locus-tag	class	description
EBA22_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EBA22_RS00030	COG0187	DNA topoisomerase II activity
EBA22_RS00040	COG0501	Belongs to the peptidase M48B family
EBA22_RS00080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA22_RS00090	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EBA22_RS00100	COG4772	TonB-dependent receptor
EBA22_RS00115	COG3039	Transposase
EBA22_RS00120	COG1304	FMN binding
EBA22_RS00125	COG1755	Isoprenylcysteine carboxyl methyltransferase
EBA22_RS00150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA22_RS00160	COG3039	Transposase
EBA22_RS00170	COG1136	(ABC) transporter
EBA22_RS00220	COG3039	Transposase
EBA22_RS00230	COG0513	Belongs to the DEAD box helicase family
EBA22_RS00330	COG1858	cytochrome C peroxidase
EBA22_RS00345	COG0702	epimerase
EBA22_RS00370	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EBA22_RS00390	COG1649	PFAM Uncharacterised BCR, COG1649
EBA22_RS00395	COG2354	Protein conserved in bacteria
EBA22_RS00405	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBA22_RS00420	COG3264	Mechanosensitive ion channel
EBA22_RS00420	COG1511	domain protein
EBA22_RS00460	COG3039	Transposase
EBA22_RS00510	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EBA22_RS00590	COG3039	Transposase
EBA22_RS00600	COG3039	Transposase
EBA22_RS00650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA22_RS00660	COG0642	Histidine kinase
EBA22_RS00670	COG1090	epimerase
EBA22_RS00680	COG3039	Transposase
EBA22_RS00705	COG2826	transposase and inactivated derivatives, IS30 family
EBA22_RS00770	COG1136	(ABC) transporter
EBA22_RS00815	COG1272	protein, Hemolysin III
EBA22_RS00820	COG1111	helicase
EBA22_RS00820	COG1205	dead DEAH box helicase
EBA22_RS00880	COG0067	glutamate synthase
EBA22_RS00880	COG0069	glutamate synthase activity
EBA22_RS00880	COG0070	glutamate synthase
EBA22_RS00885	COG0493	'glutamate synthase
EBA22_RS00935	COG1609	Transcriptional regulator
EBA22_RS00970	COG0366	Alpha amylase catalytic
EBA22_RS00975	COG0366	Alpha amylase catalytic
EBA22_RS01030	COG0606	chelatase, subunit chli
EBA22_RS01075	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EBA22_RS01080	COG1166	arginine decarboxylase activity
EBA22_RS01145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EBA22_RS01170	COG1028	Short-chain dehydrogenase reductase Sdr
EBA22_RS01195	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EBA22_RS01210	COG0210	DNA helicase
EBA22_RS01225	COG3132	Protein of unknown function, DUF480
EBA22_RS01230	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EBA22_RS01235	COG0284	orotidine-5'-phosphate decarboxylase activity
EBA22_RS01270	COG2937	Belongs to the GPAT DAPAT family
EBA22_RS01300	COG2755	lipolytic protein G-D-S-L family
EBA22_RS01315	COG3186	Phenylalanine-4-hydroxylase
EBA22_RS01320	COG1522	sequence-specific DNA binding
EBA22_RS01370	COG1064	alcohol dehydrogenase
EBA22_RS01380	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA22_RS01390	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA22_RS01400	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA22_RS01425	COG3039	Transposase
EBA22_RS01435	COG0676	glucose-6-phosphate 1-epimerase activity
EBA22_RS01500	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EBA22_RS01525	COG2853	Lipoprotein
EBA22_RS01540	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA22_RS01545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA22_RS01550	COG1127	ABC transporter
EBA22_RS01625	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA22_RS01640	COG3265	gluconokinase activity
EBA22_RS01645	COG2211	Major facilitator Superfamily
EBA22_RS01650	COG3459	Glycosyltransferase 36 associated
EBA22_RS01660	COG2205	protein histidine kinase activity
EBA22_RS01670	COG1414	Transcriptional regulator
EBA22_RS01675	COG0738	Major facilitator superfamily
EBA22_RS01680	COG3254	rhamnose metabolic process
EBA22_RS01710	COG0339	signal peptide processing
EBA22_RS01740	COG0564	pseudouridine synthase activity
EBA22_RS01750	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBA22_RS01850	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EBA22_RS01860	COG0842	Transport permease protein
EBA22_RS01865	COG1131	(ABC) transporter
EBA22_RS01870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA22_RS01890	COG1476	TRANSCRIPTIONal
EBA22_RS01900	COG4555	ABC transporter
EBA22_RS01935	COG0625	glutathione transferase activity
EBA22_RS01985	COG0583	DNA-binding transcription factor activity
EBA22_RS02020	COG1199	ATP-dependent helicase activity
EBA22_RS02025	COG3039	Transposase
EBA22_RS02045	COG1566	PFAM secretion protein HlyD family protein
EBA22_RS02075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA22_RS02115	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EBA22_RS02115	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EBA22_RS02120	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EBA22_RS02135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EBA22_RS02175	COG3237	CsbD-like
EBA22_RS02180	COG0180	Tryptophanyl-tRNA synthetase
EBA22_RS02185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA22_RS02235	COG0753	catalase activity
EBA22_RS02240	COG1595	DNA-templated transcription, initiation
EBA22_RS02250	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBA22_RS02260	COG0628	permease
EBA22_RS02275	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EBA22_RS02280	COG1040	competence protein
EBA22_RS02285	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EBA22_RS02290	COG0156	8-amino-7-oxononanoate synthase activity
EBA22_RS02305	COG1028	Short-chain dehydrogenase reductase Sdr
EBA22_RS02320	COG0463	Glycosyl transferase, family 2
EBA22_RS02330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EBA22_RS02335	COG3100	YcgL domain-containing protein
EBA22_RS02355	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA22_RS02375	COG2239	Acts as a magnesium transporter
EBA22_RS02390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EBA22_RS02390	COG0045	succinate-CoA ligase (ADP-forming) activity
EBA22_RS02390	COG1042	CoA-binding domain protein
EBA22_RS02405	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA22_RS02415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA22_RS02455	COG3485	protocatechuate 3,4-dioxygenase
EBA22_RS02460	COG3485	protocatechuate 3,4-dioxygenase
EBA22_RS02470	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EBA22_RS02475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA22_RS02480	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EBA22_RS02505	COG4221	oxidoreductase activity
EBA22_RS02530	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EBA22_RS02555	COG0463	Glycosyl transferase, family 2
EBA22_RS02570	COG1475	DNA binding
EBA22_RS02575	COG1192	Involved in chromosome partitioning
EBA22_RS02590	COG0708	Exodeoxyribonuclease III
EBA22_RS02595	COG2211	Major facilitator Superfamily
EBA22_RS02615	COG0739	heme binding
EBA22_RS02660	COG0745	RESPONSE REGULATOR receiver
EBA22_RS02705	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EBA22_RS02730	COG2814	Major facilitator Superfamily
EBA22_RS02745	COG1289	transmembrane transporter activity
EBA22_RS02755	COG1136	(ABC) transporter
EBA22_RS02755	COG0577	efflux transmembrane transporter activity
EBA22_RS02760	COG0151	Belongs to the GarS family
EBA22_RS02770	COG0419	ATPase involved in DNA repair
EBA22_RS02785	COG2267	carboxylic ester hydrolase activity
EBA22_RS02790	COG2267	carboxylic ester hydrolase activity
EBA22_RS02795	COG2267	carboxylic ester hydrolase activity
EBA22_RS02815	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EBA22_RS02875	COG0439	Biotin carboxylase
EBA22_RS02885	COG0511	ligase activity, forming carbon-carbon bonds
EBA22_RS02890	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EBA22_RS02910	COG1324	tolerance protein
EBA22_RS02945	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EBA22_RS02965	COG0534	Mate efflux family protein
EBA22_RS02970	COG0616	signal peptide processing
EBA22_RS02980	COG1028	Short-chain dehydrogenase reductase Sdr
EBA22_RS02995	COG0009	L-threonylcarbamoyladenylate synthase
EBA22_RS03000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA22_RS03000	COG1754	DNA topoisomerase type I activity
EBA22_RS03015	COG2922	Belongs to the Smg family
EBA22_RS03020	COG0758	DNA mediated transformation
EBA22_RS03025	COG1652	LysM domain
EBA22_RS03030	COG0242	peptide deformylase activity
EBA22_RS03035	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EBA22_RS03040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBA22_RS03040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EBA22_RS03090	COG1560	Kdo2-lipid A biosynthetic process
EBA22_RS03100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA22_RS03340	COG1294	oxidase, subunit
EBA22_RS03345	COG1271	oxidase subunit
EBA22_RS03360	COG2204	response regulator
EBA22_RS03390	COG2972	Histidine kinase
EBA22_RS03405	COG0531	amino acid
EBA22_RS03425	COG3590	peptidase
EBA22_RS03440	COG0667	Aldo Keto reductase
EBA22_RS03455	COG3384	dioxygenase
EBA22_RS03465	COG1573	uracil-dna glycosylase
EBA22_RS03475	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EBA22_RS03485	COG0025	NhaP-type Na H and K H
EBA22_RS03490	COG1131	(ABC) transporter
EBA22_RS03495	COG0842	Transport permease protein
EBA22_RS03510	COG1404	Belongs to the peptidase S8 family
EBA22_RS03525	COG0745	RESPONSE REGULATOR receiver
