locus-tag	class	description
ATY46_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ATY46_RS00020	COG0187	DNA topoisomerase II activity
ATY46_RS00030	COG0501	Belongs to the peptidase M48B family
ATY46_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ATY46_RS00080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ATY46_RS00090	COG4772	TonB-dependent receptor
ATY46_RS00105	COG3039	Transposase
ATY46_RS00110	COG1304	FMN binding
ATY46_RS00115	COG1755	Isoprenylcysteine carboxyl methyltransferase
ATY46_RS00135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATY46_RS00150	COG3039	Transposase
ATY46_RS00160	COG1116	anion transmembrane transporter activity
ATY46_RS00180	COG0508	dehydrogenase complex catalyzes the overall conversion of
ATY46_RS00200	COG3039	Transposase
ATY46_RS00210	COG0513	Belongs to the DEAD box helicase family
ATY46_RS00245	COG3039	Transposase
ATY46_RS00300	COG1858	cytochrome C peroxidase
ATY46_RS00310	COG0702	epimerase
ATY46_RS00335	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ATY46_RS00355	COG1649	PFAM Uncharacterised BCR, COG1649
ATY46_RS00360	COG2354	Protein conserved in bacteria
ATY46_RS00365	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ATY46_RS00375	COG3293	Transposase
ATY46_RS00385	COG1511	domain protein
ATY46_RS00385	COG3264	Mechanosensitive ion channel
ATY46_RS00465	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ATY46_RS00570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ATY46_RS00580	COG0642	Histidine kinase
ATY46_RS00585	COG1090	epimerase
ATY46_RS00595	COG3039	Transposase
ATY46_RS00620	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS00675	COG1136	(ABC) transporter
ATY46_RS00690	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS00715	COG1272	protein, Hemolysin III
ATY46_RS00720	COG1111	helicase
ATY46_RS00720	COG1205	dead DEAH box helicase
ATY46_RS00775	COG0069	glutamate synthase activity
ATY46_RS00775	COG0067	glutamate synthase
ATY46_RS00775	COG0070	glutamate synthase
ATY46_RS00780	COG0493	'glutamate synthase
ATY46_RS00800	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS00825	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ATY46_RS00830	COG1609	Transcriptional regulator
ATY46_RS00855	COG0366	Alpha amylase catalytic
ATY46_RS00860	COG0366	Alpha amylase catalytic
ATY46_RS00865	COG2801	Transposase and inactivated derivatives
ATY46_RS00880	COG3328	transposase activity
ATY46_RS00910	COG0606	chelatase, subunit chli
ATY46_RS00945	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ATY46_RS00950	COG1166	arginine decarboxylase activity
ATY46_RS01015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ATY46_RS01040	COG1028	Short-chain dehydrogenase reductase Sdr
ATY46_RS01055	COG2801	Transposase and inactivated derivatives
ATY46_RS01065	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ATY46_RS01080	COG0210	DNA helicase
ATY46_RS01095	COG3132	Protein of unknown function, DUF480
ATY46_RS01100	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ATY46_RS01105	COG0284	orotidine-5'-phosphate decarboxylase activity
ATY46_RS01135	COG2937	Belongs to the GPAT DAPAT family
ATY46_RS01155	COG2963	transposase activity
ATY46_RS01170	COG2755	lipolytic protein G-D-S-L family
ATY46_RS01180	COG3186	Phenylalanine-4-hydroxylase
ATY46_RS01185	COG1522	sequence-specific DNA binding
ATY46_RS01200	COG4773	Receptor
ATY46_RS01205	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS01240	COG1064	alcohol dehydrogenase
ATY46_RS01245	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ATY46_RS01250	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ATY46_RS01260	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ATY46_RS01265	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS01290	COG3039	Transposase
ATY46_RS01295	COG0676	glucose-6-phosphate 1-epimerase activity
ATY46_RS01315	COG3135	benzoate transporter
ATY46_RS01320	COG3135	benzoate transporter
ATY46_RS01355	COG2963	transposase activity
ATY46_RS01365	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ATY46_RS01375	COG3293	Transposase
ATY46_RS01410	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ATY46_RS01415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ATY46_RS01420	COG1127	ABC transporter
ATY46_RS01450	COG3293	Transposase
ATY46_RS01480	COG2801	Transposase and inactivated derivatives
ATY46_RS01485	COG2963	transposase activity
ATY46_RS01505	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ATY46_RS01510	COG3293	Transposase
ATY46_RS01520	COG3265	gluconokinase activity
ATY46_RS01525	COG2211	Major facilitator Superfamily
ATY46_RS01530	COG3459	Glycosyltransferase 36 associated
ATY46_RS01545	COG2205	protein histidine kinase activity
ATY46_RS01555	COG1414	Transcriptional regulator
ATY46_RS01560	COG0738	Major facilitator superfamily
ATY46_RS01565	COG3254	rhamnose metabolic process
ATY46_RS01590	COG0339	signal peptide processing
ATY46_RS01615	COG0564	pseudouridine synthase activity
ATY46_RS01625	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ATY46_RS01640	COG1181	Belongs to the D-alanine--D-alanine ligase family
ATY46_RS01675	COG3293	Transposase
ATY46_RS01680	COG2963	transposase activity
ATY46_RS01725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ATY46_RS01735	COG0842	Transport permease protein
ATY46_RS01740	COG1131	(ABC) transporter
ATY46_RS01745	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ATY46_RS01765	COG1476	TRANSCRIPTIONal
ATY46_RS01775	COG4555	ABC transporter
ATY46_RS01810	COG0625	glutathione transferase activity
ATY46_RS01855	COG0583	DNA-binding transcription factor activity
ATY46_RS01890	COG1199	ATP-dependent helicase activity
ATY46_RS01910	COG1566	PFAM secretion protein HlyD family protein
ATY46_RS01935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ATY46_RS01975	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ATY46_RS01975	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ATY46_RS01980	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ATY46_RS01995	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ATY46_RS02030	COG3237	CsbD-like
ATY46_RS02035	COG0180	Tryptophanyl-tRNA synthetase
ATY46_RS02040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ATY46_RS02090	COG0753	catalase activity
ATY46_RS02095	COG1595	DNA-templated transcription, initiation
ATY46_RS02105	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ATY46_RS02115	COG0628	permease
ATY46_RS02125	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ATY46_RS02130	COG1040	competence protein
ATY46_RS02135	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ATY46_RS02140	COG0156	8-amino-7-oxononanoate synthase activity
ATY46_RS02150	COG1028	Short-chain dehydrogenase reductase Sdr
ATY46_RS02165	COG0463	Glycosyl transferase, family 2
ATY46_RS02175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ATY46_RS02180	COG3100	YcgL domain-containing protein
ATY46_RS02195	COG3387	PFAM Glycoside hydrolase 15-related
ATY46_RS02200	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ATY46_RS02215	COG2239	Acts as a magnesium transporter
ATY46_RS02225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ATY46_RS02225	COG1042	CoA-binding domain protein
ATY46_RS02225	COG0045	succinate-CoA ligase (ADP-forming) activity
ATY46_RS02235	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ATY46_RS02240	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ATY46_RS02260	COG2963	transposase activity
ATY46_RS02270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ATY46_RS02280	COG3485	protocatechuate 3,4-dioxygenase
ATY46_RS02285	COG3485	protocatechuate 3,4-dioxygenase
ATY46_RS02295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ATY46_RS02300	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ATY46_RS02305	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ATY46_RS02315	COG1414	Transcriptional regulator
ATY46_RS02325	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS02330	COG4221	oxidoreductase activity
ATY46_RS02345	COG0018	arginyl-trna synthetase
ATY46_RS02350	COG2003	Belongs to the UPF0758 family
ATY46_RS02380	COG0463	Glycosyl transferase, family 2
ATY46_RS02395	COG1475	DNA binding
ATY46_RS02400	COG1192	Involved in chromosome partitioning
ATY46_RS02415	COG0708	Exodeoxyribonuclease III
ATY46_RS02420	COG2211	Major facilitator Superfamily
ATY46_RS02435	COG0739	heme binding
ATY46_RS02475	COG2963	transposase activity
ATY46_RS02485	COG0745	RESPONSE REGULATOR receiver
ATY46_RS02510	COG3293	Transposase
ATY46_RS02535	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ATY46_RS02555	COG2814	Major facilitator Superfamily
ATY46_RS02570	COG1289	transmembrane transporter activity
ATY46_RS02580	COG1136	(ABC) transporter
ATY46_RS02580	COG0577	efflux transmembrane transporter activity
ATY46_RS02585	COG0151	Belongs to the GarS family
ATY46_RS02600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ATY46_RS02605	COG2267	carboxylic ester hydrolase activity
ATY46_RS02615	COG2267	carboxylic ester hydrolase activity
ATY46_RS02620	COG0671	phosphoesterase, PA-phosphatase related
ATY46_RS02620	COG2453	phosphatase
ATY46_RS02630	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ATY46_RS02670	COG0439	Biotin carboxylase
ATY46_RS02680	COG0511	ligase activity, forming carbon-carbon bonds
ATY46_RS02685	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ATY46_RS02700	COG1324	tolerance protein
ATY46_RS02725	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ATY46_RS02750	COG0534	Mate efflux family protein
ATY46_RS02755	COG0616	signal peptide processing
ATY46_RS02765	COG1028	Short-chain dehydrogenase reductase Sdr
ATY46_RS02780	COG0009	L-threonylcarbamoyladenylate synthase
ATY46_RS02785	COG1754	DNA topoisomerase type I activity
ATY46_RS02785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ATY46_RS02800	COG2922	Belongs to the Smg family
ATY46_RS02805	COG0758	DNA mediated transformation
ATY46_RS02810	COG1652	LysM domain
ATY46_RS02815	COG0242	peptide deformylase activity
ATY46_RS02820	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ATY46_RS02825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ATY46_RS02825	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ATY46_RS02875	COG1560	Kdo2-lipid A biosynthetic process
ATY46_RS02885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ATY46_RS03085	COG1063	alcohol dehydrogenase
ATY46_RS03100	COG1294	oxidase, subunit
ATY46_RS03105	COG1271	oxidase subunit
