locus-tag	class	description
ATY45_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ATY45_RS00020	COG0187	DNA topoisomerase II activity
ATY45_RS00030	COG0501	Belongs to the peptidase M48B family
ATY45_RS00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ATY45_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ATY45_RS00080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ATY45_RS00090	COG4772	TonB-dependent receptor
ATY45_RS00105	COG3039	Transposase
ATY45_RS00110	COG1304	FMN binding
ATY45_RS00115	COG1755	Isoprenylcysteine carboxyl methyltransferase
ATY45_RS00130	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ATY45_RS00135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATY45_RS00165	COG3039	Transposase
ATY45_RS00235	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS00260	COG3039	Transposase
ATY45_RS00270	COG1090	epimerase
ATY45_RS00275	COG0642	Histidine kinase
ATY45_RS00285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ATY45_RS00390	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ATY45_RS00475	COG1511	domain protein
ATY45_RS00475	COG3264	Mechanosensitive ion channel
ATY45_RS00485	COG3293	Transposase
ATY45_RS00495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ATY45_RS00500	COG2354	Protein conserved in bacteria
ATY45_RS00505	COG1649	PFAM Uncharacterised BCR, COG1649
ATY45_RS00525	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ATY45_RS00550	COG0702	epimerase
ATY45_RS00560	COG1858	cytochrome C peroxidase
ATY45_RS00625	COG0513	Belongs to the DEAD box helicase family
ATY45_RS00635	COG3039	Transposase
ATY45_RS00680	COG1272	protein, Hemolysin III
ATY45_RS00685	COG1205	dead DEAH box helicase
ATY45_RS00685	COG1111	helicase
ATY45_RS00740	COG0069	glutamate synthase activity
ATY45_RS00740	COG0067	glutamate synthase
ATY45_RS00740	COG0070	glutamate synthase
ATY45_RS00745	COG0493	'glutamate synthase
ATY45_RS00765	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS00795	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ATY45_RS00800	COG1609	Transcriptional regulator
ATY45_RS00825	COG0366	Alpha amylase catalytic
ATY45_RS00830	COG0366	Alpha amylase catalytic
ATY45_RS00835	COG2801	Transposase and inactivated derivatives
ATY45_RS00850	COG3328	transposase activity
ATY45_RS00885	COG0606	chelatase, subunit chli
ATY45_RS00925	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ATY45_RS00930	COG1166	arginine decarboxylase activity
ATY45_RS00975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ATY45_RS01000	COG1028	Short-chain dehydrogenase reductase Sdr
ATY45_RS01015	COG2801	Transposase and inactivated derivatives
ATY45_RS01025	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ATY45_RS01040	COG0210	DNA helicase
ATY45_RS01055	COG3132	Protein of unknown function, DUF480
ATY45_RS01060	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ATY45_RS01065	COG0284	orotidine-5'-phosphate decarboxylase activity
ATY45_RS01095	COG2937	Belongs to the GPAT DAPAT family
ATY45_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
ATY45_RS01100	COG3321	synthase
ATY45_RS01100	COG0604	alcohol dehydrogenase
ATY45_RS01115	COG2963	transposase activity
ATY45_RS01120	COG3328	transposase activity
ATY45_RS01155	COG1752	Esterase of the alpha-beta hydrolase superfamily
ATY45_RS01165	COG1119	ATPase activity
ATY45_RS01180	COG1125	glycine betaine transport
ATY45_RS01180	COG0517	IMP dehydrogenase activity
ATY45_RS01195	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ATY45_RS01200	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ATY45_RS01205	COG3550	peptidyl-serine autophosphorylation
ATY45_RS01210	COG1396	sequence-specific DNA binding
ATY45_RS01230	COG0489	protein tyrosine kinase activity
ATY45_RS01235	COG2062	phosphohistidine phosphatase, SixA
ATY45_RS01245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ATY45_RS01290	COG1968	undecaprenyl-diphosphatase activity
ATY45_RS01295	COG0174	glutamine synthetase
ATY45_RS01300	COG0347	Belongs to the P(II) protein family
ATY45_RS01305	COG0004	ammonium transporteR
ATY45_RS01310	COG3852	Histidine kinase
ATY45_RS01315	COG2204	response regulator
ATY45_RS01320	COG2032	superoxide dismutase activity
ATY45_RS01325	COG2032	superoxide dismutase activity
ATY45_RS01360	COG1196	nuclear chromosome segregation
ATY45_RS01385	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ATY45_RS01390	COG1074	ATP-dependent DNA helicase activity
ATY45_RS01400	COG3549	Plasmid maintenance system killer
ATY45_RS01475	COG1764	response to oxidative stress
ATY45_RS01480	COG1846	Transcriptional regulator
ATY45_RS01535	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ATY45_RS01545	COG3293	Transposase
ATY45_RS01585	COG2211	Major facilitator Superfamily
ATY45_RS01605	COG3693	PFAM glycoside hydrolase, family 10
ATY45_RS01610	COG3693	PFAM glycoside hydrolase, family 10
ATY45_RS01635	COG0246	Mannitol dehydrogenase
ATY45_RS01640	COG1472	Belongs to the glycosyl hydrolase 3 family
ATY45_RS01650	COG4948	Mandelate Racemase Muconate Lactonizing
ATY45_RS01660	COG3661	Belongs to the glycosyl hydrolase 67 family
ATY45_RS01680	COG2974	May be involved in recombination
ATY45_RS01705	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ATY45_RS01715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ATY45_RS01725	COG0805	protein transport
ATY45_RS01735	COG0519	Catalyzes the synthesis of GMP from XMP
ATY45_RS01735	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ATY45_RS01750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ATY45_RS01755	COG0752	glycyl-tRNA synthetase alpha subunit
ATY45_RS01765	COG0457	Tetratricopeptide repeat
ATY45_RS01770	COG4771	TonB-dependent receptor
ATY45_RS01785	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ATY45_RS01795	COG0697	spore germination
ATY45_RS01805	COG0523	cobalamin synthesis protein
ATY45_RS01865	COG1960	acyl-CoA dehydrogenase activity
ATY45_RS01870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ATY45_RS01875	COG4770	biotin carboxylase activity
ATY45_RS01885	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS01900	COG2351	hydroxyisourate hydrolase activity
ATY45_RS01920	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ATY45_RS01965	COG0084	hydrolase, TatD family'
ATY45_RS01980	COG0583	DNA-binding transcription factor activity
ATY45_RS01985	COG2814	Major facilitator Superfamily
ATY45_RS01995	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ATY45_RS02000	COG1902	pentaerythritol trinitrate reductase activity
ATY45_RS02030	COG0745	RESPONSE REGULATOR receiver
ATY45_RS02035	COG2205	protein histidine kinase activity
ATY45_RS02040	COG2205	protein histidine kinase activity
ATY45_RS02055	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ATY45_RS02060	COG0583	DNA-binding transcription factor activity
ATY45_RS02090	COG0702	epimerase
ATY45_RS02095	COG1733	regulation of RNA biosynthetic process
ATY45_RS02165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ATY45_RS02200	COG2911	Protein conserved in bacteria
ATY45_RS02205	COG0729	surface antigen
ATY45_RS02215	COG2963	transposase activity
ATY45_RS02225	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ATY45_RS02230	COG3118	belongs to the thioredoxin family
ATY45_RS02240	COG2884	Cell division ATP-binding protein ftsE
ATY45_RS02245	COG2177	Part of the ABC transporter FtsEX involved in
ATY45_RS02250	COG2201	protein-glutamate methylesterase activity
ATY45_RS02255	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ATY45_RS02260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ATY45_RS02270	COG1252	NADH dehydrogenase
ATY45_RS02305	COG0459	protein refolding
ATY45_RS02315	COG4771	TonB-dependent receptor
ATY45_RS02330	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ATY45_RS02370	COG3386	PFAM SMP-30 Gluconolaconase
ATY45_RS02385	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ATY45_RS02420	COG2353	YceI-like domain
ATY45_RS02505	COG3328	transposase activity
ATY45_RS02525	COG0408	coproporphyrinogen oxidase activity
ATY45_RS02540	COG3039	Transposase
ATY45_RS02560	COG0129	dihydroxy-acid dehydratase activity
ATY45_RS02570	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ATY45_RS02600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ATY45_RS02605	COG0318	PFAM AMP-dependent synthetase and ligase
ATY45_RS02610	COG0727	PFAM Uncharacterised protein family (UPF0153)
ATY45_RS02615	COG0596	Alpha beta hydrolase
ATY45_RS02630	COG3177	Filamentation induced by cAMP protein fic
ATY45_RS02635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ATY45_RS02650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ATY45_RS02675	COG4191	Histidine kinase
ATY45_RS02680	COG0028	Belongs to the TPP enzyme family
ATY45_RS02695	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ATY45_RS02700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ATY45_RS02725	COG5383	Protein conserved in bacteria
ATY45_RS02735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ATY45_RS02740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ATY45_RS02745	COG1473	amidohydrolase
ATY45_RS02755	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ATY45_RS02755	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ATY45_RS02760	COG3328	transposase activity
ATY45_RS02865	COG0358	DNA primase activity
ATY45_RS02870	COG1295	ribonuclease BN
ATY45_RS02880	COG3293	Transposase
ATY45_RS02890	COG1610	YqeY-like protein
ATY45_RS02900	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ATY45_RS02905	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ATY45_RS02915	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS02935	COG3293	Transposase
ATY45_RS02965	COG2133	pyrroloquinoline quinone binding
ATY45_RS02975	COG4682	membrane
ATY45_RS02995	COG3293	Transposase
ATY45_RS03005	COG0531	amino acid
ATY45_RS03035	COG4948	Mandelate Racemase Muconate Lactonizing
ATY45_RS03045	COG3023	N-Acetylmuramoyl-L-alanine amidase
ATY45_RS03050	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ATY45_RS03125	COG0183	Belongs to the thiolase family
ATY45_RS03140	COG0022	dehydrogenase e1 component
ATY45_RS03155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ATY45_RS03160	COG3483	tryptophan 2,3-dioxygenase activity
ATY45_RS03165	COG3104	oligopeptide transport
ATY45_RS03190	COG1320	monovalent cation:proton antiporter activity
ATY45_RS03195	COG2212	antiporter activity
ATY45_RS03205	COG0651	ATP synthesis coupled electron transport
ATY45_RS03210	COG1006	Multisubunit Na H antiporter MnhC subunit
ATY45_RS03215	COG2111	Na H antiporter