EBA22_RS03575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA22_RS03600	COG2202	Pas domain
EBA22_RS03600	COG2205	protein histidine kinase activity
EBA22_RS03630	COG2813	Specifically methylates the guanine in position
EBA22_RS03635	COG1187	pseudouridine synthase activity
EBA22_RS03640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EBA22_RS03675	COG0697	spore germination
EBA22_RS03685	COG2011	ABC-type metal ion transport system permease component
EBA22_RS03715	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBA22_RS03725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EBA22_RS03745	COG0356	it plays a direct role in the translocation of protons across the membrane
EBA22_RS03755	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EBA22_RS03765	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EBA22_RS03770	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EBA22_RS03775	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EBA22_RS03780	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EBA22_RS03830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA22_RS03835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA22_RS03890	COG0339	signal peptide processing
EBA22_RS03930	COG1956	GAF domain-containing protein
EBA22_RS03935	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EBA22_RS03945	COG0720	synthase
EBA22_RS03955	COG0513	Belongs to the DEAD box helicase family
EBA22_RS04000	COG0626	cystathionine gamma-synthase activity
EBA22_RS04050	COG3328	transposase activity
EBA22_RS04075	COG2086	electron transfer activity
EBA22_RS04100	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EBA22_RS04100	COG0662	Cupin 2, conserved barrel domain protein
EBA22_RS04105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBA22_RS04145	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA22_RS04145	COG3218	ABC-type transport auxiliary lipoprotein component
EBA22_RS04150	COG1127	ABC transporter
EBA22_RS04155	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA22_RS04170	COG0442	prolyl-tRNA aminoacylation
EBA22_RS04180	COG1183	phosphatidylcholine synthase activity
EBA22_RS04200	COG3039	Transposase
EBA22_RS04210	COG3039	Transposase
EBA22_RS04280	COG0525	valine-tRNA ligase activity
EBA22_RS04295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBA22_RS04305	COG0795	lipopolysaccharide-transporting ATPase activity
EBA22_RS04320	COG4974	Belongs to the 'phage' integrase family
EBA22_RS04325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EBA22_RS04330	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBA22_RS04330	COG0047	phosphoribosylformylglycinamidine synthase activity
EBA22_RS04340	COG5295	Hep Hag repeat protein
EBA22_RS04360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA22_RS04370	COG1459	type II secretion system
EBA22_RS04375	COG2165	general secretion pathway protein
EBA22_RS04380	COG4970	Tfp pilus assembly protein FimT
EBA22_RS04385	COG2165	general secretion pathway protein
EBA22_RS04390	COG4795	General secretion pathway protein
EBA22_RS04395	COG3156	type II secretion system protein K
EBA22_RS04400	COG3166	PFAM Fimbrial assembly family protein
EBA22_RS04415	COG1450	Type ii and iii secretion system protein
EBA22_RS04430	COG2188	Transcriptional regulator
EBA22_RS04485	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EBA22_RS04490	COG1518	maintenance of DNA repeat elements
EBA22_RS04535	COG1399	metal-binding, possibly nucleic acid-binding protein
EBA22_RS04560	COG1028	Short-chain dehydrogenase reductase Sdr
EBA22_RS04565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBA22_RS04575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EBA22_RS04580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EBA22_RS04615	COG3829	transcription factor binding
EBA22_RS04650	COG3039	Transposase
EBA22_RS04705	COG2826	transposase and inactivated derivatives, IS30 family
EBA22_RS04715	COG0678	peroxiredoxin activity
EBA22_RS04735	COG0330	HflC and HflK could
EBA22_RS04740	COG0330	HflC and HflK could
EBA22_RS04755	COG0308	aminopeptidase N
EBA22_RS04805	COG1560	Kdo2-lipid A biosynthetic process
EBA22_RS04810	COG1519	Transferase
EBA22_RS04815	COG1538	Outer membrane efflux protein
EBA22_RS04820	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBA22_RS04845	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EBA22_RS04850	COG0066	3-isopropylmalate dehydratase activity
EBA22_RS04885	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EBA22_RS04895	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EBA22_RS04900	COG3710	Transcriptional regulator
EBA22_RS04925	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EBA22_RS04945	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EBA22_RS04975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBA22_RS04985	COG3781	membrane
EBA22_RS05000	COG0625	glutathione transferase activity
EBA22_RS05010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EBA22_RS05015	COG1217	gtp-binding protein TYPA
EBA22_RS05035	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EBA22_RS05175	COG3039	Transposase
EBA22_RS05200	COG0584	glycerophosphoryl diester phosphodiesterase
EBA22_RS05225	COG0473	3-isopropylmalate dehydrogenase activity
EBA22_RS05280	COG0544	peptidyl-prolyl cis-trans isomerase activity
EBA22_RS05320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EBA22_RS05345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA22_RS05355	COG0631	protein serine/threonine phosphatase activity
EBA22_RS05440	COG0582	viral genome integration into host DNA
EBA22_RS05450	COG0859	PFAM glycosyl transferase family 9
EBA22_RS05455	COG3642	lipopolysaccharide core region biosynthetic process
EBA22_RS05460	COG1234	tRNA 3'-trailer cleavage
EBA22_RS05465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EBA22_RS05475	COG0315	cyclic pyranopterin monophosphate synthase activity
EBA22_RS05480	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EBA22_RS05485	COG0314	molybdopterin synthase activity
EBA22_RS05515	COG0537	adenosine 5'-monophosphoramidase activity
EBA22_RS05535	COG0714	Associated with various cellular activities
EBA22_RS05555	COG0242	peptide deformylase activity
EBA22_RS05610	COG3039	Transposase
EBA22_RS05640	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA22_RS05645	COG0726	polysaccharide deacetylase
EBA22_RS05695	COG2211	Major facilitator Superfamily
EBA22_RS05705	COG1609	Transcriptional regulator
EBA22_RS05710	COG1028	Short-chain dehydrogenase reductase Sdr
EBA22_RS05715	COG2851	Citrate transporter
EBA22_RS05735	COG0642	Histidine kinase
EBA22_RS05745	COG2197	response regulator
EBA22_RS05765	COG0583	DNA-binding transcription factor activity
EBA22_RS05780	COG4191	Histidine kinase
EBA22_RS05800	COG0280	phosphate acetyltransferase
EBA22_RS05800	COG0281	malic enzyme
EBA22_RS05835	COG0352	thiamine-phosphate diphosphorylase activity
EBA22_RS05840	COG1773	rubredoxin
EBA22_RS05845	COG2912	Transglutaminase-like superfamily
EBA22_RS05865	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EBA22_RS05890	COG0006	proline dipeptidase activity
EBA22_RS05925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EBA22_RS05940	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EBA22_RS05945	COG1561	YicC-like family, N-terminal region
EBA22_RS05970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA22_RS05980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EBA22_RS06005	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EBA22_RS06055	COG0714	Associated with various cellular activities
EBA22_RS06075	COG2304	oxidoreductase activity
EBA22_RS06095	COG1301	dicarboxylic acid transport
EBA22_RS06100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EBA22_RS06105	COG4773	Receptor
EBA22_RS06110	COG0739	heme binding
EBA22_RS06115	COG1376	ErfK ybiS ycfS ynhG family protein
EBA22_RS06140	COG1022	Amp-dependent synthetase and ligase
EBA22_RS06150	COG1028	Short-chain dehydrogenase reductase Sdr
EBA22_RS06165	COG0642	Histidine kinase
EBA22_RS06185	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EBA22_RS06190	COG4149	molybdate abc transporter
EBA22_RS06195	COG0725	ABC transporter, periplasmic molybdate-binding protein
EBA22_RS06200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA22_RS06200	COG3453	Protein conserved in bacteria
EBA22_RS06230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EBA22_RS06250	COG2205	protein histidine kinase activity
EBA22_RS06255	COG0745	RESPONSE REGULATOR receiver
EBA22_RS06270	COG3039	Transposase
EBA22_RS06305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EBA22_RS06310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EBA22_RS06435	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EBA22_RS06445	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EBA22_RS06450	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EBA22_RS06465	COG1842	Phage shock protein A
EBA22_RS06490	COG0754	glutathionylspermidine amidase activity
EBA22_RS06560	COG0531	amino acid
EBA22_RS06565	COG2197	response regulator
EBA22_RS06580	COG1113	amino acid transport
EBA22_RS06600	COG1271	oxidase subunit
EBA22_RS06605	COG1294	oxidase, subunit
EBA22_RS06615	COG2239	Acts as a magnesium transporter
EBA22_RS06625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA22_RS06630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA22_RS06640	COG1660	Displays ATPase and GTPase activities
EBA22_RS06645	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EBA22_RS06650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA22_RS06665	COG1137	ATPase activity