ATY46_RS03110	COG2204	response regulator
ATY46_RS03145	COG2972	Histidine kinase
ATY46_RS03150	COG3279	Response regulator of the LytR AlgR family
ATY46_RS03155	COG3279	Response regulator of the LytR AlgR family
ATY46_RS03165	COG0531	amino acid
ATY46_RS03200	COG0667	Aldo Keto reductase
ATY46_RS03215	COG3384	dioxygenase
ATY46_RS03225	COG1573	uracil-dna glycosylase
ATY46_RS03235	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ATY46_RS03250	COG0025	NhaP-type Na H and K H
ATY46_RS03255	COG1131	(ABC) transporter
ATY46_RS03260	COG0842	Transport permease protein
ATY46_RS03280	COG1404	Belongs to the peptidase S8 family
ATY46_RS03295	COG0745	RESPONSE REGULATOR receiver
ATY46_RS03345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATY46_RS03370	COG2205	protein histidine kinase activity
ATY46_RS03370	COG2202	Pas domain
ATY46_RS03405	COG2813	Specifically methylates the guanine in position
ATY46_RS03410	COG1187	pseudouridine synthase activity
ATY46_RS03415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ATY46_RS03450	COG0697	spore germination
ATY46_RS03460	COG2011	ABC-type metal ion transport system permease component
ATY46_RS03490	COG0508	dehydrogenase complex catalyzes the overall conversion of
ATY46_RS03500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ATY46_RS03520	COG0356	it plays a direct role in the translocation of protons across the membrane
ATY46_RS03530	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ATY46_RS03540	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ATY46_RS03545	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ATY46_RS03550	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ATY46_RS03555	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ATY46_RS03605	COG3842	ATPase activity
ATY46_RS03610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ATY46_RS03615	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ATY46_RS03630	COG3293	Transposase
ATY46_RS03675	COG0339	signal peptide processing
ATY46_RS03710	COG1956	GAF domain-containing protein
ATY46_RS03715	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ATY46_RS03725	COG0720	synthase
ATY46_RS03735	COG0513	Belongs to the DEAD box helicase family
ATY46_RS03775	COG0626	cystathionine gamma-synthase activity
ATY46_RS03815	COG3328	transposase activity
ATY46_RS03840	COG2086	electron transfer activity
ATY46_RS03865	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ATY46_RS03865	COG0662	Cupin 2, conserved barrel domain protein
ATY46_RS03870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATY46_RS03905	COG3218	ABC-type transport auxiliary lipoprotein component
ATY46_RS03905	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ATY46_RS03910	COG1127	ABC transporter
ATY46_RS03915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ATY46_RS03930	COG0442	prolyl-tRNA aminoacylation
ATY46_RS03940	COG1183	phosphatidylcholine synthase activity
ATY46_RS03965	COG3039	Transposase
ATY46_RS04005	COG2801	Transposase and inactivated derivatives
ATY46_RS04010	COG2963	transposase activity
ATY46_RS04020	COG0525	valine-tRNA ligase activity
ATY46_RS04035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ATY46_RS04045	COG0795	lipopolysaccharide-transporting ATPase activity
ATY46_RS04055	COG4974	Belongs to the 'phage' integrase family
ATY46_RS04060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ATY46_RS04065	COG0047	phosphoribosylformylglycinamidine synthase activity
ATY46_RS04065	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ATY46_RS04070	COG5295	Hep Hag repeat protein
ATY46_RS04090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ATY46_RS04100	COG1459	type II secretion system
ATY46_RS04105	COG2165	general secretion pathway protein
ATY46_RS04110	COG4970	Tfp pilus assembly protein FimT
ATY46_RS04115	COG2165	general secretion pathway protein
ATY46_RS04120	COG4795	General secretion pathway protein
ATY46_RS04125	COG3156	type II secretion system protein K
ATY46_RS04130	COG3166	PFAM Fimbrial assembly family protein
ATY46_RS04145	COG1450	Type ii and iii secretion system protein
ATY46_RS04160	COG2188	Transcriptional regulator
ATY46_RS04200	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ATY46_RS04205	COG1518	maintenance of DNA repeat elements
ATY46_RS04245	COG1399	metal-binding, possibly nucleic acid-binding protein
ATY46_RS04270	COG1028	Short-chain dehydrogenase reductase Sdr
ATY46_RS04275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ATY46_RS04285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ATY46_RS04290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ATY46_RS04315	COG3829	transcription factor binding
ATY46_RS04340	COG3039	Transposase
ATY46_RS04385	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS04395	COG0678	peroxiredoxin activity
ATY46_RS04415	COG0330	HflC and HflK could
ATY46_RS04420	COG0330	HflC and HflK could
ATY46_RS04435	COG0308	aminopeptidase N
ATY46_RS04460	COG3039	Transposase
ATY46_RS04480	COG1560	Kdo2-lipid A biosynthetic process
ATY46_RS04485	COG1519	Transferase
ATY46_RS04490	COG1538	Outer membrane efflux protein
ATY46_RS04495	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ATY46_RS04525	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ATY46_RS04530	COG0066	3-isopropylmalate dehydratase activity
ATY46_RS04565	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ATY46_RS04575	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ATY46_RS04580	COG3710	Transcriptional regulator
ATY46_RS04605	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ATY46_RS04645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ATY46_RS04655	COG3781	membrane
ATY46_RS04670	COG0625	glutathione transferase activity
ATY46_RS04680	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ATY46_RS04685	COG1217	gtp-binding protein TYPA
ATY46_RS04705	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ATY46_RS04725	COG2963	transposase activity
ATY46_RS04730	COG2801	Transposase and inactivated derivatives
ATY46_RS04775	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS04805	COG2963	transposase activity
ATY46_RS04835	COG3293	Transposase
ATY46_RS04855	COG3039	Transposase
ATY46_RS04875	COG3293	Transposase
ATY46_RS04880	COG0584	glycerophosphoryl diester phosphodiesterase
ATY46_RS04905	COG0473	3-isopropylmalate dehydrogenase activity
ATY46_RS04935	COG2963	transposase activity
ATY46_RS04960	COG0544	peptidyl-prolyl cis-trans isomerase activity
ATY46_RS05000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ATY46_RS05025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ATY46_RS05035	COG0631	protein serine/threonine phosphatase activity
ATY46_RS05100	COG0582	viral genome integration into host DNA
ATY46_RS05110	COG0859	PFAM glycosyl transferase family 9
ATY46_RS05115	COG3642	lipopolysaccharide core region biosynthetic process
ATY46_RS05120	COG1234	tRNA 3'-trailer cleavage
ATY46_RS05125	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ATY46_RS05135	COG0315	cyclic pyranopterin monophosphate synthase activity
ATY46_RS05140	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ATY46_RS05145	COG0314	molybdopterin synthase activity
ATY46_RS05175	COG0537	adenosine 5'-monophosphoramidase activity
ATY46_RS05195	COG0714	Associated with various cellular activities
ATY46_RS05215	COG0242	peptide deformylase activity
ATY46_RS05260	COG3039	Transposase
ATY46_RS05280	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ATY46_RS05285	COG0726	polysaccharide deacetylase
ATY46_RS05335	COG2211	Major facilitator Superfamily
ATY46_RS05345	COG1609	Transcriptional regulator
ATY46_RS05350	COG1028	Short-chain dehydrogenase reductase Sdr
ATY46_RS05355	COG2851	Citrate transporter
ATY46_RS05370	COG0642	Histidine kinase
ATY46_RS05380	COG2197	response regulator
ATY46_RS05405	COG0583	DNA-binding transcription factor activity
ATY46_RS05420	COG4191	Histidine kinase
ATY46_RS05440	COG0280	phosphate acetyltransferase
ATY46_RS05440	COG0281	malic enzyme
ATY46_RS05450	COG2963	transposase activity
ATY46_RS05455	COG2801	Transposase and inactivated derivatives
ATY46_RS05480	COG0352	thiamine-phosphate diphosphorylase activity
ATY46_RS05485	COG1773	rubredoxin
ATY46_RS05490	COG2912	Transglutaminase-like superfamily
ATY46_RS05510	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ATY46_RS05535	COG0006	proline dipeptidase activity
ATY46_RS05550	COG3293	Transposase
ATY46_RS05575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ATY46_RS05590	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ATY46_RS05595	COG1561	YicC-like family, N-terminal region
ATY46_RS05620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ATY46_RS05630	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ATY46_RS05660	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ATY46_RS05710	COG0714	Associated with various cellular activities
ATY46_RS05730	COG2304	oxidoreductase activity
ATY46_RS05750	COG1301	dicarboxylic acid transport
ATY46_RS05755	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ATY46_RS05760	COG4773	Receptor
ATY46_RS05765	COG0739	heme binding
ATY46_RS05770	COG1376	ErfK ybiS ycfS ynhG family protein
ATY46_RS05805	COG1028	Short-chain dehydrogenase reductase Sdr
ATY46_RS05820	COG0642	Histidine kinase
ATY46_RS05840	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ATY46_RS05845	COG4149	molybdate abc transporter
ATY46_RS05850	COG0725	ABC transporter, periplasmic molybdate-binding protein
ATY46_RS05855	COG3453	Protein conserved in bacteria
ATY46_RS05855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ATY46_RS05890	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ATY46_RS05895	COG3293	Transposase
ATY46_RS05910	COG2205	protein histidine kinase activity
ATY46_RS05915	COG0745	RESPONSE REGULATOR receiver
ATY46_RS05965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ATY46_RS05970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ATY46_RS06005	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ATY46_RS06025	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ATY46_RS06040	COG2801	Transposase and inactivated derivatives
ATY46_RS06095	COG2201	protein-glutamate methylesterase activity
ATY46_RS06110	COG2201	protein-glutamate methylesterase activity
ATY46_RS06145	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ATY46_RS06155	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ATY46_RS06160	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ATY46_RS06175	COG1842	Phage shock protein A