ATY45_RS03215	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ATY45_RS03270	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ATY45_RS03280	COG0456	acetyltransferase
ATY45_RS03300	COG2963	transposase activity
ATY45_RS03315	COG4221	oxidoreductase activity
ATY45_RS03385	COG0697	spore germination
ATY45_RS03390	COG4305	rare lipoprotein A
ATY45_RS03395	COG5297	Belongs to the glycosyl hydrolase family 6
ATY45_RS03400	COG1113	amino acid transport
ATY45_RS03410	COG0598	Magnesium transport protein CorA
ATY45_RS03450	COG3293	Transposase
ATY45_RS03485	COG0840	transmembrane signaling receptor activity
ATY45_RS03495	COG5297	Belongs to the glycosyl hydrolase family 6
ATY45_RS03495	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ATY45_RS03500	COG0659	secondary active sulfate transmembrane transporter activity
ATY45_RS03530	COG3293	Transposase
ATY45_RS03550	COG3275	phosphorelay sensor kinase activity
ATY45_RS03560	COG0181	hydroxymethylbilane synthase activity
ATY45_RS03585	COG1505	serine-type exopeptidase activity
ATY45_RS03600	COG0436	Aminotransferase
ATY45_RS03630	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ATY45_RS03660	COG0308	aminopeptidase N
ATY45_RS03665	COG2199	diguanylate cyclase activity
ATY45_RS03720	COG3039	Transposase
ATY45_RS03725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATY45_RS03730	COG1077	Cell shape determining protein MreB Mrl
ATY45_RS03735	COG1792	Involved in formation and maintenance of cell shape
ATY45_RS03750	COG0772	Belongs to the SEDS family
ATY45_RS03795	COG3039	Transposase
ATY45_RS03810	COG2951	lytic endotransglycosylase activity
ATY45_RS03815	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ATY45_RS03825	COG1686	Belongs to the peptidase S11 family
ATY45_RS03835	COG2921	Belongs to the UPF0250 family
ATY45_RS03860	COG1051	belongs to the nudix hydrolase family
ATY45_RS03860	COG1056	cytidyltransferase-related domain
ATY45_RS03900	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ATY45_RS03905	COG0673	inositol 2-dehydrogenase activity
ATY45_RS03910	COG2823	Periplasmic or secreted lipoprotein
ATY45_RS03915	COG4251	negative regulation of phosphorylation
ATY45_RS03920	COG0784	Response regulator, receiver
ATY45_RS03925	COG4191	Histidine kinase
ATY45_RS03930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ATY45_RS03950	COG2801	Transposase and inactivated derivatives
ATY45_RS03970	COG3250	beta-galactosidase activity
ATY45_RS03985	COG2188	Transcriptional regulator
ATY45_RS03995	COG1609	Transcriptional regulator
ATY45_RS04000	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ATY45_RS04005	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ATY45_RS04015	COG1215	transferase activity, transferring glycosyl groups
ATY45_RS04020	COG0726	polysaccharide deacetylase
ATY45_RS04020	COG1649	PFAM Uncharacterised BCR, COG1649
ATY45_RS04055	COG3293	Transposase
ATY45_RS04105	COG3039	Transposase
ATY45_RS04110	COG3039	Transposase
ATY45_RS04115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ATY45_RS04120	COG3039	Transposase
ATY45_RS04125	COG2963	transposase activity
ATY45_RS04135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ATY45_RS04160	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ATY45_RS04205	COG2205	protein histidine kinase activity
ATY45_RS04235	COG3791	Glutathione-dependent formaldehyde-activating
ATY45_RS04260	COG0488	(ABC) transporter
ATY45_RS04280	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ATY45_RS04300	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ATY45_RS04300	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ATY45_RS04320	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ATY45_RS04325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ATY45_RS04330	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ATY45_RS04365	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ATY45_RS04370	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ATY45_RS04380	COG2205	protein histidine kinase activity
ATY45_RS04385	COG0745	RESPONSE REGULATOR receiver
ATY45_RS04390	COG0277	FAD linked oxidase domain protein
ATY45_RS04395	COG1988	membrane-bound metal-dependent
ATY45_RS04400	COG0792	nuclease activity
ATY45_RS04435	COG0275	rRNA processing
ATY45_RS04440	COG3116	cell division
ATY45_RS04455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ATY45_RS04475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ATY45_RS04480	COG1181	Belongs to the D-alanine--D-alanine ligase family
ATY45_RS04485	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ATY45_RS04500	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ATY45_RS04510	COG4942	peptidase
ATY45_RS04510	COG1388	LysM domain
ATY45_RS04525	COG0494	nUDIX hydrolase
ATY45_RS04540	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ATY45_RS04550	COG3321	synthase
ATY45_RS04550	COG1028	Short-chain dehydrogenase reductase Sdr
ATY45_RS04550	COG0604	alcohol dehydrogenase
ATY45_RS04595	COG3039	Transposase
ATY45_RS04615	COG2226	methyltransferase
ATY45_RS04620	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ATY45_RS04660	COG3293	Transposase
ATY45_RS04670	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ATY45_RS04680	COG4106	trans-aconitate 2-methyltransferase activity
ATY45_RS04685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ATY45_RS04695	COG3039	Transposase
ATY45_RS04700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATY45_RS04705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ATY45_RS04715	COG0667	Aldo Keto reductase
ATY45_RS04755	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ATY45_RS04765	COG2175	clavaminate synthase activity
ATY45_RS04775	COG4181	ATPase activity
ATY45_RS04790	COG0642	Histidine kinase
ATY45_RS04805	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ATY45_RS04825	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ATY45_RS04850	COG2967	ApaG domain
ATY45_RS04855	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ATY45_RS04865	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ATY45_RS04880	COG0123	including yeast histone deacetylase and acetoin utilization protein
ATY45_RS04885	COG2096	Adenosyltransferase
ATY45_RS04895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ATY45_RS04900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ATY45_RS04940	COG0583	DNA-binding transcription factor activity
ATY45_RS04945	COG0318	PFAM AMP-dependent synthetase and ligase
ATY45_RS04955	COG1024	Enoyl-CoA hydratase
ATY45_RS04975	COG3386	PFAM SMP-30 Gluconolaconase
ATY45_RS05025	COG3293	Transposase
ATY45_RS05035	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS05070	COG2197	response regulator
ATY45_RS05100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ATY45_RS05105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ATY45_RS05110	COG0583	DNA-binding transcription factor activity
ATY45_RS05115	COG3634	alkyl hydroperoxide reductase activity
ATY45_RS05125	COG2890	protein-(glutamine-N5) methyltransferase activity
ATY45_RS05165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ATY45_RS05165	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ATY45_RS05180	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ATY45_RS05205	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ATY45_RS05230	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ATY45_RS05235	COG1404	Belongs to the peptidase S8 family
ATY45_RS05240	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ATY45_RS05265	COG1295	ribonuclease BN
ATY45_RS05270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ATY45_RS05290	COG0521	Mo-molybdopterin cofactor biosynthetic process
ATY45_RS05300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ATY45_RS05315	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ATY45_RS05330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ATY45_RS05340	COG0193	aminoacyl-tRNA hydrolase activity
ATY45_RS05345	COG0012	GTP binding
ATY45_RS05375	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ATY45_RS05380	COG0250	Participates in transcription elongation, termination and antitermination
ATY45_RS05385	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ATY45_RS05395	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ATY45_RS05400	COG0222	ribosome binding
ATY45_RS05405	COG0085	RNA polymerase activity
ATY45_RS05410	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ATY45_RS05415	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ATY45_RS05420	COG0049	tRNA binding
ATY45_RS05435	COG0051	transcription antitermination factor activity, RNA binding
ATY45_RS05440	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ATY45_RS05445	COG0088	Forms part of the polypeptide exit tunnel
ATY45_RS05450	COG0089	rRNA binding
ATY45_RS05475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ATY45_RS05480	COG0255	Belongs to the universal ribosomal protein uL29 family
ATY45_RS05485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ATY45_RS05490	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ATY45_RS05495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ATY45_RS05500	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ATY45_RS05520	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ATY45_RS05530	COG1841	ribosomal large subunit assembly
ATY45_RS05540	COG0201	protein transport
ATY45_RS05550	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ATY45_RS05555	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ATY45_RS05565	COG0203	ribosomal protein L17
ATY45_RS05590	COG2963	transposase activity
ATY45_RS05635	COG3551	Protein conserved in bacteria
ATY45_RS05665	COG2194	sulfuric ester hydrolase activity
ATY45_RS05675	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ATY45_RS05680	COG0745	RESPONSE REGULATOR receiver
ATY45_RS05685	COG0642	Histidine kinase
ATY45_RS05695	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ATY45_RS05700	COG2894	cell division
ATY45_RS05725	COG4585	Histidine kinase
ATY45_RS05730	COG2197	response regulator
ATY45_RS05745	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ATY45_RS05775	COG2963	transposase activity
ATY45_RS05835	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ATY45_RS05845	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ATY45_RS05905	COG2801	Transposase and inactivated derivatives
ATY45_RS05910	COG2963	transposase activity
ATY45_RS06115	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ATY45_RS06135	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ATY45_RS06140	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
