS16115	COG2890	protein-(glutamine-N5) methyltransferase activity
HAQ11_RS16120	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HAQ11_RS16125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAQ11_RS16130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HAQ11_RS16150	COG0101	tRNA pseudouridine synthase activity
HAQ11_RS16155	COG0135	phosphoribosylanthranilate isomerase activity
HAQ11_RS16180	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HAQ11_RS16185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAQ11_RS16235	COG0149	triose-phosphate isomerase activity
HAQ11_RS16250	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HAQ11_RS16260	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HAQ11_RS16265	COG0649	NAD binding
HAQ11_RS16270	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HAQ11_RS16275	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HAQ11_RS16280	COG1034	ATP synthesis coupled electron transport
HAQ11_RS16315	COG1007	ATP synthesis coupled electron transport
HAQ11_RS16325	COG0779	Required for maturation of 30S ribosomal subunits
HAQ11_RS16330	COG0195	Participates in both transcription termination and antitermination
HAQ11_RS16350	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HAQ11_RS16355	COG1185	polyribonucleotide nucleotidyltransferase activity
HAQ11_RS16390	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HAQ11_RS16400	COG2095	MarC family integral membrane protein
HAQ11_RS16415	COG1611	Belongs to the LOG family
HAQ11_RS16455	COG4969	Belongs to the N-Me-Phe pilin family
HAQ11_RS16495	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HAQ11_RS16565	COG0438	transferase activity, transferring glycosyl groups
HAQ11_RS16570	COG0438	transferase activity, transferring glycosyl groups
HAQ11_RS16580	COG0438	transferase activity, transferring glycosyl groups
HAQ11_RS16620	COG3040	lipid binding
HAQ11_RS16710	COG0784	Response regulator, receiver
HAQ11_RS16710	COG4191	Histidine kinase
HAQ11_RS16730	COG0552	protein localization to endoplasmic reticulum
HAQ11_RS16740	COG3938	Belongs to the proline racemase family
HAQ11_RS16745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAQ11_RS16760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAQ11_RS16770	COG0006	proline dipeptidase activity
HAQ11_RS16785	COG0531	amino acid
HAQ11_RS16835	COG4206	TonB-dependent receptor
HAQ11_RS16860	COG4206	TonB-dependent receptor
HAQ11_RS16865	COG3328	transposase activity
HAQ11_RS16930	COG0746	molybdenum cofactor guanylyltransferase activity
HAQ11_RS16955	COG1648	precorrin-2 dehydrogenase activity
HAQ11_RS16955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HAQ11_RS16995	COG3039	Transposase
HAQ11_RS17000	COG3039	Transposase
HAQ11_RS17035	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HAQ11_RS17055	COG3039	Transposase
HAQ11_RS17080	COG1530	ribonuclease E activity
HAQ11_RS17090	COG3064	Membrane
HAQ11_RS17095	COG0428	transporter
HAQ11_RS17100	COG0428	transporter
HAQ11_RS17110	COG2154	pterin-4-alpha-carbinolamine dehydratase
HAQ11_RS17115	COG0316	Belongs to the HesB IscA family
HAQ11_RS17115	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HAQ11_RS17160	COG3039	Transposase
HAQ11_RS17175	COG3039	Transposase
HAQ11_RS17250	COG3501	Rhs element vgr protein
HAQ11_RS17285	COG0631	protein serine/threonine phosphatase activity
HAQ11_RS17290	COG0515	serine threonine protein kinase
HAQ11_RS17325	COG1858	cytochrome C peroxidase
HAQ11_RS17375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAQ11_RS17380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAQ11_RS17400	COG2201	protein-glutamate methylesterase activity
HAQ11_RS17445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HAQ11_RS17465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HAQ11_RS17480	COG1595	DNA-templated transcription, initiation
HAQ11_RS17530	COG2244	polysaccharide biosynthetic process
