locus-tag	class	description
BVV16_RS00020	COG0187	DNA topoisomerase II activity
BVV16_RS00030	COG0501	Belongs to the peptidase M48B family
BVV16_RS00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BVV16_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVV16_RS00090	COG3039	Transposase
BVV16_RS00140	COG0793	Belongs to the peptidase S41A family
BVV16_RS00145	COG4942	peptidase
BVV16_RS00155	COG2234	aminopeptidase activity
BVV16_RS00165	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BVV16_RS00180	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BVV16_RS00190	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BVV16_RS00200	COG1064	alcohol dehydrogenase
BVV16_RS00230	COG0493	'glutamate synthase
BVV16_RS00235	COG0067	glutamate synthase
BVV16_RS00235	COG0069	glutamate synthase activity
BVV16_RS00235	COG0070	glutamate synthase
BVV16_RS00305	COG1111	helicase
BVV16_RS00305	COG1205	dead DEAH box helicase
BVV16_RS00310	COG1272	protein, Hemolysin III
BVV16_RS00340	COG2032	superoxide dismutase activity
BVV16_RS00345	COG2204	response regulator
BVV16_RS00350	COG3852	Histidine kinase
BVV16_RS00355	COG0004	ammonium transporteR
BVV16_RS00360	COG0347	Belongs to the P(II) protein family
BVV16_RS00365	COG0174	glutamine synthetase
BVV16_RS00370	COG1968	undecaprenyl-diphosphatase activity
BVV16_RS00420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVV16_RS00430	COG2062	phosphohistidine phosphatase, SixA
BVV16_RS00435	COG0489	protein tyrosine kinase activity
BVV16_RS00455	COG1396	sequence-specific DNA binding
BVV16_RS00460	COG3550	peptidyl-serine autophosphorylation
BVV16_RS00465	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BVV16_RS00470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BVV16_RS00485	COG1125	glycine betaine transport
BVV16_RS00500	COG1119	ATPase activity
BVV16_RS00515	COG1752	Esterase of the alpha-beta hydrolase superfamily
BVV16_RS00525	COG1522	sequence-specific DNA binding
BVV16_RS00530	COG3186	Phenylalanine-4-hydroxylase
BVV16_RS00560	COG1609	Transcriptional regulator
BVV16_RS00605	COG0366	Alpha amylase catalytic
BVV16_RS00610	COG0366	Alpha amylase catalytic
BVV16_RS00620	COG3039	Transposase
BVV16_RS00670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVV16_RS00675	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BVV16_RS00690	COG0028	Belongs to the TPP enzyme family
BVV16_RS00695	COG4191	Histidine kinase
BVV16_RS00720	COG3039	Transposase
BVV16_RS00730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BVV16_RS00745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVV16_RS00750	COG3177	Filamentation induced by cAMP protein fic
BVV16_RS00755	COG0596	Alpha beta hydrolase
BVV16_RS00765	COG0727	PFAM Uncharacterised protein family (UPF0153)
BVV16_RS00770	COG0318	PFAM AMP-dependent synthetase and ligase
BVV16_RS00775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVV16_RS00790	COG1181	Belongs to the D-alanine--D-alanine ligase family
BVV16_RS00805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BVV16_RS00820	COG0564	pseudouridine synthase activity
BVV16_RS00850	COG0339	signal peptide processing
BVV16_RS00895	COG4770	biotin carboxylase activity
BVV16_RS00905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BVV16_RS00910	COG1960	acyl-CoA dehydrogenase activity
BVV16_RS00955	COG0523	cobalamin synthesis protein
BVV16_RS00965	COG0697	spore germination
BVV16_RS00975	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BVV16_RS00980	COG1846	Transcriptional regulator
BVV16_RS00985	COG1764	response to oxidative stress
BVV16_RS01035	COG0656	L-ascorbic acid biosynthetic process
BVV16_RS01050	COG2130	NADP-dependent
BVV16_RS01065	COG1187	pseudouridine synthase activity
BVV16_RS01080	COG1643	Atp-dependent helicase
BVV16_RS01090	COG4807	Protein conserved in bacteria
BVV16_RS01095	COG2072	flavoprotein involved in K transport
BVV16_RS01115	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BVV16_RS01120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVV16_RS01160	COG3039	Transposase
BVV16_RS01205	COG0084	hydrolase, TatD family'
BVV16_RS01225	COG0583	DNA-binding transcription factor activity
BVV16_RS01230	COG2814	Major facilitator Superfamily
BVV16_RS01240	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BVV16_RS01245	COG1902	pentaerythritol trinitrate reductase activity
BVV16_RS01275	COG0745	RESPONSE REGULATOR receiver
BVV16_RS01295	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BVV16_RS01300	COG0583	DNA-binding transcription factor activity
BVV16_RS01330	COG0702	epimerase
BVV16_RS01335	COG1733	regulation of RNA biosynthetic process
BVV16_RS01370	COG3039	Transposase
BVV16_RS01405	COG0129	dihydroxy-acid dehydratase activity
BVV16_RS01415	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BVV16_RS01485	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BVV16_RS01500	COG3485	protocatechuate 3,4-dioxygenase
BVV16_RS01505	COG3485	protocatechuate 3,4-dioxygenase
BVV16_RS01520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVV16_RS01525	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVV16_RS01540	COG1414	Transcriptional regulator
BVV16_RS01580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BVV16_RS01620	COG0156	8-amino-7-oxononanoate synthase activity
BVV16_RS01625	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BVV16_RS01630	COG1040	competence protein
BVV16_RS01635	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BVV16_RS01745	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BVV16_RS01820	COG3264	Mechanosensitive ion channel
BVV16_RS01820	COG1511	domain protein
BVV16_RS01830	COG3039	Transposase
BVV16_RS01835	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BVV16_RS01845	COG2354	Protein conserved in bacteria
BVV16_RS01875	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BVV16_RS01900	COG0702	epimerase
BVV16_RS01910	COG1028	Short-chain dehydrogenase reductase Sdr
BVV16_RS01955	COG0513	Belongs to the DEAD box helicase family
BVV16_RS01965	COG3039	Transposase
BVV16_RS01995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BVV16_RS02005	COG3483	tryptophan 2,3-dioxygenase activity
BVV16_RS02010	COG3104	oligopeptide transport
BVV16_RS02030	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BVV16_RS02040	COG1320	monovalent cation:proton antiporter activity
BVV16_RS02045	COG2212	antiporter activity
BVV16_RS02055	COG0651	ATP synthesis coupled electron transport
BVV16_RS02060	COG1006	Multisubunit Na H antiporter MnhC subunit
BVV16_RS02065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BVV16_RS02065	COG2111	Na H antiporter
BVV16_RS02100	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BVV16_RS02110	COG0456	acetyltransferase
BVV16_RS02150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BVV16_RS02155	COG0134	indole-3-glycerol-phosphate synthase activity
BVV16_RS02165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVV16_RS02170	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BVV16_RS02180	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BVV16_RS02185	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BVV16_RS02190	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BVV16_RS02260	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BVV16_RS02280	COG2814	Major facilitator Superfamily
BVV16_RS02290	COG2814	Major facilitator Superfamily
BVV16_RS02295	COG1289	transmembrane transporter activity
BVV16_RS02305	COG0151	Belongs to the GarS family
BVV16_RS02315	COG0419	ATPase involved in DNA repair
BVV16_RS02320	COG0138	bifunctional purine biosynthesis protein purh
BVV16_RS02325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BVV16_RS02335	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BVV16_RS02390	COG0439	Biotin carboxylase
BVV16_RS02400	COG0511	ligase activity, forming carbon-carbon bonds
BVV16_RS02405	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BVV16_RS02420	COG1324	tolerance protein
BVV16_RS02440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BVV16_RS02460	COG0534	Mate efflux family protein
BVV16_RS02465	COG0616	signal peptide processing
BVV16_RS02475	COG1028	Short-chain dehydrogenase reductase Sdr
BVV16_RS02490	COG0009	L-threonylcarbamoyladenylate synthase
BVV16_RS02495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BVV16_RS02495	COG1754	DNA topoisomerase type I activity
BVV16_RS02515	COG0758	DNA mediated transformation
BVV16_RS02520	COG1652	LysM domain
BVV16_RS02525	COG0242	peptide deformylase activity
BVV16_RS02530	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BVV16_RS02535	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BVV16_RS02535	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BVV16_RS02585	COG1560	Kdo2-lipid A biosynthetic process
BVV16_RS02595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BVV16_RS02765	COG3179	chitinase
BVV16_RS02810	COG4695	Portal protein
BVV16_RS02885	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BVV16_RS02890	COG3118	belongs to the thioredoxin family
BVV16_RS02900	COG2884	Cell division ATP-binding protein ftsE
BVV16_RS02905	COG2177	Part of the ABC transporter FtsEX involved in
BVV16_RS02910	COG3437	response regulator, receiver
BVV16_RS02915	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BVV16_RS02920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BVV16_RS02925	COG2860	membrane
BVV16_RS02930	COG1252	NADH dehydrogenase
BVV16_RS02955	COG0459	protein refolding
BVV16_RS02970	COG3039	Transposase
BVV16_RS02980	COG3039	Transposase
BVV16_RS02990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BVV16_RS03005	COG3386	PFAM SMP-30 Gluconolaconase
BVV16_RS03020	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BVV16_RS03075	COG2353	YceI-like domain
BVV16_RS03170	COG4221	oxidoreductase activity
BVV16_RS03225	COG0697	spore germination
BVV16_RS03230	COG4305	rare lipoprotein A
BVV16_RS03235	COG5297	Belongs to the glycosyl hydrolase family 6
BVV16_RS03245	COG1113	amino acid transport