ATY45_RS06145	COG0732	type I restriction modification DNA specificity domain
ATY45_RS06150	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ATY45_RS06235	COG0587	DNA-directed DNA polymerase activity
ATY45_RS06250	COG1297	OPT oligopeptide transporter protein
ATY45_RS06275	COG1506	peptidase
ATY45_RS06275	COG0823	Involved in the tonB-independent uptake of proteins
ATY45_RS06300	COG2207	Transcriptional regulator
ATY45_RS06300	COG1917	Cupin 2, conserved barrel domain protein
ATY45_RS06325	COG0753	catalase activity
ATY45_RS06345	COG3039	Transposase
ATY45_RS06365	COG0126	phosphoglycerate kinase activity
ATY45_RS06375	COG0469	pyruvate kinase activity
ATY45_RS06380	COG3588	fructose-bisphosphate aldolase
ATY45_RS06385	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ATY45_RS06435	COG0784	Response regulator, receiver
ATY45_RS06435	COG2198	Histidine kinase
ATY45_RS06435	COG2205	protein histidine kinase activity
ATY45_RS06455	COG0175	sulfate reduction
ATY45_RS06460	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ATY45_RS06465	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ATY45_RS06470	COG0175	sulfate reduction
ATY45_RS06475	COG0529	Catalyzes the synthesis of activated sulfate
ATY45_RS06475	COG2895	sulfate adenylyltransferase (ATP) activity
ATY45_RS06485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ATY45_RS06490	COG0308	aminopeptidase N
ATY45_RS06520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ATY45_RS06525	COG2272	Belongs to the type-B carboxylesterase lipase family
ATY45_RS06550	COG1970	mechanosensitive ion channel activity
ATY45_RS06560	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS06595	COG0471	metal ion transport
ATY45_RS06595	COG3273	potassium ion transport
ATY45_RS06605	COG2022	thiamine diphosphate biosynthetic process
ATY45_RS06640	COG2963	transposase activity
ATY45_RS06675	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS06680	COG3293	Transposase
ATY45_RS06705	COG3039	Transposase
ATY45_RS06720	COG3293	Transposase
ATY45_RS06730	COG3039	Transposase
ATY45_RS06775	COG3293	Transposase
ATY45_RS06790	COG3118	belongs to the thioredoxin family
ATY45_RS06815	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ATY45_RS06840	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ATY45_RS06875	COG3039	Transposase
ATY45_RS06885	COG2968	Membrane
ATY45_RS06900	COG3164	Protein of unknown function
ATY45_RS06920	COG0312	modulator of DNA gyrase
ATY45_RS06930	COG0312	modulator of DNA gyrase
ATY45_RS06950	COG0142	geranyltranstransferase activity
ATY45_RS06955	COG1722	exodeoxyribonuclease VII activity
ATY45_RS06960	COG0037	tRNA processing
ATY45_RS06965	COG1785	Belongs to the alkaline phosphatase family
ATY45_RS06970	COG1301	dicarboxylic acid transport
ATY45_RS06985	COG0791	NLP P60 protein
ATY45_RS06990	COG0791	NLP P60 protein
ATY45_RS06995	COG1047	Peptidyl-prolyl cis-trans
ATY45_RS07000	COG2311	Membrane
ATY45_RS07005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATY45_RS07040	COG0489	protein tyrosine kinase activity
ATY45_RS07045	COG0717	Belongs to the dCTP deaminase family
ATY45_RS07060	COG0412	Dienelactone hydrolase
ATY45_RS07070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ATY45_RS07090	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS07095	COG0433	COG0433 Predicted ATPase
ATY45_RS07120	COG2890	protein-(glutamine-N5) methyltransferase activity
ATY45_RS07125	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ATY45_RS07130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ATY45_RS07135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ATY45_RS07155	COG0101	tRNA pseudouridine synthase activity
ATY45_RS07160	COG0135	phosphoribosylanthranilate isomerase activity
ATY45_RS07170	COG0133	tryptophan synthase activity
ATY45_RS07190	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ATY45_RS07195	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATY45_RS07225	COG3293	Transposase
ATY45_RS07250	COG0149	triose-phosphate isomerase activity
ATY45_RS07265	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ATY45_RS07275	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ATY45_RS07280	COG0649	NAD binding
ATY45_RS07285	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ATY45_RS07290	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ATY45_RS07295	COG1034	ATP synthesis coupled electron transport
ATY45_RS07300	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ATY45_RS07330	COG1007	ATP synthesis coupled electron transport
ATY45_RS07340	COG0779	Required for maturation of 30S ribosomal subunits
ATY45_RS07345	COG0195	Participates in both transcription termination and antitermination
ATY45_RS07350	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ATY45_RS07365	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ATY45_RS07370	COG1185	polyribonucleotide nucleotidyltransferase activity
ATY45_RS07405	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ATY45_RS07415	COG2095	MarC family integral membrane protein
ATY45_RS07430	COG1611	Belongs to the LOG family
ATY45_RS07470	COG4969	Belongs to the N-Me-Phe pilin family
ATY45_RS07475	COG0556	nucleotide-excision repair
ATY45_RS07495	COG2963	transposase activity
ATY45_RS07510	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ATY45_RS07520	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ATY45_RS07525	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ATY45_RS07580	COG0438	transferase activity, transferring glycosyl groups
ATY45_RS07585	COG0438	transferase activity, transferring glycosyl groups
ATY45_RS07595	COG0438	transferase activity, transferring glycosyl groups
ATY45_RS07715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ATY45_RS07740	COG4191	Histidine kinase
ATY45_RS07740	COG0784	Response regulator, receiver
ATY45_RS07765	COG0552	protein localization to endoplasmic reticulum
ATY45_RS07775	COG3938	Belongs to the proline racemase family
ATY45_RS07780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATY45_RS07795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ATY45_RS07805	COG0006	proline dipeptidase activity
ATY45_RS07820	COG0531	amino acid
ATY45_RS07870	COG4206	TonB-dependent receptor
ATY45_RS07895	COG4206	TonB-dependent receptor
ATY45_RS07900	COG3328	transposase activity
ATY45_RS07950	COG0746	molybdenum cofactor guanylyltransferase activity
ATY45_RS07975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ATY45_RS07975	COG1648	precorrin-2 dehydrogenase activity
ATY45_RS08045	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ATY45_RS08065	COG1054	Belongs to the UPF0176 family
ATY45_RS08075	COG3293	Transposase
ATY45_RS08090	COG1530	ribonuclease E activity
ATY45_RS08100	COG3064	Membrane
ATY45_RS08105	COG0428	transporter
ATY45_RS08110	COG0428	transporter
ATY45_RS08135	COG2801	Transposase and inactivated derivatives
ATY45_RS08175	COG3039	Transposase
ATY45_RS08280	COG0631	protein serine/threonine phosphatase activity
ATY45_RS08285	COG0515	serine threonine protein kinase
ATY45_RS08315	COG1858	cytochrome C peroxidase
ATY45_RS08325	COG4644	lycopene metabolic process
ATY45_RS08340	COG2963	transposase activity
ATY45_RS08370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ATY45_RS08375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ATY45_RS08390	COG2201	protein-glutamate methylesterase activity
ATY45_RS08420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ATY45_RS08440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ATY45_RS08455	COG1595	DNA-templated transcription, initiation
ATY45_RS08505	COG2244	polysaccharide biosynthetic process
ATY45_RS08535	COG2264	protein methyltransferase activity
ATY45_RS08545	COG0438	transferase activity, transferring glycosyl groups
ATY45_RS08560	COG1136	(ABC) transporter
ATY45_RS08565	COG1132	(ABC) transporter
ATY45_RS08575	COG0477	Major facilitator Superfamily
ATY45_RS08585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATY45_RS08600	COG1253	flavin adenine dinucleotide binding
ATY45_RS08610	COG0306	phosphate transporter
ATY45_RS08635	COG0504	CTP synthase activity
ATY45_RS08640	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ATY45_RS08650	COG0148	phosphopyruvate hydratase activity
ATY45_RS08655	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ATY45_RS08670	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ATY45_RS08680	COG2840	Smr protein MutS2
ATY45_RS08685	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ATY45_RS08690	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ATY45_RS08695	COG1238	metal cluster binding
ATY45_RS08710	COG1534	Rna-binding protein
ATY45_RS08715	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ATY45_RS08725	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ATY45_RS08730	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ATY45_RS08740	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ATY45_RS08745	COG1546	Belongs to the CinA family
ATY45_RS08760	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ATY45_RS08765	COG2137	regulation of response to DNA damage stimulus
ATY45_RS08770	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ATY45_RS08775	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ATY45_RS08795	COG0305	Participates in initiation and elongation during chromosome replication
ATY45_RS08800	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ATY45_RS08830	COG1741	Belongs to the pirin family
ATY45_RS08835	COG0583	DNA-binding transcription factor activity
ATY45_RS08865	COG0351	phosphomethylpyrimidine kinase
ATY45_RS08875	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ATY45_RS08880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ATY45_RS08895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ATY45_RS08905	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ATY45_RS08910	COG3734	2-keto-3-deoxy-galactonokinase
ATY45_RS08920	COG4948	Mandelate Racemase Muconate Lactonizing
ATY45_RS08925	COG0800	Aldolase
ATY45_RS08940	COG1501	Belongs to the glycosyl hydrolase 31 family
ATY45_RS08955	COG1070	Carbohydrate kinase
ATY45_RS08965	COG0477	Major facilitator Superfamily
ATY45_RS08985	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ATY45_RS09035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATY45_RS09040	COG2258	MOSC domain
ATY45_RS09045	COG3293	Transposase
ATY45_RS09055	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ATY45_RS09060	COG0505	Belongs to the CarA family
