locus-tag	class	description
NO935_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NO935_RS00020	COG0187	DNA topoisomerase II activity
NO935_RS00030	COG0501	Belongs to the peptidase M48B family
NO935_RS00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NO935_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NO935_RS00080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NO935_RS00090	COG4772	TonB-dependent receptor
NO935_RS00105	COG3039	Transposase
NO935_RS00110	COG1304	FMN binding
NO935_RS00130	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NO935_RS00140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NO935_RS00235	COG2826	transposase and inactivated derivatives, IS30 family
NO935_RS00260	COG3039	Transposase
NO935_RS00270	COG1090	epimerase
NO935_RS00290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NO935_RS00400	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NO935_RS00480	COG1511	domain protein
NO935_RS00480	COG3264	Mechanosensitive ion channel
NO935_RS00495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NO935_RS00500	COG2354	Protein conserved in bacteria
NO935_RS00505	COG1649	PFAM Uncharacterised BCR, COG1649
NO935_RS00525	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NO935_RS00550	COG0702	epimerase
NO935_RS00565	COG1858	cytochrome C peroxidase
NO935_RS00635	COG0513	Belongs to the DEAD box helicase family
NO935_RS00640	COG3039	Transposase
NO935_RS00685	COG1136	(ABC) transporter
NO935_RS00710	COG3039	Transposase
NO935_RS00725	COG1136	(ABC) transporter
NO935_RS00765	COG1272	protein, Hemolysin III
NO935_RS00770	COG1205	dead DEAH box helicase
NO935_RS00770	COG1111	helicase
NO935_RS00830	COG0067	glutamate synthase
NO935_RS00830	COG0069	glutamate synthase activity
NO935_RS00830	COG0070	glutamate synthase
NO935_RS00835	COG0493	'glutamate synthase
NO935_RS00885	COG1609	Transcriptional regulator
NO935_RS00910	COG0366	Alpha amylase catalytic
NO935_RS00915	COG0366	Alpha amylase catalytic
NO935_RS00960	COG0606	chelatase, subunit chli
NO935_RS01005	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NO935_RS01010	COG1166	arginine decarboxylase activity
NO935_RS01075	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NO935_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_RS01125	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NO935_RS01140	COG0210	DNA helicase
NO935_RS01155	COG3132	Protein of unknown function, DUF480
NO935_RS01160	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NO935_RS01165	COG0284	orotidine-5'-phosphate decarboxylase activity
NO935_RS01200	COG2937	Belongs to the GPAT DAPAT family
NO935_RS01205	COG3321	synthase
NO935_RS01205	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_RS01205	COG0604	alcohol dehydrogenase
NO935_RS01240	COG1752	Esterase of the alpha-beta hydrolase superfamily
NO935_RS01250	COG1119	ATPase activity
NO935_RS01265	COG0517	IMP dehydrogenase activity
NO935_RS01265	COG1125	glycine betaine transport
NO935_RS01280	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NO935_RS01285	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
NO935_RS01290	COG3550	peptidyl-serine autophosphorylation
NO935_RS01295	COG1396	sequence-specific DNA binding
NO935_RS01315	COG0489	protein tyrosine kinase activity
NO935_RS01320	COG2062	phosphohistidine phosphatase, SixA
NO935_RS01330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NO935_RS01370	COG1968	undecaprenyl-diphosphatase activity
NO935_RS01375	COG0174	glutamine synthetase
NO935_RS01380	COG0347	Belongs to the P(II) protein family
NO935_RS01385	COG0004	ammonium transporteR
NO935_RS01390	COG3852	Histidine kinase
NO935_RS01395	COG2204	response regulator
NO935_RS01400	COG2032	superoxide dismutase activity
NO935_RS01410	COG2032	superoxide dismutase activity
NO935_RS01445	COG1196	nuclear chromosome segregation
NO935_RS01450	COG1196	nuclear chromosome segregation
NO935_RS01460	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NO935_RS01465	COG1074	ATP-dependent DNA helicase activity
NO935_RS01475	COG3549	Plasmid maintenance system killer
NO935_RS01560	COG1764	response to oxidative stress
NO935_RS01565	COG1846	Transcriptional regulator
NO935_RS01655	COG2211	Major facilitator Superfamily
NO935_RS01680	COG3693	PFAM glycoside hydrolase, family 10
NO935_RS01705	COG0246	Mannitol dehydrogenase
NO935_RS01710	COG1472	Belongs to the glycosyl hydrolase 3 family
NO935_RS01720	COG4948	Mandelate Racemase Muconate Lactonizing
NO935_RS01730	COG3661	Belongs to the glycosyl hydrolase 67 family
NO935_RS01750	COG0037	tRNA processing
NO935_RS01755	COG2974	May be involved in recombination
NO935_RS01780	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NO935_RS01790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NO935_RS01800	COG0805	protein transport
NO935_RS01810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NO935_RS01810	COG0519	Catalyzes the synthesis of GMP from XMP
NO935_RS01825	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NO935_RS01830	COG0752	glycyl-tRNA synthetase alpha subunit
NO935_RS01840	COG0457	Tetratricopeptide repeat
NO935_RS01845	COG4771	TonB-dependent receptor
NO935_RS01875	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NO935_RS01895	COG0523	cobalamin synthesis protein
NO935_RS01955	COG1960	acyl-CoA dehydrogenase activity
NO935_RS01960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NO935_RS01965	COG4770	biotin carboxylase activity
