locus-tag	class	description
CDO11_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDO11_RS00030	COG0187	DNA topoisomerase II activity
CDO11_RS00040	COG0501	Belongs to the peptidase M48B family
CDO11_RS00080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDO11_RS00090	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CDO11_RS00100	COG4772	TonB-dependent receptor
CDO11_RS00115	COG3039	Transposase
CDO11_RS00120	COG1304	FMN binding
CDO11_RS00125	COG1755	Isoprenylcysteine carboxyl methyltransferase
CDO11_RS00150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO11_RS00160	COG3039	Transposase
CDO11_RS00165	COG1136	(ABC) transporter
CDO11_RS00215	COG3039	Transposase
CDO11_RS00225	COG0513	Belongs to the DEAD box helicase family
CDO11_RS00325	COG1858	cytochrome C peroxidase
CDO11_RS00335	COG0702	epimerase
CDO11_RS00360	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CDO11_RS00380	COG1649	PFAM Uncharacterised BCR, COG1649
CDO11_RS00385	COG2354	Protein conserved in bacteria
CDO11_RS00395	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDO11_RS00450	COG3039	Transposase
CDO11_RS00500	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDO11_RS00580	COG3039	Transposase
CDO11_RS00595	COG3039	Transposase
CDO11_RS00635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO11_RS00645	COG0642	Histidine kinase
CDO11_RS00655	COG1090	epimerase
CDO11_RS00665	COG3039	Transposase
CDO11_RS00690	COG2826	transposase and inactivated derivatives, IS30 family
CDO11_RS00750	COG1136	(ABC) transporter
CDO11_RS00795	COG1272	protein, Hemolysin III
CDO11_RS00800	COG1205	dead DEAH box helicase
CDO11_RS00800	COG1111	helicase
CDO11_RS00865	COG0070	glutamate synthase
CDO11_RS00865	COG0069	glutamate synthase activity
CDO11_RS00865	COG0067	glutamate synthase
CDO11_RS00870	COG0493	'glutamate synthase
CDO11_RS00920	COG1609	Transcriptional regulator
CDO11_RS00955	COG0366	Alpha amylase catalytic
CDO11_RS00960	COG0366	Alpha amylase catalytic
CDO11_RS01015	COG0606	chelatase, subunit chli
CDO11_RS01060	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CDO11_RS01065	COG1166	arginine decarboxylase activity
CDO11_RS01130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDO11_RS01155	COG1028	Short-chain dehydrogenase reductase Sdr
CDO11_RS01180	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CDO11_RS01195	COG0210	DNA helicase
CDO11_RS01210	COG3132	Protein of unknown function, DUF480
CDO11_RS01215	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CDO11_RS01220	COG0284	orotidine-5'-phosphate decarboxylase activity
CDO11_RS01255	COG2937	Belongs to the GPAT DAPAT family
CDO11_RS01285	COG2755	lipolytic protein G-D-S-L family
CDO11_RS01300	COG3186	Phenylalanine-4-hydroxylase
CDO11_RS01305	COG1522	sequence-specific DNA binding
CDO11_RS01355	COG1064	alcohol dehydrogenase
CDO11_RS01365	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CDO11_RS01375	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CDO11_RS01385	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CDO11_RS01410	COG3039	Transposase
CDO11_RS01415	COG0676	glucose-6-phosphate 1-epimerase activity
CDO11_RS01480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CDO11_RS01505	COG2853	Lipoprotein
CDO11_RS01520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CDO11_RS01525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDO11_RS01530	COG1127	ABC transporter
CDO11_RS01605	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDO11_RS01620	COG3265	gluconokinase activity
CDO11_RS01625	COG2211	Major facilitator Superfamily
CDO11_RS01630	COG3459	Glycosyltransferase 36 associated
CDO11_RS01645	COG2205	protein histidine kinase activity
CDO11_RS01655	COG1414	Transcriptional regulator
CDO11_RS01660	COG0738	Major facilitator superfamily
CDO11_RS01665	COG3254	rhamnose metabolic process
CDO11_RS01695	COG0339	signal peptide processing
CDO11_RS01725	COG0564	pseudouridine synthase activity
CDO11_RS01735	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDO11_RS01835	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CDO11_RS01845	COG0842	Transport permease protein
CDO11_RS01850	COG1131	(ABC) transporter
CDO11_RS01855	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDO11_RS01875	COG1476	TRANSCRIPTIONal
CDO11_RS01885	COG4555	ABC transporter
CDO11_RS01920	COG0625	glutathione transferase activity
CDO11_RS01980	COG0583	DNA-binding transcription factor activity
CDO11_RS02015	COG1199	ATP-dependent helicase activity
CDO11_RS02040	COG1566	PFAM secretion protein HlyD family protein
CDO11_RS02070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDO11_RS02110	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CDO11_RS02110	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CDO11_RS02115	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CDO11_RS02130	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CDO11_RS02170	COG3237	CsbD-like
CDO11_RS02175	COG0180	Tryptophanyl-tRNA synthetase
CDO11_RS02180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO11_RS02230	COG0753	catalase activity
CDO11_RS02235	COG1595	DNA-templated transcription, initiation
CDO11_RS02245	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CDO11_RS02255	COG0628	permease
CDO11_RS02270	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDO11_RS02275	COG1040	competence protein
CDO11_RS02280	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDO11_RS02285	COG0156	8-amino-7-oxononanoate synthase activity
CDO11_RS02300	COG1028	Short-chain dehydrogenase reductase Sdr
CDO11_RS02315	COG0463	Glycosyl transferase, family 2
CDO11_RS02325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDO11_RS02330	COG3100	YcgL domain-containing protein
CDO11_RS02345	COG3387	PFAM Glycoside hydrolase 15-related
CDO11_RS02350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CDO11_RS02370	COG2239	Acts as a magnesium transporter
CDO11_RS02380	COG1042	CoA-binding domain protein
CDO11_RS02380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO11_RS02380	COG0045	succinate-CoA ligase (ADP-forming) activity
CDO11_RS02390	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDO11_RS02400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDO11_RS02435	COG3485	protocatechuate 3,4-dioxygenase
CDO11_RS02440	COG3485	protocatechuate 3,4-dioxygenase
CDO11_RS02450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CDO11_RS02455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDO11_RS02460	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDO11_RS02485	COG4221	oxidoreductase activity
CDO11_RS02510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDO11_RS02535	COG0463	Glycosyl transferase, family 2
CDO11_RS02550	COG1475	DNA binding
CDO11_RS02555	COG1192	Involved in chromosome partitioning
CDO11_RS02570	COG0708	Exodeoxyribonuclease III
CDO11_RS02575	COG2211	Major facilitator Superfamily
CDO11_RS02590	COG0739	heme binding
CDO11_RS02635	COG0745	RESPONSE REGULATOR receiver
CDO11_RS02680	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CDO11_RS02705	COG2814	Major facilitator Superfamily
CDO11_RS02720	COG1289	transmembrane transporter activity
CDO11_RS02730	COG0577	efflux transmembrane transporter activity
CDO11_RS02730	COG1136	(ABC) transporter
CDO11_RS02735	COG0151	Belongs to the GarS family
CDO11_RS02745	COG0419	ATPase involved in DNA repair
CDO11_RS02760	COG2267	carboxylic ester hydrolase activity
CDO11_RS02770	COG2267	carboxylic ester hydrolase activity
CDO11_RS02775	COG0671	phosphoesterase, PA-phosphatase related
CDO11_RS02775	COG2453	phosphatase
CDO11_RS02790	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CDO11_RS02850	COG0439	Biotin carboxylase
CDO11_RS02860	COG0511	ligase activity, forming carbon-carbon bonds
CDO11_RS02865	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CDO11_RS02885	COG1324	tolerance protein
CDO11_RS02920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDO11_RS02950	COG0534	Mate efflux family protein
CDO11_RS02955	COG0616	signal peptide processing
CDO11_RS02965	COG1028	Short-chain dehydrogenase reductase Sdr
CDO11_RS02980	COG0009	L-threonylcarbamoyladenylate synthase
CDO11_RS02985	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDO11_RS02985	COG1754	DNA topoisomerase type I activity
CDO11_RS03000	COG2922	Belongs to the Smg family
CDO11_RS03005	COG0758	DNA mediated transformation
CDO11_RS03010	COG1652	LysM domain
CDO11_RS03015	COG0242	peptide deformylase activity
CDO11_RS03020	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDO11_RS03025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDO11_RS03025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDO11_RS03075	COG1560	Kdo2-lipid A biosynthetic process
CDO11_RS03085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDO11_RS03320	COG1294	oxidase, subunit
CDO11_RS03325	COG1271	oxidase subunit
CDO11_RS03340	COG2204	response regulator
CDO11_RS03370	COG2972	Histidine kinase
CDO11_RS03385	COG0531	amino acid
CDO11_RS03405	COG3590	peptidase
CDO11_RS03420	COG0667	Aldo Keto reductase
CDO11_RS03435	COG3384	dioxygenase
CDO11_RS03445	COG1573	uracil-dna glycosylase
CDO11_RS03455	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CDO11_RS03470	COG0025	NhaP-type Na H and K H
CDO11_RS03475	COG1131	(ABC) transporter
CDO11_RS03480	COG0842	Transport permease protein
CDO11_RS03495	COG1404	Belongs to the peptidase S8 family
CDO11_RS03510	COG0745	RESPONSE REGULATOR receiver
