locus-tag	class	description
EBA25_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EBA25_RS00030	COG0187	DNA topoisomerase II activity
EBA25_RS00040	COG0501	Belongs to the peptidase M48B family
EBA25_RS00080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA25_RS00090	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EBA25_RS00100	COG4772	TonB-dependent receptor
EBA25_RS00115	COG3039	Transposase
EBA25_RS00120	COG1304	FMN binding
EBA25_RS00125	COG1755	Isoprenylcysteine carboxyl methyltransferase
EBA25_RS00150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA25_RS00160	COG3039	Transposase
EBA25_RS00170	COG1136	(ABC) transporter
EBA25_RS00220	COG3039	Transposase
EBA25_RS00230	COG0513	Belongs to the DEAD box helicase family
EBA25_RS00330	COG1858	cytochrome C peroxidase
EBA25_RS00345	COG0702	epimerase
EBA25_RS00370	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EBA25_RS00390	COG1649	PFAM Uncharacterised BCR, COG1649
EBA25_RS00395	COG2354	Protein conserved in bacteria
EBA25_RS00405	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBA25_RS00420	COG3264	Mechanosensitive ion channel
EBA25_RS00420	COG1511	domain protein
EBA25_RS00460	COG3039	Transposase
EBA25_RS00510	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EBA25_RS00590	COG3039	Transposase
EBA25_RS00600	COG3039	Transposase
EBA25_RS00650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA25_RS00660	COG0642	Histidine kinase
EBA25_RS00670	COG1090	epimerase
EBA25_RS00680	COG3039	Transposase
EBA25_RS00705	COG2826	transposase and inactivated derivatives, IS30 family
EBA25_RS00770	COG1136	(ABC) transporter
EBA25_RS00815	COG1272	protein, Hemolysin III
EBA25_RS00820	COG1205	dead DEAH box helicase
EBA25_RS00820	COG1111	helicase
EBA25_RS00880	COG0070	glutamate synthase
EBA25_RS00880	COG0069	glutamate synthase activity
EBA25_RS00880	COG0067	glutamate synthase
EBA25_RS00885	COG0493	'glutamate synthase
EBA25_RS00940	COG1609	Transcriptional regulator
EBA25_RS00975	COG0366	Alpha amylase catalytic
EBA25_RS00980	COG0366	Alpha amylase catalytic
EBA25_RS01035	COG0606	chelatase, subunit chli
EBA25_RS01080	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EBA25_RS01085	COG1166	arginine decarboxylase activity
EBA25_RS01150	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EBA25_RS01175	COG1028	Short-chain dehydrogenase reductase Sdr
EBA25_RS01200	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EBA25_RS01215	COG0210	DNA helicase
EBA25_RS01230	COG3132	Protein of unknown function, DUF480
EBA25_RS01235	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EBA25_RS01240	COG0284	orotidine-5'-phosphate decarboxylase activity
EBA25_RS01275	COG2937	Belongs to the GPAT DAPAT family
EBA25_RS01305	COG2755	lipolytic protein G-D-S-L family
EBA25_RS01320	COG3186	Phenylalanine-4-hydroxylase
EBA25_RS01325	COG1522	sequence-specific DNA binding
EBA25_RS01375	COG1064	alcohol dehydrogenase
EBA25_RS01385	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA25_RS01395	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA25_RS01405	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA25_RS01430	COG3039	Transposase
EBA25_RS01440	COG0676	glucose-6-phosphate 1-epimerase activity
EBA25_RS01505	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EBA25_RS01530	COG2853	Lipoprotein
EBA25_RS01545	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA25_RS01550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA25_RS01555	COG1127	ABC transporter
EBA25_RS01630	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA25_RS01645	COG3265	gluconokinase activity
EBA25_RS01650	COG2211	Major facilitator Superfamily
EBA25_RS01655	COG3459	Glycosyltransferase 36 associated
EBA25_RS01665	COG2205	protein histidine kinase activity
EBA25_RS01675	COG1414	Transcriptional regulator
EBA25_RS01680	COG0738	Major facilitator superfamily
EBA25_RS01685	COG3254	rhamnose metabolic process
EBA25_RS01715	COG0339	signal peptide processing
EBA25_RS01745	COG0564	pseudouridine synthase activity
EBA25_RS01755	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBA25_RS01855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EBA25_RS01865	COG0842	Transport permease protein
EBA25_RS01870	COG1131	(ABC) transporter
EBA25_RS01875	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA25_RS01895	COG1476	TRANSCRIPTIONal
EBA25_RS01905	COG4555	ABC transporter
EBA25_RS01940	COG0625	glutathione transferase activity
EBA25_RS01990	COG0583	DNA-binding transcription factor activity
EBA25_RS02025	COG1199	ATP-dependent helicase activity
EBA25_RS02030	COG3039	Transposase
EBA25_RS02050	COG1566	PFAM secretion protein HlyD family protein
EBA25_RS02080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA25_RS02120	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EBA25_RS02120	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EBA25_RS02125	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EBA25_RS02140	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EBA25_RS02180	COG3237	CsbD-like
EBA25_RS02185	COG0180	Tryptophanyl-tRNA synthetase
EBA25_RS02190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA25_RS02240	COG0753	catalase activity
EBA25_RS02245	COG1595	DNA-templated transcription, initiation
EBA25_RS02255	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBA25_RS02265	COG0628	permease
EBA25_RS02280	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EBA25_RS02285	COG1040	competence protein
EBA25_RS02290	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EBA25_RS02295	COG0156	8-amino-7-oxononanoate synthase activity
EBA25_RS02310	COG1028	Short-chain dehydrogenase reductase Sdr
EBA25_RS02325	COG0463	Glycosyl transferase, family 2
EBA25_RS02335	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EBA25_RS02340	COG3100	YcgL domain-containing protein
EBA25_RS02360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA25_RS02380	COG2239	Acts as a magnesium transporter
EBA25_RS02395	COG1042	CoA-binding domain protein
EBA25_RS02395	COG0045	succinate-CoA ligase (ADP-forming) activity
EBA25_RS02395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EBA25_RS02410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA25_RS02420	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA25_RS02460	COG3485	protocatechuate 3,4-dioxygenase
EBA25_RS02465	COG3485	protocatechuate 3,4-dioxygenase
EBA25_RS02475	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EBA25_RS02480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA25_RS02485	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EBA25_RS02510	COG4221	oxidoreductase activity
EBA25_RS02535	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EBA25_RS02560	COG0463	Glycosyl transferase, family 2
EBA25_RS02575	COG1475	DNA binding
EBA25_RS02580	COG1192	Involved in chromosome partitioning
EBA25_RS02595	COG0708	Exodeoxyribonuclease III
EBA25_RS02600	COG2211	Major facilitator Superfamily
EBA25_RS02620	COG0739	heme binding
EBA25_RS02665	COG0745	RESPONSE REGULATOR receiver
EBA25_RS02710	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EBA25_RS02735	COG2814	Major facilitator Superfamily
EBA25_RS02750	COG1289	transmembrane transporter activity
EBA25_RS02760	COG0577	efflux transmembrane transporter activity
EBA25_RS02760	COG1136	(ABC) transporter
EBA25_RS02765	COG0151	Belongs to the GarS family
EBA25_RS02775	COG0419	ATPase involved in DNA repair
EBA25_RS02790	COG2267	carboxylic ester hydrolase activity
EBA25_RS02795	COG2267	carboxylic ester hydrolase activity
EBA25_RS02800	COG2267	carboxylic ester hydrolase activity
EBA25_RS02820	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EBA25_RS02880	COG0439	Biotin carboxylase
EBA25_RS02890	COG0511	ligase activity, forming carbon-carbon bonds
EBA25_RS02895	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EBA25_RS02915	COG1324	tolerance protein
EBA25_RS02950	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EBA25_RS02970	COG0534	Mate efflux family protein
EBA25_RS02975	COG0616	signal peptide processing
EBA25_RS02985	COG1028	Short-chain dehydrogenase reductase Sdr
EBA25_RS03000	COG0009	L-threonylcarbamoyladenylate synthase
EBA25_RS03005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA25_RS03005	COG1754	DNA topoisomerase type I activity
EBA25_RS03020	COG2922	Belongs to the Smg family
EBA25_RS03025	COG0758	DNA mediated transformation
EBA25_RS03030	COG1652	LysM domain
EBA25_RS03035	COG0242	peptide deformylase activity
EBA25_RS03040	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EBA25_RS03045	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EBA25_RS03045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBA25_RS03095	COG1560	Kdo2-lipid A biosynthetic process
EBA25_RS03105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA25_RS03350	COG1294	oxidase, subunit
EBA25_RS03355	COG1271	oxidase subunit
EBA25_RS03370	COG2204	response regulator
EBA25_RS03400	COG2972	Histidine kinase
EBA25_RS03415	COG0531	amino acid
EBA25_RS03435	COG3590	peptidase
EBA25_RS03450	COG0667	Aldo Keto reductase
EBA25_RS03465	COG3384	dioxygenase
EBA25_RS03475	COG1573	uracil-dna glycosylase
EBA25_RS03485	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EBA25_RS03495	COG0025	NhaP-type Na H and K H
EBA25_RS03500	COG1131	(ABC) transporter
EBA25_RS03505	COG0842	Transport permease protein
EBA25_RS03520	COG1404	Belongs to the peptidase S8 family
EBA25_RS03535	COG0745	RESPONSE REGULATOR receiver