ATY45_RS09070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ATY45_RS09075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ATY45_RS09085	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ATY45_RS09130	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ATY45_RS09150	COG2205	protein histidine kinase activity
ATY45_RS09150	COG2198	Histidine kinase
ATY45_RS09150	COG0784	Response regulator, receiver
ATY45_RS09155	COG1024	Enoyl-CoA hydratase
ATY45_RS09160	COG0318	PFAM AMP-dependent synthetase and ligase
ATY45_RS09190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ATY45_RS09220	COG0840	transmembrane signaling receptor activity
ATY45_RS09240	COG3039	Transposase
ATY45_RS09260	COG0835	chemotaxis
ATY45_RS09275	COG0840	transmembrane signaling receptor activity
ATY45_RS09280	COG0840	transmembrane signaling receptor activity
ATY45_RS09285	COG0840	transmembrane signaling receptor activity
ATY45_RS09290	COG0840	transmembrane signaling receptor activity
ATY45_RS09300	COG0840	transmembrane signaling receptor activity
ATY45_RS09310	COG0840	transmembrane signaling receptor activity
ATY45_RS09330	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS09345	COG0745	RESPONSE REGULATOR receiver
ATY45_RS09355	COG0835	chemotaxis
ATY45_RS09365	COG1360	Flagellar Motor Protein
ATY45_RS09370	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ATY45_RS09390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ATY45_RS09400	COG4771	TonB-dependent receptor
ATY45_RS09445	COG3039	Transposase
ATY45_RS09460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ATY45_RS09460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ATY45_RS09465	COG1105	Belongs to the carbohydrate kinase PfkB family
ATY45_RS09470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ATY45_RS09470	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ATY45_RS09475	COG1609	Transcriptional regulator
ATY45_RS09495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ATY45_RS09500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ATY45_RS09510	COG2902	Dehydrogenase
ATY45_RS09515	COG3039	Transposase
ATY45_RS09525	COG0784	Response regulator, receiver
ATY45_RS09525	COG2205	protein histidine kinase activity
ATY45_RS09525	COG5002	protein histidine kinase activity
ATY45_RS09530	COG2733	membrane
ATY45_RS09540	COG1121	(ABC) transporter
ATY45_RS09555	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ATY45_RS09565	COG2223	nitrite transmembrane transporter activity
ATY45_RS09575	COG0243	molybdopterin cofactor binding
ATY45_RS09585	COG0477	Major facilitator Superfamily
ATY45_RS09595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATY45_RS09600	COG0174	glutamine synthetase
ATY45_RS09635	COG3842	ATPase activity
ATY45_RS09640	COG1176	ABC-type spermidine putrescine transport system, permease component I
ATY45_RS09645	COG1177	transmembrane transport
ATY45_RS09655	COG1012	belongs to the aldehyde dehydrogenase family
ATY45_RS09670	COG4535	Mg2 and Co2 transporter CorC
ATY45_RS09690	COG1702	phosphate starvation-inducible protein PhoH
ATY45_RS09720	COG0741	lytic transglycosylase activity
ATY45_RS09725	COG0723	plastoquinol--plastocyanin reductase activity
ATY45_RS09730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ATY45_RS09735	COG2857	Cytochrome c1
ATY45_RS09740	COG0625	glutathione transferase activity
ATY45_RS09745	COG2969	positive regulation of protein catabolic process
ATY45_RS09780	COG3328	transposase activity
ATY45_RS09790	COG3039	Transposase
ATY45_RS09850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ATY45_RS09870	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ATY45_RS09875	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ATY45_RS09875	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ATY45_RS09880	COG0802	atpase or kinase
ATY45_RS09885	COG0860	N-Acetylmuramoyl-L-alanine amidase
ATY45_RS09890	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ATY45_RS09910	COG1028	Short-chain dehydrogenase reductase Sdr
ATY45_RS09930	COG2081	HI0933 family
ATY45_RS09935	COG4681	YaeQ
ATY45_RS09940	COG1671	Belongs to the UPF0178 family
ATY45_RS09950	COG0625	glutathione transferase activity
ATY45_RS09960	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ATY45_RS09970	COG0513	Belongs to the DEAD box helicase family
ATY45_RS09975	COG0488	(ABC) transporter
ATY45_RS10000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ATY45_RS10005	COG0483	inositol monophosphate 1-phosphatase activity
ATY45_RS10020	COG3300	MHYT domain
ATY45_RS10020	COG5001	Diguanylate cyclase
ATY45_RS10025	COG1509	lysine 2,3-aminomutase activity
ATY45_RS10040	COG0402	S-adenosylhomocysteine deaminase activity
ATY45_RS10045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ATY45_RS10075	COG3039	Transposase
ATY45_RS10090	COG3039	Transposase
ATY45_RS10100	COG0583	DNA-binding transcription factor activity
ATY45_RS10170	COG0742	ribosomal rna small subunit methyltransferase
ATY45_RS10175	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ATY45_RS10190	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ATY45_RS10195	COG0405	Gamma-glutamyltransferase
ATY45_RS10210	COG3293	Transposase
ATY45_RS10325	COG3039	Transposase
ATY45_RS10370	COG0343	queuine tRNA-ribosyltransferase activity
ATY45_RS10375	COG1862	Preprotein translocase
ATY45_RS10380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ATY45_RS10385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ATY45_RS10415	COG3328	transposase activity
ATY45_RS10440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ATY45_RS10450	COG0704	Plays a role in the regulation of phosphate uptake
ATY45_RS10465	COG0573	inorganic phosphate transmembrane transporter activity
ATY45_RS10470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ATY45_RS10490	COG3293	Transposase
ATY45_RS10510	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ATY45_RS10520	COG1024	Enoyl-CoA hydratase
ATY45_RS10530	COG0494	nUDIX hydrolase
ATY45_RS10575	COG0116	Belongs to the methyltransferase superfamily
ATY45_RS10575	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ATY45_RS10600	COG0667	Aldo Keto reductase
ATY45_RS10610	COG2925	Exonuclease
ATY45_RS10620	COG3844	kynureninase activity
ATY45_RS10635	COG0288	reversible hydration of carbon dioxide
ATY45_RS10670	COG0316	Belongs to the HesB IscA family
ATY45_RS10675	COG0360	Binds together with S18 to 16S ribosomal RNA
ATY45_RS10685	COG0359	binds to the 23S rRNA
ATY45_RS10695	COG3115	cell septum assembly
ATY45_RS10710	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ATY45_RS10725	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ATY45_RS10735	COG2963	transposase activity
ATY45_RS10755	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ATY45_RS10765	COG2986	histidine ammonia-lyase
ATY45_RS10770	COG1228	amidohydrolase
ATY45_RS10815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ATY45_RS10825	COG1605	Chorismate mutase
ATY45_RS10825	COG0077	Prephenate dehydratase
ATY45_RS10830	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ATY45_RS10840	COG2963	transposase activity
ATY45_RS10845	COG3039	Transposase
ATY45_RS10860	COG4566	intracellular signal transduction
ATY45_RS10900	COG2963	transposase activity
ATY45_RS10915	COG0860	N-Acetylmuramoyl-L-alanine amidase
ATY45_RS10920	COG1469	GTP cyclohydrolase I activity
ATY45_RS10930	COG0617	tRNA 3'-terminal CCA addition
ATY45_RS10945	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ATY45_RS10975	COG1472	Belongs to the glycosyl hydrolase 3 family
ATY45_RS10990	COG3706	GGDEF domain
ATY45_RS10990	COG4251	negative regulation of phosphorylation
ATY45_RS10990	COG5001	Diguanylate cyclase
ATY45_RS10990	COG2203	Gaf domain
ATY45_RS11075	COG0386	Belongs to the glutathione peroxidase family
ATY45_RS11160	COG3293	Transposase
ATY45_RS11170	COG1247	-acetyltransferase
ATY45_RS11200	COG3706	GGDEF domain
ATY45_RS11220	COG3293	Transposase
ATY45_RS11230	COG1247	-acetyltransferase
ATY45_RS11255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ATY45_RS11280	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ATY45_RS11295	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ATY45_RS11305	COG0431	NADPH-dependent FMN reductase
ATY45_RS11310	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ATY45_RS11315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ATY45_RS11335	COG5002	protein histidine kinase activity
ATY45_RS11335	COG2205	protein histidine kinase activity
ATY45_RS11335	COG0784	Response regulator, receiver
ATY45_RS11360	COG3293	Transposase
ATY45_RS11375	COG0800	Aldolase
ATY45_RS11380	COG0129	dihydroxy-acid dehydratase activity
ATY45_RS11385	COG0363	glucosamine-6-phosphate deaminase activity
ATY45_RS11395	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ATY45_RS11410	COG0354	folic acid binding
ATY45_RS11420	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ATY45_RS11435	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ATY45_RS11450	COG4591	ABC-type transport system involved in lipoprotein release permease component
ATY45_RS11475	COG0811	peptide transport
ATY45_RS11490	COG1663	tetraacyldisaccharide 4'-kinase activity
ATY45_RS11500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ATY45_RS11510	COG0322	excinuclease ABC activity
ATY45_RS11560	COG2801	Transposase and inactivated derivatives
ATY45_RS11570	COG2201	protein-glutamate methylesterase activity
ATY45_RS11590	COG3293	Transposase
ATY45_RS11655	COG3293	Transposase
ATY45_RS11710	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ATY45_RS11710	COG0140	phosphoribosyl-ATP diphosphatase activity
ATY45_RS11720	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ATY45_RS11730	COG0131	Imidazoleglycerol-phosphate dehydratase
ATY45_RS11730	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ATY45_RS11745	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ATY45_RS11770	COG0124	histidyl-tRNA synthetase
ATY45_RS11775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ATY45_RS11785	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ATY45_RS11820	COG1012	belongs to the aldehyde dehydrogenase family
ATY45_RS11845	COG0697	spore germination
ATY45_RS11850	COG1794	racemase activity, acting on amino acids and derivatives
ATY45_RS11860	COG0477	Major facilitator Superfamily
ATY45_RS11870	COG0671	phosphoesterase, PA-phosphatase related
ATY45_RS11885	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ATY45_RS11900	COG2183	response to ionizing radiation
ATY45_RS11910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATY45_RS11910	COG0723	plastoquinol--plastocyanin reductase activity