CDO11_RS03560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO11_RS03585	COG2205	protein histidine kinase activity
CDO11_RS03585	COG2202	Pas domain
CDO11_RS03620	COG2813	Specifically methylates the guanine in position
CDO11_RS03625	COG1187	pseudouridine synthase activity
CDO11_RS03630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDO11_RS03665	COG0697	spore germination
CDO11_RS03675	COG2011	ABC-type metal ion transport system permease component
CDO11_RS03705	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO11_RS03715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDO11_RS03735	COG0356	it plays a direct role in the translocation of protons across the membrane
CDO11_RS03745	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDO11_RS03755	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDO11_RS03760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDO11_RS03765	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDO11_RS03770	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CDO11_RS03825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO11_RS03830	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDO11_RS03885	COG0339	signal peptide processing
CDO11_RS03925	COG1956	GAF domain-containing protein
CDO11_RS03930	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CDO11_RS03940	COG0720	synthase
CDO11_RS03950	COG0513	Belongs to the DEAD box helicase family
CDO11_RS03995	COG0626	cystathionine gamma-synthase activity
CDO11_RS04070	COG2086	electron transfer activity
CDO11_RS04095	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CDO11_RS04095	COG0662	Cupin 2, conserved barrel domain protein
CDO11_RS04100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDO11_RS04115	COG3039	Transposase
CDO11_RS04145	COG3218	ABC-type transport auxiliary lipoprotein component
CDO11_RS04145	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CDO11_RS04150	COG1127	ABC transporter
CDO11_RS04155	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDO11_RS04170	COG0442	prolyl-tRNA aminoacylation
CDO11_RS04180	COG1183	phosphatidylcholine synthase activity
CDO11_RS04210	COG3039	Transposase
CDO11_RS04280	COG0525	valine-tRNA ligase activity
CDO11_RS04295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CDO11_RS04305	COG0795	lipopolysaccharide-transporting ATPase activity
CDO11_RS04320	COG4974	Belongs to the 'phage' integrase family
CDO11_RS04325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDO11_RS04330	COG0047	phosphoribosylformylglycinamidine synthase activity
CDO11_RS04330	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDO11_RS04340	COG5295	Hep Hag repeat protein
CDO11_RS04360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDO11_RS04370	COG1459	type II secretion system
CDO11_RS04375	COG2165	general secretion pathway protein
CDO11_RS04380	COG4970	Tfp pilus assembly protein FimT
CDO11_RS04385	COG2165	general secretion pathway protein
CDO11_RS04390	COG4795	General secretion pathway protein
CDO11_RS04395	COG3156	type II secretion system protein K
CDO11_RS04400	COG3166	PFAM Fimbrial assembly family protein
CDO11_RS04415	COG1450	Type ii and iii secretion system protein
CDO11_RS04430	COG2188	Transcriptional regulator
CDO11_RS04490	COG3039	Transposase
CDO11_RS04495	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CDO11_RS04500	COG1518	maintenance of DNA repeat elements
CDO11_RS04545	COG1399	metal-binding, possibly nucleic acid-binding protein
CDO11_RS04570	COG1028	Short-chain dehydrogenase reductase Sdr
CDO11_RS04575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO11_RS04585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDO11_RS04590	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDO11_RS04615	COG3829	transcription factor binding
CDO11_RS04700	COG2826	transposase and inactivated derivatives, IS30 family
CDO11_RS04710	COG0678	peroxiredoxin activity
CDO11_RS04730	COG0330	HflC and HflK could
CDO11_RS04735	COG0330	HflC and HflK could
CDO11_RS04750	COG0308	aminopeptidase N
CDO11_RS04800	COG1560	Kdo2-lipid A biosynthetic process
CDO11_RS04805	COG1519	Transferase
CDO11_RS04810	COG1538	Outer membrane efflux protein
CDO11_RS04815	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO11_RS04840	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDO11_RS04845	COG0066	3-isopropylmalate dehydratase activity
CDO11_RS04880	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDO11_RS04890	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDO11_RS04895	COG3710	Transcriptional regulator
CDO11_RS04920	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CDO11_RS04940	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CDO11_RS04970	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDO11_RS04980	COG3781	membrane
CDO11_RS05000	COG0625	glutathione transferase activity
CDO11_RS05010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDO11_RS05015	COG1217	gtp-binding protein TYPA
CDO11_RS05035	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CDO11_RS05100	COG3039	Transposase
CDO11_RS05180	COG3039	Transposase
CDO11_RS05205	COG0584	glycerophosphoryl diester phosphodiesterase
CDO11_RS05230	COG0473	3-isopropylmalate dehydrogenase activity
CDO11_RS05280	COG0544	peptidyl-prolyl cis-trans isomerase activity
CDO11_RS05320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDO11_RS05345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDO11_RS05355	COG0631	protein serine/threonine phosphatase activity
CDO11_RS05440	COG0582	viral genome integration into host DNA
CDO11_RS05450	COG0859	PFAM glycosyl transferase family 9
CDO11_RS05455	COG3642	lipopolysaccharide core region biosynthetic process
CDO11_RS05460	COG1234	tRNA 3'-trailer cleavage
CDO11_RS05465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDO11_RS05475	COG0315	cyclic pyranopterin monophosphate synthase activity
CDO11_RS05480	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CDO11_RS05485	COG0314	molybdopterin synthase activity
CDO11_RS05515	COG0537	adenosine 5'-monophosphoramidase activity
CDO11_RS05535	COG0714	Associated with various cellular activities
CDO11_RS05555	COG0242	peptide deformylase activity
CDO11_RS05605	COG3039	Transposase
CDO11_RS05635	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CDO11_RS05640	COG0726	polysaccharide deacetylase
CDO11_RS05690	COG2211	Major facilitator Superfamily
CDO11_RS05700	COG1609	Transcriptional regulator
CDO11_RS05705	COG1028	Short-chain dehydrogenase reductase Sdr
CDO11_RS05710	COG2851	Citrate transporter
CDO11_RS05730	COG0642	Histidine kinase
CDO11_RS05740	COG2197	response regulator
CDO11_RS05760	COG0583	DNA-binding transcription factor activity
CDO11_RS05775	COG4191	Histidine kinase
CDO11_RS05795	COG0281	malic enzyme
CDO11_RS05795	COG0280	phosphate acetyltransferase
CDO11_RS05830	COG0352	thiamine-phosphate diphosphorylase activity
CDO11_RS05835	COG1773	rubredoxin
CDO11_RS05840	COG2912	Transglutaminase-like superfamily
CDO11_RS05860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDO11_RS05885	COG0006	proline dipeptidase activity
CDO11_RS05920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDO11_RS05935	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDO11_RS05940	COG1561	YicC-like family, N-terminal region
CDO11_RS05965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDO11_RS05975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDO11_RS06000	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDO11_RS06050	COG0714	Associated with various cellular activities
CDO11_RS06070	COG2304	oxidoreductase activity
CDO11_RS06090	COG1301	dicarboxylic acid transport
CDO11_RS06095	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDO11_RS06100	COG4773	Receptor
CDO11_RS06105	COG0739	heme binding
CDO11_RS06110	COG1376	ErfK ybiS ycfS ynhG family protein
CDO11_RS06135	COG1022	Amp-dependent synthetase and ligase
CDO11_RS06145	COG1028	Short-chain dehydrogenase reductase Sdr
CDO11_RS06160	COG0642	Histidine kinase
CDO11_RS06180	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CDO11_RS06185	COG4149	molybdate abc transporter
CDO11_RS06190	COG0725	ABC transporter, periplasmic molybdate-binding protein
CDO11_RS06195	COG3453	Protein conserved in bacteria
CDO11_RS06195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO11_RS06230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDO11_RS06255	COG0745	RESPONSE REGULATOR receiver
CDO11_RS06270	COG3039	Transposase
CDO11_RS06305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDO11_RS06310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDO11_RS06355	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CDO11_RS06420	COG2201	protein-glutamate methylesterase activity
CDO11_RS06455	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CDO11_RS06465	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CDO11_RS06470	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CDO11_RS06485	COG1842	Phage shock protein A
CDO11_RS06510	COG0754	glutathionylspermidine amidase activity
CDO11_RS06580	COG0531	amino acid
CDO11_RS06585	COG2197	response regulator
CDO11_RS06600	COG1113	amino acid transport
CDO11_RS06620	COG1271	oxidase subunit
CDO11_RS06625	COG1294	oxidase, subunit
CDO11_RS06645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDO11_RS06650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO11_RS06660	COG1660	Displays ATPase and GTPase activities
CDO11_RS06665	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CDO11_RS06670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO11_RS06685	COG1137	ATPase activity