EBA25_RS03585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA25_RS03610	COG2205	protein histidine kinase activity
EBA25_RS03610	COG2202	Pas domain
EBA25_RS03640	COG2813	Specifically methylates the guanine in position
EBA25_RS03645	COG1187	pseudouridine synthase activity
EBA25_RS03650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EBA25_RS03685	COG0697	spore germination
EBA25_RS03695	COG2011	ABC-type metal ion transport system permease component
EBA25_RS03725	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBA25_RS03735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EBA25_RS03755	COG0356	it plays a direct role in the translocation of protons across the membrane
EBA25_RS03765	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EBA25_RS03775	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EBA25_RS03780	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EBA25_RS03785	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EBA25_RS03790	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EBA25_RS03840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA25_RS03845	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA25_RS03900	COG0339	signal peptide processing
EBA25_RS03940	COG1956	GAF domain-containing protein
EBA25_RS03945	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EBA25_RS03955	COG0720	synthase
EBA25_RS03965	COG0513	Belongs to the DEAD box helicase family
EBA25_RS04010	COG0626	cystathionine gamma-synthase activity
EBA25_RS04060	COG3328	transposase activity
EBA25_RS04085	COG2086	electron transfer activity
EBA25_RS04110	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EBA25_RS04110	COG0662	Cupin 2, conserved barrel domain protein
EBA25_RS04115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBA25_RS04155	COG3218	ABC-type transport auxiliary lipoprotein component
EBA25_RS04155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA25_RS04160	COG1127	ABC transporter
EBA25_RS04165	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA25_RS04180	COG0442	prolyl-tRNA aminoacylation
EBA25_RS04190	COG1183	phosphatidylcholine synthase activity
EBA25_RS04210	COG3039	Transposase
EBA25_RS04220	COG3039	Transposase
EBA25_RS04285	COG0525	valine-tRNA ligase activity
EBA25_RS04300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBA25_RS04310	COG0795	lipopolysaccharide-transporting ATPase activity
EBA25_RS04325	COG4974	Belongs to the 'phage' integrase family
EBA25_RS04330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EBA25_RS04335	COG0047	phosphoribosylformylglycinamidine synthase activity
EBA25_RS04335	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBA25_RS04345	COG5295	Hep Hag repeat protein
EBA25_RS04365	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA25_RS04375	COG1459	type II secretion system
EBA25_RS04380	COG2165	general secretion pathway protein
EBA25_RS04385	COG4970	Tfp pilus assembly protein FimT
EBA25_RS04390	COG2165	general secretion pathway protein
EBA25_RS04395	COG4795	General secretion pathway protein
EBA25_RS04400	COG3156	type II secretion system protein K
EBA25_RS04405	COG3166	PFAM Fimbrial assembly family protein
EBA25_RS04420	COG1450	Type ii and iii secretion system protein
EBA25_RS04435	COG2188	Transcriptional regulator
EBA25_RS04490	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EBA25_RS04495	COG1518	maintenance of DNA repeat elements
EBA25_RS04540	COG1399	metal-binding, possibly nucleic acid-binding protein
EBA25_RS04565	COG1028	Short-chain dehydrogenase reductase Sdr
EBA25_RS04570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBA25_RS04580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EBA25_RS04585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EBA25_RS04620	COG3829	transcription factor binding
EBA25_RS04655	COG3039	Transposase
EBA25_RS04710	COG2826	transposase and inactivated derivatives, IS30 family
EBA25_RS04720	COG0678	peroxiredoxin activity
EBA25_RS04740	COG0330	HflC and HflK could
EBA25_RS04745	COG0330	HflC and HflK could
EBA25_RS04760	COG0308	aminopeptidase N
EBA25_RS04810	COG1560	Kdo2-lipid A biosynthetic process
EBA25_RS04815	COG1519	Transferase
EBA25_RS04820	COG1538	Outer membrane efflux protein
EBA25_RS04825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBA25_RS04850	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EBA25_RS04855	COG0066	3-isopropylmalate dehydratase activity
EBA25_RS04890	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EBA25_RS04900	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EBA25_RS04905	COG3710	Transcriptional regulator
EBA25_RS04930	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EBA25_RS04950	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EBA25_RS04980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBA25_RS04990	COG3781	membrane
EBA25_RS05005	COG0625	glutathione transferase activity
EBA25_RS05015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EBA25_RS05020	COG1217	gtp-binding protein TYPA
EBA25_RS05040	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EBA25_RS05180	COG3039	Transposase
EBA25_RS05205	COG0584	glycerophosphoryl diester phosphodiesterase
EBA25_RS05230	COG0473	3-isopropylmalate dehydrogenase activity
EBA25_RS05285	COG0544	peptidyl-prolyl cis-trans isomerase activity
EBA25_RS05325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EBA25_RS05350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA25_RS05360	COG0631	protein serine/threonine phosphatase activity
EBA25_RS05445	COG0582	viral genome integration into host DNA
EBA25_RS05455	COG0859	PFAM glycosyl transferase family 9
EBA25_RS05460	COG3642	lipopolysaccharide core region biosynthetic process
EBA25_RS05465	COG1234	tRNA 3'-trailer cleavage
EBA25_RS05470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EBA25_RS05480	COG0315	cyclic pyranopterin monophosphate synthase activity
EBA25_RS05485	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EBA25_RS05490	COG0314	molybdopterin synthase activity
EBA25_RS05520	COG0537	adenosine 5'-monophosphoramidase activity
EBA25_RS05540	COG0714	Associated with various cellular activities
EBA25_RS05560	COG0242	peptide deformylase activity
EBA25_RS05615	COG3039	Transposase
EBA25_RS05645	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA25_RS05650	COG0726	polysaccharide deacetylase
EBA25_RS05700	COG2211	Major facilitator Superfamily
EBA25_RS05710	COG1609	Transcriptional regulator
EBA25_RS05715	COG1028	Short-chain dehydrogenase reductase Sdr
EBA25_RS05720	COG2851	Citrate transporter
EBA25_RS05740	COG0642	Histidine kinase
EBA25_RS05750	COG2197	response regulator
EBA25_RS05770	COG0583	DNA-binding transcription factor activity
EBA25_RS05785	COG4191	Histidine kinase
EBA25_RS05805	COG0281	malic enzyme
EBA25_RS05805	COG0280	phosphate acetyltransferase
EBA25_RS05840	COG0352	thiamine-phosphate diphosphorylase activity
EBA25_RS05845	COG1773	rubredoxin
EBA25_RS05850	COG2912	Transglutaminase-like superfamily
EBA25_RS05870	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EBA25_RS05895	COG0006	proline dipeptidase activity
EBA25_RS05930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EBA25_RS05945	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EBA25_RS05950	COG1561	YicC-like family, N-terminal region
EBA25_RS05975	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA25_RS05985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EBA25_RS06010	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EBA25_RS06060	COG0714	Associated with various cellular activities
EBA25_RS06080	COG2304	oxidoreductase activity
EBA25_RS06100	COG1301	dicarboxylic acid transport
EBA25_RS06105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EBA25_RS06110	COG4773	Receptor
EBA25_RS06115	COG0739	heme binding
EBA25_RS06120	COG1376	ErfK ybiS ycfS ynhG family protein
EBA25_RS06145	COG1022	Amp-dependent synthetase and ligase
EBA25_RS06155	COG1028	Short-chain dehydrogenase reductase Sdr
EBA25_RS06170	COG0642	Histidine kinase
EBA25_RS06190	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EBA25_RS06195	COG4149	molybdate abc transporter
EBA25_RS06200	COG0725	ABC transporter, periplasmic molybdate-binding protein
EBA25_RS06205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA25_RS06205	COG3453	Protein conserved in bacteria
EBA25_RS06235	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EBA25_RS06255	COG2205	protein histidine kinase activity
EBA25_RS06260	COG0745	RESPONSE REGULATOR receiver
EBA25_RS06275	COG3039	Transposase
EBA25_RS06310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EBA25_RS06315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EBA25_RS06480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EBA25_RS06490	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EBA25_RS06495	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EBA25_RS06510	COG1842	Phage shock protein A
EBA25_RS06535	COG0754	glutathionylspermidine amidase activity
EBA25_RS06605	COG0531	amino acid
EBA25_RS06610	COG2197	response regulator
EBA25_RS06625	COG1113	amino acid transport
EBA25_RS06645	COG1271	oxidase subunit
EBA25_RS06650	COG1294	oxidase, subunit
EBA25_RS06660	COG2239	Acts as a magnesium transporter
EBA25_RS06670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA25_RS06675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA25_RS06685	COG1660	Displays ATPase and GTPase activities
EBA25_RS06690	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EBA25_RS06695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA25_RS06710	COG1137	ATPase activity