BVV16_RS03255	COG0598	Magnesium transport protein CorA
BVV16_RS03330	COG5001	Diguanylate cyclase
BVV16_RS03330	COG3300	MHYT domain
BVV16_RS03355	COG5297	Belongs to the glycosyl hydrolase family 6
BVV16_RS03355	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BVV16_RS03360	COG0659	secondary active sulfate transmembrane transporter activity
BVV16_RS03395	COG3275	phosphorelay sensor kinase activity
BVV16_RS03405	COG0181	hydroxymethylbilane synthase activity
BVV16_RS03430	COG1505	serine-type exopeptidase activity
BVV16_RS03440	COG0436	Aminotransferase
BVV16_RS03450	COG2832	Protein of unknown function (DUF454)
BVV16_RS03470	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BVV16_RS03480	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BVV16_RS03515	COG5001	Diguanylate cyclase
BVV16_RS03515	COG3300	MHYT domain
BVV16_RS03520	COG0308	aminopeptidase N
BVV16_RS03535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVV16_RS03540	COG1077	Cell shape determining protein MreB Mrl
BVV16_RS03545	COG1792	Involved in formation and maintenance of cell shape
BVV16_RS03560	COG0772	Belongs to the SEDS family
BVV16_RS03585	COG2951	lytic endotransglycosylase activity
BVV16_RS03590	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BVV16_RS03595	COG1686	Belongs to the peptidase S11 family
BVV16_RS03610	COG2921	Belongs to the UPF0250 family
BVV16_RS03635	COG1056	cytidyltransferase-related domain
BVV16_RS03635	COG1051	belongs to the nudix hydrolase family
BVV16_RS03670	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BVV16_RS03675	COG0673	inositol 2-dehydrogenase activity
BVV16_RS03680	COG2823	Periplasmic or secreted lipoprotein
BVV16_RS03685	COG4251	negative regulation of phosphorylation
BVV16_RS03690	COG0784	Response regulator, receiver
BVV16_RS03695	COG4191	Histidine kinase
BVV16_RS03700	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BVV16_RS03725	COG3039	Transposase
BVV16_RS03740	COG3250	beta-galactosidase activity
BVV16_RS03755	COG2188	Transcriptional regulator
BVV16_RS03765	COG1609	Transcriptional regulator
BVV16_RS03770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BVV16_RS03775	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BVV16_RS03790	COG1215	transferase activity, transferring glycosyl groups
BVV16_RS03795	COG0726	polysaccharide deacetylase
BVV16_RS03795	COG1649	PFAM Uncharacterised BCR, COG1649
BVV16_RS03815	COG3039	Transposase
BVV16_RS03855	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BVV16_RS03905	COG2205	protein histidine kinase activity
BVV16_RS03935	COG3791	Glutathione-dependent formaldehyde-activating
BVV16_RS03950	COG3039	Transposase
BVV16_RS03965	COG0488	(ABC) transporter
BVV16_RS03985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BVV16_RS03995	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BVV16_RS04005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVV16_RS04005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVV16_RS04025	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BVV16_RS04030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BVV16_RS04035	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BVV16_RS04060	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BVV16_RS04065	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BVV16_RS04075	COG2205	protein histidine kinase activity
BVV16_RS04080	COG0745	RESPONSE REGULATOR receiver
BVV16_RS04110	COG0277	FAD linked oxidase domain protein
BVV16_RS04120	COG0792	nuclease activity
BVV16_RS04160	COG0275	rRNA processing
BVV16_RS04165	COG3116	cell division
BVV16_RS04180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BVV16_RS04185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVV16_RS04200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BVV16_RS04205	COG1181	Belongs to the D-alanine--D-alanine ligase family
BVV16_RS04210	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BVV16_RS04225	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BVV16_RS04235	COG0741	lytic transglycosylase activity
BVV16_RS04235	COG0739	heme binding
BVV16_RS04235	COG1196	nuclear chromosome segregation
BVV16_RS04250	COG0494	nUDIX hydrolase
BVV16_RS04265	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BVV16_RS04280	COG3321	synthase
BVV16_RS04280	COG1028	Short-chain dehydrogenase reductase Sdr
BVV16_RS04280	COG0604	alcohol dehydrogenase
BVV16_RS04340	COG2226	methyltransferase
BVV16_RS04345	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BVV16_RS04385	COG2826	transposase and inactivated derivatives, IS30 family
BVV16_RS04410	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BVV16_RS04425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVV16_RS04435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVV16_RS04440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BVV16_RS04450	COG0667	Aldo Keto reductase
BVV16_RS04480	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BVV16_RS04490	COG2175	clavaminate synthase activity
BVV16_RS04500	COG4181	ATPase activity
BVV16_RS04515	COG0642	Histidine kinase
BVV16_RS04530	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BVV16_RS04550	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BVV16_RS04570	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BVV16_RS04575	COG2967	ApaG domain
BVV16_RS04580	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BVV16_RS04595	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BVV16_RS04610	COG0123	including yeast histone deacetylase and acetoin utilization protein
BVV16_RS04615	COG2096	Adenosyltransferase
BVV16_RS04630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVV16_RS04635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVV16_RS04655	COG1802	Transcriptional regulator
BVV16_RS04665	COG3384	dioxygenase
BVV16_RS04670	COG0583	DNA-binding transcription factor activity
BVV16_RS04675	COG0318	PFAM AMP-dependent synthetase and ligase
BVV16_RS04685	COG1024	Enoyl-CoA hydratase
BVV16_RS04705	COG3386	PFAM SMP-30 Gluconolaconase
BVV16_RS04755	COG2197	response regulator
BVV16_RS04765	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVV16_RS04770	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BVV16_RS04775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BVV16_RS04785	COG0583	DNA-binding transcription factor activity
BVV16_RS04790	COG3634	alkyl hydroperoxide reductase activity
BVV16_RS04800	COG2890	protein-(glutamine-N5) methyltransferase activity
BVV16_RS04840	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVV16_RS04840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVV16_RS04910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVV16_RS04920	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BVV16_RS04950	COG1295	ribonuclease BN
BVV16_RS04955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVV16_RS04960	COG1254	Belongs to the acylphosphatase family
BVV16_RS04975	COG0521	Mo-molybdopterin cofactor biosynthetic process
BVV16_RS04985	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BVV16_RS04990	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BVV16_RS05000	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BVV16_RS05015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BVV16_RS05025	COG0193	aminoacyl-tRNA hydrolase activity
BVV16_RS05030	COG0012	GTP binding
BVV16_RS05065	COG0250	Participates in transcription elongation, termination and antitermination
BVV16_RS05075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BVV16_RS05080	COG0081	regulation of translation
BVV16_RS05085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BVV16_RS05095	COG0085	RNA polymerase activity
BVV16_RS05100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BVV16_RS05105	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BVV16_RS05110	COG0049	tRNA binding
BVV16_RS05140	COG0088	Forms part of the polypeptide exit tunnel
BVV16_RS05145	COG0089	rRNA binding
BVV16_RS05150	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BVV16_RS05160	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BVV16_RS05170	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BVV16_RS05175	COG0255	Belongs to the universal ribosomal protein uL29 family
BVV16_RS05180	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BVV16_RS05185	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BVV16_RS05190	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BVV16_RS05225	COG1841	ribosomal large subunit assembly
BVV16_RS05230	COG0200	Binds to the 23S rRNA
BVV16_RS05235	COG0201	protein transport
BVV16_RS05245	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BVV16_RS05250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BVV16_RS05260	COG0203	ribosomal protein L17
BVV16_RS05275	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BVV16_RS05295	COG1217	gtp-binding protein TYPA
BVV16_RS05300	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BVV16_RS05310	COG0625	glutathione transferase activity
BVV16_RS05340	COG3039	Transposase
BVV16_RS05360	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVV16_RS05360	COG1902	pentaerythritol trinitrate reductase activity
BVV16_RS05365	COG0604	alcohol dehydrogenase
BVV16_RS05395	COG0156	8-amino-7-oxononanoate synthase activity
BVV16_RS05400	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BVV16_RS05405	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BVV16_RS05410	COG4208	sulfate ABC transporter
BVV16_RS05415	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BVV16_RS05450	COG0406	alpha-ribazole phosphatase activity
BVV16_RS05460	COG0285	dihydrofolate synthase activity
BVV16_RS05480	COG2833	Protein of unknown function (DUF455)
BVV16_RS05505	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVV16_RS05515	COG0671	phosphoesterase, PA-phosphatase related
BVV16_RS05520	COG0438	transferase activity, transferring glycosyl groups
BVV16_RS05530	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BVV16_RS05535	COG5002	protein histidine kinase activity