ATY46_RS06200	COG0754	glutathionylspermidine amidase activity
ATY46_RS06265	COG0531	amino acid
ATY46_RS06270	COG2197	response regulator
ATY46_RS06285	COG1113	amino acid transport
ATY46_RS06295	COG1271	oxidase subunit
ATY46_RS06300	COG1294	oxidase, subunit
ATY46_RS06310	COG2239	Acts as a magnesium transporter
ATY46_RS06315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ATY46_RS06320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ATY46_RS06330	COG1660	Displays ATPase and GTPase activities
ATY46_RS06335	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ATY46_RS06340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ATY46_RS06355	COG1137	ATPase activity
ATY46_RS06360	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ATY46_RS06370	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ATY46_RS06380	COG0271	Belongs to the BolA IbaG family
ATY46_RS06385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ATY46_RS06405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ATY46_RS06420	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ATY46_RS06430	COG0628	permease
ATY46_RS06440	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ATY46_RS06445	COG3178	'Phosphotransferase
ATY46_RS06465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATY46_RS06470	COG1555	photosystem II stabilization
ATY46_RS06520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ATY46_RS06530	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ATY46_RS06555	COG0228	four-way junction DNA binding
ATY46_RS06560	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ATY46_RS06565	COG0336	Belongs to the RNA methyltransferase TrmD family
ATY46_RS06580	COG0534	Mate efflux family protein
ATY46_RS06605	COG4206	TonB-dependent receptor
ATY46_RS06620	COG2963	transposase activity
ATY46_RS06635	COG0542	response to heat
ATY46_RS06700	COG0019	diaminopimelate decarboxylase activity
ATY46_RS06710	COG2814	Major facilitator Superfamily
ATY46_RS06715	COG4264	IucA IucC family
ATY46_RS06725	COG4772	TonB-dependent receptor
ATY46_RS06735	COG2801	Transposase and inactivated derivatives
ATY46_RS06740	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ATY46_RS06740	COG4651	solute:proton antiporter activity
ATY46_RS06775	COG0488	(ABC) transporter
ATY46_RS06800	COG0657	acetylesterase activity
ATY46_RS06800	COG2755	lipolytic protein G-D-S-L family
ATY46_RS06825	COG2207	Transcriptional regulator
ATY46_RS06830	COG0326	Molecular chaperone. Has ATPase activity
ATY46_RS06850	COG2963	transposase activity
ATY46_RS06890	COG2801	Transposase and inactivated derivatives
ATY46_RS06895	COG2963	transposase activity
ATY46_RS06900	COG3039	Transposase
ATY46_RS06905	COG2146	nitrite reductase [NAD(P)H] activity
ATY46_RS06915	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ATY46_RS06920	COG0719	Fe-S assembly protein
ATY46_RS06925	COG0396	ATPase activity
ATY46_RS06930	COG0719	Fe-S assembly protein
ATY46_RS06935	COG1959	2 iron, 2 sulfur cluster binding
ATY46_RS06955	COG0693	protein deglycase activity
ATY46_RS06995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ATY46_RS07025	COG0519	Catalyzes the synthesis of GMP from XMP
ATY46_RS07040	COG1678	Uncharacterized ACR, COG1678
ATY46_RS07045	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ATY46_RS07060	COG1764	response to oxidative stress
ATY46_RS07070	COG0384	phenazine biosynthesis protein PhzF
ATY46_RS07075	COG0384	phenazine biosynthesis protein PhzF
ATY46_RS07085	COG0527	aspartate kinase activity
ATY46_RS07115	COG0142	geranyltranstransferase activity
ATY46_RS07120	COG0629	single-stranded DNA binding
ATY46_RS07125	COG3706	GGDEF domain
ATY46_RS07125	COG4251	negative regulation of phosphorylation
ATY46_RS07125	COG5001	Diguanylate cyclase
ATY46_RS07125	COG2203	Gaf domain
ATY46_RS07130	COG1028	Short-chain dehydrogenase reductase Sdr
ATY46_RS07130	COG3321	synthase
ATY46_RS07130	COG0604	alcohol dehydrogenase
ATY46_RS07160	COG2879	small protein
ATY46_RS07165	COG1966	Carbon starvation protein
ATY46_RS07170	COG1741	Belongs to the pirin family
ATY46_RS07245	COG1741	Belongs to the pirin family
ATY46_RS07255	COG1515	deoxyribonuclease V activity
ATY46_RS07275	COG3590	peptidase
ATY46_RS07290	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ATY46_RS07295	COG2199	diguanylate cyclase activity
ATY46_RS07295	COG2200	EAL domain
ATY46_RS07295	COG2202	Pas domain
ATY46_RS07300	COG0835	chemotaxis
ATY46_RS07305	COG0840	transmembrane signaling receptor activity
ATY46_RS07310	COG0643	Histidine kinase
ATY46_RS07310	COG2198	Histidine kinase
ATY46_RS07320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ATY46_RS07330	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ATY46_RS07345	COG2205	protein histidine kinase activity
ATY46_RS07370	COG3039	Transposase
ATY46_RS07390	COG3039	Transposase
ATY46_RS07420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ATY46_RS07425	COG0735	belongs to the Fur family
ATY46_RS07470	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ATY46_RS07475	COG0084	hydrolase, TatD family'
ATY46_RS07490	COG1960	acyl-CoA dehydrogenase activity
ATY46_RS07515	COG0367	asparagine synthase
ATY46_RS07525	COG0305	Participates in initiation and elongation during chromosome replication
ATY46_RS07530	COG0415	Belongs to the DNA photolyase family
ATY46_RS07655	COG5002	protein histidine kinase activity
ATY46_RS07655	COG5001	Diguanylate cyclase
ATY46_RS07660	COG1187	pseudouridine synthase activity
ATY46_RS07680	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ATY46_RS07690	COG0475	glutathione-regulated potassium exporter activity
ATY46_RS07695	COG5002	protein histidine kinase activity
ATY46_RS07695	COG5000	phosphorelay sensor kinase activity
ATY46_RS07700	COG0745	RESPONSE REGULATOR receiver
ATY46_RS07730	COG1132	(ABC) transporter
ATY46_RS07740	COG3293	Transposase
ATY46_RS07750	COG3039	Transposase
ATY46_RS07760	COG3039	Transposase
ATY46_RS07765	COG3209	COG3209 Rhs family protein
ATY46_RS07770	COG3039	Transposase
ATY46_RS07795	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ATY46_RS07805	COG4969	Belongs to the N-Me-Phe pilin family
ATY46_RS07810	COG2194	sulfuric ester hydrolase activity
ATY46_RS07830	COG2184	nucleotidyltransferase activity
ATY46_RS07850	COG0045	succinate-CoA ligase (ADP-forming) activity
ATY46_RS07855	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ATY46_RS07865	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ATY46_RS07865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ATY46_RS07870	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ATY46_RS07875	COG0564	pseudouridine synthase activity
ATY46_RS07900	COG3387	PFAM Glycoside hydrolase 15-related
ATY46_RS07905	COG1877	trehalose-phosphatase activity
ATY46_RS07945	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ATY46_RS07965	COG1595	DNA-templated transcription, initiation
ATY46_RS07975	COG1946	Acyl-CoA thioesterase
ATY46_RS07990	COG0824	Thioesterase
ATY46_RS07995	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ATY46_RS08005	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ATY46_RS08010	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ATY46_RS08015	COG0268	Binds directly to 16S ribosomal RNA
ATY46_RS08020	COG0728	peptidoglycan biosynthetic process
ATY46_RS08025	COG0196	riboflavin kinase activity
ATY46_RS08035	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ATY46_RS08040	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ATY46_RS08055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ATY46_RS08060	COG1845	cytochrome c oxidase, subunit III
ATY46_RS08065	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ATY46_RS08085	COG3209	COG3209 Rhs family protein
ATY46_RS08085	COG3209	COG3209 Rhs family protein
ATY46_RS08100	COG2963	transposase activity
ATY46_RS08130	COG2801	Transposase and inactivated derivatives
ATY46_RS08135	COG2963	transposase activity
ATY46_RS08155	COG2963	transposase activity
ATY46_RS08220	COG0632	four-way junction helicase activity
ATY46_RS08230	COG2255	four-way junction helicase activity
ATY46_RS08235	COG0824	Thioesterase
ATY46_RS08245	COG0848	biopolymer transport protein
ATY46_RS08260	COG2885	chlorophyll binding
ATY46_RS08270	COG0602	queuosine metabolic process
ATY46_RS08275	COG1187	pseudouridine synthase activity
ATY46_RS08320	COG3293	Transposase
ATY46_RS08335	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ATY46_RS08495	COG3179	chitinase
ATY46_RS08540	COG4695	Portal protein
ATY46_RS08575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ATY46_RS08590	COG0514	ATP-dependent DNA helicase (RecQ)
ATY46_RS08595	COG0783	Belongs to the Dps family
ATY46_RS08600	COG1643	Atp-dependent helicase
ATY46_RS08620	COG0837	glucose binding
ATY46_RS08630	COG3293	Transposase
ATY46_RS08665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ATY46_RS08675	COG1215	transferase activity, transferring glycosyl groups
ATY46_RS08680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ATY46_RS08690	COG1199	ATP-dependent helicase activity
ATY46_RS08700	COG1397	ADP-ribosylglycohydrolase
ATY46_RS08710	COG0189	ligase activity
ATY46_RS08725	COG0835	chemotaxis
ATY46_RS08730	COG0840	transmembrane signaling receptor activity
ATY46_RS08735	COG0784	Response regulator, receiver
ATY46_RS08735	COG0643	Histidine kinase
ATY46_RS08735	COG2198	Histidine kinase
ATY46_RS08765	COG2304	oxidoreductase activity
ATY46_RS08780	COG1446	asparaginase
ATY46_RS08785	COG3142	Participates in the control of copper homeostasis
ATY46_RS08840	COG3537	Alpha-1,2-mannosidase
ATY46_RS08870	COG3039	Transposase
ATY46_RS08905	COG1472	Belongs to the glycosyl hydrolase 3 family
ATY46_RS08915	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ATY46_RS08925	COG3858	chitin binding
ATY46_RS08925	COG1388	LysM domain
ATY46_RS08940	COG0837	glucose binding
ATY46_RS08945	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ATY46_RS08955	COG0494	nUDIX hydrolase
ATY46_RS08965	COG3956	TIGRFAM MazG family protein
ATY46_RS08980	COG0330	HflC and HflK could
ATY46_RS08995	COG0509	glycine decarboxylation via glycine cleavage system
ATY46_RS09020	COG1960	acyl-CoA dehydrogenase activity
ATY46_RS09030	COG1309	transcriptional regulator
ATY46_RS09035	COG4771	TonB-dependent receptor
ATY46_RS09045	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ATY46_RS09060	COG0516	GMP reductase activity
