locus-tag	class	description
XOO_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XOO_RS00020	COG0187	DNA topoisomerase II activity
XOO_RS00030	COG0501	Belongs to the peptidase M48B family
XOO_RS00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XOO_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XOO_RS00080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XOO_RS00090	COG4772	TonB-dependent receptor
XOO_RS00105	COG3039	Transposase
XOO_RS00110	COG1304	FMN binding
XOO_RS00115	COG1755	Isoprenylcysteine carboxyl methyltransferase
XOO_RS00130	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XOO_RS00135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XOO_RS00150	COG3039	Transposase
XOO_RS00170	COG3039	Transposase
XOO_RS00230	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS00255	COG3039	Transposase
XOO_RS00265	COG1090	epimerase
XOO_RS00270	COG0642	Histidine kinase
XOO_RS00280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XOO_RS00320	COG3039	Transposase
XOO_RS00330	COG3039	Transposase
XOO_RS00405	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XOO_RS00490	COG1511	domain protein
XOO_RS00490	COG3264	Mechanosensitive ion channel
XOO_RS00500	COG3293	Transposase
XOO_RS00510	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XOO_RS00515	COG2354	Protein conserved in bacteria
XOO_RS00520	COG1649	PFAM Uncharacterised BCR, COG1649
XOO_RS00540	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XOO_RS00565	COG0702	epimerase
XOO_RS00570	COG1858	cytochrome C peroxidase
XOO_RS00655	COG0513	Belongs to the DEAD box helicase family
XOO_RS00665	COG3039	Transposase
XOO_RS00685	COG0508	dehydrogenase complex catalyzes the overall conversion of
XOO_RS00720	COG3039	Transposase
XOO_RS00760	COG1136	(ABC) transporter
XOO_RS00775	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS00805	COG1272	protein, Hemolysin III
XOO_RS00810	COG1111	helicase
XOO_RS00810	COG1205	dead DEAH box helicase
XOO_RS00865	COG0070	glutamate synthase
XOO_RS00865	COG0067	glutamate synthase
XOO_RS00865	COG0069	glutamate synthase activity
XOO_RS00870	COG0493	'glutamate synthase
XOO_RS00890	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS00920	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XOO_RS00925	COG1609	Transcriptional regulator
XOO_RS00955	COG0366	Alpha amylase catalytic
XOO_RS00960	COG2801	Transposase and inactivated derivatives
XOO_RS00975	COG3328	transposase activity
XOO_RS01005	COG0606	chelatase, subunit chli
XOO_RS01035	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XOO_RS01040	COG1166	arginine decarboxylase activity
XOO_RS01095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XOO_RS01120	COG1028	Short-chain dehydrogenase reductase Sdr
XOO_RS01135	COG2801	Transposase and inactivated derivatives
XOO_RS01160	COG0210	DNA helicase
XOO_RS01170	COG3132	Protein of unknown function, DUF480
XOO_RS01175	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XOO_RS01180	COG0284	orotidine-5'-phosphate decarboxylase activity
XOO_RS01210	COG2937	Belongs to the GPAT DAPAT family
XOO_RS01230	COG2963	transposase activity
XOO_RS01245	COG2755	lipolytic protein G-D-S-L family
XOO_RS01255	COG3186	Phenylalanine-4-hydroxylase
XOO_RS01260	COG1522	sequence-specific DNA binding
XOO_RS01275	COG4773	Receptor
XOO_RS01280	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS01320	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XOO_RS01325	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XOO_RS01330	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XOO_RS01335	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS01355	COG0676	glucose-6-phosphate 1-epimerase activity
XOO_RS01375	COG3135	benzoate transporter
XOO_RS01380	COG3135	benzoate transporter
XOO_RS01415	COG2963	transposase activity
XOO_RS01425	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XOO_RS01435	COG3293	Transposase
XOO_RS01450	COG2853	Lipoprotein
XOO_RS01465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XOO_RS01470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XOO_RS01475	COG1127	ABC transporter
XOO_RS01505	COG3293	Transposase
XOO_RS01535	COG2801	Transposase and inactivated derivatives
XOO_RS01540	COG2963	transposase activity
XOO_RS01560	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XOO_RS01565	COG3293	Transposase
XOO_RS01575	COG3265	gluconokinase activity
XOO_RS01580	COG2211	Major facilitator Superfamily
XOO_RS01585	COG3459	Glycosyltransferase 36 associated
XOO_RS01600	COG2205	protein histidine kinase activity
XOO_RS01610	COG1414	Transcriptional regulator
XOO_RS01615	COG0738	Major facilitator superfamily
XOO_RS01620	COG3254	rhamnose metabolic process
XOO_RS01640	COG0339	signal peptide processing
XOO_RS01665	COG0564	pseudouridine synthase activity
XOO_RS01675	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XOO_RS01690	COG1181	Belongs to the D-alanine--D-alanine ligase family
XOO_RS01725	COG2963	transposase activity
XOO_RS01770	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XOO_RS01780	COG0842	Transport permease protein
XOO_RS01785	COG1131	(ABC) transporter
XOO_RS01790	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XOO_RS01810	COG1476	TRANSCRIPTIONal
XOO_RS01820	COG4555	ABC transporter
XOO_RS01855	COG3293	Transposase
XOO_RS01865	COG0625	glutathione transferase activity
XOO_RS01900	COG0583	DNA-binding transcription factor activity
XOO_RS01930	COG1199	ATP-dependent helicase activity
XOO_RS01950	COG1566	PFAM secretion protein HlyD family protein
XOO_RS01975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XOO_RS02015	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XOO_RS02015	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XOO_RS02020	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XOO_RS02035	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XOO_RS02070	COG3237	CsbD-like
XOO_RS02075	COG0180	Tryptophanyl-tRNA synthetase
XOO_RS02080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XOO_RS02125	COG0753	catalase activity
XOO_RS02130	COG1595	DNA-templated transcription, initiation
XOO_RS02140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XOO_RS02150	COG0628	permease
XOO_RS02160	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XOO_RS02165	COG1040	competence protein
XOO_RS02170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XOO_RS02175	COG0156	8-amino-7-oxononanoate synthase activity
XOO_RS02185	COG1028	Short-chain dehydrogenase reductase Sdr
XOO_RS02200	COG0463	Glycosyl transferase, family 2
XOO_RS02210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XOO_RS02215	COG3100	YcgL domain-containing protein
XOO_RS02230	COG3387	PFAM Glycoside hydrolase 15-related
XOO_RS02235	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XOO_RS02250	COG2239	Acts as a magnesium transporter
XOO_RS02260	COG1042	CoA-binding domain protein
XOO_RS02260	COG0045	succinate-CoA ligase (ADP-forming) activity
XOO_RS02260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XOO_RS02270	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XOO_RS02275	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XOO_RS02295	COG2963	transposase activity
XOO_RS02300	COG2801	Transposase and inactivated derivatives
XOO_RS02315	COG3485	protocatechuate 3,4-dioxygenase
XOO_RS02320	COG3485	protocatechuate 3,4-dioxygenase
XOO_RS02330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XOO_RS02335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XOO_RS02345	COG1414	Transcriptional regulator
XOO_RS02355	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS02360	COG4221	oxidoreductase activity
XOO_RS02375	COG0018	arginyl-trna synthetase
XOO_RS02380	COG2003	Belongs to the UPF0758 family
XOO_RS02385	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XOO_RS02390	COG0756	dUTP diphosphatase activity
XOO_RS02410	COG0463	Glycosyl transferase, family 2
XOO_RS02425	COG1475	DNA binding
XOO_RS02430	COG1192	Involved in chromosome partitioning
XOO_RS02445	COG0708	Exodeoxyribonuclease III
XOO_RS02450	COG2211	Major facilitator Superfamily
XOO_RS02465	COG0739	heme binding
XOO_RS02505	COG2963	transposase activity
XOO_RS02515	COG0745	RESPONSE REGULATOR receiver
XOO_RS02555	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XOO_RS02575	COG2814	Major facilitator Superfamily
XOO_RS02590	COG1289	transmembrane transporter activity
XOO_RS02600	COG0577	efflux transmembrane transporter activity
XOO_RS02600	COG1136	(ABC) transporter
XOO_RS02605	COG0151	Belongs to the GarS family
XOO_RS02620	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XOO_RS02625	COG2267	carboxylic ester hydrolase activity
XOO_RS02635	COG2267	carboxylic ester hydrolase activity
XOO_RS02640	COG2453	phosphatase
XOO_RS02640	COG0671	phosphoesterase, PA-phosphatase related
XOO_RS02650	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XOO_RS02685	COG0439	Biotin carboxylase
XOO_RS02695	COG0511	ligase activity, forming carbon-carbon bonds
XOO_RS02715	COG1324	tolerance protein
XOO_RS02735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XOO_RS02755	COG0534	Mate efflux family protein
XOO_RS02760	COG0616	signal peptide processing
XOO_RS02770	COG1028	Short-chain dehydrogenase reductase Sdr
XOO_RS02785	COG0009	L-threonylcarbamoyladenylate synthase
XOO_RS02790	COG1754	DNA topoisomerase type I activity
XOO_RS02790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XOO_RS02805	COG2922	Belongs to the Smg family
XOO_RS02810	COG0758	DNA mediated transformation
XOO_RS02815	COG1652	LysM domain
XOO_RS02820	COG0242	peptide deformylase activity
XOO_RS02825	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XOO_RS02830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XOO_RS02830	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XOO_RS02875	COG1560	Kdo2-lipid A biosynthetic process
