locus-tag	class	description
BRN51_RS00025	COG0187	DNA topoisomerase II activity
BRN51_RS00035	COG0501	Belongs to the peptidase M48B family
BRN51_RS00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BRN51_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BRN51_RS00085	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BRN51_RS00095	COG4772	TonB-dependent receptor
BRN51_RS00110	COG3039	Transposase
BRN51_RS00115	COG1304	FMN binding
BRN51_RS00135	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BRN51_RS00145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BRN51_RS00245	COG2826	transposase and inactivated derivatives, IS30 family
BRN51_RS00270	COG3039	Transposase
BRN51_RS00280	COG1090	epimerase
BRN51_RS00290	COG0642	Histidine kinase
BRN51_RS00300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BRN51_RS00405	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BRN51_RS00485	COG1511	domain protein
BRN51_RS00485	COG3264	Mechanosensitive ion channel
BRN51_RS00500	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BRN51_RS00510	COG2354	Protein conserved in bacteria
BRN51_RS00515	COG1649	PFAM Uncharacterised BCR, COG1649
BRN51_RS00525	COG0297	glycogen (starch) synthase activity
BRN51_RS00535	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BRN51_RS00560	COG0702	epimerase
BRN51_RS00570	COG1858	cytochrome C peroxidase
BRN51_RS00650	COG0513	Belongs to the DEAD box helicase family
BRN51_RS00660	COG3039	Transposase
BRN51_RS00710	COG1136	(ABC) transporter
BRN51_RS00735	COG1136	(ABC) transporter
BRN51_RS00780	COG1272	protein, Hemolysin III
BRN51_RS00785	COG1205	dead DEAH box helicase
BRN51_RS00785	COG1111	helicase
BRN51_RS00850	COG0067	glutamate synthase
BRN51_RS00850	COG0070	glutamate synthase
BRN51_RS00850	COG0069	glutamate synthase activity
BRN51_RS00855	COG0493	'glutamate synthase
BRN51_RS00910	COG1609	Transcriptional regulator
BRN51_RS00945	COG0366	Alpha amylase catalytic
BRN51_RS00950	COG0366	Alpha amylase catalytic
BRN51_RS01020	COG0606	chelatase, subunit chli
BRN51_RS01070	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BRN51_RS01075	COG1166	arginine decarboxylase activity
BRN51_RS01145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BRN51_RS01170	COG1028	Short-chain dehydrogenase reductase Sdr
BRN51_RS01195	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BRN51_RS01210	COG0210	DNA helicase
BRN51_RS01225	COG3132	Protein of unknown function, DUF480
BRN51_RS01230	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BRN51_RS01235	COG0284	orotidine-5'-phosphate decarboxylase activity
BRN51_RS01270	COG2937	Belongs to the GPAT DAPAT family
BRN51_RS01320	COG1752	Esterase of the alpha-beta hydrolase superfamily
BRN51_RS01330	COG1119	ATPase activity
BRN51_RS01345	COG0517	IMP dehydrogenase activity
BRN51_RS01345	COG1125	glycine betaine transport
BRN51_RS01360	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BRN51_RS01365	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BRN51_RS01370	COG3550	peptidyl-serine autophosphorylation
BRN51_RS01375	COG1396	sequence-specific DNA binding
BRN51_RS01395	COG0489	protein tyrosine kinase activity
BRN51_RS01400	COG2062	phosphohistidine phosphatase, SixA
BRN51_RS01410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BRN51_RS01455	COG1968	undecaprenyl-diphosphatase activity
BRN51_RS01460	COG0174	glutamine synthetase
BRN51_RS01465	COG0347	Belongs to the P(II) protein family
BRN51_RS01470	COG0004	ammonium transporteR
BRN51_RS01475	COG3852	Histidine kinase
BRN51_RS01480	COG2204	response regulator
BRN51_RS01485	COG2032	superoxide dismutase activity
BRN51_RS01490	COG2032	superoxide dismutase activity
BRN51_RS01525	COG1196	nuclear chromosome segregation
BRN51_RS01530	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BRN51_RS01535	COG1074	ATP-dependent DNA helicase activity
BRN51_RS01545	COG3549	Plasmid maintenance system killer
BRN51_RS01645	COG1764	response to oxidative stress
BRN51_RS01650	COG1846	Transcriptional regulator
BRN51_RS01695	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BRN51_RS01735	COG2211	Major facilitator Superfamily
BRN51_RS01760	COG3693	PFAM glycoside hydrolase, family 10
BRN51_RS01785	COG0246	Mannitol dehydrogenase
BRN51_RS01790	COG1472	Belongs to the glycosyl hydrolase 3 family
BRN51_RS01800	COG4948	Mandelate Racemase Muconate Lactonizing
BRN51_RS01810	COG3661	Belongs to the glycosyl hydrolase 67 family
BRN51_RS01830	COG0037	tRNA processing
BRN51_RS01835	COG2974	May be involved in recombination
BRN51_RS01865	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BRN51_RS01875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BRN51_RS01885	COG0805	protein transport
BRN51_RS01895	COG0519	Catalyzes the synthesis of GMP from XMP
BRN51_RS01895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BRN51_RS01920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BRN51_RS01925	COG0752	glycyl-tRNA synthetase alpha subunit
BRN51_RS01935	COG0457	Tetratricopeptide repeat
BRN51_RS01940	COG4771	TonB-dependent receptor
BRN51_RS01955	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BRN51_RS01975	COG0523	cobalamin synthesis protein
BRN51_RS02030	COG1960	acyl-CoA dehydrogenase activity
BRN51_RS02035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BRN51_RS02040	COG4770	biotin carboxylase activity
BRN51_RS02105	COG2072	flavoprotein involved in K transport
BRN51_RS02125	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BRN51_RS02175	COG0084	hydrolase, TatD family'
BRN51_RS02190	COG0583	DNA-binding transcription factor activity
BRN51_RS02195	COG2814	Major facilitator Superfamily
BRN51_RS02205	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BRN51_RS02210	COG1902	pentaerythritol trinitrate reductase activity
BRN51_RS02240	COG0745	RESPONSE REGULATOR receiver
BRN51_RS02260	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BRN51_RS02265	COG0583	DNA-binding transcription factor activity
BRN51_RS02300	COG0702	epimerase
BRN51_RS02305	COG1733	regulation of RNA biosynthetic process
BRN51_RS02365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BRN51_RS02380	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BRN51_RS02415	COG2911	Protein conserved in bacteria
BRN51_RS02420	COG0729	surface antigen
BRN51_RS02435	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BRN51_RS02440	COG3118	belongs to the thioredoxin family
BRN51_RS02450	COG2884	Cell division ATP-binding protein ftsE
BRN51_RS02455	COG2177	Part of the ABC transporter FtsEX involved in
BRN51_RS02460	COG3437	response regulator, receiver
BRN51_RS02465	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BRN51_RS02470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BRN51_RS02480	COG1252	NADH dehydrogenase
BRN51_RS02505	COG0459	protein refolding
BRN51_RS02515	COG4771	TonB-dependent receptor
BRN51_RS02530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BRN51_RS02570	COG3386	PFAM SMP-30 Gluconolaconase
BRN51_RS02585	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BRN51_RS02620	COG0778	Nitroreductase
BRN51_RS02625	COG2353	YceI-like domain
BRN51_RS02725	COG0408	coproporphyrinogen oxidase activity
BRN51_RS02735	COG3039	Transposase
BRN51_RS02760	COG0129	dihydroxy-acid dehydratase activity
BRN51_RS02770	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BRN51_RS02810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRN51_RS02815	COG0318	PFAM AMP-dependent synthetase and ligase
BRN51_RS02820	COG0727	PFAM Uncharacterised protein family (UPF0153)
BRN51_RS02825	COG0596	Alpha beta hydrolase
BRN51_RS02840	COG3177	Filamentation induced by cAMP protein fic
BRN51_RS02845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BRN51_RS02860	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BRN51_RS02885	COG4191	Histidine kinase
BRN51_RS02890	COG0028	Belongs to the TPP enzyme family
BRN51_RS02905	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BRN51_RS02910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BRN51_RS02955	COG5383	Protein conserved in bacteria
BRN51_RS02970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BRN51_RS02975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRN51_RS02985	COG1473	amidohydrolase
BRN51_RS02995	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BRN51_RS02995	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BRN51_RS03075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BRN51_RS03080	COG0134	indole-3-glycerol-phosphate synthase activity
BRN51_RS03095	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BRN51_RS03110	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BRN51_RS03115	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BRN51_RS03120	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BRN51_RS03170	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BRN51_RS03185	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BRN51_RS03250	COG3039	Transposase
BRN51_RS03275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BRN51_RS03305	COG0534	Mate efflux family protein
BRN51_RS03310	COG0616	signal peptide processing
BRN51_RS03320	COG1028	Short-chain dehydrogenase reductase Sdr
BRN51_RS03335	COG0009	L-threonylcarbamoyladenylate synthase
BRN51_RS03340	COG1754	DNA topoisomerase type I activity
BRN51_RS03340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BRN51_RS03355	COG2922	Belongs to the Smg family
BRN51_RS03360	COG0758	DNA mediated transformation
BRN51_RS03365	COG1652	LysM domain
BRN51_RS03370	COG0242	peptide deformylase activity
BRN51_RS03375	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BRN51_RS03380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BRN51_RS03380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BRN51_RS03430	COG1560	Kdo2-lipid A biosynthetic process
BRN51_RS03440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BRN51_RS03585	COG0358	DNA primase activity
BRN51_RS03590	COG1295	ribonuclease BN
BRN51_RS03610	COG1610	YqeY-like protein
