locus-tag	class	description
EBA16_RS00025	COG0187	DNA topoisomerase II activity
EBA16_RS00035	COG0501	Belongs to the peptidase M48B family
EBA16_RS00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EBA16_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA16_RS00095	COG3039	Transposase
EBA16_RS00145	COG0793	Belongs to the peptidase S41A family
EBA16_RS00150	COG4942	peptidase
EBA16_RS00160	COG2234	aminopeptidase activity
EBA16_RS00170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA16_RS00185	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA16_RS00195	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA16_RS00205	COG1064	alcohol dehydrogenase
EBA16_RS00235	COG0493	'glutamate synthase
EBA16_RS00240	COG0067	glutamate synthase
EBA16_RS00240	COG0069	glutamate synthase activity
EBA16_RS00240	COG0070	glutamate synthase
EBA16_RS00310	COG1111	helicase
EBA16_RS00310	COG1205	dead DEAH box helicase
EBA16_RS00315	COG1272	protein, Hemolysin III
EBA16_RS00345	COG2032	superoxide dismutase activity
EBA16_RS00350	COG2204	response regulator
EBA16_RS00355	COG3852	Histidine kinase
EBA16_RS00360	COG0004	ammonium transporteR
EBA16_RS00365	COG0347	Belongs to the P(II) protein family
EBA16_RS00370	COG0174	glutamine synthetase
EBA16_RS00375	COG1968	undecaprenyl-diphosphatase activity
EBA16_RS00425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA16_RS00435	COG2062	phosphohistidine phosphatase, SixA
EBA16_RS00440	COG0489	protein tyrosine kinase activity
EBA16_RS00460	COG1396	sequence-specific DNA binding
EBA16_RS00465	COG3550	peptidyl-serine autophosphorylation
EBA16_RS00470	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EBA16_RS00475	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA16_RS00490	COG1125	glycine betaine transport
EBA16_RS00505	COG1119	ATPase activity
EBA16_RS00520	COG1752	Esterase of the alpha-beta hydrolase superfamily
EBA16_RS00530	COG1522	sequence-specific DNA binding
EBA16_RS00535	COG3186	Phenylalanine-4-hydroxylase
EBA16_RS00565	COG1609	Transcriptional regulator
EBA16_RS00605	COG0366	Alpha amylase catalytic
EBA16_RS00610	COG0366	Alpha amylase catalytic
EBA16_RS00620	COG3039	Transposase
EBA16_RS00670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EBA16_RS00675	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EBA16_RS00690	COG0028	Belongs to the TPP enzyme family
EBA16_RS00695	COG4191	Histidine kinase
EBA16_RS00720	COG3039	Transposase
EBA16_RS00730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EBA16_RS00745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA16_RS00750	COG3177	Filamentation induced by cAMP protein fic
EBA16_RS00755	COG0596	Alpha beta hydrolase
EBA16_RS00765	COG0727	PFAM Uncharacterised protein family (UPF0153)
EBA16_RS00770	COG0318	PFAM AMP-dependent synthetase and ligase
EBA16_RS00775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EBA16_RS00790	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA16_RS00805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBA16_RS00820	COG0564	pseudouridine synthase activity
EBA16_RS00850	COG0339	signal peptide processing
EBA16_RS00895	COG4770	biotin carboxylase activity
EBA16_RS00900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EBA16_RS00905	COG1960	acyl-CoA dehydrogenase activity
EBA16_RS00960	COG0697	spore germination
EBA16_RS00970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EBA16_RS00975	COG1846	Transcriptional regulator
EBA16_RS00980	COG1764	response to oxidative stress
EBA16_RS01030	COG0656	L-ascorbic acid biosynthetic process
EBA16_RS01045	COG2130	NADP-dependent
EBA16_RS01060	COG1187	pseudouridine synthase activity
EBA16_RS01075	COG1643	Atp-dependent helicase
EBA16_RS01085	COG4807	Protein conserved in bacteria
EBA16_RS01090	COG2072	flavoprotein involved in K transport
EBA16_RS01110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EBA16_RS01115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA16_RS01155	COG3039	Transposase
EBA16_RS01200	COG0084	hydrolase, TatD family'
EBA16_RS01220	COG0583	DNA-binding transcription factor activity
EBA16_RS01225	COG2814	Major facilitator Superfamily
EBA16_RS01235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EBA16_RS01240	COG1902	pentaerythritol trinitrate reductase activity
EBA16_RS01270	COG0745	RESPONSE REGULATOR receiver
EBA16_RS01290	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA16_RS01295	COG0583	DNA-binding transcription factor activity
EBA16_RS01325	COG0702	epimerase
EBA16_RS01330	COG1733	regulation of RNA biosynthetic process
EBA16_RS01365	COG3039	Transposase
EBA16_RS01400	COG0129	dihydroxy-acid dehydratase activity
EBA16_RS01410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EBA16_RS01480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EBA16_RS01485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EBA16_RS01495	COG3485	protocatechuate 3,4-dioxygenase
EBA16_RS01500	COG3485	protocatechuate 3,4-dioxygenase
EBA16_RS01515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA16_RS01520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EBA16_RS01535	COG1414	Transcriptional regulator
EBA16_RS01575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EBA16_RS01615	COG0156	8-amino-7-oxononanoate synthase activity
EBA16_RS01620	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EBA16_RS01625	COG1040	competence protein
EBA16_RS01630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EBA16_RS01735	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EBA16_RS01810	COG1511	domain protein
EBA16_RS01810	COG3264	Mechanosensitive ion channel
EBA16_RS01820	COG3039	Transposase
EBA16_RS01825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBA16_RS01835	COG2354	Protein conserved in bacteria
EBA16_RS01860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EBA16_RS01885	COG0702	epimerase
EBA16_RS01895	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_RS01940	COG0513	Belongs to the DEAD box helicase family
EBA16_RS01950	COG3039	Transposase
EBA16_RS01980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EBA16_RS01990	COG3483	tryptophan 2,3-dioxygenase activity
EBA16_RS01995	COG3104	oligopeptide transport
EBA16_RS02015	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EBA16_RS02025	COG1320	monovalent cation:proton antiporter activity
EBA16_RS02030	COG2212	antiporter activity
EBA16_RS02040	COG0651	ATP synthesis coupled electron transport
EBA16_RS02045	COG1006	Multisubunit Na H antiporter MnhC subunit
EBA16_RS02050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA16_RS02050	COG2111	Na H antiporter
EBA16_RS02085	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EBA16_RS02095	COG0456	acetyltransferase
EBA16_RS02135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EBA16_RS02140	COG0134	indole-3-glycerol-phosphate synthase activity
EBA16_RS02150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EBA16_RS02155	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EBA16_RS02165	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EBA16_RS02170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EBA16_RS02175	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EBA16_RS02245	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EBA16_RS02265	COG2814	Major facilitator Superfamily
EBA16_RS02275	COG2814	Major facilitator Superfamily
EBA16_RS02280	COG1289	transmembrane transporter activity
EBA16_RS02290	COG0151	Belongs to the GarS family
EBA16_RS02300	COG0138	bifunctional purine biosynthesis protein purh
EBA16_RS02305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EBA16_RS02315	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EBA16_RS02370	COG0439	Biotin carboxylase
EBA16_RS02380	COG0511	ligase activity, forming carbon-carbon bonds
EBA16_RS02385	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EBA16_RS02400	COG1324	tolerance protein
EBA16_RS02420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EBA16_RS02440	COG0534	Mate efflux family protein
EBA16_RS02445	COG0616	signal peptide processing
EBA16_RS02455	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_RS02470	COG0009	L-threonylcarbamoyladenylate synthase
EBA16_RS02475	COG1754	DNA topoisomerase type I activity
EBA16_RS02475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA16_RS02495	COG0758	DNA mediated transformation
EBA16_RS02500	COG1652	LysM domain
EBA16_RS02505	COG0242	peptide deformylase activity
EBA16_RS02510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EBA16_RS02515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBA16_RS02515	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EBA16_RS02565	COG1560	Kdo2-lipid A biosynthetic process
EBA16_RS02575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA16_RS02605	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EBA16_RS02610	COG3118	belongs to the thioredoxin family
EBA16_RS02620	COG2884	Cell division ATP-binding protein ftsE
EBA16_RS02625	COG2177	Part of the ABC transporter FtsEX involved in
EBA16_RS02630	COG3437	response regulator, receiver
EBA16_RS02635	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EBA16_RS02640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA16_RS02645	COG2860	membrane
EBA16_RS02650	COG1252	NADH dehydrogenase
EBA16_RS02675	COG0459	protein refolding
EBA16_RS02690	COG3039	Transposase
EBA16_RS02700	COG3039	Transposase
EBA16_RS02710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EBA16_RS02725	COG3386	PFAM SMP-30 Gluconolaconase
EBA16_RS02740	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA16_RS02785	COG2353	YceI-like domain
EBA16_RS02905	COG4221	oxidoreductase activity
EBA16_RS02965	COG0697	spore germination
EBA16_RS02970	COG4305	rare lipoprotein A
EBA16_RS02975	COG5297	Belongs to the glycosyl hydrolase family 6
EBA16_RS02985	COG1113	amino acid transport
EBA16_RS02995	COG0598	Magnesium transport protein CorA
EBA16_RS03075	COG3300	MHYT domain
EBA16_RS03075	COG5001	Diguanylate cyclase