BVV16_RS05545	COG4783	chaperone-mediated protein folding
BVV16_RS05560	COG0473	3-isopropylmalate dehydrogenase activity
BVV16_RS05605	COG3039	Transposase
BVV16_RS05630	COG0544	peptidyl-prolyl cis-trans isomerase activity
BVV16_RS05670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVV16_RS05695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BVV16_RS05710	COG0631	protein serine/threonine phosphatase activity
BVV16_RS05730	COG3039	Transposase
BVV16_RS05740	COG0859	PFAM glycosyl transferase family 9
BVV16_RS05745	COG3642	lipopolysaccharide core region biosynthetic process
BVV16_RS05750	COG1234	tRNA 3'-trailer cleavage
BVV16_RS05755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BVV16_RS05765	COG0315	cyclic pyranopterin monophosphate synthase activity
BVV16_RS05770	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BVV16_RS05775	COG0314	molybdopterin synthase activity
BVV16_RS05810	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BVV16_RS05820	COG0537	adenosine 5'-monophosphoramidase activity
BVV16_RS05840	COG0714	Associated with various cellular activities
BVV16_RS05860	COG1399	metal-binding, possibly nucleic acid-binding protein
BVV16_RS05885	COG1028	Short-chain dehydrogenase reductase Sdr
BVV16_RS05890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVV16_RS05900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BVV16_RS05905	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BVV16_RS05935	COG3829	transcription factor binding
BVV16_RS06035	COG0330	HflC and HflK could
BVV16_RS06040	COG0330	HflC and HflK could
BVV16_RS06050	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BVV16_RS06055	COG0308	aminopeptidase N
BVV16_RS06090	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BVV16_RS06175	COG0587	DNA-directed DNA polymerase activity
BVV16_RS06195	COG1297	OPT oligopeptide transporter protein
BVV16_RS06210	COG0823	Involved in the tonB-independent uptake of proteins
BVV16_RS06210	COG1506	peptidase
BVV16_RS06220	COG1917	Cupin 2, conserved barrel domain protein
BVV16_RS06220	COG2207	Transcriptional regulator
BVV16_RS06265	COG0753	catalase activity
BVV16_RS06305	COG3551	Protein conserved in bacteria
BVV16_RS06335	COG2194	sulfuric ester hydrolase activity
BVV16_RS06345	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BVV16_RS06350	COG0745	RESPONSE REGULATOR receiver
BVV16_RS06355	COG0642	Histidine kinase
BVV16_RS06365	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BVV16_RS06370	COG2894	cell division
BVV16_RS06385	COG4585	Histidine kinase
BVV16_RS06390	COG2197	response regulator
BVV16_RS06405	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BVV16_RS06430	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BVV16_RS06505	COG2826	transposase and inactivated derivatives, IS30 family
BVV16_RS06530	COG3039	Transposase
BVV16_RS06665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BVV16_RS06680	COG1842	Phage shock protein A
BVV16_RS06705	COG0754	glutathionylspermidine amidase activity
BVV16_RS06785	COG0531	amino acid
BVV16_RS06790	COG2197	response regulator
BVV16_RS06795	COG2267	carboxylic ester hydrolase activity
BVV16_RS06805	COG1113	amino acid transport
BVV16_RS06835	COG3039	Transposase
BVV16_RS06845	COG1294	oxidase, subunit
BVV16_RS06855	COG2239	Acts as a magnesium transporter
BVV16_RS06865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BVV16_RS06870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVV16_RS06885	COG3039	Transposase
BVV16_RS06900	COG1660	Displays ATPase and GTPase activities
BVV16_RS06910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVV16_RS06925	COG1137	ATPase activity
BVV16_RS06930	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BVV16_RS06940	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BVV16_RS06950	COG0271	Belongs to the BolA IbaG family
BVV16_RS06955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BVV16_RS06980	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BVV16_RS06995	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BVV16_RS07005	COG0628	permease
BVV16_RS07015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BVV16_RS07020	COG3178	'Phosphotransferase
BVV16_RS07030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVV16_RS07035	COG1555	photosystem II stabilization
BVV16_RS07060	COG3039	Transposase
BVV16_RS07070	COG2146	nitrite reductase [NAD(P)H] activity
BVV16_RS07080	COG3039	Transposase
BVV16_RS07085	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BVV16_RS07090	COG0719	Fe-S assembly protein
BVV16_RS07095	COG0396	ATPase activity
BVV16_RS07100	COG0719	Fe-S assembly protein
BVV16_RS07105	COG1959	2 iron, 2 sulfur cluster binding
BVV16_RS07160	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BVV16_RS07195	COG0519	Catalyzes the synthesis of GMP from XMP
BVV16_RS07210	COG1678	Uncharacterized ACR, COG1678
BVV16_RS07215	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BVV16_RS07230	COG1764	response to oxidative stress
BVV16_RS07240	COG0384	phenazine biosynthesis protein PhzF
BVV16_RS07250	COG0527	aspartate kinase activity
BVV16_RS07280	COG3039	Transposase
BVV16_RS07290	COG0142	geranyltranstransferase activity
BVV16_RS07295	COG0629	single-stranded DNA binding
BVV16_RS07300	COG3706	GGDEF domain
BVV16_RS07300	COG2203	Gaf domain
BVV16_RS07300	COG5001	Diguanylate cyclase
BVV16_RS07300	COG4251	negative regulation of phosphorylation
BVV16_RS07345	COG2879	small protein
BVV16_RS07350	COG1966	Carbon starvation protein
BVV16_RS07355	COG1741	Belongs to the pirin family
BVV16_RS07460	COG1515	deoxyribonuclease V activity
BVV16_RS07480	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BVV16_RS07485	COG2202	Pas domain
BVV16_RS07485	COG2200	EAL domain
BVV16_RS07485	COG2199	diguanylate cyclase activity
BVV16_RS07490	COG0835	chemotaxis
BVV16_RS07495	COG0840	transmembrane signaling receptor activity
BVV16_RS07505	COG2198	Histidine kinase
BVV16_RS07505	COG0643	Histidine kinase
BVV16_RS07515	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BVV16_RS07525	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BVV16_RS07560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVV16_RS07565	COG0735	belongs to the Fur family
BVV16_RS07595	COG2826	transposase and inactivated derivatives, IS30 family
BVV16_RS07740	COG5002	protein histidine kinase activity
BVV16_RS07740	COG5001	Diguanylate cyclase
BVV16_RS07745	COG1187	pseudouridine synthase activity
BVV16_RS07765	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BVV16_RS07775	COG0475	glutathione-regulated potassium exporter activity
BVV16_RS07780	COG5000	phosphorelay sensor kinase activity
BVV16_RS07780	COG5002	protein histidine kinase activity
BVV16_RS07785	COG0745	RESPONSE REGULATOR receiver
BVV16_RS07790	COG1538	Outer membrane efflux protein
BVV16_RS07815	COG1132	(ABC) transporter
BVV16_RS07840	COG3039	Transposase
BVV16_RS07885	COG3118	belongs to the thioredoxin family
BVV16_RS07915	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BVV16_RS07935	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BVV16_RS07960	COG2968	Membrane
BVV16_RS07975	COG3164	Protein of unknown function
BVV16_RS07985	COG0312	modulator of DNA gyrase
BVV16_RS07990	COG3028	Belongs to the UPF0307 family
BVV16_RS07995	COG0312	modulator of DNA gyrase
BVV16_RS08010	COG4104	PAAR repeat-containing protein
BVV16_RS08020	COG0142	geranyltranstransferase activity
BVV16_RS08025	COG1722	exodeoxyribonuclease VII activity
BVV16_RS08030	COG0037	tRNA processing
BVV16_RS08035	COG1785	Belongs to the alkaline phosphatase family
BVV16_RS08040	COG1301	dicarboxylic acid transport
BVV16_RS08045	COG4106	trans-aconitate 2-methyltransferase activity
BVV16_RS08055	COG0791	NLP P60 protein
BVV16_RS08060	COG0791	NLP P60 protein
BVV16_RS08065	COG1047	Peptidyl-prolyl cis-trans
BVV16_RS08070	COG2311	Membrane
BVV16_RS08075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVV16_RS08105	COG3039	Transposase
BVV16_RS08115	COG2826	transposase and inactivated derivatives, IS30 family
BVV16_RS08135	COG2826	transposase and inactivated derivatives, IS30 family
BVV16_RS08140	COG3039	Transposase
BVV16_RS08155	COG0489	protein tyrosine kinase activity
BVV16_RS08165	COG0717	Belongs to the dCTP deaminase family
BVV16_RS08180	COG3039	Transposase
BVV16_RS08200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BVV16_RS08210	COG3039	Transposase
BVV16_RS08220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BVV16_RS08240	COG0433	COG0433 Predicted ATPase
BVV16_RS08270	COG2890	protein-(glutamine-N5) methyltransferase activity
BVV16_RS08275	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BVV16_RS08280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BVV16_RS08285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BVV16_RS08305	COG0101	tRNA pseudouridine synthase activity
BVV16_RS08310	COG0135	phosphoribosylanthranilate isomerase activity
BVV16_RS08320	COG0133	tryptophan synthase activity
BVV16_RS08335	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BVV16_RS08340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVV16_RS08400	COG0149	triose-phosphate isomerase activity
BVV16_RS08415	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVV16_RS08425	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVV16_RS08430	COG0649	NAD binding
BVV16_RS08435	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BVV16_RS08440	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BVV16_RS08445	COG1034	ATP synthesis coupled electron transport
BVV16_RS08450	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BVV16_RS08455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVV16_RS08480	COG1007	ATP synthesis coupled electron transport
BVV16_RS08490	COG0779	Required for maturation of 30S ribosomal subunits
BVV16_RS08495	COG0195	Participates in both transcription termination and antitermination