BRN51_RS03620	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BRN51_RS03625	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BRN51_RS03665	COG2133	pyrroloquinoline quinone binding
BRN51_RS03670	COG4682	membrane
BRN51_RS03700	COG0531	amino acid
BRN51_RS03735	COG4948	Mandelate Racemase Muconate Lactonizing
BRN51_RS03745	COG3023	N-Acetylmuramoyl-L-alanine amidase
BRN51_RS03750	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BRN51_RS03825	COG0183	Belongs to the thiolase family
BRN51_RS03860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BRN51_RS03870	COG3483	tryptophan 2,3-dioxygenase activity
BRN51_RS03875	COG3104	oligopeptide transport
BRN51_RS03895	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BRN51_RS03905	COG1320	monovalent cation:proton antiporter activity
BRN51_RS03910	COG2212	antiporter activity
BRN51_RS03920	COG0651	ATP synthesis coupled electron transport
BRN51_RS03925	COG1006	Multisubunit Na H antiporter MnhC subunit
BRN51_RS03930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BRN51_RS03930	COG2111	Na H antiporter
BRN51_RS03975	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BRN51_RS03985	COG0456	acetyltransferase
BRN51_RS04015	COG4221	oxidoreductase activity
BRN51_RS04075	COG0697	spore germination
BRN51_RS04080	COG4305	rare lipoprotein A
BRN51_RS04085	COG5297	Belongs to the glycosyl hydrolase family 6
BRN51_RS04095	COG1113	amino acid transport
BRN51_RS04105	COG0598	Magnesium transport protein CorA
BRN51_RS04125	COG3039	Transposase
BRN51_RS04190	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BRN51_RS04190	COG5297	Belongs to the glycosyl hydrolase family 6
BRN51_RS04195	COG0659	secondary active sulfate transmembrane transporter activity
BRN51_RS04250	COG3275	phosphorelay sensor kinase activity
BRN51_RS04260	COG0181	hydroxymethylbilane synthase activity
BRN51_RS04285	COG1505	serine-type exopeptidase activity
BRN51_RS04300	COG0436	Aminotransferase
BRN51_RS04330	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BRN51_RS04365	COG0308	aminopeptidase N
BRN51_RS04370	COG2199	diguanylate cyclase activity
BRN51_RS04415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BRN51_RS04420	COG1077	Cell shape determining protein MreB Mrl
BRN51_RS04425	COG1792	Involved in formation and maintenance of cell shape
BRN51_RS04440	COG0772	Belongs to the SEDS family
BRN51_RS04480	COG1388	LysM domain
BRN51_RS04480	COG5632	N-Acetylmuramoyl-L-alanine amidase
BRN51_RS04480	COG3409	Peptidoglycan-binding domain 1 protein
BRN51_RS04495	COG2951	lytic endotransglycosylase activity
BRN51_RS04500	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BRN51_RS04510	COG1686	Belongs to the peptidase S11 family
BRN51_RS04525	COG2921	Belongs to the UPF0250 family
BRN51_RS04550	COG1051	belongs to the nudix hydrolase family
BRN51_RS04550	COG1056	cytidyltransferase-related domain
BRN51_RS04585	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BRN51_RS04590	COG0673	inositol 2-dehydrogenase activity
BRN51_RS04595	COG2823	Periplasmic or secreted lipoprotein
BRN51_RS04600	COG4251	negative regulation of phosphorylation
BRN51_RS04605	COG0784	Response regulator, receiver
BRN51_RS04610	COG4191	Histidine kinase
BRN51_RS04615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BRN51_RS04665	COG3250	beta-galactosidase activity
BRN51_RS04680	COG2188	Transcriptional regulator
BRN51_RS04690	COG1609	Transcriptional regulator
BRN51_RS04695	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BRN51_RS04700	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BRN51_RS04710	COG1215	transferase activity, transferring glycosyl groups
BRN51_RS04715	COG1649	PFAM Uncharacterised BCR, COG1649
BRN51_RS04715	COG0726	polysaccharide deacetylase
BRN51_RS04850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BRN51_RS04865	COG3039	Transposase
BRN51_RS04900	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BRN51_RS04945	COG2205	protein histidine kinase activity
BRN51_RS05000	COG0488	(ABC) transporter
BRN51_RS05020	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BRN51_RS05040	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BRN51_RS05040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BRN51_RS05060	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BRN51_RS05065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BRN51_RS05070	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BRN51_RS05095	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BRN51_RS05100	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BRN51_RS05110	COG2205	protein histidine kinase activity
BRN51_RS05115	COG0745	RESPONSE REGULATOR receiver
BRN51_RS05120	COG0277	FAD linked oxidase domain protein
BRN51_RS05125	COG1988	membrane-bound metal-dependent
BRN51_RS05130	COG0792	nuclease activity
BRN51_RS05165	COG0275	rRNA processing
BRN51_RS05170	COG3116	cell division
BRN51_RS05185	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BRN51_RS05190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BRN51_RS05205	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BRN51_RS05210	COG1181	Belongs to the D-alanine--D-alanine ligase family
BRN51_RS05215	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BRN51_RS05230	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BRN51_RS05240	COG4942	peptidase
BRN51_RS05240	COG1388	LysM domain
BRN51_RS05245	COG0653	protein targeting
BRN51_RS05255	COG0494	nUDIX hydrolase
BRN51_RS05270	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BRN51_RS05285	COG1028	Short-chain dehydrogenase reductase Sdr
BRN51_RS05285	COG3321	synthase
BRN51_RS05285	COG0604	alcohol dehydrogenase
BRN51_RS05340	COG2226	methyltransferase
BRN51_RS05345	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BRN51_RS05400	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BRN51_RS05415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BRN51_RS05435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BRN51_RS05440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BRN51_RS05450	COG3039	Transposase
BRN51_RS05460	COG0667	Aldo Keto reductase
BRN51_RS05510	COG2175	clavaminate synthase activity
BRN51_RS05520	COG4181	ATPase activity
BRN51_RS05535	COG0642	Histidine kinase
BRN51_RS05555	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BRN51_RS05575	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BRN51_RS05595	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BRN51_RS05600	COG2967	ApaG domain
BRN51_RS05605	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BRN51_RS05615	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BRN51_RS05630	COG0123	including yeast histone deacetylase and acetoin utilization protein
BRN51_RS05635	COG2096	Adenosyltransferase
BRN51_RS05645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BRN51_RS05650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BRN51_RS05690	COG0583	DNA-binding transcription factor activity
BRN51_RS05695	COG0318	PFAM AMP-dependent synthetase and ligase
BRN51_RS05705	COG1024	Enoyl-CoA hydratase
BRN51_RS05725	COG3386	PFAM SMP-30 Gluconolaconase
BRN51_RS05735	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BRN51_RS05825	COG3039	Transposase
BRN51_RS05840	COG3039	Transposase
BRN51_RS05870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BRN51_RS05900	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BRN51_RS05905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BRN51_RS05915	COG0583	DNA-binding transcription factor activity
BRN51_RS05920	COG3634	alkyl hydroperoxide reductase activity
BRN51_RS05930	COG2890	protein-(glutamine-N5) methyltransferase activity
BRN51_RS05970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BRN51_RS05970	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BRN51_RS05985	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BRN51_RS06010	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BRN51_RS06040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BRN51_RS06055	COG1404	Belongs to the peptidase S8 family
BRN51_RS06060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BRN51_RS06090	COG1295	ribonuclease BN
BRN51_RS06095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRN51_RS06115	COG0521	Mo-molybdopterin cofactor biosynthetic process
BRN51_RS06125	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BRN51_RS06130	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BRN51_RS06140	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BRN51_RS06155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BRN51_RS06165	COG0193	aminoacyl-tRNA hydrolase activity
BRN51_RS06170	COG0012	GTP binding
BRN51_RS06200	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BRN51_RS06205	COG0250	Participates in transcription elongation, termination and antitermination
BRN51_RS06215	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BRN51_RS06220	COG0081	regulation of translation
BRN51_RS06225	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BRN51_RS06230	COG0222	ribosome binding
BRN51_RS06235	COG0085	RNA polymerase activity
BRN51_RS06240	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BRN51_RS06245	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BRN51_RS06250	COG0049	tRNA binding
BRN51_RS06270	COG0051	transcription antitermination factor activity, RNA binding
BRN51_RS06275	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BRN51_RS06280	COG0088	Forms part of the polypeptide exit tunnel
BRN51_RS06285	COG0089	rRNA binding
BRN51_RS06300	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BRN51_RS06310	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BRN51_RS06315	COG0255	Belongs to the universal ribosomal protein uL29 family
BRN51_RS06320	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BRN51_RS06325	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BRN51_RS06330	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BRN51_RS06335	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BRN51_RS06355	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BRN51_RS06365	COG1841	ribosomal large subunit assembly
