locus-tag	class	description
B9W05_RS00020	COG4191	Histidine kinase
B9W05_RS00045	COG0280	phosphate acetyltransferase
B9W05_RS00045	COG0281	malic enzyme
B9W05_RS00080	COG0352	thiamine-phosphate diphosphorylase activity
B9W05_RS00085	COG1773	rubredoxin
B9W05_RS00090	COG2912	Transglutaminase-like superfamily
B9W05_RS00110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B9W05_RS00135	COG0006	proline dipeptidase activity
B9W05_RS00170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B9W05_RS00185	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B9W05_RS00190	COG1561	YicC-like family, N-terminal region
B9W05_RS00215	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B9W05_RS00225	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B9W05_RS00250	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B9W05_RS00300	COG0714	Associated with various cellular activities
B9W05_RS00320	COG2304	oxidoreductase activity
B9W05_RS00340	COG1301	dicarboxylic acid transport
B9W05_RS00345	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B9W05_RS00350	COG4773	Receptor
B9W05_RS00355	COG0739	heme binding
B9W05_RS00360	COG1376	ErfK ybiS ycfS ynhG family protein
B9W05_RS00385	COG1022	Amp-dependent synthetase and ligase
B9W05_RS00395	COG1028	Short-chain dehydrogenase reductase Sdr
B9W05_RS00410	COG0642	Histidine kinase
B9W05_RS00430	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
B9W05_RS00435	COG4149	molybdate abc transporter
B9W05_RS00440	COG0725	ABC transporter, periplasmic molybdate-binding protein
B9W05_RS00445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9W05_RS00445	COG3453	Protein conserved in bacteria
B9W05_RS00480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B9W05_RS00500	COG2205	protein histidine kinase activity
B9W05_RS00505	COG0745	RESPONSE REGULATOR receiver
B9W05_RS00520	COG3039	Transposase
B9W05_RS00555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B9W05_RS00560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B9W05_RS00605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B9W05_RS00670	COG2201	protein-glutamate methylesterase activity
B9W05_RS00705	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B9W05_RS00715	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B9W05_RS00720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B9W05_RS00735	COG1842	Phage shock protein A
B9W05_RS00760	COG0754	glutathionylspermidine amidase activity
B9W05_RS00830	COG0531	amino acid
B9W05_RS00835	COG2197	response regulator
B9W05_RS00850	COG1113	amino acid transport
B9W05_RS00870	COG1271	oxidase subunit
B9W05_RS00875	COG1294	oxidase, subunit
B9W05_RS00885	COG2239	Acts as a magnesium transporter
B9W05_RS00895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B9W05_RS00900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9W05_RS00910	COG1660	Displays ATPase and GTPase activities
B9W05_RS00915	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B9W05_RS00920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9W05_RS00935	COG1137	ATPase activity
B9W05_RS00940	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
B9W05_RS00950	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B9W05_RS00960	COG0271	Belongs to the BolA IbaG family
B9W05_RS00970	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B9W05_RS00990	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B9W05_RS01005	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B9W05_RS01015	COG0628	permease
B9W05_RS01025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B9W05_RS01030	COG3178	'Phosphotransferase
B9W05_RS01045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9W05_RS01100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B9W05_RS01110	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B9W05_RS01135	COG0228	four-way junction DNA binding
B9W05_RS01140	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B9W05_RS01145	COG0336	Belongs to the RNA methyltransferase TrmD family
B9W05_RS01160	COG0534	Mate efflux family protein
B9W05_RS01200	COG0542	response to heat
B9W05_RS01240	COG4206	TonB-dependent receptor
B9W05_RS01300	COG0019	diaminopimelate decarboxylase activity
B9W05_RS01315	COG4264	IucA IucC family
B9W05_RS01325	COG4772	TonB-dependent receptor
B9W05_RS01340	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B9W05_RS01340	COG4651	solute:proton antiporter activity
B9W05_RS01375	COG0488	(ABC) transporter
B9W05_RS01400	COG2755	lipolytic protein G-D-S-L family
B9W05_RS01400	COG0657	acetylesterase activity
B9W05_RS01420	COG2207	Transcriptional regulator
B9W05_RS01425	COG0326	Molecular chaperone. Has ATPase activity
B9W05_RS01455	COG3328	transposase activity
B9W05_RS01460	COG0174	glutamine synthetase
B9W05_RS01465	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
B9W05_RS01475	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B9W05_RS01490	COG3039	Transposase
B9W05_RS01500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B9W05_RS01530	COG2146	nitrite reductase [NAD(P)H] activity
B9W05_RS01545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B9W05_RS01550	COG0719	Fe-S assembly protein
B9W05_RS01555	COG0396	ATPase activity
B9W05_RS01560	COG0719	Fe-S assembly protein
B9W05_RS01565	COG1959	2 iron, 2 sulfur cluster binding
B9W05_RS01585	COG0693	protein deglycase activity
B9W05_RS01630	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B9W05_RS01665	COG0519	Catalyzes the synthesis of GMP from XMP
B9W05_RS01675	COG1678	Uncharacterized ACR, COG1678
B9W05_RS01680	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B9W05_RS01695	COG1764	response to oxidative stress
B9W05_RS01705	COG0384	phenazine biosynthesis protein PhzF
B9W05_RS01715	COG0527	aspartate kinase activity
B9W05_RS01745	COG0142	geranyltranstransferase activity
B9W05_RS01750	COG0629	single-stranded DNA binding
B9W05_RS01790	COG2879	small protein
B9W05_RS01795	COG1966	Carbon starvation protein
B9W05_RS01800	COG1741	Belongs to the pirin family
B9W05_RS01915	COG1741	Belongs to the pirin family
B9W05_RS01925	COG1515	deoxyribonuclease V activity
B9W05_RS01945	COG3590	peptidase
B9W05_RS01960	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B9W05_RS01965	COG2202	Pas domain
B9W05_RS01965	COG2200	EAL domain
B9W05_RS01965	COG2199	diguanylate cyclase activity
B9W05_RS01970	COG0835	chemotaxis
B9W05_RS01975	COG0840	transmembrane signaling receptor activity
B9W05_RS01980	COG0643	Histidine kinase
B9W05_RS01980	COG2198	Histidine kinase
B9W05_RS01990	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B9W05_RS02000	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B9W05_RS02020	COG2205	protein histidine kinase activity
B9W05_RS02045	COG3039	Transposase
B9W05_RS02070	COG3039	Transposase
B9W05_RS02075	COG3039	Transposase
B9W05_RS02110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B9W05_RS02115	COG0735	belongs to the Fur family
B9W05_RS02175	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B9W05_RS02180	COG0084	hydrolase, TatD family'
B9W05_RS02195	COG1960	acyl-CoA dehydrogenase activity
B9W05_RS02210	COG0367	asparagine synthase
B9W05_RS02220	COG0305	Participates in initiation and elongation during chromosome replication
B9W05_RS02225	COG0415	Belongs to the DNA photolyase family
B9W05_RS02245	COG1028	Short-chain dehydrogenase reductase Sdr
B9W05_RS02290	COG3039	Transposase
B9W05_RS02355	COG5002	protein histidine kinase activity
B9W05_RS02355	COG5001	Diguanylate cyclase
B9W05_RS02360	COG1187	pseudouridine synthase activity
B9W05_RS02385	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B9W05_RS02395	COG0475	glutathione-regulated potassium exporter activity
B9W05_RS02400	COG5000	phosphorelay sensor kinase activity
B9W05_RS02400	COG5002	protein histidine kinase activity
B9W05_RS02405	COG0745	RESPONSE REGULATOR receiver
B9W05_RS02435	COG1132	(ABC) transporter
B9W05_RS02460	COG3039	Transposase
B9W05_RS02475	COG3039	Transposase
B9W05_RS02520	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B9W05_RS02530	COG4969	Belongs to the N-Me-Phe pilin family
B9W05_RS02535	COG2194	sulfuric ester hydrolase activity
B9W05_RS02575	COG0045	succinate-CoA ligase (ADP-forming) activity
B9W05_RS02580	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B9W05_RS02595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B9W05_RS02595	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B9W05_RS02600	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B9W05_RS02605	COG0564	pseudouridine synthase activity
B9W05_RS02630	COG3387	PFAM Glycoside hydrolase 15-related
B9W05_RS02635	COG1877	trehalose-phosphatase activity
B9W05_RS02675	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
B9W05_RS02695	COG1595	DNA-templated transcription, initiation
B9W05_RS02705	COG1946	Acyl-CoA thioesterase
B9W05_RS02720	COG0824	Thioesterase
B9W05_RS02725	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B9W05_RS02735	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B9W05_RS02740	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B9W05_RS02745	COG0268	Binds directly to 16S ribosomal RNA
B9W05_RS02750	COG0728	peptidoglycan biosynthetic process
B9W05_RS02755	COG0196	riboflavin kinase activity
B9W05_RS02765	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B9W05_RS02770	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B9W05_RS02785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B9W05_RS02790	COG1845	cytochrome c oxidase, subunit III
B9W05_RS02795	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B9W05_RS02850	COG3209	COG3209 Rhs family protein
