locus-tag	class	description
CDO19_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDO19_RS00030	COG0187	DNA topoisomerase II activity
CDO19_RS00040	COG0501	Belongs to the peptidase M48B family
CDO19_RS00080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDO19_RS00090	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CDO19_RS00100	COG4772	TonB-dependent receptor
CDO19_RS00115	COG3039	Transposase
CDO19_RS00120	COG1304	FMN binding
CDO19_RS00125	COG1755	Isoprenylcysteine carboxyl methyltransferase
CDO19_RS00150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO19_RS00160	COG3039	Transposase
CDO19_RS00170	COG1136	(ABC) transporter
CDO19_RS00220	COG3039	Transposase
CDO19_RS00230	COG0513	Belongs to the DEAD box helicase family
CDO19_RS00335	COG1858	cytochrome C peroxidase
CDO19_RS00350	COG0702	epimerase
CDO19_RS00375	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CDO19_RS00395	COG1649	PFAM Uncharacterised BCR, COG1649
CDO19_RS00400	COG2354	Protein conserved in bacteria
CDO19_RS00410	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDO19_RS00425	COG3264	Mechanosensitive ion channel
CDO19_RS00425	COG1511	domain protein
CDO19_RS00465	COG3039	Transposase
CDO19_RS00515	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDO19_RS00595	COG3039	Transposase
CDO19_RS00610	COG3039	Transposase
CDO19_RS00650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO19_RS00660	COG0642	Histidine kinase
CDO19_RS00670	COG1090	epimerase
CDO19_RS00680	COG3039	Transposase
CDO19_RS00705	COG2826	transposase and inactivated derivatives, IS30 family
CDO19_RS00770	COG1136	(ABC) transporter
CDO19_RS00815	COG1272	protein, Hemolysin III
CDO19_RS00820	COG1111	helicase
CDO19_RS00820	COG1205	dead DEAH box helicase
CDO19_RS00885	COG0070	glutamate synthase
CDO19_RS00885	COG0069	glutamate synthase activity
CDO19_RS00885	COG0067	glutamate synthase
CDO19_RS00890	COG0493	'glutamate synthase
CDO19_RS00940	COG1609	Transcriptional regulator
CDO19_RS00975	COG0366	Alpha amylase catalytic
CDO19_RS00980	COG0366	Alpha amylase catalytic
CDO19_RS01035	COG0606	chelatase, subunit chli
CDO19_RS01080	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CDO19_RS01085	COG1166	arginine decarboxylase activity
CDO19_RS01150	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDO19_RS01175	COG1028	Short-chain dehydrogenase reductase Sdr
CDO19_RS01200	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CDO19_RS01215	COG0210	DNA helicase
CDO19_RS01230	COG3132	Protein of unknown function, DUF480
CDO19_RS01235	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CDO19_RS01240	COG0284	orotidine-5'-phosphate decarboxylase activity
CDO19_RS01275	COG2937	Belongs to the GPAT DAPAT family
CDO19_RS01305	COG2755	lipolytic protein G-D-S-L family
CDO19_RS01320	COG3186	Phenylalanine-4-hydroxylase
CDO19_RS01325	COG1522	sequence-specific DNA binding
CDO19_RS01375	COG1064	alcohol dehydrogenase
CDO19_RS01385	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CDO19_RS01395	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CDO19_RS01405	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CDO19_RS01430	COG3039	Transposase
CDO19_RS01435	COG0676	glucose-6-phosphate 1-epimerase activity
CDO19_RS01500	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CDO19_RS01525	COG2853	Lipoprotein
CDO19_RS01540	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CDO19_RS01545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDO19_RS01550	COG1127	ABC transporter
CDO19_RS01625	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDO19_RS01640	COG3265	gluconokinase activity
CDO19_RS01645	COG2211	Major facilitator Superfamily
CDO19_RS01650	COG3459	Glycosyltransferase 36 associated
CDO19_RS01660	COG2205	protein histidine kinase activity
CDO19_RS01670	COG1414	Transcriptional regulator
CDO19_RS01675	COG0738	Major facilitator superfamily
CDO19_RS01680	COG3254	rhamnose metabolic process
CDO19_RS01710	COG0339	signal peptide processing
CDO19_RS01740	COG0564	pseudouridine synthase activity
CDO19_RS01750	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDO19_RS01850	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CDO19_RS01860	COG0842	Transport permease protein
CDO19_RS01865	COG1131	(ABC) transporter
CDO19_RS01870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDO19_RS01890	COG1476	TRANSCRIPTIONal
CDO19_RS01900	COG4555	ABC transporter
CDO19_RS01935	COG0625	glutathione transferase activity
CDO19_RS01995	COG0583	DNA-binding transcription factor activity
CDO19_RS02030	COG1199	ATP-dependent helicase activity
CDO19_RS02055	COG1566	PFAM secretion protein HlyD family protein
CDO19_RS02085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDO19_RS02125	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CDO19_RS02125	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CDO19_RS02130	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CDO19_RS02145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CDO19_RS02185	COG3237	CsbD-like
CDO19_RS02190	COG0180	Tryptophanyl-tRNA synthetase
CDO19_RS02195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO19_RS02245	COG0753	catalase activity
CDO19_RS02250	COG1595	DNA-templated transcription, initiation
CDO19_RS02260	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CDO19_RS02270	COG0628	permease
CDO19_RS02285	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDO19_RS02290	COG1040	competence protein
CDO19_RS02295	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDO19_RS02300	COG0156	8-amino-7-oxononanoate synthase activity
CDO19_RS02315	COG1028	Short-chain dehydrogenase reductase Sdr
CDO19_RS02330	COG0463	Glycosyl transferase, family 2
CDO19_RS02340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDO19_RS02345	COG3100	YcgL domain-containing protein
CDO19_RS02365	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CDO19_RS02385	COG2239	Acts as a magnesium transporter
CDO19_RS02395	COG0045	succinate-CoA ligase (ADP-forming) activity
CDO19_RS02395	COG1042	CoA-binding domain protein
CDO19_RS02395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO19_RS02405	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDO19_RS02415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDO19_RS02450	COG3485	protocatechuate 3,4-dioxygenase
CDO19_RS02455	COG3485	protocatechuate 3,4-dioxygenase
CDO19_RS02465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CDO19_RS02470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDO19_RS02475	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDO19_RS02500	COG4221	oxidoreductase activity
CDO19_RS02525	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDO19_RS02550	COG0463	Glycosyl transferase, family 2
CDO19_RS02565	COG1475	DNA binding
CDO19_RS02570	COG1192	Involved in chromosome partitioning
CDO19_RS02585	COG0708	Exodeoxyribonuclease III
CDO19_RS02590	COG2211	Major facilitator Superfamily
CDO19_RS02610	COG0739	heme binding
CDO19_RS02655	COG0745	RESPONSE REGULATOR receiver
CDO19_RS02700	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CDO19_RS02725	COG2814	Major facilitator Superfamily
CDO19_RS02740	COG1289	transmembrane transporter activity
CDO19_RS02750	COG0577	efflux transmembrane transporter activity
CDO19_RS02750	COG1136	(ABC) transporter
CDO19_RS02755	COG0151	Belongs to the GarS family
CDO19_RS02765	COG0419	ATPase involved in DNA repair
CDO19_RS02780	COG2267	carboxylic ester hydrolase activity
CDO19_RS02785	COG2267	carboxylic ester hydrolase activity
CDO19_RS02790	COG2267	carboxylic ester hydrolase activity
CDO19_RS02810	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CDO19_RS02870	COG0439	Biotin carboxylase
CDO19_RS02880	COG0511	ligase activity, forming carbon-carbon bonds
CDO19_RS02885	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CDO19_RS02905	COG1324	tolerance protein
CDO19_RS02940	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDO19_RS02965	COG0534	Mate efflux family protein
CDO19_RS02970	COG0616	signal peptide processing
CDO19_RS02980	COG1028	Short-chain dehydrogenase reductase Sdr
CDO19_RS02995	COG0009	L-threonylcarbamoyladenylate synthase
CDO19_RS03000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDO19_RS03000	COG1754	DNA topoisomerase type I activity
CDO19_RS03015	COG2922	Belongs to the Smg family
CDO19_RS03020	COG0758	DNA mediated transformation
CDO19_RS03025	COG1652	LysM domain
CDO19_RS03030	COG0242	peptide deformylase activity
CDO19_RS03035	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDO19_RS03040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDO19_RS03040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDO19_RS03090	COG1560	Kdo2-lipid A biosynthetic process
CDO19_RS03100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDO19_RS03350	COG1294	oxidase, subunit
CDO19_RS03355	COG1271	oxidase subunit
CDO19_RS03370	COG2204	response regulator
CDO19_RS03400	COG2972	Histidine kinase
CDO19_RS03415	COG0531	amino acid
CDO19_RS03435	COG3590	peptidase
CDO19_RS03450	COG0667	Aldo Keto reductase
CDO19_RS03465	COG3384	dioxygenase
CDO19_RS03475	COG1573	uracil-dna glycosylase
CDO19_RS03485	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CDO19_RS03495	COG0025	NhaP-type Na H and K H
CDO19_RS03500	COG1131	(ABC) transporter
CDO19_RS03505	COG0842	Transport permease protein
CDO19_RS03520	COG1404	Belongs to the peptidase S8 family
CDO19_RS03535	COG0745	RESPONSE REGULATOR receiver