EBA25_RS06715	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EBA25_RS06725	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EBA25_RS06735	COG0271	Belongs to the BolA IbaG family
EBA25_RS06745	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EBA25_RS06765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EBA25_RS06780	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EBA25_RS06790	COG0628	permease
EBA25_RS06800	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EBA25_RS06805	COG3178	'Phosphotransferase
EBA25_RS06820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA25_RS06825	COG1555	photosystem II stabilization
EBA25_RS06870	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA25_RS06880	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EBA25_RS06905	COG0228	four-way junction DNA binding
EBA25_RS06910	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EBA25_RS06915	COG0336	Belongs to the RNA methyltransferase TrmD family
EBA25_RS06930	COG0534	Mate efflux family protein
EBA25_RS06970	COG0542	response to heat
EBA25_RS07010	COG4206	TonB-dependent receptor
EBA25_RS07070	COG0019	diaminopimelate decarboxylase activity
EBA25_RS07080	COG2814	Major facilitator Superfamily
EBA25_RS07085	COG4264	IucA IucC family
EBA25_RS07095	COG4772	TonB-dependent receptor
EBA25_RS07110	COG4651	solute:proton antiporter activity
EBA25_RS07110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EBA25_RS07145	COG0488	(ABC) transporter
EBA25_RS07170	COG2755	lipolytic protein G-D-S-L family
EBA25_RS07170	COG0657	acetylesterase activity
EBA25_RS07195	COG2207	Transcriptional regulator
EBA25_RS07200	COG0326	Molecular chaperone. Has ATPase activity
EBA25_RS07230	COG3328	transposase activity
EBA25_RS07235	COG0174	glutamine synthetase
EBA25_RS07240	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EBA25_RS07250	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EBA25_RS07265	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EBA25_RS07295	COG2146	nitrite reductase [NAD(P)H] activity
EBA25_RS07305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EBA25_RS07310	COG0719	Fe-S assembly protein
EBA25_RS07315	COG0396	ATPase activity
EBA25_RS07320	COG0719	Fe-S assembly protein
EBA25_RS07325	COG1959	2 iron, 2 sulfur cluster binding
EBA25_RS07345	COG0693	protein deglycase activity
EBA25_RS07390	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EBA25_RS07425	COG0519	Catalyzes the synthesis of GMP from XMP
EBA25_RS07435	COG1678	Uncharacterized ACR, COG1678
EBA25_RS07440	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EBA25_RS07455	COG1764	response to oxidative stress
EBA25_RS07465	COG0384	phenazine biosynthesis protein PhzF
EBA25_RS07475	COG0527	aspartate kinase activity
EBA25_RS07505	COG0142	geranyltranstransferase activity
EBA25_RS07510	COG0629	single-stranded DNA binding
EBA25_RS07515	COG4251	negative regulation of phosphorylation
EBA25_RS07515	COG2203	Gaf domain
EBA25_RS07515	COG5001	Diguanylate cyclase
EBA25_RS07515	COG3706	GGDEF domain
EBA25_RS07555	COG2879	small protein
EBA25_RS07560	COG1966	Carbon starvation protein
EBA25_RS07565	COG1741	Belongs to the pirin family
EBA25_RS07630	COG1741	Belongs to the pirin family
EBA25_RS07640	COG1515	deoxyribonuclease V activity
EBA25_RS07645	COG0588	phosphoglycerate mutase activity
EBA25_RS07660	COG3590	peptidase
EBA25_RS07675	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EBA25_RS07680	COG2202	Pas domain
EBA25_RS07680	COG2200	EAL domain
EBA25_RS07680	COG2199	diguanylate cyclase activity
EBA25_RS07685	COG0835	chemotaxis
EBA25_RS07690	COG0840	transmembrane signaling receptor activity
EBA25_RS07695	COG0643	Histidine kinase
EBA25_RS07695	COG2198	Histidine kinase
EBA25_RS07710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EBA25_RS07720	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EBA25_RS07740	COG2205	protein histidine kinase activity
EBA25_RS07765	COG3039	Transposase
EBA25_RS07790	COG3039	Transposase
EBA25_RS07795	COG3039	Transposase
EBA25_RS07830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EBA25_RS07835	COG0735	belongs to the Fur family
EBA25_RS07895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EBA25_RS07900	COG0084	hydrolase, TatD family'
EBA25_RS07915	COG1960	acyl-CoA dehydrogenase activity
EBA25_RS07930	COG0367	asparagine synthase
EBA25_RS07940	COG0305	Participates in initiation and elongation during chromosome replication
EBA25_RS07945	COG0415	Belongs to the DNA photolyase family
EBA25_RS07965	COG1028	Short-chain dehydrogenase reductase Sdr
EBA25_RS08010	COG3039	Transposase
EBA25_RS08070	COG5002	protein histidine kinase activity
EBA25_RS08070	COG5001	Diguanylate cyclase
EBA25_RS08075	COG1187	pseudouridine synthase activity
EBA25_RS08100	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EBA25_RS08110	COG0475	glutathione-regulated potassium exporter activity
EBA25_RS08115	COG5002	protein histidine kinase activity
EBA25_RS08115	COG5000	phosphorelay sensor kinase activity
EBA25_RS08120	COG0745	RESPONSE REGULATOR receiver
EBA25_RS08150	COG1132	(ABC) transporter
EBA25_RS08180	COG3039	Transposase
EBA25_RS08205	COG3039	Transposase
EBA25_RS08250	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EBA25_RS08260	COG4969	Belongs to the N-Me-Phe pilin family
EBA25_RS08265	COG2194	sulfuric ester hydrolase activity
EBA25_RS08305	COG0045	succinate-CoA ligase (ADP-forming) activity
EBA25_RS08310	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EBA25_RS08325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA25_RS08325	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EBA25_RS08330	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA25_RS08335	COG0564	pseudouridine synthase activity
EBA25_RS08360	COG3387	PFAM Glycoside hydrolase 15-related
EBA25_RS08365	COG1877	trehalose-phosphatase activity
EBA25_RS08405	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EBA25_RS08420	COG1595	DNA-templated transcription, initiation
EBA25_RS08430	COG1946	Acyl-CoA thioesterase
EBA25_RS08445	COG0824	Thioesterase
EBA25_RS08450	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EBA25_RS08460	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EBA25_RS08465	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EBA25_RS08470	COG0268	Binds directly to 16S ribosomal RNA
EBA25_RS08475	COG0728	peptidoglycan biosynthetic process
EBA25_RS08480	COG0196	riboflavin kinase activity
EBA25_RS08490	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EBA25_RS08495	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EBA25_RS08510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EBA25_RS08515	COG1845	cytochrome c oxidase, subunit III
EBA25_RS08520	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EBA25_RS08540	COG3209	COG3209 Rhs family protein
EBA25_RS08550	COG3209	COG3209 Rhs family protein
EBA25_RS08675	COG0632	four-way junction helicase activity
EBA25_RS08685	COG2255	four-way junction helicase activity
EBA25_RS08690	COG0824	Thioesterase
EBA25_RS08700	COG0848	biopolymer transport protein
EBA25_RS08715	COG2885	chlorophyll binding
EBA25_RS08725	COG0602	queuosine metabolic process
EBA25_RS08735	COG1187	pseudouridine synthase activity
EBA25_RS08795	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EBA25_RS08820	COG0514	ATP-dependent DNA helicase (RecQ)
EBA25_RS08830	COG0783	Belongs to the Dps family
EBA25_RS08835	COG1643	Atp-dependent helicase
EBA25_RS08890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA25_RS08900	COG1215	transferase activity, transferring glycosyl groups
EBA25_RS08905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EBA25_RS08915	COG1199	ATP-dependent helicase activity
EBA25_RS08925	COG1397	ADP-ribosylglycohydrolase
EBA25_RS08935	COG0189	ligase activity
EBA25_RS08950	COG0835	chemotaxis
EBA25_RS08955	COG0840	transmembrane signaling receptor activity
EBA25_RS08960	COG0643	Histidine kinase
EBA25_RS08960	COG2198	Histidine kinase
EBA25_RS08960	COG0784	Response regulator, receiver
EBA25_RS09005	COG1446	asparaginase
EBA25_RS09010	COG3142	Participates in the control of copper homeostasis
EBA25_RS09065	COG3537	Alpha-1,2-mannosidase
EBA25_RS09135	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA25_RS09155	COG3858	chitin binding
EBA25_RS09155	COG1388	LysM domain
EBA25_RS09170	COG0837	glucose binding
EBA25_RS09175	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EBA25_RS09185	COG0494	nUDIX hydrolase
EBA25_RS09195	COG3956	TIGRFAM MazG family protein
EBA25_RS09210	COG0330	HflC and HflK could
EBA25_RS09225	COG0509	glycine decarboxylation via glycine cleavage system
EBA25_RS09260	COG1960	acyl-CoA dehydrogenase activity
EBA25_RS09270	COG1309	transcriptional regulator
EBA25_RS09275	COG4771	TonB-dependent receptor
EBA25_RS09285	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EBA25_RS09295	COG0463	Glycosyl transferase, family 2
EBA25_RS09315	COG1272	protein, Hemolysin III
EBA25_RS09325	COG0739	heme binding
EBA25_RS09330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA25_RS09335	COG0626	cystathionine gamma-synthase activity
EBA25_RS09340	COG0527	aspartate kinase activity
EBA25_RS09340	COG0460	homoserine dehydrogenase
EBA25_RS09345	COG1760	l-serine dehydratase
EBA25_RS09360	COG2353	YceI-like domain
EBA25_RS09370	COG2353	YceI-like domain
EBA25_RS09425	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EBA25_RS09445	COG1960	acyl-CoA dehydrogenase activity