BVV16_RS08500	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BVV16_RS08515	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BVV16_RS08520	COG1185	polyribonucleotide nucleotidyltransferase activity
BVV16_RS08555	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BVV16_RS08565	COG2095	MarC family integral membrane protein
BVV16_RS08580	COG1611	Belongs to the LOG family
BVV16_RS08625	COG4969	Belongs to the N-Me-Phe pilin family
BVV16_RS08630	COG0556	nucleotide-excision repair
BVV16_RS08660	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BVV16_RS08670	COG2986	histidine ammonia-lyase
BVV16_RS08675	COG1228	amidohydrolase
BVV16_RS08720	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BVV16_RS08725	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BVV16_RS08730	COG0077	Prephenate dehydratase
BVV16_RS08730	COG1605	Chorismate mutase
BVV16_RS08735	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BVV16_RS08760	COG3039	Transposase
BVV16_RS08770	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BVV16_RS08785	COG0583	DNA-binding transcription factor activity
BVV16_RS08800	COG2336	PFAM SpoVT AbrB
BVV16_RS08840	COG0840	transmembrane signaling receptor activity
BVV16_RS08865	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BVV16_RS08870	COG4191	Histidine kinase
BVV16_RS08870	COG0784	Response regulator, receiver
BVV16_RS08885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVV16_RS08905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BVV16_RS08920	COG1595	DNA-templated transcription, initiation
BVV16_RS08970	COG2244	polysaccharide biosynthetic process
BVV16_RS09000	COG2264	protein methyltransferase activity
BVV16_RS09010	COG0438	transferase activity, transferring glycosyl groups
BVV16_RS09025	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BVV16_RS09030	COG1132	(ABC) transporter
BVV16_RS09040	COG2271	Major facilitator Superfamily
BVV16_RS09060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVV16_RS09075	COG1253	flavin adenine dinucleotide binding
BVV16_RS09090	COG0306	phosphate transporter
BVV16_RS09120	COG0504	CTP synthase activity
BVV16_RS09125	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BVV16_RS09130	COG0148	phosphopyruvate hydratase activity
BVV16_RS09135	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BVV16_RS09150	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BVV16_RS09160	COG2840	Smr protein MutS2
BVV16_RS09165	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BVV16_RS09170	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BVV16_RS09175	COG1238	metal cluster binding
BVV16_RS09190	COG1534	Rna-binding protein
BVV16_RS09195	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BVV16_RS09205	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BVV16_RS09220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BVV16_RS09225	COG1546	Belongs to the CinA family
BVV16_RS09240	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BVV16_RS09250	COG2137	regulation of response to DNA damage stimulus
BVV16_RS09255	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BVV16_RS09260	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BVV16_RS09315	COG1741	Belongs to the pirin family
BVV16_RS09320	COG0583	DNA-binding transcription factor activity
BVV16_RS09345	COG0352	thiamine-phosphate diphosphorylase activity
BVV16_RS09345	COG0351	phosphomethylpyrimidine kinase
BVV16_RS09355	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BVV16_RS09360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BVV16_RS09375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVV16_RS09385	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BVV16_RS09390	COG3734	2-keto-3-deoxy-galactonokinase
BVV16_RS09400	COG4948	Mandelate Racemase Muconate Lactonizing
BVV16_RS09405	COG0800	Aldolase
BVV16_RS09430	COG1070	Carbohydrate kinase
BVV16_RS09440	COG0477	Major facilitator Superfamily
BVV16_RS09460	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVV16_RS09465	COG1469	GTP cyclohydrolase I activity
BVV16_RS09475	COG0617	tRNA 3'-terminal CCA addition
BVV16_RS09495	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BVV16_RS09525	COG1472	Belongs to the glycosyl hydrolase 3 family
BVV16_RS09545	COG2203	Gaf domain
BVV16_RS09545	COG3706	GGDEF domain
BVV16_RS09545	COG4251	negative regulation of phosphorylation
BVV16_RS09545	COG5001	Diguanylate cyclase
BVV16_RS09555	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BVV16_RS09565	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BVV16_RS09580	COG0671	phosphoesterase, PA-phosphatase related
BVV16_RS09600	COG1794	racemase activity, acting on amino acids and derivatives
BVV16_RS09610	COG0697	spore germination
BVV16_RS09615	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BVV16_RS09640	COG1012	belongs to the aldehyde dehydrogenase family
BVV16_RS09700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BVV16_RS09715	COG0124	histidyl-tRNA synthetase
BVV16_RS09735	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BVV16_RS09750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BVV16_RS09750	COG0131	Imidazoleglycerol-phosphate dehydratase
BVV16_RS09760	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BVV16_RS09770	COG0140	phosphoribosyl-ATP diphosphatase activity
BVV16_RS09770	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BVV16_RS09795	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BVV16_RS09800	COG0235	Class ii aldolase
BVV16_RS09805	COG0531	amino acid
BVV16_RS09810	COG0531	amino acid
BVV16_RS09820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVV16_RS09825	COG0277	FAD linked oxidase domain protein
BVV16_RS09850	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BVV16_RS09900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVV16_RS09905	COG2258	MOSC domain
BVV16_RS09910	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BVV16_RS09915	COG0505	Belongs to the CarA family
BVV16_RS09925	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BVV16_RS09930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BVV16_RS09940	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BVV16_RS09955	COG3279	Response regulator of the LytR AlgR family
BVV16_RS09980	COG0784	Response regulator, receiver
BVV16_RS09980	COG2198	Histidine kinase
BVV16_RS09980	COG2205	protein histidine kinase activity
BVV16_RS09985	COG1024	Enoyl-CoA hydratase
BVV16_RS09990	COG0318	PFAM AMP-dependent synthetase and ligase
BVV16_RS10020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVV16_RS10050	COG0840	transmembrane signaling receptor activity
BVV16_RS10060	COG0835	chemotaxis
BVV16_RS10075	COG0840	transmembrane signaling receptor activity
BVV16_RS10080	COG0840	transmembrane signaling receptor activity
BVV16_RS10085	COG0840	transmembrane signaling receptor activity
BVV16_RS10100	COG0840	transmembrane signaling receptor activity
BVV16_RS10110	COG0840	transmembrane signaling receptor activity
BVV16_RS10115	COG0840	transmembrane signaling receptor activity
BVV16_RS10145	COG0840	transmembrane signaling receptor activity
BVV16_RS10155	COG0745	RESPONSE REGULATOR receiver
BVV16_RS10165	COG0835	chemotaxis
BVV16_RS10170	COG1192	Involved in chromosome partitioning
BVV16_RS10175	COG1360	Flagellar Motor Protein
BVV16_RS10180	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BVV16_RS10200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BVV16_RS10240	COG3039	Transposase
BVV16_RS10305	COG0784	Response regulator, receiver
BVV16_RS10305	COG0643	Histidine kinase
BVV16_RS10305	COG2198	Histidine kinase
BVV16_RS10360	COG1684	flagellar biosynthetic protein fliR
BVV16_RS10375	COG3190	flagellar
BVV16_RS10425	COG1677	Flagellar hook-basal body complex protein FliE
BVV16_RS10460	COG1028	Short-chain dehydrogenase reductase Sdr
BVV16_RS10470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVV16_RS10490	COG2201	protein-glutamate methylesterase activity
BVV16_RS10520	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BVV16_RS10525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BVV16_RS10540	COG1705	Flagellar rod assembly protein muramidase FlgJ
BVV16_RS10540	COG3951	Flagellar rod assembly protein muramidase FlgJ
BVV16_RS10545	COG1706	bacterial-type flagellum-dependent cell motility
BVV16_RS10550	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BVV16_RS10565	COG4787	bacterial-type flagellum-dependent cell motility
BVV16_RS10575	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BVV16_RS10580	COG1558	bacterial-type flagellum-dependent cell motility
BVV16_RS10590	COG0784	Response regulator, receiver
BVV16_RS10590	COG0835	chemotaxis
BVV16_RS10610	COG5002	protein histidine kinase activity
BVV16_RS10620	COG4585	Histidine kinase
BVV16_RS10655	COG0482	sulfurtransferase activity
BVV16_RS10670	COG0542	response to heat
BVV16_RS10695	COG0492	ferredoxin-NADP+ reductase activity
BVV16_RS10700	COG1674	ftsk spoiiie
BVV16_RS10725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BVV16_RS10745	COG0038	chloride channel
BVV16_RS10750	COG0183	Belongs to the thiolase family
BVV16_RS10755	COG1024	Enoyl-CoA hydratase
BVV16_RS10755	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVV16_RS10770	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BVV16_RS10790	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVV16_RS10795	COG1160	GTP binding
BVV16_RS10800	COG0303	'Molybdopterin
BVV16_RS10810	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BVV16_RS10820	COG2826	transposase and inactivated derivatives, IS30 family
BVV16_RS10830	COG3039	Transposase
BVV16_RS10855	COG0746	molybdenum cofactor guanylyltransferase activity
BVV16_RS10880	COG1648	precorrin-2 dehydrogenase activity
BVV16_RS10880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BVV16_RS10920	COG3039	Transposase
BVV16_RS10945	COG5001	Diguanylate cyclase
BVV16_RS10955	COG3039	Transposase
BVV16_RS10965	COG4566	intracellular signal transduction
BVV16_RS11025	COG2201	protein-glutamate methylesterase activity