CDO11_RS06690	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CDO11_RS06700	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CDO11_RS06710	COG0271	Belongs to the BolA IbaG family
CDO11_RS06720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDO11_RS06740	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDO11_RS06755	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDO11_RS06765	COG0628	permease
CDO11_RS06775	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDO11_RS06780	COG3178	'Phosphotransferase
CDO11_RS06795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDO11_RS06800	COG1555	photosystem II stabilization
CDO11_RS06850	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDO11_RS06860	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDO11_RS06885	COG0228	four-way junction DNA binding
CDO11_RS06890	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDO11_RS06895	COG0336	Belongs to the RNA methyltransferase TrmD family
CDO11_RS06910	COG0534	Mate efflux family protein
CDO11_RS06950	COG0542	response to heat
CDO11_RS06990	COG4206	TonB-dependent receptor
CDO11_RS07050	COG0019	diaminopimelate decarboxylase activity
CDO11_RS07065	COG4264	IucA IucC family
CDO11_RS07075	COG4772	TonB-dependent receptor
CDO11_RS07090	COG4651	solute:proton antiporter activity
CDO11_RS07090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDO11_RS07125	COG0488	(ABC) transporter
CDO11_RS07150	COG0657	acetylesterase activity
CDO11_RS07150	COG2755	lipolytic protein G-D-S-L family
CDO11_RS07170	COG2207	Transcriptional regulator
CDO11_RS07175	COG0326	Molecular chaperone. Has ATPase activity
CDO11_RS07205	COG3328	transposase activity
CDO11_RS07210	COG0174	glutamine synthetase
CDO11_RS07215	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CDO11_RS07225	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CDO11_RS07240	COG3039	Transposase
CDO11_RS07250	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDO11_RS07280	COG2146	nitrite reductase [NAD(P)H] activity
CDO11_RS07295	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDO11_RS07300	COG0719	Fe-S assembly protein
CDO11_RS07305	COG0396	ATPase activity
CDO11_RS07310	COG0719	Fe-S assembly protein
CDO11_RS07315	COG1959	2 iron, 2 sulfur cluster binding
CDO11_RS07335	COG0693	protein deglycase activity
CDO11_RS07380	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CDO11_RS07415	COG0519	Catalyzes the synthesis of GMP from XMP
CDO11_RS07425	COG1678	Uncharacterized ACR, COG1678
CDO11_RS07430	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDO11_RS07445	COG1764	response to oxidative stress
CDO11_RS07455	COG0384	phenazine biosynthesis protein PhzF
CDO11_RS07465	COG0527	aspartate kinase activity
CDO11_RS07495	COG0142	geranyltranstransferase activity
CDO11_RS07500	COG0629	single-stranded DNA binding
CDO11_RS07505	COG3706	GGDEF domain
CDO11_RS07505	COG2203	Gaf domain
CDO11_RS07505	COG4251	negative regulation of phosphorylation
CDO11_RS07505	COG5001	Diguanylate cyclase
CDO11_RS07540	COG2879	small protein
CDO11_RS07545	COG1966	Carbon starvation protein
CDO11_RS07550	COG1741	Belongs to the pirin family
CDO11_RS07665	COG1741	Belongs to the pirin family
CDO11_RS07675	COG1515	deoxyribonuclease V activity
CDO11_RS07695	COG3590	peptidase
CDO11_RS07710	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CDO11_RS07715	COG2200	EAL domain
CDO11_RS07715	COG2202	Pas domain
CDO11_RS07715	COG2199	diguanylate cyclase activity
CDO11_RS07720	COG0835	chemotaxis
CDO11_RS07725	COG0840	transmembrane signaling receptor activity
CDO11_RS07730	COG0643	Histidine kinase
CDO11_RS07730	COG2198	Histidine kinase
CDO11_RS07740	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDO11_RS07750	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CDO11_RS07770	COG2205	protein histidine kinase activity
CDO11_RS07795	COG3039	Transposase
CDO11_RS07820	COG3039	Transposase
CDO11_RS07825	COG3039	Transposase
CDO11_RS07860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDO11_RS07865	COG0735	belongs to the Fur family
CDO11_RS07925	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CDO11_RS07930	COG0084	hydrolase, TatD family'
CDO11_RS07945	COG1960	acyl-CoA dehydrogenase activity
CDO11_RS07960	COG0367	asparagine synthase
CDO11_RS07970	COG0305	Participates in initiation and elongation during chromosome replication
CDO11_RS07975	COG0415	Belongs to the DNA photolyase family
CDO11_RS07995	COG1028	Short-chain dehydrogenase reductase Sdr
CDO11_RS08040	COG3039	Transposase
CDO11_RS08130	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDO11_RS08140	COG0475	glutathione-regulated potassium exporter activity
CDO11_RS08240	COG5001	Diguanylate cyclase
CDO11_RS08240	COG5002	protein histidine kinase activity
CDO11_RS08245	COG1187	pseudouridine synthase activity
CDO11_RS08270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDO11_RS08280	COG0475	glutathione-regulated potassium exporter activity
CDO11_RS08285	COG5000	phosphorelay sensor kinase activity
CDO11_RS08285	COG5002	protein histidine kinase activity
CDO11_RS08290	COG0745	RESPONSE REGULATOR receiver
CDO11_RS08320	COG1132	(ABC) transporter
CDO11_RS08345	COG3039	Transposase
CDO11_RS08360	COG3039	Transposase
CDO11_RS08405	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CDO11_RS08415	COG4969	Belongs to the N-Me-Phe pilin family
CDO11_RS08420	COG2194	sulfuric ester hydrolase activity
CDO11_RS08460	COG0045	succinate-CoA ligase (ADP-forming) activity
CDO11_RS08465	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CDO11_RS08480	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDO11_RS08480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDO11_RS08485	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDO11_RS08490	COG0564	pseudouridine synthase activity
CDO11_RS08515	COG3387	PFAM Glycoside hydrolase 15-related
CDO11_RS08520	COG1877	trehalose-phosphatase activity
CDO11_RS08560	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CDO11_RS08580	COG1595	DNA-templated transcription, initiation
CDO11_RS08590	COG1946	Acyl-CoA thioesterase
CDO11_RS08605	COG0824	Thioesterase
CDO11_RS08610	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDO11_RS08620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDO11_RS08625	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDO11_RS08630	COG0268	Binds directly to 16S ribosomal RNA
CDO11_RS08635	COG0728	peptidoglycan biosynthetic process
CDO11_RS08640	COG0196	riboflavin kinase activity
CDO11_RS08650	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDO11_RS08655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDO11_RS08670	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO11_RS08675	COG1845	cytochrome c oxidase, subunit III
CDO11_RS08680	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CDO11_RS08700	COG3209	COG3209 Rhs family protein
CDO11_RS08855	COG0632	four-way junction helicase activity
CDO11_RS08865	COG2255	four-way junction helicase activity
CDO11_RS08870	COG0824	Thioesterase
CDO11_RS08880	COG0848	biopolymer transport protein
CDO11_RS08895	COG2885	chlorophyll binding
CDO11_RS08905	COG0602	queuosine metabolic process
CDO11_RS08915	COG1187	pseudouridine synthase activity
CDO11_RS08975	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CDO11_RS09000	COG0514	ATP-dependent DNA helicase (RecQ)
CDO11_RS09010	COG0783	Belongs to the Dps family
CDO11_RS09015	COG1643	Atp-dependent helicase
CDO11_RS09070	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDO11_RS09080	COG1215	transferase activity, transferring glycosyl groups
CDO11_RS09085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDO11_RS09095	COG1199	ATP-dependent helicase activity
CDO11_RS09105	COG1397	ADP-ribosylglycohydrolase
CDO11_RS09115	COG0189	ligase activity
CDO11_RS09130	COG0835	chemotaxis
CDO11_RS09135	COG0840	transmembrane signaling receptor activity
CDO11_RS09140	COG0643	Histidine kinase
CDO11_RS09140	COG0784	Response regulator, receiver
CDO11_RS09140	COG2198	Histidine kinase
CDO11_RS09185	COG1446	asparaginase
CDO11_RS09190	COG3142	Participates in the control of copper homeostasis
CDO11_RS09245	COG3537	Alpha-1,2-mannosidase
CDO11_RS09315	COG1472	Belongs to the glycosyl hydrolase 3 family
CDO11_RS09335	COG3858	chitin binding
CDO11_RS09335	COG1388	LysM domain
CDO11_RS09350	COG0837	glucose binding
CDO11_RS09355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDO11_RS09365	COG0494	nUDIX hydrolase
CDO11_RS09375	COG3956	TIGRFAM MazG family protein
CDO11_RS09390	COG0330	HflC and HflK could
CDO11_RS09405	COG0509	glycine decarboxylation via glycine cleavage system
CDO11_RS09440	COG1960	acyl-CoA dehydrogenase activity
CDO11_RS09450	COG1309	transcriptional regulator
CDO11_RS09455	COG4771	TonB-dependent receptor
CDO11_RS09465	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CDO11_RS09475	COG0463	Glycosyl transferase, family 2
CDO11_RS09495	COG1272	protein, Hemolysin III
CDO11_RS09505	COG0739	heme binding
CDO11_RS09510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDO11_RS09515	COG0626	cystathionine gamma-synthase activity
CDO11_RS09525	COG1760	l-serine dehydratase
CDO11_RS09540	COG2353	YceI-like domain
CDO11_RS09550	COG2353	YceI-like domain
CDO11_RS09605	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CDO11_RS09625	COG1960	acyl-CoA dehydrogenase activity