EBA22_RS06670	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EBA22_RS06680	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EBA22_RS06690	COG0271	Belongs to the BolA IbaG family
EBA22_RS06700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EBA22_RS06720	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EBA22_RS06735	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EBA22_RS06745	COG0628	permease
EBA22_RS06755	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EBA22_RS06760	COG3178	'Phosphotransferase
EBA22_RS06775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA22_RS06780	COG1555	photosystem II stabilization
EBA22_RS06825	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA22_RS06835	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EBA22_RS06860	COG0228	four-way junction DNA binding
EBA22_RS06865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EBA22_RS06870	COG0336	Belongs to the RNA methyltransferase TrmD family
EBA22_RS06885	COG0534	Mate efflux family protein
EBA22_RS06925	COG0542	response to heat
EBA22_RS06965	COG4206	TonB-dependent receptor
EBA22_RS07025	COG0019	diaminopimelate decarboxylase activity
EBA22_RS07040	COG4264	IucA IucC family
EBA22_RS07050	COG4772	TonB-dependent receptor
EBA22_RS07065	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EBA22_RS07065	COG4651	solute:proton antiporter activity
EBA22_RS07100	COG0488	(ABC) transporter
EBA22_RS07125	COG2755	lipolytic protein G-D-S-L family
EBA22_RS07125	COG0657	acetylesterase activity
EBA22_RS07145	COG2207	Transcriptional regulator
EBA22_RS07150	COG0326	Molecular chaperone. Has ATPase activity
EBA22_RS07180	COG3328	transposase activity
EBA22_RS07185	COG0174	glutamine synthetase
EBA22_RS07190	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EBA22_RS07215	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EBA22_RS07250	COG2146	nitrite reductase [NAD(P)H] activity
EBA22_RS07260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EBA22_RS07265	COG0719	Fe-S assembly protein
EBA22_RS07270	COG0396	ATPase activity
EBA22_RS07275	COG0719	Fe-S assembly protein
EBA22_RS07280	COG1959	2 iron, 2 sulfur cluster binding
EBA22_RS07300	COG0693	protein deglycase activity
EBA22_RS07345	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EBA22_RS07380	COG0519	Catalyzes the synthesis of GMP from XMP
EBA22_RS07390	COG1678	Uncharacterized ACR, COG1678
EBA22_RS07395	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EBA22_RS07410	COG1764	response to oxidative stress
EBA22_RS07420	COG0384	phenazine biosynthesis protein PhzF
EBA22_RS07430	COG0527	aspartate kinase activity
EBA22_RS07460	COG0142	geranyltranstransferase activity
EBA22_RS07465	COG0629	single-stranded DNA binding
EBA22_RS07470	COG3706	GGDEF domain
EBA22_RS07470	COG5001	Diguanylate cyclase
EBA22_RS07470	COG2203	Gaf domain
EBA22_RS07470	COG4251	negative regulation of phosphorylation
EBA22_RS07510	COG2879	small protein
EBA22_RS07515	COG1966	Carbon starvation protein
EBA22_RS07520	COG1741	Belongs to the pirin family
EBA22_RS07585	COG1741	Belongs to the pirin family
EBA22_RS07595	COG1515	deoxyribonuclease V activity
EBA22_RS07600	COG0588	phosphoglycerate mutase activity
EBA22_RS07615	COG3590	peptidase
EBA22_RS07630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EBA22_RS07635	COG2202	Pas domain
EBA22_RS07635	COG2200	EAL domain
EBA22_RS07635	COG2199	diguanylate cyclase activity
EBA22_RS07640	COG0835	chemotaxis
EBA22_RS07645	COG0840	transmembrane signaling receptor activity
EBA22_RS07650	COG2198	Histidine kinase
EBA22_RS07650	COG0643	Histidine kinase
EBA22_RS07665	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EBA22_RS07675	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EBA22_RS07695	COG2205	protein histidine kinase activity
EBA22_RS07720	COG3039	Transposase
EBA22_RS07745	COG3039	Transposase
EBA22_RS07750	COG3039	Transposase
EBA22_RS07785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EBA22_RS07790	COG0735	belongs to the Fur family
EBA22_RS07850	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EBA22_RS07855	COG0084	hydrolase, TatD family'
EBA22_RS07870	COG1960	acyl-CoA dehydrogenase activity
EBA22_RS07885	COG0367	asparagine synthase
EBA22_RS07895	COG0305	Participates in initiation and elongation during chromosome replication
EBA22_RS07900	COG0415	Belongs to the DNA photolyase family
EBA22_RS07920	COG1028	Short-chain dehydrogenase reductase Sdr
EBA22_RS07965	COG3039	Transposase
EBA22_RS08025	COG5002	protein histidine kinase activity
EBA22_RS08025	COG5001	Diguanylate cyclase
EBA22_RS08030	COG1187	pseudouridine synthase activity
EBA22_RS08055	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EBA22_RS08065	COG0475	glutathione-regulated potassium exporter activity
EBA22_RS08070	COG5002	protein histidine kinase activity
EBA22_RS08070	COG5000	phosphorelay sensor kinase activity
EBA22_RS08075	COG0745	RESPONSE REGULATOR receiver
EBA22_RS08105	COG1132	(ABC) transporter
EBA22_RS08140	COG3039	Transposase
EBA22_RS08165	COG3039	Transposase
EBA22_RS08210	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EBA22_RS08220	COG4969	Belongs to the N-Me-Phe pilin family
EBA22_RS08225	COG2194	sulfuric ester hydrolase activity
EBA22_RS08265	COG0045	succinate-CoA ligase (ADP-forming) activity
EBA22_RS08270	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EBA22_RS08285	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EBA22_RS08285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA22_RS08290	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA22_RS08295	COG0564	pseudouridine synthase activity
EBA22_RS08320	COG3387	PFAM Glycoside hydrolase 15-related
EBA22_RS08325	COG1877	trehalose-phosphatase activity
EBA22_RS08365	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EBA22_RS08380	COG1595	DNA-templated transcription, initiation
EBA22_RS08390	COG1946	Acyl-CoA thioesterase
EBA22_RS08405	COG0824	Thioesterase
EBA22_RS08410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EBA22_RS08420	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EBA22_RS08425	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EBA22_RS08430	COG0268	Binds directly to 16S ribosomal RNA
EBA22_RS08435	COG0728	peptidoglycan biosynthetic process
EBA22_RS08440	COG0196	riboflavin kinase activity
EBA22_RS08450	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EBA22_RS08455	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EBA22_RS08470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EBA22_RS08475	COG1845	cytochrome c oxidase, subunit III
EBA22_RS08480	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EBA22_RS08500	COG3209	COG3209 Rhs family protein
EBA22_RS08635	COG0632	four-way junction helicase activity
EBA22_RS08645	COG2255	four-way junction helicase activity
EBA22_RS08650	COG0824	Thioesterase
EBA22_RS08660	COG0848	biopolymer transport protein
EBA22_RS08675	COG2885	chlorophyll binding
EBA22_RS08685	COG0602	queuosine metabolic process
EBA22_RS08695	COG1187	pseudouridine synthase activity
EBA22_RS08755	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EBA22_RS08780	COG0514	ATP-dependent DNA helicase (RecQ)
EBA22_RS08790	COG0783	Belongs to the Dps family
EBA22_RS08795	COG1643	Atp-dependent helicase
EBA22_RS08850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA22_RS08860	COG1215	transferase activity, transferring glycosyl groups
EBA22_RS08865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EBA22_RS08875	COG1199	ATP-dependent helicase activity
EBA22_RS08885	COG1397	ADP-ribosylglycohydrolase
EBA22_RS08895	COG0189	ligase activity
EBA22_RS08910	COG0835	chemotaxis
EBA22_RS08915	COG0840	transmembrane signaling receptor activity
EBA22_RS08920	COG0784	Response regulator, receiver
EBA22_RS08920	COG2198	Histidine kinase
EBA22_RS08920	COG0643	Histidine kinase
EBA22_RS08965	COG1446	asparaginase
EBA22_RS08970	COG3142	Participates in the control of copper homeostasis
EBA22_RS09025	COG3537	Alpha-1,2-mannosidase
EBA22_RS09095	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA22_RS09115	COG1388	LysM domain
EBA22_RS09115	COG3858	chitin binding
EBA22_RS09130	COG0837	glucose binding
EBA22_RS09135	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EBA22_RS09145	COG0494	nUDIX hydrolase
EBA22_RS09155	COG3956	TIGRFAM MazG family protein
EBA22_RS09170	COG0330	HflC and HflK could
EBA22_RS09185	COG0509	glycine decarboxylation via glycine cleavage system
EBA22_RS09220	COG1960	acyl-CoA dehydrogenase activity
EBA22_RS09230	COG1309	transcriptional regulator
EBA22_RS09235	COG4771	TonB-dependent receptor
EBA22_RS09245	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EBA22_RS09255	COG0463	Glycosyl transferase, family 2
EBA22_RS09275	COG1272	protein, Hemolysin III
EBA22_RS09285	COG0739	heme binding
EBA22_RS09290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA22_RS09295	COG0626	cystathionine gamma-synthase activity
EBA22_RS09300	COG0460	homoserine dehydrogenase
EBA22_RS09300	COG0527	aspartate kinase activity
EBA22_RS09305	COG1760	l-serine dehydratase
EBA22_RS09320	COG2353	YceI-like domain
EBA22_RS09330	COG2353	YceI-like domain
EBA22_RS09385	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EBA22_RS09405	COG1960	acyl-CoA dehydrogenase activity
EBA22_RS09410	COG1024	Enoyl-CoA hydratase
EBA22_RS09430	COG1024	Enoyl-CoA hydratase