ATY46_RS09060	COG0517	IMP dehydrogenase activity
ATY46_RS09070	COG1272	protein, Hemolysin III
ATY46_RS09080	COG0739	heme binding
ATY46_RS09085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ATY46_RS09090	COG0626	cystathionine gamma-synthase activity
ATY46_RS09100	COG1760	l-serine dehydratase
ATY46_RS09110	COG2353	YceI-like domain
ATY46_RS09120	COG2353	YceI-like domain
ATY46_RS09190	COG1960	acyl-CoA dehydrogenase activity
ATY46_RS09195	COG1024	Enoyl-CoA hydratase
ATY46_RS09215	COG1250	3-hydroxyacyl-CoA dehydrogenase
ATY46_RS09215	COG1024	Enoyl-CoA hydratase
ATY46_RS09230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ATY46_RS09260	COG1381	Involved in DNA repair and RecF pathway recombination
ATY46_RS09275	COG2954	triphosphatase activity
ATY46_RS09290	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ATY46_RS09295	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
ATY46_RS09300	COG3039	Transposase
ATY46_RS09310	COG3046	protein related to deoxyribodipyrimidine photolyase
ATY46_RS09320	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ATY46_RS09325	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ATY46_RS09330	COG1278	Cold shock
ATY46_RS09355	COG1201	RNA secondary structure unwinding
ATY46_RS09360	COG1793	dna ligase
ATY46_RS09370	COG1793	dna ligase
ATY46_RS09370	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ATY46_RS09400	COG0183	Belongs to the thiolase family
ATY46_RS09420	COG1451	nucleotide metabolic process
ATY46_RS09435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ATY46_RS09475	COG1047	Peptidyl-prolyl cis-trans
ATY46_RS09490	COG2824	Alkylphosphonate utilization operon protein PhnA
ATY46_RS09500	COG1902	pentaerythritol trinitrate reductase activity
ATY46_RS09505	COG2814	Major facilitator Superfamily
ATY46_RS09555	COG3293	Transposase
ATY46_RS09560	COG0392	lysyltransferase activity
ATY46_RS09560	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ATY46_RS09570	COG0251	oxidation-reduction process
ATY46_RS09575	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ATY46_RS09590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ATY46_RS09615	COG1595	DNA-templated transcription, initiation
ATY46_RS09635	COG2878	Part of a membrane complex involved in electron transport
ATY46_RS09645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATY46_RS09645	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATY46_RS09655	COG0346	lactoylglutathione lyase activity
ATY46_RS09665	COG0833	amino acid
ATY46_RS09670	COG2040	homocysteine
ATY46_RS09685	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ATY46_RS09715	COG0529	Catalyzes the synthesis of activated sulfate
ATY46_RS09715	COG2895	sulfate adenylyltransferase (ATP) activity
ATY46_RS09755	COG1981	membrane
ATY46_RS09780	COG1131	(ABC) transporter
ATY46_RS09785	COG4771	TonB-dependent receptor
ATY46_RS09795	COG0825	malonyl-CoA metabolic process
ATY46_RS09815	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ATY46_RS09820	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ATY46_RS09835	COG0750	zinc metalloprotease
ATY46_RS09845	COG0575	Belongs to the CDS family
ATY46_RS09855	COG0233	cytoplasmic translational termination
ATY46_RS09870	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ATY46_RS09930	COG1393	Belongs to the ArsC family
ATY46_RS09945	COG0367	asparagine synthase
ATY46_RS09960	COG4774	siderophore transport
ATY46_RS09995	COG1566	PFAM secretion protein HlyD family protein
ATY46_RS10000	COG2814	Major facilitator Superfamily
ATY46_RS10035	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS10055	COG3039	Transposase
ATY46_RS10060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ATY46_RS10070	COG1960	acyl-CoA dehydrogenase activity
ATY46_RS10100	COG2914	Belongs to the UPF0125 (RnfH) family
ATY46_RS10105	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ATY46_RS10115	COG0497	DNA recombination
ATY46_RS10125	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ATY46_RS10130	COG0443	Heat shock 70 kDa protein
ATY46_RS10135	COG0484	heat shock protein binding
ATY46_RS10140	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ATY46_RS10145	COG1605	Chorismate mutase
ATY46_RS10145	COG0287	Prephenate dehydrogenase
ATY46_RS10160	COG0583	DNA-binding transcription factor activity
ATY46_RS10170	COG1132	(ABC) transporter
ATY46_RS10205	COG2850	peptidyl-arginine hydroxylation
ATY46_RS10250	COG3293	Transposase
ATY46_RS10260	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS10300	COG1131	(ABC) transporter
ATY46_RS10305	COG1725	Transcriptional regulator
ATY46_RS10310	COG0386	Belongs to the glutathione peroxidase family
ATY46_RS10325	COG2900	Belongs to the SlyX family
ATY46_RS10340	COG1609	Transcriptional regulator
ATY46_RS10350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATY46_RS10360	COG1410	methionine synthase
ATY46_RS10360	COG0646	methionine synthase
ATY46_RS10365	COG1410	methionine synthase
ATY46_RS10365	COG0646	methionine synthase
ATY46_RS10370	COG2226	methyltransferase
ATY46_RS10375	COG1960	acyl-CoA dehydrogenase activity
ATY46_RS10400	COG0557	exoribonuclease II activity
ATY46_RS10425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ATY46_RS10435	COG3039	Transposase
ATY46_RS10450	COG3328	transposase activity
ATY46_RS10460	COG1278	Cold shock
ATY46_RS10475	COG3039	Transposase
ATY46_RS10480	COG3039	Transposase
ATY46_RS10525	COG3039	Transposase
ATY46_RS10540	COG2801	Transposase and inactivated derivatives
ATY46_RS10545	COG2963	transposase activity
ATY46_RS10585	COG3039	Transposase
ATY46_RS10595	COG0583	DNA-binding transcription factor activity
ATY46_RS10645	COG2201	protein-glutamate methylesterase activity
ATY46_RS10675	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ATY46_RS10685	COG0531	amino acid
ATY46_RS10690	COG0531	amino acid
ATY46_RS10700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ATY46_RS10705	COG0277	FAD linked oxidase domain protein
ATY46_RS10770	COG0436	Aminotransferase
ATY46_RS10795	COG1187	pseudouridine synthase activity
ATY46_RS10800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ATY46_RS10805	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ATY46_RS10810	COG2350	Protein conserved in bacteria
ATY46_RS10840	COG1175	transmembrane transport
ATY46_RS10845	COG0395	ABC-type sugar transport system, permease component
ATY46_RS10865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ATY46_RS10875	COG2957	Belongs to the agmatine deiminase family
ATY46_RS10890	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ATY46_RS10895	COG0539	negative regulation of cytoplasmic translation
ATY46_RS10900	COG0776	regulation of translation
ATY46_RS10910	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ATY46_RS10915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ATY46_RS10925	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ATY46_RS10930	COG0475	glutathione-regulated potassium exporter activity
ATY46_RS10930	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ATY46_RS10965	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ATY46_RS10980	COG3002	Belongs to the UPF0753 family
ATY46_RS10985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ATY46_RS10990	COG0583	DNA-binding transcription factor activity
ATY46_RS11005	COG1028	Short-chain dehydrogenase reductase Sdr
ATY46_RS11020	COG0583	DNA-binding transcription factor activity
ATY46_RS11035	COG1914	H( )-stimulated, divalent metal cation uptake system
ATY46_RS11055	COG0668	transmembrane transport
ATY46_RS11095	COG1028	Short-chain dehydrogenase reductase Sdr
ATY46_RS11100	COG1183	phosphatidylcholine synthase activity
ATY46_RS11110	COG3243	poly(R)-hydroxyalkanoic acid synthase
ATY46_RS11125	COG0723	plastoquinol--plastocyanin reductase activity
ATY46_RS11125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATY46_RS11135	COG2183	response to ionizing radiation
ATY46_RS11150	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ATY46_RS11165	COG0671	phosphoesterase, PA-phosphatase related
ATY46_RS11190	COG1794	racemase activity, acting on amino acids and derivatives
ATY46_RS11195	COG0697	spore germination
ATY46_RS11200	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ATY46_RS11220	COG1012	belongs to the aldehyde dehydrogenase family
ATY46_RS11255	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ATY46_RS11265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ATY46_RS11270	COG0124	histidyl-tRNA synthetase
ATY46_RS11290	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ATY46_RS11305	COG0131	Imidazoleglycerol-phosphate dehydratase
ATY46_RS11305	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ATY46_RS11315	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ATY46_RS11325	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ATY46_RS11325	COG0140	phosphoribosyl-ATP diphosphatase activity
ATY46_RS11535	COG3293	Transposase
ATY46_RS11545	COG3039	Transposase
ATY46_RS11560	COG3293	Transposase
ATY46_RS11590	COG3293	Transposase
ATY46_RS11610	COG2201	protein-glutamate methylesterase activity
ATY46_RS11635	COG3039	Transposase
ATY46_RS11650	COG3328	transposase activity
ATY46_RS11685	COG0322	excinuclease ABC activity
ATY46_RS11695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ATY46_RS11705	COG1663	tetraacyldisaccharide 4'-kinase activity
ATY46_RS11720	COG0811	peptide transport
ATY46_RS11745	COG4591	ABC-type transport system involved in lipoprotein release permease component
ATY46_RS11760	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ATY46_RS11775	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ATY46_RS11785	COG0354	folic acid binding
ATY46_RS11800	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ATY46_RS11810	COG0363	glucosamine-6-phosphate deaminase activity
ATY46_RS11815	COG0129	dihydroxy-acid dehydratase activity
ATY46_RS11820	COG0800	Aldolase
ATY46_RS11855	COG5002	protein histidine kinase activity
ATY46_RS11855	COG2205	protein histidine kinase activity
ATY46_RS11855	COG0784	Response regulator, receiver
ATY46_RS11865	COG3293	Transposase
ATY46_RS11945	COG0386	Belongs to the glutathione peroxidase family
ATY46_RS12030	COG5001	Diguanylate cyclase
ATY46_RS12030	COG4251	negative regulation of phosphorylation
ATY46_RS12030	COG3706	GGDEF domain
ATY46_RS12030	COG2203	Gaf domain
ATY46_RS12045	COG1472	Belongs to the glycosyl hydrolase 3 family
ATY46_RS12075	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ATY46_RS12090	COG0617	tRNA 3'-terminal CCA addition