CDO11_RS09650	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO11_RS09650	COG1024	Enoyl-CoA hydratase
CDO11_RS09665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO11_RS09695	COG1381	Involved in DNA repair and RecF pathway recombination
CDO11_RS09710	COG2954	triphosphatase activity
CDO11_RS09715	COG2954	triphosphatase activity
CDO11_RS09730	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CDO11_RS09735	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
CDO11_RS09740	COG3046	protein related to deoxyribodipyrimidine photolyase
CDO11_RS09750	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CDO11_RS09755	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CDO11_RS09760	COG1278	Cold shock
CDO11_RS09780	COG1201	RNA secondary structure unwinding
CDO11_RS09785	COG1793	dna ligase
CDO11_RS09795	COG1793	dna ligase
CDO11_RS09795	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CDO11_RS09825	COG0183	Belongs to the thiolase family
CDO11_RS09850	COG1451	nucleotide metabolic process
CDO11_RS09865	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CDO11_RS09910	COG1047	Peptidyl-prolyl cis-trans
CDO11_RS09925	COG2824	Alkylphosphonate utilization operon protein PhnA
CDO11_RS09940	COG1902	pentaerythritol trinitrate reductase activity
CDO11_RS09945	COG2814	Major facilitator Superfamily
CDO11_RS10000	COG0392	lysyltransferase activity
CDO11_RS10000	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CDO11_RS10010	COG0251	oxidation-reduction process
CDO11_RS10015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDO11_RS10030	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDO11_RS10055	COG1595	DNA-templated transcription, initiation
CDO11_RS10075	COG2878	Part of a membrane complex involved in electron transport
CDO11_RS10085	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO11_RS10085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO11_RS10105	COG0833	amino acid
CDO11_RS10110	COG2040	homocysteine
CDO11_RS10125	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CDO11_RS10160	COG2895	sulfate adenylyltransferase (ATP) activity
CDO11_RS10160	COG0529	Catalyzes the synthesis of activated sulfate
CDO11_RS10205	COG1981	membrane
CDO11_RS10235	COG4771	TonB-dependent receptor
CDO11_RS10245	COG0825	malonyl-CoA metabolic process
CDO11_RS10265	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDO11_RS10270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDO11_RS10290	COG0750	zinc metalloprotease
CDO11_RS10300	COG0575	Belongs to the CDS family
CDO11_RS10310	COG0233	cytoplasmic translational termination
CDO11_RS10325	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDO11_RS10385	COG1393	Belongs to the ArsC family
CDO11_RS10400	COG0367	asparagine synthase
CDO11_RS10415	COG4774	siderophore transport
CDO11_RS10455	COG1566	PFAM secretion protein HlyD family protein
CDO11_RS10460	COG2814	Major facilitator Superfamily
CDO11_RS10505	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDO11_RS10515	COG1960	acyl-CoA dehydrogenase activity
CDO11_RS10540	COG2914	Belongs to the UPF0125 (RnfH) family
CDO11_RS10550	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDO11_RS10560	COG0497	DNA recombination
CDO11_RS10570	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CDO11_RS10575	COG0443	Heat shock 70 kDa protein
CDO11_RS10580	COG0484	heat shock protein binding
CDO11_RS10590	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CDO11_RS10595	COG1605	Chorismate mutase
CDO11_RS10595	COG0287	Prephenate dehydrogenase
CDO11_RS10615	COG0583	DNA-binding transcription factor activity
CDO11_RS10630	COG1132	(ABC) transporter
CDO11_RS10665	COG2850	peptidyl-arginine hydroxylation
CDO11_RS10745	COG1131	(ABC) transporter
CDO11_RS10750	COG1725	Transcriptional regulator
CDO11_RS10760	COG0386	Belongs to the glutathione peroxidase family
CDO11_RS10775	COG2900	Belongs to the SlyX family
CDO11_RS10790	COG1609	Transcriptional regulator
CDO11_RS10800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO11_RS10810	COG0646	methionine synthase
CDO11_RS10810	COG1410	methionine synthase
CDO11_RS10815	COG0646	methionine synthase
CDO11_RS10815	COG1410	methionine synthase
CDO11_RS10820	COG2226	methyltransferase
CDO11_RS10825	COG1960	acyl-CoA dehydrogenase activity
CDO11_RS10855	COG0557	exoribonuclease II activity
CDO11_RS10875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDO11_RS10895	COG3039	Transposase
CDO11_RS10920	COG3328	transposase activity
CDO11_RS10930	COG1278	Cold shock
CDO11_RS10945	COG3039	Transposase
CDO11_RS10955	COG3039	Transposase
CDO11_RS11015	COG3039	Transposase
CDO11_RS11065	COG3039	Transposase
CDO11_RS11075	COG0583	DNA-binding transcription factor activity
CDO11_RS11135	COG2201	protein-glutamate methylesterase activity
CDO11_RS11170	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CDO11_RS11180	COG0531	amino acid
CDO11_RS11185	COG0531	amino acid
CDO11_RS11195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDO11_RS11200	COG0277	FAD linked oxidase domain protein
CDO11_RS11265	COG0436	Aminotransferase
CDO11_RS11290	COG1187	pseudouridine synthase activity
CDO11_RS11295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDO11_RS11300	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDO11_RS11305	COG2350	Protein conserved in bacteria
CDO11_RS11335	COG1175	transmembrane transport
CDO11_RS11340	COG0395	ABC-type sugar transport system, permease component
CDO11_RS11360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDO11_RS11370	COG2957	Belongs to the agmatine deiminase family
CDO11_RS11385	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CDO11_RS11390	COG0539	negative regulation of cytoplasmic translation
CDO11_RS11395	COG0776	regulation of translation
CDO11_RS11405	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CDO11_RS11410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDO11_RS11420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDO11_RS11440	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDO11_RS11455	COG3002	Belongs to the UPF0753 family
CDO11_RS11460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDO11_RS11465	COG0583	DNA-binding transcription factor activity
CDO11_RS11495	COG0583	DNA-binding transcription factor activity
CDO11_RS11520	COG1914	H( )-stimulated, divalent metal cation uptake system
CDO11_RS11540	COG0668	transmembrane transport
CDO11_RS11595	COG1028	Short-chain dehydrogenase reductase Sdr
CDO11_RS11600	COG1183	phosphatidylcholine synthase activity
CDO11_RS11610	COG3243	poly(R)-hydroxyalkanoic acid synthase
CDO11_RS11625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO11_RS11625	COG0723	plastoquinol--plastocyanin reductase activity
CDO11_RS11635	COG2183	response to ionizing radiation
CDO11_RS11650	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CDO11_RS11665	COG0671	phosphoesterase, PA-phosphatase related
CDO11_RS11690	COG1794	racemase activity, acting on amino acids and derivatives
CDO11_RS11700	COG0697	spore germination
CDO11_RS11725	COG1012	belongs to the aldehyde dehydrogenase family
CDO11_RS11760	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CDO11_RS11775	COG0124	histidyl-tRNA synthetase
CDO11_RS11795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDO11_RS11810	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CDO11_RS11810	COG0131	Imidazoleglycerol-phosphate dehydratase
CDO11_RS11820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CDO11_RS11830	COG0140	phosphoribosyl-ATP diphosphatase activity
CDO11_RS11830	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDO11_RS11870	COG0653	protein targeting
CDO11_RS12020	COG3039	Transposase
CDO11_RS12105	COG2801	Transposase and inactivated derivatives
CDO11_RS12155	COG3328	transposase activity
CDO11_RS12190	COG0322	excinuclease ABC activity
CDO11_RS12200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDO11_RS12210	COG1663	tetraacyldisaccharide 4'-kinase activity
CDO11_RS12225	COG0811	peptide transport
CDO11_RS12255	COG4591	ABC-type transport system involved in lipoprotein release permease component
CDO11_RS12270	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CDO11_RS12285	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CDO11_RS12300	COG0354	folic acid binding
CDO11_RS12315	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CDO11_RS12325	COG0363	glucosamine-6-phosphate deaminase activity
CDO11_RS12330	COG0129	dihydroxy-acid dehydratase activity
CDO11_RS12335	COG0800	Aldolase
CDO11_RS12370	COG2205	protein histidine kinase activity
CDO11_RS12370	COG5002	protein histidine kinase activity
CDO11_RS12370	COG0784	Response regulator, receiver
CDO11_RS12450	COG0386	Belongs to the glutathione peroxidase family
CDO11_RS12540	COG4251	negative regulation of phosphorylation
CDO11_RS12540	COG5001	Diguanylate cyclase
CDO11_RS12540	COG3706	GGDEF domain
CDO11_RS12540	COG2203	Gaf domain
CDO11_RS12560	COG1472	Belongs to the glycosyl hydrolase 3 family
CDO11_RS12610	COG0617	tRNA 3'-terminal CCA addition
CDO11_RS12620	COG1469	GTP cyclohydrolase I activity
CDO11_RS12625	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDO11_RS12675	COG4566	intracellular signal transduction
CDO11_RS12715	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDO11_RS12720	COG0077	Prephenate dehydratase
CDO11_RS12720	COG1605	Chorismate mutase
CDO11_RS12730	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CDO11_RS12775	COG1228	amidohydrolase
CDO11_RS12780	COG2986	histidine ammonia-lyase