BVV16_RS11095	COG1024	Enoyl-CoA hydratase
BVV16_RS11100	COG1024	Enoyl-CoA hydratase
BVV16_RS11110	COG1024	Enoyl-CoA hydratase
BVV16_RS11125	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BVV16_RS11150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVV16_RS11155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVV16_RS11215	COG1858	cytochrome C peroxidase
BVV16_RS11245	COG0515	serine threonine protein kinase
BVV16_RS11250	COG0631	protein serine/threonine phosphatase activity
BVV16_RS11315	COG3039	Transposase
BVV16_RS11400	COG3039	Transposase
BVV16_RS11415	COG2154	pterin-4-alpha-carbinolamine dehydratase
BVV16_RS11430	COG3064	Membrane
BVV16_RS11440	COG1530	ribonuclease E activity
BVV16_RS11455	COG1054	Belongs to the UPF0176 family
BVV16_RS11475	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BVV16_RS11515	COG0322	excinuclease ABC activity
BVV16_RS11525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BVV16_RS11535	COG1663	tetraacyldisaccharide 4'-kinase activity
BVV16_RS11550	COG0811	peptide transport
BVV16_RS11575	COG4591	ABC-type transport system involved in lipoprotein release permease component
BVV16_RS11590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BVV16_RS11605	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BVV16_RS11620	COG0354	folic acid binding
BVV16_RS11635	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BVV16_RS11645	COG0363	glucosamine-6-phosphate deaminase activity
BVV16_RS11650	COG0129	dihydroxy-acid dehydratase activity
BVV16_RS11655	COG0800	Aldolase
BVV16_RS11735	COG0784	Response regulator, receiver
BVV16_RS11735	COG2205	protein histidine kinase activity
BVV16_RS11750	COG2183	response to ionizing radiation
BVV16_RS11760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVV16_RS11760	COG0723	plastoquinol--plastocyanin reductase activity
BVV16_RS11775	COG3243	poly(R)-hydroxyalkanoic acid synthase
BVV16_RS11785	COG1183	phosphatidylcholine synthase activity
BVV16_RS11790	COG1028	Short-chain dehydrogenase reductase Sdr
BVV16_RS11805	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BVV16_RS11815	COG0668	transmembrane transport
BVV16_RS11835	COG1914	H( )-stimulated, divalent metal cation uptake system
BVV16_RS11865	COG0583	DNA-binding transcription factor activity
BVV16_RS11890	COG0583	DNA-binding transcription factor activity
BVV16_RS11895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BVV16_RS11900	COG3002	Belongs to the UPF0753 family
BVV16_RS11905	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BVV16_RS11905	COG0519	Catalyzes the synthesis of GMP from XMP
BVV16_RS11915	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BVV16_RS11930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BVV16_RS11940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVV16_RS11945	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BVV16_RS11955	COG0776	regulation of translation
BVV16_RS11960	COG0539	negative regulation of cytoplasmic translation
BVV16_RS11965	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BVV16_RS11980	COG2957	Belongs to the agmatine deiminase family
BVV16_RS11990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVV16_RS12015	COG0395	ABC-type sugar transport system, permease component
BVV16_RS12020	COG1175	transmembrane transport
BVV16_RS12050	COG2350	Protein conserved in bacteria
BVV16_RS12055	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BVV16_RS12060	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BVV16_RS12065	COG1187	pseudouridine synthase activity
BVV16_RS12085	COG0436	Aminotransferase
BVV16_RS12090	COG4133	protoheme IX ABC transporter activity
BVV16_RS12140	COG1278	Cold shock
BVV16_RS12150	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BVV16_RS12155	COG4988	ABC transporter
BVV16_RS12165	COG1271	oxidase subunit
BVV16_RS12220	COG0165	Argininosuccinate lyase
BVV16_RS12235	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BVV16_RS12240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVV16_RS12245	COG0137	argininosuccinate synthase activity
BVV16_RS12250	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BVV16_RS12265	COG2166	iron-sulfur cluster assembly
BVV16_RS12290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BVV16_RS12305	COG4302	ethanolamine ammonia-lyase activity
BVV16_RS12320	COG4677	pectinesterase activity
BVV16_RS12325	COG2826	transposase and inactivated derivatives, IS30 family
BVV16_RS12350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BVV16_RS12355	COG0402	S-adenosylhomocysteine deaminase activity
BVV16_RS12375	COG1509	lysine 2,3-aminomutase activity
BVV16_RS12380	COG5001	Diguanylate cyclase
BVV16_RS12380	COG3300	MHYT domain
BVV16_RS12395	COG0483	inositol monophosphate 1-phosphatase activity
BVV16_RS12400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BVV16_RS12425	COG0488	(ABC) transporter
BVV16_RS12430	COG0513	Belongs to the DEAD box helicase family
BVV16_RS12440	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BVV16_RS12450	COG0625	glutathione transferase activity
BVV16_RS12460	COG1671	Belongs to the UPF0178 family
BVV16_RS12465	COG4681	YaeQ
BVV16_RS12470	COG2081	HI0933 family
BVV16_RS12475	COG5001	Diguanylate cyclase
BVV16_RS12475	COG1716	ATPase activity
BVV16_RS12480	COG0501	Belongs to the peptidase M48B family
BVV16_RS12490	COG1028	Short-chain dehydrogenase reductase Sdr
BVV16_RS12510	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BVV16_RS12515	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVV16_RS12520	COG0802	atpase or kinase
BVV16_RS12525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BVV16_RS12525	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BVV16_RS12530	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BVV16_RS12550	COG3039	Transposase
BVV16_RS12560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BVV16_RS12610	COG0835	chemotaxis
BVV16_RS12615	COG0840	transmembrane signaling receptor activity
BVV16_RS12645	COG2969	positive regulation of protein catabolic process
BVV16_RS12650	COG0625	glutathione transferase activity
BVV16_RS12655	COG2857	Cytochrome c1
BVV16_RS12660	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BVV16_RS12665	COG0723	plastoquinol--plastocyanin reductase activity
BVV16_RS12675	COG0741	lytic transglycosylase activity
BVV16_RS12700	COG1702	phosphate starvation-inducible protein PhoH
BVV16_RS12720	COG4535	Mg2 and Co2 transporter CorC
BVV16_RS12735	COG1012	belongs to the aldehyde dehydrogenase family
BVV16_RS12740	COG1177	transmembrane transport
BVV16_RS12745	COG1176	ABC-type spermidine putrescine transport system, permease component I
BVV16_RS12755	COG3842	ATPase activity
BVV16_RS12785	COG3039	Transposase
BVV16_RS12810	COG0174	glutamine synthetase
BVV16_RS12815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVV16_RS12825	COG0477	Major facilitator Superfamily
BVV16_RS12835	COG0243	molybdopterin cofactor binding
BVV16_RS12845	COG2223	nitrite transmembrane transporter activity
BVV16_RS12855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BVV16_RS12860	COG1121	(ABC) transporter
BVV16_RS12870	COG2733	membrane
BVV16_RS12875	COG0784	Response regulator, receiver
BVV16_RS12875	COG2205	protein histidine kinase activity
BVV16_RS12875	COG5002	protein histidine kinase activity
BVV16_RS12885	COG3039	Transposase
BVV16_RS12890	COG2902	Dehydrogenase
BVV16_RS12900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVV16_RS12905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVV16_RS12920	COG1609	Transcriptional regulator
BVV16_RS12925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BVV16_RS12925	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVV16_RS12930	COG1105	Belongs to the carbohydrate kinase PfkB family
BVV16_RS12935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVV16_RS12935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVV16_RS12960	COG2826	transposase and inactivated derivatives, IS30 family
BVV16_RS12995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BVV16_RS13005	COG1862	Preprotein translocase
BVV16_RS13010	COG0343	queuine tRNA-ribosyltransferase activity
BVV16_RS13075	COG0405	Gamma-glutamyltransferase
BVV16_RS13080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BVV16_RS13095	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BVV16_RS13100	COG0742	ribosomal rna small subunit methyltransferase
BVV16_RS13105	COG0326	Molecular chaperone. Has ATPase activity
BVV16_RS13150	COG4206	TonB-dependent receptor
BVV16_RS13205	COG0531	amino acid
BVV16_RS13220	COG0006	proline dipeptidase activity
BVV16_RS13230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVV16_RS13245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVV16_RS13250	COG3938	Belongs to the proline racemase family
BVV16_RS13260	COG0552	protein localization to endoplasmic reticulum
BVV16_RS13275	COG1194	a g-specific adenine glycosylase
BVV16_RS13285	COG4191	Histidine kinase
BVV16_RS13285	COG0784	Response regulator, receiver
BVV16_RS13290	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BVV16_RS13315	COG3040	lipid binding
BVV16_RS13325	COG1960	acyl-CoA dehydrogenase activity
BVV16_RS13335	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BVV16_RS13365	COG0438	transferase activity, transferring glycosyl groups
BVV16_RS13375	COG0438	transferase activity, transferring glycosyl groups
BVV16_RS13380	COG0438	transferase activity, transferring glycosyl groups
BVV16_RS13435	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BVV16_RS13450	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BVV16_RS13475	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BVV16_RS13490	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BVV16_RS13495	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BVV16_RS13500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BVV16_RS13505	COG3115	cell septum assembly
BVV16_RS13525	COG0360	Binds together with S18 to 16S ribosomal RNA