B9W05_RS02970	COG0632	four-way junction helicase activity
B9W05_RS02980	COG2255	four-way junction helicase activity
B9W05_RS02985	COG0824	Thioesterase
B9W05_RS02995	COG0848	biopolymer transport protein
B9W05_RS03010	COG2885	chlorophyll binding
B9W05_RS03020	COG0602	queuosine metabolic process
B9W05_RS03030	COG1187	pseudouridine synthase activity
B9W05_RS03090	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B9W05_RS03115	COG0514	ATP-dependent DNA helicase (RecQ)
B9W05_RS03125	COG0783	Belongs to the Dps family
B9W05_RS03130	COG1643	Atp-dependent helicase
B9W05_RS03185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B9W05_RS03195	COG1215	transferase activity, transferring glycosyl groups
B9W05_RS03200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B9W05_RS03210	COG1199	ATP-dependent helicase activity
B9W05_RS03220	COG1397	ADP-ribosylglycohydrolase
B9W05_RS03230	COG0189	ligase activity
B9W05_RS03245	COG0835	chemotaxis
B9W05_RS03250	COG0840	transmembrane signaling receptor activity
B9W05_RS03255	COG0784	Response regulator, receiver
B9W05_RS03255	COG2198	Histidine kinase
B9W05_RS03255	COG0643	Histidine kinase
B9W05_RS03300	COG1446	asparaginase
B9W05_RS03305	COG3142	Participates in the control of copper homeostasis
B9W05_RS03360	COG3537	Alpha-1,2-mannosidase
B9W05_RS03430	COG1472	Belongs to the glycosyl hydrolase 3 family
B9W05_RS03450	COG3858	chitin binding
B9W05_RS03450	COG1388	LysM domain
B9W05_RS03465	COG0837	glucose binding
B9W05_RS03470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B9W05_RS03480	COG0494	nUDIX hydrolase
B9W05_RS03490	COG3956	TIGRFAM MazG family protein
B9W05_RS03505	COG0330	HflC and HflK could
B9W05_RS03520	COG0509	glycine decarboxylation via glycine cleavage system
B9W05_RS03555	COG1960	acyl-CoA dehydrogenase activity
B9W05_RS03565	COG1309	transcriptional regulator
B9W05_RS03570	COG4771	TonB-dependent receptor
B9W05_RS03580	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B9W05_RS03590	COG0463	Glycosyl transferase, family 2
B9W05_RS03610	COG1272	protein, Hemolysin III
B9W05_RS03620	COG0739	heme binding
B9W05_RS03625	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B9W05_RS03630	COG0626	cystathionine gamma-synthase activity
B9W05_RS03640	COG1760	l-serine dehydratase
B9W05_RS03655	COG2353	YceI-like domain
B9W05_RS03665	COG2353	YceI-like domain
B9W05_RS03720	COG3867	Arabinogalactan endo-beta-1,4-galactanase
B9W05_RS03740	COG1960	acyl-CoA dehydrogenase activity
B9W05_RS03745	COG1024	Enoyl-CoA hydratase
B9W05_RS03765	COG1250	3-hydroxyacyl-CoA dehydrogenase
B9W05_RS03765	COG1024	Enoyl-CoA hydratase
B9W05_RS03780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B9W05_RS03810	COG1381	Involved in DNA repair and RecF pathway recombination
B9W05_RS03825	COG2954	triphosphatase activity
B9W05_RS03830	COG2954	triphosphatase activity
B9W05_RS03845	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B9W05_RS03850	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
B9W05_RS03855	COG3046	protein related to deoxyribodipyrimidine photolyase
B9W05_RS03865	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B9W05_RS03870	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
B9W05_RS03875	COG1278	Cold shock
B9W05_RS03895	COG1201	RNA secondary structure unwinding
B9W05_RS03900	COG1793	dna ligase
B9W05_RS03910	COG1793	dna ligase
B9W05_RS03910	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
B9W05_RS03940	COG0183	Belongs to the thiolase family
B9W05_RS03965	COG1451	nucleotide metabolic process
B9W05_RS03980	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B9W05_RS04025	COG1047	Peptidyl-prolyl cis-trans
B9W05_RS04040	COG2824	Alkylphosphonate utilization operon protein PhnA
B9W05_RS04055	COG1902	pentaerythritol trinitrate reductase activity
B9W05_RS04060	COG2814	Major facilitator Superfamily
B9W05_RS04115	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B9W05_RS04115	COG0392	lysyltransferase activity
B9W05_RS04125	COG0251	oxidation-reduction process
B9W05_RS04130	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B9W05_RS04145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B9W05_RS04170	COG1595	DNA-templated transcription, initiation
B9W05_RS04190	COG2878	Part of a membrane complex involved in electron transport
B9W05_RS04200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9W05_RS04200	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9W05_RS04220	COG0833	amino acid
B9W05_RS04225	COG2040	homocysteine
B9W05_RS04240	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B9W05_RS04275	COG0529	Catalyzes the synthesis of activated sulfate
B9W05_RS04275	COG2895	sulfate adenylyltransferase (ATP) activity
B9W05_RS04320	COG1981	membrane
B9W05_RS04340	COG1131	(ABC) transporter
B9W05_RS04345	COG4771	TonB-dependent receptor
B9W05_RS04355	COG0825	malonyl-CoA metabolic process
B9W05_RS04375	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B9W05_RS04380	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B9W05_RS04400	COG0750	zinc metalloprotease
B9W05_RS04410	COG0575	Belongs to the CDS family
B9W05_RS04420	COG0233	cytoplasmic translational termination
B9W05_RS04435	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B9W05_RS04495	COG1393	Belongs to the ArsC family
B9W05_RS04510	COG0367	asparagine synthase
B9W05_RS04525	COG4774	siderophore transport
B9W05_RS04565	COG1566	PFAM secretion protein HlyD family protein
B9W05_RS04570	COG2814	Major facilitator Superfamily
B9W05_RS04615	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B9W05_RS04625	COG1960	acyl-CoA dehydrogenase activity
B9W05_RS04650	COG2914	Belongs to the UPF0125 (RnfH) family
B9W05_RS04660	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B9W05_RS04670	COG0497	DNA recombination
B9W05_RS04680	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B9W05_RS04685	COG0443	Heat shock 70 kDa protein
B9W05_RS04690	COG0484	heat shock protein binding
B9W05_RS04700	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
B9W05_RS04705	COG1605	Chorismate mutase
B9W05_RS04705	COG0287	Prephenate dehydrogenase
B9W05_RS04725	COG0583	DNA-binding transcription factor activity
B9W05_RS04740	COG1132	(ABC) transporter
B9W05_RS04775	COG2850	peptidyl-arginine hydroxylation
B9W05_RS04855	COG1131	(ABC) transporter
B9W05_RS04860	COG1725	Transcriptional regulator
B9W05_RS04870	COG0386	Belongs to the glutathione peroxidase family
B9W05_RS04885	COG2900	Belongs to the SlyX family
B9W05_RS04900	COG1609	Transcriptional regulator
B9W05_RS04910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9W05_RS04920	COG1410	methionine synthase
B9W05_RS04920	COG0646	methionine synthase
B9W05_RS04925	COG1410	methionine synthase
B9W05_RS04925	COG0646	methionine synthase
B9W05_RS04930	COG2226	methyltransferase
B9W05_RS04935	COG1960	acyl-CoA dehydrogenase activity
B9W05_RS04965	COG0557	exoribonuclease II activity
B9W05_RS04985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B9W05_RS05005	COG3039	Transposase
B9W05_RS05030	COG3328	transposase activity
B9W05_RS05040	COG1278	Cold shock
B9W05_RS05055	COG3039	Transposase
B9W05_RS05065	COG3039	Transposase
B9W05_RS05125	COG3039	Transposase
B9W05_RS05175	COG3039	Transposase
B9W05_RS05185	COG0583	DNA-binding transcription factor activity
B9W05_RS05280	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
B9W05_RS05290	COG0531	amino acid
B9W05_RS05295	COG0531	amino acid
B9W05_RS05305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B9W05_RS05310	COG0277	FAD linked oxidase domain protein
B9W05_RS05375	COG0436	Aminotransferase
B9W05_RS05400	COG1187	pseudouridine synthase activity
B9W05_RS05405	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B9W05_RS05410	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B9W05_RS05415	COG2350	Protein conserved in bacteria
B9W05_RS05445	COG1175	transmembrane transport
B9W05_RS05450	COG0395	ABC-type sugar transport system, permease component
B9W05_RS05475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B9W05_RS05485	COG2957	Belongs to the agmatine deiminase family
B9W05_RS05500	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B9W05_RS05505	COG0539	negative regulation of cytoplasmic translation
B9W05_RS05510	COG0776	regulation of translation
B9W05_RS05520	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
B9W05_RS05525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B9W05_RS05535	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B9W05_RS05555	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B9W05_RS05570	COG3002	Belongs to the UPF0753 family
B9W05_RS05575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B9W05_RS05580	COG0583	DNA-binding transcription factor activity
B9W05_RS05610	COG0583	DNA-binding transcription factor activity
B9W05_RS05635	COG1914	H( )-stimulated, divalent metal cation uptake system
B9W05_RS05655	COG0668	transmembrane transport
B9W05_RS05710	COG1028	Short-chain dehydrogenase reductase Sdr
B9W05_RS05715	COG1183	phosphatidylcholine synthase activity
B9W05_RS05725	COG3243	poly(R)-hydroxyalkanoic acid synthase
B9W05_RS05740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9W05_RS05740	COG0723	plastoquinol--plastocyanin reductase activity
B9W05_RS05750	COG2183	response to ionizing radiation
B9W05_RS05765	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
B9W05_RS05780	COG0671	phosphoesterase, PA-phosphatase related
B9W05_RS05805	COG1794	racemase activity, acting on amino acids and derivatives
B9W05_RS05815	COG0697	spore germination
B9W05_RS05840	COG1012	belongs to the aldehyde dehydrogenase family