CDO11_RS12790	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CDO11_RS12815	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CDO11_RS12830	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CDO11_RS12845	COG3115	cell septum assembly
CDO11_RS12855	COG0359	binds to the 23S rRNA
CDO11_RS12865	COG0360	Binds together with S18 to 16S ribosomal RNA
CDO11_RS12870	COG0316	Belongs to the HesB IscA family
CDO11_RS12905	COG0288	reversible hydration of carbon dioxide
CDO11_RS12930	COG2925	Exonuclease
CDO11_RS12940	COG0667	Aldo Keto reductase
CDO11_RS12965	COG0116	Belongs to the methyltransferase superfamily
CDO11_RS12965	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CDO11_RS13010	COG0494	nUDIX hydrolase
CDO11_RS13020	COG1024	Enoyl-CoA hydratase
CDO11_RS13030	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDO11_RS13045	COG3039	Transposase
CDO11_RS13085	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDO11_RS13090	COG0573	inorganic phosphate transmembrane transporter activity
CDO11_RS13105	COG0704	Plays a role in the regulation of phosphate uptake
CDO11_RS13115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDO11_RS13130	COG3328	transposase activity
CDO11_RS13165	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CDO11_RS13170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CDO11_RS13175	COG1862	Preprotein translocase
CDO11_RS13180	COG0343	queuine tRNA-ribosyltransferase activity
CDO11_RS13265	COG0405	Gamma-glutamyltransferase
CDO11_RS13270	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDO11_RS13285	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CDO11_RS13290	COG0742	ribosomal rna small subunit methyltransferase
CDO11_RS13310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CDO11_RS13345	COG3039	Transposase
CDO11_RS13375	COG0303	'Molybdopterin
CDO11_RS13385	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDO11_RS13395	COG1426	Protein conserved in bacteria
CDO11_RS13405	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDO11_RS13420	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO11_RS13420	COG1024	Enoyl-CoA hydratase
CDO11_RS13425	COG0183	Belongs to the thiolase family
CDO11_RS13430	COG0038	chloride channel
CDO11_RS13450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDO11_RS13475	COG1674	ftsk spoiiie
CDO11_RS13480	COG0492	ferredoxin-NADP+ reductase activity
CDO11_RS13505	COG0542	response to heat
CDO11_RS13520	COG0482	sulfurtransferase activity
CDO11_RS13545	COG5001	Diguanylate cyclase
CDO11_RS13550	COG4585	Histidine kinase
CDO11_RS13560	COG5002	protein histidine kinase activity
CDO11_RS13580	COG0784	Response regulator, receiver
CDO11_RS13580	COG0835	chemotaxis
CDO11_RS13590	COG1558	bacterial-type flagellum-dependent cell motility
CDO11_RS13595	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CDO11_RS13605	COG4787	bacterial-type flagellum-dependent cell motility
CDO11_RS13645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDO11_RS13650	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CDO11_RS13680	COG2201	protein-glutamate methylesterase activity
CDO11_RS13700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDO11_RS13710	COG1028	Short-chain dehydrogenase reductase Sdr
CDO11_RS13745	COG1677	Flagellar hook-basal body complex protein FliE
CDO11_RS13795	COG3190	flagellar
CDO11_RS13815	COG1684	flagellar biosynthetic protein fliR
CDO11_RS13870	COG2198	Histidine kinase
CDO11_RS13870	COG0784	Response regulator, receiver
CDO11_RS13870	COG0643	Histidine kinase
CDO11_RS13910	COG3039	Transposase
CDO11_RS13925	COG3209	COG3209 Rhs family protein
CDO11_RS13935	COG3039	Transposase
CDO11_RS13945	COG3039	Transposase
CDO11_RS14035	COG3039	Transposase
CDO11_RS14050	COG4988	ABC transporter
CDO11_RS14065	COG3039	Transposase
CDO11_RS14100	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CDO11_RS14120	COG0165	Argininosuccinate lyase
CDO11_RS14135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDO11_RS14140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDO11_RS14150	COG0137	argininosuccinate synthase activity
CDO11_RS14155	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDO11_RS14170	COG2166	iron-sulfur cluster assembly
CDO11_RS14195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDO11_RS14235	COG3039	Transposase
CDO11_RS14250	COG4677	pectinesterase activity
CDO11_RS14280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDO11_RS14285	COG0402	S-adenosylhomocysteine deaminase activity
CDO11_RS14300	COG1509	lysine 2,3-aminomutase activity
CDO11_RS14305	COG3300	MHYT domain
CDO11_RS14305	COG5001	Diguanylate cyclase
CDO11_RS14320	COG0483	inositol monophosphate 1-phosphatase activity
CDO11_RS14325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDO11_RS14350	COG0488	(ABC) transporter
CDO11_RS14355	COG0513	Belongs to the DEAD box helicase family
CDO11_RS14375	COG0625	glutathione transferase activity
CDO11_RS14385	COG1671	Belongs to the UPF0178 family
CDO11_RS14390	COG4681	YaeQ
CDO11_RS14395	COG2081	HI0933 family
CDO11_RS14415	COG1028	Short-chain dehydrogenase reductase Sdr
CDO11_RS14440	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDO11_RS14445	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDO11_RS14450	COG0802	atpase or kinase
CDO11_RS14455	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDO11_RS14455	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDO11_RS14460	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDO11_RS14485	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDO11_RS14570	COG3328	transposase activity
CDO11_RS14615	COG2969	positive regulation of protein catabolic process
CDO11_RS14620	COG0625	glutathione transferase activity
CDO11_RS14625	COG2857	Cytochrome c1
CDO11_RS14630	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CDO11_RS14635	COG0723	plastoquinol--plastocyanin reductase activity
CDO11_RS14645	COG0741	lytic transglycosylase activity
CDO11_RS14670	COG1702	phosphate starvation-inducible protein PhoH
CDO11_RS14690	COG4535	Mg2 and Co2 transporter CorC
CDO11_RS14705	COG1012	belongs to the aldehyde dehydrogenase family
CDO11_RS14715	COG1177	transmembrane transport
CDO11_RS14720	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO11_RS14725	COG3842	ATPase activity
CDO11_RS14780	COG0477	Major facilitator Superfamily
CDO11_RS14790	COG0243	molybdopterin cofactor binding
CDO11_RS14800	COG2223	nitrite transmembrane transporter activity
CDO11_RS14810	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO11_RS14815	COG1121	(ABC) transporter
CDO11_RS14825	COG2733	membrane
CDO11_RS14830	COG5002	protein histidine kinase activity
CDO11_RS14830	COG2205	protein histidine kinase activity
CDO11_RS14830	COG0784	Response regulator, receiver
CDO11_RS14840	COG3039	Transposase
CDO11_RS14860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO11_RS14865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO11_RS14885	COG1609	Transcriptional regulator
CDO11_RS14890	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO11_RS14890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDO11_RS14895	COG1105	Belongs to the carbohydrate kinase PfkB family
CDO11_RS14900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDO11_RS14900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDO11_RS14915	COG3039	Transposase
CDO11_RS15065	COG3039	Transposase
CDO11_RS15095	COG4771	TonB-dependent receptor
CDO11_RS15105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDO11_RS15125	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CDO11_RS15130	COG1360	Flagellar Motor Protein
CDO11_RS15140	COG0835	chemotaxis
CDO11_RS15150	COG0745	RESPONSE REGULATOR receiver
CDO11_RS15175	COG0840	transmembrane signaling receptor activity
CDO11_RS15190	COG0840	transmembrane signaling receptor activity
CDO11_RS15200	COG0840	transmembrane signaling receptor activity
CDO11_RS15210	COG0840	transmembrane signaling receptor activity
CDO11_RS15215	COG0840	transmembrane signaling receptor activity
CDO11_RS15220	COG0840	transmembrane signaling receptor activity
CDO11_RS15225	COG0840	transmembrane signaling receptor activity
CDO11_RS15245	COG0835	chemotaxis
CDO11_RS15270	COG0840	transmembrane signaling receptor activity
CDO11_RS15305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDO11_RS15335	COG0318	PFAM AMP-dependent synthetase and ligase
CDO11_RS15340	COG1024	Enoyl-CoA hydratase
CDO11_RS15345	COG0784	Response regulator, receiver
CDO11_RS15345	COG2198	Histidine kinase
CDO11_RS15345	COG2205	protein histidine kinase activity
CDO11_RS15415	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDO11_RS15425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO11_RS15430	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDO11_RS15440	COG0505	Belongs to the CarA family
CDO11_RS15445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDO11_RS15455	COG2258	MOSC domain
CDO11_RS15460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO11_RS15510	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDO11_RS15530	COG0477	Major facilitator Superfamily
CDO11_RS15540	COG1070	Carbohydrate kinase
CDO11_RS15550	COG1501	Belongs to the glycosyl hydrolase 31 family
CDO11_RS15565	COG0800	Aldolase
CDO11_RS15570	COG4948	Mandelate Racemase Muconate Lactonizing
CDO11_RS15580	COG3734	2-keto-3-deoxy-galactonokinase