BRN51_RS06375	COG0201	protein transport
BRN51_RS06385	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BRN51_RS06390	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BRN51_RS06400	COG0203	ribosomal protein L17
BRN51_RS06465	COG3551	Protein conserved in bacteria
BRN51_RS06495	COG2194	sulfuric ester hydrolase activity
BRN51_RS06505	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BRN51_RS06510	COG0745	RESPONSE REGULATOR receiver
BRN51_RS06515	COG0642	Histidine kinase
BRN51_RS06525	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BRN51_RS06530	COG2894	cell division
BRN51_RS06550	COG4585	Histidine kinase
BRN51_RS06555	COG2197	response regulator
BRN51_RS06570	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BRN51_RS06595	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BRN51_RS06600	COG2963	transposase activity
BRN51_RS06660	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BRN51_RS06670	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BRN51_RS06705	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BRN51_RS06740	COG3039	Transposase
BRN51_RS06760	COG3039	Transposase
BRN51_RS06780	COG3039	Transposase
BRN51_RS06805	COG1741	Belongs to the pirin family
BRN51_RS06815	COG1515	deoxyribonuclease V activity
BRN51_RS06820	COG0588	phosphoglycerate mutase activity
BRN51_RS06840	COG3590	peptidase
BRN51_RS06855	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BRN51_RS06860	COG2202	Pas domain
BRN51_RS06860	COG2200	EAL domain
BRN51_RS06860	COG2199	diguanylate cyclase activity
BRN51_RS06865	COG0835	chemotaxis
BRN51_RS06870	COG0840	transmembrane signaling receptor activity
BRN51_RS06885	COG3039	Transposase
BRN51_RS06900	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BRN51_RS06910	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BRN51_RS06925	COG2205	protein histidine kinase activity
BRN51_RS06955	COG3039	Transposase
BRN51_RS07005	COG3039	Transposase
BRN51_RS07030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BRN51_RS07035	COG0735	belongs to the Fur family
BRN51_RS07095	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BRN51_RS07100	COG0084	hydrolase, TatD family'
BRN51_RS07115	COG1960	acyl-CoA dehydrogenase activity
BRN51_RS07130	COG0367	asparagine synthase
BRN51_RS07140	COG0305	Participates in initiation and elongation during chromosome replication
BRN51_RS07145	COG0415	Belongs to the DNA photolyase family
BRN51_RS07165	COG1028	Short-chain dehydrogenase reductase Sdr
BRN51_RS07265	COG5002	protein histidine kinase activity
BRN51_RS07265	COG5001	Diguanylate cyclase
BRN51_RS07270	COG1187	pseudouridine synthase activity
BRN51_RS07295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BRN51_RS07305	COG0475	glutathione-regulated potassium exporter activity
BRN51_RS07310	COG5002	protein histidine kinase activity
BRN51_RS07310	COG5000	phosphorelay sensor kinase activity
BRN51_RS07315	COG0745	RESPONSE REGULATOR receiver
BRN51_RS07345	COG1132	(ABC) transporter
BRN51_RS07385	COG3209	COG3209 Rhs family protein
BRN51_RS07395	COG3039	Transposase
BRN51_RS07435	COG3039	Transposase
BRN51_RS07445	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BRN51_RS07455	COG4969	Belongs to the N-Me-Phe pilin family
BRN51_RS07460	COG2194	sulfuric ester hydrolase activity
BRN51_RS07480	COG2184	nucleotidyltransferase activity
BRN51_RS07500	COG0045	succinate-CoA ligase (ADP-forming) activity
BRN51_RS07505	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BRN51_RS07515	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BRN51_RS07515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BRN51_RS07520	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BRN51_RS07525	COG0564	pseudouridine synthase activity
BRN51_RS07550	COG3387	PFAM Glycoside hydrolase 15-related
BRN51_RS07555	COG1877	trehalose-phosphatase activity
BRN51_RS07595	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BRN51_RS07610	COG1595	DNA-templated transcription, initiation
BRN51_RS07620	COG1946	Acyl-CoA thioesterase
BRN51_RS07635	COG0824	Thioesterase
BRN51_RS07640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BRN51_RS07650	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BRN51_RS07655	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BRN51_RS07660	COG0268	Binds directly to 16S ribosomal RNA
BRN51_RS07665	COG0728	peptidoglycan biosynthetic process
BRN51_RS07670	COG0196	riboflavin kinase activity
BRN51_RS07680	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BRN51_RS07685	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BRN51_RS07700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BRN51_RS07705	COG1845	cytochrome c oxidase, subunit III
BRN51_RS07710	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BRN51_RS07795	COG3039	Transposase
BRN51_RS07830	COG3039	Transposase
BRN51_RS07895	COG3039	Transposase
BRN51_RS07995	COG0631	protein serine/threonine phosphatase activity
BRN51_RS08000	COG0515	serine threonine protein kinase
BRN51_RS08030	COG1858	cytochrome C peroxidase
BRN51_RS08095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRN51_RS08100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BRN51_RS08120	COG2201	protein-glutamate methylesterase activity
BRN51_RS08165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRN51_RS08185	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BRN51_RS08200	COG1595	DNA-templated transcription, initiation
BRN51_RS08250	COG2244	polysaccharide biosynthetic process
BRN51_RS08280	COG2264	protein methyltransferase activity
BRN51_RS08290	COG0438	transferase activity, transferring glycosyl groups
BRN51_RS08305	COG1136	(ABC) transporter
BRN51_RS08310	COG1132	(ABC) transporter
BRN51_RS08320	COG0477	Major facilitator Superfamily
BRN51_RS08340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BRN51_RS08355	COG1253	flavin adenine dinucleotide binding
BRN51_RS08370	COG0306	phosphate transporter
BRN51_RS08400	COG0504	CTP synthase activity
BRN51_RS08405	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BRN51_RS08415	COG0148	phosphopyruvate hydratase activity
BRN51_RS08420	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BRN51_RS08425	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BRN51_RS08435	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BRN51_RS08445	COG2840	Smr protein MutS2
BRN51_RS08450	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BRN51_RS08455	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BRN51_RS08460	COG1238	metal cluster binding
BRN51_RS08475	COG1534	Rna-binding protein
BRN51_RS08480	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BRN51_RS08490	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BRN51_RS08495	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BRN51_RS08505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BRN51_RS08510	COG1546	Belongs to the CinA family
BRN51_RS08525	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BRN51_RS08535	COG2137	regulation of response to DNA damage stimulus
BRN51_RS08540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BRN51_RS08545	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BRN51_RS08565	COG0305	Participates in initiation and elongation during chromosome replication
BRN51_RS08570	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BRN51_RS08595	COG1741	Belongs to the pirin family
BRN51_RS08600	COG0583	DNA-binding transcription factor activity
BRN51_RS08630	COG0351	phosphomethylpyrimidine kinase
BRN51_RS08640	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BRN51_RS08645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BRN51_RS08660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BRN51_RS08670	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BRN51_RS08675	COG3734	2-keto-3-deoxy-galactonokinase
BRN51_RS08685	COG4948	Mandelate Racemase Muconate Lactonizing
BRN51_RS08690	COG0800	Aldolase
BRN51_RS08705	COG1501	Belongs to the glycosyl hydrolase 31 family
BRN51_RS08715	COG1070	Carbohydrate kinase
BRN51_RS08725	COG0477	Major facilitator Superfamily
BRN51_RS08745	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BRN51_RS08795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRN51_RS08800	COG2258	MOSC domain
BRN51_RS08810	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BRN51_RS08815	COG0505	Belongs to the CarA family
BRN51_RS08825	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BRN51_RS08830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BRN51_RS08840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BRN51_RS08900	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BRN51_RS08915	COG0784	Response regulator, receiver
BRN51_RS08915	COG2205	protein histidine kinase activity
BRN51_RS08915	COG2198	Histidine kinase
BRN51_RS08920	COG1024	Enoyl-CoA hydratase
BRN51_RS08925	COG0318	PFAM AMP-dependent synthetase and ligase
BRN51_RS08955	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BRN51_RS08990	COG0840	transmembrane signaling receptor activity
BRN51_RS09015	COG0835	chemotaxis
BRN51_RS09040	COG0840	transmembrane signaling receptor activity
BRN51_RS09045	COG0840	transmembrane signaling receptor activity
BRN51_RS09050	COG0840	transmembrane signaling receptor activity
BRN51_RS09055	COG0840	transmembrane signaling receptor activity
BRN51_RS09065	COG0840	transmembrane signaling receptor activity
BRN51_RS09075	COG0840	transmembrane signaling receptor activity
BRN51_RS09090	COG0840	transmembrane signaling receptor activity
BRN51_RS09115	COG0745	RESPONSE REGULATOR receiver
BRN51_RS09125	COG0835	chemotaxis
BRN51_RS09135	COG1360	Flagellar Motor Protein
BRN51_RS09140	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BRN51_RS09160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BRN51_RS09170	COG4771	TonB-dependent receptor
BRN51_RS09300	COG3039	Transposase
BRN51_RS09310	COG3039	Transposase
BRN51_RS09325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BRN51_RS09325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BRN51_RS09330	COG1105	Belongs to the carbohydrate kinase PfkB family