CDO19_RS03585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO19_RS03610	COG2205	protein histidine kinase activity
CDO19_RS03610	COG2202	Pas domain
CDO19_RS03640	COG2813	Specifically methylates the guanine in position
CDO19_RS03645	COG1187	pseudouridine synthase activity
CDO19_RS03650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDO19_RS03685	COG0697	spore germination
CDO19_RS03695	COG2011	ABC-type metal ion transport system permease component
CDO19_RS03725	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO19_RS03735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDO19_RS03755	COG0356	it plays a direct role in the translocation of protons across the membrane
CDO19_RS03765	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDO19_RS03775	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDO19_RS03780	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDO19_RS03785	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDO19_RS03790	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CDO19_RS03840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO19_RS03845	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDO19_RS03900	COG0339	signal peptide processing
CDO19_RS03940	COG1956	GAF domain-containing protein
CDO19_RS03945	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CDO19_RS03955	COG0720	synthase
CDO19_RS03965	COG0513	Belongs to the DEAD box helicase family
CDO19_RS04010	COG0626	cystathionine gamma-synthase activity
CDO19_RS04060	COG3328	transposase activity
CDO19_RS04085	COG2086	electron transfer activity
CDO19_RS04110	COG0662	Cupin 2, conserved barrel domain protein
CDO19_RS04110	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CDO19_RS04115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDO19_RS04130	COG3039	Transposase
CDO19_RS04160	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CDO19_RS04160	COG3218	ABC-type transport auxiliary lipoprotein component
CDO19_RS04165	COG1127	ABC transporter
CDO19_RS04170	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDO19_RS04185	COG0442	prolyl-tRNA aminoacylation
CDO19_RS04195	COG1183	phosphatidylcholine synthase activity
CDO19_RS04225	COG3039	Transposase
CDO19_RS04295	COG0525	valine-tRNA ligase activity
CDO19_RS04310	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CDO19_RS04320	COG0795	lipopolysaccharide-transporting ATPase activity
CDO19_RS04335	COG4974	Belongs to the 'phage' integrase family
CDO19_RS04340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDO19_RS04345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDO19_RS04345	COG0047	phosphoribosylformylglycinamidine synthase activity
CDO19_RS04355	COG5295	Hep Hag repeat protein
CDO19_RS04375	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDO19_RS04385	COG1459	type II secretion system
CDO19_RS04390	COG2165	general secretion pathway protein
CDO19_RS04395	COG4970	Tfp pilus assembly protein FimT
CDO19_RS04400	COG2165	general secretion pathway protein
CDO19_RS04405	COG4795	General secretion pathway protein
CDO19_RS04410	COG3156	type II secretion system protein K
CDO19_RS04415	COG3166	PFAM Fimbrial assembly family protein
CDO19_RS04430	COG1450	Type ii and iii secretion system protein
CDO19_RS04445	COG2188	Transcriptional regulator
CDO19_RS04505	COG3039	Transposase
CDO19_RS04510	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CDO19_RS04515	COG1518	maintenance of DNA repeat elements
CDO19_RS04560	COG1399	metal-binding, possibly nucleic acid-binding protein
CDO19_RS04585	COG1028	Short-chain dehydrogenase reductase Sdr
CDO19_RS04590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO19_RS04600	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDO19_RS04605	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDO19_RS04640	COG3829	transcription factor binding
CDO19_RS04730	COG2826	transposase and inactivated derivatives, IS30 family
CDO19_RS04740	COG0678	peroxiredoxin activity
CDO19_RS04760	COG0330	HflC and HflK could
CDO19_RS04765	COG0330	HflC and HflK could
CDO19_RS04780	COG0308	aminopeptidase N
CDO19_RS04830	COG1560	Kdo2-lipid A biosynthetic process
CDO19_RS04835	COG1519	Transferase
CDO19_RS04840	COG1538	Outer membrane efflux protein
CDO19_RS04845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO19_RS04870	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDO19_RS04875	COG0066	3-isopropylmalate dehydratase activity
CDO19_RS04910	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDO19_RS04920	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDO19_RS04925	COG3710	Transcriptional regulator
CDO19_RS04950	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CDO19_RS04970	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CDO19_RS05000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDO19_RS05010	COG3781	membrane
CDO19_RS05030	COG0625	glutathione transferase activity
CDO19_RS05040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDO19_RS05045	COG1217	gtp-binding protein TYPA
CDO19_RS05065	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CDO19_RS05135	COG3039	Transposase
CDO19_RS05215	COG3039	Transposase
CDO19_RS05240	COG0584	glycerophosphoryl diester phosphodiesterase
CDO19_RS05265	COG0473	3-isopropylmalate dehydrogenase activity
CDO19_RS05320	COG0544	peptidyl-prolyl cis-trans isomerase activity
CDO19_RS05360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDO19_RS05385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDO19_RS05395	COG0631	protein serine/threonine phosphatase activity
CDO19_RS05480	COG0582	viral genome integration into host DNA
CDO19_RS05490	COG0859	PFAM glycosyl transferase family 9
CDO19_RS05495	COG3642	lipopolysaccharide core region biosynthetic process
CDO19_RS05500	COG1234	tRNA 3'-trailer cleavage
CDO19_RS05505	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDO19_RS05515	COG0315	cyclic pyranopterin monophosphate synthase activity
CDO19_RS05520	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CDO19_RS05525	COG0314	molybdopterin synthase activity
CDO19_RS05555	COG0537	adenosine 5'-monophosphoramidase activity
CDO19_RS05575	COG0714	Associated with various cellular activities
CDO19_RS05595	COG0242	peptide deformylase activity
CDO19_RS05645	COG3039	Transposase
CDO19_RS05675	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CDO19_RS05680	COG0726	polysaccharide deacetylase
CDO19_RS05730	COG2211	Major facilitator Superfamily
CDO19_RS05740	COG1609	Transcriptional regulator
CDO19_RS05745	COG1028	Short-chain dehydrogenase reductase Sdr
CDO19_RS05750	COG2851	Citrate transporter
CDO19_RS05770	COG0642	Histidine kinase
CDO19_RS05780	COG2197	response regulator
CDO19_RS05800	COG0583	DNA-binding transcription factor activity
CDO19_RS05815	COG4191	Histidine kinase
CDO19_RS05835	COG0281	malic enzyme
CDO19_RS05835	COG0280	phosphate acetyltransferase
CDO19_RS05870	COG0352	thiamine-phosphate diphosphorylase activity
CDO19_RS05875	COG1773	rubredoxin
CDO19_RS05880	COG2912	Transglutaminase-like superfamily
CDO19_RS05900	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDO19_RS05925	COG0006	proline dipeptidase activity
CDO19_RS05960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDO19_RS05975	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDO19_RS05980	COG1561	YicC-like family, N-terminal region
CDO19_RS06005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDO19_RS06015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDO19_RS06040	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDO19_RS06090	COG0714	Associated with various cellular activities
CDO19_RS06110	COG2304	oxidoreductase activity
CDO19_RS06130	COG1301	dicarboxylic acid transport
CDO19_RS06135	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDO19_RS06140	COG4773	Receptor
CDO19_RS06145	COG0739	heme binding
CDO19_RS06150	COG1376	ErfK ybiS ycfS ynhG family protein
CDO19_RS06175	COG1022	Amp-dependent synthetase and ligase
CDO19_RS06185	COG1028	Short-chain dehydrogenase reductase Sdr
CDO19_RS06200	COG0642	Histidine kinase
CDO19_RS06220	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CDO19_RS06225	COG4149	molybdate abc transporter
CDO19_RS06230	COG0725	ABC transporter, periplasmic molybdate-binding protein
CDO19_RS06235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO19_RS06235	COG3453	Protein conserved in bacteria
CDO19_RS06265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDO19_RS06285	COG2205	protein histidine kinase activity
CDO19_RS06290	COG0745	RESPONSE REGULATOR receiver
CDO19_RS06305	COG3039	Transposase
CDO19_RS06340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDO19_RS06345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDO19_RS06390	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CDO19_RS06480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO19_RS06500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDO19_RS06515	COG1595	DNA-templated transcription, initiation
CDO19_RS06565	COG2244	polysaccharide biosynthetic process
CDO19_RS06595	COG2264	protein methyltransferase activity
CDO19_RS06605	COG0438	transferase activity, transferring glycosyl groups
CDO19_RS06625	COG1136	(ABC) transporter
CDO19_RS06630	COG1132	(ABC) transporter
CDO19_RS06640	COG0477	Major facilitator Superfamily
CDO19_RS06660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO19_RS06675	COG1253	flavin adenine dinucleotide binding
CDO19_RS06690	COG0306	phosphate transporter