CDO11_RS15585	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CDO11_RS15595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO11_RS15610	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDO11_RS15615	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CDO11_RS15625	COG0351	phosphomethylpyrimidine kinase
CDO11_RS15655	COG0583	DNA-binding transcription factor activity
CDO11_RS15660	COG1741	Belongs to the pirin family
CDO11_RS15680	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDO11_RS15685	COG0305	Participates in initiation and elongation during chromosome replication
CDO11_RS15710	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CDO11_RS15715	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDO11_RS15720	COG2137	regulation of response to DNA damage stimulus
CDO11_RS15730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDO11_RS15745	COG1546	Belongs to the CinA family
CDO11_RS15750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDO11_RS15765	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDO11_RS15775	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CDO11_RS15780	COG1534	Rna-binding protein
CDO11_RS15795	COG1238	metal cluster binding
CDO11_RS15800	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO11_RS15805	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CDO11_RS15810	COG2840	Smr protein MutS2
CDO11_RS15820	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CDO11_RS15835	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CDO11_RS15840	COG0148	phosphopyruvate hydratase activity
CDO11_RS15850	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CDO11_RS15855	COG0504	CTP synthase activity
CDO11_RS15880	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CDO11_RS15885	COG0306	phosphate transporter
CDO11_RS15900	COG1253	flavin adenine dinucleotide binding
CDO11_RS15915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO11_RS15935	COG0477	Major facilitator Superfamily
CDO11_RS15945	COG1132	(ABC) transporter
CDO11_RS15950	COG1136	(ABC) transporter
CDO11_RS15970	COG0438	transferase activity, transferring glycosyl groups
CDO11_RS15980	COG2264	protein methyltransferase activity
CDO11_RS16010	COG2244	polysaccharide biosynthetic process
CDO11_RS16060	COG1595	DNA-templated transcription, initiation
CDO11_RS16075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDO11_RS16095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO11_RS16170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO11_RS16175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO11_RS16230	COG1858	cytochrome C peroxidase
CDO11_RS16265	COG0515	serine threonine protein kinase
CDO11_RS16270	COG0631	protein serine/threonine phosphatase activity
CDO11_RS16385	COG3039	Transposase
CDO11_RS16405	COG3039	Transposase
CDO11_RS16450	COG0316	Belongs to the HesB IscA family
CDO11_RS16450	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CDO11_RS16455	COG2154	pterin-4-alpha-carbinolamine dehydratase
CDO11_RS16465	COG0428	transporter
CDO11_RS16470	COG0428	transporter
CDO11_RS16485	COG1530	ribonuclease E activity
CDO11_RS16505	COG1054	Belongs to the UPF0176 family
CDO11_RS16510	COG3039	Transposase
CDO11_RS16530	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CDO11_RS16570	COG3039	Transposase
CDO11_RS16575	COG3039	Transposase
CDO11_RS16605	COG1648	precorrin-2 dehydrogenase activity
CDO11_RS16605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDO11_RS16630	COG0746	molybdenum cofactor guanylyltransferase activity
CDO11_RS16710	COG4206	TonB-dependent receptor
CDO11_RS16740	COG4206	TonB-dependent receptor
CDO11_RS16790	COG0531	amino acid
CDO11_RS16805	COG0006	proline dipeptidase activity
CDO11_RS16815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO11_RS16830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO11_RS16835	COG3938	Belongs to the proline racemase family
CDO11_RS16845	COG0552	protein localization to endoplasmic reticulum
CDO11_RS16870	COG0784	Response regulator, receiver
CDO11_RS16870	COG4191	Histidine kinase
CDO11_RS16960	COG3040	lipid binding
CDO11_RS17000	COG0438	transferase activity, transferring glycosyl groups
CDO11_RS17010	COG0438	transferase activity, transferring glycosyl groups
CDO11_RS17015	COG0438	transferase activity, transferring glycosyl groups
CDO11_RS17085	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CDO11_RS17125	COG4969	Belongs to the N-Me-Phe pilin family
CDO11_RS17165	COG1611	Belongs to the LOG family
CDO11_RS17180	COG2095	MarC family integral membrane protein
CDO11_RS17190	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CDO11_RS17225	COG1185	polyribonucleotide nucleotidyltransferase activity
CDO11_RS17230	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDO11_RS17250	COG0195	Participates in both transcription termination and antitermination
CDO11_RS17255	COG0779	Required for maturation of 30S ribosomal subunits
CDO11_RS17265	COG1007	ATP synthesis coupled electron transport
CDO11_RS17295	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CDO11_RS17300	COG1034	ATP synthesis coupled electron transport
CDO11_RS17305	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CDO11_RS17310	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CDO11_RS17315	COG0649	NAD binding
CDO11_RS17320	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDO11_RS17330	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDO11_RS17345	COG0149	triose-phosphate isomerase activity
CDO11_RS17395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDO11_RS17400	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CDO11_RS17425	COG0135	phosphoribosylanthranilate isomerase activity
CDO11_RS17430	COG0101	tRNA pseudouridine synthase activity
CDO11_RS17450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CDO11_RS17455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO11_RS17460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CDO11_RS17465	COG2890	protein-(glutamine-N5) methyltransferase activity
CDO11_RS17520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO11_RS17530	COG0412	Dienelactone hydrolase
CDO11_RS17550	COG0717	Belongs to the dCTP deaminase family
CDO11_RS17555	COG0489	protein tyrosine kinase activity
CDO11_RS17600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO11_RS17605	COG2311	Membrane
CDO11_RS17610	COG1047	Peptidyl-prolyl cis-trans
CDO11_RS17615	COG0791	NLP P60 protein
CDO11_RS17620	COG0791	NLP P60 protein
CDO11_RS17635	COG1301	dicarboxylic acid transport
CDO11_RS17640	COG1785	Belongs to the alkaline phosphatase family
CDO11_RS17645	COG0037	tRNA processing
CDO11_RS17650	COG1722	exodeoxyribonuclease VII activity
CDO11_RS17655	COG0142	geranyltranstransferase activity
CDO11_RS17680	COG0312	modulator of DNA gyrase
CDO11_RS17685	COG3028	Belongs to the UPF0307 family
CDO11_RS17690	COG0312	modulator of DNA gyrase
CDO11_RS17700	COG3164	Protein of unknown function
CDO11_RS17715	COG2968	Membrane
CDO11_RS17740	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CDO11_RS17765	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDO11_RS17795	COG3118	belongs to the thioredoxin family
CDO11_RS17885	COG3039	Transposase
CDO11_RS17890	COG3039	Transposase
CDO11_RS17985	COG2022	thiamine diphosphate biosynthetic process
CDO11_RS17995	COG0471	metal ion transport
CDO11_RS17995	COG3273	potassium ion transport
CDO11_RS18025	COG1970	mechanosensitive ion channel activity
CDO11_RS18050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDO11_RS18080	COG0308	aminopeptidase N
CDO11_RS18085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO11_RS18100	COG2895	sulfate adenylyltransferase (ATP) activity
CDO11_RS18100	COG0529	Catalyzes the synthesis of activated sulfate
CDO11_RS18105	COG0175	sulfate reduction
CDO11_RS18110	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDO11_RS18115	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDO11_RS18120	COG0175	sulfate reduction
CDO11_RS18140	COG2198	Histidine kinase
CDO11_RS18140	COG0784	Response regulator, receiver
CDO11_RS18140	COG2205	protein histidine kinase activity
CDO11_RS18190	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CDO11_RS18195	COG3588	fructose-bisphosphate aldolase
CDO11_RS18200	COG0469	pyruvate kinase activity
CDO11_RS18245	COG0753	catalase activity
CDO11_RS18270	COG3039	Transposase
CDO11_RS18290	COG1917	Cupin 2, conserved barrel domain protein
CDO11_RS18290	COG2207	Transcriptional regulator
CDO11_RS18320	COG1506	peptidase
CDO11_RS18320	COG0823	Involved in the tonB-independent uptake of proteins
CDO11_RS18345	COG3039	Transposase
CDO11_RS18350	COG1297	OPT oligopeptide transporter protein
CDO11_RS18455	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CDO11_RS18470	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
CDO11_RS18475	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
CDO11_RS18480	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CDO11_RS18500	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CDO11_RS18655	COG3179	chitinase
CDO11_RS18765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDO11_RS18820	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDO11_RS18830	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDO11_RS18920	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CDO11_RS18935	COG2197	response regulator
CDO11_RS18940	COG4585	Histidine kinase
CDO11_RS18960	COG2894	cell division
CDO11_RS18965	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CDO11_RS18975	COG0642	Histidine kinase
CDO11_RS18980	COG0745	RESPONSE REGULATOR receiver