NO935_RS02025	COG2351	hydroxyisourate hydrolase activity
NO935_RS02050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NO935_RS02095	COG0084	hydrolase, TatD family'
NO935_RS02115	COG2814	Major facilitator Superfamily
NO935_RS02125	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NO935_RS02130	COG1902	pentaerythritol trinitrate reductase activity
NO935_RS02160	COG0745	RESPONSE REGULATOR receiver
NO935_RS02180	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NO935_RS02185	COG0583	DNA-binding transcription factor activity
NO935_RS02215	COG0702	epimerase
NO935_RS02220	COG1733	regulation of RNA biosynthetic process
NO935_RS02270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO935_RS02320	COG2911	Protein conserved in bacteria
NO935_RS02325	COG0729	surface antigen
NO935_RS02340	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NO935_RS02345	COG3118	belongs to the thioredoxin family
NO935_RS02355	COG2884	Cell division ATP-binding protein ftsE
NO935_RS02360	COG2177	Part of the ABC transporter FtsEX involved in
NO935_RS02365	COG2201	protein-glutamate methylesterase activity
NO935_RS02370	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NO935_RS02375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NO935_RS02385	COG1252	NADH dehydrogenase
NO935_RS02410	COG0459	protein refolding
NO935_RS02430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NO935_RS02460	COG3386	PFAM SMP-30 Gluconolaconase
NO935_RS02475	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NO935_RS02505	COG2353	YceI-like domain
NO935_RS02545	COG2201	protein-glutamate methylesterase activity
NO935_RS02595	COG0408	coproporphyrinogen oxidase activity
NO935_RS02630	COG0129	dihydroxy-acid dehydratase activity
NO935_RS02640	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NO935_RS02670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NO935_RS02675	COG0318	PFAM AMP-dependent synthetase and ligase
NO935_RS02680	COG0727	PFAM Uncharacterised protein family (UPF0153)
NO935_RS02685	COG0596	Alpha beta hydrolase
NO935_RS02710	COG3177	Filamentation induced by cAMP protein fic
NO935_RS02715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NO935_RS02730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NO935_RS02755	COG4191	Histidine kinase
NO935_RS02760	COG0028	Belongs to the TPP enzyme family
NO935_RS02775	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NO935_RS02780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NO935_RS02815	COG5383	Protein conserved in bacteria
NO935_RS02825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NO935_RS02830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NO935_RS02835	COG1473	amidohydrolase
NO935_RS02845	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NO935_RS02845	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NO935_RS02920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NO935_RS02935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NO935_RS02940	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NO935_RS02950	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
NO935_RS02955	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NO935_RS02960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NO935_RS03010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NO935_RS03025	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NO935_RS03090	COG3039	Transposase
NO935_RS03115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NO935_RS03135	COG0534	Mate efflux family protein
NO935_RS03140	COG0616	signal peptide processing
NO935_RS03150	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_RS03170	COG0009	L-threonylcarbamoyladenylate synthase
NO935_RS03175	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NO935_RS03175	COG1754	DNA topoisomerase type I activity
NO935_RS03190	COG2922	Belongs to the Smg family
NO935_RS03195	COG0758	DNA mediated transformation
NO935_RS03200	COG1652	LysM domain
NO935_RS03205	COG0242	peptide deformylase activity
NO935_RS03210	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NO935_RS03215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NO935_RS03215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NO935_RS03265	COG1560	Kdo2-lipid A biosynthetic process
NO935_RS03275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NO935_RS03410	COG0358	DNA primase activity
NO935_RS03415	COG1295	ribonuclease BN
NO935_RS03425	COG3293	Transposase
NO935_RS03430	COG1610	YqeY-like protein
NO935_RS03440	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NO935_RS03445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NO935_RS03490	COG2133	pyrroloquinoline quinone binding
NO935_RS03495	COG4682	membrane
NO935_RS03525	COG0531	amino acid
NO935_RS03555	COG4948	Mandelate Racemase Muconate Lactonizing
NO935_RS03565	COG3023	N-Acetylmuramoyl-L-alanine amidase
NO935_RS03570	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NO935_RS03640	COG0183	Belongs to the thiolase family
NO935_RS03685	COG3483	tryptophan 2,3-dioxygenase activity
NO935_RS03690	COG3104	oligopeptide transport
NO935_RS03710	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NO935_RS03720	COG1320	monovalent cation:proton antiporter activity
NO935_RS03725	COG2212	antiporter activity
NO935_RS03735	COG0651	ATP synthesis coupled electron transport
NO935_RS03740	COG1006	Multisubunit Na H antiporter MnhC subunit
NO935_RS03745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NO935_RS03745	COG2111	Na H antiporter