XOO_RS02885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XOO_RS03090	COG1063	alcohol dehydrogenase
XOO_RS03100	COG1294	oxidase, subunit
XOO_RS03105	COG1271	oxidase subunit
XOO_RS03135	COG2963	transposase activity
XOO_RS03140	COG2801	Transposase and inactivated derivatives
XOO_RS03170	COG3279	Response regulator of the LytR AlgR family
XOO_RS03175	COG3279	Response regulator of the LytR AlgR family
XOO_RS03190	COG0531	amino acid
XOO_RS03205	COG3590	peptidase
XOO_RS03220	COG0667	Aldo Keto reductase
XOO_RS03250	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XOO_RS03275	COG0025	NhaP-type Na H and K H
XOO_RS03280	COG1131	(ABC) transporter
XOO_RS03285	COG0842	Transport permease protein
XOO_RS03300	COG1404	Belongs to the peptidase S8 family
XOO_RS03315	COG0745	RESPONSE REGULATOR receiver
XOO_RS03360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XOO_RS03385	COG2205	protein histidine kinase activity
XOO_RS03385	COG2202	Pas domain
XOO_RS03405	COG2813	Specifically methylates the guanine in position
XOO_RS03410	COG1187	pseudouridine synthase activity
XOO_RS03415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XOO_RS03450	COG0697	spore germination
XOO_RS03460	COG2011	ABC-type metal ion transport system permease component
XOO_RS03490	COG0508	dehydrogenase complex catalyzes the overall conversion of
XOO_RS03500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XOO_RS03520	COG0356	it plays a direct role in the translocation of protons across the membrane
XOO_RS03530	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XOO_RS03540	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XOO_RS03545	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XOO_RS03550	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XOO_RS03555	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XOO_RS03600	COG3842	ATPase activity
XOO_RS03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XOO_RS03610	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XOO_RS03630	COG3039	Transposase
XOO_RS03675	COG0339	signal peptide processing
XOO_RS03710	COG1956	GAF domain-containing protein
XOO_RS03715	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XOO_RS03725	COG0720	synthase
XOO_RS03735	COG0513	Belongs to the DEAD box helicase family
XOO_RS03775	COG0626	cystathionine gamma-synthase activity
XOO_RS03810	COG3328	transposase activity
XOO_RS03835	COG2086	electron transfer activity
XOO_RS03860	COG0662	Cupin 2, conserved barrel domain protein
XOO_RS03860	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XOO_RS03865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XOO_RS03900	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XOO_RS03900	COG3218	ABC-type transport auxiliary lipoprotein component
XOO_RS03905	COG1127	ABC transporter
XOO_RS03910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XOO_RS03925	COG0442	prolyl-tRNA aminoacylation
XOO_RS03935	COG1183	phosphatidylcholine synthase activity
XOO_RS04000	COG2801	Transposase and inactivated derivatives
XOO_RS04005	COG2963	transposase activity
XOO_RS04015	COG0525	valine-tRNA ligase activity
XOO_RS04030	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XOO_RS04040	COG0795	lipopolysaccharide-transporting ATPase activity
XOO_RS04055	COG4974	Belongs to the 'phage' integrase family
XOO_RS04060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XOO_RS04065	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XOO_RS04065	COG0047	phosphoribosylformylglycinamidine synthase activity
XOO_RS04070	COG5295	Hep Hag repeat protein
XOO_RS04080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XOO_RS04090	COG1459	type II secretion system
XOO_RS04095	COG2165	general secretion pathway protein
XOO_RS04100	COG4970	Tfp pilus assembly protein FimT
XOO_RS04105	COG2165	general secretion pathway protein
XOO_RS04110	COG4795	General secretion pathway protein
XOO_RS04115	COG3156	type II secretion system protein K
XOO_RS04120	COG3166	PFAM Fimbrial assembly family protein
XOO_RS04135	COG1450	Type ii and iii secretion system protein
XOO_RS04145	COG2188	Transcriptional regulator
XOO_RS04180	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
XOO_RS04185	COG1518	maintenance of DNA repeat elements
XOO_RS04225	COG1399	metal-binding, possibly nucleic acid-binding protein
XOO_RS04250	COG1028	Short-chain dehydrogenase reductase Sdr
XOO_RS04255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XOO_RS04265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XOO_RS04270	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XOO_RS04310	COG3829	transcription factor binding
XOO_RS04370	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS04380	COG0678	peroxiredoxin activity
XOO_RS04400	COG0330	HflC and HflK could
XOO_RS04405	COG0330	HflC and HflK could
XOO_RS04420	COG0308	aminopeptidase N
XOO_RS04460	COG1560	Kdo2-lipid A biosynthetic process
XOO_RS04465	COG1519	Transferase
XOO_RS04470	COG1538	Outer membrane efflux protein
XOO_RS04475	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XOO_RS04510	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XOO_RS04515	COG0066	3-isopropylmalate dehydratase activity
XOO_RS04550	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XOO_RS04560	COG3710	Transcriptional regulator
XOO_RS04580	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XOO_RS04620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XOO_RS04630	COG3781	membrane
XOO_RS04645	COG0625	glutathione transferase activity
XOO_RS04655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XOO_RS04660	COG1217	gtp-binding protein TYPA
XOO_RS04680	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XOO_RS04700	COG2963	transposase activity
XOO_RS04705	COG2801	Transposase and inactivated derivatives
XOO_RS04750	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS04780	COG2963	transposase activity
XOO_RS04810	COG3293	Transposase
XOO_RS04855	COG3293	Transposase
XOO_RS04860	COG0584	glycerophosphoryl diester phosphodiesterase
XOO_RS04890	COG0473	3-isopropylmalate dehydrogenase activity
XOO_RS04920	COG2963	transposase activity
XOO_RS04945	COG0544	peptidyl-prolyl cis-trans isomerase activity
XOO_RS04985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XOO_RS05010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XOO_RS05020	COG3293	Transposase
XOO_RS05025	COG0631	protein serine/threonine phosphatase activity
XOO_RS05095	COG0582	viral genome integration into host DNA
XOO_RS05105	COG0859	PFAM glycosyl transferase family 9
XOO_RS05110	COG3642	lipopolysaccharide core region biosynthetic process
XOO_RS05115	COG1234	tRNA 3'-trailer cleavage
XOO_RS05120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XOO_RS05130	COG0315	cyclic pyranopterin monophosphate synthase activity
XOO_RS05135	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XOO_RS05140	COG0314	molybdopterin synthase activity
XOO_RS05165	COG0537	adenosine 5'-monophosphoramidase activity
XOO_RS05185	COG0714	Associated with various cellular activities
XOO_RS05205	COG0242	peptide deformylase activity
XOO_RS05260	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XOO_RS05265	COG0726	polysaccharide deacetylase
XOO_RS05310	COG2211	Major facilitator Superfamily
XOO_RS05315	COG1609	Transcriptional regulator
XOO_RS05320	COG1028	Short-chain dehydrogenase reductase Sdr
XOO_RS05325	COG2851	Citrate transporter
XOO_RS05340	COG0642	Histidine kinase
XOO_RS05350	COG2197	response regulator
XOO_RS05375	COG0583	DNA-binding transcription factor activity
XOO_RS05390	COG4191	Histidine kinase
XOO_RS05405	COG0281	malic enzyme
XOO_RS05405	COG0280	phosphate acetyltransferase
XOO_RS05415	COG2963	transposase activity
XOO_RS05420	COG2801	Transposase and inactivated derivatives
XOO_RS05440	COG0352	thiamine-phosphate diphosphorylase activity
XOO_RS05445	COG1773	rubredoxin
XOO_RS05450	COG2912	Transglutaminase-like superfamily
XOO_RS05460	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XOO_RS05470	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XOO_RS05490	COG0006	proline dipeptidase activity
XOO_RS05505	COG3293	Transposase
XOO_RS05525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XOO_RS05540	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XOO_RS05545	COG1561	YicC-like family, N-terminal region
XOO_RS05565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XOO_RS05575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XOO_RS05600	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XOO_RS05645	COG0714	Associated with various cellular activities
XOO_RS05665	COG2304	oxidoreductase activity
XOO_RS05680	COG1301	dicarboxylic acid transport
XOO_RS05685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XOO_RS05690	COG4773	Receptor
XOO_RS05695	COG0739	heme binding
XOO_RS05700	COG1376	ErfK ybiS ycfS ynhG family protein
XOO_RS05735	COG1028	Short-chain dehydrogenase reductase Sdr
XOO_RS05750	COG0642	Histidine kinase
XOO_RS05770	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XOO_RS05775	COG4149	molybdate abc transporter
XOO_RS05780	COG0725	ABC transporter, periplasmic molybdate-binding protein
XOO_RS05785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XOO_RS05785	COG3453	Protein conserved in bacteria
XOO_RS05820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XOO_RS05825	COG3293	Transposase
XOO_RS05840	COG2205	protein histidine kinase activity
XOO_RS05845	COG0745	RESPONSE REGULATOR receiver
XOO_RS05860	COG3039	Transposase
XOO_RS05895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XOO_RS05900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XOO_RS05935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XOO_RS05975	COG2801	Transposase and inactivated derivatives
XOO_RS06020	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XOO_RS06030	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XOO_RS06035	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XOO_RS06050	COG1842	Phage shock protein A