EBA25_RS09450	COG1024	Enoyl-CoA hydratase
EBA25_RS09470	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA25_RS09470	COG1024	Enoyl-CoA hydratase
EBA25_RS09485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA25_RS09515	COG1381	Involved in DNA repair and RecF pathway recombination
EBA25_RS09530	COG2954	triphosphatase activity
EBA25_RS09535	COG2954	triphosphatase activity
EBA25_RS09550	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EBA25_RS09555	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EBA25_RS09560	COG3046	protein related to deoxyribodipyrimidine photolyase
EBA25_RS09570	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EBA25_RS09575	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EBA25_RS09580	COG1278	Cold shock
EBA25_RS09600	COG1201	RNA secondary structure unwinding
EBA25_RS09605	COG1793	dna ligase
EBA25_RS09615	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EBA25_RS09615	COG1793	dna ligase
EBA25_RS09645	COG0183	Belongs to the thiolase family
EBA25_RS09670	COG1451	nucleotide metabolic process
EBA25_RS09685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EBA25_RS09730	COG1047	Peptidyl-prolyl cis-trans
EBA25_RS09745	COG2824	Alkylphosphonate utilization operon protein PhnA
EBA25_RS09760	COG1902	pentaerythritol trinitrate reductase activity
EBA25_RS09765	COG2814	Major facilitator Superfamily
EBA25_RS09820	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EBA25_RS09820	COG0392	lysyltransferase activity
EBA25_RS09830	COG0251	oxidation-reduction process
EBA25_RS09835	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA25_RS09850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA25_RS09875	COG1595	DNA-templated transcription, initiation
EBA25_RS09895	COG2878	Part of a membrane complex involved in electron transport
EBA25_RS09905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBA25_RS09905	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBA25_RS09910	COG3039	Transposase
EBA25_RS09930	COG0833	amino acid
EBA25_RS09935	COG2040	homocysteine
EBA25_RS09950	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA25_RS09990	COG0529	Catalyzes the synthesis of activated sulfate
EBA25_RS09990	COG2895	sulfate adenylyltransferase (ATP) activity
EBA25_RS10035	COG1981	membrane
EBA25_RS10060	COG1131	(ABC) transporter
EBA25_RS10065	COG4771	TonB-dependent receptor
EBA25_RS10075	COG0825	malonyl-CoA metabolic process
EBA25_RS10095	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBA25_RS10100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBA25_RS10120	COG0750	zinc metalloprotease
EBA25_RS10130	COG0575	Belongs to the CDS family
EBA25_RS10140	COG0233	cytoplasmic translational termination
EBA25_RS10155	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EBA25_RS10215	COG1393	Belongs to the ArsC family
EBA25_RS10230	COG0367	asparagine synthase
EBA25_RS10240	COG4774	siderophore transport
EBA25_RS10320	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EBA25_RS10330	COG1960	acyl-CoA dehydrogenase activity
EBA25_RS10345	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EBA25_RS10355	COG2914	Belongs to the UPF0125 (RnfH) family
EBA25_RS10365	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA25_RS10375	COG0497	DNA recombination
EBA25_RS10385	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EBA25_RS10395	COG0484	heat shock protein binding
EBA25_RS10405	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EBA25_RS10410	COG0287	Prephenate dehydrogenase
EBA25_RS10410	COG1605	Chorismate mutase
EBA25_RS10430	COG0583	DNA-binding transcription factor activity
EBA25_RS10445	COG1132	(ABC) transporter
EBA25_RS10480	COG2850	peptidyl-arginine hydroxylation
EBA25_RS10560	COG1131	(ABC) transporter
EBA25_RS10565	COG1725	Transcriptional regulator
EBA25_RS10575	COG0386	Belongs to the glutathione peroxidase family
EBA25_RS10590	COG2900	Belongs to the SlyX family
EBA25_RS10605	COG1609	Transcriptional regulator
EBA25_RS10615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA25_RS10625	COG0646	methionine synthase
EBA25_RS10625	COG1410	methionine synthase
EBA25_RS10630	COG1410	methionine synthase
EBA25_RS10630	COG0646	methionine synthase
EBA25_RS10635	COG2226	methyltransferase
EBA25_RS10640	COG1960	acyl-CoA dehydrogenase activity
EBA25_RS10670	COG0557	exoribonuclease II activity
EBA25_RS10690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA25_RS10710	COG3039	Transposase
EBA25_RS10735	COG3328	transposase activity
EBA25_RS10745	COG1278	Cold shock
EBA25_RS10760	COG3039	Transposase
EBA25_RS10765	COG3039	Transposase
EBA25_RS10815	COG3039	Transposase
EBA25_RS10825	COG0583	DNA-binding transcription factor activity
EBA25_RS10920	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EBA25_RS10930	COG0531	amino acid
EBA25_RS10935	COG0531	amino acid
EBA25_RS10945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EBA25_RS10950	COG0277	FAD linked oxidase domain protein
EBA25_RS11015	COG0436	Aminotransferase
EBA25_RS11040	COG1187	pseudouridine synthase activity
EBA25_RS11045	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EBA25_RS11050	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EBA25_RS11055	COG2350	Protein conserved in bacteria
EBA25_RS11085	COG1175	transmembrane transport
EBA25_RS11090	COG0395	ABC-type sugar transport system, permease component
EBA25_RS11115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA25_RS11125	COG2957	Belongs to the agmatine deiminase family
EBA25_RS11140	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EBA25_RS11145	COG0539	negative regulation of cytoplasmic translation
EBA25_RS11150	COG0776	regulation of translation
EBA25_RS11160	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EBA25_RS11165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA25_RS11175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EBA25_RS11195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EBA25_RS11210	COG3002	Belongs to the UPF0753 family
EBA25_RS11215	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA25_RS11220	COG0583	DNA-binding transcription factor activity
EBA25_RS11250	COG0583	DNA-binding transcription factor activity
EBA25_RS11255	COG0583	DNA-binding transcription factor activity
EBA25_RS11275	COG1914	H( )-stimulated, divalent metal cation uptake system
EBA25_RS11295	COG0668	transmembrane transport
EBA25_RS11350	COG1028	Short-chain dehydrogenase reductase Sdr
EBA25_RS11355	COG1183	phosphatidylcholine synthase activity
EBA25_RS11365	COG3243	poly(R)-hydroxyalkanoic acid synthase
EBA25_RS11380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA25_RS11380	COG0723	plastoquinol--plastocyanin reductase activity
EBA25_RS11390	COG2183	response to ionizing radiation
EBA25_RS11405	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EBA25_RS11420	COG0671	phosphoesterase, PA-phosphatase related
EBA25_RS11445	COG1794	racemase activity, acting on amino acids and derivatives
EBA25_RS11450	COG0697	spore germination
EBA25_RS11455	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EBA25_RS11475	COG1012	belongs to the aldehyde dehydrogenase family
EBA25_RS11510	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EBA25_RS11530	COG0124	histidyl-tRNA synthetase
EBA25_RS11550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EBA25_RS11565	COG0131	Imidazoleglycerol-phosphate dehydratase
EBA25_RS11565	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EBA25_RS11575	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EBA25_RS11585	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EBA25_RS11585	COG0140	phosphoribosyl-ATP diphosphatase activity
EBA25_RS11625	COG0653	protein targeting
EBA25_RS11730	COG2801	Transposase and inactivated derivatives
EBA25_RS11785	COG3328	transposase activity
EBA25_RS11820	COG0322	excinuclease ABC activity
EBA25_RS11830	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBA25_RS11840	COG1663	tetraacyldisaccharide 4'-kinase activity
EBA25_RS11855	COG0811	peptide transport
EBA25_RS11880	COG4591	ABC-type transport system involved in lipoprotein release permease component
EBA25_RS11895	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EBA25_RS11910	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EBA25_RS11925	COG0354	folic acid binding
EBA25_RS11940	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA25_RS11950	COG0363	glucosamine-6-phosphate deaminase activity
EBA25_RS11955	COG0129	dihydroxy-acid dehydratase activity
EBA25_RS11960	COG0800	Aldolase
EBA25_RS12075	COG0386	Belongs to the glutathione peroxidase family
EBA25_RS12165	COG2203	Gaf domain
EBA25_RS12165	COG3706	GGDEF domain
EBA25_RS12165	COG4251	negative regulation of phosphorylation
EBA25_RS12165	COG5001	Diguanylate cyclase
EBA25_RS12185	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA25_RS12235	COG0617	tRNA 3'-terminal CCA addition
EBA25_RS12245	COG1469	GTP cyclohydrolase I activity
EBA25_RS12250	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA25_RS12305	COG4566	intracellular signal transduction
EBA25_RS12340	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EBA25_RS12345	COG0077	Prephenate dehydratase
EBA25_RS12345	COG1605	Chorismate mutase
EBA25_RS12355	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EBA25_RS12400	COG1228	amidohydrolase
EBA25_RS12405	COG2986	histidine ammonia-lyase
EBA25_RS12415	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EBA25_RS12440	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EBA25_RS12455	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EBA25_RS12470	COG3115	cell septum assembly