BRN51_RS09335	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRN51_RS09335	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BRN51_RS09340	COG1609	Transcriptional regulator
BRN51_RS09365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BRN51_RS09370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRN51_RS09380	COG2902	Dehydrogenase
BRN51_RS09390	COG3039	Transposase
BRN51_RS09400	COG2205	protein histidine kinase activity
BRN51_RS09400	COG0784	Response regulator, receiver
BRN51_RS09400	COG5002	protein histidine kinase activity
BRN51_RS09405	COG2733	membrane
BRN51_RS09415	COG1121	(ABC) transporter
BRN51_RS09420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BRN51_RS09430	COG2223	nitrite transmembrane transporter activity
BRN51_RS09440	COG0243	molybdopterin cofactor binding
BRN51_RS09450	COG0477	Major facilitator Superfamily
BRN51_RS09460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRN51_RS09465	COG0174	glutamine synthetase
BRN51_RS09510	COG3842	ATPase activity
BRN51_RS09520	COG1177	transmembrane transport
BRN51_RS09530	COG1012	belongs to the aldehyde dehydrogenase family
BRN51_RS09545	COG4535	Mg2 and Co2 transporter CorC
BRN51_RS09565	COG1702	phosphate starvation-inducible protein PhoH
BRN51_RS09570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BRN51_RS09590	COG0741	lytic transglycosylase activity
BRN51_RS09600	COG0723	plastoquinol--plastocyanin reductase activity
BRN51_RS09605	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BRN51_RS09610	COG2857	Cytochrome c1
BRN51_RS09615	COG0625	glutathione transferase activity
BRN51_RS09620	COG2969	positive regulation of protein catabolic process
BRN51_RS09665	COG3328	transposase activity
BRN51_RS09755	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BRN51_RS09770	COG1570	exodeoxyribonuclease VII activity
BRN51_RS09775	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BRN51_RS09780	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BRN51_RS09780	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BRN51_RS09785	COG0802	atpase or kinase
BRN51_RS09790	COG0860	N-Acetylmuramoyl-L-alanine amidase
BRN51_RS09795	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BRN51_RS09820	COG1028	Short-chain dehydrogenase reductase Sdr
BRN51_RS09830	COG0501	Belongs to the peptidase M48B family
BRN51_RS09840	COG2081	HI0933 family
BRN51_RS09845	COG4681	YaeQ
BRN51_RS09850	COG1671	Belongs to the UPF0178 family
BRN51_RS09860	COG0625	glutathione transferase activity
BRN51_RS09870	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BRN51_RS09875	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BRN51_RS09880	COG0513	Belongs to the DEAD box helicase family
BRN51_RS09885	COG0488	(ABC) transporter
BRN51_RS09910	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BRN51_RS09915	COG0483	inositol monophosphate 1-phosphatase activity
BRN51_RS09930	COG5001	Diguanylate cyclase
BRN51_RS09930	COG3300	MHYT domain
BRN51_RS09935	COG1509	lysine 2,3-aminomutase activity
BRN51_RS09950	COG0402	S-adenosylhomocysteine deaminase activity
BRN51_RS09955	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BRN51_RS09985	COG4677	pectinesterase activity
BRN51_RS10010	COG3039	Transposase
BRN51_RS10045	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BRN51_RS10070	COG2166	iron-sulfur cluster assembly
BRN51_RS10085	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BRN51_RS10090	COG0137	argininosuccinate synthase activity
BRN51_RS10100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BRN51_RS10105	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BRN51_RS10120	COG0165	Argininosuccinate lyase
BRN51_RS10140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BRN51_RS10170	COG1271	oxidase subunit
BRN51_RS10180	COG4988	ABC transporter
BRN51_RS10185	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BRN51_RS10310	COG0742	ribosomal rna small subunit methyltransferase
BRN51_RS10315	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BRN51_RS10330	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BRN51_RS10335	COG0405	Gamma-glutamyltransferase
BRN51_RS10405	COG3039	Transposase
BRN51_RS10445	COG0343	queuine tRNA-ribosyltransferase activity
BRN51_RS10450	COG1862	Preprotein translocase
BRN51_RS10455	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BRN51_RS10460	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BRN51_RS10490	COG3328	transposase activity
BRN51_RS10510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BRN51_RS10520	COG0704	Plays a role in the regulation of phosphate uptake
BRN51_RS10535	COG0573	inorganic phosphate transmembrane transporter activity
BRN51_RS10540	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BRN51_RS10575	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BRN51_RS10585	COG1024	Enoyl-CoA hydratase
BRN51_RS10595	COG0494	nUDIX hydrolase
BRN51_RS10640	COG0116	Belongs to the methyltransferase superfamily
BRN51_RS10640	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BRN51_RS10665	COG0667	Aldo Keto reductase
BRN51_RS10675	COG2925	Exonuclease
BRN51_RS10685	COG3844	kynureninase activity
BRN51_RS10705	COG0288	reversible hydration of carbon dioxide
BRN51_RS10740	COG0316	Belongs to the HesB IscA family
BRN51_RS10745	COG0360	Binds together with S18 to 16S ribosomal RNA
BRN51_RS10755	COG0359	binds to the 23S rRNA
BRN51_RS10765	COG3115	cell septum assembly
BRN51_RS10780	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BRN51_RS10795	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BRN51_RS10820	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BRN51_RS10830	COG2986	histidine ammonia-lyase
BRN51_RS10835	COG1228	amidohydrolase
BRN51_RS10880	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BRN51_RS10885	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BRN51_RS10890	COG1605	Chorismate mutase
BRN51_RS10890	COG0077	Prephenate dehydratase
BRN51_RS10895	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BRN51_RS10925	COG4566	intracellular signal transduction
BRN51_RS10980	COG0860	N-Acetylmuramoyl-L-alanine amidase
BRN51_RS10985	COG1469	GTP cyclohydrolase I activity
BRN51_RS10995	COG0617	tRNA 3'-terminal CCA addition
BRN51_RS11005	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BRN51_RS11010	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BRN51_RS11020	COG0166	Belongs to the GPI family
BRN51_RS11045	COG1472	Belongs to the glycosyl hydrolase 3 family
BRN51_RS11065	COG5001	Diguanylate cyclase
BRN51_RS11065	COG4251	negative regulation of phosphorylation
BRN51_RS11065	COG2203	Gaf domain
BRN51_RS11065	COG3706	GGDEF domain
BRN51_RS11155	COG0386	Belongs to the glutathione peroxidase family
BRN51_RS11230	COG1247	-acetyltransferase
BRN51_RS11250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BRN51_RS11280	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BRN51_RS11295	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BRN51_RS11300	COG1393	Belongs to the ArsC family
BRN51_RS11305	COG0431	NADPH-dependent FMN reductase
BRN51_RS11310	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BRN51_RS11315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BRN51_RS11340	COG5002	protein histidine kinase activity
BRN51_RS11340	COG0784	Response regulator, receiver
BRN51_RS11340	COG2205	protein histidine kinase activity
BRN51_RS11375	COG0800	Aldolase
BRN51_RS11380	COG0129	dihydroxy-acid dehydratase activity
BRN51_RS11385	COG0363	glucosamine-6-phosphate deaminase activity
BRN51_RS11395	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BRN51_RS11410	COG0354	folic acid binding
BRN51_RS11425	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BRN51_RS11440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BRN51_RS11455	COG4591	ABC-type transport system involved in lipoprotein release permease component
BRN51_RS11485	COG0811	peptide transport
BRN51_RS11500	COG1663	tetraacyldisaccharide 4'-kinase activity
BRN51_RS11510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BRN51_RS11520	COG0322	excinuclease ABC activity
BRN51_RS11555	COG3328	transposase activity
BRN51_RS11575	COG2801	Transposase and inactivated derivatives
BRN51_RS11585	COG2201	protein-glutamate methylesterase activity
BRN51_RS11620	COG0653	protein targeting
BRN51_RS11780	COG0140	phosphoribosyl-ATP diphosphatase activity
BRN51_RS11780	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BRN51_RS11790	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BRN51_RS11800	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BRN51_RS11800	COG0131	Imidazoleglycerol-phosphate dehydratase
BRN51_RS11815	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BRN51_RS11845	COG0124	histidyl-tRNA synthetase
BRN51_RS11860	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BRN51_RS11905	COG1012	belongs to the aldehyde dehydrogenase family
BRN51_RS11920	COG0167	dihydroorotate dehydrogenase activity
BRN51_RS11925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BRN51_RS11930	COG0697	spore germination
BRN51_RS11940	COG1794	racemase activity, acting on amino acids and derivatives
BRN51_RS11965	COG0671	phosphoesterase, PA-phosphatase related
BRN51_RS11980	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BRN51_RS11995	COG2183	response to ionizing radiation
BRN51_RS12005	COG0723	plastoquinol--plastocyanin reductase activity
BRN51_RS12005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRN51_RS12020	COG3243	poly(R)-hydroxyalkanoic acid synthase
BRN51_RS12030	COG1183	phosphatidylcholine synthase activity
BRN51_RS12035	COG1028	Short-chain dehydrogenase reductase Sdr
BRN51_RS12050	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BRN51_RS12060	COG0668	transmembrane transport
BRN51_RS12080	COG1914	H( )-stimulated, divalent metal cation uptake system
BRN51_RS12140	COG0583	DNA-binding transcription factor activity
BRN51_RS12145	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BRN51_RS12150	COG3002	Belongs to the UPF0753 family