NO935_RS03790	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NO935_RS03800	COG0456	acetyltransferase
NO935_RS03820	COG2801	Transposase and inactivated derivatives
NO935_RS03830	COG4221	oxidoreductase activity
NO935_RS03890	COG0697	spore germination
NO935_RS03895	COG4305	rare lipoprotein A
NO935_RS03900	COG5297	Belongs to the glycosyl hydrolase family 6
NO935_RS03910	COG1113	amino acid transport
NO935_RS03920	COG0598	Magnesium transport protein CorA
NO935_RS03990	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NO935_RS03990	COG5297	Belongs to the glycosyl hydrolase family 6
NO935_RS03995	COG0659	secondary active sulfate transmembrane transporter activity
NO935_RS04035	COG3275	phosphorelay sensor kinase activity
NO935_RS04045	COG0181	hydroxymethylbilane synthase activity
NO935_RS04070	COG1505	serine-type exopeptidase activity
NO935_RS04085	COG3039	Transposase
NO935_RS04090	COG0436	Aminotransferase
NO935_RS04120	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NO935_RS04150	COG0308	aminopeptidase N
NO935_RS04155	COG2199	diguanylate cyclase activity
NO935_RS04200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NO935_RS04205	COG1077	Cell shape determining protein MreB Mrl
NO935_RS04210	COG1792	Involved in formation and maintenance of cell shape
NO935_RS04225	COG0772	Belongs to the SEDS family
NO935_RS04265	COG1388	LysM domain
NO935_RS04265	COG3409	Peptidoglycan-binding domain 1 protein
NO935_RS04265	COG5632	N-Acetylmuramoyl-L-alanine amidase
NO935_RS04290	COG2951	lytic endotransglycosylase activity
NO935_RS04295	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NO935_RS04300	COG1686	Belongs to the peptidase S11 family
NO935_RS04315	COG2921	Belongs to the UPF0250 family
NO935_RS04340	COG1056	cytidyltransferase-related domain
NO935_RS04340	COG1051	belongs to the nudix hydrolase family
NO935_RS04375	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NO935_RS04380	COG0673	inositol 2-dehydrogenase activity
NO935_RS04385	COG2823	Periplasmic or secreted lipoprotein
NO935_RS04390	COG4251	negative regulation of phosphorylation
NO935_RS04395	COG0784	Response regulator, receiver
NO935_RS04400	COG4191	Histidine kinase
NO935_RS04405	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NO935_RS04455	COG3250	beta-galactosidase activity
NO935_RS04470	COG2188	Transcriptional regulator
NO935_RS04480	COG1609	Transcriptional regulator
NO935_RS04485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NO935_RS04490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NO935_RS04500	COG1215	transferase activity, transferring glycosyl groups
NO935_RS04505	COG0726	polysaccharide deacetylase
NO935_RS04505	COG1649	PFAM Uncharacterised BCR, COG1649
NO935_RS04540	COG3039	Transposase
NO935_RS04585	COG3039	Transposase
NO935_RS04590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NO935_RS04600	COG3039	Transposase
NO935_RS04635	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NO935_RS04675	COG2205	protein histidine kinase activity
NO935_RS04705	COG3791	Glutathione-dependent formaldehyde-activating
NO935_RS04730	COG0488	(ABC) transporter
NO935_RS04750	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NO935_RS04770	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NO935_RS04770	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NO935_RS04790	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NO935_RS04795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NO935_RS04800	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NO935_RS04820	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NO935_RS04825	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NO935_RS04835	COG2205	protein histidine kinase activity
NO935_RS04840	COG0745	RESPONSE REGULATOR receiver
NO935_RS04845	COG0277	FAD linked oxidase domain protein
NO935_RS04850	COG1988	membrane-bound metal-dependent
NO935_RS04855	COG0792	nuclease activity
NO935_RS04890	COG0275	rRNA processing
NO935_RS04895	COG3116	cell division
NO935_RS04910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NO935_RS04915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NO935_RS04930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NO935_RS04935	COG1181	Belongs to the D-alanine--D-alanine ligase family
NO935_RS04940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NO935_RS04955	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NO935_RS04965	COG1388	LysM domain
NO935_RS04965	COG4942	peptidase
NO935_RS04980	COG0494	nUDIX hydrolase
NO935_RS05000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NO935_RS05010	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_RS05010	COG3321	synthase
NO935_RS05010	COG0604	alcohol dehydrogenase
NO935_RS05055	COG2226	methyltransferase
NO935_RS05060	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NO935_RS05100	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NO935_RS05115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NO935_RS05125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NO935_RS05130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NO935_RS05140	COG0667	Aldo Keto reductase
NO935_RS05180	COG1116	anion transmembrane transporter activity
NO935_RS05185	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NO935_RS05195	COG2175	clavaminate synthase activity
NO935_RS05205	COG4181	ATPase activity
NO935_RS05220	COG0642	Histidine kinase