CDO19_RS06695	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CDO19_RS06720	COG0504	CTP synthase activity
CDO19_RS06725	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CDO19_RS06735	COG0148	phosphopyruvate hydratase activity
CDO19_RS06740	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CDO19_RS06755	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CDO19_RS06770	COG2840	Smr protein MutS2
CDO19_RS06775	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CDO19_RS06780	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO19_RS06785	COG1238	metal cluster binding
CDO19_RS06800	COG1534	Rna-binding protein
CDO19_RS06805	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CDO19_RS06815	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDO19_RS06830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDO19_RS06835	COG1546	Belongs to the CinA family
CDO19_RS06850	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDO19_RS06855	COG2137	regulation of response to DNA damage stimulus
CDO19_RS06860	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDO19_RS06865	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CDO19_RS06890	COG0305	Participates in initiation and elongation during chromosome replication
CDO19_RS06895	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDO19_RS06915	COG1741	Belongs to the pirin family
CDO19_RS06920	COG0583	DNA-binding transcription factor activity
CDO19_RS06950	COG0351	phosphomethylpyrimidine kinase
CDO19_RS06960	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CDO19_RS06965	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDO19_RS06980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO19_RS06990	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CDO19_RS06995	COG3734	2-keto-3-deoxy-galactonokinase
CDO19_RS07005	COG4948	Mandelate Racemase Muconate Lactonizing
CDO19_RS07010	COG0800	Aldolase
CDO19_RS07025	COG1501	Belongs to the glycosyl hydrolase 31 family
CDO19_RS07035	COG1070	Carbohydrate kinase
CDO19_RS07045	COG0477	Major facilitator Superfamily
CDO19_RS07065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDO19_RS07115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO19_RS07120	COG2258	MOSC domain
CDO19_RS07130	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDO19_RS07135	COG0505	Belongs to the CarA family
CDO19_RS07145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDO19_RS07150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO19_RS07160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDO19_RS07230	COG2198	Histidine kinase
CDO19_RS07230	COG0784	Response regulator, receiver
CDO19_RS07230	COG2205	protein histidine kinase activity
CDO19_RS07235	COG1024	Enoyl-CoA hydratase
CDO19_RS07240	COG0318	PFAM AMP-dependent synthetase and ligase
CDO19_RS07270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDO19_RS07305	COG0840	transmembrane signaling receptor activity
CDO19_RS07330	COG0835	chemotaxis
CDO19_RS07350	COG0840	transmembrane signaling receptor activity
CDO19_RS07355	COG0840	transmembrane signaling receptor activity
CDO19_RS07360	COG0840	transmembrane signaling receptor activity
CDO19_RS07365	COG0840	transmembrane signaling receptor activity
CDO19_RS07375	COG0840	transmembrane signaling receptor activity
CDO19_RS07385	COG0840	transmembrane signaling receptor activity
CDO19_RS07400	COG0840	transmembrane signaling receptor activity
CDO19_RS07430	COG0745	RESPONSE REGULATOR receiver
CDO19_RS07440	COG0835	chemotaxis
CDO19_RS07450	COG1360	Flagellar Motor Protein
CDO19_RS07455	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CDO19_RS07475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDO19_RS07485	COG4771	TonB-dependent receptor
CDO19_RS07515	COG3039	Transposase
CDO19_RS07665	COG3039	Transposase
CDO19_RS07680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDO19_RS07680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDO19_RS07685	COG1105	Belongs to the carbohydrate kinase PfkB family
CDO19_RS07690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDO19_RS07690	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO19_RS07695	COG1609	Transcriptional regulator
CDO19_RS07715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO19_RS07720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO19_RS07740	COG3039	Transposase
CDO19_RS07750	COG5002	protein histidine kinase activity
CDO19_RS07750	COG2205	protein histidine kinase activity
CDO19_RS07750	COG0784	Response regulator, receiver
CDO19_RS07755	COG2733	membrane
CDO19_RS07765	COG1121	(ABC) transporter
CDO19_RS07770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO19_RS07780	COG2223	nitrite transmembrane transporter activity
CDO19_RS07790	COG0243	molybdopterin cofactor binding
CDO19_RS07800	COG0477	Major facilitator Superfamily
CDO19_RS07810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO19_RS07815	COG0174	glutamine synthetase
CDO19_RS07855	COG3842	ATPase activity
CDO19_RS07865	COG1177	transmembrane transport
CDO19_RS07875	COG1012	belongs to the aldehyde dehydrogenase family
CDO19_RS07890	COG4535	Mg2 and Co2 transporter CorC
CDO19_RS07910	COG1702	phosphate starvation-inducible protein PhoH
CDO19_RS07935	COG0741	lytic transglycosylase activity
CDO19_RS07945	COG0723	plastoquinol--plastocyanin reductase activity
CDO19_RS07950	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CDO19_RS07955	COG2857	Cytochrome c1
CDO19_RS07960	COG0625	glutathione transferase activity
CDO19_RS07965	COG2969	positive regulation of protein catabolic process
CDO19_RS08010	COG3328	transposase activity
CDO19_RS08095	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDO19_RS08120	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDO19_RS08125	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDO19_RS08125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDO19_RS08130	COG0802	atpase or kinase
CDO19_RS08135	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDO19_RS08140	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDO19_RS08165	COG1028	Short-chain dehydrogenase reductase Sdr
CDO19_RS08185	COG2081	HI0933 family
CDO19_RS08190	COG4681	YaeQ
CDO19_RS08195	COG1671	Belongs to the UPF0178 family
CDO19_RS08205	COG0625	glutathione transferase activity
CDO19_RS08225	COG0513	Belongs to the DEAD box helicase family
CDO19_RS08230	COG0488	(ABC) transporter
CDO19_RS08255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDO19_RS08260	COG0483	inositol monophosphate 1-phosphatase activity
CDO19_RS08275	COG3300	MHYT domain
CDO19_RS08275	COG5001	Diguanylate cyclase
CDO19_RS08280	COG1509	lysine 2,3-aminomutase activity
CDO19_RS08295	COG0402	S-adenosylhomocysteine deaminase activity
CDO19_RS08300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDO19_RS08325	COG4677	pectinesterase activity
CDO19_RS08340	COG3039	Transposase
CDO19_RS08380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDO19_RS08405	COG2166	iron-sulfur cluster assembly
CDO19_RS08420	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDO19_RS08425	COG0137	argininosuccinate synthase activity
CDO19_RS08435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDO19_RS08440	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDO19_RS08455	COG0165	Argininosuccinate lyase
CDO19_RS08475	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CDO19_RS08510	COG3039	Transposase
CDO19_RS08525	COG4988	ABC transporter
CDO19_RS08540	COG3039	Transposase
CDO19_RS08625	COG3039	Transposase
CDO19_RS08635	COG3039	Transposase
CDO19_RS08645	COG3209	COG3209 Rhs family protein
CDO19_RS08660	COG3039	Transposase
CDO19_RS08705	COG2198	Histidine kinase
CDO19_RS08705	COG0784	Response regulator, receiver
CDO19_RS08705	COG0643	Histidine kinase
CDO19_RS08760	COG1684	flagellar biosynthetic protein fliR
CDO19_RS08780	COG3190	flagellar
CDO19_RS08830	COG1677	Flagellar hook-basal body complex protein FliE
CDO19_RS08865	COG1028	Short-chain dehydrogenase reductase Sdr
CDO19_RS08875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDO19_RS08895	COG2201	protein-glutamate methylesterase activity
CDO19_RS08925	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CDO19_RS08930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDO19_RS08970	COG4787	bacterial-type flagellum-dependent cell motility
CDO19_RS08980	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CDO19_RS08985	COG1558	bacterial-type flagellum-dependent cell motility
CDO19_RS08995	COG0835	chemotaxis
CDO19_RS08995	COG0784	Response regulator, receiver
CDO19_RS09015	COG5002	protein histidine kinase activity
CDO19_RS09025	COG4585	Histidine kinase
CDO19_RS09030	COG5001	Diguanylate cyclase
CDO19_RS09055	COG0482	sulfurtransferase activity
CDO19_RS09070	COG0542	response to heat
CDO19_RS09095	COG0492	ferredoxin-NADP+ reductase activity
CDO19_RS09100	COG1674	ftsk spoiiie
CDO19_RS09125	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDO19_RS09145	COG0038	chloride channel
CDO19_RS09150	COG0183	Belongs to the thiolase family
CDO19_RS09155	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO19_RS09155	COG1024	Enoyl-CoA hydratase
CDO19_RS09170	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDO19_RS09180	COG1426	Protein conserved in bacteria
CDO19_RS09190	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDO19_RS09200	COG0303	'Molybdopterin
CDO19_RS09230	COG3039	Transposase
CDO19_RS09265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CDO19_RS09285	COG0742	ribosomal rna small subunit methyltransferase