B9W05_RS05875	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B9W05_RS05890	COG0124	histidyl-tRNA synthetase
B9W05_RS05910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B9W05_RS05925	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B9W05_RS05925	COG0131	Imidazoleglycerol-phosphate dehydratase
B9W05_RS05935	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B9W05_RS05945	COG0140	phosphoribosyl-ATP diphosphatase activity
B9W05_RS05945	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B9W05_RS05985	COG0653	protein targeting
B9W05_RS06135	COG3039	Transposase
B9W05_RS06210	COG2201	protein-glutamate methylesterase activity
B9W05_RS06220	COG2801	Transposase and inactivated derivatives
B9W05_RS06270	COG3328	transposase activity
B9W05_RS06305	COG0322	excinuclease ABC activity
B9W05_RS06315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B9W05_RS06325	COG1663	tetraacyldisaccharide 4'-kinase activity
B9W05_RS06340	COG0811	peptide transport
B9W05_RS06370	COG4591	ABC-type transport system involved in lipoprotein release permease component
B9W05_RS06385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B9W05_RS06400	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B9W05_RS06415	COG0354	folic acid binding
B9W05_RS06430	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B9W05_RS06440	COG0363	glucosamine-6-phosphate deaminase activity
B9W05_RS06445	COG0129	dihydroxy-acid dehydratase activity
B9W05_RS06450	COG0800	Aldolase
B9W05_RS06485	COG2205	protein histidine kinase activity
B9W05_RS06485	COG0784	Response regulator, receiver
B9W05_RS06485	COG5002	protein histidine kinase activity
B9W05_RS06565	COG0386	Belongs to the glutathione peroxidase family
B9W05_RS06655	COG5001	Diguanylate cyclase
B9W05_RS06655	COG2203	Gaf domain
B9W05_RS06655	COG4251	negative regulation of phosphorylation
B9W05_RS06655	COG3706	GGDEF domain
B9W05_RS06675	COG1472	Belongs to the glycosyl hydrolase 3 family
B9W05_RS06725	COG0617	tRNA 3'-terminal CCA addition
B9W05_RS06735	COG1469	GTP cyclohydrolase I activity
B9W05_RS06740	COG0860	N-Acetylmuramoyl-L-alanine amidase
B9W05_RS06790	COG4566	intracellular signal transduction
B9W05_RS06830	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B9W05_RS06835	COG0077	Prephenate dehydratase
B9W05_RS06835	COG1605	Chorismate mutase
B9W05_RS06845	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B9W05_RS06890	COG1228	amidohydrolase
B9W05_RS06895	COG2986	histidine ammonia-lyase
B9W05_RS06905	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B9W05_RS06930	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B9W05_RS06945	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
B9W05_RS06960	COG3115	cell septum assembly
B9W05_RS06970	COG0359	binds to the 23S rRNA
B9W05_RS06980	COG0360	Binds together with S18 to 16S ribosomal RNA
B9W05_RS06985	COG0316	Belongs to the HesB IscA family
B9W05_RS07020	COG0288	reversible hydration of carbon dioxide
B9W05_RS07045	COG2925	Exonuclease
B9W05_RS07055	COG0667	Aldo Keto reductase
B9W05_RS07080	COG0116	Belongs to the methyltransferase superfamily
B9W05_RS07080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B9W05_RS07125	COG0494	nUDIX hydrolase
B9W05_RS07135	COG1024	Enoyl-CoA hydratase
B9W05_RS07145	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B9W05_RS07160	COG3039	Transposase
B9W05_RS07200	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B9W05_RS07205	COG0573	inorganic phosphate transmembrane transporter activity
B9W05_RS07220	COG0704	Plays a role in the regulation of phosphate uptake
B9W05_RS07230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B9W05_RS07245	COG3328	transposase activity
B9W05_RS07280	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B9W05_RS07285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B9W05_RS07290	COG1862	Preprotein translocase
B9W05_RS07295	COG0343	queuine tRNA-ribosyltransferase activity
B9W05_RS07380	COG0405	Gamma-glutamyltransferase
B9W05_RS07385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B9W05_RS07400	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B9W05_RS07405	COG0742	ribosomal rna small subunit methyltransferase
B9W05_RS07425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B9W05_RS07460	COG3039	Transposase
B9W05_RS07490	COG0303	'Molybdopterin
B9W05_RS07500	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B9W05_RS07510	COG1426	Protein conserved in bacteria
B9W05_RS07520	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B9W05_RS07535	COG1024	Enoyl-CoA hydratase
B9W05_RS07535	COG1250	3-hydroxyacyl-CoA dehydrogenase
B9W05_RS07540	COG0183	Belongs to the thiolase family
B9W05_RS07545	COG0038	chloride channel
B9W05_RS07565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B9W05_RS07590	COG1674	ftsk spoiiie
B9W05_RS07595	COG0492	ferredoxin-NADP+ reductase activity
B9W05_RS07620	COG0542	response to heat
B9W05_RS07635	COG0482	sulfurtransferase activity
B9W05_RS07660	COG5001	Diguanylate cyclase
B9W05_RS07665	COG4585	Histidine kinase
B9W05_RS07675	COG5002	protein histidine kinase activity
B9W05_RS07695	COG0784	Response regulator, receiver
B9W05_RS07695	COG0835	chemotaxis
B9W05_RS07705	COG1558	bacterial-type flagellum-dependent cell motility
B9W05_RS07710	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B9W05_RS07720	COG4787	bacterial-type flagellum-dependent cell motility
B9W05_RS07760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B9W05_RS07765	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B9W05_RS07795	COG2201	protein-glutamate methylesterase activity
B9W05_RS07815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B9W05_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
B9W05_RS07860	COG1677	Flagellar hook-basal body complex protein FliE
B9W05_RS07910	COG3190	flagellar
B9W05_RS07930	COG1684	flagellar biosynthetic protein fliR
B9W05_RS07985	COG2198	Histidine kinase
B9W05_RS07985	COG0784	Response regulator, receiver
B9W05_RS07985	COG0643	Histidine kinase
B9W05_RS08025	COG3039	Transposase
B9W05_RS08040	COG3209	COG3209 Rhs family protein
B9W05_RS08050	COG3039	Transposase
B9W05_RS08060	COG3039	Transposase
B9W05_RS08150	COG3039	Transposase
B9W05_RS08165	COG4988	ABC transporter
B9W05_RS08180	COG3039	Transposase
B9W05_RS08215	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B9W05_RS08235	COG0165	Argininosuccinate lyase
B9W05_RS08250	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B9W05_RS08255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9W05_RS08265	COG0137	argininosuccinate synthase activity
B9W05_RS08270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B9W05_RS08285	COG2166	iron-sulfur cluster assembly
B9W05_RS08310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B9W05_RS08350	COG3039	Transposase
B9W05_RS08365	COG4677	pectinesterase activity
B9W05_RS08395	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B9W05_RS08400	COG0402	S-adenosylhomocysteine deaminase activity
B9W05_RS08415	COG1509	lysine 2,3-aminomutase activity
B9W05_RS08420	COG3300	MHYT domain
B9W05_RS08420	COG5001	Diguanylate cyclase
B9W05_RS08435	COG0483	inositol monophosphate 1-phosphatase activity
B9W05_RS08440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B9W05_RS08465	COG0488	(ABC) transporter
B9W05_RS08470	COG0513	Belongs to the DEAD box helicase family
B9W05_RS08490	COG0625	glutathione transferase activity
B9W05_RS08500	COG1671	Belongs to the UPF0178 family
B9W05_RS08505	COG4681	YaeQ
B9W05_RS08510	COG2081	HI0933 family
B9W05_RS08530	COG1028	Short-chain dehydrogenase reductase Sdr
B9W05_RS08555	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B9W05_RS08560	COG0860	N-Acetylmuramoyl-L-alanine amidase
B9W05_RS08565	COG0802	atpase or kinase
B9W05_RS08570	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B9W05_RS08570	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B9W05_RS08575	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B9W05_RS08600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B9W05_RS08685	COG3328	transposase activity
B9W05_RS08730	COG2969	positive regulation of protein catabolic process
B9W05_RS08735	COG0625	glutathione transferase activity
B9W05_RS08740	COG2857	Cytochrome c1
B9W05_RS08750	COG0723	plastoquinol--plastocyanin reductase activity
B9W05_RS08760	COG0741	lytic transglycosylase activity
B9W05_RS08785	COG1702	phosphate starvation-inducible protein PhoH
B9W05_RS08805	COG4535	Mg2 and Co2 transporter CorC
B9W05_RS08820	COG1012	belongs to the aldehyde dehydrogenase family
B9W05_RS08830	COG1177	transmembrane transport
B9W05_RS08835	COG1176	ABC-type spermidine putrescine transport system, permease component I
B9W05_RS08840	COG3842	ATPase activity
B9W05_RS08880	COG0174	glutamine synthetase
B9W05_RS08885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9W05_RS08895	COG0477	Major facilitator Superfamily
B9W05_RS08905	COG0243	molybdopterin cofactor binding
B9W05_RS08915	COG2223	nitrite transmembrane transporter activity
B9W05_RS08925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B9W05_RS08930	COG1121	(ABC) transporter
B9W05_RS08940	COG2733	membrane
B9W05_RS08945	COG0784	Response regulator, receiver
B9W05_RS08945	COG2205	protein histidine kinase activity
B9W05_RS08945	COG5002	protein histidine kinase activity
B9W05_RS08955	COG3039	Transposase
B9W05_RS08975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B9W05_RS08980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B9W05_RS09000	COG1609	Transcriptional regulator