NO935_RS05240	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NO935_RS05260	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NO935_RS05285	COG2967	ApaG domain
NO935_RS05290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NO935_RS05300	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NO935_RS05315	COG0123	including yeast histone deacetylase and acetoin utilization protein
NO935_RS05320	COG2096	Adenosyltransferase
NO935_RS05330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NO935_RS05335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NO935_RS05375	COG0583	DNA-binding transcription factor activity
NO935_RS05380	COG0318	PFAM AMP-dependent synthetase and ligase
NO935_RS05390	COG1024	Enoyl-CoA hydratase
NO935_RS05410	COG3386	PFAM SMP-30 Gluconolaconase
NO935_RS05520	COG2197	response regulator
NO935_RS05550	COG0386	Belongs to the glutathione peroxidase family
NO935_RS05565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NO935_RS05570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NO935_RS05575	COG0583	DNA-binding transcription factor activity
NO935_RS05580	COG3634	alkyl hydroperoxide reductase activity
NO935_RS05590	COG2890	protein-(glutamine-N5) methyltransferase activity
NO935_RS05630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NO935_RS05630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NO935_RS05645	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NO935_RS05670	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NO935_RS05695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NO935_RS05705	COG1404	Belongs to the peptidase S8 family
NO935_RS05710	COG1404	Belongs to the peptidase S8 family
NO935_RS05715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NO935_RS05745	COG1295	ribonuclease BN
NO935_RS05750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NO935_RS05770	COG0521	Mo-molybdopterin cofactor biosynthetic process
NO935_RS05780	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NO935_RS05785	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NO935_RS05795	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NO935_RS05810	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NO935_RS05820	COG0193	aminoacyl-tRNA hydrolase activity
NO935_RS05825	COG0012	GTP binding
NO935_RS05855	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NO935_RS05860	COG0250	Participates in transcription elongation, termination and antitermination
NO935_RS05865	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NO935_RS05875	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NO935_RS05880	COG0222	ribosome binding
NO935_RS05885	COG0085	RNA polymerase activity
NO935_RS05890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NO935_RS05895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NO935_RS05900	COG0049	tRNA binding
NO935_RS05920	COG0051	transcription antitermination factor activity, RNA binding
NO935_RS05925	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NO935_RS05930	COG0088	Forms part of the polypeptide exit tunnel
NO935_RS05935	COG0089	rRNA binding
NO935_RS05950	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NO935_RS05960	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NO935_RS05965	COG0255	Belongs to the universal ribosomal protein uL29 family
NO935_RS05970	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NO935_RS05975	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NO935_RS05985	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NO935_RS06015	COG1841	ribosomal large subunit assembly
NO935_RS06025	COG0201	protein transport
NO935_RS06035	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NO935_RS06040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NO935_RS06050	COG0203	ribosomal protein L17
NO935_RS06110	COG3551	Protein conserved in bacteria
NO935_RS06140	COG2194	sulfuric ester hydrolase activity
NO935_RS06150	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NO935_RS06155	COG0745	RESPONSE REGULATOR receiver
NO935_RS06160	COG0642	Histidine kinase
NO935_RS06170	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NO935_RS06175	COG2894	cell division
NO935_RS06195	COG4585	Histidine kinase
NO935_RS06200	COG2197	response regulator
NO935_RS06215	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NO935_RS06240	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NO935_RS06315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NO935_RS06325	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NO935_RS06350	COG3039	Transposase
NO935_RS06365	COG3039	Transposase
NO935_RS06380	COG3039	Transposase
NO935_RS06410	COG1741	Belongs to the pirin family
NO935_RS06420	COG1515	deoxyribonuclease V activity
NO935_RS06425	COG0588	phosphoglycerate mutase activity
NO935_RS06440	COG3590	peptidase
NO935_RS06455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NO935_RS06460	COG2199	diguanylate cyclase activity
NO935_RS06460	COG2200	EAL domain
NO935_RS06460	COG2202	Pas domain
NO935_RS06465	COG0835	chemotaxis
NO935_RS06470	COG0840	transmembrane signaling receptor activity
NO935_RS06475	COG0643	Histidine kinase
NO935_RS06475	COG2198	Histidine kinase
NO935_RS06490	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NO935_RS06500	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NO935_RS06540	COG3039	Transposase
NO935_RS06600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NO935_RS06605	COG0735	belongs to the Fur family