EBA16_RS03100	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA16_RS03100	COG5297	Belongs to the glycosyl hydrolase family 6
EBA16_RS03105	COG0659	secondary active sulfate transmembrane transporter activity
EBA16_RS03140	COG3275	phosphorelay sensor kinase activity
EBA16_RS03150	COG0181	hydroxymethylbilane synthase activity
EBA16_RS03175	COG1505	serine-type exopeptidase activity
EBA16_RS03185	COG0436	Aminotransferase
EBA16_RS03195	COG2832	Protein of unknown function (DUF454)
EBA16_RS03215	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EBA16_RS03225	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EBA16_RS03260	COG3300	MHYT domain
EBA16_RS03260	COG5001	Diguanylate cyclase
EBA16_RS03265	COG0308	aminopeptidase N
EBA16_RS03280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA16_RS03285	COG1077	Cell shape determining protein MreB Mrl
EBA16_RS03290	COG1792	Involved in formation and maintenance of cell shape
EBA16_RS03305	COG0772	Belongs to the SEDS family
EBA16_RS03330	COG2951	lytic endotransglycosylase activity
EBA16_RS03335	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EBA16_RS03340	COG1686	Belongs to the peptidase S11 family
EBA16_RS03355	COG2921	Belongs to the UPF0250 family
EBA16_RS03380	COG1056	cytidyltransferase-related domain
EBA16_RS03380	COG1051	belongs to the nudix hydrolase family
EBA16_RS03415	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EBA16_RS03420	COG0673	inositol 2-dehydrogenase activity
EBA16_RS03425	COG2823	Periplasmic or secreted lipoprotein
EBA16_RS03430	COG4251	negative regulation of phosphorylation
EBA16_RS03435	COG0784	Response regulator, receiver
EBA16_RS03440	COG4191	Histidine kinase
EBA16_RS03445	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EBA16_RS03470	COG3039	Transposase
EBA16_RS03490	COG3250	beta-galactosidase activity
EBA16_RS03505	COG2188	Transcriptional regulator
EBA16_RS03515	COG1609	Transcriptional regulator
EBA16_RS03520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA16_RS03525	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EBA16_RS03540	COG1215	transferase activity, transferring glycosyl groups
EBA16_RS03545	COG0726	polysaccharide deacetylase
EBA16_RS03545	COG1649	PFAM Uncharacterised BCR, COG1649
EBA16_RS03565	COG3039	Transposase
EBA16_RS03610	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EBA16_RS03650	COG2205	protein histidine kinase activity
EBA16_RS03680	COG3791	Glutathione-dependent formaldehyde-activating
EBA16_RS03695	COG3039	Transposase
EBA16_RS03710	COG0488	(ABC) transporter
EBA16_RS03730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EBA16_RS03740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EBA16_RS03750	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA16_RS03750	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA16_RS03770	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EBA16_RS03775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBA16_RS03780	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EBA16_RS03810	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EBA16_RS03815	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EBA16_RS03825	COG2205	protein histidine kinase activity
EBA16_RS03830	COG0745	RESPONSE REGULATOR receiver
EBA16_RS03860	COG0277	FAD linked oxidase domain protein
EBA16_RS03870	COG0792	nuclease activity
EBA16_RS03910	COG0275	rRNA processing
EBA16_RS03915	COG3116	cell division
EBA16_RS03930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EBA16_RS03935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA16_RS03950	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBA16_RS03955	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA16_RS03960	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EBA16_RS03975	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EBA16_RS03985	COG1196	nuclear chromosome segregation
EBA16_RS03985	COG0741	lytic transglycosylase activity
EBA16_RS03985	COG0739	heme binding
EBA16_RS04000	COG0494	nUDIX hydrolase
EBA16_RS04015	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EBA16_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_RS04030	COG0604	alcohol dehydrogenase
EBA16_RS04030	COG3321	synthase
EBA16_RS04090	COG2226	methyltransferase
EBA16_RS04095	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EBA16_RS04120	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_RS04145	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EBA16_RS04160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA16_RS04170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA16_RS04175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EBA16_RS04185	COG0667	Aldo Keto reductase
EBA16_RS04210	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EBA16_RS04220	COG2175	clavaminate synthase activity
EBA16_RS04230	COG4181	ATPase activity
EBA16_RS04245	COG0642	Histidine kinase
EBA16_RS04260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EBA16_RS04280	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EBA16_RS04300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EBA16_RS04305	COG2967	ApaG domain
EBA16_RS04310	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EBA16_RS04325	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EBA16_RS04340	COG0123	including yeast histone deacetylase and acetoin utilization protein
EBA16_RS04345	COG2096	Adenosyltransferase
EBA16_RS04360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA16_RS04365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA16_RS04385	COG1802	Transcriptional regulator
EBA16_RS04395	COG3384	dioxygenase
EBA16_RS04400	COG0583	DNA-binding transcription factor activity
EBA16_RS04405	COG0318	PFAM AMP-dependent synthetase and ligase
EBA16_RS04415	COG1024	Enoyl-CoA hydratase
EBA16_RS04435	COG3386	PFAM SMP-30 Gluconolaconase
EBA16_RS04485	COG2197	response regulator
EBA16_RS04495	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EBA16_RS04500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EBA16_RS04505	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA16_RS04515	COG0583	DNA-binding transcription factor activity
EBA16_RS04520	COG3634	alkyl hydroperoxide reductase activity
EBA16_RS04530	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA16_RS04570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA16_RS04570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA16_RS04585	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBA16_RS04640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EBA16_RS04650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EBA16_RS04680	COG1295	ribonuclease BN
EBA16_RS04685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA16_RS04690	COG1254	Belongs to the acylphosphatase family
EBA16_RS04705	COG0521	Mo-molybdopterin cofactor biosynthetic process
EBA16_RS04715	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EBA16_RS04720	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EBA16_RS04730	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EBA16_RS04745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EBA16_RS04755	COG0193	aminoacyl-tRNA hydrolase activity
EBA16_RS04760	COG0012	GTP binding
EBA16_RS04795	COG0250	Participates in transcription elongation, termination and antitermination
EBA16_RS04805	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EBA16_RS04810	COG0081	regulation of translation
EBA16_RS04815	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EBA16_RS04825	COG0085	RNA polymerase activity
EBA16_RS04830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EBA16_RS04835	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EBA16_RS04840	COG0049	tRNA binding
EBA16_RS04870	COG0088	Forms part of the polypeptide exit tunnel
EBA16_RS04875	COG0089	rRNA binding
EBA16_RS04880	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EBA16_RS04890	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EBA16_RS04900	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EBA16_RS04905	COG0255	Belongs to the universal ribosomal protein uL29 family
EBA16_RS04910	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EBA16_RS04915	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EBA16_RS04920	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EBA16_RS04955	COG1841	ribosomal large subunit assembly
EBA16_RS04960	COG0200	Binds to the 23S rRNA
EBA16_RS04965	COG0201	protein transport
EBA16_RS04975	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EBA16_RS04980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EBA16_RS04990	COG0203	ribosomal protein L17
EBA16_RS05010	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EBA16_RS05030	COG1217	gtp-binding protein TYPA
EBA16_RS05035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EBA16_RS05045	COG0625	glutathione transferase activity
EBA16_RS05075	COG3039	Transposase
EBA16_RS05095	COG1902	pentaerythritol trinitrate reductase activity
EBA16_RS05095	COG0446	pyridine nucleotide-disulphide oxidoreductase
EBA16_RS05100	COG0604	alcohol dehydrogenase
EBA16_RS05130	COG0156	8-amino-7-oxononanoate synthase activity
EBA16_RS05135	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EBA16_RS05140	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EBA16_RS05145	COG4208	sulfate ABC transporter
EBA16_RS05150	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EBA16_RS05185	COG0406	alpha-ribazole phosphatase activity
EBA16_RS05195	COG0285	dihydrofolate synthase activity
EBA16_RS05215	COG2833	Protein of unknown function (DUF455)
EBA16_RS05240	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBA16_RS05245	COG0671	phosphoesterase, PA-phosphatase related
EBA16_RS05250	COG0438	transferase activity, transferring glycosyl groups
EBA16_RS05260	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EBA16_RS05265	COG5002	protein histidine kinase activity
EBA16_RS05275	COG4783	chaperone-mediated protein folding
EBA16_RS05290	COG0473	3-isopropylmalate dehydrogenase activity