ATY46_RS12100	COG1469	GTP cyclohydrolase I activity
ATY46_RS12105	COG0860	N-Acetylmuramoyl-L-alanine amidase
ATY46_RS12120	COG2963	transposase activity
ATY46_RS12160	COG4566	intracellular signal transduction
ATY46_RS12170	COG2963	transposase activity
ATY46_RS12180	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ATY46_RS12185	COG1605	Chorismate mutase
ATY46_RS12185	COG0077	Prephenate dehydratase
ATY46_RS12195	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ATY46_RS12235	COG1228	amidohydrolase
ATY46_RS12240	COG2986	histidine ammonia-lyase
ATY46_RS12250	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ATY46_RS12270	COG2963	transposase activity
ATY46_RS12280	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ATY46_RS12295	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ATY46_RS12310	COG3115	cell septum assembly
ATY46_RS12320	COG0359	binds to the 23S rRNA
ATY46_RS12330	COG0360	Binds together with S18 to 16S ribosomal RNA
ATY46_RS12335	COG0316	Belongs to the HesB IscA family
ATY46_RS12370	COG0288	reversible hydration of carbon dioxide
ATY46_RS12395	COG2925	Exonuclease
ATY46_RS12405	COG0667	Aldo Keto reductase
ATY46_RS12430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ATY46_RS12430	COG0116	Belongs to the methyltransferase superfamily
ATY46_RS12435	COG0488	(ABC) transporter
ATY46_RS12440	COG4133	protoheme IX ABC transporter activity
ATY46_RS12445	COG0488	(ABC) transporter
ATY46_RS12480	COG0494	nUDIX hydrolase
ATY46_RS12490	COG1024	Enoyl-CoA hydratase
ATY46_RS12500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ATY46_RS12515	COG3039	Transposase
ATY46_RS12530	COG3293	Transposase
ATY46_RS12550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ATY46_RS12555	COG0573	inorganic phosphate transmembrane transporter activity
ATY46_RS12570	COG0704	Plays a role in the regulation of phosphate uptake
ATY46_RS12580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ATY46_RS12595	COG3328	transposase activity
ATY46_RS12625	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ATY46_RS12630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ATY46_RS12635	COG1862	Preprotein translocase
ATY46_RS12640	COG0343	queuine tRNA-ribosyltransferase activity
ATY46_RS12720	COG3293	Transposase
ATY46_RS12735	COG0405	Gamma-glutamyltransferase
ATY46_RS12740	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ATY46_RS12755	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ATY46_RS12760	COG0742	ribosomal rna small subunit methyltransferase
ATY46_RS12785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ATY46_RS12820	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS12825	COG3039	Transposase
ATY46_RS12865	COG0303	'Molybdopterin
ATY46_RS12875	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ATY46_RS12885	COG1426	Protein conserved in bacteria
ATY46_RS12895	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ATY46_RS12910	COG1024	Enoyl-CoA hydratase
ATY46_RS12910	COG1250	3-hydroxyacyl-CoA dehydrogenase
ATY46_RS12915	COG0183	Belongs to the thiolase family
ATY46_RS12920	COG0038	chloride channel
ATY46_RS12940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ATY46_RS12960	COG1674	ftsk spoiiie
ATY46_RS12965	COG0492	ferredoxin-NADP+ reductase activity
ATY46_RS12995	COG0542	response to heat
ATY46_RS13010	COG0482	sulfurtransferase activity
ATY46_RS13035	COG5001	Diguanylate cyclase
ATY46_RS13040	COG4585	Histidine kinase
ATY46_RS13050	COG5002	protein histidine kinase activity
ATY46_RS13070	COG0784	Response regulator, receiver
ATY46_RS13070	COG0835	chemotaxis
ATY46_RS13080	COG1558	bacterial-type flagellum-dependent cell motility
ATY46_RS13085	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ATY46_RS13095	COG4787	bacterial-type flagellum-dependent cell motility
ATY46_RS13130	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ATY46_RS13135	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ATY46_RS13165	COG2201	protein-glutamate methylesterase activity
ATY46_RS13185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ATY46_RS13195	COG1028	Short-chain dehydrogenase reductase Sdr
ATY46_RS13225	COG1677	Flagellar hook-basal body complex protein FliE
ATY46_RS13275	COG3190	flagellar
ATY46_RS13290	COG1684	flagellar biosynthetic protein fliR
ATY46_RS13345	COG0643	Histidine kinase
ATY46_RS13345	COG0784	Response regulator, receiver
ATY46_RS13345	COG2198	Histidine kinase
ATY46_RS13360	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS13375	COG3039	Transposase
ATY46_RS13380	COG3209	COG3209 Rhs family protein
ATY46_RS13390	COG3039	Transposase
ATY46_RS13400	COG3039	Transposase
ATY46_RS13495	COG3039	Transposase
ATY46_RS13500	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ATY46_RS13515	COG1271	oxidase subunit
ATY46_RS13520	COG1294	oxidase, subunit
ATY46_RS13545	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ATY46_RS13565	COG0165	Argininosuccinate lyase
ATY46_RS13580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ATY46_RS13585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATY46_RS13595	COG0137	argininosuccinate synthase activity
ATY46_RS13600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ATY46_RS13615	COG2166	iron-sulfur cluster assembly
ATY46_RS13645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ATY46_RS13655	COG4302	ethanolamine ammonia-lyase activity
ATY46_RS13660	COG3293	Transposase
ATY46_RS13685	COG3039	Transposase
ATY46_RS13695	COG4677	pectinesterase activity
ATY46_RS13730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ATY46_RS13735	COG0402	S-adenosylhomocysteine deaminase activity
ATY46_RS13750	COG1509	lysine 2,3-aminomutase activity
ATY46_RS13755	COG5001	Diguanylate cyclase
ATY46_RS13755	COG3300	MHYT domain
ATY46_RS13770	COG0483	inositol monophosphate 1-phosphatase activity
ATY46_RS13775	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ATY46_RS13800	COG0488	(ABC) transporter
ATY46_RS13805	COG0513	Belongs to the DEAD box helicase family
ATY46_RS13825	COG0625	glutathione transferase activity
ATY46_RS13835	COG1671	Belongs to the UPF0178 family
ATY46_RS13840	COG4681	YaeQ
ATY46_RS13845	COG2081	HI0933 family
ATY46_RS13865	COG1028	Short-chain dehydrogenase reductase Sdr
ATY46_RS13885	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ATY46_RS13890	COG0860	N-Acetylmuramoyl-L-alanine amidase
ATY46_RS13895	COG0802	atpase or kinase
ATY46_RS13900	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ATY46_RS13900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ATY46_RS13905	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ATY46_RS13915	COG3293	Transposase
ATY46_RS13935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ATY46_RS13990	COG3328	transposase activity
ATY46_RS14020	COG2969	positive regulation of protein catabolic process
ATY46_RS14025	COG0625	glutathione transferase activity
ATY46_RS14030	COG2857	Cytochrome c1
ATY46_RS14040	COG0723	plastoquinol--plastocyanin reductase activity
ATY46_RS14045	COG0741	lytic transglycosylase activity
ATY46_RS14075	COG1702	phosphate starvation-inducible protein PhoH
ATY46_RS14095	COG4535	Mg2 and Co2 transporter CorC
ATY46_RS14110	COG1012	belongs to the aldehyde dehydrogenase family
ATY46_RS14120	COG1177	transmembrane transport
ATY46_RS14125	COG1176	ABC-type spermidine putrescine transport system, permease component I
ATY46_RS14130	COG3842	ATPase activity
ATY46_RS14165	COG0174	glutamine synthetase
ATY46_RS14170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATY46_RS14180	COG0477	Major facilitator Superfamily
ATY46_RS14190	COG0243	molybdopterin cofactor binding
ATY46_RS14200	COG2223	nitrite transmembrane transporter activity
ATY46_RS14210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ATY46_RS14215	COG1121	(ABC) transporter
ATY46_RS14230	COG2205	protein histidine kinase activity
ATY46_RS14230	COG0784	Response regulator, receiver
ATY46_RS14230	COG5002	protein histidine kinase activity
ATY46_RS14240	COG3039	Transposase
ATY46_RS14255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ATY46_RS14260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ATY46_RS14280	COG1609	Transcriptional regulator
ATY46_RS14285	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ATY46_RS14285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ATY46_RS14290	COG1105	Belongs to the carbohydrate kinase PfkB family
ATY46_RS14295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ATY46_RS14295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ATY46_RS14310	COG3039	Transposase
ATY46_RS14445	COG4771	TonB-dependent receptor
ATY46_RS14455	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ATY46_RS14475	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ATY46_RS14480	COG1360	Flagellar Motor Protein
ATY46_RS14490	COG0835	chemotaxis
ATY46_RS14500	COG0745	RESPONSE REGULATOR receiver
ATY46_RS14530	COG0840	transmembrane signaling receptor activity
ATY46_RS14540	COG0840	transmembrane signaling receptor activity
ATY46_RS14550	COG0840	transmembrane signaling receptor activity
ATY46_RS14555	COG0840	transmembrane signaling receptor activity
ATY46_RS14560	COG0840	transmembrane signaling receptor activity
ATY46_RS14565	COG0840	transmembrane signaling receptor activity
ATY46_RS14580	COG0835	chemotaxis
ATY46_RS14605	COG0840	transmembrane signaling receptor activity
ATY46_RS14635	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ATY46_RS14665	COG0318	PFAM AMP-dependent synthetase and ligase
ATY46_RS14670	COG1024	Enoyl-CoA hydratase
ATY46_RS14675	COG0784	Response regulator, receiver
ATY46_RS14675	COG2205	protein histidine kinase activity
ATY46_RS14675	COG2198	Histidine kinase
ATY46_RS14695	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ATY46_RS14725	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ATY46_RS14735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ATY46_RS14740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ATY46_RS14750	COG0505	Belongs to the CarA family
ATY46_RS14755	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ATY46_RS14765	COG3293	Transposase
ATY46_RS14770	COG2258	MOSC domain
ATY46_RS14775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATY46_RS14825	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ATY46_RS14840	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS14850	COG0477	Major facilitator Superfamily
ATY46_RS14860	COG1070	Carbohydrate kinase