EBA25_RS12480	COG0359	binds to the 23S rRNA
EBA25_RS12490	COG0360	Binds together with S18 to 16S ribosomal RNA
EBA25_RS12495	COG0316	Belongs to the HesB IscA family
EBA25_RS12530	COG0288	reversible hydration of carbon dioxide
EBA25_RS12555	COG2925	Exonuclease
EBA25_RS12565	COG0667	Aldo Keto reductase
EBA25_RS12590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBA25_RS12590	COG0116	Belongs to the methyltransferase superfamily
EBA25_RS12635	COG0494	nUDIX hydrolase
EBA25_RS12645	COG1024	Enoyl-CoA hydratase
EBA25_RS12655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EBA25_RS12670	COG3039	Transposase
EBA25_RS12710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EBA25_RS12715	COG0573	inorganic phosphate transmembrane transporter activity
EBA25_RS12730	COG0704	Plays a role in the regulation of phosphate uptake
EBA25_RS12740	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA25_RS12775	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBA25_RS12780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBA25_RS12785	COG1862	Preprotein translocase
EBA25_RS12790	COG0343	queuine tRNA-ribosyltransferase activity
EBA25_RS12875	COG0405	Gamma-glutamyltransferase
EBA25_RS12880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EBA25_RS12895	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EBA25_RS12900	COG0742	ribosomal rna small subunit methyltransferase
EBA25_RS12920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EBA25_RS12955	COG3039	Transposase
EBA25_RS12985	COG0303	'Molybdopterin
EBA25_RS12995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA25_RS13005	COG1426	Protein conserved in bacteria
EBA25_RS13015	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EBA25_RS13030	COG1024	Enoyl-CoA hydratase
EBA25_RS13030	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA25_RS13035	COG0183	Belongs to the thiolase family
EBA25_RS13040	COG0038	chloride channel
EBA25_RS13060	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EBA25_RS13085	COG1674	ftsk spoiiie
EBA25_RS13090	COG0492	ferredoxin-NADP+ reductase activity
EBA25_RS13115	COG0542	response to heat
EBA25_RS13130	COG0482	sulfurtransferase activity
EBA25_RS13155	COG5001	Diguanylate cyclase
EBA25_RS13160	COG4585	Histidine kinase
EBA25_RS13170	COG5002	protein histidine kinase activity
EBA25_RS13190	COG0784	Response regulator, receiver
EBA25_RS13190	COG0835	chemotaxis
EBA25_RS13200	COG1558	bacterial-type flagellum-dependent cell motility
EBA25_RS13205	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EBA25_RS13215	COG4787	bacterial-type flagellum-dependent cell motility
EBA25_RS13255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EBA25_RS13260	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EBA25_RS13290	COG2201	protein-glutamate methylesterase activity
EBA25_RS13310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA25_RS13320	COG1028	Short-chain dehydrogenase reductase Sdr
EBA25_RS13355	COG1677	Flagellar hook-basal body complex protein FliE
EBA25_RS13405	COG3190	flagellar
EBA25_RS13425	COG1684	flagellar biosynthetic protein fliR
EBA25_RS13480	COG2198	Histidine kinase
EBA25_RS13480	COG0643	Histidine kinase
EBA25_RS13480	COG0784	Response regulator, receiver
EBA25_RS13525	COG3039	Transposase
EBA25_RS13605	COG3039	Transposase
EBA25_RS13620	COG4988	ABC transporter
EBA25_RS13635	COG3039	Transposase
EBA25_RS13670	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EBA25_RS13690	COG0165	Argininosuccinate lyase
EBA25_RS13705	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EBA25_RS13710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA25_RS13720	COG0137	argininosuccinate synthase activity
EBA25_RS13725	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EBA25_RS13740	COG2166	iron-sulfur cluster assembly
EBA25_RS13765	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EBA25_RS13805	COG3039	Transposase
EBA25_RS13820	COG4677	pectinesterase activity
EBA25_RS13845	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EBA25_RS13850	COG0402	S-adenosylhomocysteine deaminase activity
EBA25_RS13865	COG1509	lysine 2,3-aminomutase activity
EBA25_RS13870	COG5001	Diguanylate cyclase
EBA25_RS13870	COG3300	MHYT domain
EBA25_RS13885	COG0483	inositol monophosphate 1-phosphatase activity
EBA25_RS13890	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA25_RS13915	COG0488	(ABC) transporter
EBA25_RS13920	COG0513	Belongs to the DEAD box helicase family
EBA25_RS13930	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EBA25_RS13940	COG0625	glutathione transferase activity
EBA25_RS13950	COG1671	Belongs to the UPF0178 family
EBA25_RS13955	COG4681	YaeQ
EBA25_RS13960	COG2081	HI0933 family
EBA25_RS13980	COG1028	Short-chain dehydrogenase reductase Sdr
EBA25_RS14005	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EBA25_RS14010	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA25_RS14015	COG0802	atpase or kinase
EBA25_RS14020	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EBA25_RS14020	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EBA25_RS14025	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA25_RS14050	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA25_RS14135	COG3328	transposase activity
EBA25_RS14180	COG2969	positive regulation of protein catabolic process
EBA25_RS14185	COG0625	glutathione transferase activity
EBA25_RS14190	COG2857	Cytochrome c1
EBA25_RS14195	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EBA25_RS14200	COG0723	plastoquinol--plastocyanin reductase activity
EBA25_RS14210	COG0741	lytic transglycosylase activity
EBA25_RS14240	COG1702	phosphate starvation-inducible protein PhoH
EBA25_RS14260	COG4535	Mg2 and Co2 transporter CorC
EBA25_RS14275	COG1012	belongs to the aldehyde dehydrogenase family
EBA25_RS14285	COG1177	transmembrane transport
EBA25_RS14295	COG3842	ATPase activity
EBA25_RS14335	COG0174	glutamine synthetase
EBA25_RS14340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA25_RS14350	COG0477	Major facilitator Superfamily
EBA25_RS14360	COG0243	molybdopterin cofactor binding
EBA25_RS14370	COG2223	nitrite transmembrane transporter activity
EBA25_RS14380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EBA25_RS14385	COG1121	(ABC) transporter
EBA25_RS14395	COG2733	membrane
EBA25_RS14400	COG0784	Response regulator, receiver
EBA25_RS14400	COG2205	protein histidine kinase activity
EBA25_RS14400	COG5002	protein histidine kinase activity
EBA25_RS14410	COG3039	Transposase
EBA25_RS14420	COG2902	Dehydrogenase
EBA25_RS14430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA25_RS14435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA25_RS14455	COG1609	Transcriptional regulator
EBA25_RS14460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA25_RS14460	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA25_RS14465	COG1105	Belongs to the carbohydrate kinase PfkB family
EBA25_RS14470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA25_RS14470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA25_RS14485	COG3039	Transposase
EBA25_RS14650	COG3039	Transposase
EBA25_RS14680	COG4771	TonB-dependent receptor
EBA25_RS14690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA25_RS14710	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EBA25_RS14715	COG1360	Flagellar Motor Protein
EBA25_RS14725	COG0835	chemotaxis
EBA25_RS14735	COG0745	RESPONSE REGULATOR receiver
EBA25_RS14760	COG0840	transmembrane signaling receptor activity
EBA25_RS14775	COG0840	transmembrane signaling receptor activity
EBA25_RS14785	COG0840	transmembrane signaling receptor activity
EBA25_RS14795	COG0840	transmembrane signaling receptor activity
EBA25_RS14800	COG0840	transmembrane signaling receptor activity
EBA25_RS14805	COG0840	transmembrane signaling receptor activity
EBA25_RS14810	COG0840	transmembrane signaling receptor activity
EBA25_RS14830	COG0835	chemotaxis
EBA25_RS14855	COG0840	transmembrane signaling receptor activity
EBA25_RS14890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA25_RS14920	COG0318	PFAM AMP-dependent synthetase and ligase
EBA25_RS14925	COG1024	Enoyl-CoA hydratase
EBA25_RS14930	COG0784	Response regulator, receiver
EBA25_RS14930	COG2198	Histidine kinase
EBA25_RS14930	COG2205	protein histidine kinase activity
EBA25_RS15000	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EBA25_RS15010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA25_RS15015	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EBA25_RS15025	COG0505	Belongs to the CarA family
EBA25_RS15030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EBA25_RS15040	COG2258	MOSC domain
EBA25_RS15045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBA25_RS15095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EBA25_RS15115	COG0477	Major facilitator Superfamily
EBA25_RS15125	COG1070	Carbohydrate kinase
EBA25_RS15135	COG1501	Belongs to the glycosyl hydrolase 31 family
EBA25_RS15150	COG0800	Aldolase
EBA25_RS15155	COG4948	Mandelate Racemase Muconate Lactonizing
EBA25_RS15165	COG3734	2-keto-3-deoxy-galactonokinase
EBA25_RS15170	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EBA25_RS15180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA25_RS15195	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EBA25_RS15200	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EBA25_RS15210	COG0351	phosphomethylpyrimidine kinase