CDO11_RS18985	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDO11_RS18995	COG2194	sulfuric ester hydrolase activity
CDO11_RS19025	COG3551	Protein conserved in bacteria
CDO11_RS19090	COG0203	ribosomal protein L17
CDO11_RS19100	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDO11_RS19105	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDO11_RS19115	COG0201	protein transport
CDO11_RS19125	COG1841	ribosomal large subunit assembly
CDO11_RS19155	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDO11_RS19165	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CDO11_RS19170	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDO11_RS19175	COG0255	Belongs to the universal ribosomal protein uL29 family
CDO11_RS19180	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CDO11_RS19190	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDO11_RS19205	COG0089	rRNA binding
CDO11_RS19210	COG0088	Forms part of the polypeptide exit tunnel
CDO11_RS19215	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDO11_RS19220	COG0051	transcription antitermination factor activity, RNA binding
CDO11_RS19240	COG0049	tRNA binding
CDO11_RS19245	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDO11_RS19250	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDO11_RS19255	COG0085	RNA polymerase activity
CDO11_RS19260	COG0222	ribosome binding
CDO11_RS19265	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDO11_RS19275	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDO11_RS19285	COG0250	Participates in transcription elongation, termination and antitermination
CDO11_RS19290	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CDO11_RS19320	COG0012	GTP binding
CDO11_RS19325	COG0193	aminoacyl-tRNA hydrolase activity
CDO11_RS19335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDO11_RS19350	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CDO11_RS19365	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDO11_RS19375	COG0521	Mo-molybdopterin cofactor biosynthetic process
CDO11_RS19395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO11_RS19400	COG1295	ribonuclease BN
CDO11_RS19430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDO11_RS19440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDO11_RS19470	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CDO11_RS19495	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CDO11_RS19510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDO11_RS19510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDO11_RS19560	COG2890	protein-(glutamine-N5) methyltransferase activity
CDO11_RS19570	COG3634	alkyl hydroperoxide reductase activity
CDO11_RS19575	COG0583	DNA-binding transcription factor activity
CDO11_RS19585	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO11_RS19665	COG4783	chaperone-mediated protein folding
CDO11_RS19680	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CDO11_RS19690	COG0438	transferase activity, transferring glycosyl groups
CDO11_RS19695	COG0671	phosphoesterase, PA-phosphatase related
CDO11_RS19700	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDO11_RS19720	COG2833	Protein of unknown function (DUF455)
CDO11_RS19740	COG0285	dihydrofolate synthase activity
CDO11_RS19750	COG0406	alpha-ribazole phosphatase activity
CDO11_RS19785	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDO11_RS19790	COG4208	sulfate ABC transporter
CDO11_RS19795	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CDO11_RS19800	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDO11_RS19805	COG0156	8-amino-7-oxononanoate synthase activity
CDO11_RS19835	COG0604	alcohol dehydrogenase
CDO11_RS19840	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDO11_RS19840	COG1902	pentaerythritol trinitrate reductase activity
CDO11_RS19980	COG3386	PFAM SMP-30 Gluconolaconase
CDO11_RS20000	COG1024	Enoyl-CoA hydratase
CDO11_RS20010	COG0318	PFAM AMP-dependent synthetase and ligase
CDO11_RS20015	COG0583	DNA-binding transcription factor activity
CDO11_RS20055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDO11_RS20060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDO11_RS20070	COG2096	Adenosyltransferase
CDO11_RS20075	COG0123	including yeast histone deacetylase and acetoin utilization protein
CDO11_RS20090	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDO11_RS20100	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDO11_RS20105	COG2967	ApaG domain
CDO11_RS20130	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CDO11_RS20150	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CDO11_RS20165	COG0642	Histidine kinase
CDO11_RS20180	COG4181	ATPase activity
CDO11_RS20190	COG2175	clavaminate synthase activity
CDO11_RS20200	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CDO11_RS20240	COG0667	Aldo Keto reductase
CDO11_RS20250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CDO11_RS20255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO11_RS20290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDO11_RS20345	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CDO11_RS20350	COG2226	methyltransferase
CDO11_RS20405	COG3321	synthase
CDO11_RS20405	COG1028	Short-chain dehydrogenase reductase Sdr
CDO11_RS20405	COG0604	alcohol dehydrogenase
CDO11_RS20420	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CDO11_RS20435	COG0494	nUDIX hydrolase
CDO11_RS20450	COG1388	LysM domain
CDO11_RS20450	COG4942	peptidase
CDO11_RS20460	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CDO11_RS20475	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CDO11_RS20480	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDO11_RS20485	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDO11_RS20500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDO11_RS20505	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDO11_RS20520	COG3116	cell division
CDO11_RS20525	COG0275	rRNA processing
CDO11_RS20560	COG0792	nuclease activity
CDO11_RS20565	COG1988	membrane-bound metal-dependent
CDO11_RS20570	COG0277	FAD linked oxidase domain protein
CDO11_RS20575	COG0745	RESPONSE REGULATOR receiver
CDO11_RS20580	COG2205	protein histidine kinase activity
CDO11_RS20590	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CDO11_RS20595	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CDO11_RS20620	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CDO11_RS20625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDO11_RS20630	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CDO11_RS20650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDO11_RS20650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDO11_RS20670	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDO11_RS20690	COG0488	(ABC) transporter
CDO11_RS20740	COG2205	protein histidine kinase activity
CDO11_RS20780	COG2205	protein histidine kinase activity
CDO11_RS20800	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CDO11_RS20835	COG3039	Transposase
CDO11_RS20840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDO11_RS20855	COG3039	Transposase
CDO11_RS20910	COG3039	Transposase
CDO11_RS20960	COG1649	PFAM Uncharacterised BCR, COG1649
CDO11_RS20960	COG0726	polysaccharide deacetylase
CDO11_RS20965	COG1215	transferase activity, transferring glycosyl groups
CDO11_RS20975	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CDO11_RS20980	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDO11_RS20985	COG1609	Transcriptional regulator
CDO11_RS20995	COG2188	Transcriptional regulator
CDO11_RS21010	COG3250	beta-galactosidase activity
CDO11_RS21065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CDO11_RS21070	COG4191	Histidine kinase
CDO11_RS21075	COG0784	Response regulator, receiver
CDO11_RS21080	COG4251	negative regulation of phosphorylation
CDO11_RS21085	COG2823	Periplasmic or secreted lipoprotein
CDO11_RS21090	COG0673	inositol 2-dehydrogenase activity
CDO11_RS21095	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CDO11_RS21130	COG1051	belongs to the nudix hydrolase family
CDO11_RS21130	COG1056	cytidyltransferase-related domain
CDO11_RS21165	COG2921	Belongs to the UPF0250 family
CDO11_RS21180	COG1686	Belongs to the peptidase S11 family
CDO11_RS21190	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CDO11_RS21195	COG2951	lytic endotransglycosylase activity
CDO11_RS21210	COG1388	LysM domain
CDO11_RS21210	COG5632	N-Acetylmuramoyl-L-alanine amidase
CDO11_RS21210	COG3409	Peptidoglycan-binding domain 1 protein
CDO11_RS21255	COG0772	Belongs to the SEDS family
CDO11_RS21270	COG1792	Involved in formation and maintenance of cell shape
CDO11_RS21275	COG1077	Cell shape determining protein MreB Mrl
CDO11_RS21280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO11_RS21285	COG3039	Transposase
CDO11_RS21335	COG2199	diguanylate cyclase activity
CDO11_RS21340	COG0308	aminopeptidase N
CDO11_RS21370	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CDO11_RS21400	COG0436	Aminotransferase
CDO11_RS21415	COG1505	serine-type exopeptidase activity
CDO11_RS21440	COG0181	hydroxymethylbilane synthase activity
CDO11_RS21450	COG3275	phosphorelay sensor kinase activity
CDO11_RS21495	COG0659	secondary active sulfate transmembrane transporter activity
CDO11_RS21500	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CDO11_RS21500	COG5297	Belongs to the glycosyl hydrolase family 6
CDO11_RS21575	COG0598	Magnesium transport protein CorA
CDO11_RS21585	COG1113	amino acid transport
CDO11_RS21595	COG5297	Belongs to the glycosyl hydrolase family 6