ATY46_RS14875	COG1501	Belongs to the glycosyl hydrolase 31 family
ATY46_RS14890	COG0800	Aldolase
ATY46_RS14895	COG4948	Mandelate Racemase Muconate Lactonizing
ATY46_RS14905	COG3734	2-keto-3-deoxy-galactonokinase
ATY46_RS14910	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ATY46_RS14920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ATY46_RS14935	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ATY46_RS14940	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ATY46_RS14950	COG0351	phosphomethylpyrimidine kinase
ATY46_RS14980	COG0583	DNA-binding transcription factor activity
ATY46_RS14985	COG1741	Belongs to the pirin family
ATY46_RS15005	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ATY46_RS15010	COG0305	Participates in initiation and elongation during chromosome replication
ATY46_RS15030	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ATY46_RS15035	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ATY46_RS15040	COG2137	regulation of response to DNA damage stimulus
ATY46_RS15045	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ATY46_RS15060	COG1546	Belongs to the CinA family
ATY46_RS15065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ATY46_RS15080	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ATY46_RS15090	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ATY46_RS15095	COG1534	Rna-binding protein
ATY46_RS15110	COG1238	metal cluster binding
ATY46_RS15115	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ATY46_RS15120	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ATY46_RS15125	COG2840	Smr protein MutS2
ATY46_RS15135	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ATY46_RS15150	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ATY46_RS15155	COG0148	phosphopyruvate hydratase activity
ATY46_RS15165	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ATY46_RS15170	COG0504	CTP synthase activity
ATY46_RS15200	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ATY46_RS15205	COG0306	phosphate transporter
ATY46_RS15215	COG1253	flavin adenine dinucleotide binding
ATY46_RS15230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATY46_RS15240	COG0477	Major facilitator Superfamily
ATY46_RS15250	COG1132	(ABC) transporter
ATY46_RS15255	COG1136	(ABC) transporter
ATY46_RS15275	COG0438	transferase activity, transferring glycosyl groups
ATY46_RS15285	COG2264	protein methyltransferase activity
ATY46_RS15315	COG2244	polysaccharide biosynthetic process
ATY46_RS15365	COG1595	DNA-templated transcription, initiation
ATY46_RS15380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ATY46_RS15400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ATY46_RS15445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ATY46_RS15450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ATY46_RS15480	COG2963	transposase activity
ATY46_RS15495	COG4644	lycopene metabolic process
ATY46_RS15505	COG1858	cytochrome C peroxidase
ATY46_RS15545	COG0515	serine threonine protein kinase
ATY46_RS15550	COG0631	protein serine/threonine phosphatase activity
ATY46_RS15595	COG3039	Transposase
ATY46_RS15605	COG3039	Transposase
ATY46_RS15655	COG3039	Transposase
ATY46_RS15675	COG3039	Transposase
ATY46_RS15705	COG2801	Transposase and inactivated derivatives
ATY46_RS15715	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ATY46_RS15715	COG0316	Belongs to the HesB IscA family
ATY46_RS15720	COG2154	pterin-4-alpha-carbinolamine dehydratase
ATY46_RS15745	COG1530	ribonuclease E activity
ATY46_RS15755	COG3293	Transposase
ATY46_RS15765	COG1054	Belongs to the UPF0176 family
ATY46_RS15770	COG3039	Transposase
ATY46_RS15790	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ATY46_RS15830	COG3039	Transposase
ATY46_RS15870	COG1648	precorrin-2 dehydrogenase activity
ATY46_RS15870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ATY46_RS15895	COG0746	molybdenum cofactor guanylyltransferase activity
ATY46_RS15960	COG4206	TonB-dependent receptor
ATY46_RS15985	COG4206	TonB-dependent receptor
ATY46_RS16035	COG0531	amino acid
ATY46_RS16050	COG0006	proline dipeptidase activity
ATY46_RS16060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ATY46_RS16075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATY46_RS16080	COG3938	Belongs to the proline racemase family
ATY46_RS16090	COG0552	protein localization to endoplasmic reticulum
ATY46_RS16115	COG0784	Response regulator, receiver
ATY46_RS16115	COG4191	Histidine kinase
ATY46_RS16140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ATY46_RS16245	COG0438	transferase activity, transferring glycosyl groups
ATY46_RS16255	COG0438	transferase activity, transferring glycosyl groups
ATY46_RS16260	COG0438	transferase activity, transferring glycosyl groups
ATY46_RS16330	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ATY46_RS16345	COG2963	transposase activity
ATY46_RS16365	COG0556	nucleotide-excision repair
ATY46_RS16370	COG4969	Belongs to the N-Me-Phe pilin family
ATY46_RS16410	COG1611	Belongs to the LOG family
ATY46_RS16425	COG2095	MarC family integral membrane protein
ATY46_RS16435	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ATY46_RS16470	COG1185	polyribonucleotide nucleotidyltransferase activity
ATY46_RS16475	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ATY46_RS16495	COG0195	Participates in both transcription termination and antitermination
ATY46_RS16500	COG0779	Required for maturation of 30S ribosomal subunits
ATY46_RS16510	COG1007	ATP synthesis coupled electron transport
ATY46_RS16540	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ATY46_RS16545	COG1034	ATP synthesis coupled electron transport
ATY46_RS16550	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ATY46_RS16555	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ATY46_RS16560	COG0649	NAD binding
ATY46_RS16565	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ATY46_RS16575	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ATY46_RS16590	COG0149	triose-phosphate isomerase activity
ATY46_RS16615	COG3293	Transposase
ATY46_RS16645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATY46_RS16650	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ATY46_RS16675	COG0135	phosphoribosylanthranilate isomerase activity
ATY46_RS16680	COG0101	tRNA pseudouridine synthase activity
ATY46_RS16700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ATY46_RS16705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ATY46_RS16710	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ATY46_RS16715	COG2890	protein-(glutamine-N5) methyltransferase activity
ATY46_RS16740	COG0433	COG0433 Predicted ATPase
ATY46_RS16745	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS16760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ATY46_RS16770	COG0412	Dienelactone hydrolase
ATY46_RS16785	COG0717	Belongs to the dCTP deaminase family
ATY46_RS16790	COG0489	protein tyrosine kinase activity
ATY46_RS16825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATY46_RS16830	COG2311	Membrane
ATY46_RS16835	COG1047	Peptidyl-prolyl cis-trans
ATY46_RS16840	COG0791	NLP P60 protein
ATY46_RS16845	COG0791	NLP P60 protein
ATY46_RS16860	COG1301	dicarboxylic acid transport
ATY46_RS16865	COG1785	Belongs to the alkaline phosphatase family
ATY46_RS16870	COG0037	tRNA processing
ATY46_RS16875	COG1722	exodeoxyribonuclease VII activity
ATY46_RS16880	COG0142	geranyltranstransferase activity
ATY46_RS16900	COG0312	modulator of DNA gyrase
ATY46_RS16910	COG0312	modulator of DNA gyrase
ATY46_RS16915	COG3164	Protein of unknown function
ATY46_RS16930	COG2968	Membrane
ATY46_RS16955	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ATY46_RS16975	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ATY46_RS17000	COG3118	belongs to the thioredoxin family
ATY46_RS17015	COG3293	Transposase
ATY46_RS17065	COG3293	Transposase
ATY46_RS17080	COG3039	Transposase
ATY46_RS17100	COG3293	Transposase
ATY46_RS17105	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS17135	COG2801	Transposase and inactivated derivatives
ATY46_RS17145	COG2963	transposase activity
ATY46_RS17180	COG2022	thiamine diphosphate biosynthetic process
ATY46_RS17190	COG0471	metal ion transport
ATY46_RS17190	COG3273	potassium ion transport
ATY46_RS17220	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS17230	COG1970	mechanosensitive ion channel activity
ATY46_RS17245	COG3293	Transposase
ATY46_RS17255	COG2272	Belongs to the type-B carboxylesterase lipase family
ATY46_RS17260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ATY46_RS17290	COG0308	aminopeptidase N
ATY46_RS17295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ATY46_RS17305	COG0529	Catalyzes the synthesis of activated sulfate
ATY46_RS17305	COG2895	sulfate adenylyltransferase (ATP) activity
ATY46_RS17310	COG0175	sulfate reduction
ATY46_RS17315	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ATY46_RS17320	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ATY46_RS17325	COG0175	sulfate reduction
ATY46_RS17345	COG2198	Histidine kinase
ATY46_RS17345	COG0784	Response regulator, receiver
ATY46_RS17345	COG2205	protein histidine kinase activity
ATY46_RS17400	COG3588	fructose-bisphosphate aldolase
ATY46_RS17405	COG0469	pyruvate kinase activity
ATY46_RS17445	COG0753	catalase activity
ATY46_RS17465	COG3039	Transposase
ATY46_RS17485	COG1917	Cupin 2, conserved barrel domain protein
ATY46_RS17485	COG2207	Transcriptional regulator
ATY46_RS17520	COG1506	peptidase
ATY46_RS17520	COG0823	Involved in the tonB-independent uptake of proteins
ATY46_RS17545	COG1297	OPT oligopeptide transporter protein
ATY46_RS17560	COG0587	DNA-directed DNA polymerase activity
ATY46_RS17645	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ATY46_RS17665	COG0732	type I restriction modification DNA specificity domain
ATY46_RS17670	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
ATY46_RS17675	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
ATY46_RS17680	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ATY46_RS17700	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ATY46_RS17860	COG3179	chitinase
ATY46_RS17950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ATY46_RS17955	COG3039	Transposase
ATY46_RS17965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ATY46_RS18025	COG2963	transposase activity
ATY46_RS18055	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ATY46_RS18070	COG2197	response regulator