EBA25_RS15240	COG0583	DNA-binding transcription factor activity
EBA25_RS15245	COG1741	Belongs to the pirin family
EBA25_RS15265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EBA25_RS15270	COG0305	Participates in initiation and elongation during chromosome replication
EBA25_RS15295	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EBA25_RS15300	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EBA25_RS15305	COG2137	regulation of response to DNA damage stimulus
EBA25_RS15310	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EBA25_RS15325	COG1546	Belongs to the CinA family
EBA25_RS15330	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EBA25_RS15345	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EBA25_RS15355	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EBA25_RS15360	COG1534	Rna-binding protein
EBA25_RS15375	COG1238	metal cluster binding
EBA25_RS15380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBA25_RS15385	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EBA25_RS15390	COG2840	Smr protein MutS2
EBA25_RS15400	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EBA25_RS15415	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EBA25_RS15420	COG0148	phosphopyruvate hydratase activity
EBA25_RS15430	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EBA25_RS15435	COG0504	CTP synthase activity
EBA25_RS15460	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EBA25_RS15465	COG0306	phosphate transporter
EBA25_RS15480	COG1253	flavin adenine dinucleotide binding
EBA25_RS15495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBA25_RS15515	COG0477	Major facilitator Superfamily
EBA25_RS15525	COG1132	(ABC) transporter
EBA25_RS15530	COG1136	(ABC) transporter
EBA25_RS15550	COG0438	transferase activity, transferring glycosyl groups
EBA25_RS15560	COG2264	protein methyltransferase activity
EBA25_RS15590	COG2244	polysaccharide biosynthetic process
EBA25_RS15640	COG1595	DNA-templated transcription, initiation
EBA25_RS15655	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA25_RS15675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA25_RS15730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA25_RS15735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA25_RS15790	COG1858	cytochrome C peroxidase
EBA25_RS15830	COG0515	serine threonine protein kinase
EBA25_RS15835	COG0631	protein serine/threonine phosphatase activity
EBA25_RS15950	COG3039	Transposase
EBA25_RS15970	COG3039	Transposase
EBA25_RS16015	COG0316	Belongs to the HesB IscA family
EBA25_RS16015	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EBA25_RS16020	COG2154	pterin-4-alpha-carbinolamine dehydratase
EBA25_RS16030	COG0428	transporter
EBA25_RS16035	COG0428	transporter
EBA25_RS16040	COG3064	Membrane
EBA25_RS16050	COG1530	ribonuclease E activity
EBA25_RS16070	COG1054	Belongs to the UPF0176 family
EBA25_RS16075	COG3039	Transposase
EBA25_RS16095	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EBA25_RS16135	COG3039	Transposase
EBA25_RS16140	COG3039	Transposase
EBA25_RS16170	COG1648	precorrin-2 dehydrogenase activity
EBA25_RS16170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EBA25_RS16195	COG0746	molybdenum cofactor guanylyltransferase activity
EBA25_RS16275	COG4206	TonB-dependent receptor
EBA25_RS16305	COG4206	TonB-dependent receptor
EBA25_RS16355	COG0531	amino acid
EBA25_RS16370	COG0006	proline dipeptidase activity
EBA25_RS16380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA25_RS16395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA25_RS16400	COG3938	Belongs to the proline racemase family
EBA25_RS16410	COG0552	protein localization to endoplasmic reticulum
EBA25_RS16435	COG0784	Response regulator, receiver
EBA25_RS16435	COG4191	Histidine kinase
EBA25_RS16525	COG3040	lipid binding
EBA25_RS16565	COG0438	transferase activity, transferring glycosyl groups
EBA25_RS16575	COG0438	transferase activity, transferring glycosyl groups
EBA25_RS16580	COG0438	transferase activity, transferring glycosyl groups
EBA25_RS16650	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EBA25_RS16690	COG4969	Belongs to the N-Me-Phe pilin family
EBA25_RS16730	COG1611	Belongs to the LOG family
EBA25_RS16745	COG2095	MarC family integral membrane protein
EBA25_RS16755	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA25_RS16790	COG1185	polyribonucleotide nucleotidyltransferase activity
EBA25_RS16795	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EBA25_RS16815	COG0195	Participates in both transcription termination and antitermination
EBA25_RS16820	COG0779	Required for maturation of 30S ribosomal subunits
EBA25_RS16830	COG1007	ATP synthesis coupled electron transport
EBA25_RS16860	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EBA25_RS16865	COG1034	ATP synthesis coupled electron transport
EBA25_RS16870	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EBA25_RS16875	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EBA25_RS16880	COG0649	NAD binding
EBA25_RS16885	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA25_RS16895	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA25_RS16910	COG0149	triose-phosphate isomerase activity
EBA25_RS16965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBA25_RS16970	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EBA25_RS16995	COG0135	phosphoribosylanthranilate isomerase activity
EBA25_RS17000	COG0101	tRNA pseudouridine synthase activity
EBA25_RS17020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EBA25_RS17025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBA25_RS17030	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EBA25_RS17035	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA25_RS17090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA25_RS17100	COG0412	Dienelactone hydrolase
EBA25_RS17125	COG0717	Belongs to the dCTP deaminase family
EBA25_RS17130	COG0489	protein tyrosine kinase activity
EBA25_RS17175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA25_RS17180	COG2311	Membrane
EBA25_RS17185	COG1047	Peptidyl-prolyl cis-trans
EBA25_RS17190	COG0791	NLP P60 protein
EBA25_RS17195	COG0791	NLP P60 protein
EBA25_RS17215	COG1301	dicarboxylic acid transport
EBA25_RS17220	COG1785	Belongs to the alkaline phosphatase family
EBA25_RS17225	COG0037	tRNA processing
EBA25_RS17230	COG1722	exodeoxyribonuclease VII activity
EBA25_RS17235	COG0142	geranyltranstransferase activity
EBA25_RS17260	COG0312	modulator of DNA gyrase
EBA25_RS17265	COG3028	Belongs to the UPF0307 family
EBA25_RS17270	COG0312	modulator of DNA gyrase
EBA25_RS17280	COG3164	Protein of unknown function
EBA25_RS17295	COG2968	Membrane
EBA25_RS17320	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EBA25_RS17345	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EBA25_RS17375	COG3118	belongs to the thioredoxin family
EBA25_RS17460	COG3039	Transposase
EBA25_RS17465	COG3039	Transposase
EBA25_RS17560	COG2022	thiamine diphosphate biosynthetic process
EBA25_RS17575	COG0471	metal ion transport
EBA25_RS17575	COG3273	potassium ion transport
EBA25_RS17605	COG1970	mechanosensitive ion channel activity
EBA25_RS17630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA25_RS17660	COG0308	aminopeptidase N
EBA25_RS17665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA25_RS17680	COG2895	sulfate adenylyltransferase (ATP) activity
EBA25_RS17680	COG0529	Catalyzes the synthesis of activated sulfate
EBA25_RS17685	COG0175	sulfate reduction
EBA25_RS17690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA25_RS17695	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EBA25_RS17700	COG0175	sulfate reduction
EBA25_RS17720	COG2198	Histidine kinase
EBA25_RS17720	COG2205	protein histidine kinase activity
EBA25_RS17720	COG0784	Response regulator, receiver
EBA25_RS17765	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EBA25_RS17770	COG3588	fructose-bisphosphate aldolase
EBA25_RS17775	COG0469	pyruvate kinase activity
EBA25_RS17820	COG0753	catalase activity
EBA25_RS17845	COG3039	Transposase
EBA25_RS17865	COG1917	Cupin 2, conserved barrel domain protein
EBA25_RS17865	COG2207	Transcriptional regulator
EBA25_RS17895	COG1506	peptidase
EBA25_RS17895	COG0823	Involved in the tonB-independent uptake of proteins
EBA25_RS17920	COG3039	Transposase
EBA25_RS17925	COG1297	OPT oligopeptide transporter protein
EBA25_RS18030	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EBA25_RS18045	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
EBA25_RS18050	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
EBA25_RS18055	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EBA25_RS18075	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EBA25_RS18235	COG3179	chitinase
EBA25_RS18275	COG3179	chitinase
EBA25_RS18410	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA25_RS18465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA25_RS18475	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA25_RS18565	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EBA25_RS18590	COG2197	response regulator
EBA25_RS18595	COG4585	Histidine kinase
EBA25_RS18615	COG2894	cell division
EBA25_RS18620	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EBA25_RS18630	COG0642	Histidine kinase
EBA25_RS18635	COG0745	RESPONSE REGULATOR receiver
EBA25_RS18640	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EBA25_RS18650	COG2194	sulfuric ester hydrolase activity
EBA25_RS18680	COG3551	Protein conserved in bacteria
EBA25_RS18745	COG0203	ribosomal protein L17