EBA16_RS05330	COG3039	Transposase
EBA16_RS05355	COG0544	peptidyl-prolyl cis-trans isomerase activity
EBA16_RS05395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EBA16_RS05420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA16_RS05435	COG0631	protein serine/threonine phosphatase activity
EBA16_RS05470	COG0859	PFAM glycosyl transferase family 9
EBA16_RS05475	COG3642	lipopolysaccharide core region biosynthetic process
EBA16_RS05480	COG1234	tRNA 3'-trailer cleavage
EBA16_RS05485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EBA16_RS05495	COG0315	cyclic pyranopterin monophosphate synthase activity
EBA16_RS05500	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EBA16_RS05505	COG0314	molybdopterin synthase activity
EBA16_RS05540	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EBA16_RS05550	COG0537	adenosine 5'-monophosphoramidase activity
EBA16_RS05570	COG0714	Associated with various cellular activities
EBA16_RS05590	COG1399	metal-binding, possibly nucleic acid-binding protein
EBA16_RS05615	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_RS05620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBA16_RS05630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EBA16_RS05635	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EBA16_RS05670	COG3829	transcription factor binding
EBA16_RS05710	COG3039	Transposase
EBA16_RS05790	COG0330	HflC and HflK could
EBA16_RS05795	COG0330	HflC and HflK could
EBA16_RS05805	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EBA16_RS05810	COG0308	aminopeptidase N
EBA16_RS05825	COG0732	type I restriction modification DNA specificity domain
EBA16_RS05840	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EBA16_RS05925	COG0587	DNA-directed DNA polymerase activity
EBA16_RS05945	COG1297	OPT oligopeptide transporter protein
EBA16_RS05965	COG0823	Involved in the tonB-independent uptake of proteins
EBA16_RS05965	COG1506	peptidase
EBA16_RS05975	COG2207	Transcriptional regulator
EBA16_RS05975	COG1917	Cupin 2, conserved barrel domain protein
EBA16_RS06020	COG0753	catalase activity
EBA16_RS06060	COG3551	Protein conserved in bacteria
EBA16_RS06090	COG2194	sulfuric ester hydrolase activity
EBA16_RS06100	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EBA16_RS06105	COG0745	RESPONSE REGULATOR receiver
EBA16_RS06110	COG0642	Histidine kinase
EBA16_RS06120	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EBA16_RS06125	COG2894	cell division
EBA16_RS06140	COG4585	Histidine kinase
EBA16_RS06145	COG2197	response regulator
EBA16_RS06160	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EBA16_RS06185	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EBA16_RS06260	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_RS06285	COG3039	Transposase
EBA16_RS06310	COG3179	chitinase
EBA16_RS06465	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EBA16_RS06480	COG1842	Phage shock protein A
EBA16_RS06505	COG0754	glutathionylspermidine amidase activity
EBA16_RS06585	COG0531	amino acid
EBA16_RS06590	COG2197	response regulator
EBA16_RS06595	COG2267	carboxylic ester hydrolase activity
EBA16_RS06605	COG1113	amino acid transport
EBA16_RS06635	COG3039	Transposase
EBA16_RS06645	COG1294	oxidase, subunit
EBA16_RS06655	COG2239	Acts as a magnesium transporter
EBA16_RS06665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA16_RS06670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA16_RS06685	COG3039	Transposase
EBA16_RS06700	COG1660	Displays ATPase and GTPase activities
EBA16_RS06710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA16_RS06725	COG1137	ATPase activity
EBA16_RS06730	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EBA16_RS06740	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EBA16_RS06750	COG0271	Belongs to the BolA IbaG family
EBA16_RS06755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EBA16_RS06780	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EBA16_RS06795	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EBA16_RS06805	COG0628	permease
EBA16_RS06815	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EBA16_RS06820	COG3178	'Phosphotransferase
EBA16_RS06830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA16_RS06835	COG1555	photosystem II stabilization
EBA16_RS06855	COG3039	Transposase
EBA16_RS06865	COG2146	nitrite reductase [NAD(P)H] activity
EBA16_RS06875	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EBA16_RS06880	COG0719	Fe-S assembly protein
EBA16_RS06885	COG0396	ATPase activity
EBA16_RS06890	COG0719	Fe-S assembly protein
EBA16_RS06895	COG1959	2 iron, 2 sulfur cluster binding
EBA16_RS06950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EBA16_RS06985	COG0519	Catalyzes the synthesis of GMP from XMP
EBA16_RS07000	COG1678	Uncharacterized ACR, COG1678
EBA16_RS07005	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EBA16_RS07020	COG1764	response to oxidative stress
EBA16_RS07030	COG0384	phenazine biosynthesis protein PhzF
EBA16_RS07040	COG0527	aspartate kinase activity
EBA16_RS07070	COG3039	Transposase
EBA16_RS07080	COG0142	geranyltranstransferase activity
EBA16_RS07085	COG0629	single-stranded DNA binding
EBA16_RS07090	COG2203	Gaf domain
EBA16_RS07090	COG3706	GGDEF domain
EBA16_RS07090	COG4251	negative regulation of phosphorylation
EBA16_RS07090	COG5001	Diguanylate cyclase
EBA16_RS07135	COG2879	small protein
EBA16_RS07140	COG1966	Carbon starvation protein
EBA16_RS07145	COG1741	Belongs to the pirin family
EBA16_RS07240	COG1515	deoxyribonuclease V activity
EBA16_RS07260	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EBA16_RS07265	COG2202	Pas domain
EBA16_RS07265	COG2200	EAL domain
EBA16_RS07265	COG2199	diguanylate cyclase activity
EBA16_RS07270	COG0835	chemotaxis
EBA16_RS07275	COG0840	transmembrane signaling receptor activity
EBA16_RS07285	COG2198	Histidine kinase
EBA16_RS07285	COG0643	Histidine kinase
EBA16_RS07300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EBA16_RS07310	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EBA16_RS07345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EBA16_RS07350	COG0735	belongs to the Fur family
EBA16_RS07380	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_RS07470	COG3039	Transposase
EBA16_RS07530	COG5001	Diguanylate cyclase
EBA16_RS07530	COG5002	protein histidine kinase activity
EBA16_RS07535	COG1187	pseudouridine synthase activity
EBA16_RS07555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EBA16_RS07565	COG0475	glutathione-regulated potassium exporter activity
EBA16_RS07570	COG5002	protein histidine kinase activity
EBA16_RS07570	COG5000	phosphorelay sensor kinase activity
EBA16_RS07575	COG0745	RESPONSE REGULATOR receiver
EBA16_RS07580	COG1538	Outer membrane efflux protein
EBA16_RS07605	COG1132	(ABC) transporter
EBA16_RS07630	COG3039	Transposase
EBA16_RS07675	COG3118	belongs to the thioredoxin family
EBA16_RS07705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EBA16_RS07725	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EBA16_RS07750	COG2968	Membrane
EBA16_RS07765	COG3164	Protein of unknown function
EBA16_RS07775	COG0312	modulator of DNA gyrase
EBA16_RS07780	COG3028	Belongs to the UPF0307 family
EBA16_RS07785	COG0312	modulator of DNA gyrase
EBA16_RS07800	COG4104	PAAR repeat-containing protein
EBA16_RS07810	COG0142	geranyltranstransferase activity
EBA16_RS07815	COG1722	exodeoxyribonuclease VII activity
EBA16_RS07820	COG0037	tRNA processing
EBA16_RS07825	COG1785	Belongs to the alkaline phosphatase family
EBA16_RS07830	COG1301	dicarboxylic acid transport
EBA16_RS07835	COG4106	trans-aconitate 2-methyltransferase activity
EBA16_RS07850	COG0791	NLP P60 protein
EBA16_RS07855	COG0791	NLP P60 protein
EBA16_RS07860	COG1047	Peptidyl-prolyl cis-trans
EBA16_RS07865	COG2311	Membrane
EBA16_RS07870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA16_RS07900	COG3039	Transposase
EBA16_RS07910	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_RS07940	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_RS07945	COG3039	Transposase
EBA16_RS07960	COG0489	protein tyrosine kinase activity
EBA16_RS07970	COG0717	Belongs to the dCTP deaminase family
EBA16_RS07985	COG3039	Transposase
EBA16_RS08005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EBA16_RS08015	COG3039	Transposase
EBA16_RS08025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA16_RS08040	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_RS08050	COG0433	COG0433 Predicted ATPase
EBA16_RS08080	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA16_RS08085	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EBA16_RS08090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBA16_RS08095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EBA16_RS08115	COG0101	tRNA pseudouridine synthase activity
EBA16_RS08120	COG0135	phosphoribosylanthranilate isomerase activity
EBA16_RS08130	COG0133	tryptophan synthase activity
EBA16_RS08150	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EBA16_RS08155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBA16_RS08210	COG0149	triose-phosphate isomerase activity
EBA16_RS08225	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA16_RS08235	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA16_RS08240	COG0649	NAD binding
EBA16_RS08245	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EBA16_RS08250	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EBA16_RS08255	COG1034	ATP synthesis coupled electron transport
EBA16_RS08260	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EBA16_RS08265	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA16_RS08290	COG1007	ATP synthesis coupled electron transport
EBA16_RS08300	COG0779	Required for maturation of 30S ribosomal subunits
EBA16_RS08305	COG0195	Participates in both transcription termination and antitermination
EBA16_RS08310	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EBA16_RS08325	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EBA16_RS08330	COG1185	polyribonucleotide nucleotidyltransferase activity
EBA16_RS08365	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA16_RS08375	COG2095	MarC family integral membrane protein
EBA16_RS08390	COG3039	Transposase
EBA16_RS08395	COG1611	Belongs to the LOG family
EBA16_RS08435	COG4969	Belongs to the N-Me-Phe pilin family
EBA16_RS08440	COG0556	nucleotide-excision repair
EBA16_RS08470	COG3723	Recombinational DNA repair protein, rece pathway
EBA16_RS08570	COG0270	DNA (cytosine-5-)-methyltransferase activity
EBA16_RS08785	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EBA16_RS08795	COG2986	histidine ammonia-lyase
EBA16_RS08800	COG1228	amidohydrolase
EBA16_RS08845	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EBA16_RS08850	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EBA16_RS08855	COG1605	Chorismate mutase
EBA16_RS08855	COG0077	Prephenate dehydratase
EBA16_RS08860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EBA16_RS08885	COG3039	Transposase
EBA16_RS08895	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EBA16_RS08910	COG0583	DNA-binding transcription factor activity
EBA16_RS08925	COG2336	PFAM SpoVT AbrB
EBA16_RS08965	COG0840	transmembrane signaling receptor activity
EBA16_RS08990	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EBA16_RS08995	COG4191	Histidine kinase
EBA16_RS08995	COG0784	Response regulator, receiver
EBA16_RS09010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA16_RS09030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA16_RS09045	COG1595	DNA-templated transcription, initiation
EBA16_RS09095	COG2244	polysaccharide biosynthetic process
EBA16_RS09125	COG2264	protein methyltransferase activity
EBA16_RS09135	COG0438	transferase activity, transferring glycosyl groups
EBA16_RS09150	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EBA16_RS09155	COG1132	(ABC) transporter
EBA16_RS09165	COG0477	Major facilitator Superfamily
EBA16_RS09185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBA16_RS09200	COG1253	flavin adenine dinucleotide binding
EBA16_RS09215	COG0306	phosphate transporter
EBA16_RS09245	COG0504	CTP synthase activity
EBA16_RS09250	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EBA16_RS09255	COG0148	phosphopyruvate hydratase activity
EBA16_RS09260	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EBA16_RS09275	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EBA16_RS09285	COG2840	Smr protein MutS2
EBA16_RS09290	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EBA16_RS09295	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBA16_RS09300	COG1238	metal cluster binding
EBA16_RS09315	COG1534	Rna-binding protein
EBA16_RS09320	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EBA16_RS09330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EBA16_RS09345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EBA16_RS09350	COG1546	Belongs to the CinA family
EBA16_RS09365	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EBA16_RS09375	COG2137	regulation of response to DNA damage stimulus
EBA16_RS09380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EBA16_RS09385	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EBA16_RS09435	COG1741	Belongs to the pirin family
EBA16_RS09440	COG0583	DNA-binding transcription factor activity
EBA16_RS09465	COG0351	phosphomethylpyrimidine kinase
EBA16_RS09465	COG0352	thiamine-phosphate diphosphorylase activity
EBA16_RS09475	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EBA16_RS09480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EBA16_RS09495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA16_RS09505	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EBA16_RS09510	COG3734	2-keto-3-deoxy-galactonokinase
EBA16_RS09520	COG4948	Mandelate Racemase Muconate Lactonizing
EBA16_RS09525	COG0800	Aldolase
EBA16_RS09550	COG1070	Carbohydrate kinase
EBA16_RS09560	COG0477	Major facilitator Superfamily
EBA16_RS09580	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA16_RS09585	COG1469	GTP cyclohydrolase I activity
EBA16_RS09595	COG0617	tRNA 3'-terminal CCA addition
EBA16_RS09615	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EBA16_RS09645	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA16_RS09665	COG4251	negative regulation of phosphorylation
EBA16_RS09665	COG3706	GGDEF domain
EBA16_RS09665	COG2203	Gaf domain
EBA16_RS09665	COG5001	Diguanylate cyclase
EBA16_RS09675	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA16_RS09685	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EBA16_RS09700	COG0671	phosphoesterase, PA-phosphatase related
EBA16_RS09720	COG1794	racemase activity, acting on amino acids and derivatives
EBA16_RS09730	COG0697	spore germination
EBA16_RS09735	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EBA16_RS09760	COG1012	belongs to the aldehyde dehydrogenase family
EBA16_RS09825	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EBA16_RS09840	COG0124	histidyl-tRNA synthetase
EBA16_RS09860	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EBA16_RS09875	COG0131	Imidazoleglycerol-phosphate dehydratase
EBA16_RS09875	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EBA16_RS09885	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EBA16_RS09895	COG0140	phosphoribosyl-ATP diphosphatase activity
EBA16_RS09895	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EBA16_RS09915	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EBA16_RS09920	COG0235	Class ii aldolase
EBA16_RS09925	COG0531	amino acid
EBA16_RS09930	COG0531	amino acid
EBA16_RS09940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EBA16_RS09945	COG0277	FAD linked oxidase domain protein
EBA16_RS09970	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EBA16_RS10025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBA16_RS10030	COG2258	MOSC domain
EBA16_RS10035	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EBA16_RS10040	COG0505	Belongs to the CarA family
EBA16_RS10050	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EBA16_RS10055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA16_RS10065	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EBA16_RS10080	COG3279	Response regulator of the LytR AlgR family
EBA16_RS10105	COG2205	protein histidine kinase activity
EBA16_RS10105	COG0784	Response regulator, receiver
EBA16_RS10105	COG2198	Histidine kinase
EBA16_RS10110	COG1024	Enoyl-CoA hydratase
EBA16_RS10115	COG0318	PFAM AMP-dependent synthetase and ligase
EBA16_RS10145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA16_RS10175	COG0840	transmembrane signaling receptor activity
EBA16_RS10185	COG0835	chemotaxis
EBA16_RS10200	COG0840	transmembrane signaling receptor activity
EBA16_RS10205	COG0840	transmembrane signaling receptor activity
EBA16_RS10210	COG0840	transmembrane signaling receptor activity
EBA16_RS10225	COG0840	transmembrane signaling receptor activity
EBA16_RS10235	COG0840	transmembrane signaling receptor activity
EBA16_RS10240	COG0840	transmembrane signaling receptor activity
EBA16_RS10270	COG0840	transmembrane signaling receptor activity
EBA16_RS10275	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_RS10295	COG0745	RESPONSE REGULATOR receiver
EBA16_RS10305	COG0835	chemotaxis
EBA16_RS10310	COG1192	Involved in chromosome partitioning
EBA16_RS10315	COG1360	Flagellar Motor Protein
EBA16_RS10320	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EBA16_RS10340	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA16_RS10380	COG3039	Transposase
EBA16_RS10445	COG0643	Histidine kinase
EBA16_RS10445	COG2198	Histidine kinase
EBA16_RS10445	COG0784	Response regulator, receiver
EBA16_RS10500	COG1684	flagellar biosynthetic protein fliR
EBA16_RS10515	COG3190	flagellar
EBA16_RS10565	COG1677	Flagellar hook-basal body complex protein FliE
EBA16_RS10600	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_RS10610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA16_RS10630	COG2201	protein-glutamate methylesterase activity
EBA16_RS10660	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EBA16_RS10665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EBA16_RS10680	COG3951	Flagellar rod assembly protein muramidase FlgJ
EBA16_RS10680	COG1705	Flagellar rod assembly protein muramidase FlgJ
EBA16_RS10685	COG1706	bacterial-type flagellum-dependent cell motility
EBA16_RS10690	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EBA16_RS10705	COG4787	bacterial-type flagellum-dependent cell motility
EBA16_RS10715	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EBA16_RS10720	COG1558	bacterial-type flagellum-dependent cell motility
EBA16_RS10730	COG0784	Response regulator, receiver
EBA16_RS10730	COG0835	chemotaxis
EBA16_RS10750	COG5002	protein histidine kinase activity
EBA16_RS10760	COG4585	Histidine kinase
EBA16_RS10795	COG0482	sulfurtransferase activity
EBA16_RS10810	COG0542	response to heat
EBA16_RS10835	COG0492	ferredoxin-NADP+ reductase activity
EBA16_RS10840	COG1674	ftsk spoiiie
EBA16_RS10865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EBA16_RS10885	COG0038	chloride channel
EBA16_RS10890	COG0183	Belongs to the thiolase family
EBA16_RS10895	COG1024	Enoyl-CoA hydratase
EBA16_RS10895	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA16_RS10910	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EBA16_RS10930	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA16_RS10935	COG1160	GTP binding
EBA16_RS10940	COG0303	'Molybdopterin
EBA16_RS10950	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EBA16_RS10960	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_RS10985	COG0746	molybdenum cofactor guanylyltransferase activity
EBA16_RS11010	COG1648	precorrin-2 dehydrogenase activity
EBA16_RS11010	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EBA16_RS11050	COG3039	Transposase
EBA16_RS11075	COG5001	Diguanylate cyclase
EBA16_RS11095	COG4566	intracellular signal transduction
EBA16_RS11225	COG1024	Enoyl-CoA hydratase
EBA16_RS11230	COG1024	Enoyl-CoA hydratase
EBA16_RS11240	COG1024	Enoyl-CoA hydratase
EBA16_RS11255	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EBA16_RS11365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA16_RS11370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA16_RS11420	COG1858	cytochrome C peroxidase
EBA16_RS11450	COG0515	serine threonine protein kinase
EBA16_RS11455	COG0631	protein serine/threonine phosphatase activity
EBA16_RS11515	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_RS11530	COG3039	Transposase
EBA16_RS11615	COG3039	Transposase
EBA16_RS11630	COG2154	pterin-4-alpha-carbinolamine dehydratase
EBA16_RS11645	COG3064	Membrane
EBA16_RS11655	COG1530	ribonuclease E activity
EBA16_RS11670	COG1054	Belongs to the UPF0176 family
EBA16_RS11690	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EBA16_RS11730	COG0322	excinuclease ABC activity
EBA16_RS11740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBA16_RS11750	COG1663	tetraacyldisaccharide 4'-kinase activity
EBA16_RS11765	COG0811	peptide transport
EBA16_RS11790	COG4591	ABC-type transport system involved in lipoprotein release permease component
EBA16_RS11805	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EBA16_RS11820	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EBA16_RS11835	COG0354	folic acid binding
EBA16_RS11850	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA16_RS11860	COG0363	glucosamine-6-phosphate deaminase activity
EBA16_RS11865	COG0129	dihydroxy-acid dehydratase activity
EBA16_RS11870	COG0800	Aldolase
EBA16_RS11950	COG0784	Response regulator, receiver
EBA16_RS11950	COG2205	protein histidine kinase activity
EBA16_RS11965	COG2183	response to ionizing radiation
EBA16_RS11975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA16_RS11975	COG0723	plastoquinol--plastocyanin reductase activity
EBA16_RS11990	COG3243	poly(R)-hydroxyalkanoic acid synthase
EBA16_RS12000	COG1183	phosphatidylcholine synthase activity
EBA16_RS12005	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_RS12020	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EBA16_RS12030	COG0668	transmembrane transport
EBA16_RS12050	COG1914	H( )-stimulated, divalent metal cation uptake system
EBA16_RS12080	COG0583	DNA-binding transcription factor activity
EBA16_RS12105	COG0583	DNA-binding transcription factor activity
EBA16_RS12110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA16_RS12115	COG3002	Belongs to the UPF0753 family
EBA16_RS12120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA16_RS12120	COG0519	Catalyzes the synthesis of GMP from XMP
EBA16_RS12130	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EBA16_RS12145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EBA16_RS12155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA16_RS12160	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EBA16_RS12170	COG0776	regulation of translation
EBA16_RS12175	COG0539	negative regulation of cytoplasmic translation
EBA16_RS12180	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EBA16_RS12195	COG2957	Belongs to the agmatine deiminase family
EBA16_RS12205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA16_RS12230	COG0395	ABC-type sugar transport system, permease component
EBA16_RS12235	COG1175	transmembrane transport
EBA16_RS12265	COG2350	Protein conserved in bacteria
EBA16_RS12270	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EBA16_RS12275	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EBA16_RS12280	COG1187	pseudouridine synthase activity
EBA16_RS12300	COG0436	Aminotransferase
EBA16_RS12305	COG4133	protoheme IX ABC transporter activity
EBA16_RS12355	COG1278	Cold shock
EBA16_RS12365	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EBA16_RS12370	COG4988	ABC transporter
EBA16_RS12380	COG1271	oxidase subunit
EBA16_RS12435	COG0165	Argininosuccinate lyase
EBA16_RS12450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EBA16_RS12455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA16_RS12460	COG0137	argininosuccinate synthase activity
EBA16_RS12465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EBA16_RS12480	COG2166	iron-sulfur cluster assembly
EBA16_RS12505	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EBA16_RS12520	COG4302	ethanolamine ammonia-lyase activity
EBA16_RS12535	COG4677	pectinesterase activity
EBA16_RS12560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EBA16_RS12565	COG0402	S-adenosylhomocysteine deaminase activity
EBA16_RS12585	COG1509	lysine 2,3-aminomutase activity
EBA16_RS12590	COG3300	MHYT domain
EBA16_RS12590	COG5001	Diguanylate cyclase
EBA16_RS12605	COG0483	inositol monophosphate 1-phosphatase activity
EBA16_RS12610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA16_RS12635	COG0488	(ABC) transporter
EBA16_RS12640	COG0513	Belongs to the DEAD box helicase family
EBA16_RS12650	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EBA16_RS12660	COG0625	glutathione transferase activity
EBA16_RS12670	COG1671	Belongs to the UPF0178 family
EBA16_RS12675	COG4681	YaeQ
EBA16_RS12680	COG2081	HI0933 family
EBA16_RS12685	COG1716	ATPase activity
EBA16_RS12685	COG5001	Diguanylate cyclase
EBA16_RS12690	COG0501	Belongs to the peptidase M48B family
EBA16_RS12700	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_RS12720	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EBA16_RS12725	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA16_RS12730	COG0802	atpase or kinase
EBA16_RS12735	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EBA16_RS12735	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EBA16_RS12740	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA16_RS12760	COG3039	Transposase
EBA16_RS12770	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA16_RS12815	COG0835	chemotaxis
EBA16_RS12820	COG0840	transmembrane signaling receptor activity
EBA16_RS12850	COG2969	positive regulation of protein catabolic process
EBA16_RS12855	COG0625	glutathione transferase activity
EBA16_RS12860	COG2857	Cytochrome c1
EBA16_RS12865	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EBA16_RS12870	COG0723	plastoquinol--plastocyanin reductase activity
EBA16_RS12880	COG0741	lytic transglycosylase activity
EBA16_RS12905	COG1702	phosphate starvation-inducible protein PhoH
EBA16_RS12925	COG4535	Mg2 and Co2 transporter CorC
EBA16_RS12940	COG1012	belongs to the aldehyde dehydrogenase family
EBA16_RS12945	COG1177	transmembrane transport
EBA16_RS12950	COG1176	ABC-type spermidine putrescine transport system, permease component I
EBA16_RS12960	COG3842	ATPase activity
EBA16_RS12990	COG3039	Transposase
EBA16_RS13015	COG0174	glutamine synthetase
EBA16_RS13020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA16_RS13030	COG0477	Major facilitator Superfamily
EBA16_RS13040	COG0243	molybdopterin cofactor binding
EBA16_RS13050	COG2223	nitrite transmembrane transporter activity
EBA16_RS13060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EBA16_RS13065	COG1121	(ABC) transporter
EBA16_RS13075	COG2733	membrane
EBA16_RS13080	COG0784	Response regulator, receiver
EBA16_RS13080	COG2205	protein histidine kinase activity
EBA16_RS13080	COG5002	protein histidine kinase activity
EBA16_RS13090	COG3039	Transposase
EBA16_RS13140	COG3039	Transposase
EBA16_RS13150	COG2902	Dehydrogenase
EBA16_RS13160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA16_RS13165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA16_RS13180	COG1609	Transcriptional regulator
EBA16_RS13185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA16_RS13185	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA16_RS13190	COG1105	Belongs to the carbohydrate kinase PfkB family
EBA16_RS13195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA16_RS13195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA16_RS13245	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBA16_RS13255	COG1862	Preprotein translocase
EBA16_RS13260	COG0343	queuine tRNA-ribosyltransferase activity
EBA16_RS13325	COG0405	Gamma-glutamyltransferase
EBA16_RS13330	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EBA16_RS13345	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EBA16_RS13350	COG0742	ribosomal rna small subunit methyltransferase
EBA16_RS13355	COG0326	Molecular chaperone. Has ATPase activity
EBA16_RS13400	COG4206	TonB-dependent receptor
EBA16_RS13455	COG3039	Transposase
EBA16_RS13460	COG3039	Transposase
EBA16_RS13470	COG0531	amino acid
EBA16_RS13485	COG0006	proline dipeptidase activity
EBA16_RS13495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA16_RS13510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA16_RS13515	COG3938	Belongs to the proline racemase family
EBA16_RS13525	COG0552	protein localization to endoplasmic reticulum
EBA16_RS13540	COG1194	a g-specific adenine glycosylase
EBA16_RS13550	COG0784	Response regulator, receiver
EBA16_RS13550	COG4191	Histidine kinase
EBA16_RS13555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EBA16_RS13580	COG3040	lipid binding
EBA16_RS13590	COG1960	acyl-CoA dehydrogenase activity
EBA16_RS13600	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EBA16_RS13630	COG0438	transferase activity, transferring glycosyl groups
EBA16_RS13640	COG0438	transferase activity, transferring glycosyl groups
EBA16_RS13645	COG0438	transferase activity, transferring glycosyl groups
EBA16_RS13700	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EBA16_RS13715	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EBA16_RS13740	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EBA16_RS13755	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EBA16_RS13760	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EBA16_RS13765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EBA16_RS13770	COG3115	cell septum assembly
EBA16_RS13790	COG0360	Binds together with S18 to 16S ribosomal RNA
EBA16_RS13795	COG0316	Belongs to the HesB IscA family
EBA16_RS13830	COG0288	reversible hydration of carbon dioxide
EBA16_RS13855	COG3844	kynureninase activity
EBA16_RS13865	COG2925	Exonuclease
EBA16_RS13875	COG0667	Aldo Keto reductase
EBA16_RS13905	COG0116	Belongs to the methyltransferase superfamily
EBA16_RS13905	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBA16_RS13950	COG0494	nUDIX hydrolase
EBA16_RS13960	COG1024	Enoyl-CoA hydratase
EBA16_RS13970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EBA16_RS13975	COG0659	secondary active sulfate transmembrane transporter activity
EBA16_RS14000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EBA16_RS14005	COG0573	inorganic phosphate transmembrane transporter activity
EBA16_RS14020	COG0704	Plays a role in the regulation of phosphate uptake
EBA16_RS14030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA16_RS14040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA16_RS14055	COG0557	exoribonuclease II activity
EBA16_RS14085	COG1960	acyl-CoA dehydrogenase activity
EBA16_RS14090	COG2226	methyltransferase
EBA16_RS14095	COG0646	methionine synthase
EBA16_RS14095	COG1410	methionine synthase
EBA16_RS14100	COG0646	methionine synthase
EBA16_RS14100	COG1410	methionine synthase
EBA16_RS14110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA16_RS14120	COG1609	Transcriptional regulator
EBA16_RS14135	COG2900	Belongs to the SlyX family
EBA16_RS14150	COG0386	Belongs to the glutathione peroxidase family
EBA16_RS14160	COG1725	Transcriptional regulator
EBA16_RS14165	COG1131	(ABC) transporter
EBA16_RS14205	COG3039	Transposase
EBA16_RS14235	COG2850	peptidyl-arginine hydroxylation
EBA16_RS14270	COG1132	(ABC) transporter
EBA16_RS14300	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EBA16_RS14310	COG0484	heat shock protein binding
EBA16_RS14315	COG0443	Heat shock 70 kDa protein
EBA16_RS14320	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EBA16_RS14330	COG0497	DNA recombination
EBA16_RS14340	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA16_RS14350	COG2914	Belongs to the UPF0125 (RnfH) family
EBA16_RS14360	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EBA16_RS14385	COG3039	Transposase
EBA16_RS14430	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EBA16_RS14445	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EBA16_RS14455	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EBA16_RS14460	COG0174	glutamine synthetase
EBA16_RS14525	COG0415	Belongs to the DNA photolyase family
EBA16_RS14530	COG0305	Participates in initiation and elongation during chromosome replication
EBA16_RS14540	COG0367	asparagine synthase
EBA16_RS14570	COG0084	hydrolase, TatD family'
EBA16_RS14575	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EBA16_RS14615	COG0840	transmembrane signaling receptor activity
EBA16_RS14630	COG3039	Transposase
EBA16_RS14645	COG3039	Transposase
EBA16_RS14675	COG0386	Belongs to the glutathione peroxidase family
EBA16_RS14775	COG2814	Major facilitator Superfamily
EBA16_RS14780	COG1566	PFAM secretion protein HlyD family protein
EBA16_RS14795	COG2207	Transcriptional regulator
EBA16_RS14825	COG4774	siderophore transport
EBA16_RS14835	COG0367	asparagine synthase
EBA16_RS14840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA16_RS14850	COG1393	Belongs to the ArsC family
EBA16_RS14910	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EBA16_RS14925	COG0233	cytoplasmic translational termination
EBA16_RS14935	COG0575	Belongs to the CDS family
EBA16_RS14940	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EBA16_RS14945	COG0750	zinc metalloprotease
EBA16_RS14965	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBA16_RS14970	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBA16_RS14990	COG0825	malonyl-CoA metabolic process
EBA16_RS15015	COG1981	membrane
EBA16_RS15065	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA16_RS15080	COG2040	homocysteine
EBA16_RS15085	COG0833	amino acid
EBA16_RS15090	COG0346	lactoylglutathione lyase activity
EBA16_RS15100	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBA16_RS15100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBA16_RS15110	COG2878	Part of a membrane complex involved in electron transport
EBA16_RS15130	COG1595	DNA-templated transcription, initiation
EBA16_RS15155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA16_RS15170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA16_RS15175	COG0251	oxidation-reduction process
EBA16_RS15185	COG0392	lysyltransferase activity
EBA16_RS15185	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EBA16_RS15225	COG2814	Major facilitator Superfamily
EBA16_RS15230	COG1902	pentaerythritol trinitrate reductase activity
EBA16_RS15245	COG2824	Alkylphosphonate utilization operon protein PhnA
EBA16_RS15255	COG1047	Peptidyl-prolyl cis-trans
EBA16_RS15295	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EBA16_RS15310	COG1451	nucleotide metabolic process
EBA16_RS15330	COG0183	Belongs to the thiolase family
EBA16_RS15360	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EBA16_RS15360	COG1793	dna ligase
EBA16_RS15370	COG1793	dna ligase
EBA16_RS15375	COG1201	RNA secondary structure unwinding
EBA16_RS15395	COG1278	Cold shock
EBA16_RS15400	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EBA16_RS15415	COG3046	protein related to deoxyribodipyrimidine photolyase
EBA16_RS15420	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EBA16_RS15430	COG2954	triphosphatase activity
EBA16_RS15445	COG1381	Involved in DNA repair and RecF pathway recombination
EBA16_RS15475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA16_RS15490	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA16_RS15490	COG1024	Enoyl-CoA hydratase
EBA16_RS15510	COG1024	Enoyl-CoA hydratase
EBA16_RS15515	COG1960	acyl-CoA dehydrogenase activity
EBA16_RS15590	COG2353	YceI-like domain
EBA16_RS15615	COG1760	l-serine dehydratase
EBA16_RS15625	COG0626	cystathionine gamma-synthase activity
EBA16_RS15630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA16_RS15635	COG0739	heme binding
EBA16_RS15645	COG1272	protein, Hemolysin III
EBA16_RS15665	COG0516	GMP reductase activity
EBA16_RS15665	COG0517	IMP dehydrogenase activity
EBA16_RS15670	COG0463	Glycosyl transferase, family 2
EBA16_RS15680	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EBA16_RS15690	COG4771	TonB-dependent receptor
EBA16_RS15695	COG1309	transcriptional regulator
EBA16_RS15705	COG1960	acyl-CoA dehydrogenase activity
EBA16_RS15735	COG0509	glycine decarboxylation via glycine cleavage system
EBA16_RS15750	COG0330	HflC and HflK could
EBA16_RS15760	COG1742	UPF0060 membrane protein
EBA16_RS15765	COG3956	TIGRFAM MazG family protein
EBA16_RS15775	COG0494	nUDIX hydrolase
EBA16_RS15785	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EBA16_RS15790	COG0837	glucose binding
EBA16_RS15805	COG1388	LysM domain
EBA16_RS15805	COG3858	chitin binding
EBA16_RS15825	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA16_RS15850	COG2801	Transposase and inactivated derivatives
EBA16_RS15860	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_RS15875	COG3039	Transposase
EBA16_RS15935	COG3537	Alpha-1,2-mannosidase
EBA16_RS15980	COG3142	Participates in the control of copper homeostasis
EBA16_RS15985	COG1446	asparaginase
EBA16_RS15995	COG2304	oxidoreductase activity
EBA16_RS16020	COG2198	Histidine kinase
EBA16_RS16020	COG0784	Response regulator, receiver
EBA16_RS16020	COG0643	Histidine kinase
EBA16_RS16025	COG0840	transmembrane signaling receptor activity
EBA16_RS16030	COG0835	chemotaxis
EBA16_RS16045	COG0189	ligase activity
EBA16_RS16055	COG1397	ADP-ribosylglycohydrolase
EBA16_RS16065	COG1199	ATP-dependent helicase activity
EBA16_RS16075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EBA16_RS16080	COG1215	transferase activity, transferring glycosyl groups
EBA16_RS16090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA16_RS16140	COG1643	Atp-dependent helicase
EBA16_RS16145	COG0783	Belongs to the Dps family
EBA16_RS16155	COG0514	ATP-dependent DNA helicase (RecQ)
EBA16_RS16170	COG3039	Transposase
EBA16_RS16185	COG1187	pseudouridine synthase activity
EBA16_RS16225	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EBA16_RS16235	COG0602	queuosine metabolic process
EBA16_RS16245	COG2885	chlorophyll binding
EBA16_RS16250	COG0823	Involved in the tonB-independent uptake of proteins
EBA16_RS16260	COG0848	biopolymer transport protein
EBA16_RS16270	COG0824	Thioesterase
EBA16_RS16275	COG2255	four-way junction helicase activity
EBA16_RS16290	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EBA16_RS16315	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EBA16_RS16330	COG0477	Major facilitator Superfamily
EBA16_RS16365	COG0488	(ABC) transporter
EBA16_RS16395	COG4651	solute:proton antiporter activity
EBA16_RS16395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EBA16_RS16440	COG4772	TonB-dependent receptor
EBA16_RS16450	COG4264	IucA IucC family
EBA16_RS16455	COG2814	Major facilitator Superfamily
EBA16_RS16465	COG0019	diaminopimelate decarboxylase activity
EBA16_RS16520	COG4206	TonB-dependent receptor
EBA16_RS16555	COG0542	response to heat
EBA16_RS16580	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EBA16_RS16590	COG0534	Mate efflux family protein
EBA16_RS16605	COG0336	Belongs to the RNA methyltransferase TrmD family
EBA16_RS16610	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EBA16_RS16615	COG0228	four-way junction DNA binding
EBA16_RS16640	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EBA16_RS16650	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA16_RS16690	COG2172	sigma factor antagonist activity
EBA16_RS16695	COG1366	Belongs to the anti-sigma-factor antagonist family
EBA16_RS16700	COG1366	Belongs to the anti-sigma-factor antagonist family
EBA16_RS16710	COG0326	Molecular chaperone. Has ATPase activity
EBA16_RS16715	COG2207	Transcriptional regulator