CDO19_RS09290	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CDO19_RS09305	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDO19_RS09310	COG0405	Gamma-glutamyltransferase
CDO19_RS09395	COG0343	queuine tRNA-ribosyltransferase activity
CDO19_RS09400	COG1862	Preprotein translocase
CDO19_RS09405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CDO19_RS09410	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CDO19_RS09445	COG3328	transposase activity
CDO19_RS09460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDO19_RS09470	COG0704	Plays a role in the regulation of phosphate uptake
CDO19_RS09485	COG0573	inorganic phosphate transmembrane transporter activity
CDO19_RS09490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDO19_RS09530	COG3039	Transposase
CDO19_RS09545	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDO19_RS09555	COG1024	Enoyl-CoA hydratase
CDO19_RS09565	COG0494	nUDIX hydrolase
CDO19_RS09610	COG0116	Belongs to the methyltransferase superfamily
CDO19_RS09610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CDO19_RS09635	COG0667	Aldo Keto reductase
CDO19_RS09645	COG2925	Exonuclease
CDO19_RS09670	COG0288	reversible hydration of carbon dioxide
CDO19_RS09705	COG0316	Belongs to the HesB IscA family
CDO19_RS09710	COG0360	Binds together with S18 to 16S ribosomal RNA
CDO19_RS09720	COG0359	binds to the 23S rRNA
CDO19_RS09730	COG3115	cell septum assembly
CDO19_RS09745	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CDO19_RS09760	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CDO19_RS09785	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CDO19_RS09795	COG2986	histidine ammonia-lyase
CDO19_RS09800	COG1228	amidohydrolase
CDO19_RS09845	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CDO19_RS09855	COG1605	Chorismate mutase
CDO19_RS09855	COG0077	Prephenate dehydratase
CDO19_RS09860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDO19_RS09900	COG4566	intracellular signal transduction
CDO19_RS09955	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDO19_RS09960	COG1469	GTP cyclohydrolase I activity
CDO19_RS09970	COG0617	tRNA 3'-terminal CCA addition
CDO19_RS10020	COG1472	Belongs to the glycosyl hydrolase 3 family
CDO19_RS10040	COG3706	GGDEF domain
CDO19_RS10040	COG5001	Diguanylate cyclase
CDO19_RS10040	COG4251	negative regulation of phosphorylation
CDO19_RS10040	COG2203	Gaf domain
CDO19_RS10130	COG0386	Belongs to the glutathione peroxidase family
CDO19_RS10210	COG5002	protein histidine kinase activity
CDO19_RS10210	COG2205	protein histidine kinase activity
CDO19_RS10210	COG0784	Response regulator, receiver
CDO19_RS10245	COG0800	Aldolase
CDO19_RS10250	COG0129	dihydroxy-acid dehydratase activity
CDO19_RS10255	COG0363	glucosamine-6-phosphate deaminase activity
CDO19_RS10265	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CDO19_RS10280	COG0354	folic acid binding
CDO19_RS10295	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CDO19_RS10310	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CDO19_RS10325	COG4591	ABC-type transport system involved in lipoprotein release permease component
CDO19_RS10355	COG0811	peptide transport
CDO19_RS10370	COG1663	tetraacyldisaccharide 4'-kinase activity
CDO19_RS10380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDO19_RS10390	COG0322	excinuclease ABC activity
CDO19_RS10425	COG3328	transposase activity
CDO19_RS10480	COG2801	Transposase and inactivated derivatives
CDO19_RS10585	COG0653	protein targeting
CDO19_RS10735	COG3039	Transposase
CDO19_RS10810	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CDO19_RS10820	COG0131	Imidazoleglycerol-phosphate dehydratase
CDO19_RS10820	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CDO19_RS10835	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDO19_RS10855	COG0124	histidyl-tRNA synthetase
CDO19_RS10875	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CDO19_RS10910	COG1012	belongs to the aldehyde dehydrogenase family
CDO19_RS10935	COG0697	spore germination
CDO19_RS10945	COG1794	racemase activity, acting on amino acids and derivatives
CDO19_RS10970	COG0671	phosphoesterase, PA-phosphatase related
CDO19_RS10985	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CDO19_RS11000	COG2183	response to ionizing radiation
CDO19_RS11010	COG0723	plastoquinol--plastocyanin reductase activity
CDO19_RS11010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO19_RS11025	COG3243	poly(R)-hydroxyalkanoic acid synthase
CDO19_RS11035	COG1183	phosphatidylcholine synthase activity
CDO19_RS11040	COG1028	Short-chain dehydrogenase reductase Sdr
CDO19_RS11095	COG0668	transmembrane transport
CDO19_RS11115	COG1914	H( )-stimulated, divalent metal cation uptake system
CDO19_RS11140	COG0583	DNA-binding transcription factor activity
CDO19_RS11170	COG0583	DNA-binding transcription factor activity
CDO19_RS11175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDO19_RS11180	COG3002	Belongs to the UPF0753 family
CDO19_RS11195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDO19_RS11215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDO19_RS11225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDO19_RS11230	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CDO19_RS11240	COG0776	regulation of translation
CDO19_RS11245	COG0539	negative regulation of cytoplasmic translation
CDO19_RS11250	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CDO19_RS11265	COG2957	Belongs to the agmatine deiminase family
CDO19_RS11275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDO19_RS11295	COG0395	ABC-type sugar transport system, permease component
CDO19_RS11300	COG1175	transmembrane transport
CDO19_RS11330	COG2350	Protein conserved in bacteria
CDO19_RS11335	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDO19_RS11340	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDO19_RS11345	COG1187	pseudouridine synthase activity
CDO19_RS11370	COG0436	Aminotransferase
CDO19_RS11435	COG0277	FAD linked oxidase domain protein
CDO19_RS11440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDO19_RS11450	COG0531	amino acid
CDO19_RS11455	COG0531	amino acid
CDO19_RS11465	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CDO19_RS11560	COG0583	DNA-binding transcription factor activity
CDO19_RS11570	COG3039	Transposase
CDO19_RS11620	COG3039	Transposase
CDO19_RS11680	COG3039	Transposase
CDO19_RS11690	COG3039	Transposase
CDO19_RS11705	COG1278	Cold shock
CDO19_RS11715	COG3328	transposase activity
CDO19_RS11740	COG3039	Transposase
CDO19_RS11760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDO19_RS11780	COG0557	exoribonuclease II activity
CDO19_RS11810	COG1960	acyl-CoA dehydrogenase activity
CDO19_RS11815	COG2226	methyltransferase
CDO19_RS11820	COG1410	methionine synthase
CDO19_RS11820	COG0646	methionine synthase
CDO19_RS11825	COG1410	methionine synthase
CDO19_RS11825	COG0646	methionine synthase
CDO19_RS11835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO19_RS11845	COG1609	Transcriptional regulator
CDO19_RS11860	COG2900	Belongs to the SlyX family
CDO19_RS11875	COG0386	Belongs to the glutathione peroxidase family
CDO19_RS11885	COG1725	Transcriptional regulator
CDO19_RS11890	COG1131	(ABC) transporter
CDO19_RS11970	COG2850	peptidyl-arginine hydroxylation
CDO19_RS12005	COG1132	(ABC) transporter
CDO19_RS12020	COG0583	DNA-binding transcription factor activity
CDO19_RS12040	COG0287	Prephenate dehydrogenase
CDO19_RS12040	COG1605	Chorismate mutase
CDO19_RS12045	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CDO19_RS12055	COG0484	heat shock protein binding
CDO19_RS12060	COG0443	Heat shock 70 kDa protein
CDO19_RS12065	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CDO19_RS12075	COG0497	DNA recombination
CDO19_RS12085	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDO19_RS12095	COG2914	Belongs to the UPF0125 (RnfH) family
CDO19_RS12120	COG1960	acyl-CoA dehydrogenase activity
CDO19_RS12130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDO19_RS12175	COG2814	Major facilitator Superfamily
CDO19_RS12180	COG1566	PFAM secretion protein HlyD family protein
CDO19_RS12220	COG4774	siderophore transport
CDO19_RS12230	COG0367	asparagine synthase
CDO19_RS12245	COG1393	Belongs to the ArsC family
CDO19_RS12305	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDO19_RS12320	COG0233	cytoplasmic translational termination
CDO19_RS12330	COG0575	Belongs to the CDS family
CDO19_RS12340	COG0750	zinc metalloprotease
CDO19_RS12360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDO19_RS12365	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDO19_RS12385	COG0825	malonyl-CoA metabolic process
CDO19_RS12395	COG4771	TonB-dependent receptor
CDO19_RS12400	COG1131	(ABC) transporter
CDO19_RS12425	COG1981	membrane
CDO19_RS12470	COG2895	sulfate adenylyltransferase (ATP) activity
CDO19_RS12470	COG0529	Catalyzes the synthesis of activated sulfate
CDO19_RS12510	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CDO19_RS12525	COG2040	homocysteine
CDO19_RS12530	COG0833	amino acid
CDO19_RS12550	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO19_RS12550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO19_RS12560	COG2878	Part of a membrane complex involved in electron transport
CDO19_RS12580	COG1595	DNA-templated transcription, initiation
CDO19_RS12605	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDO19_RS12620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDO19_RS12625	COG0251	oxidation-reduction process