ATY45_RS11925	COG3243	poly(R)-hydroxyalkanoic acid synthase
ATY45_RS11935	COG1183	phosphatidylcholine synthase activity
ATY45_RS11940	COG1028	Short-chain dehydrogenase reductase Sdr
ATY45_RS11965	COG0668	transmembrane transport
ATY45_RS11985	COG1914	H( )-stimulated, divalent metal cation uptake system
ATY45_RS12000	COG0583	DNA-binding transcription factor activity
ATY45_RS12005	COG0583	DNA-binding transcription factor activity
ATY45_RS12020	COG1028	Short-chain dehydrogenase reductase Sdr
ATY45_RS12035	COG0583	DNA-binding transcription factor activity
ATY45_RS12040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ATY45_RS12060	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ATY45_RS12095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ATY45_RS12095	COG0475	glutathione-regulated potassium exporter activity
ATY45_RS12100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ATY45_RS12110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ATY45_RS12115	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ATY45_RS12125	COG0776	regulation of translation
ATY45_RS12130	COG0539	negative regulation of cytoplasmic translation
ATY45_RS12135	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ATY45_RS12150	COG2957	Belongs to the agmatine deiminase family
ATY45_RS12160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ATY45_RS12185	COG0395	ABC-type sugar transport system, permease component
ATY45_RS12190	COG1175	transmembrane transport
ATY45_RS12220	COG2350	Protein conserved in bacteria
ATY45_RS12225	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ATY45_RS12230	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ATY45_RS12235	COG1187	pseudouridine synthase activity
ATY45_RS12260	COG0436	Aminotransferase
ATY45_RS12325	COG0277	FAD linked oxidase domain protein
ATY45_RS12330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ATY45_RS12340	COG0531	amino acid
ATY45_RS12345	COG0531	amino acid
ATY45_RS12355	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ATY45_RS12390	COG3039	Transposase
ATY45_RS12400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ATY45_RS12435	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS12490	COG0303	'Molybdopterin
ATY45_RS12500	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ATY45_RS12510	COG1426	Protein conserved in bacteria
ATY45_RS12520	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ATY45_RS12535	COG1250	3-hydroxyacyl-CoA dehydrogenase
ATY45_RS12535	COG1024	Enoyl-CoA hydratase
ATY45_RS12540	COG0183	Belongs to the thiolase family
ATY45_RS12555	COG0038	chloride channel
ATY45_RS12575	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ATY45_RS12595	COG1674	ftsk spoiiie
ATY45_RS12600	COG0492	ferredoxin-NADP+ reductase activity
ATY45_RS12630	COG0542	response to heat
ATY45_RS12670	COG5001	Diguanylate cyclase
ATY45_RS12675	COG4585	Histidine kinase
ATY45_RS12685	COG5002	protein histidine kinase activity
ATY45_RS12705	COG0835	chemotaxis
ATY45_RS12705	COG0784	Response regulator, receiver
ATY45_RS12715	COG1558	bacterial-type flagellum-dependent cell motility
ATY45_RS12720	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ATY45_RS12730	COG4787	bacterial-type flagellum-dependent cell motility
ATY45_RS12765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ATY45_RS12770	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ATY45_RS12800	COG2201	protein-glutamate methylesterase activity
ATY45_RS12820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ATY45_RS12830	COG1028	Short-chain dehydrogenase reductase Sdr
ATY45_RS12860	COG1677	Flagellar hook-basal body complex protein FliE
ATY45_RS12910	COG3190	flagellar
ATY45_RS12930	COG1684	flagellar biosynthetic protein fliR
ATY45_RS12985	COG0643	Histidine kinase
ATY45_RS12985	COG0784	Response regulator, receiver
ATY45_RS12985	COG2198	Histidine kinase
ATY45_RS13000	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS13025	COG3209	COG3209 Rhs family protein
ATY45_RS13130	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ATY45_RS13135	COG4988	ABC transporter
ATY45_RS13145	COG1271	oxidase subunit
ATY45_RS13150	COG1294	oxidase, subunit
ATY45_RS13175	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ATY45_RS13195	COG0165	Argininosuccinate lyase
ATY45_RS13210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ATY45_RS13215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATY45_RS13225	COG0137	argininosuccinate synthase activity
ATY45_RS13230	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ATY45_RS13245	COG2166	iron-sulfur cluster assembly
ATY45_RS13275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ATY45_RS13285	COG4302	ethanolamine ammonia-lyase activity
ATY45_RS13305	COG3039	Transposase
ATY45_RS13325	COG4677	pectinesterase activity
ATY45_RS13365	COG2963	transposase activity
ATY45_RS13370	COG2801	Transposase and inactivated derivatives
ATY45_RS13415	COG1278	Cold shock
ATY45_RS13430	COG3328	transposase activity
ATY45_RS13460	COG3039	Transposase
ATY45_RS13470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ATY45_RS13485	COG0557	exoribonuclease II activity
ATY45_RS13510	COG1960	acyl-CoA dehydrogenase activity
ATY45_RS13515	COG2226	methyltransferase
ATY45_RS13520	COG0646	methionine synthase
ATY45_RS13520	COG1410	methionine synthase
ATY45_RS13525	COG0646	methionine synthase
ATY45_RS13525	COG1410	methionine synthase
ATY45_RS13535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATY45_RS13545	COG1609	Transcriptional regulator
ATY45_RS13560	COG2900	Belongs to the SlyX family
ATY45_RS13575	COG0386	Belongs to the glutathione peroxidase family
ATY45_RS13580	COG1725	Transcriptional regulator
ATY45_RS13585	COG1131	(ABC) transporter
ATY45_RS13625	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS13635	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS13645	COG3293	Transposase
ATY45_RS13685	COG2850	peptidyl-arginine hydroxylation
ATY45_RS13720	COG1132	(ABC) transporter
ATY45_RS13730	COG0583	DNA-binding transcription factor activity
ATY45_RS13745	COG1605	Chorismate mutase
ATY45_RS13745	COG0287	Prephenate dehydrogenase
ATY45_RS13750	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ATY45_RS13755	COG0484	heat shock protein binding
ATY45_RS13765	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ATY45_RS13775	COG0497	DNA recombination
ATY45_RS13785	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ATY45_RS13790	COG2914	Belongs to the UPF0125 (RnfH) family
ATY45_RS13800	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ATY45_RS13820	COG1960	acyl-CoA dehydrogenase activity
ATY45_RS13830	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ATY45_RS13850	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS13870	COG3293	Transposase
ATY45_RS13885	COG2814	Major facilitator Superfamily
ATY45_RS13890	COG1566	PFAM secretion protein HlyD family protein
ATY45_RS13905	COG2207	Transcriptional regulator
ATY45_RS13930	COG4774	siderophore transport
ATY45_RS13945	COG0367	asparagine synthase
ATY45_RS13960	COG1393	Belongs to the ArsC family
ATY45_RS14020	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ATY45_RS14035	COG0233	cytoplasmic translational termination
ATY45_RS14045	COG0575	Belongs to the CDS family
ATY45_RS14055	COG0750	zinc metalloprotease
ATY45_RS14070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ATY45_RS14075	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ATY45_RS14095	COG0825	malonyl-CoA metabolic process
ATY45_RS14105	COG4771	TonB-dependent receptor
ATY45_RS14110	COG1131	(ABC) transporter
ATY45_RS14140	COG1981	membrane
ATY45_RS14180	COG0529	Catalyzes the synthesis of activated sulfate
ATY45_RS14180	COG2895	sulfate adenylyltransferase (ATP) activity
ATY45_RS14210	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ATY45_RS14225	COG2040	homocysteine
ATY45_RS14230	COG0833	amino acid
ATY45_RS14240	COG0346	lactoylglutathione lyase activity
ATY45_RS14250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATY45_RS14250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATY45_RS14260	COG2878	Part of a membrane complex involved in electron transport
ATY45_RS14280	COG1595	DNA-templated transcription, initiation
ATY45_RS14305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ATY45_RS14320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ATY45_RS14325	COG0251	oxidation-reduction process
ATY45_RS14335	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ATY45_RS14335	COG0392	lysyltransferase activity
ATY45_RS14370	COG2814	Major facilitator Superfamily
ATY45_RS14375	COG1902	pentaerythritol trinitrate reductase activity
ATY45_RS14385	COG2824	Alkylphosphonate utilization operon protein PhnA
ATY45_RS14400	COG1047	Peptidyl-prolyl cis-trans
ATY45_RS14440	COG3039	Transposase
ATY45_RS14445	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ATY45_RS14460	COG1451	nucleotide metabolic process
ATY45_RS14480	COG0183	Belongs to the thiolase family
ATY45_RS14510	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ATY45_RS14510	COG1793	dna ligase
ATY45_RS14520	COG1793	dna ligase
ATY45_RS14525	COG1201	RNA secondary structure unwinding
ATY45_RS14545	COG1278	Cold shock
ATY45_RS14550	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ATY45_RS14555	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ATY45_RS14565	COG3046	protein related to deoxyribodipyrimidine photolyase
ATY45_RS14570	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
ATY45_RS14575	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ATY45_RS14590	COG2954	triphosphatase activity
ATY45_RS14605	COG1381	Involved in DNA repair and RecF pathway recombination
ATY45_RS14635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ATY45_RS14650	COG1024	Enoyl-CoA hydratase
ATY45_RS14650	COG1250	3-hydroxyacyl-CoA dehydrogenase
ATY45_RS14670	COG1024	Enoyl-CoA hydratase
ATY45_RS14675	COG1960	acyl-CoA dehydrogenase activity
ATY45_RS14745	COG2353	YceI-like domain
ATY45_RS14755	COG2353	YceI-like domain
ATY45_RS14765	COG1760	l-serine dehydratase
ATY45_RS14775	COG0626	cystathionine gamma-synthase activity
ATY45_RS14780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ATY45_RS14785	COG0739	heme binding
ATY45_RS14795	COG1272	protein, Hemolysin III
ATY45_RS14805	COG0517	IMP dehydrogenase activity
ATY45_RS14805	COG0516	GMP reductase activity
ATY45_RS14810	COG0463	Glycosyl transferase, family 2
ATY45_RS14820	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ATY45_RS14830	COG4771	TonB-dependent receptor