HAQ11_RS17560	COG2264	protein methyltransferase activity
HAQ11_RS17570	COG0438	transferase activity, transferring glycosyl groups
HAQ11_RS17590	COG1136	(ABC) transporter
HAQ11_RS17595	COG1132	(ABC) transporter
HAQ11_RS17605	COG0477	Major facilitator Superfamily
HAQ11_RS17615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAQ11_RS17630	COG1253	flavin adenine dinucleotide binding
HAQ11_RS17640	COG0306	phosphate transporter
HAQ11_RS17645	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HAQ11_RS17670	COG0504	CTP synthase activity
HAQ11_RS17675	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HAQ11_RS17685	COG0148	phosphopyruvate hydratase activity
HAQ11_RS17690	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HAQ11_RS17705	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HAQ11_RS17715	COG2840	Smr protein MutS2
HAQ11_RS17720	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HAQ11_RS17725	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HAQ11_RS17730	COG1238	metal cluster binding
HAQ11_RS17745	COG1534	Rna-binding protein
HAQ11_RS17750	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HAQ11_RS17760	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HAQ11_RS17775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HAQ11_RS17780	COG1546	Belongs to the CinA family
HAQ11_RS17795	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HAQ11_RS17800	COG2137	regulation of response to DNA damage stimulus
HAQ11_RS17805	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HAQ11_RS17810	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HAQ11_RS17830	COG0305	Participates in initiation and elongation during chromosome replication
HAQ11_RS17835	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HAQ11_RS17855	COG1741	Belongs to the pirin family
HAQ11_RS17860	COG0583	DNA-binding transcription factor activity
HAQ11_RS17890	COG0351	phosphomethylpyrimidine kinase
HAQ11_RS17900	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HAQ11_RS17905	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HAQ11_RS17920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAQ11_RS17930	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HAQ11_RS17935	COG3734	2-keto-3-deoxy-galactonokinase
HAQ11_RS17945	COG4948	Mandelate Racemase Muconate Lactonizing
HAQ11_RS17950	COG0800	Aldolase
HAQ11_RS17965	COG1501	Belongs to the glycosyl hydrolase 31 family
HAQ11_RS17975	COG1070	Carbohydrate kinase
HAQ11_RS17985	COG0477	Major facilitator Superfamily
HAQ11_RS18005	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HAQ11_RS18055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HAQ11_RS18060	COG2258	MOSC domain
HAQ11_RS18070	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HAQ11_RS18075	COG0505	Belongs to the CarA family
HAQ11_RS18085	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HAQ11_RS18090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HAQ11_RS18100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HAQ11_RS18160	COG0784	Response regulator, receiver
HAQ11_RS18160	COG2198	Histidine kinase
HAQ11_RS18160	COG2205	protein histidine kinase activity
HAQ11_RS18165	COG1024	Enoyl-CoA hydratase
HAQ11_RS18170	COG0318	PFAM AMP-dependent synthetase and ligase
HAQ11_RS18200	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAQ11_RS18235	COG0840	transmembrane signaling receptor activity
HAQ11_RS18255	COG0835	chemotaxis
HAQ11_RS18270	COG0840	transmembrane signaling receptor activity
HAQ11_RS18275	COG0840	transmembrane signaling receptor activity
HAQ11_RS18280	COG0840	transmembrane signaling receptor activity
HAQ11_RS18285	COG0840	transmembrane signaling receptor activity
HAQ11_RS18295	COG0840	transmembrane signaling receptor activity
HAQ11_RS18305	COG0840	transmembrane signaling receptor activity
HAQ11_RS18315	COG0840	transmembrane signaling receptor activity