CDO19_RS12635	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CDO19_RS12635	COG0392	lysyltransferase activity
CDO19_RS12695	COG1902	pentaerythritol trinitrate reductase activity
CDO19_RS12710	COG2824	Alkylphosphonate utilization operon protein PhnA
CDO19_RS12725	COG1047	Peptidyl-prolyl cis-trans
CDO19_RS12770	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CDO19_RS12785	COG1451	nucleotide metabolic process
CDO19_RS12810	COG0183	Belongs to the thiolase family
CDO19_RS12840	COG1793	dna ligase
CDO19_RS12840	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CDO19_RS12850	COG1793	dna ligase
CDO19_RS12855	COG1201	RNA secondary structure unwinding
CDO19_RS12875	COG1278	Cold shock
CDO19_RS12880	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CDO19_RS12885	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CDO19_RS12895	COG3046	protein related to deoxyribodipyrimidine photolyase
CDO19_RS12900	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
CDO19_RS12905	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CDO19_RS12920	COG2954	triphosphatase activity
CDO19_RS12925	COG2954	triphosphatase activity
CDO19_RS12940	COG1381	Involved in DNA repair and RecF pathway recombination
CDO19_RS12970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO19_RS12985	COG1024	Enoyl-CoA hydratase
CDO19_RS12985	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO19_RS13010	COG1960	acyl-CoA dehydrogenase activity
CDO19_RS13085	COG2353	YceI-like domain
CDO19_RS13095	COG2353	YceI-like domain
CDO19_RS13110	COG1760	l-serine dehydratase
CDO19_RS13120	COG0626	cystathionine gamma-synthase activity
CDO19_RS13125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDO19_RS13130	COG0739	heme binding
CDO19_RS13140	COG1272	protein, Hemolysin III
CDO19_RS13160	COG0463	Glycosyl transferase, family 2
CDO19_RS13170	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CDO19_RS13180	COG4771	TonB-dependent receptor
CDO19_RS13185	COG1309	transcriptional regulator
CDO19_RS13195	COG1960	acyl-CoA dehydrogenase activity
CDO19_RS13230	COG0509	glycine decarboxylation via glycine cleavage system
CDO19_RS13245	COG0330	HflC and HflK could
CDO19_RS13260	COG3956	TIGRFAM MazG family protein
CDO19_RS13270	COG0494	nUDIX hydrolase
CDO19_RS13280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDO19_RS13285	COG0837	glucose binding
CDO19_RS13300	COG1388	LysM domain
CDO19_RS13300	COG3858	chitin binding
CDO19_RS13320	COG1472	Belongs to the glycosyl hydrolase 3 family
CDO19_RS13390	COG3537	Alpha-1,2-mannosidase
CDO19_RS13445	COG3142	Participates in the control of copper homeostasis
CDO19_RS13450	COG1446	asparaginase
CDO19_RS13495	COG2198	Histidine kinase
CDO19_RS13495	COG0784	Response regulator, receiver
CDO19_RS13495	COG0643	Histidine kinase
CDO19_RS13500	COG0840	transmembrane signaling receptor activity
CDO19_RS13505	COG0835	chemotaxis
CDO19_RS13520	COG0189	ligase activity
CDO19_RS13530	COG1397	ADP-ribosylglycohydrolase
CDO19_RS13540	COG1199	ATP-dependent helicase activity
CDO19_RS13550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDO19_RS13555	COG1215	transferase activity, transferring glycosyl groups
CDO19_RS13565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDO19_RS13620	COG1643	Atp-dependent helicase
CDO19_RS13625	COG0783	Belongs to the Dps family
CDO19_RS13635	COG0514	ATP-dependent DNA helicase (RecQ)
CDO19_RS13660	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CDO19_RS13720	COG1187	pseudouridine synthase activity
CDO19_RS13730	COG0602	queuosine metabolic process
CDO19_RS13740	COG2885	chlorophyll binding
CDO19_RS13755	COG0848	biopolymer transport protein
CDO19_RS13765	COG0824	Thioesterase
CDO19_RS13770	COG2255	four-way junction helicase activity
CDO19_RS13780	COG0632	four-way junction helicase activity
CDO19_RS13905	COG3209	COG3209 Rhs family protein
CDO19_RS13940	COG3209	COG3209 Rhs family protein
CDO19_RS13960	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CDO19_RS13965	COG1845	cytochrome c oxidase, subunit III
CDO19_RS13970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO19_RS13985	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDO19_RS13990	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDO19_RS14000	COG0196	riboflavin kinase activity
CDO19_RS14005	COG0728	peptidoglycan biosynthetic process
CDO19_RS14010	COG0268	Binds directly to 16S ribosomal RNA
CDO19_RS14015	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDO19_RS14020	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDO19_RS14030	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDO19_RS14035	COG0824	Thioesterase
CDO19_RS14050	COG1946	Acyl-CoA thioesterase
CDO19_RS14060	COG1595	DNA-templated transcription, initiation
CDO19_RS14080	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CDO19_RS14120	COG1877	trehalose-phosphatase activity
CDO19_RS14125	COG3387	PFAM Glycoside hydrolase 15-related
CDO19_RS14150	COG0564	pseudouridine synthase activity
CDO19_RS14155	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDO19_RS14160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDO19_RS14160	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDO19_RS14175	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CDO19_RS14180	COG0045	succinate-CoA ligase (ADP-forming) activity
CDO19_RS14220	COG2194	sulfuric ester hydrolase activity
CDO19_RS14225	COG4969	Belongs to the N-Me-Phe pilin family
CDO19_RS14235	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CDO19_RS14280	COG3039	Transposase
CDO19_RS14305	COG3039	Transposase
CDO19_RS14335	COG1132	(ABC) transporter
CDO19_RS14365	COG0745	RESPONSE REGULATOR receiver
CDO19_RS14370	COG5002	protein histidine kinase activity
CDO19_RS14370	COG5000	phosphorelay sensor kinase activity
CDO19_RS14375	COG0475	glutathione-regulated potassium exporter activity
CDO19_RS14385	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDO19_RS14410	COG1187	pseudouridine synthase activity
CDO19_RS14415	COG5002	protein histidine kinase activity
CDO19_RS14415	COG5001	Diguanylate cyclase
CDO19_RS14480	COG3039	Transposase
CDO19_RS14525	COG1028	Short-chain dehydrogenase reductase Sdr
CDO19_RS14545	COG0415	Belongs to the DNA photolyase family
CDO19_RS14550	COG0305	Participates in initiation and elongation during chromosome replication
CDO19_RS14560	COG0367	asparagine synthase
CDO19_RS14575	COG1960	acyl-CoA dehydrogenase activity
CDO19_RS14590	COG0084	hydrolase, TatD family'
CDO19_RS14595	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CDO19_RS14655	COG0735	belongs to the Fur family
CDO19_RS14660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDO19_RS14695	COG3039	Transposase
CDO19_RS14700	COG3039	Transposase
CDO19_RS14725	COG3039	Transposase
CDO19_RS14750	COG2205	protein histidine kinase activity
CDO19_RS14770	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CDO19_RS14780	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDO19_RS14795	COG0643	Histidine kinase
CDO19_RS14795	COG2198	Histidine kinase
CDO19_RS14800	COG0840	transmembrane signaling receptor activity
CDO19_RS14805	COG0835	chemotaxis
CDO19_RS14810	COG2202	Pas domain
CDO19_RS14810	COG2199	diguanylate cyclase activity
CDO19_RS14810	COG2200	EAL domain
CDO19_RS14815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CDO19_RS14830	COG3590	peptidase
CDO19_RS14850	COG1515	deoxyribonuclease V activity
CDO19_RS14855	COG1741	Belongs to the pirin family
CDO19_RS14970	COG1741	Belongs to the pirin family
CDO19_RS14975	COG1966	Carbon starvation protein
CDO19_RS14980	COG2879	small protein
CDO19_RS15020	COG2203	Gaf domain
CDO19_RS15020	COG5001	Diguanylate cyclase
CDO19_RS15020	COG3706	GGDEF domain
CDO19_RS15020	COG4251	negative regulation of phosphorylation
CDO19_RS15025	COG0629	single-stranded DNA binding
CDO19_RS15030	COG0142	geranyltranstransferase activity
CDO19_RS15060	COG0527	aspartate kinase activity
CDO19_RS15070	COG0384	phenazine biosynthesis protein PhzF
CDO19_RS15080	COG1764	response to oxidative stress
CDO19_RS15095	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDO19_RS15100	COG1678	Uncharacterized ACR, COG1678
CDO19_RS15110	COG0519	Catalyzes the synthesis of GMP from XMP
CDO19_RS15145	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CDO19_RS15190	COG0693	protein deglycase activity
CDO19_RS15210	COG1959	2 iron, 2 sulfur cluster binding
CDO19_RS15215	COG0719	Fe-S assembly protein
CDO19_RS15220	COG0396	ATPase activity
CDO19_RS15225	COG0719	Fe-S assembly protein
CDO19_RS15230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDO19_RS15245	COG2146	nitrite reductase [NAD(P)H] activity
CDO19_RS15280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDO19_RS15290	COG3039	Transposase
CDO19_RS15305	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CDO19_RS15315	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CDO19_RS15320	COG0174	glutamine synthetase
CDO19_RS15325	COG3328	transposase activity
CDO19_RS15355	COG0326	Molecular chaperone. Has ATPase activity
CDO19_RS15360	COG2207	Transcriptional regulator
CDO19_RS15385	COG2755	lipolytic protein G-D-S-L family
CDO19_RS15385	COG0657	acetylesterase activity
CDO19_RS15410	COG0488	(ABC) transporter
CDO19_RS15445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDO19_RS15445	COG4651	solute:proton antiporter activity
CDO19_RS15460	COG4772	TonB-dependent receptor
CDO19_RS15470	COG4264	IucA IucC family