XOO_RS06075	COG0754	glutathionylspermidine amidase activity
XOO_RS06150	COG0531	amino acid
XOO_RS06155	COG2197	response regulator
XOO_RS06165	COG1113	amino acid transport
XOO_RS06180	COG1271	oxidase subunit
XOO_RS06185	COG1294	oxidase, subunit
XOO_RS06195	COG2239	Acts as a magnesium transporter
XOO_RS06200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XOO_RS06205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XOO_RS06215	COG1660	Displays ATPase and GTPase activities
XOO_RS06220	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XOO_RS06240	COG1137	ATPase activity
XOO_RS06245	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XOO_RS06255	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XOO_RS06265	COG0271	Belongs to the BolA IbaG family
XOO_RS06270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XOO_RS06290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XOO_RS06305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XOO_RS06315	COG0628	permease
XOO_RS06325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XOO_RS06330	COG3178	'Phosphotransferase
XOO_RS06355	COG1555	photosystem II stabilization
XOO_RS06405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XOO_RS06420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XOO_RS06440	COG0228	four-way junction DNA binding
XOO_RS06445	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XOO_RS06450	COG0336	Belongs to the RNA methyltransferase TrmD family
XOO_RS06460	COG0534	Mate efflux family protein
XOO_RS06490	COG0542	response to heat
XOO_RS06505	COG2963	transposase activity
XOO_RS06520	COG4206	TonB-dependent receptor
XOO_RS06570	COG0019	diaminopimelate decarboxylase activity
XOO_RS06580	COG2814	Major facilitator Superfamily
XOO_RS06585	COG4264	IucA IucC family
XOO_RS06595	COG4772	TonB-dependent receptor
XOO_RS06605	COG2801	Transposase and inactivated derivatives
XOO_RS06610	COG4651	solute:proton antiporter activity
XOO_RS06610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XOO_RS06640	COG0488	(ABC) transporter
XOO_RS06665	COG0657	acetylesterase activity
XOO_RS06665	COG2755	lipolytic protein G-D-S-L family
XOO_RS06685	COG3293	Transposase
XOO_RS06695	COG3039	Transposase
XOO_RS06705	COG2207	Transcriptional regulator
XOO_RS06710	COG0326	Molecular chaperone. Has ATPase activity
XOO_RS06730	COG2963	transposase activity
XOO_RS06740	COG3328	transposase activity
XOO_RS06760	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XOO_RS06780	COG2963	transposase activity
XOO_RS06785	COG3039	Transposase
XOO_RS06790	COG2146	nitrite reductase [NAD(P)H] activity
XOO_RS06800	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XOO_RS06805	COG0719	Fe-S assembly protein
XOO_RS06810	COG0396	ATPase activity
XOO_RS06815	COG0719	Fe-S assembly protein
XOO_RS06820	COG1959	2 iron, 2 sulfur cluster binding
XOO_RS06835	COG0693	protein deglycase activity
XOO_RS06875	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XOO_RS06900	COG0519	Catalyzes the synthesis of GMP from XMP
XOO_RS06915	COG1678	Uncharacterized ACR, COG1678
XOO_RS06920	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XOO_RS06930	COG1764	response to oxidative stress
XOO_RS06940	COG0384	phenazine biosynthesis protein PhzF
XOO_RS06945	COG0384	phenazine biosynthesis protein PhzF
XOO_RS06955	COG0527	aspartate kinase activity
XOO_RS06985	COG0142	geranyltranstransferase activity
XOO_RS06990	COG0629	single-stranded DNA binding
XOO_RS06995	COG5001	Diguanylate cyclase
XOO_RS06995	COG4251	negative regulation of phosphorylation
XOO_RS06995	COG3706	GGDEF domain
XOO_RS06995	COG2203	Gaf domain
XOO_RS07000	COG3321	synthase
XOO_RS07000	COG1028	Short-chain dehydrogenase reductase Sdr
XOO_RS07000	COG0604	alcohol dehydrogenase
XOO_RS07025	COG2879	small protein
XOO_RS07030	COG1966	Carbon starvation protein
XOO_RS07035	COG1741	Belongs to the pirin family
XOO_RS07105	COG1741	Belongs to the pirin family
XOO_RS07115	COG1515	deoxyribonuclease V activity
XOO_RS07130	COG3590	peptidase
XOO_RS07145	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XOO_RS07150	COG2202	Pas domain
XOO_RS07150	COG2200	EAL domain
XOO_RS07150	COG2199	diguanylate cyclase activity
XOO_RS07155	COG0835	chemotaxis
XOO_RS07160	COG0840	transmembrane signaling receptor activity
XOO_RS07165	COG2198	Histidine kinase
XOO_RS07165	COG0643	Histidine kinase
XOO_RS07175	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XOO_RS07185	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XOO_RS07240	COG3039	Transposase
XOO_RS07285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XOO_RS07290	COG0735	belongs to the Fur family
XOO_RS07330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XOO_RS07335	COG0084	hydrolase, TatD family'
XOO_RS07350	COG1960	acyl-CoA dehydrogenase activity
XOO_RS07375	COG0367	asparagine synthase
XOO_RS07385	COG0305	Participates in initiation and elongation during chromosome replication
XOO_RS07390	COG0415	Belongs to the DNA photolyase family
XOO_RS07405	COG1028	Short-chain dehydrogenase reductase Sdr
XOO_RS07515	COG5001	Diguanylate cyclase
XOO_RS07515	COG5002	protein histidine kinase activity
XOO_RS07520	COG1187	pseudouridine synthase activity
XOO_RS07535	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XOO_RS07545	COG0475	glutathione-regulated potassium exporter activity
XOO_RS07550	COG5002	protein histidine kinase activity
XOO_RS07550	COG5000	phosphorelay sensor kinase activity
XOO_RS07555	COG0745	RESPONSE REGULATOR receiver
XOO_RS07585	COG1132	(ABC) transporter
XOO_RS07605	COG3293	Transposase
XOO_RS07625	COG3039	Transposase
XOO_RS07635	COG3039	Transposase
XOO_RS07640	COG3209	COG3209 Rhs family protein
XOO_RS07665	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XOO_RS07675	COG4969	Belongs to the N-Me-Phe pilin family
XOO_RS07680	COG2194	sulfuric ester hydrolase activity
XOO_RS07700	COG2184	nucleotidyltransferase activity
XOO_RS07720	COG0045	succinate-CoA ligase (ADP-forming) activity
XOO_RS07725	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XOO_RS07735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XOO_RS07735	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XOO_RS07740	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XOO_RS07745	COG0564	pseudouridine synthase activity
XOO_RS07770	COG3387	PFAM Glycoside hydrolase 15-related
XOO_RS07775	COG1877	trehalose-phosphatase activity
XOO_RS07830	COG1595	DNA-templated transcription, initiation
XOO_RS07840	COG1946	Acyl-CoA thioesterase
XOO_RS07855	COG0824	Thioesterase
XOO_RS07870	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XOO_RS07875	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XOO_RS07880	COG0268	Binds directly to 16S ribosomal RNA
XOO_RS07885	COG0728	peptidoglycan biosynthetic process
XOO_RS07890	COG0196	riboflavin kinase activity
XOO_RS07900	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XOO_RS07905	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XOO_RS07920	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XOO_RS07925	COG1845	cytochrome c oxidase, subunit III
XOO_RS07930	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XOO_RS07950	COG3209	COG3209 Rhs family protein
XOO_RS07950	COG3209	COG3209 Rhs family protein
XOO_RS07990	COG2963	transposase activity
XOO_RS07995	COG2801	Transposase and inactivated derivatives
XOO_RS08020	COG2801	Transposase and inactivated derivatives
XOO_RS08025	COG2963	transposase activity
XOO_RS08040	COG2963	transposase activity
XOO_RS08095	COG0632	four-way junction helicase activity
XOO_RS08105	COG2255	four-way junction helicase activity
XOO_RS08110	COG0824	Thioesterase
XOO_RS08120	COG0848	biopolymer transport protein
XOO_RS08135	COG2885	chlorophyll binding
XOO_RS08145	COG0602	queuosine metabolic process
XOO_RS08165	COG3293	Transposase
XOO_RS08175	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XOO_RS08340	COG3179	chitinase
XOO_RS08385	COG4695	Portal protein
XOO_RS08450	COG0514	ATP-dependent DNA helicase (RecQ)
XOO_RS08455	COG0783	Belongs to the Dps family
XOO_RS08460	COG1643	Atp-dependent helicase
XOO_RS08485	COG0837	glucose binding
XOO_RS08520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XOO_RS08530	COG1215	transferase activity, transferring glycosyl groups
XOO_RS08535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XOO_RS08545	COG1199	ATP-dependent helicase activity
XOO_RS08555	COG1397	ADP-ribosylglycohydrolase
XOO_RS08565	COG0189	ligase activity
XOO_RS08580	COG0835	chemotaxis
XOO_RS08585	COG0840	transmembrane signaling receptor activity
XOO_RS08620	COG2304	oxidoreductase activity
XOO_RS08635	COG1446	asparaginase
XOO_RS08640	COG3142	Participates in the control of copper homeostasis
XOO_RS08680	COG3537	Alpha-1,2-mannosidase
XOO_RS08700	COG3039	Transposase
XOO_RS08735	COG1472	Belongs to the glycosyl hydrolase 3 family
XOO_RS08745	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XOO_RS08750	COG3858	chitin binding
XOO_RS08750	COG1388	LysM domain
XOO_RS08765	COG0837	glucose binding
XOO_RS08770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XOO_RS08780	COG0494	nUDIX hydrolase
XOO_RS08790	COG3956	TIGRFAM MazG family protein
XOO_RS08800	COG0330	HflC and HflK could
XOO_RS08815	COG0509	glycine decarboxylation via glycine cleavage system
XOO_RS08850	COG1309	transcriptional regulator
XOO_RS08855	COG4771	TonB-dependent receptor
XOO_RS08865	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XOO_RS08875	COG0463	Glycosyl transferase, family 2
XOO_RS08880	COG0516	GMP reductase activity
XOO_RS08880	COG0517	IMP dehydrogenase activity
XOO_RS08890	COG1272	protein, Hemolysin III
XOO_RS08895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XOO_RS08900	COG0739	heme binding