HAQ11_RS18335	COG0745	RESPONSE REGULATOR receiver
HAQ11_RS18345	COG0835	chemotaxis
HAQ11_RS18355	COG1360	Flagellar Motor Protein
HAQ11_RS18360	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HAQ11_RS18380	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HAQ11_RS18390	COG4771	TonB-dependent receptor
HAQ11_RS18420	COG3039	Transposase
HAQ11_RS18465	COG3501	Rhs element vgr protein
HAQ11_RS18485	COG3501	Rhs element vgr protein
HAQ11_RS18505	COG3501	Rhs element vgr protein
HAQ11_RS18555	COG3039	Transposase
HAQ11_RS18570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HAQ11_RS18570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HAQ11_RS18575	COG1105	Belongs to the carbohydrate kinase PfkB family
HAQ11_RS18580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAQ11_RS18580	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HAQ11_RS18585	COG1609	Transcriptional regulator
HAQ11_RS18605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAQ11_RS18610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAQ11_RS18620	COG2902	Dehydrogenase
HAQ11_RS18625	COG3039	Transposase
HAQ11_RS18635	COG0784	Response regulator, receiver
HAQ11_RS18635	COG2205	protein histidine kinase activity
HAQ11_RS18635	COG5002	protein histidine kinase activity
HAQ11_RS18640	COG2733	membrane
HAQ11_RS18650	COG1121	(ABC) transporter
HAQ11_RS18670	COG2223	nitrite transmembrane transporter activity
HAQ11_RS18680	COG0243	molybdopterin cofactor binding
HAQ11_RS18690	COG0477	Major facilitator Superfamily
HAQ11_RS18700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAQ11_RS18705	COG0174	glutamine synthetase
HAQ11_RS18740	COG3842	ATPase activity
HAQ11_RS18750	COG1177	transmembrane transport
HAQ11_RS18760	COG1012	belongs to the aldehyde dehydrogenase family
HAQ11_RS18775	COG4535	Mg2 and Co2 transporter CorC
HAQ11_RS18795	COG1702	phosphate starvation-inducible protein PhoH
HAQ11_RS18820	COG0741	lytic transglycosylase activity
HAQ11_RS18825	COG0723	plastoquinol--plastocyanin reductase activity
HAQ11_RS18830	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HAQ11_RS18835	COG2857	Cytochrome c1
HAQ11_RS18840	COG0625	glutathione transferase activity
HAQ11_RS18845	COG2969	positive regulation of protein catabolic process
HAQ11_RS18880	COG3328	transposase activity
HAQ11_RS18955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HAQ11_RS18980	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HAQ11_RS18985	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HAQ11_RS18985	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HAQ11_RS18990	COG0802	atpase or kinase
HAQ11_RS18995	COG0860	N-Acetylmuramoyl-L-alanine amidase
HAQ11_RS19000	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HAQ11_RS19020	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ11_RS19040	COG2081	HI0933 family
HAQ11_RS19045	COG4681	YaeQ
HAQ11_RS19050	COG1671	Belongs to the UPF0178 family
HAQ11_RS19060	COG0625	glutathione transferase activity
HAQ11_RS19080	COG0513	Belongs to the DEAD box helicase family
HAQ11_RS19105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HAQ11_RS19110	COG0483	inositol monophosphate 1-phosphatase activity
HAQ11_RS19125	COG5001	Diguanylate cyclase
HAQ11_RS19125	COG3300	MHYT domain
HAQ11_RS19130	COG1509	lysine 2,3-aminomutase activity
HAQ11_RS19145	COG0402	S-adenosylhomocysteine deaminase activity
HAQ11_RS19150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HAQ11_RS19175	COG4677	pectinesterase activity
HAQ11_RS19185	COG3039	Transposase
HAQ11_RS19220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HAQ11_RS19245	COG2166	iron-sulfur cluster assembly
HAQ11_RS19260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HAQ11_RS19265	COG0137	argininosuccinate synthase activity
HAQ11_RS19275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HAQ11_RS19280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HAQ11_RS19295	COG0165	Argininosuccinate lyase