BRN51_RS12155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BRN51_RS12155	COG0519	Catalyzes the synthesis of GMP from XMP
BRN51_RS12165	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BRN51_RS12185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BRN51_RS12195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BRN51_RS12200	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BRN51_RS12210	COG0776	regulation of translation
BRN51_RS12215	COG0539	negative regulation of cytoplasmic translation
BRN51_RS12220	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BRN51_RS12235	COG2957	Belongs to the agmatine deiminase family
BRN51_RS12245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BRN51_RS12270	COG0395	ABC-type sugar transport system, permease component
BRN51_RS12275	COG1175	transmembrane transport
BRN51_RS12305	COG2350	Protein conserved in bacteria
BRN51_RS12310	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BRN51_RS12315	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BRN51_RS12320	COG1187	pseudouridine synthase activity
BRN51_RS12345	COG0436	Aminotransferase
BRN51_RS12410	COG0277	FAD linked oxidase domain protein
BRN51_RS12415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BRN51_RS12425	COG0531	amino acid
BRN51_RS12430	COG0531	amino acid
BRN51_RS12435	COG0235	Class ii aldolase
BRN51_RS12440	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BRN51_RS12445	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BRN51_RS12475	COG3039	Transposase
BRN51_RS12485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BRN51_RS12565	COG0303	'Molybdopterin
BRN51_RS12575	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BRN51_RS12585	COG1426	Protein conserved in bacteria
BRN51_RS12595	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BRN51_RS12610	COG1024	Enoyl-CoA hydratase
BRN51_RS12610	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRN51_RS12615	COG0183	Belongs to the thiolase family
BRN51_RS12620	COG0038	chloride channel
BRN51_RS12640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BRN51_RS12665	COG1674	ftsk spoiiie
BRN51_RS12670	COG0492	ferredoxin-NADP+ reductase activity
BRN51_RS12695	COG0542	response to heat
BRN51_RS12710	COG0482	sulfurtransferase activity
BRN51_RS12735	COG5001	Diguanylate cyclase
BRN51_RS12740	COG4585	Histidine kinase
BRN51_RS12750	COG5002	protein histidine kinase activity
BRN51_RS12770	COG0835	chemotaxis
BRN51_RS12770	COG0784	Response regulator, receiver
BRN51_RS12780	COG1558	bacterial-type flagellum-dependent cell motility
BRN51_RS12785	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BRN51_RS12795	COG4787	bacterial-type flagellum-dependent cell motility
BRN51_RS12835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BRN51_RS12840	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BRN51_RS12870	COG2201	protein-glutamate methylesterase activity
BRN51_RS12890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BRN51_RS12900	COG1028	Short-chain dehydrogenase reductase Sdr
BRN51_RS12935	COG1677	Flagellar hook-basal body complex protein FliE
BRN51_RS12985	COG3190	flagellar
BRN51_RS13005	COG1684	flagellar biosynthetic protein fliR
BRN51_RS13060	COG0643	Histidine kinase
BRN51_RS13060	COG2198	Histidine kinase
BRN51_RS13060	COG0784	Response regulator, receiver
BRN51_RS13190	COG0583	DNA-binding transcription factor activity
BRN51_RS13200	COG3039	Transposase
BRN51_RS13295	COG1278	Cold shock
BRN51_RS13305	COG3328	transposase activity
BRN51_RS13345	COG3039	Transposase
BRN51_RS13360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BRN51_RS13375	COG0557	exoribonuclease II activity
BRN51_RS13405	COG1960	acyl-CoA dehydrogenase activity
BRN51_RS13410	COG2226	methyltransferase
BRN51_RS13415	COG0646	methionine synthase
BRN51_RS13415	COG1410	methionine synthase
BRN51_RS13420	COG0646	methionine synthase
BRN51_RS13420	COG1410	methionine synthase
BRN51_RS13430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BRN51_RS13440	COG1609	Transcriptional regulator
BRN51_RS13455	COG2900	Belongs to the SlyX family
BRN51_RS13470	COG0386	Belongs to the glutathione peroxidase family
BRN51_RS13480	COG1725	Transcriptional regulator
BRN51_RS13485	COG1131	(ABC) transporter
BRN51_RS13565	COG2850	peptidyl-arginine hydroxylation
BRN51_RS13600	COG1132	(ABC) transporter
BRN51_RS13615	COG0583	DNA-binding transcription factor activity
BRN51_RS13635	COG0287	Prephenate dehydrogenase
BRN51_RS13635	COG1605	Chorismate mutase
BRN51_RS13640	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BRN51_RS13650	COG0484	heat shock protein binding
BRN51_RS13655	COG0443	Heat shock 70 kDa protein
BRN51_RS13660	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BRN51_RS13670	COG0497	DNA recombination
BRN51_RS13680	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BRN51_RS13690	COG2914	Belongs to the UPF0125 (RnfH) family
BRN51_RS13700	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BRN51_RS13715	COG1960	acyl-CoA dehydrogenase activity
BRN51_RS13725	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BRN51_RS13770	COG2814	Major facilitator Superfamily
BRN51_RS13775	COG1566	PFAM secretion protein HlyD family protein
BRN51_RS13790	COG2207	Transcriptional regulator
BRN51_RS13825	COG4774	siderophore transport
BRN51_RS13840	COG0367	asparagine synthase
BRN51_RS13845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BRN51_RS13855	COG1393	Belongs to the ArsC family
BRN51_RS13915	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BRN51_RS13930	COG0233	cytoplasmic translational termination
BRN51_RS13940	COG0575	Belongs to the CDS family
BRN51_RS13945	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BRN51_RS13950	COG0750	zinc metalloprotease
BRN51_RS13975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BRN51_RS13980	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BRN51_RS14000	COG0825	malonyl-CoA metabolic process
BRN51_RS14010	COG4771	TonB-dependent receptor
BRN51_RS14015	COG1131	(ABC) transporter
BRN51_RS14040	COG1981	membrane
BRN51_RS14085	COG2895	sulfate adenylyltransferase (ATP) activity
BRN51_RS14085	COG0529	Catalyzes the synthesis of activated sulfate
BRN51_RS14125	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BRN51_RS14145	COG2040	homocysteine
BRN51_RS14150	COG0833	amino acid
BRN51_RS14170	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BRN51_RS14170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BRN51_RS14180	COG2878	Part of a membrane complex involved in electron transport
BRN51_RS14200	COG1595	DNA-templated transcription, initiation
BRN51_RS14225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BRN51_RS14240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BRN51_RS14245	COG0251	oxidation-reduction process
BRN51_RS14255	COG0392	lysyltransferase activity
BRN51_RS14255	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BRN51_RS14300	COG2814	Major facilitator Superfamily
BRN51_RS14305	COG1902	pentaerythritol trinitrate reductase activity
BRN51_RS14320	COG2824	Alkylphosphonate utilization operon protein PhnA
BRN51_RS14335	COG1047	Peptidyl-prolyl cis-trans
BRN51_RS14370	COG3039	Transposase
BRN51_RS14375	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BRN51_RS14390	COG1451	nucleotide metabolic process
BRN51_RS14415	COG0183	Belongs to the thiolase family
BRN51_RS14445	COG1793	dna ligase
BRN51_RS14445	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BRN51_RS14455	COG1793	dna ligase
BRN51_RS14460	COG1201	RNA secondary structure unwinding
BRN51_RS14480	COG1278	Cold shock
BRN51_RS14485	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BRN51_RS14490	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BRN51_RS14500	COG3046	protein related to deoxyribodipyrimidine photolyase
BRN51_RS14505	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
BRN51_RS14525	COG2954	triphosphatase activity
BRN51_RS14540	COG1381	Involved in DNA repair and RecF pathway recombination
BRN51_RS14570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BRN51_RS14585	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRN51_RS14585	COG1024	Enoyl-CoA hydratase
BRN51_RS14605	COG1024	Enoyl-CoA hydratase
BRN51_RS14610	COG1960	acyl-CoA dehydrogenase activity
BRN51_RS14675	COG2353	YceI-like domain
BRN51_RS14685	COG2353	YceI-like domain
BRN51_RS14700	COG1760	l-serine dehydratase
BRN51_RS14710	COG0626	cystathionine gamma-synthase activity
BRN51_RS14715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BRN51_RS14720	COG0739	heme binding
BRN51_RS14725	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BRN51_RS14730	COG1272	protein, Hemolysin III
BRN51_RS14755	COG0463	Glycosyl transferase, family 2
BRN51_RS14765	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BRN51_RS14775	COG4771	TonB-dependent receptor
BRN51_RS14780	COG1309	transcriptional regulator
BRN51_RS14790	COG1960	acyl-CoA dehydrogenase activity
BRN51_RS14825	COG0509	glycine decarboxylation via glycine cleavage system
BRN51_RS14830	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BRN51_RS14840	COG0330	HflC and HflK could
BRN51_RS14855	COG3956	TIGRFAM MazG family protein
BRN51_RS14865	COG0494	nUDIX hydrolase
BRN51_RS14875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BRN51_RS14880	COG0837	glucose binding
BRN51_RS14895	COG1388	LysM domain
BRN51_RS14895	COG3858	chitin binding
BRN51_RS14915	COG1472	Belongs to the glycosyl hydrolase 3 family
BRN51_RS14980	COG3537	Alpha-1,2-mannosidase
BRN51_RS15030	COG1446	asparaginase
BRN51_RS15085	COG0784	Response regulator, receiver
BRN51_RS15085	COG0643	Histidine kinase
BRN51_RS15085	COG2198	Histidine kinase
BRN51_RS15090	COG0840	transmembrane signaling receptor activity
BRN51_RS15095	COG0835	chemotaxis
BRN51_RS15110	COG0189	ligase activity
BRN51_RS15120	COG1397	ADP-ribosylglycohydrolase
BRN51_RS15130	COG1199	ATP-dependent helicase activity
BRN51_RS15140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BRN51_RS15145	COG1215	transferase activity, transferring glycosyl groups