ATY46_RS18075	COG4585	Histidine kinase
ATY46_RS18090	COG2894	cell division
ATY46_RS18095	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ATY46_RS18105	COG0642	Histidine kinase
ATY46_RS18110	COG0745	RESPONSE REGULATOR receiver
ATY46_RS18115	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ATY46_RS18125	COG2194	sulfuric ester hydrolase activity
ATY46_RS18155	COG3551	Protein conserved in bacteria
ATY46_RS18200	COG2963	transposase activity
ATY46_RS18210	COG3293	Transposase
ATY46_RS18225	COG0203	ribosomal protein L17
ATY46_RS18235	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ATY46_RS18240	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ATY46_RS18250	COG0201	protein transport
ATY46_RS18260	COG1841	ribosomal large subunit assembly
ATY46_RS18290	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ATY46_RS18300	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ATY46_RS18305	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ATY46_RS18310	COG0255	Belongs to the universal ribosomal protein uL29 family
ATY46_RS18315	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ATY46_RS18340	COG0089	rRNA binding
ATY46_RS18345	COG0088	Forms part of the polypeptide exit tunnel
ATY46_RS18350	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ATY46_RS18355	COG0051	transcription antitermination factor activity, RNA binding
ATY46_RS18380	COG0049	tRNA binding
ATY46_RS18385	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ATY46_RS18390	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ATY46_RS18395	COG0085	RNA polymerase activity
ATY46_RS18400	COG0222	ribosome binding
ATY46_RS18405	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ATY46_RS18415	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ATY46_RS18420	COG0250	Participates in transcription elongation, termination and antitermination
ATY46_RS18425	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ATY46_RS18455	COG0012	GTP binding
ATY46_RS18460	COG0193	aminoacyl-tRNA hydrolase activity
ATY46_RS18470	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ATY46_RS18485	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ATY46_RS18500	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ATY46_RS18510	COG0521	Mo-molybdopterin cofactor biosynthetic process
ATY46_RS18530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ATY46_RS18535	COG1295	ribonuclease BN
ATY46_RS18565	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ATY46_RS18575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ATY46_RS18605	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ATY46_RS18630	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ATY46_RS18645	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ATY46_RS18645	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ATY46_RS18690	COG2890	protein-(glutamine-N5) methyltransferase activity
ATY46_RS18700	COG3634	alkyl hydroperoxide reductase activity
ATY46_RS18705	COG0583	DNA-binding transcription factor activity
ATY46_RS18710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ATY46_RS18715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ATY46_RS18775	COG4783	chaperone-mediated protein folding
ATY46_RS18790	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ATY46_RS18800	COG0438	transferase activity, transferring glycosyl groups
ATY46_RS18805	COG0671	phosphoesterase, PA-phosphatase related
ATY46_RS18810	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ATY46_RS18825	COG2833	Protein of unknown function (DUF455)
ATY46_RS18845	COG0285	dihydrofolate synthase activity
ATY46_RS18855	COG0406	alpha-ribazole phosphatase activity
ATY46_RS18885	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ATY46_RS18890	COG4208	sulfate ABC transporter
ATY46_RS18895	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ATY46_RS18900	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ATY46_RS18905	COG0156	8-amino-7-oxononanoate synthase activity
ATY46_RS18930	COG0604	alcohol dehydrogenase
ATY46_RS18935	COG1902	pentaerythritol trinitrate reductase activity
ATY46_RS18935	COG0446	pyridine nucleotide-disulphide oxidoreductase
ATY46_RS18945	COG2963	transposase activity
ATY46_RS19010	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS19020	COG3293	Transposase
ATY46_RS19070	COG3386	PFAM SMP-30 Gluconolaconase
ATY46_RS19090	COG1024	Enoyl-CoA hydratase
ATY46_RS19100	COG0318	PFAM AMP-dependent synthetase and ligase
ATY46_RS19105	COG0583	DNA-binding transcription factor activity
ATY46_RS19145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ATY46_RS19150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ATY46_RS19160	COG2096	Adenosyltransferase
ATY46_RS19165	COG0123	including yeast histone deacetylase and acetoin utilization protein
ATY46_RS19180	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ATY46_RS19190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ATY46_RS19195	COG2967	ApaG domain
ATY46_RS19220	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ATY46_RS19240	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ATY46_RS19255	COG0642	Histidine kinase
ATY46_RS19270	COG4181	ATPase activity
ATY46_RS19280	COG2175	clavaminate synthase activity
ATY46_RS19290	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ATY46_RS19330	COG0667	Aldo Keto reductase
ATY46_RS19340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ATY46_RS19345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATY46_RS19360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ATY46_RS19365	COG4106	trans-aconitate 2-methyltransferase activity
ATY46_RS19375	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ATY46_RS19385	COG3293	Transposase
ATY46_RS19425	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ATY46_RS19430	COG2226	methyltransferase
ATY46_RS19485	COG0604	alcohol dehydrogenase
ATY46_RS19485	COG1028	Short-chain dehydrogenase reductase Sdr
ATY46_RS19485	COG3321	synthase
ATY46_RS19495	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ATY46_RS19510	COG0494	nUDIX hydrolase
ATY46_RS19525	COG4942	peptidase
ATY46_RS19525	COG1388	LysM domain
ATY46_RS19535	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ATY46_RS19550	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ATY46_RS19555	COG1181	Belongs to the D-alanine--D-alanine ligase family
ATY46_RS19560	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ATY46_RS19575	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ATY46_RS19580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ATY46_RS19595	COG3116	cell division
ATY46_RS19600	COG0275	rRNA processing
ATY46_RS19635	COG0792	nuclease activity
ATY46_RS19640	COG1988	membrane-bound metal-dependent
ATY46_RS19645	COG0277	FAD linked oxidase domain protein
ATY46_RS19650	COG0745	RESPONSE REGULATOR receiver
ATY46_RS19655	COG2205	protein histidine kinase activity
ATY46_RS19665	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ATY46_RS19670	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ATY46_RS19695	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ATY46_RS19700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ATY46_RS19725	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ATY46_RS19725	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ATY46_RS19745	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ATY46_RS19765	COG0488	(ABC) transporter
ATY46_RS19790	COG3791	Glutathione-dependent formaldehyde-activating
ATY46_RS19815	COG2205	protein histidine kinase activity
ATY46_RS19865	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ATY46_RS19890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ATY46_RS19900	COG2963	transposase activity
ATY46_RS19905	COG3039	Transposase
ATY46_RS19910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ATY46_RS19915	COG3293	Transposase
ATY46_RS19925	COG3039	Transposase
ATY46_RS19970	COG3039	Transposase
ATY46_RS19980	COG3293	Transposase
ATY46_RS20020	COG0726	polysaccharide deacetylase
ATY46_RS20020	COG1649	PFAM Uncharacterised BCR, COG1649
ATY46_RS20025	COG1215	transferase activity, transferring glycosyl groups
ATY46_RS20035	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ATY46_RS20040	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ATY46_RS20045	COG1609	Transcriptional regulator
ATY46_RS20055	COG2188	Transcriptional regulator
ATY46_RS20070	COG3250	beta-galactosidase activity
ATY46_RS20105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ATY46_RS20110	COG4191	Histidine kinase
ATY46_RS20115	COG0784	Response regulator, receiver
ATY46_RS20120	COG4251	negative regulation of phosphorylation
ATY46_RS20125	COG2823	Periplasmic or secreted lipoprotein
ATY46_RS20130	COG0673	inositol 2-dehydrogenase activity
ATY46_RS20135	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ATY46_RS20175	COG1051	belongs to the nudix hydrolase family
ATY46_RS20175	COG1056	cytidyltransferase-related domain
ATY46_RS20200	COG2921	Belongs to the UPF0250 family
ATY46_RS20210	COG1686	Belongs to the peptidase S11 family
ATY46_RS20220	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ATY46_RS20225	COG2951	lytic endotransglycosylase activity
ATY46_RS20260	COG0772	Belongs to the SEDS family
ATY46_RS20275	COG1792	Involved in formation and maintenance of cell shape
ATY46_RS20285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATY46_RS20335	COG2199	diguanylate cyclase activity
ATY46_RS20340	COG0308	aminopeptidase N
ATY46_RS20370	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ATY46_RS20400	COG0436	Aminotransferase
ATY46_RS20415	COG1505	serine-type exopeptidase activity
ATY46_RS20440	COG0181	hydroxymethylbilane synthase activity
ATY46_RS20450	COG3275	phosphorelay sensor kinase activity
ATY46_RS20485	COG0659	secondary active sulfate transmembrane transporter activity
ATY46_RS20490	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ATY46_RS20490	COG5297	Belongs to the glycosyl hydrolase family 6
ATY46_RS20500	COG0840	transmembrane signaling receptor activity
ATY46_RS20535	COG3293	Transposase
ATY46_RS20575	COG0598	Magnesium transport protein CorA
ATY46_RS20585	COG1113	amino acid transport
ATY46_RS20590	COG5297	Belongs to the glycosyl hydrolase family 6
ATY46_RS20595	COG4305	rare lipoprotein A
ATY46_RS20600	COG0697	spore germination
ATY46_RS20670	COG4221	oxidoreductase activity
ATY46_RS20685	COG2963	transposase activity
ATY46_RS20705	COG0456	acetyltransferase