CDO19_RS15485	COG0019	diaminopimelate decarboxylase activity
CDO19_RS15545	COG4206	TonB-dependent receptor
CDO19_RS15585	COG0542	response to heat
CDO19_RS15625	COG0534	Mate efflux family protein
CDO19_RS15640	COG0336	Belongs to the RNA methyltransferase TrmD family
CDO19_RS15645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDO19_RS15650	COG0228	four-way junction DNA binding
CDO19_RS15675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDO19_RS15685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDO19_RS15730	COG1555	photosystem II stabilization
CDO19_RS15735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDO19_RS15750	COG3178	'Phosphotransferase
CDO19_RS15755	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDO19_RS15765	COG0628	permease
CDO19_RS15775	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDO19_RS15790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDO19_RS15810	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDO19_RS15820	COG0271	Belongs to the BolA IbaG family
CDO19_RS15830	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CDO19_RS15840	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CDO19_RS15845	COG1137	ATPase activity
CDO19_RS15860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO19_RS15865	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CDO19_RS15870	COG1660	Displays ATPase and GTPase activities
CDO19_RS15880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO19_RS15885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDO19_RS15895	COG2239	Acts as a magnesium transporter
CDO19_RS15905	COG1294	oxidase, subunit
CDO19_RS15910	COG1271	oxidase subunit
CDO19_RS15930	COG1113	amino acid transport
CDO19_RS15945	COG2197	response regulator
CDO19_RS15950	COG0531	amino acid
CDO19_RS16020	COG0754	glutathionylspermidine amidase activity
CDO19_RS16045	COG1842	Phage shock protein A
CDO19_RS16060	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CDO19_RS16065	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CDO19_RS16075	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CDO19_RS16170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO19_RS16175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO19_RS16230	COG1858	cytochrome C peroxidase
CDO19_RS16270	COG0515	serine threonine protein kinase
CDO19_RS16275	COG0631	protein serine/threonine phosphatase activity
CDO19_RS16395	COG3039	Transposase
CDO19_RS16415	COG3039	Transposase
CDO19_RS16460	COG0316	Belongs to the HesB IscA family
CDO19_RS16460	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CDO19_RS16465	COG2154	pterin-4-alpha-carbinolamine dehydratase
CDO19_RS16475	COG0428	transporter
CDO19_RS16480	COG0428	transporter
CDO19_RS16485	COG3064	Membrane
CDO19_RS16495	COG1530	ribonuclease E activity
CDO19_RS16515	COG1054	Belongs to the UPF0176 family
CDO19_RS16520	COG3039	Transposase
CDO19_RS16540	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CDO19_RS16580	COG3039	Transposase
CDO19_RS16585	COG3039	Transposase
CDO19_RS16615	COG1648	precorrin-2 dehydrogenase activity
CDO19_RS16615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDO19_RS16640	COG0746	molybdenum cofactor guanylyltransferase activity
CDO19_RS16720	COG4206	TonB-dependent receptor
CDO19_RS16750	COG4206	TonB-dependent receptor
CDO19_RS16800	COG0531	amino acid
CDO19_RS16815	COG0006	proline dipeptidase activity
CDO19_RS16825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO19_RS16840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO19_RS16845	COG3938	Belongs to the proline racemase family
CDO19_RS16855	COG0552	protein localization to endoplasmic reticulum
CDO19_RS16880	COG4191	Histidine kinase
CDO19_RS16880	COG0784	Response regulator, receiver
CDO19_RS16970	COG3040	lipid binding
CDO19_RS17010	COG0438	transferase activity, transferring glycosyl groups
CDO19_RS17020	COG0438	transferase activity, transferring glycosyl groups
CDO19_RS17025	COG0438	transferase activity, transferring glycosyl groups
CDO19_RS17095	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CDO19_RS17130	COG4969	Belongs to the N-Me-Phe pilin family
CDO19_RS17170	COG1611	Belongs to the LOG family
CDO19_RS17185	COG2095	MarC family integral membrane protein
CDO19_RS17195	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CDO19_RS17230	COG1185	polyribonucleotide nucleotidyltransferase activity
CDO19_RS17235	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDO19_RS17255	COG0195	Participates in both transcription termination and antitermination
CDO19_RS17260	COG0779	Required for maturation of 30S ribosomal subunits
CDO19_RS17270	COG1007	ATP synthesis coupled electron transport
CDO19_RS17300	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CDO19_RS17305	COG1034	ATP synthesis coupled electron transport
CDO19_RS17310	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CDO19_RS17315	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CDO19_RS17320	COG0649	NAD binding
CDO19_RS17325	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDO19_RS17335	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDO19_RS17350	COG0149	triose-phosphate isomerase activity
CDO19_RS17405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDO19_RS17410	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CDO19_RS17435	COG0135	phosphoribosylanthranilate isomerase activity
CDO19_RS17440	COG0101	tRNA pseudouridine synthase activity
CDO19_RS17460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CDO19_RS17465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO19_RS17470	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CDO19_RS17475	COG2890	protein-(glutamine-N5) methyltransferase activity
CDO19_RS17530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO19_RS17540	COG0412	Dienelactone hydrolase
CDO19_RS17565	COG0717	Belongs to the dCTP deaminase family
CDO19_RS17570	COG0489	protein tyrosine kinase activity
CDO19_RS17615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO19_RS17620	COG2311	Membrane
CDO19_RS17625	COG1047	Peptidyl-prolyl cis-trans
CDO19_RS17630	COG0791	NLP P60 protein
CDO19_RS17635	COG0791	NLP P60 protein
CDO19_RS17655	COG1301	dicarboxylic acid transport
CDO19_RS17660	COG1785	Belongs to the alkaline phosphatase family
CDO19_RS17665	COG0037	tRNA processing
CDO19_RS17670	COG1722	exodeoxyribonuclease VII activity
CDO19_RS17675	COG0142	geranyltranstransferase activity
CDO19_RS17700	COG0312	modulator of DNA gyrase
CDO19_RS17705	COG3028	Belongs to the UPF0307 family
CDO19_RS17710	COG0312	modulator of DNA gyrase
CDO19_RS17720	COG3164	Protein of unknown function
CDO19_RS17735	COG2968	Membrane
CDO19_RS17760	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CDO19_RS17785	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDO19_RS17815	COG3118	belongs to the thioredoxin family
CDO19_RS17900	COG3039	Transposase
CDO19_RS17905	COG3039	Transposase
CDO19_RS18000	COG2022	thiamine diphosphate biosynthetic process
CDO19_RS18015	COG0471	metal ion transport
CDO19_RS18015	COG3273	potassium ion transport
CDO19_RS18045	COG1970	mechanosensitive ion channel activity
CDO19_RS18070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDO19_RS18105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO19_RS18120	COG2895	sulfate adenylyltransferase (ATP) activity
CDO19_RS18120	COG0529	Catalyzes the synthesis of activated sulfate
CDO19_RS18125	COG0175	sulfate reduction
CDO19_RS18130	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDO19_RS18135	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDO19_RS18140	COG0175	sulfate reduction
CDO19_RS18160	COG2205	protein histidine kinase activity
CDO19_RS18160	COG2198	Histidine kinase
CDO19_RS18160	COG0784	Response regulator, receiver
CDO19_RS18210	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CDO19_RS18215	COG3588	fructose-bisphosphate aldolase
CDO19_RS18220	COG0469	pyruvate kinase activity
CDO19_RS18260	COG0753	catalase activity
CDO19_RS18285	COG3039	Transposase
CDO19_RS18305	COG1917	Cupin 2, conserved barrel domain protein
CDO19_RS18305	COG2207	Transcriptional regulator
CDO19_RS18335	COG1506	peptidase
CDO19_RS18335	COG0823	Involved in the tonB-independent uptake of proteins
CDO19_RS18360	COG3039	Transposase
CDO19_RS18365	COG1297	OPT oligopeptide transporter protein
CDO19_RS18470	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CDO19_RS18485	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
CDO19_RS18490	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
CDO19_RS18495	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CDO19_RS18515	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CDO19_RS18675	COG3179	chitinase
CDO19_RS18795	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDO19_RS18850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDO19_RS18860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDO19_RS18950	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CDO19_RS18965	COG2197	response regulator
CDO19_RS18970	COG4585	Histidine kinase
CDO19_RS18990	COG2894	cell division
CDO19_RS18995	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CDO19_RS19005	COG0642	Histidine kinase
CDO19_RS19010	COG0745	RESPONSE REGULATOR receiver
CDO19_RS19015	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDO19_RS19025	COG2194	sulfuric ester hydrolase activity
CDO19_RS19055	COG3551	Protein conserved in bacteria
CDO19_RS19120	COG0203	ribosomal protein L17