EBA16_RS16770	COG3209	COG3209 Rhs family protein
EBA16_RS16785	COG3209	COG3209 Rhs family protein
EBA16_RS16805	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EBA16_RS16810	COG1845	cytochrome c oxidase, subunit III
EBA16_RS16815	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EBA16_RS16830	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EBA16_RS16835	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EBA16_RS16850	COG0728	peptidoglycan biosynthetic process
EBA16_RS16855	COG0268	Binds directly to 16S ribosomal RNA
EBA16_RS16860	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EBA16_RS16865	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EBA16_RS16875	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EBA16_RS16880	COG0824	Thioesterase
EBA16_RS16895	COG1946	Acyl-CoA thioesterase
EBA16_RS16905	COG1595	DNA-templated transcription, initiation
EBA16_RS16920	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EBA16_RS16960	COG1877	trehalose-phosphatase activity
EBA16_RS16965	COG3387	PFAM Glycoside hydrolase 15-related
EBA16_RS17000	COG0564	pseudouridine synthase activity
EBA16_RS17005	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA16_RS17010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA16_RS17010	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EBA16_RS17025	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EBA16_RS17030	COG0045	succinate-CoA ligase (ADP-forming) activity
EBA16_RS17070	COG2194	sulfuric ester hydrolase activity
EBA16_RS17075	COG4969	Belongs to the N-Me-Phe pilin family
EBA16_RS17085	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EBA16_RS17090	COG0237	dephospho-CoA kinase activity
EBA16_RS17095	COG2205	protein histidine kinase activity
EBA16_RS17100	COG0745	RESPONSE REGULATOR receiver
EBA16_RS17120	COG3039	Transposase
EBA16_RS17145	COG3039	Transposase
EBA16_RS17160	COG2801	Transposase and inactivated derivatives
EBA16_RS17170	COG3039	Transposase
EBA16_RS17195	COG2022	thiamine diphosphate biosynthetic process
EBA16_RS17210	COG3273	potassium ion transport
EBA16_RS17210	COG0471	metal ion transport
EBA16_RS17240	COG1970	mechanosensitive ion channel activity
EBA16_RS17275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA16_RS17290	COG0308	aminopeptidase N
EBA16_RS17295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA16_RS17305	COG0529	Catalyzes the synthesis of activated sulfate
EBA16_RS17305	COG2895	sulfate adenylyltransferase (ATP) activity
EBA16_RS17310	COG0175	sulfate reduction
EBA16_RS17315	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA16_RS17320	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EBA16_RS17325	COG0175	sulfate reduction
EBA16_RS17345	COG0784	Response regulator, receiver
EBA16_RS17345	COG2198	Histidine kinase
EBA16_RS17345	COG2205	protein histidine kinase activity
EBA16_RS17385	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EBA16_RS17390	COG3588	fructose-bisphosphate aldolase
EBA16_RS17400	COG0469	pyruvate kinase activity
EBA16_RS17425	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EBA16_RS17435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA16_RS17435	COG3453	Protein conserved in bacteria
EBA16_RS17440	COG0725	ABC transporter, periplasmic molybdate-binding protein
EBA16_RS17445	COG4149	molybdate abc transporter
EBA16_RS17450	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EBA16_RS17470	COG0642	Histidine kinase
EBA16_RS17485	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_RS17495	COG1022	Amp-dependent synthetase and ligase
EBA16_RS17520	COG1376	ErfK ybiS ycfS ynhG family protein
EBA16_RS17525	COG0739	heme binding
EBA16_RS17540	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EBA16_RS17545	COG1301	dicarboxylic acid transport
EBA16_RS17565	COG2304	oxidoreductase activity
EBA16_RS17585	COG0714	Associated with various cellular activities
EBA16_RS17620	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EBA16_RS17655	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EBA16_RS17665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA16_RS17685	COG1561	YicC-like family, N-terminal region
EBA16_RS17690	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EBA16_RS17705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EBA16_RS17735	COG0006	proline dipeptidase activity
EBA16_RS17780	COG2912	Transglutaminase-like superfamily
EBA16_RS17785	COG1773	rubredoxin
EBA16_RS17790	COG0352	thiamine-phosphate diphosphorylase activity
EBA16_RS17800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EBA16_RS17815	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EBA16_RS17860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EBA16_RS17885	COG0671	phosphoesterase, PA-phosphatase related
EBA16_RS17900	COG3781	membrane
EBA16_RS17910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBA16_RS17925	COG3039	Transposase
EBA16_RS17940	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EBA16_RS17950	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EBA16_RS17975	COG3710	Transcriptional regulator
EBA16_RS17980	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EBA16_RS17990	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EBA16_RS18020	COG2226	methyltransferase
EBA16_RS18025	COG0066	3-isopropylmalate dehydratase activity
EBA16_RS18030	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EBA16_RS18050	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBA16_RS18055	COG1538	Outer membrane efflux protein
EBA16_RS18060	COG1519	Transferase
EBA16_RS18065	COG1560	Kdo2-lipid A biosynthetic process
EBA16_RS18085	COG3039	Transposase
EBA16_RS18095	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_RS18160	COG3039	Transposase
EBA16_RS18175	COG0281	malic enzyme
EBA16_RS18175	COG0280	phosphate acetyltransferase
EBA16_RS18195	COG4191	Histidine kinase
EBA16_RS18210	COG0583	DNA-binding transcription factor activity
EBA16_RS18235	COG2197	response regulator
EBA16_RS18245	COG0642	Histidine kinase
EBA16_RS18265	COG2851	Citrate transporter
EBA16_RS18270	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_RS18280	COG1609	Transcriptional regulator
EBA16_RS18290	COG2211	Major facilitator Superfamily
EBA16_RS18320	COG0436	Aminotransferase
EBA16_RS18340	COG0726	polysaccharide deacetylase
EBA16_RS18345	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA16_RS18365	COG0402	S-adenosylhomocysteine deaminase activity
EBA16_RS18415	COG0242	peptide deformylase activity
EBA16_RS18420	COG3039	Transposase
EBA16_RS18455	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EBA16_RS18515	COG2188	Transcriptional regulator
EBA16_RS18530	COG1450	Type ii and iii secretion system protein
EBA16_RS18545	COG3166	PFAM Fimbrial assembly family protein
EBA16_RS18550	COG3156	type II secretion system protein K
EBA16_RS18555	COG4795	General secretion pathway protein
EBA16_RS18560	COG2165	general secretion pathway protein
EBA16_RS18565	COG4970	Tfp pilus assembly protein FimT
EBA16_RS18570	COG2165	general secretion pathway protein
EBA16_RS18575	COG1459	type II secretion system
EBA16_RS18585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA16_RS18590	COG1404	Belongs to the peptidase S8 family
EBA16_RS18595	COG5295	Hep Hag repeat protein
EBA16_RS18605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBA16_RS18605	COG0047	phosphoribosylformylglycinamidine synthase activity
EBA16_RS18615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EBA16_RS18620	COG4974	Belongs to the 'phage' integrase family
EBA16_RS18635	COG0795	lipopolysaccharide-transporting ATPase activity
EBA16_RS18645	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBA16_RS18670	COG0525	valine-tRNA ligase activity
EBA16_RS18700	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_RS18710	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_RS18735	COG1183	phosphatidylcholine synthase activity
EBA16_RS18745	COG0442	prolyl-tRNA aminoacylation
EBA16_RS18760	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA16_RS18765	COG1127	ABC transporter
EBA16_RS18770	COG3218	ABC-type transport auxiliary lipoprotein component
EBA16_RS18770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA16_RS18815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBA16_RS18820	COG0662	Cupin 2, conserved barrel domain protein
EBA16_RS18820	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EBA16_RS18850	COG2086	electron transfer activity
EBA16_RS18920	COG0626	cystathionine gamma-synthase activity
EBA16_RS18950	COG0625	glutathione transferase activity
EBA16_RS18965	COG0513	Belongs to the DEAD box helicase family
EBA16_RS18975	COG0720	synthase
EBA16_RS18985	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EBA16_RS18990	COG1956	GAF domain-containing protein
EBA16_RS19000	COG0546	phosphoglycolate phosphatase activity
EBA16_RS19030	COG0339	signal peptide processing
EBA16_RS19080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA16_RS19145	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EBA16_RS19150	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EBA16_RS19155	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EBA16_RS19165	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EBA16_RS19175	COG0356	it plays a direct role in the translocation of protons across the membrane
EBA16_RS19195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EBA16_RS19205	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBA16_RS19240	COG2011	ABC-type metal ion transport system permease component
EBA16_RS19250	COG0697	spore germination
EBA16_RS19285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EBA16_RS19290	COG1187	pseudouridine synthase activity
EBA16_RS19295	COG2813	Specifically methylates the guanine in position
EBA16_RS19325	COG2205	protein histidine kinase activity
EBA16_RS19325	COG2202	Pas domain
EBA16_RS19350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA16_RS19400	COG0745	RESPONSE REGULATOR receiver