CDO11_RS21600	COG4305	rare lipoprotein A
CDO11_RS21605	COG0697	spore germination
CDO11_RS21665	COG4221	oxidoreductase activity
CDO11_RS21695	COG0456	acetyltransferase
CDO11_RS21705	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CDO11_RS21740	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDO11_RS21740	COG2111	Na H antiporter
CDO11_RS21745	COG1006	Multisubunit Na H antiporter MnhC subunit
CDO11_RS21750	COG0651	ATP synthesis coupled electron transport
CDO11_RS21760	COG2212	antiporter activity
CDO11_RS21765	COG1320	monovalent cation:proton antiporter activity
CDO11_RS21780	COG3039	Transposase
CDO11_RS21805	COG3104	oligopeptide transport
CDO11_RS21810	COG3483	tryptophan 2,3-dioxygenase activity
CDO11_RS21820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDO11_RS21855	COG0183	Belongs to the thiolase family
CDO11_RS21910	COG3039	Transposase
CDO11_RS21940	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CDO11_RS21945	COG3023	N-Acetylmuramoyl-L-alanine amidase
CDO11_RS21955	COG4948	Mandelate Racemase Muconate Lactonizing
CDO11_RS21995	COG0531	amino acid
CDO11_RS22030	COG4682	membrane
CDO11_RS22035	COG3039	Transposase
CDO11_RS22040	COG2133	pyrroloquinoline quinone binding
CDO11_RS22080	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDO11_RS22085	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDO11_RS22095	COG1610	YqeY-like protein
CDO11_RS22110	COG1295	ribonuclease BN
CDO11_RS22115	COG0358	DNA primase activity
CDO11_RS22180	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CDO11_RS22195	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDO11_RS22245	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDO11_RS22250	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDO11_RS22255	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CDO11_RS22265	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CDO11_RS22270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDO11_RS22285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDO11_RS22365	COG3039	Transposase
CDO11_RS22380	COG3328	transposase activity
CDO11_RS22395	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CDO11_RS22395	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CDO11_RS22405	COG1473	amidohydrolase
CDO11_RS22410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO11_RS22415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO11_RS22430	COG5383	Protein conserved in bacteria
CDO11_RS22470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDO11_RS22475	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CDO11_RS22490	COG0028	Belongs to the TPP enzyme family
CDO11_RS22495	COG4191	Histidine kinase
CDO11_RS22520	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDO11_RS22535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDO11_RS22540	COG3177	Filamentation induced by cAMP protein fic
CDO11_RS22555	COG0596	Alpha beta hydrolase
CDO11_RS22560	COG0727	PFAM Uncharacterised protein family (UPF0153)
CDO11_RS22565	COG0318	PFAM AMP-dependent synthetase and ligase
CDO11_RS22570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO11_RS22625	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDO11_RS22635	COG0129	dihydroxy-acid dehydratase activity
CDO11_RS22675	COG0408	coproporphyrinogen oxidase activity
CDO11_RS22730	COG3039	Transposase
CDO11_RS22790	COG2353	YceI-like domain
CDO11_RS22820	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CDO11_RS22835	COG3386	PFAM SMP-30 Gluconolaconase
CDO11_RS22875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDO11_RS22890	COG4771	TonB-dependent receptor
CDO11_RS22900	COG0459	protein refolding
CDO11_RS22925	COG1252	NADH dehydrogenase
CDO11_RS22935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDO11_RS22940	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDO11_RS22945	COG3437	response regulator, receiver
CDO11_RS22950	COG2177	Part of the ABC transporter FtsEX involved in
CDO11_RS22955	COG2884	Cell division ATP-binding protein ftsE
CDO11_RS22965	COG3118	belongs to the thioredoxin family
CDO11_RS22970	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CDO11_RS22985	COG0729	surface antigen
CDO11_RS22990	COG2911	Protein conserved in bacteria
CDO11_RS23025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDO11_RS23040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO11_RS23100	COG1733	regulation of RNA biosynthetic process
CDO11_RS23105	COG0702	epimerase
CDO11_RS23135	COG0583	DNA-binding transcription factor activity
CDO11_RS23140	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDO11_RS23160	COG0745	RESPONSE REGULATOR receiver
CDO11_RS23190	COG1902	pentaerythritol trinitrate reductase activity
CDO11_RS23195	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CDO11_RS23205	COG2814	Major facilitator Superfamily
CDO11_RS23210	COG0583	DNA-binding transcription factor activity
CDO11_RS23230	COG0084	hydrolase, TatD family'
CDO11_RS23280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDO11_RS23350	COG4770	biotin carboxylase activity
CDO11_RS23355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDO11_RS23360	COG1960	acyl-CoA dehydrogenase activity
CDO11_RS23415	COG0523	cobalamin synthesis protein
CDO11_RS23425	COG0697	spore germination
CDO11_RS23435	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CDO11_RS23455	COG0457	Tetratricopeptide repeat
CDO11_RS23470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDO11_RS23500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDO11_RS23500	COG0519	Catalyzes the synthesis of GMP from XMP
CDO11_RS23510	COG0805	protein transport
CDO11_RS23520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDO11_RS23530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CDO11_RS23585	COG3661	Belongs to the glycosyl hydrolase 67 family
CDO11_RS23595	COG4948	Mandelate Racemase Muconate Lactonizing
CDO11_RS23605	COG1472	Belongs to the glycosyl hydrolase 3 family
CDO11_RS23610	COG0246	Mannitol dehydrogenase
CDO11_RS23635	COG3693	PFAM glycoside hydrolase, family 10
CDO11_RS23660	COG2211	Major facilitator Superfamily
CDO11_RS23705	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CDO11_RS23755	COG1846	Transcriptional regulator
CDO11_RS23760	COG1764	response to oxidative stress
CDO11_RS23860	COG3549	Plasmid maintenance system killer
CDO11_RS23870	COG1074	ATP-dependent DNA helicase activity
CDO11_RS23875	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CDO11_RS23880	COG1196	nuclear chromosome segregation
CDO11_RS23920	COG2032	superoxide dismutase activity
CDO11_RS23925	COG2032	superoxide dismutase activity
CDO11_RS23930	COG2204	response regulator
CDO11_RS23935	COG3852	Histidine kinase
CDO11_RS23940	COG0004	ammonium transporteR
CDO11_RS23945	COG0347	Belongs to the P(II) protein family
CDO11_RS23950	COG0174	glutamine synthetase
CDO11_RS23955	COG1968	undecaprenyl-diphosphatase activity
CDO11_RS24000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDO11_RS24010	COG2062	phosphohistidine phosphatase, SixA
CDO11_RS24015	COG0489	protein tyrosine kinase activity
CDO11_RS24035	COG1396	sequence-specific DNA binding
CDO11_RS24040	COG3550	peptidyl-serine autophosphorylation
CDO11_RS24045	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CDO11_RS24050	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDO11_RS24065	COG0517	IMP dehydrogenase activity
CDO11_RS24065	COG1125	glycine betaine transport
CDO11_RS24080	COG1119	ATPase activity
CDO11_RS24090	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDO11_RS24105	COG3039	Transposase
CDO11_RS24130	COG0656	L-ascorbic acid biosynthetic process
CDO11_RS24135	COG2130	NADP-dependent
CDO11_RS24140	COG0667	Aldo Keto reductase
CDO11_RS24150	COG1187	pseudouridine synthase activity
CDO11_RS24165	COG1643	Atp-dependent helicase
CDO11_RS24170	COG4807	Protein conserved in bacteria
CDO11_RS24175	COG4948	Mandelate Racemase Muconate Lactonizing
CDO11_RS24185	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDO11_RS24210	COG3507	Belongs to the glycosyl hydrolase 43 family
CDO11_RS24255	COG3162	membrane
CDO11_RS24260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDO11_RS24275	COG0708	Exodeoxyribonuclease III
CDO11_RS24290	COG2091	lysine biosynthetic process via aminoadipic acid
CDO11_RS24300	COG3540	Alkaline phosphatase
CDO11_RS24330	COG2159	amidohydrolase
CDO11_RS24355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDO11_RS24360	COG0583	DNA-binding transcription factor activity
CDO11_RS24365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDO11_RS24385	COG0210	DNA helicase
CDO11_RS24400	COG0531	amino acid
CDO11_RS24410	COG1322	Protein conserved in bacteria
CDO11_RS24420	COG0386	Belongs to the glutathione peroxidase family
CDO11_RS24475	COG0793	Belongs to the peptidase S41A family
CDO11_RS24480	COG4942	peptidase
CDO11_RS24490	COG2234	aminopeptidase activity
CDO11_RS24540	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDO11_RS24545	COG0302	gtp cyclohydrolase
CDO11_RS24570	COG0477	Major facilitator Superfamily
CDO11_RS24670	COG1929	Belongs to the glycerate kinase type-1 family
CDO11_RS24675	COG2271	Major facilitator Superfamily
CDO11_RS24690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CDO11_RS24700	COG0861	Integral membrane protein TerC family
CDO11_RS24710	COG0584	glycerophosphoryl diester phosphodiesterase
CDO11_RS24720	COG0671	phosphoesterase, PA-phosphatase related
CDO11_RS24730	COG0726	polysaccharide deacetylase