BRN51_RS15155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BRN51_RS15170	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BRN51_RS15175	COG0535	radical SAM domain protein
BRN51_RS15180	COG0535	radical SAM domain protein
BRN51_RS15205	COG1643	Atp-dependent helicase
BRN51_RS15210	COG0783	Belongs to the Dps family
BRN51_RS15220	COG0514	ATP-dependent DNA helicase (RecQ)
BRN51_RS15245	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BRN51_RS15270	COG0602	queuosine metabolic process
BRN51_RS15280	COG2885	chlorophyll binding
BRN51_RS15285	COG0823	Involved in the tonB-independent uptake of proteins
BRN51_RS15295	COG0848	biopolymer transport protein
BRN51_RS15305	COG0824	Thioesterase
BRN51_RS15310	COG2255	four-way junction helicase activity
BRN51_RS15320	COG0632	four-way junction helicase activity
BRN51_RS15325	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BRN51_RS15330	COG0217	transcriptional regulatory protein
BRN51_RS15345	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BRN51_RS15360	COG0477	Major facilitator Superfamily
BRN51_RS15470	COG0316	Belongs to the HesB IscA family
BRN51_RS15470	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BRN51_RS15475	COG2154	pterin-4-alpha-carbinolamine dehydratase
BRN51_RS15485	COG0428	transporter
BRN51_RS15490	COG0428	transporter
BRN51_RS15495	COG3064	Membrane
BRN51_RS15505	COG1530	ribonuclease E activity
BRN51_RS15525	COG1054	Belongs to the UPF0176 family
BRN51_RS15545	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BRN51_RS15605	COG3039	Transposase
BRN51_RS15610	COG3039	Transposase
BRN51_RS15655	COG1648	precorrin-2 dehydrogenase activity
BRN51_RS15655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BRN51_RS15680	COG0746	molybdenum cofactor guanylyltransferase activity
BRN51_RS15765	COG4206	TonB-dependent receptor
BRN51_RS15815	COG0531	amino acid
BRN51_RS15830	COG0006	proline dipeptidase activity
BRN51_RS15840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BRN51_RS15855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRN51_RS15860	COG3938	Belongs to the proline racemase family
BRN51_RS15870	COG0552	protein localization to endoplasmic reticulum
BRN51_RS15895	COG0784	Response regulator, receiver
BRN51_RS15895	COG4191	Histidine kinase
BRN51_RS15990	COG3040	lipid binding
BRN51_RS16030	COG0438	transferase activity, transferring glycosyl groups
BRN51_RS16040	COG0438	transferase activity, transferring glycosyl groups
BRN51_RS16045	COG0438	transferase activity, transferring glycosyl groups
BRN51_RS16100	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BRN51_RS16105	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BRN51_RS16115	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BRN51_RS16155	COG0556	nucleotide-excision repair
BRN51_RS16160	COG4969	Belongs to the N-Me-Phe pilin family
BRN51_RS16175	COG3039	Transposase
BRN51_RS16215	COG4695	Portal protein
BRN51_RS16260	COG3179	chitinase
BRN51_RS16475	COG1611	Belongs to the LOG family
BRN51_RS16490	COG2095	MarC family integral membrane protein
BRN51_RS16500	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BRN51_RS16535	COG1185	polyribonucleotide nucleotidyltransferase activity
BRN51_RS16540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BRN51_RS16555	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BRN51_RS16560	COG0195	Participates in both transcription termination and antitermination
BRN51_RS16565	COG0779	Required for maturation of 30S ribosomal subunits
BRN51_RS16575	COG1007	ATP synthesis coupled electron transport
BRN51_RS16605	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BRN51_RS16610	COG1034	ATP synthesis coupled electron transport
BRN51_RS16615	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BRN51_RS16620	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BRN51_RS16625	COG0649	NAD binding
BRN51_RS16630	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BRN51_RS16640	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BRN51_RS16655	COG0149	triose-phosphate isomerase activity
BRN51_RS16705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BRN51_RS16710	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BRN51_RS16720	COG0159	tryptophan synthase activity
BRN51_RS16730	COG0133	tryptophan synthase activity
BRN51_RS16740	COG0135	phosphoribosylanthranilate isomerase activity
BRN51_RS16745	COG0101	tRNA pseudouridine synthase activity
BRN51_RS16765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BRN51_RS16770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BRN51_RS16775	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BRN51_RS16780	COG2890	protein-(glutamine-N5) methyltransferase activity
BRN51_RS16845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BRN51_RS16855	COG0412	Dienelactone hydrolase
BRN51_RS16875	COG0717	Belongs to the dCTP deaminase family
BRN51_RS16880	COG0489	protein tyrosine kinase activity
BRN51_RS16925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRN51_RS16930	COG2311	Membrane
BRN51_RS16935	COG1047	Peptidyl-prolyl cis-trans
BRN51_RS16940	COG0791	NLP P60 protein
BRN51_RS16945	COG0791	NLP P60 protein
BRN51_RS16960	COG1301	dicarboxylic acid transport
BRN51_RS16965	COG1785	Belongs to the alkaline phosphatase family
BRN51_RS16970	COG0037	tRNA processing
BRN51_RS16975	COG1722	exodeoxyribonuclease VII activity
BRN51_RS16980	COG0142	geranyltranstransferase activity
BRN51_RS17005	COG0312	modulator of DNA gyrase
BRN51_RS17010	COG3028	Belongs to the UPF0307 family
BRN51_RS17015	COG0312	modulator of DNA gyrase
BRN51_RS17025	COG3164	Protein of unknown function
BRN51_RS17040	COG2968	Membrane
BRN51_RS17070	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BRN51_RS17095	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BRN51_RS17115	COG0495	leucyl-tRNA aminoacylation
BRN51_RS17125	COG3118	belongs to the thioredoxin family
BRN51_RS17190	COG3039	Transposase
BRN51_RS17210	COG3039	Transposase
BRN51_RS17305	COG2022	thiamine diphosphate biosynthetic process
BRN51_RS17320	COG0471	metal ion transport
BRN51_RS17320	COG3273	potassium ion transport
BRN51_RS17350	COG1970	mechanosensitive ion channel activity
BRN51_RS17375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BRN51_RS17405	COG0308	aminopeptidase N
BRN51_RS17410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BRN51_RS17425	COG3039	Transposase
BRN51_RS17440	COG2895	sulfate adenylyltransferase (ATP) activity
BRN51_RS17440	COG0529	Catalyzes the synthesis of activated sulfate
BRN51_RS17445	COG0175	sulfate reduction
BRN51_RS17450	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BRN51_RS17455	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BRN51_RS17460	COG0175	sulfate reduction
BRN51_RS17485	COG2205	protein histidine kinase activity
BRN51_RS17485	COG2198	Histidine kinase
BRN51_RS17485	COG0784	Response regulator, receiver
BRN51_RS17535	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BRN51_RS17540	COG3588	fructose-bisphosphate aldolase
BRN51_RS17550	COG0469	pyruvate kinase activity
BRN51_RS17560	COG0126	phosphoglycerate kinase activity
BRN51_RS17595	COG0753	catalase activity
BRN51_RS17620	COG2207	Transcriptional regulator
BRN51_RS17620	COG1917	Cupin 2, conserved barrel domain protein
BRN51_RS17640	COG1506	peptidase
BRN51_RS17640	COG0823	Involved in the tonB-independent uptake of proteins
BRN51_RS17665	COG1297	OPT oligopeptide transporter protein
BRN51_RS17685	COG0587	DNA-directed DNA polymerase activity
BRN51_RS17815	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BRN51_RS17965	COG3179	chitinase
BRN51_RS18025	COG1741	Belongs to the pirin family
BRN51_RS18030	COG1966	Carbon starvation protein
BRN51_RS18035	COG2879	small protein
BRN51_RS18070	COG3706	GGDEF domain
BRN51_RS18070	COG4251	negative regulation of phosphorylation
BRN51_RS18070	COG2203	Gaf domain
BRN51_RS18070	COG5001	Diguanylate cyclase
BRN51_RS18080	COG0629	single-stranded DNA binding
BRN51_RS18085	COG0142	geranyltranstransferase activity
BRN51_RS18115	COG0527	aspartate kinase activity
BRN51_RS18125	COG0384	phenazine biosynthesis protein PhzF
BRN51_RS18135	COG1764	response to oxidative stress
BRN51_RS18150	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BRN51_RS18155	COG1678	Uncharacterized ACR, COG1678
BRN51_RS18165	COG0519	Catalyzes the synthesis of GMP from XMP
BRN51_RS18200	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BRN51_RS18245	COG0693	protein deglycase activity
BRN51_RS18265	COG1959	2 iron, 2 sulfur cluster binding
BRN51_RS18270	COG0719	Fe-S assembly protein
BRN51_RS18275	COG0396	ATPase activity
BRN51_RS18280	COG0719	Fe-S assembly protein
BRN51_RS18285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BRN51_RS18295	COG2146	nitrite reductase [NAD(P)H] activity
BRN51_RS18330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BRN51_RS18345	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BRN51_RS18355	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BRN51_RS18360	COG0174	glutamine synthetase
BRN51_RS18395	COG0326	Molecular chaperone. Has ATPase activity
BRN51_RS18400	COG2207	Transcriptional regulator
BRN51_RS18420	COG2755	lipolytic protein G-D-S-L family
BRN51_RS18420	COG0657	acetylesterase activity
BRN51_RS18445	COG0488	(ABC) transporter
BRN51_RS18480	COG4651	solute:proton antiporter activity
BRN51_RS18480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BRN51_RS18495	COG4772	TonB-dependent receptor
BRN51_RS18505	COG4264	IucA IucC family
BRN51_RS18510	COG2814	Major facilitator Superfamily
BRN51_RS18520	COG0019	diaminopimelate decarboxylase activity
BRN51_RS18540	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BRN51_RS18580	COG4206	TonB-dependent receptor
BRN51_RS18620	COG0542	response to heat
BRN51_RS18665	COG0534	Mate efflux family protein
BRN51_RS18680	COG0336	Belongs to the RNA methyltransferase TrmD family
BRN51_RS18685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BRN51_RS18690	COG0228	four-way junction DNA binding
BRN51_RS18715	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BRN51_RS18730	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BRN51_RS18780	COG1555	photosystem II stabilization