B9W05_RS09005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B9W05_RS09005	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9W05_RS09010	COG1105	Belongs to the carbohydrate kinase PfkB family
B9W05_RS09015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9W05_RS09015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9W05_RS09030	COG3039	Transposase
B9W05_RS09180	COG3039	Transposase
B9W05_RS09210	COG4771	TonB-dependent receptor
B9W05_RS09220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B9W05_RS09240	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B9W05_RS09245	COG1360	Flagellar Motor Protein
B9W05_RS09255	COG0835	chemotaxis
B9W05_RS09265	COG0745	RESPONSE REGULATOR receiver
B9W05_RS09290	COG0840	transmembrane signaling receptor activity
B9W05_RS09305	COG0840	transmembrane signaling receptor activity
B9W05_RS09315	COG0840	transmembrane signaling receptor activity
B9W05_RS09325	COG0840	transmembrane signaling receptor activity
B9W05_RS09330	COG0840	transmembrane signaling receptor activity
B9W05_RS09335	COG0840	transmembrane signaling receptor activity
B9W05_RS09340	COG0840	transmembrane signaling receptor activity
B9W05_RS09360	COG0835	chemotaxis
B9W05_RS09385	COG0840	transmembrane signaling receptor activity
B9W05_RS09420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B9W05_RS09450	COG0318	PFAM AMP-dependent synthetase and ligase
B9W05_RS09455	COG1024	Enoyl-CoA hydratase
B9W05_RS09460	COG2198	Histidine kinase
B9W05_RS09460	COG2205	protein histidine kinase activity
B9W05_RS09460	COG0784	Response regulator, receiver
B9W05_RS09530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B9W05_RS09540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B9W05_RS09545	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B9W05_RS09555	COG0505	Belongs to the CarA family
B9W05_RS09560	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B9W05_RS09570	COG2258	MOSC domain
B9W05_RS09575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B9W05_RS09625	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B9W05_RS09645	COG0477	Major facilitator Superfamily
B9W05_RS09655	COG1070	Carbohydrate kinase
B9W05_RS09665	COG1501	Belongs to the glycosyl hydrolase 31 family
B9W05_RS09680	COG0800	Aldolase
B9W05_RS09685	COG4948	Mandelate Racemase Muconate Lactonizing
B9W05_RS09695	COG3734	2-keto-3-deoxy-galactonokinase
B9W05_RS09700	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B9W05_RS09710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B9W05_RS09725	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B9W05_RS09730	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B9W05_RS09740	COG0351	phosphomethylpyrimidine kinase
B9W05_RS09770	COG0583	DNA-binding transcription factor activity
B9W05_RS09775	COG1741	Belongs to the pirin family
B9W05_RS09795	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B9W05_RS09800	COG0305	Participates in initiation and elongation during chromosome replication
B9W05_RS09825	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
B9W05_RS09830	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B9W05_RS09835	COG2137	regulation of response to DNA damage stimulus
B9W05_RS09845	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B9W05_RS09860	COG1546	Belongs to the CinA family
B9W05_RS09865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B9W05_RS09880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B9W05_RS09890	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
B9W05_RS09895	COG1534	Rna-binding protein
B9W05_RS09910	COG1238	metal cluster binding
B9W05_RS09915	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B9W05_RS09920	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B9W05_RS09925	COG2840	Smr protein MutS2
B9W05_RS09935	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B9W05_RS09950	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B9W05_RS09955	COG0148	phosphopyruvate hydratase activity
B9W05_RS09965	COG2877	3-deoxy-8-phosphooctulonate synthase activity
B9W05_RS09970	COG0504	CTP synthase activity
B9W05_RS09995	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B9W05_RS10000	COG0306	phosphate transporter
B9W05_RS10015	COG1253	flavin adenine dinucleotide binding
B9W05_RS10030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9W05_RS10050	COG0477	Major facilitator Superfamily
B9W05_RS10060	COG1132	(ABC) transporter
B9W05_RS10065	COG1136	(ABC) transporter
B9W05_RS10085	COG0438	transferase activity, transferring glycosyl groups
B9W05_RS10095	COG2264	protein methyltransferase activity
B9W05_RS10125	COG2244	polysaccharide biosynthetic process
B9W05_RS10175	COG1595	DNA-templated transcription, initiation
B9W05_RS10190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B9W05_RS10210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9W05_RS10265	COG2201	protein-glutamate methylesterase activity
B9W05_RS10285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B9W05_RS10290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B9W05_RS10345	COG1858	cytochrome C peroxidase
B9W05_RS10380	COG0515	serine threonine protein kinase
B9W05_RS10385	COG0631	protein serine/threonine phosphatase activity
B9W05_RS10500	COG3039	Transposase
B9W05_RS10520	COG3039	Transposase
B9W05_RS10565	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B9W05_RS10565	COG0316	Belongs to the HesB IscA family
B9W05_RS10570	COG2154	pterin-4-alpha-carbinolamine dehydratase
B9W05_RS10580	COG0428	transporter
B9W05_RS10585	COG0428	transporter
B9W05_RS10600	COG1530	ribonuclease E activity
B9W05_RS10620	COG1054	Belongs to the UPF0176 family
B9W05_RS10625	COG3039	Transposase
B9W05_RS10645	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B9W05_RS10685	COG3039	Transposase
B9W05_RS10690	COG3039	Transposase
B9W05_RS10720	COG1648	precorrin-2 dehydrogenase activity
B9W05_RS10720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B9W05_RS10745	COG0746	molybdenum cofactor guanylyltransferase activity
B9W05_RS10825	COG4206	TonB-dependent receptor
B9W05_RS10855	COG4206	TonB-dependent receptor
B9W05_RS10905	COG0531	amino acid
B9W05_RS10920	COG0006	proline dipeptidase activity
B9W05_RS10930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B9W05_RS10945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9W05_RS10950	COG3938	Belongs to the proline racemase family
B9W05_RS10960	COG0552	protein localization to endoplasmic reticulum
B9W05_RS10985	COG4191	Histidine kinase
B9W05_RS10985	COG0784	Response regulator, receiver
B9W05_RS11075	COG3040	lipid binding
B9W05_RS11115	COG0438	transferase activity, transferring glycosyl groups
B9W05_RS11125	COG0438	transferase activity, transferring glycosyl groups
B9W05_RS11130	COG0438	transferase activity, transferring glycosyl groups
B9W05_RS11200	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B9W05_RS11240	COG4969	Belongs to the N-Me-Phe pilin family
B9W05_RS11280	COG1611	Belongs to the LOG family
B9W05_RS11295	COG2095	MarC family integral membrane protein
B9W05_RS11305	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B9W05_RS11340	COG1185	polyribonucleotide nucleotidyltransferase activity
B9W05_RS11345	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B9W05_RS11365	COG0195	Participates in both transcription termination and antitermination
B9W05_RS11370	COG0779	Required for maturation of 30S ribosomal subunits
B9W05_RS11380	COG1007	ATP synthesis coupled electron transport
B9W05_RS11410	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B9W05_RS11415	COG1034	ATP synthesis coupled electron transport
B9W05_RS11420	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B9W05_RS11425	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
B9W05_RS11430	COG0649	NAD binding
B9W05_RS11435	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9W05_RS11445	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9W05_RS11460	COG0149	triose-phosphate isomerase activity
B9W05_RS11510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B9W05_RS11515	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B9W05_RS11540	COG0135	phosphoribosylanthranilate isomerase activity
B9W05_RS11545	COG0101	tRNA pseudouridine synthase activity
B9W05_RS11565	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B9W05_RS11570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B9W05_RS11575	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B9W05_RS11580	COG2890	protein-(glutamine-N5) methyltransferase activity
B9W05_RS11635	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B9W05_RS11645	COG0412	Dienelactone hydrolase
B9W05_RS11670	COG0717	Belongs to the dCTP deaminase family
B9W05_RS11675	COG0489	protein tyrosine kinase activity
B9W05_RS11720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9W05_RS11725	COG2311	Membrane
B9W05_RS11730	COG1047	Peptidyl-prolyl cis-trans
B9W05_RS11735	COG0791	NLP P60 protein
B9W05_RS11740	COG0791	NLP P60 protein
B9W05_RS11755	COG1301	dicarboxylic acid transport
B9W05_RS11760	COG1785	Belongs to the alkaline phosphatase family
B9W05_RS11765	COG0037	tRNA processing
B9W05_RS11770	COG1722	exodeoxyribonuclease VII activity
B9W05_RS11775	COG0142	geranyltranstransferase activity
B9W05_RS11800	COG0312	modulator of DNA gyrase
B9W05_RS11805	COG3028	Belongs to the UPF0307 family
B9W05_RS11810	COG0312	modulator of DNA gyrase
B9W05_RS11820	COG3164	Protein of unknown function
B9W05_RS11835	COG2968	Membrane
B9W05_RS11860	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B9W05_RS11885	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B9W05_RS11915	COG3118	belongs to the thioredoxin family