EBA25_RS18755	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EBA25_RS18760	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EBA25_RS18770	COG0201	protein transport
EBA25_RS18780	COG1841	ribosomal large subunit assembly
EBA25_RS18810	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EBA25_RS18820	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EBA25_RS18825	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EBA25_RS18830	COG0255	Belongs to the universal ribosomal protein uL29 family
EBA25_RS18835	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EBA25_RS18845	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EBA25_RS18860	COG0089	rRNA binding
EBA25_RS18865	COG0088	Forms part of the polypeptide exit tunnel
EBA25_RS18870	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EBA25_RS18875	COG0051	transcription antitermination factor activity, RNA binding
EBA25_RS18895	COG0049	tRNA binding
EBA25_RS18900	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EBA25_RS18905	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EBA25_RS18910	COG0085	RNA polymerase activity
EBA25_RS18915	COG0222	ribosome binding
EBA25_RS18920	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EBA25_RS18930	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EBA25_RS18940	COG0250	Participates in transcription elongation, termination and antitermination
EBA25_RS18945	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EBA25_RS18975	COG0012	GTP binding
EBA25_RS18980	COG0193	aminoacyl-tRNA hydrolase activity
EBA25_RS18990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EBA25_RS19005	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EBA25_RS19020	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EBA25_RS19030	COG0521	Mo-molybdopterin cofactor biosynthetic process
EBA25_RS19050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA25_RS19055	COG1295	ribonuclease BN
EBA25_RS19085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EBA25_RS19095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EBA25_RS19125	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EBA25_RS19150	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBA25_RS19165	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA25_RS19165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA25_RS19215	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA25_RS19225	COG3634	alkyl hydroperoxide reductase activity
EBA25_RS19230	COG0583	DNA-binding transcription factor activity
EBA25_RS19240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA25_RS19320	COG4783	chaperone-mediated protein folding
EBA25_RS19335	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EBA25_RS19345	COG0438	transferase activity, transferring glycosyl groups
EBA25_RS19350	COG0671	phosphoesterase, PA-phosphatase related
EBA25_RS19355	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBA25_RS19375	COG2833	Protein of unknown function (DUF455)
EBA25_RS19395	COG0285	dihydrofolate synthase activity
EBA25_RS19405	COG0406	alpha-ribazole phosphatase activity
EBA25_RS19440	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EBA25_RS19445	COG4208	sulfate ABC transporter
EBA25_RS19450	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EBA25_RS19455	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EBA25_RS19460	COG0156	8-amino-7-oxononanoate synthase activity
EBA25_RS19490	COG0604	alcohol dehydrogenase
EBA25_RS19495	COG0446	pyridine nucleotide-disulphide oxidoreductase
EBA25_RS19495	COG1902	pentaerythritol trinitrate reductase activity
EBA25_RS19645	COG3386	PFAM SMP-30 Gluconolaconase
EBA25_RS19665	COG1024	Enoyl-CoA hydratase
EBA25_RS19675	COG0318	PFAM AMP-dependent synthetase and ligase
EBA25_RS19680	COG0583	DNA-binding transcription factor activity
EBA25_RS19720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA25_RS19725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA25_RS19735	COG2096	Adenosyltransferase
EBA25_RS19740	COG0123	including yeast histone deacetylase and acetoin utilization protein
EBA25_RS19755	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EBA25_RS19765	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EBA25_RS19770	COG2967	ApaG domain
EBA25_RS19795	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EBA25_RS19815	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EBA25_RS19830	COG0642	Histidine kinase
EBA25_RS19845	COG4181	ATPase activity
EBA25_RS19855	COG2175	clavaminate synthase activity
EBA25_RS19865	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EBA25_RS19905	COG0667	Aldo Keto reductase
EBA25_RS19915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EBA25_RS19920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA25_RS19935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA25_RS19950	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EBA25_RS20005	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EBA25_RS20010	COG2226	methyltransferase
EBA25_RS20065	COG0604	alcohol dehydrogenase
EBA25_RS20065	COG1028	Short-chain dehydrogenase reductase Sdr
EBA25_RS20065	COG3321	synthase
EBA25_RS20080	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EBA25_RS20095	COG0494	nUDIX hydrolase
EBA25_RS20110	COG4942	peptidase
EBA25_RS20110	COG1388	LysM domain
EBA25_RS20120	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EBA25_RS20135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EBA25_RS20140	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA25_RS20145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBA25_RS20160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA25_RS20165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EBA25_RS20180	COG3116	cell division
EBA25_RS20185	COG0275	rRNA processing
EBA25_RS20220	COG0792	nuclease activity
EBA25_RS20225	COG1988	membrane-bound metal-dependent
EBA25_RS20230	COG0277	FAD linked oxidase domain protein
EBA25_RS20235	COG0745	RESPONSE REGULATOR receiver
EBA25_RS20240	COG2205	protein histidine kinase activity
EBA25_RS20250	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EBA25_RS20255	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EBA25_RS20280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EBA25_RS20285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBA25_RS20290	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EBA25_RS20310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA25_RS20310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA25_RS20330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EBA25_RS20350	COG0488	(ABC) transporter
EBA25_RS20400	COG2205	protein histidine kinase activity
EBA25_RS20440	COG2205	protein histidine kinase activity
EBA25_RS20460	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EBA25_RS20495	COG3039	Transposase
EBA25_RS20500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EBA25_RS20515	COG3039	Transposase
EBA25_RS20570	COG3039	Transposase
EBA25_RS20620	COG0726	polysaccharide deacetylase
EBA25_RS20620	COG1649	PFAM Uncharacterised BCR, COG1649
EBA25_RS20625	COG1215	transferase activity, transferring glycosyl groups
EBA25_RS20635	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EBA25_RS20640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA25_RS20645	COG1609	Transcriptional regulator
EBA25_RS20655	COG2188	Transcriptional regulator
EBA25_RS20670	COG3250	beta-galactosidase activity
EBA25_RS20725	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EBA25_RS20730	COG4191	Histidine kinase
EBA25_RS20735	COG0784	Response regulator, receiver
EBA25_RS20740	COG4251	negative regulation of phosphorylation
EBA25_RS20745	COG2823	Periplasmic or secreted lipoprotein
EBA25_RS20750	COG0673	inositol 2-dehydrogenase activity
EBA25_RS20755	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EBA25_RS20790	COG1056	cytidyltransferase-related domain
EBA25_RS20790	COG1051	belongs to the nudix hydrolase family
EBA25_RS20825	COG2921	Belongs to the UPF0250 family
EBA25_RS20840	COG1686	Belongs to the peptidase S11 family
EBA25_RS20845	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EBA25_RS20850	COG2951	lytic endotransglycosylase activity
EBA25_RS20910	COG0772	Belongs to the SEDS family
EBA25_RS20925	COG1792	Involved in formation and maintenance of cell shape
EBA25_RS20930	COG1077	Cell shape determining protein MreB Mrl
EBA25_RS20935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA25_RS20940	COG3039	Transposase
EBA25_RS20990	COG2199	diguanylate cyclase activity
EBA25_RS20995	COG0308	aminopeptidase N
EBA25_RS21025	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EBA25_RS21055	COG0436	Aminotransferase
EBA25_RS21070	COG1505	serine-type exopeptidase activity
EBA25_RS21095	COG0181	hydroxymethylbilane synthase activity
EBA25_RS21105	COG3275	phosphorelay sensor kinase activity
EBA25_RS21150	COG0659	secondary active sulfate transmembrane transporter activity
EBA25_RS21155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA25_RS21155	COG5297	Belongs to the glycosyl hydrolase family 6
EBA25_RS21230	COG0598	Magnesium transport protein CorA
EBA25_RS21240	COG1113	amino acid transport
EBA25_RS21250	COG5297	Belongs to the glycosyl hydrolase family 6
EBA25_RS21255	COG4305	rare lipoprotein A
EBA25_RS21260	COG0697	spore germination
EBA25_RS21320	COG4221	oxidoreductase activity
EBA25_RS21350	COG0456	acetyltransferase
EBA25_RS21360	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EBA25_RS21395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA25_RS21395	COG2111	Na H antiporter