BVV16_RS13530	COG0316	Belongs to the HesB IscA family
BVV16_RS13565	COG0288	reversible hydration of carbon dioxide
BVV16_RS13590	COG3844	kynureninase activity
BVV16_RS13600	COG2925	Exonuclease
BVV16_RS13610	COG0667	Aldo Keto reductase
BVV16_RS13640	COG0116	Belongs to the methyltransferase superfamily
BVV16_RS13640	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BVV16_RS13685	COG0494	nUDIX hydrolase
BVV16_RS13695	COG1024	Enoyl-CoA hydratase
BVV16_RS13705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BVV16_RS13710	COG0659	secondary active sulfate transmembrane transporter activity
BVV16_RS13720	COG3039	Transposase
BVV16_RS13740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BVV16_RS13745	COG0573	inorganic phosphate transmembrane transporter activity
BVV16_RS13760	COG0704	Plays a role in the regulation of phosphate uptake
BVV16_RS13770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BVV16_RS13780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVV16_RS13795	COG0557	exoribonuclease II activity
BVV16_RS13825	COG1960	acyl-CoA dehydrogenase activity
BVV16_RS13830	COG2226	methyltransferase
BVV16_RS13835	COG0646	methionine synthase
BVV16_RS13835	COG1410	methionine synthase
BVV16_RS13840	COG1410	methionine synthase
BVV16_RS13840	COG0646	methionine synthase
BVV16_RS13850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVV16_RS13860	COG1609	Transcriptional regulator
BVV16_RS13875	COG2900	Belongs to the SlyX family
BVV16_RS13890	COG0386	Belongs to the glutathione peroxidase family
BVV16_RS13900	COG1725	Transcriptional regulator
BVV16_RS13905	COG1131	(ABC) transporter
BVV16_RS13945	COG3039	Transposase
BVV16_RS13955	COG2826	transposase and inactivated derivatives, IS30 family
BVV16_RS13980	COG2850	peptidyl-arginine hydroxylation
BVV16_RS14015	COG1132	(ABC) transporter
BVV16_RS14045	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BVV16_RS14055	COG0484	heat shock protein binding
BVV16_RS14060	COG0443	Heat shock 70 kDa protein
BVV16_RS14065	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BVV16_RS14075	COG0497	DNA recombination
BVV16_RS14085	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVV16_RS14095	COG2914	Belongs to the UPF0125 (RnfH) family
BVV16_RS14105	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BVV16_RS14130	COG3039	Transposase
BVV16_RS14165	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BVV16_RS14180	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BVV16_RS14190	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BVV16_RS14195	COG0174	glutamine synthetase
BVV16_RS14275	COG0415	Belongs to the DNA photolyase family
BVV16_RS14280	COG0305	Participates in initiation and elongation during chromosome replication
BVV16_RS14290	COG0367	asparagine synthase
BVV16_RS14320	COG0084	hydrolase, TatD family'
BVV16_RS14325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BVV16_RS14365	COG0840	transmembrane signaling receptor activity
BVV16_RS14380	COG3039	Transposase
BVV16_RS14390	COG3039	Transposase
BVV16_RS14425	COG0386	Belongs to the glutathione peroxidase family
BVV16_RS14525	COG2814	Major facilitator Superfamily
BVV16_RS14530	COG1566	PFAM secretion protein HlyD family protein
BVV16_RS14545	COG2207	Transcriptional regulator
BVV16_RS14575	COG4774	siderophore transport
BVV16_RS14585	COG0367	asparagine synthase
BVV16_RS14590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVV16_RS14600	COG1393	Belongs to the ArsC family
BVV16_RS14660	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BVV16_RS14675	COG0233	cytoplasmic translational termination
BVV16_RS14685	COG0575	Belongs to the CDS family
BVV16_RS14690	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BVV16_RS14695	COG0750	zinc metalloprotease
BVV16_RS14715	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BVV16_RS14720	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVV16_RS14740	COG0825	malonyl-CoA metabolic process
BVV16_RS14765	COG1981	membrane
BVV16_RS14815	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BVV16_RS14830	COG2040	homocysteine
BVV16_RS14835	COG0833	amino acid
BVV16_RS14840	COG0346	lactoylglutathione lyase activity
BVV16_RS14850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVV16_RS14850	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVV16_RS14860	COG2878	Part of a membrane complex involved in electron transport
BVV16_RS14880	COG1595	DNA-templated transcription, initiation
BVV16_RS14905	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BVV16_RS14920	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BVV16_RS14925	COG0251	oxidation-reduction process
BVV16_RS14935	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BVV16_RS14935	COG0392	lysyltransferase activity
BVV16_RS14975	COG2814	Major facilitator Superfamily
BVV16_RS14980	COG1902	pentaerythritol trinitrate reductase activity
BVV16_RS14995	COG2824	Alkylphosphonate utilization operon protein PhnA
BVV16_RS15005	COG1047	Peptidyl-prolyl cis-trans
BVV16_RS15050	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BVV16_RS15065	COG1451	nucleotide metabolic process
BVV16_RS15085	COG0183	Belongs to the thiolase family
BVV16_RS15115	COG1793	dna ligase
BVV16_RS15115	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BVV16_RS15125	COG1793	dna ligase
BVV16_RS15130	COG1201	RNA secondary structure unwinding
BVV16_RS15150	COG1278	Cold shock
BVV16_RS15155	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BVV16_RS15160	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BVV16_RS15170	COG3046	protein related to deoxyribodipyrimidine photolyase
BVV16_RS15175	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
BVV16_RS15180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BVV16_RS15185	COG2954	triphosphatase activity
BVV16_RS15200	COG1381	Involved in DNA repair and RecF pathway recombination
BVV16_RS15230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVV16_RS15245	COG1024	Enoyl-CoA hydratase
BVV16_RS15245	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVV16_RS15265	COG1024	Enoyl-CoA hydratase
BVV16_RS15270	COG1960	acyl-CoA dehydrogenase activity
BVV16_RS15345	COG2353	YceI-like domain
BVV16_RS15370	COG1760	l-serine dehydratase
BVV16_RS15380	COG0626	cystathionine gamma-synthase activity
BVV16_RS15385	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVV16_RS15390	COG0739	heme binding
BVV16_RS15400	COG1272	protein, Hemolysin III
BVV16_RS15430	COG0516	GMP reductase activity
BVV16_RS15430	COG0517	IMP dehydrogenase activity
BVV16_RS15435	COG0463	Glycosyl transferase, family 2
BVV16_RS15445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BVV16_RS15455	COG4771	TonB-dependent receptor
BVV16_RS15460	COG1309	transcriptional regulator
BVV16_RS15470	COG1960	acyl-CoA dehydrogenase activity
BVV16_RS15500	COG0509	glycine decarboxylation via glycine cleavage system
BVV16_RS15515	COG0330	HflC and HflK could
BVV16_RS15525	COG1742	UPF0060 membrane protein
BVV16_RS15530	COG3956	TIGRFAM MazG family protein
BVV16_RS15540	COG0494	nUDIX hydrolase
BVV16_RS15550	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BVV16_RS15555	COG0837	glucose binding
BVV16_RS15570	COG3858	chitin binding
BVV16_RS15570	COG1388	LysM domain
BVV16_RS15590	COG1472	Belongs to the glycosyl hydrolase 3 family
BVV16_RS15635	COG3537	Alpha-1,2-mannosidase
BVV16_RS15680	COG3142	Participates in the control of copper homeostasis
BVV16_RS15685	COG1446	asparaginase
BVV16_RS15695	COG2304	oxidoreductase activity
BVV16_RS15720	COG0784	Response regulator, receiver
BVV16_RS15720	COG2198	Histidine kinase
BVV16_RS15720	COG0643	Histidine kinase
BVV16_RS15725	COG0840	transmembrane signaling receptor activity
BVV16_RS15730	COG0835	chemotaxis
BVV16_RS15745	COG0189	ligase activity
BVV16_RS15755	COG1397	ADP-ribosylglycohydrolase
BVV16_RS15765	COG1199	ATP-dependent helicase activity
BVV16_RS15775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVV16_RS15780	COG1215	transferase activity, transferring glycosyl groups
BVV16_RS15790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BVV16_RS15840	COG1643	Atp-dependent helicase
BVV16_RS15845	COG0783	Belongs to the Dps family
BVV16_RS15860	COG0514	ATP-dependent DNA helicase (RecQ)
BVV16_RS15875	COG3039	Transposase
BVV16_RS15890	COG1187	pseudouridine synthase activity
BVV16_RS15930	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BVV16_RS15940	COG0602	queuosine metabolic process
BVV16_RS15950	COG2885	chlorophyll binding
BVV16_RS15955	COG0823	Involved in the tonB-independent uptake of proteins
BVV16_RS15965	COG0848	biopolymer transport protein
BVV16_RS15975	COG0824	Thioesterase
BVV16_RS15980	COG2255	four-way junction helicase activity
BVV16_RS15995	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BVV16_RS16015	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BVV16_RS16030	COG0477	Major facilitator Superfamily
BVV16_RS16065	COG0488	(ABC) transporter
BVV16_RS16095	COG4651	solute:proton antiporter activity
BVV16_RS16095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BVV16_RS16140	COG4772	TonB-dependent receptor
BVV16_RS16150	COG4264	IucA IucC family
BVV16_RS16165	COG0019	diaminopimelate decarboxylase activity
BVV16_RS16220	COG4206	TonB-dependent receptor
BVV16_RS16250	COG0542	response to heat
BVV16_RS16275	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BVV16_RS16285	COG0534	Mate efflux family protein
BVV16_RS16300	COG0336	Belongs to the RNA methyltransferase TrmD family
BVV16_RS16305	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BVV16_RS16310	COG0228	four-way junction DNA binding
BVV16_RS16335	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BVV16_RS16340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BVV16_RS16380	COG2172	sigma factor antagonist activity
BVV16_RS16385	COG1366	Belongs to the anti-sigma-factor antagonist family
BVV16_RS16390	COG1366	Belongs to the anti-sigma-factor antagonist family
BVV16_RS16400	COG0326	Molecular chaperone. Has ATPase activity