EBA22_RS09430	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA22_RS09445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA22_RS09475	COG1381	Involved in DNA repair and RecF pathway recombination
EBA22_RS09490	COG2954	triphosphatase activity
EBA22_RS09495	COG2954	triphosphatase activity
EBA22_RS09510	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EBA22_RS09515	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EBA22_RS09520	COG3046	protein related to deoxyribodipyrimidine photolyase
EBA22_RS09530	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EBA22_RS09535	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EBA22_RS09540	COG1278	Cold shock
EBA22_RS09560	COG1201	RNA secondary structure unwinding
EBA22_RS09565	COG1793	dna ligase
EBA22_RS09575	COG1793	dna ligase
EBA22_RS09575	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EBA22_RS09605	COG0183	Belongs to the thiolase family
EBA22_RS09630	COG1451	nucleotide metabolic process
EBA22_RS09645	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EBA22_RS09695	COG1047	Peptidyl-prolyl cis-trans
EBA22_RS09710	COG2824	Alkylphosphonate utilization operon protein PhnA
EBA22_RS09725	COG1902	pentaerythritol trinitrate reductase activity
EBA22_RS09730	COG2814	Major facilitator Superfamily
EBA22_RS09785	COG0392	lysyltransferase activity
EBA22_RS09785	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EBA22_RS09795	COG0251	oxidation-reduction process
EBA22_RS09800	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA22_RS09815	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA22_RS09840	COG1595	DNA-templated transcription, initiation
EBA22_RS09860	COG2878	Part of a membrane complex involved in electron transport
EBA22_RS09870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBA22_RS09870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBA22_RS09875	COG3039	Transposase
EBA22_RS09895	COG0833	amino acid
EBA22_RS09900	COG2040	homocysteine
EBA22_RS09915	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA22_RS09955	COG0529	Catalyzes the synthesis of activated sulfate
EBA22_RS09955	COG2895	sulfate adenylyltransferase (ATP) activity
EBA22_RS10000	COG1981	membrane
EBA22_RS10020	COG1131	(ABC) transporter
EBA22_RS10025	COG4771	TonB-dependent receptor
EBA22_RS10035	COG0825	malonyl-CoA metabolic process
EBA22_RS10055	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBA22_RS10060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBA22_RS10080	COG0750	zinc metalloprotease
EBA22_RS10090	COG0575	Belongs to the CDS family
EBA22_RS10100	COG0233	cytoplasmic translational termination
EBA22_RS10115	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EBA22_RS10175	COG1393	Belongs to the ArsC family
EBA22_RS10190	COG0367	asparagine synthase
EBA22_RS10200	COG4774	siderophore transport
EBA22_RS10280	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EBA22_RS10290	COG1960	acyl-CoA dehydrogenase activity
EBA22_RS10305	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EBA22_RS10315	COG2914	Belongs to the UPF0125 (RnfH) family
EBA22_RS10325	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA22_RS10335	COG0497	DNA recombination
EBA22_RS10345	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EBA22_RS10355	COG0484	heat shock protein binding
EBA22_RS10365	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EBA22_RS10370	COG1605	Chorismate mutase
EBA22_RS10370	COG0287	Prephenate dehydrogenase
EBA22_RS10390	COG0583	DNA-binding transcription factor activity
EBA22_RS10405	COG1132	(ABC) transporter
EBA22_RS10440	COG2850	peptidyl-arginine hydroxylation
EBA22_RS10520	COG1131	(ABC) transporter
EBA22_RS10525	COG1725	Transcriptional regulator
EBA22_RS10535	COG0386	Belongs to the glutathione peroxidase family
EBA22_RS10550	COG2900	Belongs to the SlyX family
EBA22_RS10565	COG1609	Transcriptional regulator
EBA22_RS10575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA22_RS10585	COG0646	methionine synthase
EBA22_RS10585	COG1410	methionine synthase
EBA22_RS10590	COG1410	methionine synthase
EBA22_RS10590	COG0646	methionine synthase
EBA22_RS10595	COG2226	methyltransferase
EBA22_RS10600	COG1960	acyl-CoA dehydrogenase activity
EBA22_RS10630	COG0557	exoribonuclease II activity
EBA22_RS10650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA22_RS10670	COG3039	Transposase
EBA22_RS10695	COG3328	transposase activity
EBA22_RS10705	COG1278	Cold shock
EBA22_RS10720	COG3039	Transposase
EBA22_RS10725	COG3039	Transposase
EBA22_RS10775	COG3039	Transposase
EBA22_RS10785	COG0583	DNA-binding transcription factor activity
EBA22_RS10880	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EBA22_RS10890	COG0531	amino acid
EBA22_RS10895	COG0531	amino acid
EBA22_RS10905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EBA22_RS10910	COG0277	FAD linked oxidase domain protein
EBA22_RS10975	COG0436	Aminotransferase
EBA22_RS11000	COG1187	pseudouridine synthase activity
EBA22_RS11005	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EBA22_RS11010	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EBA22_RS11015	COG2350	Protein conserved in bacteria
EBA22_RS11045	COG1175	transmembrane transport
EBA22_RS11050	COG0395	ABC-type sugar transport system, permease component
EBA22_RS11075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA22_RS11085	COG2957	Belongs to the agmatine deiminase family
EBA22_RS11100	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EBA22_RS11105	COG0539	negative regulation of cytoplasmic translation
EBA22_RS11110	COG0776	regulation of translation
EBA22_RS11120	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EBA22_RS11125	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA22_RS11135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EBA22_RS11155	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EBA22_RS11170	COG3002	Belongs to the UPF0753 family
EBA22_RS11175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA22_RS11180	COG0583	DNA-binding transcription factor activity
EBA22_RS11210	COG0583	DNA-binding transcription factor activity
EBA22_RS11215	COG0583	DNA-binding transcription factor activity
EBA22_RS11235	COG1914	H( )-stimulated, divalent metal cation uptake system
EBA22_RS11255	COG0668	transmembrane transport
EBA22_RS11310	COG1028	Short-chain dehydrogenase reductase Sdr
EBA22_RS11315	COG1183	phosphatidylcholine synthase activity
EBA22_RS11325	COG3243	poly(R)-hydroxyalkanoic acid synthase
EBA22_RS11340	COG0723	plastoquinol--plastocyanin reductase activity
EBA22_RS11340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA22_RS11350	COG2183	response to ionizing radiation
EBA22_RS11365	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EBA22_RS11380	COG0671	phosphoesterase, PA-phosphatase related
EBA22_RS11405	COG1794	racemase activity, acting on amino acids and derivatives
EBA22_RS11410	COG0697	spore germination
EBA22_RS11415	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EBA22_RS11435	COG1012	belongs to the aldehyde dehydrogenase family
EBA22_RS11470	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EBA22_RS11490	COG0124	histidyl-tRNA synthetase
EBA22_RS11510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EBA22_RS11525	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EBA22_RS11525	COG0131	Imidazoleglycerol-phosphate dehydratase
EBA22_RS11535	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EBA22_RS11545	COG0140	phosphoribosyl-ATP diphosphatase activity
EBA22_RS11545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EBA22_RS11585	COG0653	protein targeting
EBA22_RS11690	COG2801	Transposase and inactivated derivatives
EBA22_RS11745	COG3328	transposase activity
EBA22_RS11780	COG0322	excinuclease ABC activity
EBA22_RS11790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBA22_RS11800	COG1663	tetraacyldisaccharide 4'-kinase activity
EBA22_RS11815	COG0811	peptide transport
EBA22_RS11840	COG4591	ABC-type transport system involved in lipoprotein release permease component
EBA22_RS11855	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EBA22_RS11870	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EBA22_RS11885	COG0354	folic acid binding
EBA22_RS11900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA22_RS11910	COG0363	glucosamine-6-phosphate deaminase activity
EBA22_RS11915	COG0129	dihydroxy-acid dehydratase activity
EBA22_RS11920	COG0800	Aldolase
EBA22_RS12035	COG0386	Belongs to the glutathione peroxidase family
EBA22_RS12125	COG4251	negative regulation of phosphorylation
EBA22_RS12125	COG3706	GGDEF domain
EBA22_RS12125	COG5001	Diguanylate cyclase
EBA22_RS12125	COG2203	Gaf domain
EBA22_RS12145	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA22_RS12195	COG0617	tRNA 3'-terminal CCA addition
EBA22_RS12205	COG1469	GTP cyclohydrolase I activity
EBA22_RS12210	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA22_RS12265	COG4566	intracellular signal transduction
EBA22_RS12300	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EBA22_RS12305	COG0077	Prephenate dehydratase
EBA22_RS12305	COG1605	Chorismate mutase
EBA22_RS12315	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EBA22_RS12360	COG1228	amidohydrolase
EBA22_RS12365	COG2986	histidine ammonia-lyase
EBA22_RS12375	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EBA22_RS12400	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EBA22_RS12415	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EBA22_RS12430	COG3115	cell septum assembly
EBA22_RS12440	COG0359	binds to the 23S rRNA
EBA22_RS12450	COG0360	Binds together with S18 to 16S ribosomal RNA