ATY45_RS14835	COG1309	transcriptional regulator
ATY45_RS14845	COG1960	acyl-CoA dehydrogenase activity
ATY45_RS14875	COG0509	glycine decarboxylation via glycine cleavage system
ATY45_RS14890	COG0330	HflC and HflK could
ATY45_RS14905	COG3956	TIGRFAM MazG family protein
ATY45_RS14915	COG0494	nUDIX hydrolase
ATY45_RS14925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ATY45_RS14930	COG0837	glucose binding
ATY45_RS14945	COG1388	LysM domain
ATY45_RS14945	COG3858	chitin binding
ATY45_RS14955	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ATY45_RS14965	COG1472	Belongs to the glycosyl hydrolase 3 family
ATY45_RS15025	COG3537	Alpha-1,2-mannosidase
ATY45_RS15075	COG1446	asparaginase
ATY45_RS15085	COG2304	oxidoreductase activity
ATY45_RS15120	COG0643	Histidine kinase
ATY45_RS15120	COG0784	Response regulator, receiver
ATY45_RS15120	COG2198	Histidine kinase
ATY45_RS15125	COG0840	transmembrane signaling receptor activity
ATY45_RS15130	COG0835	chemotaxis
ATY45_RS15145	COG0189	ligase activity
ATY45_RS15155	COG1397	ADP-ribosylglycohydrolase
ATY45_RS15165	COG1199	ATP-dependent helicase activity
ATY45_RS15175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ATY45_RS15180	COG1215	transferase activity, transferring glycosyl groups
ATY45_RS15190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ATY45_RS15205	COG0535	radical SAM domain protein
ATY45_RS15210	COG0535	radical SAM domain protein
ATY45_RS15225	COG0837	glucose binding
ATY45_RS15245	COG1643	Atp-dependent helicase
ATY45_RS15250	COG0783	Belongs to the Dps family
ATY45_RS15255	COG0514	ATP-dependent DNA helicase (RecQ)
ATY45_RS15275	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ATY45_RS15290	COG3293	Transposase
ATY45_RS15305	COG0602	queuosine metabolic process
ATY45_RS15315	COG2885	chlorophyll binding
ATY45_RS15330	COG0848	biopolymer transport protein
ATY45_RS15340	COG0824	Thioesterase
ATY45_RS15345	COG2255	four-way junction helicase activity
ATY45_RS15355	COG0632	four-way junction helicase activity
ATY45_RS15445	COG2801	Transposase and inactivated derivatives
ATY45_RS15470	COG2801	Transposase and inactivated derivatives
ATY45_RS15475	COG2963	transposase activity
ATY45_RS15505	COG3328	transposase activity
ATY45_RS15515	COG3209	COG3209 Rhs family protein
ATY45_RS15535	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ATY45_RS15540	COG1845	cytochrome c oxidase, subunit III
ATY45_RS15545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ATY45_RS15560	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ATY45_RS15565	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ATY45_RS15575	COG0196	riboflavin kinase activity
ATY45_RS15580	COG0728	peptidoglycan biosynthetic process
ATY45_RS15585	COG0268	Binds directly to 16S ribosomal RNA
ATY45_RS15590	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ATY45_RS15595	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ATY45_RS15605	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ATY45_RS15610	COG0824	Thioesterase
ATY45_RS15625	COG1946	Acyl-CoA thioesterase
ATY45_RS15635	COG1595	DNA-templated transcription, initiation
ATY45_RS15650	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ATY45_RS15690	COG1877	trehalose-phosphatase activity
ATY45_RS15695	COG3387	PFAM Glycoside hydrolase 15-related
ATY45_RS15720	COG0564	pseudouridine synthase activity
ATY45_RS15725	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ATY45_RS15730	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ATY45_RS15730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ATY45_RS15740	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ATY45_RS15745	COG0045	succinate-CoA ligase (ADP-forming) activity
ATY45_RS15760	COG2184	nucleotidyltransferase activity
ATY45_RS15780	COG2194	sulfuric ester hydrolase activity
ATY45_RS15785	COG4969	Belongs to the N-Me-Phe pilin family
ATY45_RS15795	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ATY45_RS15810	COG3039	Transposase
ATY45_RS15820	COG3039	Transposase
ATY45_RS15830	COG3293	Transposase
ATY45_RS15840	COG1132	(ABC) transporter
ATY45_RS15870	COG0745	RESPONSE REGULATOR receiver
ATY45_RS15875	COG5000	phosphorelay sensor kinase activity
ATY45_RS15875	COG5002	protein histidine kinase activity
ATY45_RS15880	COG0475	glutathione-regulated potassium exporter activity
ATY45_RS15890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ATY45_RS15910	COG1187	pseudouridine synthase activity
ATY45_RS15915	COG5001	Diguanylate cyclase
ATY45_RS15915	COG5002	protein histidine kinase activity
ATY45_RS16020	COG1028	Short-chain dehydrogenase reductase Sdr
ATY45_RS16040	COG0415	Belongs to the DNA photolyase family
ATY45_RS16045	COG0305	Participates in initiation and elongation during chromosome replication
ATY45_RS16055	COG0367	asparagine synthase
ATY45_RS16080	COG1960	acyl-CoA dehydrogenase activity
ATY45_RS16095	COG0084	hydrolase, TatD family'
ATY45_RS16100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ATY45_RS16145	COG0735	belongs to the Fur family
ATY45_RS16150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ATY45_RS16185	COG3039	Transposase
ATY45_RS16205	COG3039	Transposase
ATY45_RS16230	COG2205	protein histidine kinase activity
ATY45_RS16245	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ATY45_RS16255	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ATY45_RS16265	COG0643	Histidine kinase
ATY45_RS16265	COG2198	Histidine kinase
ATY45_RS16270	COG0840	transmembrane signaling receptor activity
ATY45_RS16275	COG0835	chemotaxis
ATY45_RS16280	COG2199	diguanylate cyclase activity
ATY45_RS16280	COG2202	Pas domain
ATY45_RS16280	COG2200	EAL domain
ATY45_RS16285	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ATY45_RS16300	COG3590	peptidase
ATY45_RS16320	COG1515	deoxyribonuclease V activity
ATY45_RS16330	COG1741	Belongs to the pirin family
ATY45_RS16430	COG1741	Belongs to the pirin family
ATY45_RS16435	COG1966	Carbon starvation protein
ATY45_RS16440	COG2879	small protein
ATY45_RS16470	COG0604	alcohol dehydrogenase
ATY45_RS16470	COG3321	synthase
ATY45_RS16470	COG1028	Short-chain dehydrogenase reductase Sdr
ATY45_RS16475	COG2203	Gaf domain
ATY45_RS16475	COG3706	GGDEF domain
ATY45_RS16475	COG4251	negative regulation of phosphorylation
ATY45_RS16475	COG5001	Diguanylate cyclase
ATY45_RS16480	COG0629	single-stranded DNA binding
ATY45_RS16485	COG0142	geranyltranstransferase activity
ATY45_RS16515	COG0527	aspartate kinase activity
ATY45_RS16525	COG0384	phenazine biosynthesis protein PhzF
ATY45_RS16530	COG0384	phenazine biosynthesis protein PhzF
ATY45_RS16540	COG1764	response to oxidative stress
ATY45_RS16555	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ATY45_RS16560	COG1678	Uncharacterized ACR, COG1678
ATY45_RS16575	COG0519	Catalyzes the synthesis of GMP from XMP
ATY45_RS16580	COG3039	Transposase
ATY45_RS16605	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ATY45_RS16645	COG0693	protein deglycase activity
ATY45_RS16665	COG1959	2 iron, 2 sulfur cluster binding
ATY45_RS16670	COG0719	Fe-S assembly protein
ATY45_RS16675	COG0396	ATPase activity
ATY45_RS16680	COG0719	Fe-S assembly protein
ATY45_RS16685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ATY45_RS16695	COG2146	nitrite reductase [NAD(P)H] activity
ATY45_RS16700	COG3039	Transposase
ATY45_RS16705	COG2963	transposase activity
ATY45_RS16710	COG2801	Transposase and inactivated derivatives
ATY45_RS16725	COG3039	Transposase
ATY45_RS16750	COG0174	glutamine synthetase
ATY45_RS16755	COG3039	Transposase
ATY45_RS16760	COG3328	transposase activity
ATY45_RS16770	COG2963	transposase activity
ATY45_RS16790	COG0326	Molecular chaperone. Has ATPase activity
ATY45_RS16795	COG2207	Transcriptional regulator
ATY45_RS16820	COG0657	acetylesterase activity
ATY45_RS16820	COG2755	lipolytic protein G-D-S-L family
ATY45_RS16845	COG0488	(ABC) transporter
ATY45_RS16890	COG4651	solute:proton antiporter activity
ATY45_RS16890	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ATY45_RS16895	COG2801	Transposase and inactivated derivatives
ATY45_RS16905	COG4772	TonB-dependent receptor
ATY45_RS16915	COG4264	IucA IucC family
ATY45_RS16920	COG2814	Major facilitator Superfamily
ATY45_RS16930	COG0019	diaminopimelate decarboxylase activity
ATY45_RS16990	COG4206	TonB-dependent receptor
ATY45_RS17005	COG2963	transposase activity
ATY45_RS17020	COG0542	response to heat
ATY45_RS17065	COG0534	Mate efflux family protein
ATY45_RS17080	COG0336	Belongs to the RNA methyltransferase TrmD family
ATY45_RS17085	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ATY45_RS17090	COG0228	four-way junction DNA binding
ATY45_RS17115	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ATY45_RS17125	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ATY45_RS17180	COG1555	photosystem II stabilization
ATY45_RS17185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATY45_RS17200	COG3178	'Phosphotransferase
ATY45_RS17205	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ATY45_RS17215	COG0628	permease
ATY45_RS17225	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ATY45_RS17240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ATY45_RS17260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ATY45_RS17265	COG0271	Belongs to the BolA IbaG family
ATY45_RS17275	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ATY45_RS17285	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ATY45_RS17290	COG1137	ATPase activity
ATY45_RS17305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ATY45_RS17310	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ATY45_RS17315	COG1660	Displays ATPase and GTPase activities
ATY45_RS17325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ATY45_RS17330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ATY45_RS17335	COG2239	Acts as a magnesium transporter
ATY45_RS17345	COG1294	oxidase, subunit
ATY45_RS17350	COG1271	oxidase subunit
ATY45_RS17360	COG1113	amino acid transport
ATY45_RS17375	COG2197	response regulator
ATY45_RS17380	COG0531	amino acid
ATY45_RS17460	COG0754	glutathionylspermidine amidase activity
ATY45_RS17485	COG1842	Phage shock protein A
ATY45_RS17500	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ATY45_RS17505	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ATY45_RS17515	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ATY45_RS17550	COG2201	protein-glutamate methylesterase activity
ATY45_RS17580	COG2201	protein-glutamate methylesterase activity