BVV16_RS16405	COG2207	Transcriptional regulator
BVV16_RS16470	COG3039	Transposase
BVV16_RS16495	COG3209	COG3209 Rhs family protein
BVV16_RS16515	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BVV16_RS16520	COG1845	cytochrome c oxidase, subunit III
BVV16_RS16525	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BVV16_RS16540	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BVV16_RS16545	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BVV16_RS16560	COG0728	peptidoglycan biosynthetic process
BVV16_RS16565	COG0268	Binds directly to 16S ribosomal RNA
BVV16_RS16570	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BVV16_RS16575	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BVV16_RS16585	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BVV16_RS16590	COG0824	Thioesterase
BVV16_RS16605	COG1946	Acyl-CoA thioesterase
BVV16_RS16615	COG1595	DNA-templated transcription, initiation
BVV16_RS16630	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BVV16_RS16670	COG1877	trehalose-phosphatase activity
BVV16_RS16675	COG3387	PFAM Glycoside hydrolase 15-related
BVV16_RS16715	COG0564	pseudouridine synthase activity
BVV16_RS16720	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVV16_RS16725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVV16_RS16725	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BVV16_RS16740	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BVV16_RS16745	COG0045	succinate-CoA ligase (ADP-forming) activity
BVV16_RS16785	COG2194	sulfuric ester hydrolase activity
BVV16_RS16790	COG4969	Belongs to the N-Me-Phe pilin family
BVV16_RS16800	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BVV16_RS16805	COG0237	dephospho-CoA kinase activity
BVV16_RS16810	COG2205	protein histidine kinase activity
BVV16_RS16815	COG0745	RESPONSE REGULATOR receiver
BVV16_RS16835	COG3039	Transposase
BVV16_RS16850	COG3039	Transposase
BVV16_RS16880	COG3039	Transposase
BVV16_RS16905	COG2022	thiamine diphosphate biosynthetic process
BVV16_RS16920	COG0471	metal ion transport
BVV16_RS16920	COG3273	potassium ion transport
BVV16_RS16950	COG1970	mechanosensitive ion channel activity
BVV16_RS16985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVV16_RS16995	COG0308	aminopeptidase N
BVV16_RS17000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVV16_RS17010	COG2895	sulfate adenylyltransferase (ATP) activity
BVV16_RS17010	COG0529	Catalyzes the synthesis of activated sulfate
BVV16_RS17015	COG0175	sulfate reduction
BVV16_RS17020	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BVV16_RS17025	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVV16_RS17030	COG0175	sulfate reduction
BVV16_RS17050	COG2198	Histidine kinase
BVV16_RS17050	COG2205	protein histidine kinase activity
BVV16_RS17050	COG0784	Response regulator, receiver
BVV16_RS17090	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BVV16_RS17095	COG3588	fructose-bisphosphate aldolase
BVV16_RS17100	COG0469	pyruvate kinase activity
BVV16_RS17130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BVV16_RS17145	COG3453	Protein conserved in bacteria
BVV16_RS17145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVV16_RS17150	COG0725	ABC transporter, periplasmic molybdate-binding protein
BVV16_RS17155	COG4149	molybdate abc transporter
BVV16_RS17160	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BVV16_RS17180	COG0642	Histidine kinase
BVV16_RS17195	COG1028	Short-chain dehydrogenase reductase Sdr
BVV16_RS17205	COG1022	Amp-dependent synthetase and ligase
BVV16_RS17230	COG1376	ErfK ybiS ycfS ynhG family protein
BVV16_RS17235	COG0739	heme binding
BVV16_RS17250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BVV16_RS17255	COG1301	dicarboxylic acid transport
BVV16_RS17275	COG2304	oxidoreductase activity
BVV16_RS17295	COG0714	Associated with various cellular activities
BVV16_RS17330	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BVV16_RS17365	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BVV16_RS17375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BVV16_RS17395	COG1561	YicC-like family, N-terminal region
BVV16_RS17400	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BVV16_RS17415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BVV16_RS17445	COG0006	proline dipeptidase activity
BVV16_RS17470	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BVV16_RS17490	COG2912	Transglutaminase-like superfamily
BVV16_RS17495	COG1773	rubredoxin
BVV16_RS17500	COG0352	thiamine-phosphate diphosphorylase activity
BVV16_RS17510	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BVV16_RS17525	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BVV16_RS17565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BVV16_RS17590	COG0671	phosphoesterase, PA-phosphatase related
BVV16_RS17605	COG3781	membrane
BVV16_RS17615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BVV16_RS17630	COG3039	Transposase
BVV16_RS17645	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BVV16_RS17655	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BVV16_RS17680	COG3710	Transcriptional regulator
BVV16_RS17685	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BVV16_RS17695	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BVV16_RS17725	COG2226	methyltransferase
BVV16_RS17730	COG0066	3-isopropylmalate dehydratase activity
BVV16_RS17735	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BVV16_RS17755	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BVV16_RS17760	COG1538	Outer membrane efflux protein
BVV16_RS17765	COG1519	Transferase
BVV16_RS17770	COG1560	Kdo2-lipid A biosynthetic process
BVV16_RS17800	COG2826	transposase and inactivated derivatives, IS30 family
BVV16_RS17835	COG0281	malic enzyme
BVV16_RS17835	COG0280	phosphate acetyltransferase
BVV16_RS17855	COG4191	Histidine kinase
BVV16_RS17870	COG0583	DNA-binding transcription factor activity
BVV16_RS17890	COG2197	response regulator
BVV16_RS17900	COG0642	Histidine kinase
BVV16_RS17920	COG2851	Citrate transporter
BVV16_RS17925	COG1028	Short-chain dehydrogenase reductase Sdr
BVV16_RS17935	COG1609	Transcriptional regulator
BVV16_RS17940	COG2211	Major facilitator Superfamily
BVV16_RS17970	COG0436	Aminotransferase
BVV16_RS17990	COG0726	polysaccharide deacetylase
BVV16_RS17995	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BVV16_RS18015	COG0402	S-adenosylhomocysteine deaminase activity
BVV16_RS18065	COG0242	peptide deformylase activity
BVV16_RS18070	COG3039	Transposase
BVV16_RS18105	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BVV16_RS18165	COG2188	Transcriptional regulator
BVV16_RS18180	COG1450	Type ii and iii secretion system protein
BVV16_RS18195	COG3166	PFAM Fimbrial assembly family protein
BVV16_RS18200	COG3156	type II secretion system protein K
BVV16_RS18205	COG4795	General secretion pathway protein
BVV16_RS18210	COG2165	general secretion pathway protein
BVV16_RS18215	COG4970	Tfp pilus assembly protein FimT
BVV16_RS18220	COG2165	general secretion pathway protein
BVV16_RS18225	COG1459	type II secretion system
BVV16_RS18235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BVV16_RS18240	COG1404	Belongs to the peptidase S8 family
BVV16_RS18245	COG5295	Hep Hag repeat protein
BVV16_RS18255	COG0047	phosphoribosylformylglycinamidine synthase activity
BVV16_RS18255	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BVV16_RS18265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BVV16_RS18270	COG4974	Belongs to the 'phage' integrase family
BVV16_RS18285	COG0795	lipopolysaccharide-transporting ATPase activity
BVV16_RS18295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BVV16_RS18320	COG0525	valine-tRNA ligase activity
BVV16_RS18350	COG2826	transposase and inactivated derivatives, IS30 family
BVV16_RS18360	COG2826	transposase and inactivated derivatives, IS30 family
BVV16_RS18385	COG1183	phosphatidylcholine synthase activity
BVV16_RS18395	COG0442	prolyl-tRNA aminoacylation
BVV16_RS18410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BVV16_RS18415	COG1127	ABC transporter
BVV16_RS18420	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BVV16_RS18420	COG3218	ABC-type transport auxiliary lipoprotein component
BVV16_RS18465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVV16_RS18470	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BVV16_RS18470	COG0662	Cupin 2, conserved barrel domain protein
BVV16_RS18495	COG2086	electron transfer activity
BVV16_RS18580	COG0626	cystathionine gamma-synthase activity
BVV16_RS18610	COG0625	glutathione transferase activity
BVV16_RS18625	COG0513	Belongs to the DEAD box helicase family
BVV16_RS18635	COG0720	synthase
BVV16_RS18645	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BVV16_RS18650	COG1956	GAF domain-containing protein
BVV16_RS18660	COG3039	Transposase
BVV16_RS18665	COG0546	phosphoglycolate phosphatase activity
BVV16_RS18695	COG0339	signal peptide processing
BVV16_RS18745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BVV16_RS18810	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BVV16_RS18815	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BVV16_RS18820	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BVV16_RS18830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BVV16_RS18840	COG0356	it plays a direct role in the translocation of protons across the membrane
BVV16_RS18860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVV16_RS18870	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVV16_RS18905	COG2011	ABC-type metal ion transport system permease component
BVV16_RS18915	COG0697	spore germination
BVV16_RS18955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BVV16_RS18965	COG2813	Specifically methylates the guanine in position
BVV16_RS18995	COG2205	protein histidine kinase activity
BVV16_RS18995	COG2202	Pas domain
BVV16_RS19020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVV16_RS19080	COG0745	RESPONSE REGULATOR receiver