EBA22_RS12455	COG0316	Belongs to the HesB IscA family
EBA22_RS12490	COG0288	reversible hydration of carbon dioxide
EBA22_RS12515	COG2925	Exonuclease
EBA22_RS12525	COG0667	Aldo Keto reductase
EBA22_RS12550	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBA22_RS12550	COG0116	Belongs to the methyltransferase superfamily
EBA22_RS12595	COG0494	nUDIX hydrolase
EBA22_RS12605	COG1024	Enoyl-CoA hydratase
EBA22_RS12615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EBA22_RS12630	COG3039	Transposase
EBA22_RS12670	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EBA22_RS12675	COG0573	inorganic phosphate transmembrane transporter activity
EBA22_RS12690	COG0704	Plays a role in the regulation of phosphate uptake
EBA22_RS12700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA22_RS12735	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBA22_RS12740	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBA22_RS12745	COG1862	Preprotein translocase
EBA22_RS12750	COG0343	queuine tRNA-ribosyltransferase activity
EBA22_RS12835	COG0405	Gamma-glutamyltransferase
EBA22_RS12840	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EBA22_RS12855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EBA22_RS12860	COG0742	ribosomal rna small subunit methyltransferase
EBA22_RS12880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EBA22_RS12915	COG3039	Transposase
EBA22_RS12945	COG0303	'Molybdopterin
EBA22_RS12955	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA22_RS12965	COG1426	Protein conserved in bacteria
EBA22_RS12975	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EBA22_RS12990	COG1024	Enoyl-CoA hydratase
EBA22_RS12990	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA22_RS12995	COG0183	Belongs to the thiolase family
EBA22_RS13000	COG0038	chloride channel
EBA22_RS13020	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EBA22_RS13045	COG1674	ftsk spoiiie
EBA22_RS13050	COG0492	ferredoxin-NADP+ reductase activity
EBA22_RS13075	COG0542	response to heat
EBA22_RS13090	COG0482	sulfurtransferase activity
EBA22_RS13115	COG5001	Diguanylate cyclase
EBA22_RS13120	COG4585	Histidine kinase
EBA22_RS13130	COG5002	protein histidine kinase activity
EBA22_RS13150	COG0835	chemotaxis
EBA22_RS13150	COG0784	Response regulator, receiver
EBA22_RS13160	COG1558	bacterial-type flagellum-dependent cell motility
EBA22_RS13165	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EBA22_RS13175	COG4787	bacterial-type flagellum-dependent cell motility
EBA22_RS13215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EBA22_RS13220	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EBA22_RS13250	COG2201	protein-glutamate methylesterase activity
EBA22_RS13270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA22_RS13280	COG1028	Short-chain dehydrogenase reductase Sdr
EBA22_RS13315	COG1677	Flagellar hook-basal body complex protein FliE
EBA22_RS13365	COG3190	flagellar
EBA22_RS13385	COG1684	flagellar biosynthetic protein fliR
EBA22_RS13440	COG0643	Histidine kinase
EBA22_RS13440	COG2198	Histidine kinase
EBA22_RS13440	COG0784	Response regulator, receiver
EBA22_RS13485	COG3039	Transposase
EBA22_RS13565	COG3039	Transposase
EBA22_RS13580	COG4988	ABC transporter
EBA22_RS13595	COG3039	Transposase
EBA22_RS13630	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EBA22_RS13650	COG0165	Argininosuccinate lyase
EBA22_RS13665	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EBA22_RS13670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA22_RS13680	COG0137	argininosuccinate synthase activity
EBA22_RS13685	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EBA22_RS13700	COG2166	iron-sulfur cluster assembly
EBA22_RS13725	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EBA22_RS13765	COG3039	Transposase
EBA22_RS13780	COG4677	pectinesterase activity
EBA22_RS13805	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EBA22_RS13810	COG0402	S-adenosylhomocysteine deaminase activity
EBA22_RS13825	COG1509	lysine 2,3-aminomutase activity
EBA22_RS13830	COG5001	Diguanylate cyclase
EBA22_RS13830	COG3300	MHYT domain
EBA22_RS13845	COG0483	inositol monophosphate 1-phosphatase activity
EBA22_RS13850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA22_RS13875	COG0488	(ABC) transporter
EBA22_RS13880	COG0513	Belongs to the DEAD box helicase family
EBA22_RS13890	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EBA22_RS13900	COG0625	glutathione transferase activity
EBA22_RS13910	COG1671	Belongs to the UPF0178 family
EBA22_RS13915	COG4681	YaeQ
EBA22_RS13920	COG2081	HI0933 family
EBA22_RS13940	COG1028	Short-chain dehydrogenase reductase Sdr
EBA22_RS13965	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EBA22_RS13970	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA22_RS13975	COG0802	atpase or kinase
EBA22_RS13980	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EBA22_RS13980	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EBA22_RS13985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA22_RS14010	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA22_RS14095	COG3328	transposase activity
EBA22_RS14140	COG2969	positive regulation of protein catabolic process
EBA22_RS14145	COG0625	glutathione transferase activity
EBA22_RS14150	COG2857	Cytochrome c1
EBA22_RS14155	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EBA22_RS14160	COG0723	plastoquinol--plastocyanin reductase activity
EBA22_RS14170	COG0741	lytic transglycosylase activity
EBA22_RS14195	COG1702	phosphate starvation-inducible protein PhoH
EBA22_RS14215	COG4535	Mg2 and Co2 transporter CorC
EBA22_RS14230	COG1012	belongs to the aldehyde dehydrogenase family
EBA22_RS14240	COG1177	transmembrane transport
EBA22_RS14250	COG3842	ATPase activity
EBA22_RS14290	COG0174	glutamine synthetase
EBA22_RS14295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA22_RS14305	COG0477	Major facilitator Superfamily
EBA22_RS14315	COG0243	molybdopterin cofactor binding
EBA22_RS14325	COG2223	nitrite transmembrane transporter activity
EBA22_RS14335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EBA22_RS14340	COG1121	(ABC) transporter
EBA22_RS14350	COG2733	membrane
EBA22_RS14355	COG2205	protein histidine kinase activity
EBA22_RS14355	COG0784	Response regulator, receiver
EBA22_RS14355	COG5002	protein histidine kinase activity
EBA22_RS14365	COG3039	Transposase
EBA22_RS14375	COG2902	Dehydrogenase
EBA22_RS14385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA22_RS14390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA22_RS14410	COG1609	Transcriptional regulator
EBA22_RS14415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA22_RS14415	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA22_RS14420	COG1105	Belongs to the carbohydrate kinase PfkB family
EBA22_RS14425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA22_RS14425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA22_RS14440	COG3039	Transposase
EBA22_RS14600	COG3039	Transposase
EBA22_RS14630	COG4771	TonB-dependent receptor
EBA22_RS14640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA22_RS14660	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EBA22_RS14665	COG1360	Flagellar Motor Protein
EBA22_RS14675	COG0835	chemotaxis
EBA22_RS14685	COG0745	RESPONSE REGULATOR receiver
EBA22_RS14710	COG0840	transmembrane signaling receptor activity
EBA22_RS14725	COG0840	transmembrane signaling receptor activity
EBA22_RS14735	COG0840	transmembrane signaling receptor activity
EBA22_RS14745	COG0840	transmembrane signaling receptor activity
EBA22_RS14750	COG0840	transmembrane signaling receptor activity
EBA22_RS14755	COG0840	transmembrane signaling receptor activity
EBA22_RS14760	COG0840	transmembrane signaling receptor activity
EBA22_RS14780	COG0835	chemotaxis
EBA22_RS14805	COG0840	transmembrane signaling receptor activity
EBA22_RS14840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA22_RS14870	COG0318	PFAM AMP-dependent synthetase and ligase
EBA22_RS14875	COG1024	Enoyl-CoA hydratase
EBA22_RS14880	COG0784	Response regulator, receiver
EBA22_RS14880	COG2198	Histidine kinase
EBA22_RS14880	COG2205	protein histidine kinase activity
EBA22_RS14950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EBA22_RS14960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA22_RS14965	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EBA22_RS14975	COG0505	Belongs to the CarA family
EBA22_RS14980	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EBA22_RS14990	COG2258	MOSC domain
EBA22_RS14995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBA22_RS15045	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EBA22_RS15065	COG0477	Major facilitator Superfamily
EBA22_RS15075	COG1070	Carbohydrate kinase
EBA22_RS15085	COG1501	Belongs to the glycosyl hydrolase 31 family
EBA22_RS15100	COG0800	Aldolase
EBA22_RS15105	COG4948	Mandelate Racemase Muconate Lactonizing
EBA22_RS15115	COG3734	2-keto-3-deoxy-galactonokinase
EBA22_RS15120	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EBA22_RS15130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA22_RS15145	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EBA22_RS15150	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EBA22_RS15160	COG0351	phosphomethylpyrimidine kinase
EBA22_RS15190	COG0583	DNA-binding transcription factor activity
EBA22_RS15195	COG1741	Belongs to the pirin family