BRN51_RS18785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BRN51_RS18800	COG3178	'Phosphotransferase
BRN51_RS18805	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BRN51_RS18815	COG0628	permease
BRN51_RS18825	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BRN51_RS18840	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BRN51_RS18860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BRN51_RS18865	COG0271	Belongs to the BolA IbaG family
BRN51_RS18875	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BRN51_RS18885	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BRN51_RS18890	COG1137	ATPase activity
BRN51_RS18905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRN51_RS18910	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BRN51_RS18915	COG1660	Displays ATPase and GTPase activities
BRN51_RS18925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRN51_RS18930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BRN51_RS18940	COG2239	Acts as a magnesium transporter
BRN51_RS18950	COG1294	oxidase, subunit
BRN51_RS18955	COG1271	oxidase subunit
BRN51_RS18975	COG1113	amino acid transport
BRN51_RS18990	COG2197	response regulator
BRN51_RS18995	COG0531	amino acid
BRN51_RS19065	COG0754	glutathionylspermidine amidase activity
BRN51_RS19090	COG1842	Phage shock protein A
BRN51_RS19105	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BRN51_RS19110	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BRN51_RS19120	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BRN51_RS19155	COG2201	protein-glutamate methylesterase activity
BRN51_RS19175	COG2201	protein-glutamate methylesterase activity
BRN51_RS19205	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BRN51_RS19250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BRN51_RS19255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BRN51_RS19280	COG3039	Transposase
BRN51_RS19295	COG0745	RESPONSE REGULATOR receiver
BRN51_RS19300	COG3039	Transposase
BRN51_RS19305	COG2205	protein histidine kinase activity
BRN51_RS19325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BRN51_RS19370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRN51_RS19370	COG3453	Protein conserved in bacteria
BRN51_RS19375	COG0725	ABC transporter, periplasmic molybdate-binding protein
BRN51_RS19380	COG4149	molybdate abc transporter
BRN51_RS19385	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BRN51_RS19405	COG0642	Histidine kinase
BRN51_RS19420	COG1028	Short-chain dehydrogenase reductase Sdr
BRN51_RS19430	COG1022	Amp-dependent synthetase and ligase
BRN51_RS19455	COG1376	ErfK ybiS ycfS ynhG family protein
BRN51_RS19460	COG0739	heme binding
BRN51_RS19470	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BRN51_RS19475	COG1301	dicarboxylic acid transport
BRN51_RS19495	COG2304	oxidoreductase activity
BRN51_RS19515	COG0714	Associated with various cellular activities
BRN51_RS19555	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BRN51_RS19580	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BRN51_RS19590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BRN51_RS19615	COG1561	YicC-like family, N-terminal region
BRN51_RS19620	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BRN51_RS19635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BRN51_RS19665	COG0006	proline dipeptidase activity
BRN51_RS19690	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BRN51_RS19700	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BRN51_RS19710	COG2912	Transglutaminase-like superfamily
BRN51_RS19715	COG1773	rubredoxin
BRN51_RS19720	COG0352	thiamine-phosphate diphosphorylase activity
BRN51_RS19755	COG0280	phosphate acetyltransferase
BRN51_RS19755	COG0281	malic enzyme
BRN51_RS19775	COG4191	Histidine kinase
BRN51_RS19790	COG0583	DNA-binding transcription factor activity
BRN51_RS19815	COG2197	response regulator
BRN51_RS19825	COG0642	Histidine kinase
BRN51_RS19845	COG2851	Citrate transporter
BRN51_RS19850	COG1028	Short-chain dehydrogenase reductase Sdr
BRN51_RS19855	COG1609	Transcriptional regulator
BRN51_RS19865	COG2211	Major facilitator Superfamily
BRN51_RS19890	COG1162	GTPase activity
BRN51_RS19915	COG0726	polysaccharide deacetylase
BRN51_RS19920	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BRN51_RS19970	COG0242	peptide deformylase activity
BRN51_RS19990	COG0714	Associated with various cellular activities
BRN51_RS20010	COG0537	adenosine 5'-monophosphoramidase activity
BRN51_RS20040	COG0314	molybdopterin synthase activity
BRN51_RS20045	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BRN51_RS20050	COG0315	cyclic pyranopterin monophosphate synthase activity
BRN51_RS20060	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BRN51_RS20065	COG1234	tRNA 3'-trailer cleavage
BRN51_RS20070	COG3642	lipopolysaccharide core region biosynthetic process
BRN51_RS20075	COG0859	PFAM glycosyl transferase family 9
BRN51_RS20085	COG0582	viral genome integration into host DNA
BRN51_RS20160	COG0631	protein serine/threonine phosphatase activity
BRN51_RS20195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BRN51_RS20225	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BRN51_RS20235	COG0544	peptidyl-prolyl cis-trans isomerase activity
BRN51_RS20290	COG0473	3-isopropylmalate dehydrogenase activity
BRN51_RS20315	COG4783	chaperone-mediated protein folding
BRN51_RS20330	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BRN51_RS20340	COG0438	transferase activity, transferring glycosyl groups
BRN51_RS20345	COG0671	phosphoesterase, PA-phosphatase related
BRN51_RS20350	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BRN51_RS20375	COG2833	Protein of unknown function (DUF455)
BRN51_RS20395	COG0285	dihydrofolate synthase activity
BRN51_RS20405	COG0406	alpha-ribazole phosphatase activity
BRN51_RS20440	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BRN51_RS20445	COG4208	sulfate ABC transporter
BRN51_RS20450	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BRN51_RS20455	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BRN51_RS20460	COG0156	8-amino-7-oxononanoate synthase activity
BRN51_RS20490	COG0604	alcohol dehydrogenase
BRN51_RS20495	COG1902	pentaerythritol trinitrate reductase activity
BRN51_RS20495	COG0446	pyridine nucleotide-disulphide oxidoreductase
BRN51_RS20525	COG0584	glycerophosphoryl diester phosphodiesterase
BRN51_RS20555	COG3039	Transposase
BRN51_RS20575	COG0625	glutathione transferase activity
BRN51_RS20580	COG0039	L-malate dehydrogenase activity
BRN51_RS20585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BRN51_RS20590	COG1217	gtp-binding protein TYPA
BRN51_RS20610	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BRN51_RS20765	COG3781	membrane
BRN51_RS20775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BRN51_RS20805	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BRN51_RS20825	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BRN51_RS20850	COG3710	Transcriptional regulator
BRN51_RS20855	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BRN51_RS20865	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BRN51_RS20895	COG2226	methyltransferase
BRN51_RS20900	COG0066	3-isopropylmalate dehydratase activity
BRN51_RS20905	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BRN51_RS20935	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BRN51_RS20940	COG1538	Outer membrane efflux protein
BRN51_RS20945	COG1519	Transferase
BRN51_RS20950	COG1560	Kdo2-lipid A biosynthetic process
BRN51_RS21000	COG0308	aminopeptidase N
BRN51_RS21005	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BRN51_RS21015	COG0330	HflC and HflK could
BRN51_RS21020	COG0330	HflC and HflK could
BRN51_RS21040	COG0678	peroxiredoxin activity
BRN51_RS21050	COG2826	transposase and inactivated derivatives, IS30 family
BRN51_RS21165	COG3829	transcription factor binding
BRN51_RS21190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BRN51_RS21195	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BRN51_RS21205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BRN51_RS21210	COG1028	Short-chain dehydrogenase reductase Sdr
BRN51_RS21235	COG1399	metal-binding, possibly nucleic acid-binding protein
BRN51_RS21280	COG1518	maintenance of DNA repeat elements
BRN51_RS21285	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BRN51_RS21340	COG2188	Transcriptional regulator
BRN51_RS21355	COG1450	Type ii and iii secretion system protein
BRN51_RS21370	COG3166	PFAM Fimbrial assembly family protein
BRN51_RS21375	COG3156	type II secretion system protein K
BRN51_RS21380	COG4795	General secretion pathway protein
BRN51_RS21385	COG2165	general secretion pathway protein
BRN51_RS21390	COG4970	Tfp pilus assembly protein FimT
BRN51_RS21395	COG2165	general secretion pathway protein
BRN51_RS21400	COG1459	type II secretion system
BRN51_RS21410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BRN51_RS21420	COG5295	Hep Hag repeat protein
BRN51_RS21430	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BRN51_RS21430	COG0047	phosphoribosylformylglycinamidine synthase activity
BRN51_RS21435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BRN51_RS21440	COG4974	Belongs to the 'phage' integrase family
BRN51_RS21455	COG0795	lipopolysaccharide-transporting ATPase activity
BRN51_RS21465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BRN51_RS21480	COG0525	valine-tRNA ligase activity
BRN51_RS21510	COG3039	Transposase
BRN51_RS21545	COG3039	Transposase
BRN51_RS21580	COG1183	phosphatidylcholine synthase activity
BRN51_RS21590	COG0442	prolyl-tRNA aminoacylation
BRN51_RS21605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BRN51_RS21610	COG1127	ABC transporter
BRN51_RS21615	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BRN51_RS21615	COG3218	ABC-type transport auxiliary lipoprotein component
BRN51_RS21655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BRN51_RS21660	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BRN51_RS21660	COG0662	Cupin 2, conserved barrel domain protein