NO935_RS06665	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NO935_RS06670	COG0084	hydrolase, TatD family'
NO935_RS06685	COG1960	acyl-CoA dehydrogenase activity
NO935_RS06700	COG0367	asparagine synthase
NO935_RS06710	COG0305	Participates in initiation and elongation during chromosome replication
NO935_RS06715	COG0415	Belongs to the DNA photolyase family
NO935_RS06845	COG5001	Diguanylate cyclase
NO935_RS06845	COG5002	protein histidine kinase activity
NO935_RS06850	COG1187	pseudouridine synthase activity
NO935_RS06870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NO935_RS06880	COG0475	glutathione-regulated potassium exporter activity
NO935_RS06885	COG5000	phosphorelay sensor kinase activity
NO935_RS06885	COG5002	protein histidine kinase activity
NO935_RS06890	COG0745	RESPONSE REGULATOR receiver
NO935_RS06920	COG1132	(ABC) transporter
NO935_RS06950	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NO935_RS06960	COG4969	Belongs to the N-Me-Phe pilin family
NO935_RS06965	COG2194	sulfuric ester hydrolase activity
NO935_RS06985	COG2184	nucleotidyltransferase activity
NO935_RS07010	COG0045	succinate-CoA ligase (ADP-forming) activity
NO935_RS07015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NO935_RS07025	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NO935_RS07025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NO935_RS07030	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NO935_RS07035	COG0564	pseudouridine synthase activity
NO935_RS07060	COG3387	PFAM Glycoside hydrolase 15-related
NO935_RS07065	COG1877	trehalose-phosphatase activity
NO935_RS07105	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NO935_RS07130	COG1946	Acyl-CoA thioesterase
NO935_RS07145	COG0824	Thioesterase
NO935_RS07150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NO935_RS07160	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NO935_RS07165	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NO935_RS07170	COG0268	Binds directly to 16S ribosomal RNA
NO935_RS07175	COG0728	peptidoglycan biosynthetic process
NO935_RS07180	COG0196	riboflavin kinase activity
NO935_RS07190	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NO935_RS07195	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NO935_RS07210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NO935_RS07215	COG1845	cytochrome c oxidase, subunit III
NO935_RS07220	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NO935_RS07245	COG3209	COG3209 Rhs family protein
NO935_RS07260	COG3328	transposase activity
NO935_RS07280	COG3209	COG3209 Rhs family protein
NO935_RS07280	COG3209	COG3209 Rhs family protein
NO935_RS07305	COG3039	Transposase
NO935_RS07420	COG0632	four-way junction helicase activity
NO935_RS07430	COG2255	four-way junction helicase activity
NO935_RS07435	COG0824	Thioesterase
NO935_RS07445	COG0848	biopolymer transport protein
NO935_RS07460	COG2885	chlorophyll binding
NO935_RS07470	COG0602	queuosine metabolic process
NO935_RS07500	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NO935_RS07525	COG0514	ATP-dependent DNA helicase (RecQ)
NO935_RS07530	COG0783	Belongs to the Dps family
NO935_RS07535	COG1643	Atp-dependent helicase
NO935_RS07560	COG0535	radical SAM domain protein
NO935_RS07565	COG0535	radical SAM domain protein
NO935_RS07585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NO935_RS07595	COG1215	transferase activity, transferring glycosyl groups
NO935_RS07600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NO935_RS07610	COG1199	ATP-dependent helicase activity
NO935_RS07630	COG0189	ligase activity
NO935_RS07645	COG0835	chemotaxis
NO935_RS07650	COG0840	transmembrane signaling receptor activity
NO935_RS07655	COG0643	Histidine kinase
NO935_RS07655	COG2198	Histidine kinase
NO935_RS07655	COG0784	Response regulator, receiver
NO935_RS07685	COG2304	oxidoreductase activity
NO935_RS07690	COG2304	oxidoreductase activity
NO935_RS07700	COG1446	asparaginase
NO935_RS07745	COG3537	Alpha-1,2-mannosidase
NO935_RS07825	COG1472	Belongs to the glycosyl hydrolase 3 family
NO935_RS07835	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NO935_RS07845	COG3858	chitin binding
NO935_RS07845	COG1388	LysM domain
NO935_RS07860	COG0837	glucose binding
NO935_RS07865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NO935_RS07875	COG0494	nUDIX hydrolase
NO935_RS07885	COG3956	TIGRFAM MazG family protein
NO935_RS07900	COG0330	HflC and HflK could
NO935_RS07915	COG0509	glycine decarboxylation via glycine cleavage system
NO935_RS07945	COG1960	acyl-CoA dehydrogenase activity
NO935_RS07955	COG1309	transcriptional regulator
NO935_RS07960	COG4771	TonB-dependent receptor
NO935_RS07970	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NO935_RS07980	COG0463	Glycosyl transferase, family 2
NO935_RS08005	COG1272	protein, Hemolysin III
NO935_RS08015	COG0739	heme binding
NO935_RS08020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NO935_RS08025	COG0626	cystathionine gamma-synthase activity
NO935_RS08035	COG1760	l-serine dehydratase
NO935_RS08050	COG2353	YceI-like domain
NO935_RS08060	COG2353	YceI-like domain
NO935_RS08130	COG1960	acyl-CoA dehydrogenase activity
NO935_RS08135	COG1024	Enoyl-CoA hydratase
NO935_RS08155	COG1024	Enoyl-CoA hydratase
NO935_RS08155	COG1250	3-hydroxyacyl-CoA dehydrogenase
NO935_RS08170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NO935_RS08200	COG1381	Involved in DNA repair and RecF pathway recombination
NO935_RS08215	COG2954	triphosphatase activity