ATY45_RS17615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ATY45_RS17635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ATY45_RS17670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ATY45_RS17675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ATY45_RS17710	COG3039	Transposase
ATY45_RS17730	COG0745	RESPONSE REGULATOR receiver
ATY45_RS17735	COG2205	protein histidine kinase activity
ATY45_RS17750	COG3293	Transposase
ATY45_RS17755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ATY45_RS17800	COG3453	Protein conserved in bacteria
ATY45_RS17800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ATY45_RS17805	COG0725	ABC transporter, periplasmic molybdate-binding protein
ATY45_RS17810	COG4149	molybdate abc transporter
ATY45_RS17815	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ATY45_RS17835	COG0642	Histidine kinase
ATY45_RS17850	COG1028	Short-chain dehydrogenase reductase Sdr
ATY45_RS17860	COG1022	Amp-dependent synthetase and ligase
ATY45_RS17885	COG1376	ErfK ybiS ycfS ynhG family protein
ATY45_RS17890	COG0739	heme binding
ATY45_RS17895	COG4773	Receptor
ATY45_RS17900	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ATY45_RS17905	COG1301	dicarboxylic acid transport
ATY45_RS17925	COG2304	oxidoreductase activity
ATY45_RS17945	COG0714	Associated with various cellular activities
ATY45_RS17995	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ATY45_RS18025	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ATY45_RS18035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ATY45_RS18060	COG1561	YicC-like family, N-terminal region
ATY45_RS18065	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ATY45_RS18080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ATY45_RS18110	COG0006	proline dipeptidase activity
ATY45_RS18135	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ATY45_RS18145	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ATY45_RS18155	COG2912	Transglutaminase-like superfamily
ATY45_RS18160	COG1773	rubredoxin
ATY45_RS18165	COG0352	thiamine-phosphate diphosphorylase activity
ATY45_RS18185	COG2801	Transposase and inactivated derivatives
ATY45_RS18190	COG2963	transposase activity
ATY45_RS18200	COG0281	malic enzyme
ATY45_RS18200	COG0280	phosphate acetyltransferase
ATY45_RS18220	COG4191	Histidine kinase
ATY45_RS18235	COG0583	DNA-binding transcription factor activity
ATY45_RS18250	COG2197	response regulator
ATY45_RS18260	COG0642	Histidine kinase
ATY45_RS18275	COG2851	Citrate transporter
ATY45_RS18280	COG1028	Short-chain dehydrogenase reductase Sdr
ATY45_RS18285	COG1609	Transcriptional regulator
ATY45_RS18320	COG1162	GTPase activity
ATY45_RS18345	COG0726	polysaccharide deacetylase
ATY45_RS18350	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ATY45_RS18395	COG0242	peptide deformylase activity
ATY45_RS18415	COG0714	Associated with various cellular activities
ATY45_RS18435	COG0537	adenosine 5'-monophosphoramidase activity
ATY45_RS18465	COG0314	molybdopterin synthase activity
ATY45_RS18470	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ATY45_RS18475	COG0315	cyclic pyranopterin monophosphate synthase activity
ATY45_RS18485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ATY45_RS18490	COG1234	tRNA 3'-trailer cleavage
ATY45_RS18495	COG3642	lipopolysaccharide core region biosynthetic process
ATY45_RS18500	COG0859	PFAM glycosyl transferase family 9
ATY45_RS18510	COG0582	viral genome integration into host DNA
ATY45_RS18580	COG0631	protein serine/threonine phosphatase activity
ATY45_RS18590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ATY45_RS18615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ATY45_RS18655	COG0544	peptidyl-prolyl cis-trans isomerase activity
ATY45_RS18680	COG2963	transposase activity
ATY45_RS18710	COG0473	3-isopropylmalate dehydrogenase activity
ATY45_RS18740	COG4783	chaperone-mediated protein folding
ATY45_RS18755	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ATY45_RS18765	COG0438	transferase activity, transferring glycosyl groups
ATY45_RS18770	COG0671	phosphoesterase, PA-phosphatase related
ATY45_RS18775	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ATY45_RS18795	COG2833	Protein of unknown function (DUF455)
ATY45_RS18815	COG0285	dihydrofolate synthase activity
ATY45_RS18825	COG0406	alpha-ribazole phosphatase activity
ATY45_RS18855	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ATY45_RS18860	COG4208	sulfate ABC transporter
ATY45_RS18865	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ATY45_RS18870	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ATY45_RS18875	COG0156	8-amino-7-oxononanoate synthase activity
ATY45_RS18900	COG0604	alcohol dehydrogenase
ATY45_RS18905	COG0446	pyridine nucleotide-disulphide oxidoreductase
ATY45_RS18905	COG1902	pentaerythritol trinitrate reductase activity
ATY45_RS18915	COG3293	Transposase
ATY45_RS18945	COG0584	glycerophosphoryl diester phosphodiesterase
ATY45_RS18955	COG3293	Transposase
ATY45_RS18975	COG3039	Transposase
ATY45_RS18990	COG0625	glutathione transferase activity
ATY45_RS19000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ATY45_RS19005	COG1217	gtp-binding protein TYPA
ATY45_RS19025	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ATY45_RS19095	COG2963	transposase activity
ATY45_RS19125	COG3293	Transposase
ATY45_RS19150	COG3293	Transposase
ATY45_RS19175	COG3781	membrane
ATY45_RS19185	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ATY45_RS19225	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ATY45_RS19260	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ATY45_RS19270	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ATY45_RS19305	COG0066	3-isopropylmalate dehydratase activity
ATY45_RS19310	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ATY45_RS19345	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ATY45_RS19350	COG1538	Outer membrane efflux protein
ATY45_RS19355	COG1519	Transferase
ATY45_RS19360	COG1560	Kdo2-lipid A biosynthetic process
ATY45_RS19400	COG0308	aminopeptidase N
ATY45_RS19405	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ATY45_RS19415	COG0330	HflC and HflK could
ATY45_RS19420	COG0330	HflC and HflK could
ATY45_RS19440	COG0678	peroxiredoxin activity
ATY45_RS19450	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS19500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ATY45_RS19515	COG3829	transcription factor binding
ATY45_RS19540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ATY45_RS19545	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ATY45_RS19555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ATY45_RS19560	COG1028	Short-chain dehydrogenase reductase Sdr
ATY45_RS19585	COG1399	metal-binding, possibly nucleic acid-binding protein
ATY45_RS19625	COG1518	maintenance of DNA repeat elements
ATY45_RS19630	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ATY45_RS19670	COG2188	Transcriptional regulator
ATY45_RS19685	COG1450	Type ii and iii secretion system protein
ATY45_RS19700	COG3166	PFAM Fimbrial assembly family protein
ATY45_RS19705	COG3156	type II secretion system protein K
ATY45_RS19710	COG4795	General secretion pathway protein
ATY45_RS19715	COG2165	general secretion pathway protein
ATY45_RS19720	COG4970	Tfp pilus assembly protein FimT
ATY45_RS19725	COG2165	general secretion pathway protein
ATY45_RS19730	COG1459	type II secretion system
ATY45_RS19740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ATY45_RS19750	COG5295	Hep Hag repeat protein
ATY45_RS19755	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ATY45_RS19755	COG0047	phosphoribosylformylglycinamidine synthase activity
ATY45_RS19760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ATY45_RS19765	COG4974	Belongs to the 'phage' integrase family
ATY45_RS19780	COG0795	lipopolysaccharide-transporting ATPase activity
ATY45_RS19790	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ATY45_RS19805	COG0525	valine-tRNA ligase activity
ATY45_RS19815	COG2963	transposase activity
ATY45_RS19820	COG2801	Transposase and inactivated derivatives
ATY45_RS19830	COG3039	Transposase
ATY45_RS19855	COG3039	Transposase
ATY45_RS19880	COG1183	phosphatidylcholine synthase activity
ATY45_RS19890	COG0442	prolyl-tRNA aminoacylation
ATY45_RS19905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ATY45_RS19910	COG1127	ABC transporter
ATY45_RS19915	COG3218	ABC-type transport auxiliary lipoprotein component
ATY45_RS19915	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ATY45_RS19950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATY45_RS19955	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ATY45_RS19955	COG0662	Cupin 2, conserved barrel domain protein
ATY45_RS19980	COG2086	electron transfer activity
ATY45_RS20005	COG3328	transposase activity
ATY45_RS20045	COG0626	cystathionine gamma-synthase activity
ATY45_RS20085	COG0513	Belongs to the DEAD box helicase family
ATY45_RS20095	COG0720	synthase
ATY45_RS20105	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ATY45_RS20110	COG1956	GAF domain-containing protein
ATY45_RS20145	COG0339	signal peptide processing
ATY45_RS20190	COG3293	Transposase
ATY45_RS20205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ATY45_RS20210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ATY45_RS20215	COG3842	ATPase activity
ATY45_RS20265	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ATY45_RS20270	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ATY45_RS20275	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ATY45_RS20280	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ATY45_RS20290	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ATY45_RS20300	COG0356	it plays a direct role in the translocation of protons across the membrane
ATY45_RS20320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ATY45_RS20330	COG0508	dehydrogenase complex catalyzes the overall conversion of
ATY45_RS20360	COG2011	ABC-type metal ion transport system permease component
ATY45_RS20370	COG0697	spore germination
ATY45_RS20405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ATY45_RS20410	COG1187	pseudouridine synthase activity
ATY45_RS20415	COG2813	Specifically methylates the guanine in position
ATY45_RS20445	COG2202	Pas domain
ATY45_RS20445	COG2205	protein histidine kinase activity
ATY45_RS20470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATY45_RS20520	COG0745	RESPONSE REGULATOR receiver
ATY45_RS20535	COG1404	Belongs to the peptidase S8 family
ATY45_RS20555	COG0842	Transport permease protein
ATY45_RS20560	COG1131	(ABC) transporter