B9W05_RS12005	COG3039	Transposase
B9W05_RS12010	COG3039	Transposase
B9W05_RS12105	COG2022	thiamine diphosphate biosynthetic process
B9W05_RS12120	COG3273	potassium ion transport
B9W05_RS12120	COG0471	metal ion transport
B9W05_RS12150	COG1970	mechanosensitive ion channel activity
B9W05_RS12175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B9W05_RS12205	COG0308	aminopeptidase N
B9W05_RS12210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B9W05_RS12225	COG2895	sulfate adenylyltransferase (ATP) activity
B9W05_RS12225	COG0529	Catalyzes the synthesis of activated sulfate
B9W05_RS12230	COG0175	sulfate reduction
B9W05_RS12235	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B9W05_RS12240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B9W05_RS12245	COG0175	sulfate reduction
B9W05_RS12265	COG2205	protein histidine kinase activity
B9W05_RS12265	COG2198	Histidine kinase
B9W05_RS12265	COG0784	Response regulator, receiver
B9W05_RS12310	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B9W05_RS12315	COG3588	fructose-bisphosphate aldolase
B9W05_RS12320	COG0469	pyruvate kinase activity
B9W05_RS12365	COG0753	catalase activity
B9W05_RS12390	COG3039	Transposase
B9W05_RS12410	COG1917	Cupin 2, conserved barrel domain protein
B9W05_RS12410	COG2207	Transcriptional regulator
B9W05_RS12440	COG0823	Involved in the tonB-independent uptake of proteins
B9W05_RS12440	COG1506	peptidase
B9W05_RS12465	COG3039	Transposase
B9W05_RS12470	COG1297	OPT oligopeptide transporter protein
B9W05_RS12575	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
B9W05_RS12590	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
B9W05_RS12595	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
B9W05_RS12600	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
B9W05_RS12620	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
B9W05_RS12775	COG3179	chitinase
B9W05_RS12885	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B9W05_RS12940	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B9W05_RS12950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B9W05_RS13040	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B9W05_RS13055	COG2197	response regulator
B9W05_RS13060	COG4585	Histidine kinase
B9W05_RS13080	COG2894	cell division
B9W05_RS13085	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
B9W05_RS13095	COG0642	Histidine kinase
B9W05_RS13100	COG0745	RESPONSE REGULATOR receiver
B9W05_RS13105	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B9W05_RS13115	COG2194	sulfuric ester hydrolase activity
B9W05_RS13145	COG3551	Protein conserved in bacteria
B9W05_RS13210	COG0203	ribosomal protein L17
B9W05_RS13220	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B9W05_RS13225	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B9W05_RS13235	COG0201	protein transport
B9W05_RS13245	COG1841	ribosomal large subunit assembly
B9W05_RS13275	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B9W05_RS13285	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B9W05_RS13290	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B9W05_RS13295	COG0255	Belongs to the universal ribosomal protein uL29 family
B9W05_RS13300	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B9W05_RS13310	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B9W05_RS13325	COG0089	rRNA binding
B9W05_RS13330	COG0088	Forms part of the polypeptide exit tunnel
B9W05_RS13335	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B9W05_RS13340	COG0051	transcription antitermination factor activity, RNA binding
B9W05_RS13360	COG0049	tRNA binding
B9W05_RS13365	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B9W05_RS13370	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B9W05_RS13375	COG0085	RNA polymerase activity
B9W05_RS13380	COG0222	ribosome binding
B9W05_RS13385	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B9W05_RS13395	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B9W05_RS13405	COG0250	Participates in transcription elongation, termination and antitermination
B9W05_RS13410	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B9W05_RS13440	COG0012	GTP binding
B9W05_RS13445	COG0193	aminoacyl-tRNA hydrolase activity
B9W05_RS13455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B9W05_RS13470	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
B9W05_RS13485	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B9W05_RS13495	COG0521	Mo-molybdopterin cofactor biosynthetic process
B9W05_RS13515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9W05_RS13520	COG1295	ribonuclease BN
B9W05_RS13550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B9W05_RS13560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B9W05_RS13590	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
B9W05_RS13615	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
B9W05_RS13630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B9W05_RS13630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B9W05_RS13680	COG2890	protein-(glutamine-N5) methyltransferase activity
B9W05_RS13690	COG3634	alkyl hydroperoxide reductase activity
B9W05_RS13695	COG0583	DNA-binding transcription factor activity
B9W05_RS13705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B9W05_RS13785	COG4783	chaperone-mediated protein folding
B9W05_RS13800	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
B9W05_RS13810	COG0438	transferase activity, transferring glycosyl groups
B9W05_RS13815	COG0671	phosphoesterase, PA-phosphatase related
B9W05_RS13820	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B9W05_RS13840	COG2833	Protein of unknown function (DUF455)
B9W05_RS13860	COG0285	dihydrofolate synthase activity
B9W05_RS13870	COG0406	alpha-ribazole phosphatase activity
B9W05_RS13905	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B9W05_RS13910	COG4208	sulfate ABC transporter
B9W05_RS13915	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B9W05_RS13920	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
B9W05_RS13925	COG0156	8-amino-7-oxononanoate synthase activity
B9W05_RS13955	COG0604	alcohol dehydrogenase
B9W05_RS13960	COG1902	pentaerythritol trinitrate reductase activity
B9W05_RS13960	COG0446	pyridine nucleotide-disulphide oxidoreductase
B9W05_RS14100	COG3386	PFAM SMP-30 Gluconolaconase
B9W05_RS14120	COG1024	Enoyl-CoA hydratase
B9W05_RS14130	COG0318	PFAM AMP-dependent synthetase and ligase
B9W05_RS14135	COG0583	DNA-binding transcription factor activity
B9W05_RS14175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B9W05_RS14180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B9W05_RS14190	COG2096	Adenosyltransferase
B9W05_RS14195	COG0123	including yeast histone deacetylase and acetoin utilization protein
B9W05_RS14210	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B9W05_RS14220	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B9W05_RS14225	COG2967	ApaG domain
B9W05_RS14250	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B9W05_RS14270	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B9W05_RS14285	COG0642	Histidine kinase
B9W05_RS14300	COG4181	ATPase activity
B9W05_RS14310	COG2175	clavaminate synthase activity
B9W05_RS14320	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B9W05_RS14360	COG0667	Aldo Keto reductase
B9W05_RS14370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B9W05_RS14375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9W05_RS14395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B9W05_RS14410	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B9W05_RS14465	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B9W05_RS14470	COG2226	methyltransferase
B9W05_RS14525	COG0604	alcohol dehydrogenase
B9W05_RS14525	COG3321	synthase
B9W05_RS14525	COG1028	Short-chain dehydrogenase reductase Sdr
B9W05_RS14540	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B9W05_RS14555	COG0494	nUDIX hydrolase
B9W05_RS14570	COG4942	peptidase
B9W05_RS14570	COG1388	LysM domain
B9W05_RS14580	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
B9W05_RS14595	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B9W05_RS14600	COG1181	Belongs to the D-alanine--D-alanine ligase family
B9W05_RS14605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B9W05_RS14620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B9W05_RS14625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B9W05_RS14640	COG3116	cell division
B9W05_RS14645	COG0275	rRNA processing
B9W05_RS14680	COG0792	nuclease activity
B9W05_RS14685	COG1988	membrane-bound metal-dependent
B9W05_RS14690	COG0277	FAD linked oxidase domain protein
B9W05_RS14695	COG0745	RESPONSE REGULATOR receiver
B9W05_RS14700	COG2205	protein histidine kinase activity
B9W05_RS14710	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B9W05_RS14715	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B9W05_RS14740	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B9W05_RS14745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B9W05_RS14750	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B9W05_RS14770	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B9W05_RS14770	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B9W05_RS14790	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B9W05_RS14810	COG0488	(ABC) transporter
B9W05_RS14860	COG2205	protein histidine kinase activity
B9W05_RS14900	COG2205	protein histidine kinase activity
B9W05_RS14920	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B9W05_RS14955	COG3039	Transposase