HAQ11_RS19315	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HAQ11_RS19350	COG1271	oxidase subunit
HAQ11_RS19370	COG4988	ABC transporter
HAQ11_RS19375	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HAQ11_RS19460	COG3039	Transposase
HAQ11_RS19490	COG0784	Response regulator, receiver
HAQ11_RS19490	COG0643	Histidine kinase
HAQ11_RS19490	COG2198	Histidine kinase
HAQ11_RS19535	COG5001	Diguanylate cyclase
HAQ11_RS19535	COG3300	MHYT domain
HAQ11_RS19540	COG5001	Diguanylate cyclase
HAQ11_RS19540	COG3300	MHYT domain
HAQ11_RS19545	COG1684	flagellar biosynthetic protein fliR
HAQ11_RS19560	COG3190	flagellar
HAQ11_RS19610	COG1677	Flagellar hook-basal body complex protein FliE
HAQ11_RS19640	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ11_RS19650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAQ11_RS19670	COG2201	protein-glutamate methylesterase activity
HAQ11_RS19700	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HAQ11_RS19705	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HAQ11_RS19745	COG4787	bacterial-type flagellum-dependent cell motility
HAQ11_RS19755	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HAQ11_RS19760	COG1558	bacterial-type flagellum-dependent cell motility
HAQ11_RS19770	COG0784	Response regulator, receiver
HAQ11_RS19770	COG0835	chemotaxis
HAQ11_RS19790	COG5002	protein histidine kinase activity
HAQ11_RS19800	COG4585	Histidine kinase
HAQ11_RS19805	COG5001	Diguanylate cyclase
HAQ11_RS19830	COG0482	sulfurtransferase activity
HAQ11_RS19845	COG0542	response to heat
HAQ11_RS19870	COG0492	ferredoxin-NADP+ reductase activity
HAQ11_RS19875	COG1674	ftsk spoiiie
HAQ11_RS19895	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HAQ11_RS19915	COG0038	chloride channel
HAQ11_RS19920	COG0183	Belongs to the thiolase family
HAQ11_RS19925	COG1250	3-hydroxyacyl-CoA dehydrogenase
HAQ11_RS19925	COG1024	Enoyl-CoA hydratase
HAQ11_RS19940	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HAQ11_RS19950	COG1426	Protein conserved in bacteria
HAQ11_RS19960	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAQ11_RS19970	COG0303	'Molybdopterin
HAQ11_RS20000	COG3039	Transposase
HAQ11_RS20010	COG3039	Transposase
HAQ11_RS20045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HAQ11_RS20065	COG0742	ribosomal rna small subunit methyltransferase
HAQ11_RS20070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HAQ11_RS20080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HAQ11_RS20085	COG0405	Gamma-glutamyltransferase
HAQ11_RS20165	COG0343	queuine tRNA-ribosyltransferase activity
HAQ11_RS20170	COG1862	Preprotein translocase
HAQ11_RS20175	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HAQ11_RS20180	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HAQ11_RS20210	COG3328	transposase activity
HAQ11_RS20225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HAQ11_RS20235	COG0704	Plays a role in the regulation of phosphate uptake
HAQ11_RS20250	COG0573	inorganic phosphate transmembrane transporter activity
HAQ11_RS20255	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HAQ11_RS20295	COG3039	Transposase
HAQ11_RS20310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HAQ11_RS20320	COG1024	Enoyl-CoA hydratase
HAQ11_RS20330	COG0494	nUDIX hydrolase
HAQ11_RS20375	COG0116	Belongs to the methyltransferase superfamily
HAQ11_RS20375	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HAQ11_RS20400	COG0667	Aldo Keto reductase
HAQ11_RS20410	COG2925	Exonuclease
HAQ11_RS20435	COG0288	reversible hydration of carbon dioxide
HAQ11_RS20465	COG0316	Belongs to the HesB IscA family
HAQ11_RS20470	COG0360	Binds together with S18 to 16S ribosomal RNA
HAQ11_RS20480	COG0359	binds to the 23S rRNA
HAQ11_RS20490	COG3115	cell septum assembly