EBA22_RS15215	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EBA22_RS15220	COG0305	Participates in initiation and elongation during chromosome replication
EBA22_RS15245	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EBA22_RS15250	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EBA22_RS15255	COG2137	regulation of response to DNA damage stimulus
EBA22_RS15260	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EBA22_RS15275	COG1546	Belongs to the CinA family
EBA22_RS15280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EBA22_RS15295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EBA22_RS15305	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EBA22_RS15310	COG1534	Rna-binding protein
EBA22_RS15325	COG1238	metal cluster binding
EBA22_RS15330	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBA22_RS15335	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EBA22_RS15340	COG2840	Smr protein MutS2
EBA22_RS15350	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EBA22_RS15365	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EBA22_RS15370	COG0148	phosphopyruvate hydratase activity
EBA22_RS15380	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EBA22_RS15385	COG0504	CTP synthase activity
EBA22_RS15410	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EBA22_RS15415	COG0306	phosphate transporter
EBA22_RS15430	COG1253	flavin adenine dinucleotide binding
EBA22_RS15445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBA22_RS15465	COG0477	Major facilitator Superfamily
EBA22_RS15475	COG1132	(ABC) transporter
EBA22_RS15480	COG1136	(ABC) transporter
EBA22_RS15500	COG0438	transferase activity, transferring glycosyl groups
EBA22_RS15510	COG2264	protein methyltransferase activity
EBA22_RS15540	COG2244	polysaccharide biosynthetic process
EBA22_RS15590	COG1595	DNA-templated transcription, initiation
EBA22_RS15605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA22_RS15625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA22_RS15660	COG2201	protein-glutamate methylesterase activity
EBA22_RS15680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA22_RS15685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA22_RS15740	COG1858	cytochrome C peroxidase
EBA22_RS15780	COG0515	serine threonine protein kinase
EBA22_RS15785	COG0631	protein serine/threonine phosphatase activity
EBA22_RS15900	COG3039	Transposase
EBA22_RS15920	COG3039	Transposase
EBA22_RS15965	COG0316	Belongs to the HesB IscA family
EBA22_RS15965	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EBA22_RS15970	COG2154	pterin-4-alpha-carbinolamine dehydratase
EBA22_RS15980	COG0428	transporter
EBA22_RS15985	COG0428	transporter
EBA22_RS15990	COG3064	Membrane
EBA22_RS16000	COG1530	ribonuclease E activity
EBA22_RS16020	COG1054	Belongs to the UPF0176 family
EBA22_RS16025	COG3039	Transposase
EBA22_RS16045	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EBA22_RS16085	COG3039	Transposase
EBA22_RS16090	COG3039	Transposase
EBA22_RS16120	COG1648	precorrin-2 dehydrogenase activity
EBA22_RS16120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EBA22_RS16145	COG0746	molybdenum cofactor guanylyltransferase activity
EBA22_RS16225	COG4206	TonB-dependent receptor
EBA22_RS16255	COG4206	TonB-dependent receptor
EBA22_RS16305	COG0531	amino acid
EBA22_RS16320	COG0006	proline dipeptidase activity
EBA22_RS16330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA22_RS16345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA22_RS16350	COG3938	Belongs to the proline racemase family
EBA22_RS16360	COG0552	protein localization to endoplasmic reticulum
EBA22_RS16385	COG0784	Response regulator, receiver
EBA22_RS16385	COG4191	Histidine kinase
EBA22_RS16475	COG3040	lipid binding
EBA22_RS16515	COG0438	transferase activity, transferring glycosyl groups
EBA22_RS16525	COG0438	transferase activity, transferring glycosyl groups
EBA22_RS16530	COG0438	transferase activity, transferring glycosyl groups
EBA22_RS16600	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EBA22_RS16640	COG4969	Belongs to the N-Me-Phe pilin family
EBA22_RS16680	COG1611	Belongs to the LOG family
EBA22_RS16695	COG2095	MarC family integral membrane protein
EBA22_RS16705	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA22_RS16740	COG1185	polyribonucleotide nucleotidyltransferase activity
EBA22_RS16745	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EBA22_RS16765	COG0195	Participates in both transcription termination and antitermination
EBA22_RS16770	COG0779	Required for maturation of 30S ribosomal subunits
EBA22_RS16780	COG1007	ATP synthesis coupled electron transport
EBA22_RS16810	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EBA22_RS16815	COG1034	ATP synthesis coupled electron transport
EBA22_RS16820	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EBA22_RS16825	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EBA22_RS16830	COG0649	NAD binding
EBA22_RS16835	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA22_RS16845	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA22_RS16860	COG0149	triose-phosphate isomerase activity
EBA22_RS16915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBA22_RS16920	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EBA22_RS16945	COG0135	phosphoribosylanthranilate isomerase activity
EBA22_RS16950	COG0101	tRNA pseudouridine synthase activity
EBA22_RS16970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EBA22_RS16975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBA22_RS16980	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EBA22_RS16985	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA22_RS17040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA22_RS17050	COG0412	Dienelactone hydrolase
EBA22_RS17075	COG0717	Belongs to the dCTP deaminase family
EBA22_RS17080	COG0489	protein tyrosine kinase activity
EBA22_RS17125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA22_RS17130	COG2311	Membrane
EBA22_RS17135	COG1047	Peptidyl-prolyl cis-trans
EBA22_RS17140	COG0791	NLP P60 protein
EBA22_RS17145	COG0791	NLP P60 protein
EBA22_RS17165	COG1301	dicarboxylic acid transport
EBA22_RS17170	COG1785	Belongs to the alkaline phosphatase family
EBA22_RS17175	COG0037	tRNA processing
EBA22_RS17180	COG1722	exodeoxyribonuclease VII activity
EBA22_RS17185	COG0142	geranyltranstransferase activity
EBA22_RS17210	COG0312	modulator of DNA gyrase
EBA22_RS17215	COG3028	Belongs to the UPF0307 family
EBA22_RS17220	COG0312	modulator of DNA gyrase
EBA22_RS17230	COG3164	Protein of unknown function
EBA22_RS17245	COG2968	Membrane
EBA22_RS17270	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EBA22_RS17295	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EBA22_RS17325	COG3118	belongs to the thioredoxin family
EBA22_RS17410	COG3039	Transposase
EBA22_RS17415	COG3039	Transposase
EBA22_RS17510	COG2022	thiamine diphosphate biosynthetic process
EBA22_RS17525	COG0471	metal ion transport
EBA22_RS17525	COG3273	potassium ion transport
EBA22_RS17555	COG1970	mechanosensitive ion channel activity
EBA22_RS17580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA22_RS17610	COG0308	aminopeptidase N
EBA22_RS17615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA22_RS17630	COG0529	Catalyzes the synthesis of activated sulfate
EBA22_RS17630	COG2895	sulfate adenylyltransferase (ATP) activity
EBA22_RS17635	COG0175	sulfate reduction
EBA22_RS17640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA22_RS17645	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EBA22_RS17650	COG0175	sulfate reduction
EBA22_RS17670	COG0784	Response regulator, receiver
EBA22_RS17670	COG2198	Histidine kinase
EBA22_RS17670	COG2205	protein histidine kinase activity
EBA22_RS17720	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EBA22_RS17725	COG3588	fructose-bisphosphate aldolase
EBA22_RS17730	COG0469	pyruvate kinase activity
EBA22_RS17775	COG0753	catalase activity
EBA22_RS17800	COG3039	Transposase
EBA22_RS17820	COG1917	Cupin 2, conserved barrel domain protein
EBA22_RS17820	COG2207	Transcriptional regulator
EBA22_RS17850	COG1506	peptidase
EBA22_RS17850	COG0823	Involved in the tonB-independent uptake of proteins
EBA22_RS17875	COG3039	Transposase
EBA22_RS17880	COG1297	OPT oligopeptide transporter protein
EBA22_RS17985	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EBA22_RS18000	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
EBA22_RS18005	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
EBA22_RS18010	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EBA22_RS18030	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EBA22_RS18185	COG3179	chitinase
EBA22_RS18225	COG3179	chitinase
EBA22_RS18355	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA22_RS18410	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA22_RS18420	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA22_RS18510	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EBA22_RS18535	COG2197	response regulator
EBA22_RS18540	COG4585	Histidine kinase
EBA22_RS18560	COG2894	cell division
EBA22_RS18565	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EBA22_RS18575	COG0642	Histidine kinase
EBA22_RS18580	COG0745	RESPONSE REGULATOR receiver
EBA22_RS18585	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EBA22_RS18595	COG2194	sulfuric ester hydrolase activity
EBA22_RS18625	COG3551	Protein conserved in bacteria
EBA22_RS18690	COG0203	ribosomal protein L17