B9W05_RS14960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B9W05_RS14975	COG3039	Transposase
B9W05_RS15030	COG3039	Transposase
B9W05_RS15080	COG1649	PFAM Uncharacterised BCR, COG1649
B9W05_RS15080	COG0726	polysaccharide deacetylase
B9W05_RS15085	COG1215	transferase activity, transferring glycosyl groups
B9W05_RS15095	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B9W05_RS15100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B9W05_RS15105	COG1609	Transcriptional regulator
B9W05_RS15115	COG2188	Transcriptional regulator
B9W05_RS15130	COG3250	beta-galactosidase activity
B9W05_RS15185	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B9W05_RS15190	COG4191	Histidine kinase
B9W05_RS15195	COG0784	Response regulator, receiver
B9W05_RS15200	COG4251	negative regulation of phosphorylation
B9W05_RS15205	COG2823	Periplasmic or secreted lipoprotein
B9W05_RS15210	COG0673	inositol 2-dehydrogenase activity
B9W05_RS15215	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B9W05_RS15250	COG1056	cytidyltransferase-related domain
B9W05_RS15250	COG1051	belongs to the nudix hydrolase family
B9W05_RS15285	COG2921	Belongs to the UPF0250 family
B9W05_RS15300	COG1686	Belongs to the peptidase S11 family
B9W05_RS15310	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B9W05_RS15315	COG2951	lytic endotransglycosylase activity
B9W05_RS15330	COG5632	N-Acetylmuramoyl-L-alanine amidase
B9W05_RS15330	COG3409	Peptidoglycan-binding domain 1 protein
B9W05_RS15330	COG1388	LysM domain
B9W05_RS15375	COG0772	Belongs to the SEDS family
B9W05_RS15395	COG1077	Cell shape determining protein MreB Mrl
B9W05_RS15400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9W05_RS15405	COG3039	Transposase
B9W05_RS15455	COG2199	diguanylate cyclase activity
B9W05_RS15460	COG0308	aminopeptidase N
B9W05_RS15490	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B9W05_RS15520	COG0436	Aminotransferase
B9W05_RS15535	COG1505	serine-type exopeptidase activity
B9W05_RS15560	COG0181	hydroxymethylbilane synthase activity
B9W05_RS15570	COG3275	phosphorelay sensor kinase activity
B9W05_RS15615	COG0659	secondary active sulfate transmembrane transporter activity
B9W05_RS15620	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B9W05_RS15620	COG5297	Belongs to the glycosyl hydrolase family 6
B9W05_RS15695	COG0598	Magnesium transport protein CorA
B9W05_RS15705	COG1113	amino acid transport
B9W05_RS15715	COG5297	Belongs to the glycosyl hydrolase family 6
B9W05_RS15720	COG4305	rare lipoprotein A
B9W05_RS15725	COG0697	spore germination
B9W05_RS15785	COG4221	oxidoreductase activity
B9W05_RS15815	COG0456	acetyltransferase
B9W05_RS15825	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B9W05_RS15860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B9W05_RS15860	COG2111	Na H antiporter
B9W05_RS15865	COG1006	Multisubunit Na H antiporter MnhC subunit
B9W05_RS15870	COG0651	ATP synthesis coupled electron transport
B9W05_RS15880	COG2212	antiporter activity
B9W05_RS15885	COG1320	monovalent cation:proton antiporter activity
B9W05_RS15900	COG3039	Transposase
B9W05_RS15905	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
B9W05_RS15925	COG3104	oligopeptide transport
B9W05_RS15930	COG3483	tryptophan 2,3-dioxygenase activity
B9W05_RS15940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B9W05_RS15975	COG0183	Belongs to the thiolase family
B9W05_RS16030	COG3039	Transposase
B9W05_RS16060	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
B9W05_RS16065	COG3023	N-Acetylmuramoyl-L-alanine amidase
B9W05_RS16075	COG4948	Mandelate Racemase Muconate Lactonizing
B9W05_RS16115	COG0531	amino acid
B9W05_RS16150	COG4682	membrane
B9W05_RS16155	COG3039	Transposase
B9W05_RS16160	COG2133	pyrroloquinoline quinone binding
B9W05_RS16200	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B9W05_RS16205	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B9W05_RS16215	COG1610	YqeY-like protein
B9W05_RS16230	COG1295	ribonuclease BN
B9W05_RS16235	COG0358	DNA primase activity
B9W05_RS16300	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
B9W05_RS16315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B9W05_RS16365	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B9W05_RS16370	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B9W05_RS16375	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
B9W05_RS16385	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B9W05_RS16390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B9W05_RS16405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B9W05_RS16485	COG3039	Transposase
B9W05_RS16500	COG3328	transposase activity
B9W05_RS16515	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B9W05_RS16515	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B9W05_RS16525	COG1473	amidohydrolase
B9W05_RS16530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B9W05_RS16535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B9W05_RS16550	COG5383	Protein conserved in bacteria
B9W05_RS16590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B9W05_RS16595	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
B9W05_RS16610	COG0028	Belongs to the TPP enzyme family
B9W05_RS16615	COG4191	Histidine kinase
B9W05_RS16640	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B9W05_RS16655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B9W05_RS16660	COG3177	Filamentation induced by cAMP protein fic
B9W05_RS16675	COG0596	Alpha beta hydrolase
B9W05_RS16680	COG0727	PFAM Uncharacterised protein family (UPF0153)
B9W05_RS16685	COG0318	PFAM AMP-dependent synthetase and ligase
B9W05_RS16690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9W05_RS16745	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B9W05_RS16755	COG0129	dihydroxy-acid dehydratase activity
B9W05_RS16795	COG0408	coproporphyrinogen oxidase activity
B9W05_RS16845	COG3039	Transposase
B9W05_RS16905	COG2353	YceI-like domain
B9W05_RS16935	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B9W05_RS16950	COG3386	PFAM SMP-30 Gluconolaconase
B9W05_RS16990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B9W05_RS17005	COG4771	TonB-dependent receptor
B9W05_RS17015	COG0459	protein refolding
B9W05_RS17040	COG1252	NADH dehydrogenase
B9W05_RS17050	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B9W05_RS17055	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B9W05_RS17060	COG3437	response regulator, receiver
B9W05_RS17065	COG2177	Part of the ABC transporter FtsEX involved in
B9W05_RS17070	COG2884	Cell division ATP-binding protein ftsE
B9W05_RS17080	COG3118	belongs to the thioredoxin family
B9W05_RS17085	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B9W05_RS17100	COG0729	surface antigen
B9W05_RS17105	COG2911	Protein conserved in bacteria
B9W05_RS17140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B9W05_RS17155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B9W05_RS17210	COG1733	regulation of RNA biosynthetic process
B9W05_RS17215	COG0702	epimerase
B9W05_RS17245	COG0583	DNA-binding transcription factor activity
B9W05_RS17250	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B9W05_RS17270	COG0745	RESPONSE REGULATOR receiver
B9W05_RS17300	COG1902	pentaerythritol trinitrate reductase activity
B9W05_RS17305	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B9W05_RS17315	COG2814	Major facilitator Superfamily
B9W05_RS17320	COG0583	DNA-binding transcription factor activity
B9W05_RS17340	COG0084	hydrolase, TatD family'
B9W05_RS17390	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B9W05_RS17460	COG4770	biotin carboxylase activity
B9W05_RS17465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B9W05_RS17470	COG1960	acyl-CoA dehydrogenase activity
B9W05_RS17525	COG0523	cobalamin synthesis protein
B9W05_RS17540	COG0697	spore germination
B9W05_RS17550	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B9W05_RS17565	COG4771	TonB-dependent receptor
B9W05_RS17570	COG0457	Tetratricopeptide repeat
B9W05_RS17585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B9W05_RS17615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B9W05_RS17615	COG0519	Catalyzes the synthesis of GMP from XMP
B9W05_RS17625	COG0805	protein transport
B9W05_RS17635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B9W05_RS17645	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B9W05_RS17700	COG3661	Belongs to the glycosyl hydrolase 67 family
B9W05_RS17710	COG4948	Mandelate Racemase Muconate Lactonizing
B9W05_RS17720	COG1472	Belongs to the glycosyl hydrolase 3 family
B9W05_RS17725	COG0246	Mannitol dehydrogenase
B9W05_RS17750	COG3693	PFAM glycoside hydrolase, family 10
B9W05_RS17775	COG2211	Major facilitator Superfamily
B9W05_RS17820	COG4943	cyclic-guanylate-specific phosphodiesterase activity
B9W05_RS17870	COG1846	Transcriptional regulator
B9W05_RS17875	COG1764	response to oxidative stress
B9W05_RS17975	COG3549	Plasmid maintenance system killer
B9W05_RS17985	COG1074	ATP-dependent DNA helicase activity
B9W05_RS17990	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
B9W05_RS17995	COG1196	nuclear chromosome segregation
B9W05_RS18035	COG2032	superoxide dismutase activity
B9W05_RS18040	COG2032	superoxide dismutase activity
B9W05_RS18045	COG2204	response regulator
B9W05_RS18050	COG3852	Histidine kinase
B9W05_RS18055	COG0004	ammonium transporteR
B9W05_RS18060	COG0347	Belongs to the P(II) protein family
B9W05_RS18065	COG0174	glutamine synthetase
B9W05_RS18070	COG1968	undecaprenyl-diphosphatase activity
B9W05_RS18115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B9W05_RS18125	COG2062	phosphohistidine phosphatase, SixA