HAQ11_RS20505	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HAQ11_RS20520	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HAQ11_RS20545	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HAQ11_RS20555	COG2986	histidine ammonia-lyase
HAQ11_RS20560	COG1228	amidohydrolase
HAQ11_RS20600	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HAQ11_RS20610	COG1605	Chorismate mutase
HAQ11_RS20610	COG0077	Prephenate dehydratase
HAQ11_RS20615	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HAQ11_RS20655	COG4566	intracellular signal transduction
HAQ11_RS20700	COG0860	N-Acetylmuramoyl-L-alanine amidase
HAQ11_RS20705	COG1469	GTP cyclohydrolase I activity
HAQ11_RS20715	COG0617	tRNA 3'-terminal CCA addition
HAQ11_RS20760	COG1472	Belongs to the glycosyl hydrolase 3 family
HAQ11_RS20780	COG5001	Diguanylate cyclase
HAQ11_RS20780	COG2203	Gaf domain
HAQ11_RS20780	COG3706	GGDEF domain
HAQ11_RS20780	COG4251	negative regulation of phosphorylation
HAQ11_RS20865	COG0386	Belongs to the glutathione peroxidase family
HAQ11_RS20920	COG3706	GGDEF domain
HAQ11_RS20945	COG0784	Response regulator, receiver
HAQ11_RS20945	COG2205	protein histidine kinase activity
HAQ11_RS20945	COG5002	protein histidine kinase activity
HAQ11_RS20975	COG0800	Aldolase
HAQ11_RS20980	COG0129	dihydroxy-acid dehydratase activity
HAQ11_RS20985	COG0363	glucosamine-6-phosphate deaminase activity
HAQ11_RS20995	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HAQ11_RS21010	COG0354	folic acid binding
HAQ11_RS21025	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HAQ11_RS21040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HAQ11_RS21055	COG4591	ABC-type transport system involved in lipoprotein release permease component
HAQ11_RS21080	COG0811	peptide transport
HAQ11_RS21095	COG1663	tetraacyldisaccharide 4'-kinase activity
HAQ11_RS21105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HAQ11_RS21115	COG0322	excinuclease ABC activity
HAQ11_RS21150	COG3328	transposase activity
HAQ11_RS21170	COG3039	Transposase
HAQ11_RS21190	COG2801	Transposase and inactivated derivatives
HAQ11_RS21200	COG2201	protein-glutamate methylesterase activity
HAQ11_RS21330	COG0653	protein targeting
HAQ11_RS21365	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HAQ11_RS21365	COG0140	phosphoribosyl-ATP diphosphatase activity
HAQ11_RS21375	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HAQ11_RS21385	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HAQ11_RS21385	COG0131	Imidazoleglycerol-phosphate dehydratase
HAQ11_RS21400	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HAQ11_RS21420	COG0124	histidyl-tRNA synthetase
HAQ11_RS21435	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HAQ11_RS21470	COG1012	belongs to the aldehyde dehydrogenase family
HAQ11_RS21500	COG0697	spore germination
HAQ11_RS21505	COG1794	racemase activity, acting on amino acids and derivatives
HAQ11_RS21530	COG0671	phosphoesterase, PA-phosphatase related
HAQ11_RS21545	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HAQ11_RS21560	COG2183	response to ionizing radiation
HAQ11_RS21570	COG0723	plastoquinol--plastocyanin reductase activity
HAQ11_RS21570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAQ11_RS21585	COG3243	poly(R)-hydroxyalkanoic acid synthase
HAQ11_RS21595	COG1183	phosphatidylcholine synthase activity
HAQ11_RS21600	COG1028	Short-chain dehydrogenase reductase Sdr
HAQ11_RS21615	COG3039	Transposase
HAQ11_RS21655	COG0668	transmembrane transport
HAQ11_RS21675	COG1914	H( )-stimulated, divalent metal cation uptake system
HAQ11_RS21695	COG0583	DNA-binding transcription factor activity
HAQ11_RS21725	COG0583	DNA-binding transcription factor activity
HAQ11_RS21730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HAQ11_RS21735	COG3002	Belongs to the UPF0753 family