EBA22_RS18700	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EBA22_RS18705	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EBA22_RS18715	COG0201	protein transport
EBA22_RS18725	COG1841	ribosomal large subunit assembly
EBA22_RS18755	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EBA22_RS18765	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EBA22_RS18770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EBA22_RS18775	COG0255	Belongs to the universal ribosomal protein uL29 family
EBA22_RS18780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EBA22_RS18790	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EBA22_RS18805	COG0089	rRNA binding
EBA22_RS18810	COG0088	Forms part of the polypeptide exit tunnel
EBA22_RS18815	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EBA22_RS18820	COG0051	transcription antitermination factor activity, RNA binding
EBA22_RS18840	COG0049	tRNA binding
EBA22_RS18845	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EBA22_RS18850	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EBA22_RS18855	COG0085	RNA polymerase activity
EBA22_RS18860	COG0222	ribosome binding
EBA22_RS18865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EBA22_RS18875	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EBA22_RS18885	COG0250	Participates in transcription elongation, termination and antitermination
EBA22_RS18890	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EBA22_RS18920	COG0012	GTP binding
EBA22_RS18925	COG0193	aminoacyl-tRNA hydrolase activity
EBA22_RS18935	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EBA22_RS18950	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EBA22_RS18965	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EBA22_RS18975	COG0521	Mo-molybdopterin cofactor biosynthetic process
EBA22_RS18995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA22_RS19000	COG1295	ribonuclease BN
EBA22_RS19030	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EBA22_RS19040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EBA22_RS19070	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EBA22_RS19095	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBA22_RS19110	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA22_RS19110	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA22_RS19160	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA22_RS19170	COG3634	alkyl hydroperoxide reductase activity
EBA22_RS19175	COG0583	DNA-binding transcription factor activity
EBA22_RS19185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA22_RS19265	COG4783	chaperone-mediated protein folding
EBA22_RS19280	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EBA22_RS19290	COG0438	transferase activity, transferring glycosyl groups
EBA22_RS19295	COG0671	phosphoesterase, PA-phosphatase related
EBA22_RS19300	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBA22_RS19320	COG2833	Protein of unknown function (DUF455)
EBA22_RS19340	COG0285	dihydrofolate synthase activity
EBA22_RS19350	COG0406	alpha-ribazole phosphatase activity
EBA22_RS19385	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EBA22_RS19390	COG4208	sulfate ABC transporter
EBA22_RS19395	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EBA22_RS19400	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EBA22_RS19405	COG0156	8-amino-7-oxononanoate synthase activity
EBA22_RS19435	COG0604	alcohol dehydrogenase
EBA22_RS19440	COG0446	pyridine nucleotide-disulphide oxidoreductase
EBA22_RS19440	COG1902	pentaerythritol trinitrate reductase activity
EBA22_RS19595	COG3386	PFAM SMP-30 Gluconolaconase
EBA22_RS19615	COG1024	Enoyl-CoA hydratase
EBA22_RS19625	COG0318	PFAM AMP-dependent synthetase and ligase
EBA22_RS19630	COG0583	DNA-binding transcription factor activity
EBA22_RS19670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA22_RS19675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA22_RS19685	COG2096	Adenosyltransferase
EBA22_RS19690	COG0123	including yeast histone deacetylase and acetoin utilization protein
EBA22_RS19705	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EBA22_RS19715	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EBA22_RS19720	COG2967	ApaG domain
EBA22_RS19745	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EBA22_RS19765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EBA22_RS19780	COG0642	Histidine kinase
EBA22_RS19795	COG4181	ATPase activity
EBA22_RS19805	COG2175	clavaminate synthase activity
EBA22_RS19815	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EBA22_RS19855	COG0667	Aldo Keto reductase
EBA22_RS19865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EBA22_RS19870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA22_RS19885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA22_RS19900	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EBA22_RS19955	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EBA22_RS19960	COG2226	methyltransferase
EBA22_RS20015	COG3321	synthase
EBA22_RS20015	COG0604	alcohol dehydrogenase
EBA22_RS20015	COG1028	Short-chain dehydrogenase reductase Sdr
EBA22_RS20030	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EBA22_RS20045	COG0494	nUDIX hydrolase
EBA22_RS20060	COG4942	peptidase
EBA22_RS20060	COG1388	LysM domain
EBA22_RS20070	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EBA22_RS20085	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EBA22_RS20090	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA22_RS20095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBA22_RS20110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA22_RS20115	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EBA22_RS20130	COG3116	cell division
EBA22_RS20135	COG0275	rRNA processing
EBA22_RS20170	COG0792	nuclease activity
EBA22_RS20175	COG1988	membrane-bound metal-dependent
EBA22_RS20180	COG0277	FAD linked oxidase domain protein
EBA22_RS20185	COG0745	RESPONSE REGULATOR receiver
EBA22_RS20190	COG2205	protein histidine kinase activity
EBA22_RS20200	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EBA22_RS20205	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EBA22_RS20230	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EBA22_RS20235	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBA22_RS20240	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EBA22_RS20260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA22_RS20260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA22_RS20280	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EBA22_RS20300	COG0488	(ABC) transporter
EBA22_RS20350	COG2205	protein histidine kinase activity
EBA22_RS20390	COG2205	protein histidine kinase activity
EBA22_RS20410	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EBA22_RS20445	COG3039	Transposase
EBA22_RS20450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EBA22_RS20465	COG3039	Transposase
EBA22_RS20520	COG3039	Transposase
EBA22_RS20570	COG0726	polysaccharide deacetylase
EBA22_RS20570	COG1649	PFAM Uncharacterised BCR, COG1649
EBA22_RS20575	COG1215	transferase activity, transferring glycosyl groups
EBA22_RS20585	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EBA22_RS20590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA22_RS20595	COG1609	Transcriptional regulator
EBA22_RS20605	COG2188	Transcriptional regulator
EBA22_RS20620	COG3250	beta-galactosidase activity
EBA22_RS20675	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EBA22_RS20680	COG4191	Histidine kinase
EBA22_RS20685	COG0784	Response regulator, receiver
EBA22_RS20690	COG4251	negative regulation of phosphorylation
EBA22_RS20695	COG2823	Periplasmic or secreted lipoprotein
EBA22_RS20700	COG0673	inositol 2-dehydrogenase activity
EBA22_RS20705	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EBA22_RS20740	COG1056	cytidyltransferase-related domain
EBA22_RS20740	COG1051	belongs to the nudix hydrolase family
EBA22_RS20775	COG2921	Belongs to the UPF0250 family
EBA22_RS20790	COG1686	Belongs to the peptidase S11 family
EBA22_RS20795	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EBA22_RS20800	COG2951	lytic endotransglycosylase activity
EBA22_RS20820	COG1388	LysM domain
EBA22_RS20820	COG3409	Peptidoglycan-binding domain 1 protein
EBA22_RS20820	COG5632	N-Acetylmuramoyl-L-alanine amidase
EBA22_RS20860	COG0772	Belongs to the SEDS family
EBA22_RS20875	COG1792	Involved in formation and maintenance of cell shape
EBA22_RS20880	COG1077	Cell shape determining protein MreB Mrl
EBA22_RS20885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA22_RS20890	COG3039	Transposase
EBA22_RS20940	COG2199	diguanylate cyclase activity
EBA22_RS20945	COG0308	aminopeptidase N
EBA22_RS20975	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EBA22_RS21005	COG0436	Aminotransferase
EBA22_RS21020	COG1505	serine-type exopeptidase activity
EBA22_RS21045	COG0181	hydroxymethylbilane synthase activity
EBA22_RS21055	COG3275	phosphorelay sensor kinase activity
EBA22_RS21100	COG0659	secondary active sulfate transmembrane transporter activity
EBA22_RS21105	COG5297	Belongs to the glycosyl hydrolase family 6
EBA22_RS21105	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA22_RS21180	COG0598	Magnesium transport protein CorA
EBA22_RS21190	COG1113	amino acid transport
EBA22_RS21200	COG5297	Belongs to the glycosyl hydrolase family 6
EBA22_RS21205	COG4305	rare lipoprotein A
EBA22_RS21210	COG0697	spore germination
EBA22_RS21270	COG4221	oxidoreductase activity
EBA22_RS21300	COG0456	acetyltransferase