B9W05_RS18130	COG0489	protein tyrosine kinase activity
B9W05_RS18150	COG1396	sequence-specific DNA binding
B9W05_RS18155	COG3550	peptidyl-serine autophosphorylation
B9W05_RS18160	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
B9W05_RS18165	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B9W05_RS18180	COG0517	IMP dehydrogenase activity
B9W05_RS18180	COG1125	glycine betaine transport
B9W05_RS18195	COG1119	ATPase activity
B9W05_RS18205	COG1752	Esterase of the alpha-beta hydrolase superfamily
B9W05_RS18220	COG3039	Transposase
B9W05_RS18245	COG0656	L-ascorbic acid biosynthetic process
B9W05_RS18250	COG2130	NADP-dependent
B9W05_RS18255	COG0667	Aldo Keto reductase
B9W05_RS18265	COG1187	pseudouridine synthase activity
B9W05_RS18280	COG1643	Atp-dependent helicase
B9W05_RS18285	COG4807	Protein conserved in bacteria
B9W05_RS18290	COG4948	Mandelate Racemase Muconate Lactonizing
B9W05_RS18300	COG0179	Fumarylacetoacetate (FAA) hydrolase
B9W05_RS18305	COG1028	Short-chain dehydrogenase reductase Sdr
B9W05_RS18325	COG3507	Belongs to the glycosyl hydrolase 43 family
B9W05_RS18370	COG3162	membrane
B9W05_RS18375	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B9W05_RS18390	COG0708	Exodeoxyribonuclease III
B9W05_RS18405	COG2091	lysine biosynthetic process via aminoadipic acid
B9W05_RS18415	COG3540	Alkaline phosphatase
B9W05_RS18445	COG2159	amidohydrolase
B9W05_RS18470	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B9W05_RS18475	COG0583	DNA-binding transcription factor activity
B9W05_RS18480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B9W05_RS18500	COG0210	DNA helicase
B9W05_RS18515	COG0531	amino acid
B9W05_RS18525	COG1322	Protein conserved in bacteria
B9W05_RS18535	COG0386	Belongs to the glutathione peroxidase family
B9W05_RS18590	COG0793	Belongs to the peptidase S41A family
B9W05_RS18595	COG4942	peptidase
B9W05_RS18605	COG2234	aminopeptidase activity
B9W05_RS18655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B9W05_RS18660	COG0302	gtp cyclohydrolase
B9W05_RS18685	COG0477	Major facilitator Superfamily
B9W05_RS18785	COG1929	Belongs to the glycerate kinase type-1 family
B9W05_RS18790	COG2271	Major facilitator Superfamily
B9W05_RS18805	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B9W05_RS18815	COG0861	Integral membrane protein TerC family
B9W05_RS18825	COG0584	glycerophosphoryl diester phosphodiesterase
B9W05_RS18835	COG0671	phosphoesterase, PA-phosphatase related
B9W05_RS18845	COG0726	polysaccharide deacetylase
B9W05_RS18870	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B9W05_RS18890	COG0187	DNA topoisomerase II activity
B9W05_RS18900	COG0501	Belongs to the peptidase M48B family
B9W05_RS18940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B9W05_RS18950	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
B9W05_RS18960	COG4772	TonB-dependent receptor
B9W05_RS18975	COG3039	Transposase
B9W05_RS18980	COG1304	FMN binding
B9W05_RS18985	COG1755	Isoprenylcysteine carboxyl methyltransferase
B9W05_RS19010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9W05_RS19020	COG3039	Transposase
B9W05_RS19030	COG1136	(ABC) transporter
B9W05_RS19080	COG3039	Transposase
B9W05_RS19090	COG0513	Belongs to the DEAD box helicase family
B9W05_RS19190	COG1858	cytochrome C peroxidase
B9W05_RS19200	COG0702	epimerase
B9W05_RS19225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B9W05_RS19245	COG1649	PFAM Uncharacterised BCR, COG1649
B9W05_RS19250	COG2354	Protein conserved in bacteria
B9W05_RS19260	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B9W05_RS19275	COG3264	Mechanosensitive ion channel
B9W05_RS19275	COG1511	domain protein
B9W05_RS19315	COG3039	Transposase
B9W05_RS19365	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B9W05_RS19445	COG3039	Transposase
B9W05_RS19460	COG3039	Transposase
B9W05_RS19500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B9W05_RS19510	COG0642	Histidine kinase
B9W05_RS19520	COG1090	epimerase
B9W05_RS19530	COG3039	Transposase
B9W05_RS19555	COG2826	transposase and inactivated derivatives, IS30 family
B9W05_RS19615	COG1136	(ABC) transporter
B9W05_RS19660	COG1272	protein, Hemolysin III
B9W05_RS19665	COG1111	helicase
B9W05_RS19665	COG1205	dead DEAH box helicase
B9W05_RS19725	COG0069	glutamate synthase activity
B9W05_RS19725	COG0067	glutamate synthase
B9W05_RS19725	COG0070	glutamate synthase
B9W05_RS19730	COG0493	'glutamate synthase
B9W05_RS19780	COG1609	Transcriptional regulator
B9W05_RS19815	COG0366	Alpha amylase catalytic
B9W05_RS19820	COG0366	Alpha amylase catalytic
B9W05_RS19870	COG0606	chelatase, subunit chli
B9W05_RS19915	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B9W05_RS19920	COG1166	arginine decarboxylase activity
B9W05_RS19985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B9W05_RS20010	COG1028	Short-chain dehydrogenase reductase Sdr
B9W05_RS20035	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
B9W05_RS20050	COG0210	DNA helicase
B9W05_RS20065	COG3132	Protein of unknown function, DUF480
B9W05_RS20070	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
B9W05_RS20075	COG0284	orotidine-5'-phosphate decarboxylase activity
B9W05_RS20110	COG2937	Belongs to the GPAT DAPAT family
B9W05_RS20140	COG2755	lipolytic protein G-D-S-L family
B9W05_RS20155	COG3186	Phenylalanine-4-hydroxylase
B9W05_RS20160	COG1522	sequence-specific DNA binding
B9W05_RS20205	COG1064	alcohol dehydrogenase
B9W05_RS20215	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B9W05_RS20225	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B9W05_RS20235	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B9W05_RS20260	COG3039	Transposase
B9W05_RS20265	COG0676	glucose-6-phosphate 1-epimerase activity
B9W05_RS20330	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B9W05_RS20355	COG2853	Lipoprotein
B9W05_RS20370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B9W05_RS20375	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B9W05_RS20380	COG1127	ABC transporter
B9W05_RS20455	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B9W05_RS20470	COG3265	gluconokinase activity
B9W05_RS20475	COG2211	Major facilitator Superfamily
B9W05_RS20480	COG3459	Glycosyltransferase 36 associated
B9W05_RS20495	COG2205	protein histidine kinase activity
B9W05_RS20505	COG1414	Transcriptional regulator
B9W05_RS20510	COG0738	Major facilitator superfamily
B9W05_RS20515	COG3254	rhamnose metabolic process
B9W05_RS20545	COG0339	signal peptide processing
B9W05_RS20575	COG0564	pseudouridine synthase activity
B9W05_RS20585	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B9W05_RS20685	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B9W05_RS20695	COG0842	Transport permease protein
B9W05_RS20700	COG1131	(ABC) transporter
B9W05_RS20705	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B9W05_RS20725	COG1476	TRANSCRIPTIONal
B9W05_RS20735	COG4555	ABC transporter
B9W05_RS20770	COG0625	glutathione transferase activity
B9W05_RS20830	COG0583	DNA-binding transcription factor activity
B9W05_RS20865	COG1199	ATP-dependent helicase activity
B9W05_RS20890	COG1566	PFAM secretion protein HlyD family protein
B9W05_RS20920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B9W05_RS20960	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
B9W05_RS20960	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
B9W05_RS20965	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B9W05_RS20980	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B9W05_RS21015	COG3237	CsbD-like
B9W05_RS21020	COG0180	Tryptophanyl-tRNA synthetase
B9W05_RS21025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9W05_RS21075	COG0753	catalase activity
B9W05_RS21080	COG1595	DNA-templated transcription, initiation
B9W05_RS21090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B9W05_RS21100	COG0628	permease
B9W05_RS21115	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B9W05_RS21120	COG1040	competence protein
B9W05_RS21125	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B9W05_RS21130	COG0156	8-amino-7-oxononanoate synthase activity
B9W05_RS21145	COG1028	Short-chain dehydrogenase reductase Sdr
B9W05_RS21160	COG0463	Glycosyl transferase, family 2
B9W05_RS21170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B9W05_RS21175	COG3100	YcgL domain-containing protein
B9W05_RS21190	COG3387	PFAM Glycoside hydrolase 15-related
B9W05_RS21195	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B9W05_RS21215	COG2239	Acts as a magnesium transporter
B9W05_RS21225	COG0045	succinate-CoA ligase (ADP-forming) activity
B9W05_RS21225	COG1042	CoA-binding domain protein
B9W05_RS21225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B9W05_RS21235	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9W05_RS21245	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9W05_RS21280	COG3485	protocatechuate 3,4-dioxygenase
B9W05_RS21285	COG3485	protocatechuate 3,4-dioxygenase
B9W05_RS21295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B9W05_RS21300	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B9W05_RS21305	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B9W05_RS21330	COG4221	oxidoreductase activity
B9W05_RS21355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B9W05_RS21380	COG0463	Glycosyl transferase, family 2
B9W05_RS21395	COG1475	DNA binding
B9W05_RS21400	COG1192	Involved in chromosome partitioning
B9W05_RS21415	COG0708	Exodeoxyribonuclease III
B9W05_RS21420	COG2211	Major facilitator Superfamily
B9W05_RS21435	COG0739	heme binding