HAQ11_RS21750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HAQ11_RS21770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HAQ11_RS21780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HAQ11_RS21785	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HAQ11_RS21795	COG0776	regulation of translation
HAQ11_RS21800	COG0539	negative regulation of cytoplasmic translation
HAQ11_RS21805	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HAQ11_RS21820	COG2957	Belongs to the agmatine deiminase family
HAQ11_RS21830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HAQ11_RS21855	COG0395	ABC-type sugar transport system, permease component
HAQ11_RS21860	COG1175	transmembrane transport
HAQ11_RS21890	COG2350	Protein conserved in bacteria
HAQ11_RS21895	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HAQ11_RS21900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HAQ11_RS21905	COG1187	pseudouridine synthase activity
HAQ11_RS21930	COG0436	Aminotransferase
HAQ11_RS21995	COG0277	FAD linked oxidase domain protein
HAQ11_RS22000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HAQ11_RS22010	COG0531	amino acid
HAQ11_RS22015	COG0531	amino acid
HAQ11_RS22025	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HAQ11_RS22055	COG2201	protein-glutamate methylesterase activity
HAQ11_RS22100	COG0583	DNA-binding transcription factor activity
HAQ11_RS22110	COG3039	Transposase
HAQ11_RS22160	COG3039	Transposase
HAQ11_RS22165	COG3039	Transposase
HAQ11_RS22180	COG1278	Cold shock
HAQ11_RS22190	COG3328	transposase activity
HAQ11_RS22210	COG3039	Transposase
HAQ11_RS22220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAQ11_RS22240	COG0557	exoribonuclease II activity
HAQ11_RS22265	COG1960	acyl-CoA dehydrogenase activity
HAQ11_RS22270	COG2226	methyltransferase
HAQ11_RS22275	COG0646	methionine synthase
HAQ11_RS22275	COG1410	methionine synthase
HAQ11_RS22280	COG0646	methionine synthase
HAQ11_RS22280	COG1410	methionine synthase
HAQ11_RS22290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAQ11_RS22315	COG2900	Belongs to the SlyX family
HAQ11_RS22330	COG0386	Belongs to the glutathione peroxidase family
HAQ11_RS22340	COG1725	Transcriptional regulator
HAQ11_RS22345	COG1131	(ABC) transporter
HAQ11_RS22425	COG2850	peptidyl-arginine hydroxylation
HAQ11_RS22460	COG1132	(ABC) transporter
HAQ11_RS22475	COG0583	DNA-binding transcription factor activity
HAQ11_RS22490	COG0287	Prephenate dehydrogenase
HAQ11_RS22490	COG1605	Chorismate mutase
HAQ11_RS22495	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HAQ11_RS22500	COG0484	heat shock protein binding
HAQ11_RS22505	COG0443	Heat shock 70 kDa protein
HAQ11_RS22510	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HAQ11_RS22520	COG0497	DNA recombination
HAQ11_RS22530	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAQ11_RS22535	COG2914	Belongs to the UPF0125 (RnfH) family
HAQ11_RS22560	COG1960	acyl-CoA dehydrogenase activity
HAQ11_RS22570	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HAQ11_RS22615	COG2814	Major facilitator Superfamily
HAQ11_RS22620	COG1566	PFAM secretion protein HlyD family protein
HAQ11_RS22655	COG4774	siderophore transport
HAQ11_RS22665	COG0367	asparagine synthase
HAQ11_RS22680	COG1393	Belongs to the ArsC family
HAQ11_RS22740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HAQ11_RS22755	COG0233	cytoplasmic translational termination
HAQ11_RS22765	COG0575	Belongs to the CDS family
HAQ11_RS22775	COG0750	zinc metalloprotease
HAQ11_RS22790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HAQ11_RS22795	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HAQ11_RS22815	COG0825	malonyl-CoA metabolic process
HAQ11_RS22825	COG4771	TonB-dependent receptor
HAQ11_RS22830	COG1131	(ABC) transporter
HAQ11_RS22900	COG0529	Catalyzes the synthesis of activated sulfate
HAQ11_RS22900	COG2895	sulfate adenylyltransferase (ATP) activity
HAQ11_RS22935	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage