locus-tag	class	description
BXU03_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BXU03_RS00030	COG0187	DNA topoisomerase II activity
BXU03_RS00040	COG0501	Belongs to the peptidase M48B family
BXU03_RS00070	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BXU03_RS00080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BXU03_RS00090	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BXU03_RS00100	COG4772	TonB-dependent receptor
BXU03_RS00115	COG3039	Transposase
BXU03_RS00120	COG1304	FMN binding
BXU03_RS00140	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BXU03_RS00150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXU03_RS00225	COG3039	Transposase
BXU03_RS00240	COG2826	transposase and inactivated derivatives, IS30 family
BXU03_RS00265	COG3039	Transposase
BXU03_RS00275	COG1090	epimerase
BXU03_RS00285	COG0642	Histidine kinase
BXU03_RS00295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BXU03_RS00405	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BXU03_RS00485	COG3264	Mechanosensitive ion channel
BXU03_RS00485	COG1511	domain protein
BXU03_RS00500	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BXU03_RS00510	COG2354	Protein conserved in bacteria
BXU03_RS00515	COG1649	PFAM Uncharacterised BCR, COG1649
BXU03_RS00535	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BXU03_RS00560	COG0702	epimerase
BXU03_RS00570	COG1858	cytochrome C peroxidase
BXU03_RS00655	COG0513	Belongs to the DEAD box helicase family
BXU03_RS00665	COG3039	Transposase
BXU03_RS00715	COG1136	(ABC) transporter
BXU03_RS00735	COG1136	(ABC) transporter
BXU03_RS00780	COG1272	protein, Hemolysin III
BXU03_RS00785	COG1205	dead DEAH box helicase
BXU03_RS00785	COG1111	helicase
BXU03_RS00850	COG0069	glutamate synthase activity
BXU03_RS00850	COG0067	glutamate synthase
BXU03_RS00850	COG0070	glutamate synthase
BXU03_RS00855	COG0493	'glutamate synthase
BXU03_RS00900	COG1609	Transcriptional regulator
BXU03_RS00935	COG0366	Alpha amylase catalytic
BXU03_RS00940	COG0366	Alpha amylase catalytic
BXU03_RS01000	COG0606	chelatase, subunit chli
BXU03_RS01045	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BXU03_RS01050	COG1166	arginine decarboxylase activity
BXU03_RS01115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BXU03_RS01140	COG1028	Short-chain dehydrogenase reductase Sdr
BXU03_RS01165	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BXU03_RS01185	COG0210	DNA helicase
BXU03_RS01200	COG3132	Protein of unknown function, DUF480
BXU03_RS01205	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BXU03_RS01210	COG0284	orotidine-5'-phosphate decarboxylase activity
BXU03_RS01245	COG2937	Belongs to the GPAT DAPAT family
BXU03_RS01275	COG2755	lipolytic protein G-D-S-L family
BXU03_RS01290	COG3186	Phenylalanine-4-hydroxylase
BXU03_RS01295	COG1522	sequence-specific DNA binding
BXU03_RS01345	COG1064	alcohol dehydrogenase
BXU03_RS01355	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BXU03_RS01365	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BXU03_RS01375	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BXU03_RS01395	COG0676	glucose-6-phosphate 1-epimerase activity
BXU03_RS01460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BXU03_RS01490	COG2853	Lipoprotein
BXU03_RS01505	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BXU03_RS01510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BXU03_RS01515	COG1127	ABC transporter
BXU03_RS01595	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXU03_RS01610	COG3039	Transposase
BXU03_RS01615	COG3265	gluconokinase activity
BXU03_RS01620	COG2211	Major facilitator Superfamily
BXU03_RS01625	COG3459	Glycosyltransferase 36 associated
BXU03_RS01640	COG2205	protein histidine kinase activity
BXU03_RS01650	COG1414	Transcriptional regulator
BXU03_RS01655	COG0738	Major facilitator superfamily
BXU03_RS01660	COG3254	rhamnose metabolic process
BXU03_RS01690	COG0339	signal peptide processing
BXU03_RS01720	COG0564	pseudouridine synthase activity
BXU03_RS01730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BXU03_RS01745	COG1181	Belongs to the D-alanine--D-alanine ligase family
BXU03_RS01830	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BXU03_RS01840	COG0842	Transport permease protein
BXU03_RS01845	COG1131	(ABC) transporter
BXU03_RS01870	COG1476	TRANSCRIPTIONal
BXU03_RS01880	COG4555	ABC transporter
BXU03_RS01915	COG0625	glutathione transferase activity
BXU03_RS01965	COG0583	DNA-binding transcription factor activity
BXU03_RS02000	COG1199	ATP-dependent helicase activity
BXU03_RS02020	COG1566	PFAM secretion protein HlyD family protein
BXU03_RS02050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BXU03_RS02090	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BXU03_RS02090	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BXU03_RS02095	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BXU03_RS02110	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BXU03_RS02150	COG3237	CsbD-like
BXU03_RS02155	COG0180	Tryptophanyl-tRNA synthetase
BXU03_RS02160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BXU03_RS02210	COG0753	catalase activity
BXU03_RS02225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BXU03_RS02235	COG0628	permease
BXU03_RS02250	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BXU03_RS02255	COG1040	competence protein
BXU03_RS02260	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BXU03_RS02265	COG0156	8-amino-7-oxononanoate synthase activity
BXU03_RS02280	COG1028	Short-chain dehydrogenase reductase Sdr
BXU03_RS02295	COG0463	Glycosyl transferase, family 2
BXU03_RS02305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BXU03_RS02310	COG3100	YcgL domain-containing protein
BXU03_RS02330	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BXU03_RS02350	COG2239	Acts as a magnesium transporter
BXU03_RS02360	COG1042	CoA-binding domain protein
BXU03_RS02360	COG0045	succinate-CoA ligase (ADP-forming) activity
BXU03_RS02360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BXU03_RS02375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BXU03_RS02385	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BXU03_RS02420	COG3485	protocatechuate 3,4-dioxygenase
BXU03_RS02440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXU03_RS02445	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BXU03_RS02470	COG4221	oxidoreductase activity
BXU03_RS02495	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BXU03_RS02520	COG0463	Glycosyl transferase, family 2
BXU03_RS02535	COG1475	DNA binding
BXU03_RS02540	COG1192	Involved in chromosome partitioning
BXU03_RS02555	COG0708	Exodeoxyribonuclease III
BXU03_RS02560	COG2211	Major facilitator Superfamily
BXU03_RS02575	COG0739	heme binding
BXU03_RS02620	COG0745	RESPONSE REGULATOR receiver
BXU03_RS02660	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BXU03_RS02685	COG2814	Major facilitator Superfamily
BXU03_RS02700	COG1289	transmembrane transporter activity
BXU03_RS02725	COG0151	Belongs to the GarS family
BXU03_RS02730	COG0138	bifunctional purine biosynthesis protein purh
BXU03_RS02740	COG2267	carboxylic ester hydrolase activity
BXU03_RS02750	COG2267	carboxylic ester hydrolase activity
BXU03_RS02755	COG0671	phosphoesterase, PA-phosphatase related
BXU03_RS02755	COG2453	phosphatase
BXU03_RS02770	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BXU03_RS02830	COG0439	Biotin carboxylase
BXU03_RS02840	COG0511	ligase activity, forming carbon-carbon bonds
BXU03_RS02845	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BXU03_RS02865	COG1324	tolerance protein
BXU03_RS02900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BXU03_RS02930	COG0534	Mate efflux family protein
BXU03_RS02935	COG0616	signal peptide processing
BXU03_RS02945	COG1028	Short-chain dehydrogenase reductase Sdr
BXU03_RS02960	COG0009	L-threonylcarbamoyladenylate synthase
BXU03_RS02965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BXU03_RS02965	COG1754	DNA topoisomerase type I activity
BXU03_RS02980	COG2922	Belongs to the Smg family
BXU03_RS02985	COG0758	DNA mediated transformation
BXU03_RS02990	COG1652	LysM domain
BXU03_RS02995	COG0242	peptide deformylase activity
BXU03_RS03000	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BXU03_RS03065	COG1560	Kdo2-lipid A biosynthetic process
BXU03_RS03075	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BXU03_RS03225	COG3039	Transposase
BXU03_RS03235	COG1271	oxidase subunit
BXU03_RS03300	COG2972	Histidine kinase
BXU03_RS03315	COG0531	amino acid
BXU03_RS03335	COG3590	peptidase
BXU03_RS03350	COG0667	Aldo Keto reductase
BXU03_RS03365	COG3384	dioxygenase
BXU03_RS03375	COG1573	uracil-dna glycosylase
BXU03_RS03385	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BXU03_RS03400	COG0025	NhaP-type Na H and K H
BXU03_RS03405	COG1131	(ABC) transporter
BXU03_RS03410	COG0842	Transport permease protein
BXU03_RS03425	COG1404	Belongs to the peptidase S8 family
BXU03_RS03440	COG0745	RESPONSE REGULATOR receiver
BXU03_RS03490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXU03_RS03515	COG2202	Pas domain
BXU03_RS03515	COG2205	protein histidine kinase activity
BXU03_RS03545	COG2813	Specifically methylates the guanine in position
BXU03_RS03550	COG1187	pseudouridine synthase activity
BXU03_RS03555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BXU03_RS03595	COG0697	spore germination
BXU03_RS03605	COG2011	ABC-type metal ion transport system permease component
BXU03_RS03635	COG0508	dehydrogenase complex catalyzes the overall conversion of
BXU03_RS03645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BXU03_RS03665	COG0356	it plays a direct role in the translocation of protons across the membrane
BXU03_RS03675	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BXU03_RS03685	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BXU03_RS03690	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BXU03_RS03695	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BXU03_RS03700	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BXU03_RS03755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXU03_RS03760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BXU03_RS03810	COG0339	signal peptide processing
BXU03_RS03850	COG1956	GAF domain-containing protein
BXU03_RS03855	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BXU03_RS03865	COG0720	synthase
BXU03_RS03875	COG0513	Belongs to the DEAD box helicase family
BXU03_RS03890	COG0625	glutathione transferase activity
BXU03_RS03920	COG0626	cystathionine gamma-synthase activity
BXU03_RS03970	COG3328	transposase activity
BXU03_RS03995	COG2086	electron transfer activity
BXU03_RS04020	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BXU03_RS04020	COG0662	Cupin 2, conserved barrel domain protein
BXU03_RS04025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BXU03_RS04065	COG3218	ABC-type transport auxiliary lipoprotein component
BXU03_RS04065	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BXU03_RS04070	COG1127	ABC transporter
BXU03_RS04075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BXU03_RS04095	COG0442	prolyl-tRNA aminoacylation
BXU03_RS04105	COG1183	phosphatidylcholine synthase activity
BXU03_RS04140	COG3039	Transposase
BXU03_RS04185	COG3039	Transposase
BXU03_RS04215	COG0525	valine-tRNA ligase activity
BXU03_RS04230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BXU03_RS04240	COG0795	lipopolysaccharide-transporting ATPase activity
BXU03_RS04255	COG4974	Belongs to the 'phage' integrase family
BXU03_RS04260	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BXU03_RS04265	COG0047	phosphoribosylformylglycinamidine synthase activity
BXU03_RS04265	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BXU03_RS04275	COG5295	Hep Hag repeat protein
BXU03_RS04285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BXU03_RS04295	COG1459	type II secretion system
BXU03_RS04300	COG2165	general secretion pathway protein
BXU03_RS04305	COG4970	Tfp pilus assembly protein FimT
BXU03_RS04310	COG2165	general secretion pathway protein
BXU03_RS04315	COG4795	General secretion pathway protein
BXU03_RS04320	COG3156	type II secretion system protein K
BXU03_RS04325	COG3166	PFAM Fimbrial assembly family protein
BXU03_RS04340	COG1450	Type ii and iii secretion system protein
BXU03_RS04355	COG2188	Transcriptional regulator
BXU03_RS04410	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BXU03_RS04415	COG1518	maintenance of DNA repeat elements
BXU03_RS04455	COG3039	Transposase
BXU03_RS04480	COG1399	metal-binding, possibly nucleic acid-binding protein
BXU03_RS04505	COG1028	Short-chain dehydrogenase reductase Sdr
BXU03_RS04510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BXU03_RS04520	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BXU03_RS04525	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BXU03_RS04550	COG3039	Transposase
BXU03_RS04560	COG3829	transcription factor binding
BXU03_RS04650	COG2826	transposase and inactivated derivatives, IS30 family
BXU03_RS04660	COG0678	peroxiredoxin activity
BXU03_RS04680	COG0330	HflC and HflK could
BXU03_RS04685	COG0330	HflC and HflK could
BXU03_RS04695	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BXU03_RS04700	COG0308	aminopeptidase N
BXU03_RS04765	COG1560	Kdo2-lipid A biosynthetic process
BXU03_RS04770	COG1519	Transferase
BXU03_RS04775	COG1538	Outer membrane efflux protein
BXU03_RS04780	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BXU03_RS04810	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BXU03_RS04815	COG0066	3-isopropylmalate dehydratase activity
BXU03_RS04850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BXU03_RS04860	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BXU03_RS04890	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BXU03_RS04910	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BXU03_RS04945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BXU03_RS04955	COG3781	membrane
BXU03_RS05105	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BXU03_RS05125	COG1217	gtp-binding protein TYPA
BXU03_RS05130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BXU03_RS05135	COG0039	L-malate dehydrogenase activity
BXU03_RS05140	COG0625	glutathione transferase activity
BXU03_RS05160	COG3039	Transposase
BXU03_RS05200	COG0584	glycerophosphoryl diester phosphodiesterase
BXU03_RS05235	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BXU03_RS05270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BXU03_RS05280	COG0583	DNA-binding transcription factor activity
BXU03_RS05285	COG3634	alkyl hydroperoxide reductase activity
BXU03_RS05295	COG2890	protein-(glutamine-N5) methyltransferase activity
BXU03_RS05335	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BXU03_RS05335	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BXU03_RS05350	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BXU03_RS05375	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BXU03_RS05405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BXU03_RS05415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BXU03_RS05445	COG1295	ribonuclease BN
BXU03_RS05450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BXU03_RS05470	COG0521	Mo-molybdopterin cofactor biosynthetic process
BXU03_RS05480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BXU03_RS05485	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BXU03_RS05495	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BXU03_RS05510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BXU03_RS05520	COG0193	aminoacyl-tRNA hydrolase activity
BXU03_RS05525	COG0012	GTP binding
BXU03_RS05555	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BXU03_RS05560	COG0250	Participates in transcription elongation, termination and antitermination
BXU03_RS05570	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BXU03_RS05580	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BXU03_RS05585	COG0222	ribosome binding
BXU03_RS05590	COG0085	RNA polymerase activity
BXU03_RS05595	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BXU03_RS05600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BXU03_RS05605	COG0049	tRNA binding
BXU03_RS05625	COG0051	transcription antitermination factor activity, RNA binding
BXU03_RS05630	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BXU03_RS05635	COG0088	Forms part of the polypeptide exit tunnel
BXU03_RS05640	COG0089	rRNA binding
BXU03_RS05655	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BXU03_RS05665	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BXU03_RS05670	COG0255	Belongs to the universal ribosomal protein uL29 family
BXU03_RS05675	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BXU03_RS05680	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BXU03_RS05690	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BXU03_RS05720	COG1841	ribosomal large subunit assembly
BXU03_RS05730	COG0201	protein transport
BXU03_RS05740	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BXU03_RS05745	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BXU03_RS05755	COG0203	ribosomal protein L17
BXU03_RS05820	COG3551	Protein conserved in bacteria
BXU03_RS05850	COG2194	sulfuric ester hydrolase activity
BXU03_RS05860	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BXU03_RS05865	COG0745	RESPONSE REGULATOR receiver
BXU03_RS05870	COG0642	Histidine kinase
BXU03_RS05880	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BXU03_RS05885	COG2894	cell division
BXU03_RS05905	COG4585	Histidine kinase
BXU03_RS05910	COG2197	response regulator
BXU03_RS05925	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BXU03_RS05950	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BXU03_RS05955	COG2963	transposase activity
BXU03_RS06055	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BXU03_RS06065	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BXU03_RS06080	COG3039	Transposase
BXU03_RS06130	COG3328	transposase activity
BXU03_RS06145	COG3179	chitinase
BXU03_RS06270	COG3039	Transposase
BXU03_RS06285	COG3039	Transposase
BXU03_RS06350	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BXU03_RS06370	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BXU03_RS06375	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BXU03_RS06380	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BXU03_RS06395	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BXU03_RS06480	COG0587	DNA-directed DNA polymerase activity
BXU03_RS06500	COG1297	OPT oligopeptide transporter protein
BXU03_RS06525	COG0823	Involved in the tonB-independent uptake of proteins
BXU03_RS06525	COG1506	peptidase
BXU03_RS06545	COG2207	Transcriptional regulator
BXU03_RS06545	COG1917	Cupin 2, conserved barrel domain protein
BXU03_RS06575	COG0753	catalase activity
BXU03_RS06620	COG0469	pyruvate kinase activity
BXU03_RS06630	COG3588	fructose-bisphosphate aldolase
BXU03_RS06635	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BXU03_RS06680	COG0784	Response regulator, receiver
BXU03_RS06680	COG2205	protein histidine kinase activity
BXU03_RS06680	COG2198	Histidine kinase
BXU03_RS06700	COG0175	sulfate reduction
BXU03_RS06705	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BXU03_RS06710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BXU03_RS06715	COG0175	sulfate reduction
BXU03_RS06720	COG2895	sulfate adenylyltransferase (ATP) activity
BXU03_RS06720	COG0529	Catalyzes the synthesis of activated sulfate
BXU03_RS06730	COG3039	Transposase
BXU03_RS06745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BXU03_RS06750	COG0308	aminopeptidase N
BXU03_RS06780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BXU03_RS06800	COG1970	mechanosensitive ion channel activity
BXU03_RS06830	COG0471	metal ion transport
BXU03_RS06830	COG3273	potassium ion transport
BXU03_RS06845	COG2022	thiamine diphosphate biosynthetic process
BXU03_RS06985	COG3118	belongs to the thioredoxin family
BXU03_RS07015	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BXU03_RS07040	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BXU03_RS07070	COG2968	Membrane
BXU03_RS07085	COG3164	Protein of unknown function
BXU03_RS07095	COG0312	modulator of DNA gyrase
BXU03_RS07100	COG3028	Belongs to the UPF0307 family
BXU03_RS07105	COG0312	modulator of DNA gyrase
BXU03_RS07130	COG0142	geranyltranstransferase activity
BXU03_RS07135	COG1722	exodeoxyribonuclease VII activity
BXU03_RS07140	COG0037	tRNA processing
BXU03_RS07145	COG1785	Belongs to the alkaline phosphatase family
BXU03_RS07150	COG1301	dicarboxylic acid transport
BXU03_RS07165	COG0791	NLP P60 protein
BXU03_RS07170	COG0791	NLP P60 protein
BXU03_RS07175	COG1047	Peptidyl-prolyl cis-trans
BXU03_RS07180	COG2311	Membrane
BXU03_RS07185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXU03_RS07230	COG0489	protein tyrosine kinase activity
BXU03_RS07235	COG0717	Belongs to the dCTP deaminase family
BXU03_RS07255	COG0412	Dienelactone hydrolase
BXU03_RS07265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BXU03_RS07320	COG2890	protein-(glutamine-N5) methyltransferase activity
BXU03_RS07325	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BXU03_RS07330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BXU03_RS07335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BXU03_RS07355	COG0101	tRNA pseudouridine synthase activity
BXU03_RS07360	COG0135	phosphoribosylanthranilate isomerase activity
BXU03_RS07370	COG0133	tryptophan synthase activity
BXU03_RS07385	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BXU03_RS07390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BXU03_RS07440	COG0149	triose-phosphate isomerase activity
BXU03_RS07455	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXU03_RS07465	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXU03_RS07470	COG0649	NAD binding
BXU03_RS07475	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BXU03_RS07480	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BXU03_RS07485	COG1034	ATP synthesis coupled electron transport
BXU03_RS07490	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BXU03_RS07520	COG1007	ATP synthesis coupled electron transport
BXU03_RS07530	COG0779	Required for maturation of 30S ribosomal subunits
BXU03_RS07535	COG0195	Participates in both transcription termination and antitermination
BXU03_RS07540	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BXU03_RS07555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BXU03_RS07560	COG1185	polyribonucleotide nucleotidyltransferase activity
BXU03_RS07595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BXU03_RS07605	COG2095	MarC family integral membrane protein
BXU03_RS07620	COG1611	Belongs to the LOG family
BXU03_RS07660	COG4969	Belongs to the N-Me-Phe pilin family
BXU03_RS07665	COG0556	nucleotide-excision repair
BXU03_RS07705	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BXU03_RS07720	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BXU03_RS07775	COG0438	transferase activity, transferring glycosyl groups
BXU03_RS07780	COG0438	transferase activity, transferring glycosyl groups
BXU03_RS07790	COG0438	transferase activity, transferring glycosyl groups
BXU03_RS07830	COG3040	lipid binding
BXU03_RS07915	COG4191	Histidine kinase
BXU03_RS07915	COG0784	Response regulator, receiver
BXU03_RS07940	COG0552	protein localization to endoplasmic reticulum
BXU03_RS07950	COG3938	Belongs to the proline racemase family
BXU03_RS07955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXU03_RS07970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BXU03_RS07980	COG0006	proline dipeptidase activity
BXU03_RS07995	COG0531	amino acid
BXU03_RS08045	COG4206	TonB-dependent receptor
BXU03_RS08075	COG3328	transposase activity
BXU03_RS08145	COG0746	molybdenum cofactor guanylyltransferase activity
BXU03_RS08170	COG1648	precorrin-2 dehydrogenase activity
BXU03_RS08170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BXU03_RS08200	COG3039	Transposase
BXU03_RS08205	COG3039	Transposase
BXU03_RS08235	COG3039	Transposase
BXU03_RS08250	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BXU03_RS08270	COG1054	Belongs to the UPF0176 family
BXU03_RS08290	COG1530	ribonuclease E activity
BXU03_RS08300	COG3064	Membrane
BXU03_RS08305	COG0428	transporter
BXU03_RS08310	COG0428	transporter
BXU03_RS08320	COG2154	pterin-4-alpha-carbinolamine dehydratase
BXU03_RS08325	COG0316	Belongs to the HesB IscA family
BXU03_RS08325	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BXU03_RS08375	COG3039	Transposase
BXU03_RS08505	COG0631	protein serine/threonine phosphatase activity
BXU03_RS08540	COG1858	cytochrome C peroxidase
BXU03_RS08605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXU03_RS08610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BXU03_RS08630	COG2201	protein-glutamate methylesterase activity
BXU03_RS08675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BXU03_RS08695	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BXU03_RS08710	COG1595	DNA-templated transcription, initiation
BXU03_RS08760	COG2244	polysaccharide biosynthetic process
BXU03_RS08790	COG2264	protein methyltransferase activity
BXU03_RS08800	COG0438	transferase activity, transferring glycosyl groups
BXU03_RS08815	COG1136	(ABC) transporter
BXU03_RS08820	COG1132	(ABC) transporter
BXU03_RS08830	COG0477	Major facilitator Superfamily
BXU03_RS08850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXU03_RS08865	COG1253	flavin adenine dinucleotide binding
BXU03_RS08880	COG0306	phosphate transporter
BXU03_RS08910	COG0504	CTP synthase activity
BXU03_RS08915	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BXU03_RS08925	COG0148	phosphopyruvate hydratase activity
BXU03_RS08930	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BXU03_RS08935	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BXU03_RS08945	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BXU03_RS08960	COG2840	Smr protein MutS2
BXU03_RS08965	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BXU03_RS08970	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BXU03_RS08975	COG1238	metal cluster binding
BXU03_RS08990	COG1534	Rna-binding protein
BXU03_RS08995	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BXU03_RS09005	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BXU03_RS09010	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BXU03_RS09020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BXU03_RS09025	COG1546	Belongs to the CinA family
BXU03_RS09040	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BXU03_RS09050	COG2137	regulation of response to DNA damage stimulus
BXU03_RS09055	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BXU03_RS09060	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BXU03_RS09080	COG0305	Participates in initiation and elongation during chromosome replication
BXU03_RS09085	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BXU03_RS09105	COG1741	Belongs to the pirin family
BXU03_RS09110	COG0583	DNA-binding transcription factor activity
BXU03_RS09140	COG0352	thiamine-phosphate diphosphorylase activity
BXU03_RS09140	COG0351	phosphomethylpyrimidine kinase
BXU03_RS09150	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BXU03_RS09155	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BXU03_RS09175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BXU03_RS09185	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BXU03_RS09190	COG3734	2-keto-3-deoxy-galactonokinase
BXU03_RS09200	COG4948	Mandelate Racemase Muconate Lactonizing
BXU03_RS09205	COG0800	Aldolase
BXU03_RS09220	COG1501	Belongs to the glycosyl hydrolase 31 family
BXU03_RS09230	COG1070	Carbohydrate kinase
BXU03_RS09240	COG0477	Major facilitator Superfamily
BXU03_RS09260	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BXU03_RS09310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXU03_RS09315	COG2258	MOSC domain
BXU03_RS09325	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BXU03_RS09330	COG0505	Belongs to the CarA family
BXU03_RS09340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BXU03_RS09345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BXU03_RS09355	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BXU03_RS09430	COG2198	Histidine kinase
BXU03_RS09430	COG2205	protein histidine kinase activity
BXU03_RS09430	COG0784	Response regulator, receiver
BXU03_RS09435	COG1024	Enoyl-CoA hydratase
BXU03_RS09440	COG0318	PFAM AMP-dependent synthetase and ligase
BXU03_RS09470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXU03_RS09505	COG0840	transmembrane signaling receptor activity
BXU03_RS09525	COG3039	Transposase
BXU03_RS09545	COG0835	chemotaxis
BXU03_RS09565	COG0840	transmembrane signaling receptor activity
BXU03_RS09570	COG0840	transmembrane signaling receptor activity
BXU03_RS09575	COG0840	transmembrane signaling receptor activity
BXU03_RS09580	COG0840	transmembrane signaling receptor activity
BXU03_RS09590	COG0840	transmembrane signaling receptor activity
BXU03_RS09600	COG0840	transmembrane signaling receptor activity
BXU03_RS09635	COG0745	RESPONSE REGULATOR receiver
BXU03_RS09645	COG0835	chemotaxis
BXU03_RS09655	COG1360	Flagellar Motor Protein
BXU03_RS09660	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BXU03_RS09680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BXU03_RS09690	COG4771	TonB-dependent receptor
BXU03_RS09740	COG3039	Transposase
BXU03_RS09890	COG3039	Transposase
BXU03_RS09920	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BXU03_RS09935	COG3039	Transposase
BXU03_RS09945	COG3039	Transposase
BXU03_RS09960	COG3039	Transposase
BXU03_RS09975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BXU03_RS09975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BXU03_RS09980	COG1105	Belongs to the carbohydrate kinase PfkB family
BXU03_RS09985	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BXU03_RS09985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BXU03_RS09990	COG1609	Transcriptional regulator
BXU03_RS10015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BXU03_RS10020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXU03_RS10030	COG2902	Dehydrogenase
BXU03_RS10040	COG3039	Transposase
BXU03_RS10050	COG2205	protein histidine kinase activity
BXU03_RS10050	COG0784	Response regulator, receiver
BXU03_RS10050	COG5002	protein histidine kinase activity
BXU03_RS10055	COG2733	membrane
BXU03_RS10065	COG1121	(ABC) transporter
BXU03_RS10070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BXU03_RS10080	COG2223	nitrite transmembrane transporter activity
BXU03_RS10090	COG0243	molybdopterin cofactor binding
BXU03_RS10100	COG0477	Major facilitator Superfamily
BXU03_RS10110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXU03_RS10115	COG0174	glutamine synthetase
BXU03_RS10160	COG3842	ATPase activity
BXU03_RS10170	COG1177	transmembrane transport
BXU03_RS10180	COG1012	belongs to the aldehyde dehydrogenase family
BXU03_RS10195	COG4535	Mg2 and Co2 transporter CorC
BXU03_RS10215	COG1702	phosphate starvation-inducible protein PhoH
BXU03_RS10240	COG0741	lytic transglycosylase activity
BXU03_RS10250	COG0723	plastoquinol--plastocyanin reductase activity
BXU03_RS10255	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BXU03_RS10260	COG2857	Cytochrome c1
BXU03_RS10265	COG0625	glutathione transferase activity
BXU03_RS10270	COG2969	positive regulation of protein catabolic process
BXU03_RS10315	COG3328	transposase activity
BXU03_RS10400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BXU03_RS10420	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BXU03_RS10425	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BXU03_RS10425	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BXU03_RS10430	COG0802	atpase or kinase
BXU03_RS10435	COG0860	N-Acetylmuramoyl-L-alanine amidase
BXU03_RS10440	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BXU03_RS10465	COG1028	Short-chain dehydrogenase reductase Sdr
BXU03_RS10475	COG0501	Belongs to the peptidase M48B family
BXU03_RS10485	COG2081	HI0933 family
BXU03_RS10490	COG4681	YaeQ
BXU03_RS10495	COG1671	Belongs to the UPF0178 family
BXU03_RS10505	COG0625	glutathione transferase activity
BXU03_RS10515	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BXU03_RS10520	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BXU03_RS10525	COG0513	Belongs to the DEAD box helicase family
BXU03_RS10530	COG0488	(ABC) transporter
BXU03_RS10555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BXU03_RS10560	COG0483	inositol monophosphate 1-phosphatase activity
BXU03_RS10575	COG3300	MHYT domain
BXU03_RS10575	COG5001	Diguanylate cyclase
BXU03_RS10580	COG1509	lysine 2,3-aminomutase activity
BXU03_RS10595	COG0402	S-adenosylhomocysteine deaminase activity
BXU03_RS10600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BXU03_RS10630	COG4677	pectinesterase activity
BXU03_RS10655	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BXU03_RS10680	COG2166	iron-sulfur cluster assembly
BXU03_RS10700	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BXU03_RS10705	COG0137	argininosuccinate synthase activity
BXU03_RS10715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BXU03_RS10720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BXU03_RS10735	COG0165	Argininosuccinate lyase
BXU03_RS10755	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BXU03_RS10790	COG3039	Transposase
BXU03_RS10805	COG4988	ABC transporter
BXU03_RS10810	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BXU03_RS10820	COG3039	Transposase
BXU03_RS10930	COG3209	COG3209 Rhs family protein
BXU03_RS10940	COG3039	Transposase
BXU03_RS10985	COG0643	Histidine kinase
BXU03_RS10985	COG2198	Histidine kinase
BXU03_RS10985	COG0784	Response regulator, receiver
BXU03_RS11045	COG1684	flagellar biosynthetic protein fliR
BXU03_RS11065	COG3190	flagellar
BXU03_RS11115	COG1677	Flagellar hook-basal body complex protein FliE
BXU03_RS11150	COG1028	Short-chain dehydrogenase reductase Sdr
BXU03_RS11160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BXU03_RS11180	COG2201	protein-glutamate methylesterase activity
BXU03_RS11210	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BXU03_RS11215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BXU03_RS11255	COG4787	bacterial-type flagellum-dependent cell motility
BXU03_RS11265	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BXU03_RS11270	COG1558	bacterial-type flagellum-dependent cell motility
BXU03_RS11280	COG0835	chemotaxis
BXU03_RS11280	COG0784	Response regulator, receiver
BXU03_RS11300	COG5002	protein histidine kinase activity
BXU03_RS11310	COG4585	Histidine kinase
BXU03_RS11315	COG5001	Diguanylate cyclase
BXU03_RS11340	COG0482	sulfurtransferase activity
BXU03_RS11355	COG0542	response to heat
BXU03_RS11380	COG0492	ferredoxin-NADP+ reductase activity
BXU03_RS11385	COG1674	ftsk spoiiie
BXU03_RS11410	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BXU03_RS11430	COG0038	chloride channel
BXU03_RS11435	COG0183	Belongs to the thiolase family
BXU03_RS11440	COG1024	Enoyl-CoA hydratase
BXU03_RS11440	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXU03_RS11455	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BXU03_RS11465	COG1426	Protein conserved in bacteria
BXU03_RS11475	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXU03_RS11485	COG0303	'Molybdopterin
BXU03_RS11540	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BXU03_RS11600	COG0742	ribosomal rna small subunit methyltransferase
BXU03_RS11605	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BXU03_RS11620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BXU03_RS11625	COG0405	Gamma-glutamyltransferase
BXU03_RS11735	COG0343	queuine tRNA-ribosyltransferase activity
BXU03_RS11740	COG1862	Preprotein translocase
BXU03_RS11745	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BXU03_RS11750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BXU03_RS11790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BXU03_RS11800	COG0704	Plays a role in the regulation of phosphate uptake
BXU03_RS11815	COG0573	inorganic phosphate transmembrane transporter activity
BXU03_RS11820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BXU03_RS11865	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BXU03_RS11875	COG1024	Enoyl-CoA hydratase
BXU03_RS11885	COG0494	nUDIX hydrolase
BXU03_RS11930	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BXU03_RS11930	COG0116	Belongs to the methyltransferase superfamily
BXU03_RS11955	COG0667	Aldo Keto reductase
BXU03_RS11965	COG2925	Exonuclease
BXU03_RS11995	COG0288	reversible hydration of carbon dioxide
BXU03_RS12030	COG0316	Belongs to the HesB IscA family
BXU03_RS12035	COG0360	Binds together with S18 to 16S ribosomal RNA
BXU03_RS12045	COG0359	binds to the 23S rRNA
BXU03_RS12055	COG3115	cell septum assembly
BXU03_RS12070	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BXU03_RS12090	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BXU03_RS12115	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BXU03_RS12125	COG2986	histidine ammonia-lyase
BXU03_RS12130	COG1228	amidohydrolase
BXU03_RS12175	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BXU03_RS12185	COG1605	Chorismate mutase
BXU03_RS12185	COG0077	Prephenate dehydratase
BXU03_RS12190	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BXU03_RS12220	COG4566	intracellular signal transduction
BXU03_RS12270	COG0860	N-Acetylmuramoyl-L-alanine amidase
BXU03_RS12275	COG1469	GTP cyclohydrolase I activity
BXU03_RS12285	COG0617	tRNA 3'-terminal CCA addition
BXU03_RS12295	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BXU03_RS12300	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BXU03_RS12335	COG1472	Belongs to the glycosyl hydrolase 3 family
BXU03_RS12355	COG3706	GGDEF domain
BXU03_RS12355	COG2203	Gaf domain
BXU03_RS12355	COG5001	Diguanylate cyclase
BXU03_RS12355	COG4251	negative regulation of phosphorylation
BXU03_RS12415	COG1595	DNA-templated transcription, initiation
BXU03_RS12445	COG0386	Belongs to the glutathione peroxidase family
BXU03_RS12530	COG3039	Transposase
BXU03_RS12545	COG5002	protein histidine kinase activity
BXU03_RS12545	COG0784	Response regulator, receiver
BXU03_RS12545	COG2205	protein histidine kinase activity
BXU03_RS12580	COG0800	Aldolase
BXU03_RS12585	COG0129	dihydroxy-acid dehydratase activity
BXU03_RS12590	COG0363	glucosamine-6-phosphate deaminase activity
BXU03_RS12600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BXU03_RS12615	COG0354	folic acid binding
BXU03_RS12630	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BXU03_RS12645	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BXU03_RS12660	COG4591	ABC-type transport system involved in lipoprotein release permease component
BXU03_RS12690	COG0811	peptide transport
BXU03_RS12705	COG1663	tetraacyldisaccharide 4'-kinase activity
BXU03_RS12715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BXU03_RS12725	COG0322	excinuclease ABC activity
BXU03_RS12760	COG3328	transposase activity
BXU03_RS12785	COG3039	Transposase
BXU03_RS12795	COG2801	Transposase and inactivated derivatives
BXU03_RS12805	COG2201	protein-glutamate methylesterase activity
BXU03_RS12850	COG0653	protein targeting
BXU03_RS12945	COG0140	phosphoribosyl-ATP diphosphatase activity
BXU03_RS12945	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BXU03_RS12955	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BXU03_RS12965	COG0131	Imidazoleglycerol-phosphate dehydratase
BXU03_RS12965	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BXU03_RS12980	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BXU03_RS13000	COG0124	histidyl-tRNA synthetase
BXU03_RS13015	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BXU03_RS13050	COG1012	belongs to the aldehyde dehydrogenase family
BXU03_RS13075	COG0697	spore germination
BXU03_RS13085	COG1794	racemase activity, acting on amino acids and derivatives
BXU03_RS13110	COG0671	phosphoesterase, PA-phosphatase related
BXU03_RS13125	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BXU03_RS13140	COG2183	response to ionizing radiation
BXU03_RS13150	COG0723	plastoquinol--plastocyanin reductase activity
BXU03_RS13150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXU03_RS13165	COG3243	poly(R)-hydroxyalkanoic acid synthase
BXU03_RS13175	COG1183	phosphatidylcholine synthase activity
BXU03_RS13180	COG1028	Short-chain dehydrogenase reductase Sdr
BXU03_RS13205	COG0668	transmembrane transport
BXU03_RS13225	COG1914	H( )-stimulated, divalent metal cation uptake system
BXU03_RS13285	COG0583	DNA-binding transcription factor activity
BXU03_RS13290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BXU03_RS13295	COG3002	Belongs to the UPF0753 family
BXU03_RS13310	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BXU03_RS13330	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BXU03_RS13340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BXU03_RS13345	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BXU03_RS13355	COG0776	regulation of translation
BXU03_RS13360	COG0539	negative regulation of cytoplasmic translation
BXU03_RS13365	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BXU03_RS13380	COG2957	Belongs to the agmatine deiminase family
BXU03_RS13390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BXU03_RS13415	COG0395	ABC-type sugar transport system, permease component
BXU03_RS13420	COG1175	transmembrane transport
BXU03_RS13450	COG2350	Protein conserved in bacteria
BXU03_RS13455	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BXU03_RS13460	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BXU03_RS13465	COG1187	pseudouridine synthase activity
BXU03_RS13490	COG0436	Aminotransferase
BXU03_RS13555	COG0277	FAD linked oxidase domain protein
BXU03_RS13560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BXU03_RS13570	COG0531	amino acid
BXU03_RS13575	COG0531	amino acid
BXU03_RS13580	COG0235	Class ii aldolase
BXU03_RS13585	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BXU03_RS13620	COG2201	protein-glutamate methylesterase activity
BXU03_RS13680	COG0583	DNA-binding transcription factor activity
BXU03_RS13690	COG3039	Transposase
BXU03_RS13805	COG3039	Transposase
BXU03_RS13820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BXU03_RS13840	COG0557	exoribonuclease II activity
BXU03_RS13870	COG1960	acyl-CoA dehydrogenase activity
BXU03_RS13875	COG2226	methyltransferase
BXU03_RS13880	COG0646	methionine synthase
BXU03_RS13880	COG1410	methionine synthase
BXU03_RS13885	COG0646	methionine synthase
BXU03_RS13885	COG1410	methionine synthase
BXU03_RS13895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXU03_RS13905	COG1609	Transcriptional regulator
BXU03_RS13920	COG2900	Belongs to the SlyX family
BXU03_RS13935	COG0386	Belongs to the glutathione peroxidase family
BXU03_RS13945	COG1725	Transcriptional regulator
BXU03_RS13950	COG1131	(ABC) transporter
BXU03_RS14015	COG2850	peptidyl-arginine hydroxylation
BXU03_RS14050	COG1132	(ABC) transporter
BXU03_RS14065	COG0583	DNA-binding transcription factor activity
BXU03_RS14085	COG1605	Chorismate mutase
BXU03_RS14085	COG0287	Prephenate dehydrogenase
BXU03_RS14090	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BXU03_RS14100	COG0484	heat shock protein binding
BXU03_RS14110	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BXU03_RS14120	COG0497	DNA recombination
BXU03_RS14130	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXU03_RS14140	COG2914	Belongs to the UPF0125 (RnfH) family
BXU03_RS14150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BXU03_RS14165	COG1960	acyl-CoA dehydrogenase activity
BXU03_RS14175	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BXU03_RS14230	COG2814	Major facilitator Superfamily
BXU03_RS14235	COG1566	PFAM secretion protein HlyD family protein
BXU03_RS14250	COG2207	Transcriptional regulator
BXU03_RS14285	COG4774	siderophore transport
BXU03_RS14300	COG0367	asparagine synthase
BXU03_RS14305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BXU03_RS14315	COG1393	Belongs to the ArsC family
BXU03_RS14375	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BXU03_RS14390	COG0233	cytoplasmic translational termination
BXU03_RS14400	COG0575	Belongs to the CDS family
BXU03_RS14410	COG0750	zinc metalloprotease
BXU03_RS14435	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BXU03_RS14440	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BXU03_RS14460	COG0825	malonyl-CoA metabolic process
BXU03_RS14470	COG4771	TonB-dependent receptor
BXU03_RS14475	COG1131	(ABC) transporter
BXU03_RS14495	COG1981	membrane
BXU03_RS14540	COG2895	sulfate adenylyltransferase (ATP) activity
BXU03_RS14540	COG0529	Catalyzes the synthesis of activated sulfate
BXU03_RS14575	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BXU03_RS14590	COG2040	homocysteine
BXU03_RS14595	COG0833	amino acid
BXU03_RS14615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BXU03_RS14615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BXU03_RS14625	COG2878	Part of a membrane complex involved in electron transport
BXU03_RS14645	COG1595	DNA-templated transcription, initiation
BXU03_RS14670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BXU03_RS14685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BXU03_RS14690	COG0251	oxidation-reduction process
BXU03_RS14700	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BXU03_RS14700	COG0392	lysyltransferase activity
BXU03_RS14730	COG3039	Transposase
BXU03_RS14755	COG2814	Major facilitator Superfamily
BXU03_RS14760	COG1902	pentaerythritol trinitrate reductase activity
BXU03_RS14775	COG2824	Alkylphosphonate utilization operon protein PhnA
BXU03_RS14790	COG1047	Peptidyl-prolyl cis-trans
BXU03_RS14840	COG3039	Transposase
BXU03_RS14845	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BXU03_RS14860	COG1451	nucleotide metabolic process
BXU03_RS14885	COG0183	Belongs to the thiolase family
BXU03_RS14915	COG1793	dna ligase
BXU03_RS14915	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BXU03_RS14925	COG1793	dna ligase
BXU03_RS14930	COG1201	RNA secondary structure unwinding
BXU03_RS14950	COG1278	Cold shock
BXU03_RS14955	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BXU03_RS14960	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BXU03_RS14970	COG3046	protein related to deoxyribodipyrimidine photolyase
BXU03_RS14980	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BXU03_RS15015	COG3039	Transposase
BXU03_RS15025	COG2954	triphosphatase activity
BXU03_RS15040	COG1381	Involved in DNA repair and RecF pathway recombination
BXU03_RS15070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BXU03_RS15085	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXU03_RS15085	COG1024	Enoyl-CoA hydratase
BXU03_RS15105	COG1024	Enoyl-CoA hydratase
BXU03_RS15110	COG1960	acyl-CoA dehydrogenase activity
BXU03_RS15180	COG2353	YceI-like domain
BXU03_RS15190	COG2353	YceI-like domain
BXU03_RS15205	COG1760	l-serine dehydratase
BXU03_RS15215	COG0626	cystathionine gamma-synthase activity
BXU03_RS15220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXU03_RS15225	COG0739	heme binding
BXU03_RS15235	COG1272	protein, Hemolysin III
BXU03_RS15255	COG0463	Glycosyl transferase, family 2
BXU03_RS15265	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BXU03_RS15275	COG4771	TonB-dependent receptor
BXU03_RS15280	COG1309	transcriptional regulator
BXU03_RS15290	COG1960	acyl-CoA dehydrogenase activity
BXU03_RS15325	COG0509	glycine decarboxylation via glycine cleavage system
BXU03_RS15340	COG0330	HflC and HflK could
BXU03_RS15355	COG3956	TIGRFAM MazG family protein
BXU03_RS15365	COG0494	nUDIX hydrolase
BXU03_RS15375	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BXU03_RS15380	COG0837	glucose binding
BXU03_RS15395	COG1388	LysM domain
BXU03_RS15395	COG3858	chitin binding
BXU03_RS15415	COG1472	Belongs to the glycosyl hydrolase 3 family
BXU03_RS15450	COG3537	Alpha-1,2-mannosidase
BXU03_RS15500	COG3142	Participates in the control of copper homeostasis
BXU03_RS15505	COG1446	asparaginase
BXU03_RS15540	COG3039	Transposase
BXU03_RS15565	COG2198	Histidine kinase
BXU03_RS15565	COG0784	Response regulator, receiver
BXU03_RS15565	COG0643	Histidine kinase
BXU03_RS15570	COG0840	transmembrane signaling receptor activity
BXU03_RS15575	COG0835	chemotaxis
BXU03_RS15590	COG0189	ligase activity
BXU03_RS15600	COG1397	ADP-ribosylglycohydrolase
BXU03_RS15610	COG1199	ATP-dependent helicase activity
BXU03_RS15620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BXU03_RS15625	COG1215	transferase activity, transferring glycosyl groups
BXU03_RS15635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BXU03_RS15650	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BXU03_RS15655	COG0535	radical SAM domain protein
BXU03_RS15660	COG0535	radical SAM domain protein
BXU03_RS15685	COG1643	Atp-dependent helicase
BXU03_RS15690	COG0783	Belongs to the Dps family
BXU03_RS15700	COG0514	ATP-dependent DNA helicase (RecQ)
BXU03_RS15725	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BXU03_RS15785	COG1187	pseudouridine synthase activity
BXU03_RS15795	COG0602	queuosine metabolic process
BXU03_RS15805	COG2885	chlorophyll binding
BXU03_RS15820	COG0848	biopolymer transport protein
BXU03_RS15830	COG0824	Thioesterase
BXU03_RS15835	COG2255	four-way junction helicase activity
BXU03_RS15845	COG0632	four-way junction helicase activity
BXU03_RS15990	COG3209	COG3209 Rhs family protein
BXU03_RS16015	COG3209	COG3209 Rhs family protein
BXU03_RS16015	COG3209	COG3209 Rhs family protein
BXU03_RS16035	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BXU03_RS16040	COG1845	cytochrome c oxidase, subunit III
BXU03_RS16045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BXU03_RS16060	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BXU03_RS16065	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BXU03_RS16075	COG0196	riboflavin kinase activity
BXU03_RS16080	COG0728	peptidoglycan biosynthetic process
BXU03_RS16085	COG0268	Binds directly to 16S ribosomal RNA
BXU03_RS16090	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BXU03_RS16095	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BXU03_RS16105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BXU03_RS16110	COG0824	Thioesterase
BXU03_RS16125	COG1946	Acyl-CoA thioesterase
BXU03_RS16135	COG1595	DNA-templated transcription, initiation
BXU03_RS16150	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BXU03_RS16190	COG1877	trehalose-phosphatase activity
BXU03_RS16195	COG3387	PFAM Glycoside hydrolase 15-related
BXU03_RS16220	COG0564	pseudouridine synthase activity
BXU03_RS16225	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXU03_RS16230	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BXU03_RS16230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BXU03_RS16240	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BXU03_RS16245	COG0045	succinate-CoA ligase (ADP-forming) activity
BXU03_RS16285	COG2194	sulfuric ester hydrolase activity
BXU03_RS16290	COG4969	Belongs to the N-Me-Phe pilin family
BXU03_RS16300	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BXU03_RS16340	COG3039	Transposase
BXU03_RS16400	COG1132	(ABC) transporter
BXU03_RS16430	COG0745	RESPONSE REGULATOR receiver
BXU03_RS16435	COG5002	protein histidine kinase activity
BXU03_RS16435	COG5000	phosphorelay sensor kinase activity
BXU03_RS16440	COG0475	glutathione-regulated potassium exporter activity
BXU03_RS16450	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BXU03_RS16475	COG1187	pseudouridine synthase activity
BXU03_RS16480	COG5001	Diguanylate cyclase
BXU03_RS16480	COG5002	protein histidine kinase activity
BXU03_RS16580	COG1028	Short-chain dehydrogenase reductase Sdr
BXU03_RS16600	COG0415	Belongs to the DNA photolyase family
BXU03_RS16605	COG0305	Participates in initiation and elongation during chromosome replication
BXU03_RS16615	COG0367	asparagine synthase
BXU03_RS16630	COG1960	acyl-CoA dehydrogenase activity
BXU03_RS16645	COG0084	hydrolase, TatD family'
BXU03_RS16650	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BXU03_RS16710	COG0735	belongs to the Fur family
BXU03_RS16715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BXU03_RS16735	COG3039	Transposase
BXU03_RS16750	COG3039	Transposase
BXU03_RS16755	COG3039	Transposase
BXU03_RS16810	COG2205	protein histidine kinase activity
BXU03_RS16830	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BXU03_RS16840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BXU03_RS16850	COG2198	Histidine kinase
BXU03_RS16850	COG0643	Histidine kinase
BXU03_RS16860	COG0840	transmembrane signaling receptor activity
BXU03_RS16865	COG0835	chemotaxis
BXU03_RS16870	COG2202	Pas domain
BXU03_RS16870	COG2200	EAL domain
BXU03_RS16870	COG2199	diguanylate cyclase activity
BXU03_RS16875	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BXU03_RS16890	COG3590	peptidase
BXU03_RS16910	COG0588	phosphoglycerate mutase activity
BXU03_RS16915	COG1515	deoxyribonuclease V activity
BXU03_RS16925	COG1741	Belongs to the pirin family
BXU03_RS16995	COG1741	Belongs to the pirin family
BXU03_RS17000	COG1966	Carbon starvation protein
BXU03_RS17005	COG2879	small protein
BXU03_RS17050	COG2203	Gaf domain
BXU03_RS17050	COG3706	GGDEF domain
BXU03_RS17050	COG4251	negative regulation of phosphorylation
BXU03_RS17050	COG5001	Diguanylate cyclase
BXU03_RS17060	COG0629	single-stranded DNA binding
BXU03_RS17065	COG0142	geranyltranstransferase activity
BXU03_RS17095	COG0527	aspartate kinase activity
BXU03_RS17105	COG0384	phenazine biosynthesis protein PhzF
BXU03_RS17115	COG1764	response to oxidative stress
BXU03_RS17130	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BXU03_RS17135	COG1678	Uncharacterized ACR, COG1678
BXU03_RS17145	COG0519	Catalyzes the synthesis of GMP from XMP
BXU03_RS17180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BXU03_RS17225	COG0693	protein deglycase activity
BXU03_RS17245	COG1959	2 iron, 2 sulfur cluster binding
BXU03_RS17250	COG0719	Fe-S assembly protein
BXU03_RS17255	COG0396	ATPase activity
BXU03_RS17260	COG0719	Fe-S assembly protein
BXU03_RS17265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BXU03_RS17280	COG2146	nitrite reductase [NAD(P)H] activity
BXU03_RS17300	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BXU03_RS17315	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BXU03_RS17325	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BXU03_RS17330	COG0174	glutamine synthetase
BXU03_RS17335	COG3328	transposase activity
BXU03_RS17365	COG0326	Molecular chaperone. Has ATPase activity
BXU03_RS17370	COG2207	Transcriptional regulator
BXU03_RS17395	COG2755	lipolytic protein G-D-S-L family
BXU03_RS17395	COG0657	acetylesterase activity
BXU03_RS17420	COG0488	(ABC) transporter
BXU03_RS17475	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BXU03_RS17475	COG4651	solute:proton antiporter activity
BXU03_RS17490	COG4772	TonB-dependent receptor
BXU03_RS17500	COG4264	IucA IucC family
BXU03_RS17505	COG2814	Major facilitator Superfamily
BXU03_RS17515	COG0019	diaminopimelate decarboxylase activity
BXU03_RS17575	COG4206	TonB-dependent receptor
BXU03_RS17615	COG0542	response to heat
BXU03_RS17665	COG0534	Mate efflux family protein
BXU03_RS17680	COG0336	Belongs to the RNA methyltransferase TrmD family
BXU03_RS17685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BXU03_RS17690	COG0228	four-way junction DNA binding
BXU03_RS17715	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BXU03_RS17730	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BXU03_RS17780	COG1555	photosystem II stabilization
BXU03_RS17785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BXU03_RS17800	COG3178	'Phosphotransferase
BXU03_RS17805	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BXU03_RS17815	COG0628	permease
BXU03_RS17825	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BXU03_RS17840	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BXU03_RS17865	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BXU03_RS17875	COG0271	Belongs to the BolA IbaG family
BXU03_RS17885	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BXU03_RS17895	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BXU03_RS17900	COG1137	ATPase activity
BXU03_RS17915	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BXU03_RS17920	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BXU03_RS17925	COG1660	Displays ATPase and GTPase activities
BXU03_RS17935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BXU03_RS17940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BXU03_RS17950	COG2239	Acts as a magnesium transporter
BXU03_RS17960	COG1294	oxidase, subunit
BXU03_RS17965	COG1271	oxidase subunit
BXU03_RS17985	COG1113	amino acid transport
BXU03_RS18000	COG2197	response regulator
BXU03_RS18005	COG0531	amino acid
BXU03_RS18075	COG0754	glutathionylspermidine amidase activity
BXU03_RS18100	COG1842	Phage shock protein A
BXU03_RS18115	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BXU03_RS18120	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BXU03_RS18130	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BXU03_RS18165	COG2201	protein-glutamate methylesterase activity
BXU03_RS18210	COG2801	Transposase and inactivated derivatives
BXU03_RS18230	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BXU03_RS18275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BXU03_RS18280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXU03_RS18305	COG3039	Transposase
BXU03_RS18320	COG0745	RESPONSE REGULATOR receiver
BXU03_RS18325	COG2205	protein histidine kinase activity
BXU03_RS18345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BXU03_RS18380	COG3453	Protein conserved in bacteria
BXU03_RS18380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BXU03_RS18385	COG0725	ABC transporter, periplasmic molybdate-binding protein
BXU03_RS18390	COG4149	molybdate abc transporter
BXU03_RS18395	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BXU03_RS18415	COG0642	Histidine kinase
BXU03_RS18430	COG1028	Short-chain dehydrogenase reductase Sdr
BXU03_RS18440	COG1022	Amp-dependent synthetase and ligase
BXU03_RS18465	COG1376	ErfK ybiS ycfS ynhG family protein
BXU03_RS18470	COG0739	heme binding
BXU03_RS18480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BXU03_RS18485	COG1301	dicarboxylic acid transport
BXU03_RS18505	COG2304	oxidoreductase activity
BXU03_RS18525	COG0714	Associated with various cellular activities
BXU03_RS18570	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BXU03_RS18595	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BXU03_RS18605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BXU03_RS18630	COG1561	YicC-like family, N-terminal region
BXU03_RS18635	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BXU03_RS18650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BXU03_RS18680	COG0006	proline dipeptidase activity
BXU03_RS18705	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BXU03_RS18715	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BXU03_RS18725	COG2912	Transglutaminase-like superfamily
BXU03_RS18730	COG1773	rubredoxin
BXU03_RS18735	COG0352	thiamine-phosphate diphosphorylase activity
BXU03_RS18805	COG0280	phosphate acetyltransferase
BXU03_RS18805	COG0281	malic enzyme
BXU03_RS18825	COG4191	Histidine kinase
BXU03_RS18840	COG0583	DNA-binding transcription factor activity
BXU03_RS18860	COG2197	response regulator
BXU03_RS18870	COG0642	Histidine kinase
BXU03_RS18890	COG2851	Citrate transporter
BXU03_RS18895	COG1028	Short-chain dehydrogenase reductase Sdr
BXU03_RS18900	COG1609	Transcriptional regulator
BXU03_RS18910	COG2211	Major facilitator Superfamily
BXU03_RS18960	COG0726	polysaccharide deacetylase
BXU03_RS18965	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BXU03_RS19000	COG3039	Transposase
BXU03_RS19005	COG3039	Transposase
BXU03_RS19055	COG0242	peptide deformylase activity
BXU03_RS19075	COG0714	Associated with various cellular activities
BXU03_RS19095	COG0537	adenosine 5'-monophosphoramidase activity
BXU03_RS19125	COG0314	molybdopterin synthase activity
BXU03_RS19130	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BXU03_RS19135	COG0315	cyclic pyranopterin monophosphate synthase activity
BXU03_RS19145	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BXU03_RS19150	COG1234	tRNA 3'-trailer cleavage
BXU03_RS19155	COG3642	lipopolysaccharide core region biosynthetic process
BXU03_RS19160	COG0859	PFAM glycosyl transferase family 9
BXU03_RS19170	COG0582	viral genome integration into host DNA
BXU03_RS19230	COG0631	protein serine/threonine phosphatase activity
BXU03_RS19240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BXU03_RS19265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BXU03_RS19305	COG0544	peptidyl-prolyl cis-trans isomerase activity
BXU03_RS19360	COG0473	3-isopropylmalate dehydrogenase activity
BXU03_RS19385	COG4783	chaperone-mediated protein folding
BXU03_RS19400	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BXU03_RS19410	COG0438	transferase activity, transferring glycosyl groups
BXU03_RS19415	COG0671	phosphoesterase, PA-phosphatase related
BXU03_RS19420	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BXU03_RS19440	COG2833	Protein of unknown function (DUF455)
BXU03_RS19460	COG0285	dihydrofolate synthase activity
BXU03_RS19470	COG0588	phosphoglycerate mutase activity
BXU03_RS19505	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BXU03_RS19510	COG4208	sulfate ABC transporter
BXU03_RS19515	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BXU03_RS19520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BXU03_RS19525	COG0156	8-amino-7-oxononanoate synthase activity
BXU03_RS19555	COG0604	alcohol dehydrogenase
BXU03_RS19560	COG1902	pentaerythritol trinitrate reductase activity
BXU03_RS19560	COG0446	pyridine nucleotide-disulphide oxidoreductase
BXU03_RS19660	COG0697	spore germination
BXU03_RS19690	COG3386	PFAM SMP-30 Gluconolaconase
BXU03_RS19710	COG1024	Enoyl-CoA hydratase
BXU03_RS19720	COG0318	PFAM AMP-dependent synthetase and ligase
BXU03_RS19725	COG0583	DNA-binding transcription factor activity
BXU03_RS19765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BXU03_RS19770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BXU03_RS19780	COG2096	Adenosyltransferase
BXU03_RS19785	COG0123	including yeast histone deacetylase and acetoin utilization protein
BXU03_RS19800	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BXU03_RS19810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BXU03_RS19815	COG2967	ApaG domain
BXU03_RS19840	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BXU03_RS19860	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BXU03_RS19880	COG0642	Histidine kinase
BXU03_RS19895	COG4181	ATPase activity
BXU03_RS19905	COG2175	clavaminate synthase activity
BXU03_RS19960	COG0667	Aldo Keto reductase
BXU03_RS19970	COG3039	Transposase
BXU03_RS19980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BXU03_RS19985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXU03_RS20005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BXU03_RS20020	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BXU03_RS20075	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BXU03_RS20080	COG2226	methyltransferase
BXU03_RS20135	COG1028	Short-chain dehydrogenase reductase Sdr
BXU03_RS20135	COG0604	alcohol dehydrogenase
BXU03_RS20135	COG3321	synthase
BXU03_RS20150	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BXU03_RS20165	COG0494	nUDIX hydrolase
BXU03_RS20180	COG1388	LysM domain
BXU03_RS20180	COG4942	peptidase
BXU03_RS20190	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BXU03_RS20205	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BXU03_RS20210	COG1181	Belongs to the D-alanine--D-alanine ligase family
BXU03_RS20215	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BXU03_RS20230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BXU03_RS20235	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BXU03_RS20250	COG3116	cell division
BXU03_RS20255	COG0275	rRNA processing
BXU03_RS20290	COG0792	nuclease activity
BXU03_RS20295	COG1988	membrane-bound metal-dependent
BXU03_RS20300	COG0277	FAD linked oxidase domain protein
BXU03_RS20305	COG0745	RESPONSE REGULATOR receiver
BXU03_RS20310	COG2205	protein histidine kinase activity
BXU03_RS20320	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BXU03_RS20325	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BXU03_RS20350	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BXU03_RS20355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BXU03_RS20360	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BXU03_RS20380	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BXU03_RS20380	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BXU03_RS20400	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BXU03_RS20420	COG0488	(ABC) transporter
BXU03_RS20475	COG2205	protein histidine kinase activity
BXU03_RS20530	COG2205	protein histidine kinase activity
BXU03_RS20545	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BXU03_RS20580	COG3039	Transposase
BXU03_RS20610	COG3039	Transposase
BXU03_RS20710	COG1649	PFAM Uncharacterised BCR, COG1649
BXU03_RS20710	COG0726	polysaccharide deacetylase
BXU03_RS20715	COG1215	transferase activity, transferring glycosyl groups
BXU03_RS20725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BXU03_RS20730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BXU03_RS20735	COG1609	Transcriptional regulator
BXU03_RS20745	COG2188	Transcriptional regulator
BXU03_RS20760	COG3250	beta-galactosidase activity
BXU03_RS20810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BXU03_RS20815	COG4191	Histidine kinase
BXU03_RS20820	COG0784	Response regulator, receiver
BXU03_RS20825	COG4251	negative regulation of phosphorylation
BXU03_RS20830	COG2823	Periplasmic or secreted lipoprotein
BXU03_RS20835	COG0673	inositol 2-dehydrogenase activity
BXU03_RS20840	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BXU03_RS20875	COG1056	cytidyltransferase-related domain
BXU03_RS20875	COG1051	belongs to the nudix hydrolase family
BXU03_RS20900	COG2921	Belongs to the UPF0250 family
BXU03_RS20915	COG1686	Belongs to the peptidase S11 family
BXU03_RS20925	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BXU03_RS20930	COG2951	lytic endotransglycosylase activity
BXU03_RS21000	COG0772	Belongs to the SEDS family
BXU03_RS21015	COG1792	Involved in formation and maintenance of cell shape
BXU03_RS21020	COG1077	Cell shape determining protein MreB Mrl
BXU03_RS21025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXU03_RS21075	COG2199	diguanylate cyclase activity
BXU03_RS21080	COG0308	aminopeptidase N
BXU03_RS21110	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BXU03_RS21140	COG0436	Aminotransferase
BXU03_RS21175	COG1505	serine-type exopeptidase activity
BXU03_RS21200	COG0181	hydroxymethylbilane synthase activity
BXU03_RS21210	COG3275	phosphorelay sensor kinase activity
BXU03_RS21255	COG0659	secondary active sulfate transmembrane transporter activity
BXU03_RS21260	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BXU03_RS21260	COG5297	Belongs to the glycosyl hydrolase family 6
BXU03_RS21345	COG0598	Magnesium transport protein CorA
BXU03_RS21355	COG1113	amino acid transport
BXU03_RS21365	COG5297	Belongs to the glycosyl hydrolase family 6
BXU03_RS21370	COG4305	rare lipoprotein A
BXU03_RS21375	COG0697	spore germination
BXU03_RS21435	COG4221	oxidoreductase activity
BXU03_RS21465	COG0456	acetyltransferase
BXU03_RS21475	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BXU03_RS21520	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BXU03_RS21520	COG2111	Na H antiporter
BXU03_RS21525	COG1006	Multisubunit Na H antiporter MnhC subunit
BXU03_RS21530	COG0651	ATP synthesis coupled electron transport
BXU03_RS21540	COG2212	antiporter activity
BXU03_RS21545	COG1320	monovalent cation:proton antiporter activity
BXU03_RS21560	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BXU03_RS21580	COG3104	oligopeptide transport
BXU03_RS21585	COG3483	tryptophan 2,3-dioxygenase activity
BXU03_RS21595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BXU03_RS21635	COG0183	Belongs to the thiolase family
BXU03_RS21705	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BXU03_RS21710	COG3023	N-Acetylmuramoyl-L-alanine amidase
BXU03_RS21720	COG4948	Mandelate Racemase Muconate Lactonizing
BXU03_RS21750	COG0531	amino acid
BXU03_RS21775	COG4682	membrane
BXU03_RS21780	COG2133	pyrroloquinoline quinone binding
BXU03_RS21825	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BXU03_RS21830	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BXU03_RS21840	COG1610	YqeY-like protein
BXU03_RS21855	COG1295	ribonuclease BN
BXU03_RS21860	COG0358	DNA primase activity
BXU03_RS21925	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BXU03_RS21940	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BXU03_RS21990	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BXU03_RS21995	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BXU03_RS22000	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BXU03_RS22010	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BXU03_RS22015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXU03_RS22025	COG0134	indole-3-glycerol-phosphate synthase activity
BXU03_RS22030	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BXU03_RS22100	COG3328	transposase activity
BXU03_RS22115	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BXU03_RS22115	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BXU03_RS22125	COG1473	amidohydrolase
BXU03_RS22130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXU03_RS22135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BXU03_RS22150	COG5383	Protein conserved in bacteria
BXU03_RS22190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BXU03_RS22195	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BXU03_RS22210	COG0028	Belongs to the TPP enzyme family
BXU03_RS22220	COG4191	Histidine kinase
BXU03_RS22245	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BXU03_RS22260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BXU03_RS22265	COG3177	Filamentation induced by cAMP protein fic
BXU03_RS22280	COG0596	Alpha beta hydrolase
BXU03_RS22285	COG0727	PFAM Uncharacterised protein family (UPF0153)
BXU03_RS22290	COG0318	PFAM AMP-dependent synthetase and ligase
BXU03_RS22295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BXU03_RS22350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BXU03_RS22360	COG0129	dihydroxy-acid dehydratase activity
BXU03_RS22385	COG3039	Transposase
BXU03_RS22395	COG0408	coproporphyrinogen oxidase activity
BXU03_RS22445	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BXU03_RS22510	COG2353	YceI-like domain
BXU03_RS22540	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BXU03_RS22555	COG3386	PFAM SMP-30 Gluconolaconase
BXU03_RS22595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BXU03_RS22610	COG4771	TonB-dependent receptor
BXU03_RS22620	COG0459	protein refolding
BXU03_RS22645	COG1252	NADH dehydrogenase
BXU03_RS22655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BXU03_RS22660	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BXU03_RS22665	COG3437	response regulator, receiver
BXU03_RS22670	COG2177	Part of the ABC transporter FtsEX involved in
BXU03_RS22675	COG2884	Cell division ATP-binding protein ftsE
BXU03_RS22685	COG3118	belongs to the thioredoxin family
BXU03_RS22690	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BXU03_RS22705	COG0729	surface antigen
BXU03_RS22710	COG2911	Protein conserved in bacteria
BXU03_RS22745	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BXU03_RS22760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BXU03_RS22830	COG1733	regulation of RNA biosynthetic process
BXU03_RS22835	COG0702	epimerase
BXU03_RS22870	COG0583	DNA-binding transcription factor activity
BXU03_RS22875	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BXU03_RS22895	COG0745	RESPONSE REGULATOR receiver
BXU03_RS22925	COG1902	pentaerythritol trinitrate reductase activity
BXU03_RS22930	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BXU03_RS22940	COG2814	Major facilitator Superfamily
BXU03_RS22945	COG0583	DNA-binding transcription factor activity
BXU03_RS22965	COG0084	hydrolase, TatD family'
BXU03_RS23010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BXU03_RS23030	COG2072	flavoprotein involved in K transport
BXU03_RS23090	COG4770	biotin carboxylase activity
BXU03_RS23095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BXU03_RS23100	COG1960	acyl-CoA dehydrogenase activity
BXU03_RS23155	COG0523	cobalamin synthesis protein
BXU03_RS23165	COG0697	spore germination
BXU03_RS23175	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BXU03_RS23190	COG4771	TonB-dependent receptor
BXU03_RS23195	COG0457	Tetratricopeptide repeat
BXU03_RS23205	COG0752	glycyl-tRNA synthetase alpha subunit
BXU03_RS23210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BXU03_RS23235	COG0519	Catalyzes the synthesis of GMP from XMP
BXU03_RS23235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BXU03_RS23245	COG0805	protein transport
BXU03_RS23255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BXU03_RS23265	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BXU03_RS23295	COG2974	May be involved in recombination
BXU03_RS23300	COG0037	tRNA processing
BXU03_RS23320	COG3661	Belongs to the glycosyl hydrolase 67 family
BXU03_RS23330	COG4948	Mandelate Racemase Muconate Lactonizing
BXU03_RS23340	COG1472	Belongs to the glycosyl hydrolase 3 family
BXU03_RS23345	COG0246	Mannitol dehydrogenase
BXU03_RS23370	COG3693	PFAM glycoside hydrolase, family 10
BXU03_RS23395	COG2211	Major facilitator Superfamily
BXU03_RS23445	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BXU03_RS23485	COG1846	Transcriptional regulator
BXU03_RS23490	COG1764	response to oxidative stress
BXU03_RS23580	COG3549	Plasmid maintenance system killer
BXU03_RS23590	COG1074	ATP-dependent DNA helicase activity
BXU03_RS23595	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BXU03_RS23635	COG2032	superoxide dismutase activity
BXU03_RS23640	COG2032	superoxide dismutase activity
BXU03_RS23645	COG2204	response regulator
BXU03_RS23650	COG3852	Histidine kinase
BXU03_RS23655	COG0004	ammonium transporteR
BXU03_RS23660	COG0347	Belongs to the P(II) protein family
BXU03_RS23665	COG0174	glutamine synthetase
BXU03_RS23670	COG1968	undecaprenyl-diphosphatase activity
BXU03_RS23715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BXU03_RS23725	COG2062	phosphohistidine phosphatase, SixA
BXU03_RS23730	COG0489	protein tyrosine kinase activity
BXU03_RS23750	COG1396	sequence-specific DNA binding
BXU03_RS23755	COG3550	peptidyl-serine autophosphorylation
BXU03_RS23760	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BXU03_RS23765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BXU03_RS23780	COG0517	IMP dehydrogenase activity
BXU03_RS23780	COG1125	glycine betaine transport
BXU03_RS23795	COG1119	ATPase activity
BXU03_RS23805	COG1752	Esterase of the alpha-beta hydrolase superfamily
BXU03_RS23820	COG3039	Transposase
BXU03_RS23845	COG0656	L-ascorbic acid biosynthetic process
BXU03_RS23850	COG2130	NADP-dependent
BXU03_RS23855	COG0667	Aldo Keto reductase
BXU03_RS23865	COG1187	pseudouridine synthase activity
BXU03_RS23880	COG1643	Atp-dependent helicase
BXU03_RS23885	COG4807	Protein conserved in bacteria
BXU03_RS23890	COG4948	Mandelate Racemase Muconate Lactonizing
BXU03_RS23900	COG0179	Fumarylacetoacetate (FAA) hydrolase
BXU03_RS23905	COG1028	Short-chain dehydrogenase reductase Sdr
BXU03_RS23925	COG3507	Belongs to the glycosyl hydrolase 43 family
BXU03_RS23970	COG3162	membrane
BXU03_RS23975	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BXU03_RS23990	COG0708	Exodeoxyribonuclease III
BXU03_RS24005	COG2091	lysine biosynthetic process via aminoadipic acid
BXU03_RS24015	COG3540	Alkaline phosphatase
BXU03_RS24020	COG0357	Ribosomal RNA small subunit methyltransferase G
BXU03_RS24050	COG2159	amidohydrolase
BXU03_RS24065	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BXU03_RS24070	COG0583	DNA-binding transcription factor activity
BXU03_RS24075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BXU03_RS24095	COG0210	DNA helicase
BXU03_RS24105	COG3039	Transposase
BXU03_RS24120	COG0531	amino acid
BXU03_RS24130	COG1322	Protein conserved in bacteria
BXU03_RS24140	COG0386	Belongs to the glutathione peroxidase family
BXU03_RS24205	COG0793	Belongs to the peptidase S41A family
BXU03_RS24210	COG4942	peptidase
BXU03_RS24220	COG2234	aminopeptidase activity
BXU03_RS24270	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BXU03_RS24275	COG0302	gtp cyclohydrolase
BXU03_RS24300	COG0477	Major facilitator Superfamily
BXU03_RS24370	COG1929	Belongs to the glycerate kinase type-1 family
BXU03_RS24375	COG2271	Major facilitator Superfamily
BXU03_RS24390	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BXU03_RS24400	COG0861	Integral membrane protein TerC family
BXU03_RS24415	COG0584	glycerophosphoryl diester phosphodiesterase
BXU03_RS24425	COG0671	phosphoesterase, PA-phosphatase related
BXU03_RS24430	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BXU03_RS24435	COG0726	polysaccharide deacetylase