NO935_RS08235	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
NO935_RS08240	COG3046	protein related to deoxyribodipyrimidine photolyase
NO935_RS08250	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NO935_RS08255	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NO935_RS08260	COG1278	Cold shock
NO935_RS08285	COG1201	RNA secondary structure unwinding
NO935_RS08290	COG1793	dna ligase
NO935_RS08300	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NO935_RS08300	COG1793	dna ligase
NO935_RS08330	COG0183	Belongs to the thiolase family
NO935_RS08350	COG1451	nucleotide metabolic process
NO935_RS08365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NO935_RS08375	COG3039	Transposase
NO935_RS08410	COG1047	Peptidyl-prolyl cis-trans
NO935_RS08430	COG2824	Alkylphosphonate utilization operon protein PhnA
NO935_RS08440	COG1902	pentaerythritol trinitrate reductase activity
NO935_RS08445	COG2814	Major facilitator Superfamily
NO935_RS08480	COG0392	lysyltransferase activity
NO935_RS08480	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NO935_RS08490	COG0251	oxidation-reduction process
NO935_RS08495	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NO935_RS08510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NO935_RS08535	COG1595	DNA-templated transcription, initiation
NO935_RS08550	COG2878	Part of a membrane complex involved in electron transport
NO935_RS08560	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NO935_RS08560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NO935_RS08580	COG0833	amino acid
NO935_RS08585	COG2040	homocysteine
NO935_RS08605	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NO935_RS08645	COG0529	Catalyzes the synthesis of activated sulfate
NO935_RS08645	COG2895	sulfate adenylyltransferase (ATP) activity
NO935_RS08690	COG1981	membrane
NO935_RS08720	COG4771	TonB-dependent receptor
NO935_RS08730	COG0825	malonyl-CoA metabolic process
NO935_RS08750	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NO935_RS08755	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NO935_RS08780	COG0750	zinc metalloprotease
NO935_RS08790	COG0575	Belongs to the CDS family
NO935_RS08800	COG0233	cytoplasmic translational termination
NO935_RS08815	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NO935_RS08875	COG1393	Belongs to the ArsC family
NO935_RS08885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NO935_RS08890	COG0367	asparagine synthase
NO935_RS08900	COG4774	siderophore transport
NO935_RS08925	COG2207	Transcriptional regulator
NO935_RS08940	COG1566	PFAM secretion protein HlyD family protein
NO935_RS08945	COG2814	Major facilitator Superfamily
NO935_RS08990	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NO935_RS09000	COG1960	acyl-CoA dehydrogenase activity
NO935_RS09015	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NO935_RS09025	COG2914	Belongs to the UPF0125 (RnfH) family
NO935_RS09030	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NO935_RS09040	COG0497	DNA recombination
NO935_RS09050	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NO935_RS09060	COG0484	heat shock protein binding
NO935_RS09065	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NO935_RS09070	COG0287	Prephenate dehydrogenase
NO935_RS09070	COG1605	Chorismate mutase
NO935_RS09095	COG1132	(ABC) transporter
NO935_RS09130	COG2850	peptidyl-arginine hydroxylation
NO935_RS09210	COG1131	(ABC) transporter
NO935_RS09215	COG1725	Transcriptional regulator
NO935_RS09225	COG0386	Belongs to the glutathione peroxidase family
NO935_RS09245	COG2900	Belongs to the SlyX family
NO935_RS09260	COG1609	Transcriptional regulator
NO935_RS09270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NO935_RS09280	COG1410	methionine synthase
NO935_RS09280	COG0646	methionine synthase
NO935_RS09285	COG1410	methionine synthase
NO935_RS09285	COG0646	methionine synthase
NO935_RS09290	COG2226	methyltransferase
NO935_RS09295	COG1960	acyl-CoA dehydrogenase activity
NO935_RS09320	COG0557	exoribonuclease II activity
NO935_RS09335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NO935_RS09345	COG3039	Transposase
NO935_RS09370	COG3328	transposase activity
NO935_RS09460	COG3039	Transposase
NO935_RS09470	COG0583	DNA-binding transcription factor activity
NO935_RS09530	COG3209	COG3209 Rhs family protein
NO935_RS09565	COG0643	Histidine kinase
NO935_RS09565	COG2198	Histidine kinase
NO935_RS09565	COG0784	Response regulator, receiver
NO935_RS09620	COG1684	flagellar biosynthetic protein fliR
NO935_RS09635	COG3190	flagellar
NO935_RS09685	COG1677	Flagellar hook-basal body complex protein FliE
NO935_RS09715	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_RS09725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NO935_RS09745	COG2201	protein-glutamate methylesterase activity
NO935_RS09780	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NO935_RS09785	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NO935_RS09820	COG4787	bacterial-type flagellum-dependent cell motility
NO935_RS09830	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NO935_RS09835	COG1558	bacterial-type flagellum-dependent cell motility
NO935_RS09845	COG0835	chemotaxis
NO935_RS09845	COG0784	Response regulator, receiver
NO935_RS09865	COG5002	protein histidine kinase activity
NO935_RS09875	COG4585	Histidine kinase
NO935_RS09880	COG5001	Diguanylate cyclase
NO935_RS09905	COG0482	sulfurtransferase activity
NO935_RS09920	COG0542	response to heat