CDO19_RS19130	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDO19_RS19135	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDO19_RS19145	COG0201	protein transport
CDO19_RS19155	COG1841	ribosomal large subunit assembly
CDO19_RS19185	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDO19_RS19195	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CDO19_RS19200	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDO19_RS19205	COG0255	Belongs to the universal ribosomal protein uL29 family
CDO19_RS19210	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CDO19_RS19220	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDO19_RS19235	COG0089	rRNA binding
CDO19_RS19240	COG0088	Forms part of the polypeptide exit tunnel
CDO19_RS19245	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDO19_RS19250	COG0051	transcription antitermination factor activity, RNA binding
CDO19_RS19270	COG0049	tRNA binding
CDO19_RS19275	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDO19_RS19280	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDO19_RS19285	COG0085	RNA polymerase activity
CDO19_RS19290	COG0222	ribosome binding
CDO19_RS19295	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDO19_RS19305	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDO19_RS19315	COG0250	Participates in transcription elongation, termination and antitermination
CDO19_RS19320	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CDO19_RS19350	COG0012	GTP binding
CDO19_RS19355	COG0193	aminoacyl-tRNA hydrolase activity
CDO19_RS19365	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDO19_RS19380	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CDO19_RS19395	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDO19_RS19405	COG0521	Mo-molybdopterin cofactor biosynthetic process
CDO19_RS19425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO19_RS19430	COG1295	ribonuclease BN
CDO19_RS19460	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDO19_RS19470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDO19_RS19500	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CDO19_RS19525	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CDO19_RS19540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDO19_RS19540	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDO19_RS19590	COG2890	protein-(glutamine-N5) methyltransferase activity
CDO19_RS19600	COG3634	alkyl hydroperoxide reductase activity
CDO19_RS19605	COG0583	DNA-binding transcription factor activity
CDO19_RS19615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO19_RS19695	COG4783	chaperone-mediated protein folding
CDO19_RS19710	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CDO19_RS19725	COG0671	phosphoesterase, PA-phosphatase related
CDO19_RS19730	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDO19_RS19750	COG2833	Protein of unknown function (DUF455)
CDO19_RS19770	COG0285	dihydrofolate synthase activity
CDO19_RS19780	COG0406	alpha-ribazole phosphatase activity
CDO19_RS19815	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDO19_RS19820	COG4208	sulfate ABC transporter
CDO19_RS19825	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CDO19_RS19830	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDO19_RS19835	COG0156	8-amino-7-oxononanoate synthase activity
CDO19_RS19865	COG0604	alcohol dehydrogenase
CDO19_RS19870	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDO19_RS19870	COG1902	pentaerythritol trinitrate reductase activity
CDO19_RS20010	COG3386	PFAM SMP-30 Gluconolaconase
CDO19_RS20030	COG1024	Enoyl-CoA hydratase
CDO19_RS20040	COG0318	PFAM AMP-dependent synthetase and ligase
CDO19_RS20045	COG0583	DNA-binding transcription factor activity
CDO19_RS20085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDO19_RS20090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDO19_RS20100	COG2096	Adenosyltransferase
CDO19_RS20105	COG0123	including yeast histone deacetylase and acetoin utilization protein
CDO19_RS20120	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDO19_RS20130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDO19_RS20135	COG2967	ApaG domain
CDO19_RS20160	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CDO19_RS20180	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CDO19_RS20195	COG0642	Histidine kinase
CDO19_RS20210	COG4181	ATPase activity
CDO19_RS20220	COG2175	clavaminate synthase activity
CDO19_RS20230	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CDO19_RS20270	COG0667	Aldo Keto reductase
CDO19_RS20280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CDO19_RS20285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO19_RS20300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDO19_RS20315	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDO19_RS20370	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CDO19_RS20375	COG2226	methyltransferase
CDO19_RS20430	COG3321	synthase
CDO19_RS20430	COG1028	Short-chain dehydrogenase reductase Sdr
CDO19_RS20430	COG0604	alcohol dehydrogenase
CDO19_RS20445	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CDO19_RS20460	COG0494	nUDIX hydrolase
CDO19_RS20475	COG4942	peptidase
CDO19_RS20475	COG1388	LysM domain
CDO19_RS20485	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CDO19_RS20500	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CDO19_RS20505	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDO19_RS20510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDO19_RS20525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDO19_RS20530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDO19_RS20545	COG3116	cell division
CDO19_RS20550	COG0275	rRNA processing
CDO19_RS20585	COG0792	nuclease activity
CDO19_RS20590	COG1988	membrane-bound metal-dependent
CDO19_RS20595	COG0277	FAD linked oxidase domain protein
CDO19_RS20600	COG0745	RESPONSE REGULATOR receiver
CDO19_RS20605	COG2205	protein histidine kinase activity
CDO19_RS20615	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CDO19_RS20620	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CDO19_RS20645	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CDO19_RS20650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDO19_RS20655	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CDO19_RS20675	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDO19_RS20675	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDO19_RS20695	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDO19_RS20715	COG0488	(ABC) transporter
CDO19_RS20765	COG2205	protein histidine kinase activity
CDO19_RS20805	COG2205	protein histidine kinase activity
CDO19_RS20825	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CDO19_RS20860	COG3039	Transposase
CDO19_RS20865	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDO19_RS20880	COG3039	Transposase
CDO19_RS20935	COG3039	Transposase
CDO19_RS20985	COG1649	PFAM Uncharacterised BCR, COG1649
CDO19_RS20985	COG0726	polysaccharide deacetylase
CDO19_RS20990	COG1215	transferase activity, transferring glycosyl groups
CDO19_RS21000	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CDO19_RS21005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDO19_RS21010	COG1609	Transcriptional regulator
CDO19_RS21020	COG2188	Transcriptional regulator
CDO19_RS21035	COG3250	beta-galactosidase activity
CDO19_RS21090	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CDO19_RS21095	COG4191	Histidine kinase
CDO19_RS21100	COG0784	Response regulator, receiver
CDO19_RS21105	COG4251	negative regulation of phosphorylation
CDO19_RS21110	COG2823	Periplasmic or secreted lipoprotein
CDO19_RS21115	COG0673	inositol 2-dehydrogenase activity
CDO19_RS21120	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CDO19_RS21155	COG1056	cytidyltransferase-related domain
CDO19_RS21155	COG1051	belongs to the nudix hydrolase family
CDO19_RS21190	COG2921	Belongs to the UPF0250 family
CDO19_RS21205	COG1686	Belongs to the peptidase S11 family
CDO19_RS21210	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CDO19_RS21215	COG2951	lytic endotransglycosylase activity
CDO19_RS21235	COG3409	Peptidoglycan-binding domain 1 protein
CDO19_RS21235	COG1388	LysM domain
CDO19_RS21235	COG5632	N-Acetylmuramoyl-L-alanine amidase
CDO19_RS21275	COG0772	Belongs to the SEDS family
CDO19_RS21290	COG1792	Involved in formation and maintenance of cell shape
CDO19_RS21295	COG1077	Cell shape determining protein MreB Mrl
CDO19_RS21300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO19_RS21305	COG3039	Transposase
CDO19_RS21355	COG2199	diguanylate cyclase activity
CDO19_RS21360	COG0308	aminopeptidase N
CDO19_RS21390	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CDO19_RS21420	COG0436	Aminotransferase
CDO19_RS21435	COG1505	serine-type exopeptidase activity
CDO19_RS21460	COG0181	hydroxymethylbilane synthase activity
CDO19_RS21470	COG3275	phosphorelay sensor kinase activity
CDO19_RS21515	COG0659	secondary active sulfate transmembrane transporter activity
CDO19_RS21520	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CDO19_RS21520	COG5297	Belongs to the glycosyl hydrolase family 6
CDO19_RS21595	COG0598	Magnesium transport protein CorA
CDO19_RS21605	COG1113	amino acid transport
CDO19_RS21615	COG5297	Belongs to the glycosyl hydrolase family 6
CDO19_RS21620	COG4305	rare lipoprotein A
CDO19_RS21625	COG0697	spore germination
CDO19_RS21685	COG4221	oxidoreductase activity