EBA25_RS21400	COG1006	Multisubunit Na H antiporter MnhC subunit
EBA25_RS21405	COG0651	ATP synthesis coupled electron transport
EBA25_RS21415	COG2212	antiporter activity
EBA25_RS21420	COG1320	monovalent cation:proton antiporter activity
EBA25_RS21435	COG3039	Transposase
EBA25_RS21440	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EBA25_RS21460	COG3104	oligopeptide transport
EBA25_RS21465	COG3483	tryptophan 2,3-dioxygenase activity
EBA25_RS21475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EBA25_RS21510	COG0183	Belongs to the thiolase family
EBA25_RS21565	COG3039	Transposase
EBA25_RS21600	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EBA25_RS21605	COG3023	N-Acetylmuramoyl-L-alanine amidase
EBA25_RS21615	COG4948	Mandelate Racemase Muconate Lactonizing
EBA25_RS21655	COG0531	amino acid
EBA25_RS21690	COG4682	membrane
EBA25_RS21695	COG3039	Transposase
EBA25_RS21700	COG2133	pyrroloquinoline quinone binding
EBA25_RS21740	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EBA25_RS21745	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EBA25_RS21755	COG1610	YqeY-like protein
EBA25_RS21770	COG1295	ribonuclease BN
EBA25_RS21775	COG0358	DNA primase activity
EBA25_RS21840	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EBA25_RS21855	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EBA25_RS21905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EBA25_RS21910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EBA25_RS21915	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EBA25_RS21925	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EBA25_RS21930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EBA25_RS21945	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EBA25_RS22025	COG3039	Transposase
EBA25_RS22040	COG3328	transposase activity
EBA25_RS22055	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EBA25_RS22055	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EBA25_RS22065	COG1473	amidohydrolase
EBA25_RS22070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA25_RS22075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA25_RS22090	COG5383	Protein conserved in bacteria
EBA25_RS22135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EBA25_RS22140	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EBA25_RS22155	COG0028	Belongs to the TPP enzyme family
EBA25_RS22160	COG4191	Histidine kinase
EBA25_RS22185	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EBA25_RS22200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA25_RS22205	COG3177	Filamentation induced by cAMP protein fic
EBA25_RS22220	COG0596	Alpha beta hydrolase
EBA25_RS22225	COG0727	PFAM Uncharacterised protein family (UPF0153)
EBA25_RS22230	COG0318	PFAM AMP-dependent synthetase and ligase
EBA25_RS22235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EBA25_RS22290	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EBA25_RS22300	COG0129	dihydroxy-acid dehydratase activity
EBA25_RS22340	COG0408	coproporphyrinogen oxidase activity
EBA25_RS22395	COG3039	Transposase
EBA25_RS22405	COG2201	protein-glutamate methylesterase activity
EBA25_RS22450	COG2353	YceI-like domain
EBA25_RS22480	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA25_RS22495	COG3386	PFAM SMP-30 Gluconolaconase
EBA25_RS22535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EBA25_RS22550	COG4771	TonB-dependent receptor
EBA25_RS22560	COG0459	protein refolding
EBA25_RS22585	COG1252	NADH dehydrogenase
EBA25_RS22595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA25_RS22600	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EBA25_RS22605	COG3437	response regulator, receiver
EBA25_RS22610	COG2177	Part of the ABC transporter FtsEX involved in
EBA25_RS22615	COG2884	Cell division ATP-binding protein ftsE
EBA25_RS22625	COG3118	belongs to the thioredoxin family
EBA25_RS22630	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EBA25_RS22645	COG0729	surface antigen
EBA25_RS22650	COG2911	Protein conserved in bacteria
EBA25_RS22685	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBA25_RS22700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBA25_RS22760	COG1733	regulation of RNA biosynthetic process
EBA25_RS22765	COG0702	epimerase
EBA25_RS22800	COG0583	DNA-binding transcription factor activity
EBA25_RS22805	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA25_RS22825	COG0745	RESPONSE REGULATOR receiver
EBA25_RS22855	COG1902	pentaerythritol trinitrate reductase activity
EBA25_RS22860	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EBA25_RS22870	COG2814	Major facilitator Superfamily
EBA25_RS22875	COG0583	DNA-binding transcription factor activity
EBA25_RS22895	COG0084	hydrolase, TatD family'
EBA25_RS22945	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EBA25_RS22965	COG2072	flavoprotein involved in K transport
EBA25_RS23020	COG4770	biotin carboxylase activity
EBA25_RS23025	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EBA25_RS23030	COG1960	acyl-CoA dehydrogenase activity
EBA25_RS23080	COG0523	cobalamin synthesis protein
EBA25_RS23090	COG0697	spore germination
EBA25_RS23100	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EBA25_RS23115	COG4771	TonB-dependent receptor
EBA25_RS23120	COG0457	Tetratricopeptide repeat
EBA25_RS23135	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA25_RS23160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA25_RS23160	COG0519	Catalyzes the synthesis of GMP from XMP
EBA25_RS23170	COG0805	protein transport
EBA25_RS23180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA25_RS23190	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EBA25_RS23240	COG3661	Belongs to the glycosyl hydrolase 67 family
EBA25_RS23250	COG4948	Mandelate Racemase Muconate Lactonizing
EBA25_RS23260	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA25_RS23265	COG0246	Mannitol dehydrogenase
EBA25_RS23290	COG3693	PFAM glycoside hydrolase, family 10
EBA25_RS23315	COG2211	Major facilitator Superfamily
EBA25_RS23360	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EBA25_RS23410	COG1846	Transcriptional regulator
EBA25_RS23415	COG1764	response to oxidative stress
EBA25_RS23515	COG3549	Plasmid maintenance system killer
EBA25_RS23525	COG1074	ATP-dependent DNA helicase activity
EBA25_RS23530	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EBA25_RS23540	COG1196	nuclear chromosome segregation
EBA25_RS23580	COG2032	superoxide dismutase activity
EBA25_RS23585	COG2032	superoxide dismutase activity
EBA25_RS23590	COG2204	response regulator
EBA25_RS23595	COG3852	Histidine kinase
EBA25_RS23600	COG0004	ammonium transporteR
EBA25_RS23605	COG0347	Belongs to the P(II) protein family
EBA25_RS23610	COG0174	glutamine synthetase
EBA25_RS23615	COG1968	undecaprenyl-diphosphatase activity
EBA25_RS23660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA25_RS23670	COG2062	phosphohistidine phosphatase, SixA
EBA25_RS23675	COG0489	protein tyrosine kinase activity
EBA25_RS23695	COG1396	sequence-specific DNA binding
EBA25_RS23700	COG3550	peptidyl-serine autophosphorylation
EBA25_RS23705	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EBA25_RS23710	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA25_RS23725	COG0517	IMP dehydrogenase activity
EBA25_RS23725	COG1125	glycine betaine transport
EBA25_RS23740	COG1119	ATPase activity
EBA25_RS23750	COG1752	Esterase of the alpha-beta hydrolase superfamily
EBA25_RS23765	COG3039	Transposase
EBA25_RS23790	COG0656	L-ascorbic acid biosynthetic process
EBA25_RS23795	COG2130	NADP-dependent
EBA25_RS23800	COG0667	Aldo Keto reductase
EBA25_RS23810	COG1187	pseudouridine synthase activity
EBA25_RS23825	COG1643	Atp-dependent helicase
EBA25_RS23830	COG4807	Protein conserved in bacteria
EBA25_RS23835	COG4948	Mandelate Racemase Muconate Lactonizing
EBA25_RS23845	COG0179	Fumarylacetoacetate (FAA) hydrolase
EBA25_RS23850	COG1028	Short-chain dehydrogenase reductase Sdr
EBA25_RS23870	COG3507	Belongs to the glycosyl hydrolase 43 family
EBA25_RS23910	COG3162	membrane
EBA25_RS23915	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EBA25_RS23930	COG0708	Exodeoxyribonuclease III
EBA25_RS23945	COG2091	lysine biosynthetic process via aminoadipic acid
EBA25_RS23955	COG3540	Alkaline phosphatase
EBA25_RS23985	COG2159	amidohydrolase
EBA25_RS24010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EBA25_RS24015	COG0583	DNA-binding transcription factor activity
EBA25_RS24020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA25_RS24040	COG0210	DNA helicase
EBA25_RS24055	COG0531	amino acid
EBA25_RS24065	COG1322	Protein conserved in bacteria
EBA25_RS24075	COG0386	Belongs to the glutathione peroxidase family
EBA25_RS24130	COG0793	Belongs to the peptidase S41A family
EBA25_RS24135	COG4942	peptidase
EBA25_RS24145	COG2234	aminopeptidase activity
EBA25_RS24195	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EBA25_RS24200	COG0302	gtp cyclohydrolase
EBA25_RS24225	COG0477	Major facilitator Superfamily
EBA25_RS24330	COG1929	Belongs to the glycerate kinase type-1 family
EBA25_RS24335	COG2271	Major facilitator Superfamily
EBA25_RS24350	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBA25_RS24360	COG0861	Integral membrane protein TerC family
EBA25_RS24370	COG0584	glycerophosphoryl diester phosphodiesterase
EBA25_RS24380	COG0671	phosphoesterase, PA-phosphatase related
EBA25_RS24390	COG0726	polysaccharide deacetylase