BRN51_RS21685	COG2086	electron transfer activity
BRN51_RS21710	COG3328	transposase activity
BRN51_RS21760	COG0626	cystathionine gamma-synthase activity
BRN51_RS21790	COG0625	glutathione transferase activity
BRN51_RS21805	COG0513	Belongs to the DEAD box helicase family
BRN51_RS21815	COG0720	synthase
BRN51_RS21825	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BRN51_RS21830	COG1956	GAF domain-containing protein
BRN51_RS21870	COG0339	signal peptide processing
BRN51_RS21920	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BRN51_RS21925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRN51_RS21980	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BRN51_RS21985	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BRN51_RS21990	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BRN51_RS21995	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BRN51_RS22000	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BRN51_RS22005	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BRN51_RS22015	COG0356	it plays a direct role in the translocation of protons across the membrane
BRN51_RS22035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BRN51_RS22045	COG0508	dehydrogenase complex catalyzes the overall conversion of
BRN51_RS22075	COG2011	ABC-type metal ion transport system permease component
BRN51_RS22085	COG0697	spore germination
BRN51_RS22125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BRN51_RS22130	COG1187	pseudouridine synthase activity
BRN51_RS22135	COG2813	Specifically methylates the guanine in position
BRN51_RS22165	COG2202	Pas domain
BRN51_RS22165	COG2205	protein histidine kinase activity
BRN51_RS22190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRN51_RS22240	COG0745	RESPONSE REGULATOR receiver
BRN51_RS22255	COG1404	Belongs to the peptidase S8 family
BRN51_RS22270	COG0842	Transport permease protein
BRN51_RS22275	COG1131	(ABC) transporter
BRN51_RS22280	COG0025	NhaP-type Na H and K H
BRN51_RS22295	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BRN51_RS22305	COG1573	uracil-dna glycosylase
BRN51_RS22315	COG3384	dioxygenase
BRN51_RS22330	COG0667	Aldo Keto reductase
BRN51_RS22345	COG3590	peptidase
BRN51_RS22365	COG0531	amino acid
BRN51_RS22380	COG2972	Histidine kinase
BRN51_RS22445	COG1271	oxidase subunit
BRN51_RS22480	COG1324	tolerance protein
BRN51_RS22500	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BRN51_RS22505	COG0511	ligase activity, forming carbon-carbon bonds
BRN51_RS22515	COG0439	Biotin carboxylase
BRN51_RS22575	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BRN51_RS22705	COG2831	hemolysin activation secretion protein
BRN51_RS22730	COG2453	phosphatase
BRN51_RS22730	COG0671	phosphoesterase, PA-phosphatase related
BRN51_RS22735	COG2267	carboxylic ester hydrolase activity
BRN51_RS22745	COG2267	carboxylic ester hydrolase activity
BRN51_RS22755	COG0138	bifunctional purine biosynthesis protein purh
BRN51_RS22760	COG0151	Belongs to the GarS family
BRN51_RS22765	COG1136	(ABC) transporter
BRN51_RS22765	COG0577	efflux transmembrane transporter activity
BRN51_RS22775	COG1289	transmembrane transporter activity
BRN51_RS22790	COG2814	Major facilitator Superfamily
BRN51_RS22815	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BRN51_RS22850	COG0745	RESPONSE REGULATOR receiver
BRN51_RS22895	COG0739	heme binding
BRN51_RS22910	COG2211	Major facilitator Superfamily
BRN51_RS22915	COG0708	Exodeoxyribonuclease III
BRN51_RS22930	COG1192	Involved in chromosome partitioning
BRN51_RS22935	COG1475	DNA binding
BRN51_RS22950	COG0463	Glycosyl transferase, family 2
BRN51_RS22970	COG0756	dUTP diphosphatase activity
BRN51_RS22975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BRN51_RS22980	COG2003	Belongs to the UPF0758 family
BRN51_RS22985	COG0018	arginyl-trna synthetase
BRN51_RS23000	COG4221	oxidoreductase activity
BRN51_RS23025	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BRN51_RS23030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BRN51_RS23045	COG3485	protocatechuate 3,4-dioxygenase
BRN51_RS23050	COG3485	protocatechuate 3,4-dioxygenase
BRN51_RS23090	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BRN51_RS23100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BRN51_RS23115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BRN51_RS23115	COG0045	succinate-CoA ligase (ADP-forming) activity
BRN51_RS23115	COG1042	CoA-binding domain protein
BRN51_RS23125	COG2239	Acts as a magnesium transporter
BRN51_RS23140	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BRN51_RS23160	COG3100	YcgL domain-containing protein
BRN51_RS23165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BRN51_RS23175	COG0463	Glycosyl transferase, family 2
BRN51_RS23190	COG1028	Short-chain dehydrogenase reductase Sdr
BRN51_RS23205	COG0156	8-amino-7-oxononanoate synthase activity
BRN51_RS23210	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BRN51_RS23215	COG1040	competence protein
BRN51_RS23220	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BRN51_RS23235	COG0628	permease
BRN51_RS23245	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BRN51_RS23255	COG1595	DNA-templated transcription, initiation
BRN51_RS23260	COG0753	catalase activity
BRN51_RS23305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRN51_RS23310	COG0180	Tryptophanyl-tRNA synthetase
BRN51_RS23315	COG3237	CsbD-like
BRN51_RS23355	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BRN51_RS23370	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BRN51_RS23375	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BRN51_RS23375	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BRN51_RS23415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BRN51_RS23445	COG1566	PFAM secretion protein HlyD family protein
BRN51_RS23465	COG1199	ATP-dependent helicase activity
BRN51_RS23500	COG0583	DNA-binding transcription factor activity
BRN51_RS23550	COG0625	glutathione transferase activity
BRN51_RS23585	COG4555	ABC transporter
BRN51_RS23595	COG1476	TRANSCRIPTIONal
BRN51_RS23615	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BRN51_RS23620	COG1131	(ABC) transporter
BRN51_RS23625	COG0842	Transport permease protein
BRN51_RS23635	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BRN51_RS23720	COG1181	Belongs to the D-alanine--D-alanine ligase family
BRN51_RS23735	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BRN51_RS23745	COG0564	pseudouridine synthase activity
BRN51_RS23775	COG0339	signal peptide processing
BRN51_RS23805	COG3254	rhamnose metabolic process
BRN51_RS23810	COG0738	Major facilitator superfamily
BRN51_RS23815	COG1414	Transcriptional regulator
BRN51_RS23830	COG2205	protein histidine kinase activity
BRN51_RS23845	COG3459	Glycosyltransferase 36 associated
BRN51_RS23850	COG2211	Major facilitator Superfamily
BRN51_RS23855	COG3265	gluconokinase activity
BRN51_RS23865	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BRN51_RS23945	COG1127	ABC transporter
BRN51_RS23950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BRN51_RS23955	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BRN51_RS23970	COG2853	Lipoprotein
BRN51_RS23995	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BRN51_RS24060	COG0676	glucose-6-phosphate 1-epimerase activity
BRN51_RS24085	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BRN51_RS24095	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BRN51_RS24105	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BRN51_RS24115	COG1064	alcohol dehydrogenase
BRN51_RS24160	COG1522	sequence-specific DNA binding
BRN51_RS24165	COG3186	Phenylalanine-4-hydroxylase
BRN51_RS24180	COG2755	lipolytic protein G-D-S-L family
BRN51_RS24205	COG0656	L-ascorbic acid biosynthetic process
BRN51_RS24210	COG2130	NADP-dependent
BRN51_RS24215	COG0667	Aldo Keto reductase
BRN51_RS24225	COG1187	pseudouridine synthase activity
BRN51_RS24240	COG1643	Atp-dependent helicase
BRN51_RS24245	COG4807	Protein conserved in bacteria
BRN51_RS24250	COG4948	Mandelate Racemase Muconate Lactonizing
BRN51_RS24260	COG0179	Fumarylacetoacetate (FAA) hydrolase
BRN51_RS24265	COG1028	Short-chain dehydrogenase reductase Sdr
BRN51_RS24285	COG3507	Belongs to the glycosyl hydrolase 43 family
BRN51_RS24330	COG3162	membrane
BRN51_RS24335	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BRN51_RS24350	COG0708	Exodeoxyribonuclease III
BRN51_RS24365	COG2091	lysine biosynthetic process via aminoadipic acid
BRN51_RS24375	COG3540	Alkaline phosphatase
BRN51_RS24380	COG0357	Ribosomal RNA small subunit methyltransferase G
BRN51_RS24400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BRN51_RS24405	COG2159	amidohydrolase
BRN51_RS24420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BRN51_RS24425	COG0583	DNA-binding transcription factor activity
BRN51_RS24430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BRN51_RS24450	COG0210	DNA helicase
BRN51_RS24465	COG0531	amino acid
BRN51_RS24475	COG1322	Protein conserved in bacteria
BRN51_RS24485	COG0386	Belongs to the glutathione peroxidase family
BRN51_RS24540	COG0793	Belongs to the peptidase S41A family
BRN51_RS24545	COG4942	peptidase
BRN51_RS24555	COG2234	aminopeptidase activity
BRN51_RS24605	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BRN51_RS24610	COG0302	gtp cyclohydrolase
BRN51_RS24630	COG0477	Major facilitator Superfamily
BRN51_RS24645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BRN51_RS24760	COG1929	Belongs to the glycerate kinase type-1 family
BRN51_RS24765	COG2271	Major facilitator Superfamily
BRN51_RS24780	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BRN51_RS24790	COG0861	Integral membrane protein TerC family
BRN51_RS24800	COG0584	glycerophosphoryl diester phosphodiesterase
BRN51_RS24810	COG0671	phosphoesterase, PA-phosphatase related
BRN51_RS24815	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BRN51_RS24820	COG0726	polysaccharide deacetylase
BRN51_RS24825	COG0706	membrane insertase activity