ATY46_RS20715	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ATY46_RS20745	COG3227	Zinc metalloprotease (Elastase)
ATY46_RS20760	COG2111	Na H antiporter
ATY46_RS20760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ATY46_RS20765	COG1006	Multisubunit Na H antiporter MnhC subunit
ATY46_RS20770	COG0651	ATP synthesis coupled electron transport
ATY46_RS20780	COG2212	antiporter activity
ATY46_RS20785	COG1320	monovalent cation:proton antiporter activity
ATY46_RS20790	COG3293	Transposase
ATY46_RS20800	COG3039	Transposase
ATY46_RS20805	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ATY46_RS20830	COG3483	tryptophan 2,3-dioxygenase activity
ATY46_RS20840	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ATY46_RS20855	COG0022	dehydrogenase e1 component
ATY46_RS20870	COG3293	Transposase
ATY46_RS20880	COG0183	Belongs to the thiolase family
ATY46_RS20930	COG3039	Transposase
ATY46_RS20960	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ATY46_RS20965	COG3023	N-Acetylmuramoyl-L-alanine amidase
ATY46_RS20975	COG4948	Mandelate Racemase Muconate Lactonizing
ATY46_RS21015	COG3293	Transposase
ATY46_RS21025	COG0531	amino acid
ATY46_RS21040	COG3293	Transposase
ATY46_RS21060	COG4682	membrane
ATY46_RS21065	COG3039	Transposase
ATY46_RS21070	COG2133	pyrroloquinoline quinone binding
ATY46_RS21100	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS21110	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ATY46_RS21115	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ATY46_RS21125	COG1610	YqeY-like protein
ATY46_RS21135	COG1295	ribonuclease BN
ATY46_RS21140	COG0358	DNA primase activity
ATY46_RS21200	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ATY46_RS21210	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ATY46_RS21225	COG2963	transposase activity
ATY46_RS21265	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ATY46_RS21270	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ATY46_RS21275	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ATY46_RS21285	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ATY46_RS21290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ATY46_RS21305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ATY46_RS21330	COG2963	transposase activity
ATY46_RS21335	COG2801	Transposase and inactivated derivatives
ATY46_RS21390	COG3039	Transposase
ATY46_RS21400	COG3328	transposase activity
ATY46_RS21405	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ATY46_RS21405	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ATY46_RS21415	COG1473	amidohydrolase
ATY46_RS21420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ATY46_RS21425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ATY46_RS21435	COG5383	Protein conserved in bacteria
ATY46_RS21465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ATY46_RS21470	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ATY46_RS21485	COG0028	Belongs to the TPP enzyme family
ATY46_RS21490	COG4191	Histidine kinase
ATY46_RS21515	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ATY46_RS21530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ATY46_RS21535	COG3177	Filamentation induced by cAMP protein fic
ATY46_RS21550	COG0596	Alpha beta hydrolase
ATY46_RS21555	COG0727	PFAM Uncharacterised protein family (UPF0153)
ATY46_RS21560	COG0318	PFAM AMP-dependent synthetase and ligase
ATY46_RS21565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ATY46_RS21620	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ATY46_RS21630	COG0129	dihydroxy-acid dehydratase activity
ATY46_RS21655	COG3039	Transposase
ATY46_RS21670	COG0408	coproporphyrinogen oxidase activity
ATY46_RS21685	COG2801	Transposase and inactivated derivatives
ATY46_RS21690	COG2963	transposase activity
ATY46_RS21775	COG2353	YceI-like domain
ATY46_RS21810	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ATY46_RS21825	COG3386	PFAM SMP-30 Gluconolaconase
ATY46_RS21870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ATY46_RS21885	COG4771	TonB-dependent receptor
ATY46_RS21895	COG0459	protein refolding
ATY46_RS21930	COG1252	NADH dehydrogenase
ATY46_RS21940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ATY46_RS21945	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ATY46_RS21950	COG2201	protein-glutamate methylesterase activity
ATY46_RS21955	COG2177	Part of the ABC transporter FtsEX involved in
ATY46_RS21960	COG2884	Cell division ATP-binding protein ftsE
ATY46_RS21970	COG3118	belongs to the thioredoxin family
ATY46_RS21975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ATY46_RS21985	COG2963	transposase activity
ATY46_RS21995	COG0729	surface antigen
ATY46_RS22000	COG2911	Protein conserved in bacteria
ATY46_RS22035	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ATY46_RS22050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ATY46_RS22105	COG1733	regulation of RNA biosynthetic process
ATY46_RS22110	COG0702	epimerase
ATY46_RS22140	COG0583	DNA-binding transcription factor activity
ATY46_RS22145	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ATY46_RS22160	COG2205	protein histidine kinase activity
ATY46_RS22165	COG2205	protein histidine kinase activity
ATY46_RS22170	COG0745	RESPONSE REGULATOR receiver
ATY46_RS22200	COG1902	pentaerythritol trinitrate reductase activity
ATY46_RS22205	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ATY46_RS22215	COG2814	Major facilitator Superfamily
ATY46_RS22220	COG0583	DNA-binding transcription factor activity
ATY46_RS22235	COG0084	hydrolase, TatD family'
ATY46_RS22270	COG3293	Transposase
ATY46_RS22290	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ATY46_RS22310	COG2351	hydroxyisourate hydrolase activity
ATY46_RS22350	COG2826	transposase and inactivated derivatives, IS30 family
ATY46_RS22360	COG4770	biotin carboxylase activity
ATY46_RS22365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ATY46_RS22370	COG1960	acyl-CoA dehydrogenase activity
ATY46_RS22430	COG0523	cobalamin synthesis protein
ATY46_RS22440	COG0697	spore germination
ATY46_RS22450	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ATY46_RS22470	COG0457	Tetratricopeptide repeat
ATY46_RS22485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ATY46_RS22500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ATY46_RS22500	COG0519	Catalyzes the synthesis of GMP from XMP
ATY46_RS22510	COG0805	protein transport
ATY46_RS22520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ATY46_RS22530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ATY46_RS22575	COG3661	Belongs to the glycosyl hydrolase 67 family
ATY46_RS22585	COG4948	Mandelate Racemase Muconate Lactonizing
ATY46_RS22595	COG1472	Belongs to the glycosyl hydrolase 3 family
ATY46_RS22600	COG0246	Mannitol dehydrogenase
ATY46_RS22625	COG3693	PFAM glycoside hydrolase, family 10
ATY46_RS22630	COG3693	PFAM glycoside hydrolase, family 10
ATY46_RS22650	COG2211	Major facilitator Superfamily
ATY46_RS22690	COG3293	Transposase
ATY46_RS22700	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ATY46_RS22755	COG1846	Transcriptional regulator
ATY46_RS22760	COG1764	response to oxidative stress
ATY46_RS22845	COG3549	Plasmid maintenance system killer
ATY46_RS22855	COG1074	ATP-dependent DNA helicase activity
ATY46_RS22860	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ATY46_RS22900	COG2032	superoxide dismutase activity
ATY46_RS22905	COG2032	superoxide dismutase activity
ATY46_RS22910	COG2204	response regulator
ATY46_RS22915	COG3852	Histidine kinase
ATY46_RS22920	COG0004	ammonium transporteR
ATY46_RS22925	COG0347	Belongs to the P(II) protein family
ATY46_RS22930	COG0174	glutamine synthetase
ATY46_RS22935	COG1968	undecaprenyl-diphosphatase activity
ATY46_RS22980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ATY46_RS22990	COG2062	phosphohistidine phosphatase, SixA
ATY46_RS22995	COG0489	protein tyrosine kinase activity
ATY46_RS23015	COG1396	sequence-specific DNA binding
ATY46_RS23020	COG3550	peptidyl-serine autophosphorylation
ATY46_RS23025	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ATY46_RS23030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ATY46_RS23045	COG0517	IMP dehydrogenase activity
ATY46_RS23045	COG1125	glycine betaine transport
ATY46_RS23060	COG1119	ATPase activity
ATY46_RS23070	COG1752	Esterase of the alpha-beta hydrolase superfamily
ATY46_RS23085	COG3039	Transposase
ATY46_RS23095	COG2963	transposase activity
ATY46_RS23110	COG0656	L-ascorbic acid biosynthetic process
ATY46_RS23115	COG2130	NADP-dependent
ATY46_RS23120	COG0667	Aldo Keto reductase
ATY46_RS23130	COG1187	pseudouridine synthase activity
ATY46_RS23145	COG1643	Atp-dependent helicase
ATY46_RS23150	COG4807	Protein conserved in bacteria
ATY46_RS23155	COG4948	Mandelate Racemase Muconate Lactonizing
ATY46_RS23160	COG0179	Fumarylacetoacetate (FAA) hydrolase
ATY46_RS23165	COG1028	Short-chain dehydrogenase reductase Sdr
ATY46_RS23185	COG3507	Belongs to the glycosyl hydrolase 43 family
ATY46_RS23230	COG3162	membrane
ATY46_RS23235	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ATY46_RS23250	COG0708	Exodeoxyribonuclease III
ATY46_RS23265	COG2091	lysine biosynthetic process via aminoadipic acid
ATY46_RS23275	COG3540	Alkaline phosphatase
ATY46_RS23305	COG2159	amidohydrolase
ATY46_RS23315	COG2159	amidohydrolase
ATY46_RS23325	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ATY46_RS23330	COG0583	DNA-binding transcription factor activity
ATY46_RS23335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ATY46_RS23350	COG0210	DNA helicase
ATY46_RS23365	COG0531	amino acid
ATY46_RS23370	COG1322	Protein conserved in bacteria
ATY46_RS23380	COG0386	Belongs to the glutathione peroxidase family
ATY46_RS23440	COG0793	Belongs to the peptidase S41A family
ATY46_RS23445	COG4942	peptidase
ATY46_RS23455	COG2234	aminopeptidase activity
ATY46_RS23505	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ATY46_RS23510	COG0302	gtp cyclohydrolase
ATY46_RS23535	COG0477	Major facilitator Superfamily
ATY46_RS23615	COG1929	Belongs to the glycerate kinase type-1 family
ATY46_RS23620	COG2271	Major facilitator Superfamily
ATY46_RS23635	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ATY46_RS23640	COG0861	Integral membrane protein TerC family
ATY46_RS23650	COG0584	glycerophosphoryl diester phosphodiesterase
ATY46_RS23660	COG0671	phosphoesterase, PA-phosphatase related
ATY46_RS23670	COG0726	polysaccharide deacetylase