XOO_RS08905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XOO_RS08910	COG0626	cystathionine gamma-synthase activity
XOO_RS08920	COG1760	l-serine dehydratase
XOO_RS08930	COG2353	YceI-like domain
XOO_RS08940	COG2353	YceI-like domain
XOO_RS08955	COG0745	RESPONSE REGULATOR receiver
XOO_RS08955	COG2205	protein histidine kinase activity
XOO_RS08955	COG3292	Two component regulator propeller
XOO_RS08960	COG3039	Transposase
XOO_RS09000	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XOO_RS09025	COG1960	acyl-CoA dehydrogenase activity
XOO_RS09030	COG1024	Enoyl-CoA hydratase
XOO_RS09050	COG1024	Enoyl-CoA hydratase
XOO_RS09050	COG1250	3-hydroxyacyl-CoA dehydrogenase
XOO_RS09065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XOO_RS09095	COG1381	Involved in DNA repair and RecF pathway recombination
XOO_RS09110	COG2954	triphosphatase activity
XOO_RS09125	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XOO_RS09130	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XOO_RS09135	COG3046	protein related to deoxyribodipyrimidine photolyase
XOO_RS09145	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XOO_RS09150	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XOO_RS09155	COG1278	Cold shock
XOO_RS09170	COG1201	RNA secondary structure unwinding
XOO_RS09175	COG1793	dna ligase
XOO_RS09185	COG1793	dna ligase
XOO_RS09185	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XOO_RS09215	COG0183	Belongs to the thiolase family
XOO_RS09230	COG1451	nucleotide metabolic process
XOO_RS09245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XOO_RS09295	COG2824	Alkylphosphonate utilization operon protein PhnA
XOO_RS09310	COG1902	pentaerythritol trinitrate reductase activity
XOO_RS09315	COG2814	Major facilitator Superfamily
XOO_RS09345	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XOO_RS09345	COG0392	lysyltransferase activity
XOO_RS09355	COG0251	oxidation-reduction process
XOO_RS09360	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XOO_RS09375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XOO_RS09400	COG1595	DNA-templated transcription, initiation
XOO_RS09420	COG2878	Part of a membrane complex involved in electron transport
XOO_RS09430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XOO_RS09430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XOO_RS09440	COG0346	lactoylglutathione lyase activity
XOO_RS09450	COG0833	amino acid
XOO_RS09455	COG2040	homocysteine
XOO_RS09465	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XOO_RS09530	COG1981	membrane
XOO_RS09555	COG1131	(ABC) transporter
XOO_RS09560	COG4771	TonB-dependent receptor
XOO_RS09570	COG0825	malonyl-CoA metabolic process
XOO_RS09590	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XOO_RS09595	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XOO_RS09610	COG0750	zinc metalloprotease
XOO_RS09620	COG0575	Belongs to the CDS family
XOO_RS09630	COG0233	cytoplasmic translational termination
XOO_RS09645	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XOO_RS09705	COG1393	Belongs to the ArsC family
XOO_RS09720	COG0367	asparagine synthase
XOO_RS09735	COG4774	siderophore transport
XOO_RS09755	COG2207	Transcriptional regulator
XOO_RS09770	COG1566	PFAM secretion protein HlyD family protein
XOO_RS09775	COG2814	Major facilitator Superfamily
XOO_RS09815	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS09835	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XOO_RS09845	COG1960	acyl-CoA dehydrogenase activity
XOO_RS09865	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XOO_RS09875	COG2914	Belongs to the UPF0125 (RnfH) family
XOO_RS09880	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XOO_RS09890	COG0497	DNA recombination
XOO_RS09900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XOO_RS09910	COG0484	heat shock protein binding
XOO_RS09915	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XOO_RS09920	COG1605	Chorismate mutase
XOO_RS09920	COG0287	Prephenate dehydrogenase
XOO_RS09935	COG0583	DNA-binding transcription factor activity
XOO_RS09940	COG1132	(ABC) transporter
XOO_RS09975	COG2850	peptidyl-arginine hydroxylation
XOO_RS10015	COG3293	Transposase
XOO_RS10065	COG1131	(ABC) transporter
XOO_RS10070	COG1725	Transcriptional regulator
XOO_RS10075	COG0386	Belongs to the glutathione peroxidase family
XOO_RS10090	COG2900	Belongs to the SlyX family
XOO_RS10105	COG1609	Transcriptional regulator
XOO_RS10115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XOO_RS10125	COG1410	methionine synthase
XOO_RS10125	COG0646	methionine synthase
XOO_RS10130	COG1410	methionine synthase
XOO_RS10130	COG0646	methionine synthase
XOO_RS10135	COG2226	methyltransferase
XOO_RS10140	COG1960	acyl-CoA dehydrogenase activity
XOO_RS10160	COG0557	exoribonuclease II activity
XOO_RS10180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XOO_RS10190	COG3039	Transposase
XOO_RS10205	COG3328	transposase activity
XOO_RS10215	COG1278	Cold shock
XOO_RS10230	COG3039	Transposase
XOO_RS10235	COG3039	Transposase
XOO_RS10295	COG2801	Transposase and inactivated derivatives
XOO_RS10300	COG2963	transposase activity
XOO_RS10330	COG3039	Transposase
XOO_RS10340	COG0583	DNA-binding transcription factor activity
XOO_RS10390	COG2201	protein-glutamate methylesterase activity
XOO_RS10415	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XOO_RS10425	COG0531	amino acid
XOO_RS10430	COG0531	amino acid
XOO_RS10440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XOO_RS10445	COG0277	FAD linked oxidase domain protein
XOO_RS10510	COG0436	Aminotransferase
XOO_RS10535	COG1187	pseudouridine synthase activity
XOO_RS10540	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XOO_RS10545	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XOO_RS10550	COG2350	Protein conserved in bacteria
XOO_RS10590	COG1175	transmembrane transport
XOO_RS10595	COG0395	ABC-type sugar transport system, permease component
XOO_RS10620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XOO_RS10625	COG2957	Belongs to the agmatine deiminase family
XOO_RS10640	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XOO_RS10645	COG0539	negative regulation of cytoplasmic translation
XOO_RS10650	COG0776	regulation of translation
XOO_RS10660	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XOO_RS10665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XOO_RS10675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XOO_RS10680	COG0475	glutathione-regulated potassium exporter activity
XOO_RS10680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XOO_RS10715	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XOO_RS10735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XOO_RS10740	COG0583	DNA-binding transcription factor activity
XOO_RS10745	COG1028	Short-chain dehydrogenase reductase Sdr
XOO_RS10760	COG0583	DNA-binding transcription factor activity
XOO_RS10765	COG0583	DNA-binding transcription factor activity
XOO_RS10780	COG1914	H( )-stimulated, divalent metal cation uptake system
XOO_RS10800	COG0668	transmembrane transport
XOO_RS10835	COG3039	Transposase
XOO_RS10845	COG1028	Short-chain dehydrogenase reductase Sdr
XOO_RS10850	COG1183	phosphatidylcholine synthase activity
XOO_RS10860	COG3243	poly(R)-hydroxyalkanoic acid synthase
XOO_RS10875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XOO_RS10875	COG0723	plastoquinol--plastocyanin reductase activity
XOO_RS10885	COG2183	response to ionizing radiation
XOO_RS10895	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XOO_RS10910	COG0671	phosphoesterase, PA-phosphatase related
XOO_RS10925	COG1794	racemase activity, acting on amino acids and derivatives
XOO_RS10930	COG0697	spore germination
XOO_RS10955	COG1012	belongs to the aldehyde dehydrogenase family
XOO_RS10990	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XOO_RS11000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XOO_RS11005	COG0124	histidyl-tRNA synthetase
XOO_RS11020	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XOO_RS11035	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XOO_RS11035	COG0131	Imidazoleglycerol-phosphate dehydratase
XOO_RS11045	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XOO_RS11055	COG0140	phosphoribosyl-ATP diphosphatase activity
XOO_RS11055	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XOO_RS11130	COG3293	Transposase
XOO_RS11150	COG3293	Transposase
XOO_RS11175	COG3293	Transposase
XOO_RS11195	COG2201	protein-glutamate methylesterase activity
XOO_RS11205	COG2801	Transposase and inactivated derivatives
XOO_RS11225	COG3039	Transposase
XOO_RS11240	COG3328	transposase activity
XOO_RS11250	COG3039	Transposase
XOO_RS11280	COG0322	excinuclease ABC activity
XOO_RS11290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XOO_RS11300	COG1663	tetraacyldisaccharide 4'-kinase activity
XOO_RS11315	COG0811	peptide transport
XOO_RS11340	COG4591	ABC-type transport system involved in lipoprotein release permease component
XOO_RS11355	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XOO_RS11370	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XOO_RS11380	COG0354	folic acid binding
XOO_RS11390	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XOO_RS11400	COG0363	glucosamine-6-phosphate deaminase activity
XOO_RS11405	COG0129	dihydroxy-acid dehydratase activity
XOO_RS11435	COG2205	protein histidine kinase activity
XOO_RS11435	COG0784	Response regulator, receiver
XOO_RS11435	COG5002	protein histidine kinase activity
XOO_RS11445	COG3293	Transposase
XOO_RS11520	COG0386	Belongs to the glutathione peroxidase family
XOO_RS11605	COG5001	Diguanylate cyclase
XOO_RS11605	COG4251	negative regulation of phosphorylation
XOO_RS11605	COG3706	GGDEF domain
XOO_RS11605	COG2203	Gaf domain
XOO_RS11615	COG1472	Belongs to the glycosyl hydrolase 3 family