BVV16_RS19095	COG1404	Belongs to the peptidase S8 family
BVV16_RS19110	COG0842	Transport permease protein
BVV16_RS19115	COG1131	(ABC) transporter
BVV16_RS19120	COG0025	NhaP-type Na H and K H
BVV16_RS19130	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BVV16_RS19140	COG1573	uracil-dna glycosylase
BVV16_RS19150	COG3384	dioxygenase
BVV16_RS19165	COG0667	Aldo Keto reductase
BVV16_RS19180	COG3590	peptidase
BVV16_RS19200	COG0531	amino acid
BVV16_RS19225	COG3685	Protein conserved in bacteria
BVV16_RS19230	COG3546	catalase activity
BVV16_RS19255	COG3039	Transposase
BVV16_RS19285	COG1271	oxidase subunit
BVV16_RS19290	COG1294	oxidase, subunit
BVV16_RS19325	COG1063	alcohol dehydrogenase
BVV16_RS19420	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BVV16_RS19420	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BVV16_RS19430	COG1473	amidohydrolase
BVV16_RS19435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVV16_RS19440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVV16_RS19465	COG5383	Protein conserved in bacteria
BVV16_RS19515	COG3023	N-Acetylmuramoyl-L-alanine amidase
BVV16_RS19525	COG4948	Mandelate Racemase Muconate Lactonizing
BVV16_RS19550	COG0531	amino acid
BVV16_RS19570	COG4682	membrane
BVV16_RS19575	COG2133	pyrroloquinoline quinone binding
BVV16_RS19595	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BVV16_RS19600	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BVV16_RS19610	COG1610	YqeY-like protein
BVV16_RS19630	COG1295	ribonuclease BN
BVV16_RS19635	COG0358	DNA primase activity
BVV16_RS19705	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BVV16_RS19720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BVV16_RS19780	COG0739	heme binding
BVV16_RS19795	COG2211	Major facilitator Superfamily
BVV16_RS19800	COG0708	Exodeoxyribonuclease III
BVV16_RS19815	COG1192	Involved in chromosome partitioning
BVV16_RS19820	COG1475	DNA binding
BVV16_RS19835	COG0463	Glycosyl transferase, family 2
BVV16_RS19860	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BVV16_RS19885	COG4221	oxidoreductase activity
BVV16_RS19925	COG1166	arginine decarboxylase activity
BVV16_RS19930	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BVV16_RS19975	COG0606	chelatase, subunit chli
BVV16_RS20000	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BVV16_RS20020	COG3039	Transposase
BVV16_RS20080	COG1090	epimerase
BVV16_RS20090	COG0642	Histidine kinase
BVV16_RS20105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVV16_RS20140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BVV16_RS20150	COG1595	DNA-templated transcription, initiation
BVV16_RS20155	COG0753	catalase activity
BVV16_RS20180	COG0697	spore germination
BVV16_RS20205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVV16_RS20210	COG0180	Tryptophanyl-tRNA synthetase
BVV16_RS20215	COG3237	CsbD-like
BVV16_RS20230	COG0010	Belongs to the arginase family
BVV16_RS20250	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BVV16_RS20265	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BVV16_RS20270	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BVV16_RS20270	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BVV16_RS20280	COG3228	Belongs to the MtfA family
BVV16_RS20310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVV16_RS20365	COG3039	Transposase
BVV16_RS20370	COG1566	PFAM secretion protein HlyD family protein
BVV16_RS20385	COG1199	ATP-dependent helicase activity
BVV16_RS20430	COG0583	DNA-binding transcription factor activity
BVV16_RS20490	COG2826	transposase and inactivated derivatives, IS30 family
BVV16_RS20520	COG4555	ABC transporter
BVV16_RS20530	COG1476	TRANSCRIPTIONal
BVV16_RS20550	COG1230	cation diffusion facilitator family transporter
BVV16_RS20555	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BVV16_RS20560	COG1131	(ABC) transporter
BVV16_RS20565	COG0842	Transport permease protein
BVV16_RS20575	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BVV16_RS20630	COG2951	lytic endotransglycosylase activity
BVV16_RS20650	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVV16_RS20660	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVV16_RS20675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVV16_RS20675	COG1042	CoA-binding domain protein
BVV16_RS20675	COG0045	succinate-CoA ligase (ADP-forming) activity
BVV16_RS20685	COG2239	Acts as a magnesium transporter
BVV16_RS20710	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BVV16_RS20715	COG3387	PFAM Glycoside hydrolase 15-related
BVV16_RS20730	COG3100	YcgL domain-containing protein
BVV16_RS20735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVV16_RS20745	COG0463	Glycosyl transferase, family 2
BVV16_RS20760	COG1028	Short-chain dehydrogenase reductase Sdr
BVV16_RS20790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BVV16_RS20805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVV16_RS20845	COG0408	coproporphyrinogen oxidase activity
BVV16_RS20920	COG0210	DNA helicase
BVV16_RS20940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVV16_RS20955	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BVV16_RS20970	COG2159	amidohydrolase
BVV16_RS21000	COG0357	Ribosomal RNA small subunit methyltransferase G
BVV16_RS21005	COG3540	Alkaline phosphatase
BVV16_RS21015	COG2091	lysine biosynthetic process via aminoadipic acid
BVV16_RS21030	COG0708	Exodeoxyribonuclease III
BVV16_RS21045	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVV16_RS21050	COG3162	membrane
BVV16_RS21105	COG1028	Short-chain dehydrogenase reductase Sdr
BVV16_RS21110	COG0179	Fumarylacetoacetate (FAA) hydrolase
BVV16_RS21120	COG4948	Mandelate Racemase Muconate Lactonizing
BVV16_RS21130	COG3039	Transposase
BVV16_RS21135	COG3254	rhamnose metabolic process
BVV16_RS21140	COG0738	Major facilitator superfamily
BVV16_RS21145	COG1414	Transcriptional regulator
BVV16_RS21155	COG2205	protein histidine kinase activity
BVV16_RS21165	COG3459	Glycosyltransferase 36 associated
BVV16_RS21170	COG2211	Major facilitator Superfamily
BVV16_RS21175	COG3265	gluconokinase activity
BVV16_RS21180	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVV16_RS21215	COG3039	Transposase
BVV16_RS21225	COG3039	Transposase
BVV16_RS21230	COG2911	Protein conserved in bacteria
BVV16_RS21235	COG0729	surface antigen
BVV16_RS21240	COG4771	TonB-dependent receptor
BVV16_RS21245	COG0457	Tetratricopeptide repeat
BVV16_RS21255	COG0752	glycyl-tRNA synthetase alpha subunit
BVV16_RS21260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BVV16_RS21275	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BVV16_RS21275	COG0519	Catalyzes the synthesis of GMP from XMP
BVV16_RS21285	COG0805	protein transport
BVV16_RS21290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVV16_RS21295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVV16_RS21305	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BVV16_RS21335	COG2974	May be involved in recombination
BVV16_RS21340	COG0037	tRNA processing
BVV16_RS21360	COG3661	Belongs to the glycosyl hydrolase 67 family
BVV16_RS21370	COG4948	Mandelate Racemase Muconate Lactonizing
BVV16_RS21380	COG1472	Belongs to the glycosyl hydrolase 3 family
BVV16_RS21385	COG0246	Mannitol dehydrogenase
BVV16_RS21420	COG2826	transposase and inactivated derivatives, IS30 family
BVV16_RS21445	COG3693	PFAM glycoside hydrolase, family 10
BVV16_RS21470	COG2211	Major facilitator Superfamily
BVV16_RS21485	COG3039	Transposase
BVV16_RS21520	COG2937	Belongs to the GPAT DAPAT family
BVV16_RS21565	COG0284	orotidine-5'-phosphate decarboxylase activity
BVV16_RS21570	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BVV16_RS21575	COG3132	Protein of unknown function, DUF480
BVV16_RS21590	COG0210	DNA helicase
BVV16_RS21605	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BVV16_RS21615	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BVV16_RS21670	COG0676	glucose-6-phosphate 1-epimerase activity
BVV16_RS21685	COG0730	response to heat
BVV16_RS21720	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BVV16_RS21725	COG0302	gtp cyclohydrolase
BVV16_RS21755	COG2826	transposase and inactivated derivatives, IS30 family
BVV16_RS21765	COG0477	Major facilitator Superfamily
BVV16_RS21780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVV16_RS21825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVV16_RS21885	COG3237	CsbD-like
BVV16_RS21915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVV16_RS21945	COG1304	FMN binding
BVV16_RS21970	COG4772	TonB-dependent receptor
BVV16_RS21980	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BVV16_RS22010	COG3039	Transposase
BVV16_RS22060	COG0564	pseudouridine synthase activity
BVV16_RS22075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BVV16_RS22110	COG3039	Transposase
BVV16_RS22130	COG2826	transposase and inactivated derivatives, IS30 family
BVV16_RS22195	COG1074	ATP-dependent DNA helicase activity
BVV16_RS22200	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BVV16_RS22215	COG3039	Transposase
BVV16_RS22220	COG3039	Transposase
BVV16_RS22230	COG1136	(ABC) transporter
BVV16_RS22250	COG1127	ABC transporter
BVV16_RS22255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BVV16_RS22260	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BVV16_RS22275	COG2853	Lipoprotein
BVV16_RS22290	COG0386	Belongs to the glutathione peroxidase family
BVV16_RS22300	COG1322	Protein conserved in bacteria
BVV16_RS22305	COG3039	Transposase
BVV16_RS22330	COG1929	Belongs to the glycerate kinase type-1 family
BVV16_RS22335	COG2271	Major facilitator Superfamily
BVV16_RS22350	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BVV16_RS22360	COG0861	Integral membrane protein TerC family
BVV16_RS22375	COG0584	glycerophosphoryl diester phosphodiesterase
BVV16_RS22385	COG0671	phosphoesterase, PA-phosphatase related
BVV16_RS22390	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BVV16_RS22395	COG0726	polysaccharide deacetylase