B9W05_RS21480	COG0745	RESPONSE REGULATOR receiver
B9W05_RS21525	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
B9W05_RS21550	COG2814	Major facilitator Superfamily
B9W05_RS21565	COG1289	transmembrane transporter activity
B9W05_RS21575	COG1136	(ABC) transporter
B9W05_RS21575	COG0577	efflux transmembrane transporter activity
B9W05_RS21580	COG0151	Belongs to the GarS family
B9W05_RS21590	COG0419	ATPase involved in DNA repair
B9W05_RS21605	COG2267	carboxylic ester hydrolase activity
B9W05_RS21615	COG2267	carboxylic ester hydrolase activity
B9W05_RS21620	COG0671	phosphoesterase, PA-phosphatase related
B9W05_RS21620	COG2453	phosphatase
B9W05_RS21635	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
B9W05_RS21695	COG0439	Biotin carboxylase
B9W05_RS21705	COG0511	ligase activity, forming carbon-carbon bonds
B9W05_RS21710	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B9W05_RS21730	COG1324	tolerance protein
B9W05_RS21765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B9W05_RS21795	COG0534	Mate efflux family protein
B9W05_RS21800	COG0616	signal peptide processing
B9W05_RS21810	COG1028	Short-chain dehydrogenase reductase Sdr
B9W05_RS21825	COG0009	L-threonylcarbamoyladenylate synthase
B9W05_RS21830	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B9W05_RS21830	COG1754	DNA topoisomerase type I activity
B9W05_RS21845	COG2922	Belongs to the Smg family
B9W05_RS21850	COG0758	DNA mediated transformation
B9W05_RS21855	COG1652	LysM domain
B9W05_RS21860	COG0242	peptide deformylase activity
B9W05_RS21865	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B9W05_RS21870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B9W05_RS21870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B9W05_RS21920	COG1560	Kdo2-lipid A biosynthetic process
B9W05_RS21930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B9W05_RS22165	COG1294	oxidase, subunit
B9W05_RS22170	COG1271	oxidase subunit
B9W05_RS22185	COG2204	response regulator
B9W05_RS22215	COG2972	Histidine kinase
B9W05_RS22230	COG0531	amino acid
B9W05_RS22250	COG3590	peptidase
B9W05_RS22265	COG0667	Aldo Keto reductase
B9W05_RS22280	COG3384	dioxygenase
B9W05_RS22290	COG1573	uracil-dna glycosylase
B9W05_RS22300	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
B9W05_RS22315	COG0025	NhaP-type Na H and K H
B9W05_RS22320	COG1131	(ABC) transporter
B9W05_RS22325	COG0842	Transport permease protein
B9W05_RS22340	COG1404	Belongs to the peptidase S8 family
B9W05_RS22355	COG0745	RESPONSE REGULATOR receiver
B9W05_RS22405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9W05_RS22430	COG2205	protein histidine kinase activity
B9W05_RS22430	COG2202	Pas domain
B9W05_RS22465	COG2813	Specifically methylates the guanine in position
B9W05_RS22470	COG1187	pseudouridine synthase activity
B9W05_RS22475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B9W05_RS22510	COG0697	spore germination
B9W05_RS22520	COG2011	ABC-type metal ion transport system permease component
B9W05_RS22550	COG0508	dehydrogenase complex catalyzes the overall conversion of
B9W05_RS22560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B9W05_RS22580	COG0356	it plays a direct role in the translocation of protons across the membrane
B9W05_RS22590	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B9W05_RS22600	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B9W05_RS22605	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B9W05_RS22610	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B9W05_RS22615	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B9W05_RS22670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B9W05_RS22675	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B9W05_RS22730	COG0339	signal peptide processing
B9W05_RS22770	COG1956	GAF domain-containing protein
B9W05_RS22775	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B9W05_RS22785	COG0720	synthase
B9W05_RS22795	COG0513	Belongs to the DEAD box helicase family
B9W05_RS22840	COG0626	cystathionine gamma-synthase activity
B9W05_RS22890	COG3328	transposase activity
B9W05_RS22915	COG2086	electron transfer activity
B9W05_RS22940	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
B9W05_RS22940	COG0662	Cupin 2, conserved barrel domain protein
B9W05_RS22945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B9W05_RS22960	COG3039	Transposase
B9W05_RS22990	COG3218	ABC-type transport auxiliary lipoprotein component
B9W05_RS22990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B9W05_RS22995	COG1127	ABC transporter
B9W05_RS23000	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B9W05_RS23015	COG0442	prolyl-tRNA aminoacylation
B9W05_RS23025	COG1183	phosphatidylcholine synthase activity
B9W05_RS23055	COG3039	Transposase
B9W05_RS23125	COG0525	valine-tRNA ligase activity
B9W05_RS23140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B9W05_RS23150	COG0795	lipopolysaccharide-transporting ATPase activity
B9W05_RS23165	COG4974	Belongs to the 'phage' integrase family
B9W05_RS23170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B9W05_RS23175	COG0047	phosphoribosylformylglycinamidine synthase activity
B9W05_RS23175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B9W05_RS23185	COG5295	Hep Hag repeat protein
B9W05_RS23205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B9W05_RS23215	COG1459	type II secretion system
B9W05_RS23220	COG2165	general secretion pathway protein
B9W05_RS23225	COG4970	Tfp pilus assembly protein FimT
B9W05_RS23230	COG2165	general secretion pathway protein
B9W05_RS23235	COG4795	General secretion pathway protein
B9W05_RS23240	COG3156	type II secretion system protein K
B9W05_RS23245	COG3166	PFAM Fimbrial assembly family protein
B9W05_RS23260	COG1450	Type ii and iii secretion system protein
B9W05_RS23275	COG2188	Transcriptional regulator
B9W05_RS23335	COG3039	Transposase
B9W05_RS23340	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
B9W05_RS23345	COG1518	maintenance of DNA repeat elements
B9W05_RS23390	COG1399	metal-binding, possibly nucleic acid-binding protein
B9W05_RS23415	COG1028	Short-chain dehydrogenase reductase Sdr
B9W05_RS23420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B9W05_RS23430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B9W05_RS23435	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B9W05_RS23460	COG3829	transcription factor binding
B9W05_RS23540	COG2826	transposase and inactivated derivatives, IS30 family
B9W05_RS23550	COG0678	peroxiredoxin activity
B9W05_RS23570	COG0330	HflC and HflK could
B9W05_RS23575	COG0330	HflC and HflK could
B9W05_RS23590	COG0308	aminopeptidase N
B9W05_RS23640	COG1560	Kdo2-lipid A biosynthetic process
B9W05_RS23645	COG1519	Transferase
B9W05_RS23650	COG1538	Outer membrane efflux protein
B9W05_RS23655	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B9W05_RS23680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B9W05_RS23685	COG0066	3-isopropylmalate dehydratase activity
B9W05_RS23720	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B9W05_RS23730	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B9W05_RS23735	COG3710	Transcriptional regulator
B9W05_RS23760	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B9W05_RS23780	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
B9W05_RS23810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B9W05_RS23820	COG3781	membrane
B9W05_RS23840	COG0625	glutathione transferase activity
B9W05_RS23850	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B9W05_RS23855	COG1217	gtp-binding protein TYPA
B9W05_RS23875	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
B9W05_RS23940	COG3039	Transposase
B9W05_RS24020	COG3039	Transposase
B9W05_RS24045	COG0584	glycerophosphoryl diester phosphodiesterase
B9W05_RS24070	COG0473	3-isopropylmalate dehydrogenase activity
B9W05_RS24125	COG0544	peptidyl-prolyl cis-trans isomerase activity
B9W05_RS24165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B9W05_RS24190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B9W05_RS24200	COG0631	protein serine/threonine phosphatase activity
B9W05_RS24285	COG0582	viral genome integration into host DNA
B9W05_RS24295	COG0859	PFAM glycosyl transferase family 9
B9W05_RS24300	COG3642	lipopolysaccharide core region biosynthetic process
B9W05_RS24305	COG1234	tRNA 3'-trailer cleavage
B9W05_RS24310	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B9W05_RS24320	COG0315	cyclic pyranopterin monophosphate synthase activity
B9W05_RS24325	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
B9W05_RS24330	COG0314	molybdopterin synthase activity
B9W05_RS24360	COG0537	adenosine 5'-monophosphoramidase activity
B9W05_RS24380	COG0714	Associated with various cellular activities
B9W05_RS24400	COG0242	peptide deformylase activity
B9W05_RS24450	COG3039	Transposase
B9W05_RS24480	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B9W05_RS24485	COG0726	polysaccharide deacetylase
B9W05_RS24535	COG2211	Major facilitator Superfamily
B9W05_RS24545	COG1609	Transcriptional regulator
B9W05_RS24550	COG1028	Short-chain dehydrogenase reductase Sdr
B9W05_RS24555	COG2851	Citrate transporter
B9W05_RS24575	COG0642	Histidine kinase
B9W05_RS24585	COG2197	response regulator
B9W05_RS24605	COG0583	DNA-binding transcription factor activity
B9W05_RS24620	COG4191	Histidine kinase
B9W05_RS24640	COG0280	phosphate acetyltransferase
B9W05_RS24640	COG0281	malic enzyme
B9W05_RS24675	COG0352	thiamine-phosphate diphosphorylase activity
B9W05_RS24680	COG1773	rubredoxin
B9W05_RS24685	COG2912	Transglutaminase-like superfamily