NO935_RS09955	COG0492	ferredoxin-NADP+ reductase activity
NO935_RS09960	COG1674	ftsk spoiiie
NO935_RS09980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NO935_RS10000	COG0038	chloride channel
NO935_RS10005	COG0183	Belongs to the thiolase family
NO935_RS10010	COG1250	3-hydroxyacyl-CoA dehydrogenase
NO935_RS10010	COG1024	Enoyl-CoA hydratase
NO935_RS10025	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NO935_RS10035	COG1426	Protein conserved in bacteria
NO935_RS10045	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NO935_RS10055	COG0303	'Molybdopterin
NO935_RS10125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NO935_RS10135	COG3039	Transposase
NO935_RS10165	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
NO935_RS10170	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NO935_RS10180	COG0531	amino acid
NO935_RS10185	COG0531	amino acid
NO935_RS10195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NO935_RS10200	COG0277	FAD linked oxidase domain protein
NO935_RS10260	COG4133	protoheme IX ABC transporter activity
NO935_RS10265	COG0436	Aminotransferase
NO935_RS10290	COG1187	pseudouridine synthase activity
NO935_RS10295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NO935_RS10300	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NO935_RS10305	COG2350	Protein conserved in bacteria
NO935_RS10335	COG1175	transmembrane transport
NO935_RS10340	COG0395	ABC-type sugar transport system, permease component
NO935_RS10365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NO935_RS10375	COG2957	Belongs to the agmatine deiminase family
NO935_RS10390	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NO935_RS10395	COG0539	negative regulation of cytoplasmic translation
NO935_RS10400	COG0776	regulation of translation
NO935_RS10410	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NO935_RS10415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NO935_RS10425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NO935_RS10445	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NO935_RS10465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NO935_RS10470	COG0583	DNA-binding transcription factor activity
NO935_RS10485	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_RS10520	COG1914	H( )-stimulated, divalent metal cation uptake system
NO935_RS10540	COG0668	transmembrane transport
NO935_RS10580	COG3039	Transposase
NO935_RS10590	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_RS10595	COG1183	phosphatidylcholine synthase activity
NO935_RS10605	COG3243	poly(R)-hydroxyalkanoic acid synthase
NO935_RS10620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO935_RS10620	COG0723	plastoquinol--plastocyanin reductase activity
NO935_RS10630	COG2183	response to ionizing radiation
NO935_RS10645	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NO935_RS10660	COG0671	phosphoesterase, PA-phosphatase related
NO935_RS10685	COG0697	spore germination
NO935_RS10715	COG1012	belongs to the aldehyde dehydrogenase family
NO935_RS10750	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NO935_RS10765	COG0124	histidyl-tRNA synthetase
NO935_RS10795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NO935_RS10810	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NO935_RS10810	COG0131	Imidazoleglycerol-phosphate dehydratase
NO935_RS10820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NO935_RS10830	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NO935_RS10830	COG0140	phosphoribosyl-ATP diphosphatase activity
NO935_RS11000	COG2201	protein-glutamate methylesterase activity
NO935_RS11030	COG3328	transposase activity
NO935_RS11065	COG0322	excinuclease ABC activity
NO935_RS11075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NO935_RS11085	COG1663	tetraacyldisaccharide 4'-kinase activity
NO935_RS11100	COG0811	peptide transport
NO935_RS11125	COG4591	ABC-type transport system involved in lipoprotein release permease component
NO935_RS11140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NO935_RS11155	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NO935_RS11170	COG0354	folic acid binding
NO935_RS11185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NO935_RS11195	COG0363	glucosamine-6-phosphate deaminase activity
NO935_RS11200	COG0129	dihydroxy-acid dehydratase activity
NO935_RS11205	COG0800	Aldolase
NO935_RS11245	COG0784	Response regulator, receiver
NO935_RS11245	COG2205	protein histidine kinase activity
NO935_RS11245	COG5002	protein histidine kinase activity
NO935_RS11270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NO935_RS11275	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NO935_RS11280	COG0431	NADPH-dependent FMN reductase
NO935_RS11285	COG1393	Belongs to the ArsC family
NO935_RS11290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NO935_RS11310	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NO935_RS11335	COG3039	Transposase
NO935_RS11345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NO935_RS11365	COG1247	-acetyltransferase
NO935_RS11445	COG0386	Belongs to the glutathione peroxidase family
NO935_RS11530	COG3706	GGDEF domain
NO935_RS11530	COG4251	negative regulation of phosphorylation
NO935_RS11530	COG5001	Diguanylate cyclase
NO935_RS11530	COG2203	Gaf domain
NO935_RS11545	COG1472	Belongs to the glycosyl hydrolase 3 family
NO935_RS11575	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NO935_RS11580	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NO935_RS11590	COG0617	tRNA 3'-terminal CCA addition