EBA16_RS19415	COG1404	Belongs to the peptidase S8 family
EBA16_RS19430	COG0842	Transport permease protein
EBA16_RS19435	COG1131	(ABC) transporter
EBA16_RS19440	COG0025	NhaP-type Na H and K H
EBA16_RS19450	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EBA16_RS19460	COG1573	uracil-dna glycosylase
EBA16_RS19470	COG3384	dioxygenase
EBA16_RS19495	COG3590	peptidase
EBA16_RS19515	COG0531	amino acid
EBA16_RS19540	COG3685	Protein conserved in bacteria
EBA16_RS19545	COG3546	catalase activity
EBA16_RS19570	COG3039	Transposase
EBA16_RS19600	COG1271	oxidase subunit
EBA16_RS19605	COG1294	oxidase, subunit
EBA16_RS19635	COG1063	alcohol dehydrogenase
EBA16_RS19730	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EBA16_RS19730	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EBA16_RS19740	COG1473	amidohydrolase
EBA16_RS19745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA16_RS19750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA16_RS19775	COG5383	Protein conserved in bacteria
EBA16_RS19830	COG3023	N-Acetylmuramoyl-L-alanine amidase
EBA16_RS19840	COG4948	Mandelate Racemase Muconate Lactonizing
EBA16_RS19870	COG0531	amino acid
EBA16_RS19890	COG4682	membrane
EBA16_RS19895	COG2133	pyrroloquinoline quinone binding
EBA16_RS19915	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EBA16_RS19920	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EBA16_RS19930	COG1610	YqeY-like protein
EBA16_RS19950	COG1295	ribonuclease BN
EBA16_RS19955	COG0358	DNA primase activity
EBA16_RS20020	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EBA16_RS20035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EBA16_RS20100	COG0739	heme binding
EBA16_RS20115	COG2211	Major facilitator Superfamily
EBA16_RS20120	COG0708	Exodeoxyribonuclease III
EBA16_RS20135	COG1192	Involved in chromosome partitioning
EBA16_RS20140	COG1475	DNA binding
EBA16_RS20160	COG0463	Glycosyl transferase, family 2
EBA16_RS20185	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EBA16_RS20210	COG4221	oxidoreductase activity
EBA16_RS20250	COG1166	arginine decarboxylase activity
EBA16_RS20255	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EBA16_RS20300	COG0606	chelatase, subunit chli
EBA16_RS20325	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EBA16_RS20345	COG3039	Transposase
EBA16_RS20405	COG1090	epimerase
EBA16_RS20415	COG0642	Histidine kinase
EBA16_RS20430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA16_RS20465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBA16_RS20475	COG1595	DNA-templated transcription, initiation
EBA16_RS20480	COG0753	catalase activity
EBA16_RS20505	COG0697	spore germination
EBA16_RS20530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA16_RS20535	COG0180	Tryptophanyl-tRNA synthetase
EBA16_RS20540	COG3237	CsbD-like
EBA16_RS20555	COG0010	Belongs to the arginase family
EBA16_RS20575	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EBA16_RS20590	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EBA16_RS20595	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EBA16_RS20595	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EBA16_RS20605	COG3228	Belongs to the MtfA family
EBA16_RS20635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA16_RS20690	COG3039	Transposase
EBA16_RS20695	COG1566	PFAM secretion protein HlyD family protein
EBA16_RS20710	COG1199	ATP-dependent helicase activity
EBA16_RS20755	COG0583	DNA-binding transcription factor activity
EBA16_RS20805	COG0625	glutathione transferase activity
EBA16_RS20815	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_RS20845	COG4555	ABC transporter
EBA16_RS20855	COG1476	TRANSCRIPTIONal
EBA16_RS20875	COG1230	cation diffusion facilitator family transporter
EBA16_RS20880	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA16_RS20885	COG1131	(ABC) transporter
EBA16_RS20890	COG0842	Transport permease protein
EBA16_RS20900	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EBA16_RS20935	COG2951	lytic endotransglycosylase activity
EBA16_RS20950	COG1196	nuclear chromosome segregation
EBA16_RS20955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA16_RS20965	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA16_RS20980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EBA16_RS20980	COG1042	CoA-binding domain protein
EBA16_RS20980	COG0045	succinate-CoA ligase (ADP-forming) activity
EBA16_RS20990	COG2239	Acts as a magnesium transporter
EBA16_RS21015	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA16_RS21020	COG3387	PFAM Glycoside hydrolase 15-related
EBA16_RS21035	COG3100	YcgL domain-containing protein
EBA16_RS21040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EBA16_RS21050	COG0463	Glycosyl transferase, family 2
EBA16_RS21060	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_RS21090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBA16_RS21105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBA16_RS21155	COG0408	coproporphyrinogen oxidase activity
EBA16_RS21235	COG0210	DNA helicase
EBA16_RS21255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA16_RS21270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EBA16_RS21285	COG2159	amidohydrolase
EBA16_RS21315	COG0357	Ribosomal RNA small subunit methyltransferase G
EBA16_RS21320	COG3540	Alkaline phosphatase
EBA16_RS21330	COG2091	lysine biosynthetic process via aminoadipic acid
EBA16_RS21345	COG0708	Exodeoxyribonuclease III
EBA16_RS21360	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EBA16_RS21365	COG3162	membrane
EBA16_RS21420	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_RS21425	COG0179	Fumarylacetoacetate (FAA) hydrolase
EBA16_RS21435	COG4948	Mandelate Racemase Muconate Lactonizing
EBA16_RS21440	COG3254	rhamnose metabolic process
EBA16_RS21445	COG0738	Major facilitator superfamily
EBA16_RS21450	COG1414	Transcriptional regulator
EBA16_RS21460	COG2205	protein histidine kinase activity
EBA16_RS21470	COG3459	Glycosyltransferase 36 associated
EBA16_RS21475	COG2211	Major facilitator Superfamily
EBA16_RS21480	COG3265	gluconokinase activity
EBA16_RS21485	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA16_RS21515	COG3039	Transposase
EBA16_RS21525	COG3039	Transposase
EBA16_RS21530	COG2911	Protein conserved in bacteria
EBA16_RS21535	COG0729	surface antigen
EBA16_RS21540	COG4771	TonB-dependent receptor
EBA16_RS21545	COG0457	Tetratricopeptide repeat
EBA16_RS21560	COG0752	glycyl-tRNA synthetase alpha subunit
EBA16_RS21565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA16_RS21575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA16_RS21575	COG0519	Catalyzes the synthesis of GMP from XMP
EBA16_RS21585	COG0805	protein transport
EBA16_RS21590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA16_RS21595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA16_RS21605	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EBA16_RS21635	COG2974	May be involved in recombination
EBA16_RS21640	COG0037	tRNA processing
EBA16_RS21665	COG3661	Belongs to the glycosyl hydrolase 67 family
EBA16_RS21675	COG4948	Mandelate Racemase Muconate Lactonizing
EBA16_RS21685	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA16_RS21690	COG0246	Mannitol dehydrogenase
EBA16_RS21725	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_RS21750	COG3693	PFAM glycoside hydrolase, family 10
EBA16_RS21775	COG2211	Major facilitator Superfamily
EBA16_RS21790	COG3039	Transposase
EBA16_RS21820	COG2937	Belongs to the GPAT DAPAT family
EBA16_RS21855	COG0284	orotidine-5'-phosphate decarboxylase activity
EBA16_RS21860	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EBA16_RS21865	COG3132	Protein of unknown function, DUF480
EBA16_RS21880	COG0210	DNA helicase
EBA16_RS21895	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EBA16_RS21905	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EBA16_RS21960	COG0676	glucose-6-phosphate 1-epimerase activity
EBA16_RS21975	COG0730	response to heat
EBA16_RS22010	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EBA16_RS22015	COG0302	gtp cyclohydrolase
EBA16_RS22045	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_RS22055	COG0477	Major facilitator Superfamily
EBA16_RS22070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA16_RS22115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA16_RS22165	COG3237	CsbD-like
EBA16_RS22190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA16_RS22220	COG1304	FMN binding
EBA16_RS22245	COG4772	TonB-dependent receptor
EBA16_RS22255	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EBA16_RS22285	COG3039	Transposase
EBA16_RS22340	COG0564	pseudouridine synthase activity
EBA16_RS22355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA16_RS22370	COG3039	Transposase
EBA16_RS22390	COG3039	Transposase
EBA16_RS22415	COG3039	Transposase
EBA16_RS22495	COG1074	ATP-dependent DNA helicase activity
EBA16_RS22500	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EBA16_RS22505	COG1116	anion transmembrane transporter activity
EBA16_RS22515	COG3039	Transposase
EBA16_RS22520	COG3039	Transposase
EBA16_RS22535	COG1136	(ABC) transporter
EBA16_RS22555	COG1127	ABC transporter
EBA16_RS22560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA16_RS22565	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA16_RS22580	COG2853	Lipoprotein
EBA16_RS22610	COG0386	Belongs to the glutathione peroxidase family
EBA16_RS22620	COG1322	Protein conserved in bacteria
EBA16_RS22625	COG3039	Transposase
EBA16_RS22650	COG1929	Belongs to the glycerate kinase type-1 family
EBA16_RS22655	COG2271	Major facilitator Superfamily
EBA16_RS22670	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBA16_RS22680	COG0861	Integral membrane protein TerC family
EBA16_RS22690	COG0584	glycerophosphoryl diester phosphodiesterase
EBA16_RS22700	COG0671	phosphoesterase, PA-phosphatase related
EBA16_RS22705	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EBA16_RS22710	COG0726	polysaccharide deacetylase