XOO_RS11645	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XOO_RS11650	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XOO_RS11660	COG0617	tRNA 3'-terminal CCA addition
XOO_RS11670	COG1469	GTP cyclohydrolase I activity
XOO_RS11675	COG0860	N-Acetylmuramoyl-L-alanine amidase
XOO_RS11685	COG2963	transposase activity
XOO_RS11725	COG4566	intracellular signal transduction
XOO_RS11740	COG3039	Transposase
XOO_RS11745	COG2963	transposase activity
XOO_RS11755	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XOO_RS11760	COG0077	Prephenate dehydratase
XOO_RS11760	COG1605	Chorismate mutase
XOO_RS11770	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XOO_RS11815	COG1228	amidohydrolase
XOO_RS11820	COG2986	histidine ammonia-lyase
XOO_RS11830	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XOO_RS11850	COG2963	transposase activity
XOO_RS11860	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XOO_RS11870	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XOO_RS11885	COG3115	cell septum assembly
XOO_RS11895	COG0359	binds to the 23S rRNA
XOO_RS11905	COG0360	Binds together with S18 to 16S ribosomal RNA
XOO_RS11910	COG0316	Belongs to the HesB IscA family
XOO_RS11945	COG0288	reversible hydration of carbon dioxide
XOO_RS11970	COG2925	Exonuclease
XOO_RS11980	COG0667	Aldo Keto reductase
XOO_RS12010	COG0488	(ABC) transporter
XOO_RS12015	COG4133	protoheme IX ABC transporter activity
XOO_RS12020	COG0488	(ABC) transporter
XOO_RS12055	COG0494	nUDIX hydrolase
XOO_RS12065	COG1024	Enoyl-CoA hydratase
XOO_RS12075	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XOO_RS12095	COG3293	Transposase
XOO_RS12115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XOO_RS12120	COG0573	inorganic phosphate transmembrane transporter activity
XOO_RS12135	COG0704	Plays a role in the regulation of phosphate uptake
XOO_RS12145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XOO_RS12160	COG3328	transposase activity
XOO_RS12190	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XOO_RS12195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XOO_RS12200	COG1862	Preprotein translocase
XOO_RS12205	COG0343	queuine tRNA-ribosyltransferase activity
XOO_RS12260	COG3039	Transposase
XOO_RS12295	COG3293	Transposase
XOO_RS12310	COG0405	Gamma-glutamyltransferase
XOO_RS12315	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XOO_RS12330	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XOO_RS12335	COG0742	ribosomal rna small subunit methyltransferase
XOO_RS12360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XOO_RS12395	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS12420	COG0303	'Molybdopterin
XOO_RS12430	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XOO_RS12440	COG1426	Protein conserved in bacteria
XOO_RS12450	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XOO_RS12465	COG1250	3-hydroxyacyl-CoA dehydrogenase
XOO_RS12465	COG1024	Enoyl-CoA hydratase
XOO_RS12470	COG0183	Belongs to the thiolase family
XOO_RS12475	COG0038	chloride channel
XOO_RS12495	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XOO_RS12515	COG1674	ftsk spoiiie
XOO_RS12520	COG0492	ferredoxin-NADP+ reductase activity
XOO_RS12550	COG0542	response to heat
XOO_RS12565	COG0482	sulfurtransferase activity
XOO_RS12590	COG5001	Diguanylate cyclase
XOO_RS12595	COG4585	Histidine kinase
XOO_RS12605	COG5002	protein histidine kinase activity
XOO_RS12625	COG0784	Response regulator, receiver
XOO_RS12625	COG0835	chemotaxis
XOO_RS12635	COG1558	bacterial-type flagellum-dependent cell motility
XOO_RS12640	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XOO_RS12650	COG4787	bacterial-type flagellum-dependent cell motility
XOO_RS12685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XOO_RS12690	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XOO_RS12720	COG2201	protein-glutamate methylesterase activity
XOO_RS12740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XOO_RS12750	COG1028	Short-chain dehydrogenase reductase Sdr
XOO_RS12780	COG1677	Flagellar hook-basal body complex protein FliE
XOO_RS12830	COG3190	flagellar
XOO_RS12845	COG1684	flagellar biosynthetic protein fliR
XOO_RS12900	COG2198	Histidine kinase
XOO_RS12900	COG0643	Histidine kinase
XOO_RS12900	COG0784	Response regulator, receiver
XOO_RS12915	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS12935	COG3209	COG3209 Rhs family protein
XOO_RS12945	COG3039	Transposase
XOO_RS12955	COG3039	Transposase
XOO_RS13055	COG3039	Transposase
XOO_RS13060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XOO_RS13065	COG4988	ABC transporter
XOO_RS13070	COG1271	oxidase subunit
XOO_RS13080	COG3039	Transposase
XOO_RS13085	COG1271	oxidase subunit
XOO_RS13090	COG1294	oxidase, subunit
XOO_RS13135	COG0165	Argininosuccinate lyase
XOO_RS13150	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XOO_RS13155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XOO_RS13165	COG0137	argininosuccinate synthase activity
XOO_RS13170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XOO_RS13185	COG2166	iron-sulfur cluster assembly
XOO_RS13215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XOO_RS13225	COG4302	ethanolamine ammonia-lyase activity
XOO_RS13230	COG3293	Transposase
XOO_RS13255	COG3039	Transposase
XOO_RS13265	COG4677	pectinesterase activity
XOO_RS13300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XOO_RS13305	COG0402	S-adenosylhomocysteine deaminase activity
XOO_RS13325	COG5001	Diguanylate cyclase
XOO_RS13325	COG3300	MHYT domain
XOO_RS13340	COG0483	inositol monophosphate 1-phosphatase activity
XOO_RS13345	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XOO_RS13365	COG0488	(ABC) transporter
XOO_RS13370	COG0513	Belongs to the DEAD box helicase family
XOO_RS13390	COG0625	glutathione transferase activity
XOO_RS13400	COG1671	Belongs to the UPF0178 family
XOO_RS13405	COG4681	YaeQ
XOO_RS13410	COG2081	HI0933 family
XOO_RS13430	COG1028	Short-chain dehydrogenase reductase Sdr
XOO_RS13450	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XOO_RS13455	COG0860	N-Acetylmuramoyl-L-alanine amidase
XOO_RS13460	COG0802	atpase or kinase
XOO_RS13465	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XOO_RS13465	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XOO_RS13490	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XOO_RS13540	COG3328	transposase activity
XOO_RS13570	COG2969	positive regulation of protein catabolic process
XOO_RS13575	COG0625	glutathione transferase activity
XOO_RS13580	COG2857	Cytochrome c1
XOO_RS13585	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XOO_RS13590	COG0723	plastoquinol--plastocyanin reductase activity
XOO_RS13595	COG0741	lytic transglycosylase activity
XOO_RS13620	COG1702	phosphate starvation-inducible protein PhoH
XOO_RS13640	COG4535	Mg2 and Co2 transporter CorC
XOO_RS13655	COG1012	belongs to the aldehyde dehydrogenase family
XOO_RS13665	COG1177	transmembrane transport
XOO_RS13670	COG1176	ABC-type spermidine putrescine transport system, permease component I
XOO_RS13675	COG3842	ATPase activity
XOO_RS13710	COG0174	glutamine synthetase
XOO_RS13715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XOO_RS13725	COG0477	Major facilitator Superfamily
XOO_RS13735	COG0243	molybdopterin cofactor binding
XOO_RS13745	COG2223	nitrite transmembrane transporter activity
XOO_RS13760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XOO_RS13765	COG1121	(ABC) transporter
XOO_RS13775	COG2733	membrane
XOO_RS13780	COG0784	Response regulator, receiver
XOO_RS13780	COG2205	protein histidine kinase activity
XOO_RS13780	COG5002	protein histidine kinase activity
XOO_RS13790	COG0477	Major facilitator Superfamily
XOO_RS13800	COG3039	Transposase
XOO_RS13805	COG2902	Dehydrogenase
XOO_RS13815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XOO_RS13820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XOO_RS13840	COG1609	Transcriptional regulator
XOO_RS13845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XOO_RS13845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XOO_RS13850	COG1105	Belongs to the carbohydrate kinase PfkB family
XOO_RS13855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XOO_RS13855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XOO_RS13870	COG3039	Transposase
XOO_RS13930	COG3039	Transposase
XOO_RS13950	COG4771	TonB-dependent receptor
XOO_RS13960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XOO_RS13980	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XOO_RS13985	COG1360	Flagellar Motor Protein
XOO_RS13995	COG0835	chemotaxis
XOO_RS14005	COG0745	RESPONSE REGULATOR receiver
XOO_RS14035	COG0840	transmembrane signaling receptor activity
XOO_RS14045	COG0840	transmembrane signaling receptor activity
XOO_RS14050	COG0840	transmembrane signaling receptor activity
XOO_RS14055	COG0840	transmembrane signaling receptor activity
XOO_RS14060	COG0840	transmembrane signaling receptor activity
XOO_RS14065	COG0840	transmembrane signaling receptor activity
XOO_RS14120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XOO_RS14150	COG0318	PFAM AMP-dependent synthetase and ligase
XOO_RS14155	COG1024	Enoyl-CoA hydratase
XOO_RS14160	COG2205	protein histidine kinase activity
XOO_RS14160	COG0784	Response regulator, receiver
XOO_RS14160	COG2198	Histidine kinase
XOO_RS14180	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XOO_RS14220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XOO_RS14230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XOO_RS14235	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XOO_RS14245	COG0505	Belongs to the CarA family
XOO_RS14260	COG3293	Transposase
XOO_RS14265	COG2258	MOSC domain
XOO_RS14270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XOO_RS14320	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XOO_RS14340	COG0477	Major facilitator Superfamily
XOO_RS14350	COG1070	Carbohydrate kinase