EBA22_RS21310	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EBA22_RS21345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA22_RS21345	COG2111	Na H antiporter
EBA22_RS21350	COG1006	Multisubunit Na H antiporter MnhC subunit
EBA22_RS21355	COG0651	ATP synthesis coupled electron transport
EBA22_RS21365	COG2212	antiporter activity
EBA22_RS21370	COG1320	monovalent cation:proton antiporter activity
EBA22_RS21385	COG3039	Transposase
EBA22_RS21390	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EBA22_RS21410	COG3104	oligopeptide transport
EBA22_RS21415	COG3483	tryptophan 2,3-dioxygenase activity
EBA22_RS21425	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EBA22_RS21460	COG0183	Belongs to the thiolase family
EBA22_RS21515	COG3039	Transposase
EBA22_RS21550	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EBA22_RS21555	COG3023	N-Acetylmuramoyl-L-alanine amidase
EBA22_RS21565	COG4948	Mandelate Racemase Muconate Lactonizing
EBA22_RS21605	COG0531	amino acid
EBA22_RS21640	COG4682	membrane
EBA22_RS21645	COG3039	Transposase
EBA22_RS21650	COG2133	pyrroloquinoline quinone binding
EBA22_RS21690	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EBA22_RS21695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EBA22_RS21705	COG1610	YqeY-like protein
EBA22_RS21725	COG1295	ribonuclease BN
EBA22_RS21730	COG0358	DNA primase activity
EBA22_RS21795	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EBA22_RS21810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EBA22_RS21860	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EBA22_RS21865	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EBA22_RS21870	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EBA22_RS21880	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EBA22_RS21885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EBA22_RS21900	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EBA22_RS21980	COG3039	Transposase
EBA22_RS21995	COG3328	transposase activity
EBA22_RS22010	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EBA22_RS22010	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EBA22_RS22020	COG1473	amidohydrolase
EBA22_RS22025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA22_RS22030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA22_RS22045	COG5383	Protein conserved in bacteria
EBA22_RS22090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EBA22_RS22095	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EBA22_RS22110	COG0028	Belongs to the TPP enzyme family
EBA22_RS22115	COG4191	Histidine kinase
EBA22_RS22140	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EBA22_RS22155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA22_RS22160	COG3177	Filamentation induced by cAMP protein fic
EBA22_RS22175	COG0596	Alpha beta hydrolase
EBA22_RS22180	COG0727	PFAM Uncharacterised protein family (UPF0153)
EBA22_RS22185	COG0318	PFAM AMP-dependent synthetase and ligase
EBA22_RS22190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EBA22_RS22250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EBA22_RS22260	COG0129	dihydroxy-acid dehydratase activity
EBA22_RS22300	COG0408	coproporphyrinogen oxidase activity
EBA22_RS22355	COG3039	Transposase
EBA22_RS22405	COG2353	YceI-like domain
EBA22_RS22435	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA22_RS22450	COG3386	PFAM SMP-30 Gluconolaconase
EBA22_RS22485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EBA22_RS22500	COG4771	TonB-dependent receptor
EBA22_RS22510	COG0459	protein refolding
EBA22_RS22535	COG1252	NADH dehydrogenase
EBA22_RS22545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA22_RS22550	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EBA22_RS22555	COG3437	response regulator, receiver
EBA22_RS22560	COG2177	Part of the ABC transporter FtsEX involved in
EBA22_RS22565	COG2884	Cell division ATP-binding protein ftsE
EBA22_RS22575	COG3118	belongs to the thioredoxin family
EBA22_RS22580	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EBA22_RS22595	COG0729	surface antigen
EBA22_RS22600	COG2911	Protein conserved in bacteria
EBA22_RS22635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBA22_RS22650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBA22_RS22710	COG1733	regulation of RNA biosynthetic process
EBA22_RS22715	COG0702	epimerase
EBA22_RS22745	COG0583	DNA-binding transcription factor activity
EBA22_RS22750	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA22_RS22770	COG0745	RESPONSE REGULATOR receiver
EBA22_RS22800	COG1902	pentaerythritol trinitrate reductase activity
EBA22_RS22805	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EBA22_RS22815	COG2814	Major facilitator Superfamily
EBA22_RS22820	COG0583	DNA-binding transcription factor activity
EBA22_RS22840	COG0084	hydrolase, TatD family'
EBA22_RS22890	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EBA22_RS22910	COG2072	flavoprotein involved in K transport
EBA22_RS22965	COG4770	biotin carboxylase activity
EBA22_RS22970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EBA22_RS22975	COG1960	acyl-CoA dehydrogenase activity
EBA22_RS23030	COG0523	cobalamin synthesis protein
EBA22_RS23040	COG0697	spore germination
EBA22_RS23050	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EBA22_RS23065	COG4771	TonB-dependent receptor
EBA22_RS23070	COG0457	Tetratricopeptide repeat
EBA22_RS23085	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA22_RS23110	COG0519	Catalyzes the synthesis of GMP from XMP
EBA22_RS23110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA22_RS23120	COG0805	protein transport
EBA22_RS23130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA22_RS23140	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EBA22_RS23190	COG3661	Belongs to the glycosyl hydrolase 67 family
EBA22_RS23200	COG4948	Mandelate Racemase Muconate Lactonizing
EBA22_RS23210	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA22_RS23215	COG0246	Mannitol dehydrogenase
EBA22_RS23240	COG3693	PFAM glycoside hydrolase, family 10
EBA22_RS23265	COG2211	Major facilitator Superfamily
EBA22_RS23310	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EBA22_RS23360	COG1846	Transcriptional regulator
EBA22_RS23365	COG1764	response to oxidative stress
EBA22_RS23465	COG3549	Plasmid maintenance system killer
EBA22_RS23475	COG1074	ATP-dependent DNA helicase activity
EBA22_RS23480	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EBA22_RS23490	COG1196	nuclear chromosome segregation
EBA22_RS23530	COG2032	superoxide dismutase activity
EBA22_RS23535	COG2032	superoxide dismutase activity
EBA22_RS23540	COG2204	response regulator
EBA22_RS23545	COG3852	Histidine kinase
EBA22_RS23550	COG0004	ammonium transporteR
EBA22_RS23555	COG0347	Belongs to the P(II) protein family
EBA22_RS23560	COG0174	glutamine synthetase
EBA22_RS23565	COG1968	undecaprenyl-diphosphatase activity
EBA22_RS23610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA22_RS23620	COG2062	phosphohistidine phosphatase, SixA
EBA22_RS23625	COG0489	protein tyrosine kinase activity
EBA22_RS23645	COG1396	sequence-specific DNA binding
EBA22_RS23650	COG3550	peptidyl-serine autophosphorylation
EBA22_RS23655	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EBA22_RS23660	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA22_RS23675	COG1125	glycine betaine transport
EBA22_RS23675	COG0517	IMP dehydrogenase activity
EBA22_RS23690	COG1119	ATPase activity
EBA22_RS23700	COG1752	Esterase of the alpha-beta hydrolase superfamily
EBA22_RS23715	COG3039	Transposase
EBA22_RS23740	COG0656	L-ascorbic acid biosynthetic process
EBA22_RS23745	COG2130	NADP-dependent
EBA22_RS23750	COG0667	Aldo Keto reductase
EBA22_RS23760	COG1187	pseudouridine synthase activity
EBA22_RS23775	COG1643	Atp-dependent helicase
EBA22_RS23780	COG4807	Protein conserved in bacteria
EBA22_RS23785	COG4948	Mandelate Racemase Muconate Lactonizing
EBA22_RS23795	COG0179	Fumarylacetoacetate (FAA) hydrolase
EBA22_RS23800	COG1028	Short-chain dehydrogenase reductase Sdr
EBA22_RS23820	COG3507	Belongs to the glycosyl hydrolase 43 family
EBA22_RS23860	COG3162	membrane
EBA22_RS23865	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EBA22_RS23880	COG0708	Exodeoxyribonuclease III
EBA22_RS23895	COG2091	lysine biosynthetic process via aminoadipic acid
EBA22_RS23905	COG3540	Alkaline phosphatase
EBA22_RS23935	COG2159	amidohydrolase
EBA22_RS23960	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EBA22_RS23965	COG0583	DNA-binding transcription factor activity
EBA22_RS23970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA22_RS23990	COG0210	DNA helicase
EBA22_RS24005	COG0531	amino acid
EBA22_RS24015	COG1322	Protein conserved in bacteria
EBA22_RS24025	COG0386	Belongs to the glutathione peroxidase family
EBA22_RS24080	COG0793	Belongs to the peptidase S41A family
EBA22_RS24085	COG4942	peptidase
EBA22_RS24095	COG2234	aminopeptidase activity
EBA22_RS24145	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EBA22_RS24150	COG0302	gtp cyclohydrolase
EBA22_RS24175	COG0477	Major facilitator Superfamily
EBA22_RS24280	COG1929	Belongs to the glycerate kinase type-1 family
EBA22_RS24285	COG2271	Major facilitator Superfamily
EBA22_RS24300	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBA22_RS24310	COG0861	Integral membrane protein TerC family
EBA22_RS24320	COG0584	glycerophosphoryl diester phosphodiesterase
EBA22_RS24330	COG0671	phosphoesterase, PA-phosphatase related
EBA22_RS24340	COG0726	polysaccharide deacetylase