ATY45_RS20565	COG0025	NhaP-type Na H and K H
ATY45_RS20580	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ATY45_RS20590	COG1573	uracil-dna glycosylase
ATY45_RS20600	COG3384	dioxygenase
ATY45_RS20615	COG0667	Aldo Keto reductase
ATY45_RS20630	COG3590	peptidase
ATY45_RS20650	COG0531	amino acid
ATY45_RS20660	COG3279	Response regulator of the LytR AlgR family
ATY45_RS20665	COG3279	Response regulator of the LytR AlgR family
ATY45_RS20670	COG2972	Histidine kinase
ATY45_RS20705	COG1271	oxidase subunit
ATY45_RS20710	COG1294	oxidase, subunit
ATY45_RS20720	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS20735	COG3039	Transposase
ATY45_RS20795	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ATY45_RS20805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ATY45_RS20820	COG2963	transposase activity
ATY45_RS20860	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ATY45_RS20865	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ATY45_RS20870	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ATY45_RS20880	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ATY45_RS20885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ATY45_RS20900	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ATY45_RS20925	COG2963	transposase activity
ATY45_RS21070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ATY45_RS21080	COG1560	Kdo2-lipid A biosynthetic process
ATY45_RS21130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ATY45_RS21130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ATY45_RS21135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ATY45_RS21140	COG0242	peptide deformylase activity
ATY45_RS21145	COG1652	LysM domain
ATY45_RS21150	COG0758	DNA mediated transformation
ATY45_RS21155	COG2922	Belongs to the Smg family
ATY45_RS21170	COG1754	DNA topoisomerase type I activity
ATY45_RS21170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ATY45_RS21175	COG0009	L-threonylcarbamoyladenylate synthase
ATY45_RS21190	COG1028	Short-chain dehydrogenase reductase Sdr
ATY45_RS21200	COG0616	signal peptide processing
ATY45_RS21205	COG0534	Mate efflux family protein
ATY45_RS21225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ATY45_RS21250	COG1324	tolerance protein
ATY45_RS21265	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ATY45_RS21270	COG0511	ligase activity, forming carbon-carbon bonds
ATY45_RS21280	COG0439	Biotin carboxylase
ATY45_RS21320	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ATY45_RS21370	COG3210	domain, Protein
ATY45_RS21375	COG2831	hemolysin activation secretion protein
ATY45_RS21400	COG0671	phosphoesterase, PA-phosphatase related
ATY45_RS21400	COG2453	phosphatase
ATY45_RS21405	COG2267	carboxylic ester hydrolase activity
ATY45_RS21415	COG2267	carboxylic ester hydrolase activity
ATY45_RS21420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ATY45_RS21435	COG0151	Belongs to the GarS family
ATY45_RS21440	COG1136	(ABC) transporter
ATY45_RS21440	COG0577	efflux transmembrane transporter activity
ATY45_RS21450	COG1289	transmembrane transporter activity
ATY45_RS21465	COG2814	Major facilitator Superfamily
ATY45_RS21485	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ATY45_RS21510	COG3293	Transposase
ATY45_RS21535	COG0745	RESPONSE REGULATOR receiver
ATY45_RS21545	COG2963	transposase activity
ATY45_RS21585	COG0739	heme binding
ATY45_RS21600	COG2211	Major facilitator Superfamily
ATY45_RS21605	COG0708	Exodeoxyribonuclease III
ATY45_RS21620	COG1192	Involved in chromosome partitioning
ATY45_RS21625	COG1475	DNA binding
ATY45_RS21640	COG0463	Glycosyl transferase, family 2
ATY45_RS21665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ATY45_RS21690	COG4221	oxidoreductase activity
ATY45_RS21695	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS21705	COG1414	Transcriptional regulator
ATY45_RS21715	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ATY45_RS21720	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ATY45_RS21725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ATY45_RS21735	COG3485	protocatechuate 3,4-dioxygenase
ATY45_RS21740	COG3485	protocatechuate 3,4-dioxygenase
ATY45_RS21750	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ATY45_RS21760	COG2963	transposase activity
ATY45_RS21785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ATY45_RS21790	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ATY45_RS21800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ATY45_RS21800	COG0045	succinate-CoA ligase (ADP-forming) activity
ATY45_RS21800	COG1042	CoA-binding domain protein
ATY45_RS21810	COG2239	Acts as a magnesium transporter
ATY45_RS21830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ATY45_RS21835	COG3387	PFAM Glycoside hydrolase 15-related
ATY45_RS21850	COG3100	YcgL domain-containing protein
ATY45_RS21855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ATY45_RS21865	COG0463	Glycosyl transferase, family 2
ATY45_RS21880	COG1028	Short-chain dehydrogenase reductase Sdr
ATY45_RS21890	COG0156	8-amino-7-oxononanoate synthase activity
ATY45_RS21895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ATY45_RS21900	COG1040	competence protein
ATY45_RS21905	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ATY45_RS21915	COG0628	permease
ATY45_RS21925	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ATY45_RS21935	COG1595	DNA-templated transcription, initiation
ATY45_RS21940	COG0753	catalase activity
ATY45_RS21990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ATY45_RS21995	COG0180	Tryptophanyl-tRNA synthetase
ATY45_RS22000	COG3237	CsbD-like
ATY45_RS22035	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ATY45_RS22050	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ATY45_RS22055	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ATY45_RS22055	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ATY45_RS22095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ATY45_RS22120	COG1566	PFAM secretion protein HlyD family protein
ATY45_RS22140	COG1199	ATP-dependent helicase activity
ATY45_RS22175	COG0583	DNA-binding transcription factor activity
ATY45_RS22220	COG0625	glutathione transferase activity
ATY45_RS22255	COG4555	ABC transporter
ATY45_RS22265	COG1476	TRANSCRIPTIONal
ATY45_RS22285	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ATY45_RS22290	COG1131	(ABC) transporter
ATY45_RS22295	COG0842	Transport permease protein
ATY45_RS22350	COG2801	Transposase and inactivated derivatives
ATY45_RS22355	COG3293	Transposase
ATY45_RS22390	COG1181	Belongs to the D-alanine--D-alanine ligase family
ATY45_RS22405	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ATY45_RS22415	COG0564	pseudouridine synthase activity
ATY45_RS22435	COG0339	signal peptide processing
ATY45_RS22455	COG3293	Transposase
ATY45_RS22470	COG3254	rhamnose metabolic process
ATY45_RS22475	COG0738	Major facilitator superfamily
ATY45_RS22480	COG1414	Transcriptional regulator
ATY45_RS22490	COG3293	Transposase
ATY45_RS22500	COG2205	protein histidine kinase activity
ATY45_RS22515	COG3459	Glycosyltransferase 36 associated
ATY45_RS22520	COG2211	Major facilitator Superfamily
ATY45_RS22525	COG3265	gluconokinase activity
ATY45_RS22530	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ATY45_RS22550	COG2963	transposase activity
ATY45_RS22555	COG2801	Transposase and inactivated derivatives
ATY45_RS22580	COG3039	Transposase
ATY45_RS22635	COG1127	ABC transporter
ATY45_RS22640	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ATY45_RS22645	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ATY45_RS22660	COG2853	Lipoprotein
ATY45_RS22680	COG3293	Transposase
ATY45_RS22690	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ATY45_RS22700	COG2963	transposase activity
ATY45_RS22735	COG3135	benzoate transporter
ATY45_RS22740	COG3135	benzoate transporter
ATY45_RS22760	COG0676	glucose-6-phosphate 1-epimerase activity
ATY45_RS22785	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ATY45_RS22795	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ATY45_RS22800	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ATY45_RS22805	COG1064	alcohol dehydrogenase
ATY45_RS22845	COG2826	transposase and inactivated derivatives, IS30 family
ATY45_RS22850	COG4773	Receptor
ATY45_RS22875	COG1522	sequence-specific DNA binding
ATY45_RS22880	COG3186	Phenylalanine-4-hydroxylase
ATY45_RS22890	COG2755	lipolytic protein G-D-S-L family
ATY45_RS22905	COG2963	transposase activity
ATY45_RS22920	COG0656	L-ascorbic acid biosynthetic process
ATY45_RS22925	COG2130	NADP-dependent
ATY45_RS22930	COG0667	Aldo Keto reductase
ATY45_RS22940	COG1187	pseudouridine synthase activity
ATY45_RS22955	COG1643	Atp-dependent helicase
ATY45_RS22960	COG4807	Protein conserved in bacteria
ATY45_RS22965	COG4948	Mandelate Racemase Muconate Lactonizing
ATY45_RS22970	COG0179	Fumarylacetoacetate (FAA) hydrolase
ATY45_RS22975	COG1028	Short-chain dehydrogenase reductase Sdr
ATY45_RS22995	COG3507	Belongs to the glycosyl hydrolase 43 family
ATY45_RS23040	COG3162	membrane
ATY45_RS23045	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ATY45_RS23060	COG0708	Exodeoxyribonuclease III
ATY45_RS23075	COG2091	lysine biosynthetic process via aminoadipic acid
ATY45_RS23085	COG3540	Alkaline phosphatase
ATY45_RS23090	COG0357	Ribosomal RNA small subunit methyltransferase G
ATY45_RS23115	COG2159	amidohydrolase
ATY45_RS23130	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ATY45_RS23135	COG0583	DNA-binding transcription factor activity
ATY45_RS23140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ATY45_RS23155	COG0210	DNA helicase
ATY45_RS23170	COG0531	amino acid
ATY45_RS23175	COG1322	Protein conserved in bacteria
ATY45_RS23185	COG0386	Belongs to the glutathione peroxidase family
ATY45_RS23200	COG3293	Transposase
ATY45_RS23240	COG0793	Belongs to the peptidase S41A family
ATY45_RS23245	COG4942	peptidase
ATY45_RS23255	COG2234	aminopeptidase activity
ATY45_RS23300	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ATY45_RS23305	COG0302	gtp cyclohydrolase
ATY45_RS23325	COG0477	Major facilitator Superfamily
ATY45_RS23405	COG1929	Belongs to the glycerate kinase type-1 family
ATY45_RS23410	COG2271	Major facilitator Superfamily
ATY45_RS23425	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ATY45_RS23430	COG0861	Integral membrane protein TerC family
ATY45_RS23440	COG0584	glycerophosphoryl diester phosphodiesterase
ATY45_RS23450	COG0671	phosphoesterase, PA-phosphatase related
ATY45_RS23460	COG0726	polysaccharide deacetylase