XOO_RS14365	COG1501	Belongs to the glycosyl hydrolase 31 family
XOO_RS14380	COG0800	Aldolase
XOO_RS14385	COG4948	Mandelate Racemase Muconate Lactonizing
XOO_RS14395	COG3734	2-keto-3-deoxy-galactonokinase
XOO_RS14400	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XOO_RS14410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XOO_RS14425	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XOO_RS14430	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XOO_RS14440	COG0351	phosphomethylpyrimidine kinase
XOO_RS14470	COG0583	DNA-binding transcription factor activity
XOO_RS14475	COG1741	Belongs to the pirin family
XOO_RS14495	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XOO_RS14500	COG0305	Participates in initiation and elongation during chromosome replication
XOO_RS14520	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XOO_RS14525	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XOO_RS14530	COG2137	regulation of response to DNA damage stimulus
XOO_RS14535	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XOO_RS14550	COG1546	Belongs to the CinA family
XOO_RS14555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XOO_RS14570	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XOO_RS14580	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XOO_RS14585	COG1534	Rna-binding protein
XOO_RS14600	COG1238	metal cluster binding
XOO_RS14605	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XOO_RS14610	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XOO_RS14615	COG2840	Smr protein MutS2
XOO_RS14625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XOO_RS14630	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XOO_RS14635	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XOO_RS14640	COG0148	phosphopyruvate hydratase activity
XOO_RS14650	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XOO_RS14655	COG0504	CTP synthase activity
XOO_RS14690	COG0306	phosphate transporter
XOO_RS14700	COG1253	flavin adenine dinucleotide binding
XOO_RS14715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XOO_RS14720	COG0477	Major facilitator Superfamily
XOO_RS14725	COG1132	(ABC) transporter
XOO_RS14730	COG1136	(ABC) transporter
XOO_RS14745	COG0438	transferase activity, transferring glycosyl groups
XOO_RS14755	COG2264	protein methyltransferase activity
XOO_RS14785	COG2244	polysaccharide biosynthetic process
XOO_RS14835	COG1595	DNA-templated transcription, initiation
XOO_RS14850	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XOO_RS14870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XOO_RS14930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XOO_RS14935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XOO_RS14970	COG2963	transposase activity
XOO_RS14985	COG4644	lycopene metabolic process
XOO_RS14995	COG1858	cytochrome C peroxidase
XOO_RS15020	COG0515	serine threonine protein kinase
XOO_RS15025	COG0631	protein serine/threonine phosphatase activity
XOO_RS15070	COG3039	Transposase
XOO_RS15125	COG3039	Transposase
XOO_RS15150	COG2801	Transposase and inactivated derivatives
XOO_RS15155	COG3039	Transposase
XOO_RS15180	COG0428	transporter
XOO_RS15185	COG0428	transporter
XOO_RS15190	COG3064	Membrane
XOO_RS15210	COG3293	Transposase
XOO_RS15220	COG1054	Belongs to the UPF0176 family
XOO_RS15240	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XOO_RS15275	COG3039	Transposase
XOO_RS15315	COG1648	precorrin-2 dehydrogenase activity
XOO_RS15315	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XOO_RS15340	COG0746	molybdenum cofactor guanylyltransferase activity
XOO_RS15385	COG3328	transposase activity
XOO_RS15390	COG4206	TonB-dependent receptor
XOO_RS15415	COG4206	TonB-dependent receptor
XOO_RS15465	COG0531	amino acid
XOO_RS15480	COG0006	proline dipeptidase activity
XOO_RS15490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XOO_RS15505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XOO_RS15510	COG3938	Belongs to the proline racemase family
XOO_RS15520	COG0552	protein localization to endoplasmic reticulum
XOO_RS15560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XOO_RS15670	COG0438	transferase activity, transferring glycosyl groups
XOO_RS15680	COG0438	transferase activity, transferring glycosyl groups
XOO_RS15685	COG0438	transferase activity, transferring glycosyl groups
XOO_RS15755	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XOO_RS15770	COG2963	transposase activity
XOO_RS15790	COG0556	nucleotide-excision repair
XOO_RS15795	COG4969	Belongs to the N-Me-Phe pilin family
XOO_RS15820	COG3039	Transposase
XOO_RS15850	COG1611	Belongs to the LOG family
XOO_RS15860	COG2095	MarC family integral membrane protein
XOO_RS15870	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XOO_RS15905	COG1185	polyribonucleotide nucleotidyltransferase activity
XOO_RS15910	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XOO_RS15930	COG0195	Participates in both transcription termination and antitermination
XOO_RS15935	COG0779	Required for maturation of 30S ribosomal subunits
XOO_RS15945	COG1007	ATP synthesis coupled electron transport
XOO_RS15975	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XOO_RS15980	COG1034	ATP synthesis coupled electron transport
XOO_RS15985	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XOO_RS15990	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XOO_RS15995	COG0649	NAD binding
XOO_RS16000	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XOO_RS16010	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XOO_RS16025	COG0149	triose-phosphate isomerase activity
XOO_RS16045	COG3293	Transposase
XOO_RS16075	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XOO_RS16080	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XOO_RS16105	COG0135	phosphoribosylanthranilate isomerase activity
XOO_RS16110	COG0101	tRNA pseudouridine synthase activity
XOO_RS16125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XOO_RS16130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XOO_RS16135	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XOO_RS16140	COG2890	protein-(glutamine-N5) methyltransferase activity
XOO_RS16160	COG0433	COG0433 Predicted ATPase
XOO_RS16165	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS16180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XOO_RS16190	COG0412	Dienelactone hydrolase
XOO_RS16210	COG0717	Belongs to the dCTP deaminase family
XOO_RS16215	COG0489	protein tyrosine kinase activity
XOO_RS16250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XOO_RS16255	COG2311	Membrane
XOO_RS16260	COG1047	Peptidyl-prolyl cis-trans
XOO_RS16265	COG0791	NLP P60 protein
XOO_RS16270	COG0791	NLP P60 protein
XOO_RS16285	COG1301	dicarboxylic acid transport
XOO_RS16290	COG1785	Belongs to the alkaline phosphatase family
XOO_RS16295	COG0037	tRNA processing
XOO_RS16300	COG1722	exodeoxyribonuclease VII activity
XOO_RS16305	COG0142	geranyltranstransferase activity
XOO_RS16325	COG0312	modulator of DNA gyrase
XOO_RS16335	COG0312	modulator of DNA gyrase
XOO_RS16380	COG2968	Membrane
XOO_RS16400	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XOO_RS16425	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XOO_RS16450	COG3118	belongs to the thioredoxin family
XOO_RS16465	COG3293	Transposase
XOO_RS16515	COG3293	Transposase
XOO_RS16535	COG3039	Transposase
XOO_RS16565	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS16630	COG2022	thiamine diphosphate biosynthetic process
XOO_RS16640	COG3273	potassium ion transport
XOO_RS16640	COG0471	metal ion transport
XOO_RS16670	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS16680	COG1970	mechanosensitive ion channel activity
XOO_RS16690	COG3293	Transposase
XOO_RS16700	COG2272	Belongs to the type-B carboxylesterase lipase family
XOO_RS16705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XOO_RS16730	COG0308	aminopeptidase N
XOO_RS16735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XOO_RS16745	COG0529	Catalyzes the synthesis of activated sulfate
XOO_RS16745	COG2895	sulfate adenylyltransferase (ATP) activity
XOO_RS16750	COG0175	sulfate reduction
XOO_RS16760	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XOO_RS16765	COG0175	sulfate reduction
XOO_RS16785	COG2205	protein histidine kinase activity
XOO_RS16785	COG2198	Histidine kinase
XOO_RS16785	COG0784	Response regulator, receiver
XOO_RS16820	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XOO_RS16825	COG3588	fructose-bisphosphate aldolase
XOO_RS16830	COG0469	pyruvate kinase activity
XOO_RS16870	COG0753	catalase activity
XOO_RS16890	COG1917	Cupin 2, conserved barrel domain protein
XOO_RS16890	COG2207	Transcriptional regulator
XOO_RS16915	COG0823	Involved in the tonB-independent uptake of proteins
XOO_RS16915	COG1506	peptidase
XOO_RS16930	COG1297	OPT oligopeptide transporter protein
XOO_RS17050	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
XOO_RS17055	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
XOO_RS17075	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
XOO_RS17220	COG3179	chitinase
XOO_RS17315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XOO_RS17420	COG2963	transposase activity
XOO_RS17450	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XOO_RS17465	COG2197	response regulator
XOO_RS17470	COG4585	Histidine kinase
XOO_RS17485	COG2894	cell division
XOO_RS17490	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XOO_RS17500	COG0642	Histidine kinase
XOO_RS17505	COG0745	RESPONSE REGULATOR receiver
XOO_RS17510	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
XOO_RS17520	COG2194	sulfuric ester hydrolase activity
XOO_RS17595	COG2963	transposase activity
XOO_RS17605	COG3293	Transposase
XOO_RS17630	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XOO_RS17635	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XOO_RS17645	COG0201	protein transport