CDO19_RS21715	COG0456	acetyltransferase
CDO19_RS21725	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CDO19_RS21760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDO19_RS21760	COG2111	Na H antiporter
CDO19_RS21765	COG1006	Multisubunit Na H antiporter MnhC subunit
CDO19_RS21770	COG0651	ATP synthesis coupled electron transport
CDO19_RS21780	COG2212	antiporter activity
CDO19_RS21785	COG1320	monovalent cation:proton antiporter activity
CDO19_RS21800	COG3039	Transposase
CDO19_RS21805	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CDO19_RS21825	COG3104	oligopeptide transport
CDO19_RS21830	COG3483	tryptophan 2,3-dioxygenase activity
CDO19_RS21840	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDO19_RS21875	COG0183	Belongs to the thiolase family
CDO19_RS21930	COG3039	Transposase
CDO19_RS21965	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CDO19_RS21970	COG3023	N-Acetylmuramoyl-L-alanine amidase
CDO19_RS21980	COG4948	Mandelate Racemase Muconate Lactonizing
CDO19_RS22020	COG0531	amino acid
CDO19_RS22055	COG4682	membrane
CDO19_RS22060	COG3039	Transposase
CDO19_RS22065	COG2133	pyrroloquinoline quinone binding
CDO19_RS22105	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDO19_RS22110	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDO19_RS22120	COG1610	YqeY-like protein
CDO19_RS22135	COG1295	ribonuclease BN
CDO19_RS22140	COG0358	DNA primase activity
CDO19_RS22205	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CDO19_RS22220	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDO19_RS22270	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDO19_RS22275	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDO19_RS22280	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CDO19_RS22290	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CDO19_RS22295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDO19_RS22310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDO19_RS22390	COG3039	Transposase
CDO19_RS22405	COG3328	transposase activity
CDO19_RS22420	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CDO19_RS22420	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CDO19_RS22430	COG1473	amidohydrolase
CDO19_RS22435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO19_RS22440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO19_RS22455	COG5383	Protein conserved in bacteria
CDO19_RS22500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDO19_RS22505	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CDO19_RS22520	COG0028	Belongs to the TPP enzyme family
CDO19_RS22525	COG4191	Histidine kinase
CDO19_RS22550	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDO19_RS22565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDO19_RS22570	COG3177	Filamentation induced by cAMP protein fic
CDO19_RS22585	COG0596	Alpha beta hydrolase
CDO19_RS22590	COG0727	PFAM Uncharacterised protein family (UPF0153)
CDO19_RS22595	COG0318	PFAM AMP-dependent synthetase and ligase
CDO19_RS22600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO19_RS22660	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDO19_RS22670	COG0129	dihydroxy-acid dehydratase activity
CDO19_RS22710	COG0408	coproporphyrinogen oxidase activity
CDO19_RS22765	COG3039	Transposase
CDO19_RS22815	COG2353	YceI-like domain
CDO19_RS22845	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CDO19_RS22860	COG3386	PFAM SMP-30 Gluconolaconase
CDO19_RS22895	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDO19_RS22910	COG4771	TonB-dependent receptor
CDO19_RS22920	COG0459	protein refolding
CDO19_RS22945	COG1252	NADH dehydrogenase
CDO19_RS22955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDO19_RS22960	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDO19_RS22965	COG3437	response regulator, receiver
CDO19_RS22970	COG2177	Part of the ABC transporter FtsEX involved in
CDO19_RS22975	COG2884	Cell division ATP-binding protein ftsE
CDO19_RS22985	COG3118	belongs to the thioredoxin family
CDO19_RS22990	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CDO19_RS23005	COG0729	surface antigen
CDO19_RS23010	COG2911	Protein conserved in bacteria
CDO19_RS23045	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDO19_RS23060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO19_RS23120	COG1733	regulation of RNA biosynthetic process
CDO19_RS23125	COG0702	epimerase
CDO19_RS23155	COG0583	DNA-binding transcription factor activity
CDO19_RS23160	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDO19_RS23180	COG0745	RESPONSE REGULATOR receiver
CDO19_RS23210	COG1902	pentaerythritol trinitrate reductase activity
CDO19_RS23215	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CDO19_RS23225	COG2814	Major facilitator Superfamily
CDO19_RS23230	COG0583	DNA-binding transcription factor activity
CDO19_RS23250	COG0084	hydrolase, TatD family'
CDO19_RS23300	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDO19_RS23320	COG2072	flavoprotein involved in K transport
CDO19_RS23375	COG4770	biotin carboxylase activity
CDO19_RS23380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDO19_RS23385	COG1960	acyl-CoA dehydrogenase activity
CDO19_RS23440	COG0523	cobalamin synthesis protein
CDO19_RS23460	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CDO19_RS23480	COG0457	Tetratricopeptide repeat
CDO19_RS23495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDO19_RS23525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDO19_RS23525	COG0519	Catalyzes the synthesis of GMP from XMP
CDO19_RS23535	COG0805	protein transport
CDO19_RS23545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDO19_RS23555	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CDO19_RS23605	COG3661	Belongs to the glycosyl hydrolase 67 family
CDO19_RS23615	COG4948	Mandelate Racemase Muconate Lactonizing
CDO19_RS23625	COG1472	Belongs to the glycosyl hydrolase 3 family
CDO19_RS23630	COG0246	Mannitol dehydrogenase
CDO19_RS23655	COG3693	PFAM glycoside hydrolase, family 10
CDO19_RS23680	COG2211	Major facilitator Superfamily
CDO19_RS23725	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CDO19_RS23775	COG1846	Transcriptional regulator
CDO19_RS23780	COG1764	response to oxidative stress
CDO19_RS23880	COG3549	Plasmid maintenance system killer
CDO19_RS23890	COG1074	ATP-dependent DNA helicase activity
CDO19_RS23895	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CDO19_RS23905	COG1196	nuclear chromosome segregation
CDO19_RS23945	COG2032	superoxide dismutase activity
CDO19_RS23950	COG2032	superoxide dismutase activity
CDO19_RS23955	COG2204	response regulator
CDO19_RS23960	COG3852	Histidine kinase
CDO19_RS23965	COG0004	ammonium transporteR
CDO19_RS23970	COG0347	Belongs to the P(II) protein family
CDO19_RS23975	COG0174	glutamine synthetase
CDO19_RS23980	COG1968	undecaprenyl-diphosphatase activity
CDO19_RS24025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDO19_RS24035	COG2062	phosphohistidine phosphatase, SixA
CDO19_RS24040	COG0489	protein tyrosine kinase activity
CDO19_RS24060	COG1396	sequence-specific DNA binding
CDO19_RS24065	COG3550	peptidyl-serine autophosphorylation
CDO19_RS24070	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CDO19_RS24075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDO19_RS24090	COG0517	IMP dehydrogenase activity
CDO19_RS24090	COG1125	glycine betaine transport
CDO19_RS24105	COG1119	ATPase activity
CDO19_RS24115	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDO19_RS24130	COG3039	Transposase
CDO19_RS24155	COG0656	L-ascorbic acid biosynthetic process
CDO19_RS24160	COG2130	NADP-dependent
CDO19_RS24165	COG0667	Aldo Keto reductase
CDO19_RS24175	COG1187	pseudouridine synthase activity
CDO19_RS24190	COG1643	Atp-dependent helicase
CDO19_RS24195	COG4807	Protein conserved in bacteria
CDO19_RS24200	COG4948	Mandelate Racemase Muconate Lactonizing
CDO19_RS24210	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDO19_RS24215	COG1028	Short-chain dehydrogenase reductase Sdr
CDO19_RS24235	COG3507	Belongs to the glycosyl hydrolase 43 family
CDO19_RS24275	COG3162	membrane
CDO19_RS24280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDO19_RS24295	COG0708	Exodeoxyribonuclease III
CDO19_RS24310	COG2091	lysine biosynthetic process via aminoadipic acid
CDO19_RS24320	COG3540	Alkaline phosphatase
CDO19_RS24350	COG2159	amidohydrolase
CDO19_RS24375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDO19_RS24380	COG0583	DNA-binding transcription factor activity
CDO19_RS24385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDO19_RS24405	COG0210	DNA helicase
CDO19_RS24420	COG0531	amino acid
CDO19_RS24430	COG1322	Protein conserved in bacteria
CDO19_RS24440	COG0386	Belongs to the glutathione peroxidase family
CDO19_RS24495	COG0793	Belongs to the peptidase S41A family
CDO19_RS24500	COG4942	peptidase
CDO19_RS24510	COG2234	aminopeptidase activity
CDO19_RS24560	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDO19_RS24565	COG0302	gtp cyclohydrolase
CDO19_RS24590	COG0477	Major facilitator Superfamily
CDO19_RS24695	COG1929	Belongs to the glycerate kinase type-1 family
CDO19_RS24700	COG2271	Major facilitator Superfamily
CDO19_RS24715	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CDO19_RS24725	COG0861	Integral membrane protein TerC family
CDO19_RS24735	COG0584	glycerophosphoryl diester phosphodiesterase
CDO19_RS24745	COG0671	phosphoesterase, PA-phosphatase related
CDO19_RS24755	COG0726	polysaccharide deacetylase