XOO_RS17655	COG1841	ribosomal large subunit assembly
XOO_RS17685	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XOO_RS17695	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XOO_RS17700	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XOO_RS17705	COG0255	Belongs to the universal ribosomal protein uL29 family
XOO_RS17710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XOO_RS17735	COG0089	rRNA binding
XOO_RS17740	COG0088	Forms part of the polypeptide exit tunnel
XOO_RS17745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XOO_RS17750	COG0051	transcription antitermination factor activity, RNA binding
XOO_RS17770	COG0049	tRNA binding
XOO_RS17775	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XOO_RS17780	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XOO_RS17785	COG0085	RNA polymerase activity
XOO_RS17790	COG0222	ribosome binding
XOO_RS17795	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XOO_RS17805	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XOO_RS17810	COG0250	Participates in transcription elongation, termination and antitermination
XOO_RS17815	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XOO_RS17845	COG0012	GTP binding
XOO_RS17850	COG0193	aminoacyl-tRNA hydrolase activity
XOO_RS17860	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XOO_RS17875	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XOO_RS17885	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XOO_RS17890	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XOO_RS17900	COG0521	Mo-molybdopterin cofactor biosynthetic process
XOO_RS17920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XOO_RS17925	COG1295	ribonuclease BN
XOO_RS17950	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XOO_RS17955	COG1404	Belongs to the peptidase S8 family
XOO_RS17960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XOO_RS17990	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
XOO_RS18015	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XOO_RS18025	COG3039	Transposase
XOO_RS18040	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XOO_RS18040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XOO_RS18080	COG2890	protein-(glutamine-N5) methyltransferase activity
XOO_RS18090	COG3634	alkyl hydroperoxide reductase activity
XOO_RS18095	COG0583	DNA-binding transcription factor activity
XOO_RS18100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XOO_RS18125	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XOO_RS18160	COG4783	chaperone-mediated protein folding
XOO_RS18175	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XOO_RS18185	COG0438	transferase activity, transferring glycosyl groups
XOO_RS18190	COG0671	phosphoesterase, PA-phosphatase related
XOO_RS18195	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XOO_RS18205	COG2833	Protein of unknown function (DUF455)
XOO_RS18225	COG0285	dihydrofolate synthase activity
XOO_RS18230	COG0588	phosphoglycerate mutase activity
XOO_RS18260	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XOO_RS18265	COG4208	sulfate ABC transporter
XOO_RS18270	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XOO_RS18275	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XOO_RS18280	COG0156	8-amino-7-oxononanoate synthase activity
XOO_RS18305	COG0604	alcohol dehydrogenase
XOO_RS18310	COG1902	pentaerythritol trinitrate reductase activity
XOO_RS18310	COG0446	pyridine nucleotide-disulphide oxidoreductase
XOO_RS18320	COG2963	transposase activity
XOO_RS18385	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS18395	COG3293	Transposase
XOO_RS18455	COG1024	Enoyl-CoA hydratase
XOO_RS18465	COG0318	PFAM AMP-dependent synthetase and ligase
XOO_RS18470	COG0583	DNA-binding transcription factor activity
XOO_RS18510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XOO_RS18515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XOO_RS18525	COG2096	Adenosyltransferase
XOO_RS18530	COG0123	including yeast histone deacetylase and acetoin utilization protein
XOO_RS18545	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XOO_RS18550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XOO_RS18555	COG2967	ApaG domain
XOO_RS18580	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XOO_RS18600	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XOO_RS18620	COG0642	Histidine kinase
XOO_RS18635	COG4181	ATPase activity
XOO_RS18645	COG2175	clavaminate synthase activity
XOO_RS18690	COG3293	Transposase
XOO_RS18700	COG0667	Aldo Keto reductase
XOO_RS18715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XOO_RS18730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XOO_RS18735	COG4106	trans-aconitate 2-methyltransferase activity
XOO_RS18745	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XOO_RS18785	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XOO_RS18790	COG2226	methyltransferase
XOO_RS18840	COG0604	alcohol dehydrogenase
XOO_RS18840	COG3321	synthase
XOO_RS18840	COG1028	Short-chain dehydrogenase reductase Sdr
XOO_RS18850	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XOO_RS18865	COG0494	nUDIX hydrolase
XOO_RS18880	COG4942	peptidase
XOO_RS18880	COG1388	LysM domain
XOO_RS18890	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XOO_RS18905	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XOO_RS18910	COG1181	Belongs to the D-alanine--D-alanine ligase family
XOO_RS18915	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XOO_RS18935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XOO_RS18950	COG3116	cell division
XOO_RS18985	COG0792	nuclease activity
XOO_RS18990	COG1988	membrane-bound metal-dependent
XOO_RS18995	COG0277	FAD linked oxidase domain protein
XOO_RS19000	COG0745	RESPONSE REGULATOR receiver
XOO_RS19005	COG2205	protein histidine kinase activity
XOO_RS19015	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XOO_RS19020	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XOO_RS19045	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XOO_RS19050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XOO_RS19055	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XOO_RS19075	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XOO_RS19075	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XOO_RS19095	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XOO_RS19115	COG0488	(ABC) transporter
XOO_RS19140	COG3791	Glutathione-dependent formaldehyde-activating
XOO_RS19170	COG2205	protein histidine kinase activity
XOO_RS19220	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XOO_RS19245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XOO_RS19255	COG2963	transposase activity
XOO_RS19275	COG3039	Transposase
XOO_RS19315	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS19320	COG3039	Transposase
XOO_RS19345	COG1649	PFAM Uncharacterised BCR, COG1649
XOO_RS19345	COG0726	polysaccharide deacetylase
XOO_RS19350	COG1215	transferase activity, transferring glycosyl groups
XOO_RS19360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XOO_RS19365	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XOO_RS19370	COG1609	Transcriptional regulator
XOO_RS19380	COG2188	Transcriptional regulator
XOO_RS19395	COG3250	beta-galactosidase activity
XOO_RS19410	COG2963	transposase activity
XOO_RS19440	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XOO_RS19445	COG4191	Histidine kinase
XOO_RS19450	COG0784	Response regulator, receiver
XOO_RS19455	COG4251	negative regulation of phosphorylation
XOO_RS19460	COG2823	Periplasmic or secreted lipoprotein
XOO_RS19465	COG0673	inositol 2-dehydrogenase activity
XOO_RS19470	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XOO_RS19510	COG1051	belongs to the nudix hydrolase family
XOO_RS19510	COG1056	cytidyltransferase-related domain
XOO_RS19545	COG2921	Belongs to the UPF0250 family
XOO_RS19555	COG1686	Belongs to the peptidase S11 family
XOO_RS19560	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XOO_RS19565	COG2951	lytic endotransglycosylase activity
XOO_RS19615	COG0772	Belongs to the SEDS family
XOO_RS19630	COG1792	Involved in formation and maintenance of cell shape
XOO_RS19635	COG1077	Cell shape determining protein MreB Mrl
XOO_RS19640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XOO_RS19650	COG3039	Transposase
XOO_RS19705	COG2199	diguanylate cyclase activity
XOO_RS19710	COG0308	aminopeptidase N
XOO_RS19735	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XOO_RS19765	COG0436	Aminotransferase
XOO_RS19775	COG1505	serine-type exopeptidase activity
XOO_RS19810	COG3275	phosphorelay sensor kinase activity
XOO_RS19825	COG3293	Transposase
XOO_RS19850	COG0659	secondary active sulfate transmembrane transporter activity
XOO_RS19855	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XOO_RS19855	COG5297	Belongs to the glycosyl hydrolase family 6
XOO_RS19865	COG0840	transmembrane signaling receptor activity
XOO_RS19895	COG3293	Transposase
XOO_RS19935	COG0598	Magnesium transport protein CorA
XOO_RS19945	COG1113	amino acid transport
XOO_RS19950	COG5297	Belongs to the glycosyl hydrolase family 6
XOO_RS19955	COG4305	rare lipoprotein A
XOO_RS19960	COG0697	spore germination
XOO_RS20020	COG4221	oxidoreductase activity
XOO_RS20035	COG2963	transposase activity
XOO_RS20055	COG0456	acetyltransferase
XOO_RS20065	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XOO_RS20115	COG2111	Na H antiporter
XOO_RS20115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XOO_RS20120	COG1006	Multisubunit Na H antiporter MnhC subunit
XOO_RS20125	COG0651	ATP synthesis coupled electron transport
XOO_RS20135	COG2212	antiporter activity
XOO_RS20140	COG1320	monovalent cation:proton antiporter activity
XOO_RS20165	COG3104	oligopeptide transport
XOO_RS20170	COG3483	tryptophan 2,3-dioxygenase activity
XOO_RS20180	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XOO_RS20195	COG0022	dehydrogenase e1 component
XOO_RS20210	COG0183	Belongs to the thiolase family
XOO_RS20280	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XOO_RS20285	COG3023	N-Acetylmuramoyl-L-alanine amidase
XOO_RS20295	COG4948	Mandelate Racemase Muconate Lactonizing
XOO_RS20315	COG3293	Transposase
XOO_RS20325	COG0531	amino acid
XOO_RS20335	COG3293	Transposase
XOO_RS20350	COG4682	membrane
XOO_RS20355	COG2133	pyrroloquinoline quinone binding
XOO_RS20380	COG3293	Transposase
XOO_RS20395	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS20405	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XOO_RS20410	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XOO_RS20420	COG1610	YqeY-like protein
XOO_RS20425	COG1295	ribonuclease BN
XOO_RS20430	COG0358	DNA primase activity
XOO_RS20490	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XOO_RS20505	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XOO_RS20515	COG3293	Transposase
XOO_RS20530	COG2963	transposase activity
XOO_RS20535	COG2801	Transposase and inactivated derivatives
XOO_RS20570	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XOO_RS20575	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XOO_RS20580	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XOO_RS20590	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XOO_RS20595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XOO_RS20610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XOO_RS20635	COG2963	transposase activity
XOO_RS20640	COG2801	Transposase and inactivated derivatives
XOO_RS20700	COG3039	Transposase
XOO_RS20715	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XOO_RS20715	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XOO_RS20725	COG1473	amidohydrolase
XOO_RS20730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XOO_RS20735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XOO_RS20745	COG5383	Protein conserved in bacteria
XOO_RS20770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XOO_RS20775	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XOO_RS20790	COG0028	Belongs to the TPP enzyme family
XOO_RS20795	COG4191	Histidine kinase
XOO_RS20820	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XOO_RS20835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XOO_RS20840	COG3177	Filamentation induced by cAMP protein fic
XOO_RS20855	COG0596	Alpha beta hydrolase
XOO_RS20860	COG0727	PFAM Uncharacterised protein family (UPF0153)
XOO_RS20865	COG0318	PFAM AMP-dependent synthetase and ligase
XOO_RS20870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XOO_RS20925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XOO_RS20935	COG0129	dihydroxy-acid dehydratase activity
XOO_RS20955	COG3039	Transposase
XOO_RS20965	COG0408	coproporphyrinogen oxidase activity
XOO_RS21000	COG0232	Belongs to the dGTPase family. Type 2 subfamily
XOO_RS21030	COG3039	Transposase
XOO_RS21090	COG2353	YceI-like domain
XOO_RS21125	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XOO_RS21140	COG3386	PFAM SMP-30 Gluconolaconase
XOO_RS21185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XOO_RS21195	COG4771	TonB-dependent receptor
XOO_RS21205	COG0459	protein refolding
XOO_RS21240	COG1252	NADH dehydrogenase
XOO_RS21250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XOO_RS21255	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XOO_RS21260	COG2201	protein-glutamate methylesterase activity
XOO_RS21265	COG2177	Part of the ABC transporter FtsEX involved in
XOO_RS21270	COG2884	Cell division ATP-binding protein ftsE
XOO_RS21280	COG3118	belongs to the thioredoxin family
XOO_RS21285	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XOO_RS21290	COG2801	Transposase and inactivated derivatives
XOO_RS21295	COG2963	transposase activity
XOO_RS21305	COG0729	surface antigen
XOO_RS21340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XOO_RS21355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XOO_RS21410	COG1733	regulation of RNA biosynthetic process
XOO_RS21415	COG0702	epimerase
XOO_RS21450	COG0583	DNA-binding transcription factor activity
XOO_RS21455	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XOO_RS21465	COG2205	protein histidine kinase activity
XOO_RS21470	COG2205	protein histidine kinase activity
XOO_RS21475	COG0745	RESPONSE REGULATOR receiver
XOO_RS21495	COG1902	pentaerythritol trinitrate reductase activity
XOO_RS21500	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XOO_RS21510	COG2814	Major facilitator Superfamily
XOO_RS21515	COG0583	DNA-binding transcription factor activity
XOO_RS21525	COG0084	hydrolase, TatD family'
XOO_RS21565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XOO_RS21585	COG2351	hydroxyisourate hydrolase activity
XOO_RS21620	COG2826	transposase and inactivated derivatives, IS30 family
XOO_RS21630	COG4770	biotin carboxylase activity
XOO_RS21635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XOO_RS21640	COG1960	acyl-CoA dehydrogenase activity
XOO_RS21700	COG0523	cobalamin synthesis protein
XOO_RS21710	COG0697	spore germination
XOO_RS21720	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XOO_RS21735	COG4771	TonB-dependent receptor
XOO_RS21740	COG0457	Tetratricopeptide repeat
XOO_RS21750	COG0752	glycyl-tRNA synthetase alpha subunit
XOO_RS21755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XOO_RS21770	COG0519	Catalyzes the synthesis of GMP from XMP
XOO_RS21770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XOO_RS21780	COG0805	protein transport
XOO_RS21790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XOO_RS21800	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XOO_RS21820	COG2974	May be involved in recombination
XOO_RS21840	COG3661	Belongs to the glycosyl hydrolase 67 family
XOO_RS21850	COG4948	Mandelate Racemase Muconate Lactonizing
XOO_RS21860	COG1472	Belongs to the glycosyl hydrolase 3 family
XOO_RS21865	COG0246	Mannitol dehydrogenase
XOO_RS21890	COG3693	PFAM glycoside hydrolase, family 10
XOO_RS21895	COG3693	PFAM glycoside hydrolase, family 10
XOO_RS21915	COG2211	Major facilitator Superfamily
XOO_RS21950	COG3293	Transposase
XOO_RS21960	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XOO_RS22005	COG1846	Transcriptional regulator
XOO_RS22010	COG1764	response to oxidative stress
XOO_RS22085	COG3549	Plasmid maintenance system killer
XOO_RS22090	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XOO_RS22095	COG1074	ATP-dependent DNA helicase activity
XOO_RS22100	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XOO_RS22105	COG1196	nuclear chromosome segregation
XOO_RS22140	COG2032	superoxide dismutase activity
XOO_RS22145	COG2032	superoxide dismutase activity
XOO_RS22150	COG2204	response regulator
XOO_RS22155	COG3852	Histidine kinase
XOO_RS22160	COG0004	ammonium transporteR
XOO_RS22165	COG0347	Belongs to the P(II) protein family
XOO_RS22170	COG0174	glutamine synthetase
XOO_RS22175	COG1968	undecaprenyl-diphosphatase activity
XOO_RS22220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XOO_RS22230	COG2062	phosphohistidine phosphatase, SixA
XOO_RS22235	COG0489	protein tyrosine kinase activity
XOO_RS22260	COG1396	sequence-specific DNA binding
XOO_RS22265	COG3550	peptidyl-serine autophosphorylation
XOO_RS22270	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XOO_RS22275	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XOO_RS22290	COG0517	IMP dehydrogenase activity
XOO_RS22290	COG1125	glycine betaine transport
XOO_RS22305	COG1119	ATPase activity
XOO_RS22315	COG1752	Esterase of the alpha-beta hydrolase superfamily
XOO_RS22335	COG2963	transposase activity
XOO_RS22350	COG0656	L-ascorbic acid biosynthetic process
XOO_RS22355	COG2130	NADP-dependent
XOO_RS22360	COG0667	Aldo Keto reductase
XOO_RS22370	COG1187	pseudouridine synthase activity
XOO_RS22385	COG1643	Atp-dependent helicase
XOO_RS22390	COG4807	Protein conserved in bacteria
XOO_RS22395	COG4948	Mandelate Racemase Muconate Lactonizing
XOO_RS22400	COG0179	Fumarylacetoacetate (FAA) hydrolase
XOO_RS22405	COG1028	Short-chain dehydrogenase reductase Sdr
XOO_RS22425	COG3507	Belongs to the glycosyl hydrolase 43 family
XOO_RS22465	COG3162	membrane
XOO_RS22470	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XOO_RS22480	COG0708	Exodeoxyribonuclease III
XOO_RS22495	COG2091	lysine biosynthetic process via aminoadipic acid
XOO_RS22505	COG3540	Alkaline phosphatase
XOO_RS22510	COG0357	Ribosomal RNA small subunit methyltransferase G
XOO_RS22535	COG2159	amidohydrolase
XOO_RS22545	COG2159	amidohydrolase
XOO_RS22555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XOO_RS22560	COG0583	DNA-binding transcription factor activity
XOO_RS22565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XOO_RS22580	COG0210	DNA helicase
XOO_RS22595	COG0531	amino acid
XOO_RS22600	COG1322	Protein conserved in bacteria
XOO_RS22610	COG0386	Belongs to the glutathione peroxidase family
XOO_RS22625	COG3293	Transposase
XOO_RS22660	COG0793	Belongs to the peptidase S41A family
XOO_RS22665	COG4942	peptidase
XOO_RS22675	COG2234	aminopeptidase activity
XOO_RS22725	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XOO_RS22730	COG0302	gtp cyclohydrolase
XOO_RS22750	COG0477	Major facilitator Superfamily
XOO_RS22830	COG1929	Belongs to the glycerate kinase type-1 family
XOO_RS22835	COG2271	Major facilitator Superfamily
XOO_RS22850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XOO_RS22855	COG0861	Integral membrane protein TerC family
XOO_RS22865	COG0584	glycerophosphoryl diester phosphodiesterase
XOO_RS22875	COG0671	phosphoesterase, PA-phosphatase related
XOO_RS22885	COG0726	polysaccharide deacetylase
XOO_RS22910	COG1116	anion transmembrane transporter activity
XOO_RS22970	COG0732	type I restriction modification DNA specificity domain