NO935_RS11600	COG1469	GTP cyclohydrolase I activity
NO935_RS11605	COG0860	N-Acetylmuramoyl-L-alanine amidase
NO935_RS11650	COG4566	intracellular signal transduction
NO935_RS11680	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NO935_RS11685	COG0077	Prephenate dehydratase
NO935_RS11685	COG1605	Chorismate mutase
NO935_RS11695	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NO935_RS11735	COG1228	amidohydrolase
NO935_RS11740	COG2986	histidine ammonia-lyase
NO935_RS11750	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NO935_RS11775	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NO935_RS11790	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NO935_RS11810	COG3115	cell septum assembly
NO935_RS11830	COG0360	Binds together with S18 to 16S ribosomal RNA
NO935_RS11835	COG0316	Belongs to the HesB IscA family
NO935_RS11865	COG3039	Transposase
NO935_RS11875	COG0288	reversible hydration of carbon dioxide
NO935_RS11890	COG3844	kynureninase activity
NO935_RS11900	COG2925	Exonuclease
NO935_RS11910	COG0667	Aldo Keto reductase
NO935_RS11935	COG0116	Belongs to the methyltransferase superfamily
NO935_RS11935	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NO935_RS11980	COG0494	nUDIX hydrolase
NO935_RS11995	COG1024	Enoyl-CoA hydratase
NO935_RS12005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NO935_RS12040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NO935_RS12045	COG0573	inorganic phosphate transmembrane transporter activity
NO935_RS12060	COG0704	Plays a role in the regulation of phosphate uptake
NO935_RS12070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NO935_RS12105	COG3039	Transposase
NO935_RS12115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NO935_RS12120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NO935_RS12125	COG1862	Preprotein translocase
NO935_RS12130	COG0343	queuine tRNA-ribosyltransferase activity
NO935_RS12165	COG3039	Transposase
NO935_RS12215	COG0405	Gamma-glutamyltransferase
NO935_RS12220	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NO935_RS12230	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NO935_RS12235	COG0742	ribosomal rna small subunit methyltransferase
NO935_RS12265	COG1858	cytochrome C peroxidase
NO935_RS12340	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NO935_RS12345	COG4988	ABC transporter
NO935_RS12380	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NO935_RS12400	COG0165	Argininosuccinate lyase
NO935_RS12415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NO935_RS12420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NO935_RS12430	COG0137	argininosuccinate synthase activity
NO935_RS12435	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NO935_RS12450	COG2166	iron-sulfur cluster assembly
NO935_RS12480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NO935_RS12510	COG3039	Transposase
NO935_RS12530	COG4677	pectinesterase activity
NO935_RS12560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NO935_RS12565	COG0402	S-adenosylhomocysteine deaminase activity
NO935_RS12580	COG1509	lysine 2,3-aminomutase activity
NO935_RS12585	COG3300	MHYT domain
NO935_RS12585	COG5001	Diguanylate cyclase
NO935_RS12600	COG0483	inositol monophosphate 1-phosphatase activity
NO935_RS12605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NO935_RS12625	COG0488	(ABC) transporter
NO935_RS12630	COG0513	Belongs to the DEAD box helicase family
NO935_RS12635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NO935_RS12640	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NO935_RS12650	COG0625	glutathione transferase activity
NO935_RS12660	COG1671	Belongs to the UPF0178 family
NO935_RS12665	COG4681	YaeQ
NO935_RS12670	COG2081	HI0933 family
NO935_RS12680	COG0501	Belongs to the peptidase M48B family
NO935_RS12690	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_RS12710	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NO935_RS12715	COG0860	N-Acetylmuramoyl-L-alanine amidase
NO935_RS12720	COG0802	atpase or kinase
NO935_RS12725	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NO935_RS12725	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NO935_RS12730	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NO935_RS12750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NO935_RS12830	COG3039	Transposase
NO935_RS12845	COG2094	Belongs to the DNA glycosylase MPG family
NO935_RS12870	COG2969	positive regulation of protein catabolic process
NO935_RS12875	COG0625	glutathione transferase activity
NO935_RS12880	COG2857	Cytochrome c1
NO935_RS12885	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NO935_RS12890	COG0723	plastoquinol--plastocyanin reductase activity
NO935_RS12895	COG0741	lytic transglycosylase activity
NO935_RS12920	COG1702	phosphate starvation-inducible protein PhoH
NO935_RS12940	COG4535	Mg2 and Co2 transporter CorC
NO935_RS12955	COG1012	belongs to the aldehyde dehydrogenase family
NO935_RS12975	COG3842	ATPase activity
NO935_RS13010	COG0174	glutamine synthetase
NO935_RS13015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO935_RS13025	COG0477	Major facilitator Superfamily
NO935_RS13035	COG0243	molybdopterin cofactor binding
NO935_RS13045	COG2223	nitrite transmembrane transporter activity
NO935_RS13050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NO935_RS13055	COG1121	(ABC) transporter
NO935_RS13065	COG2733	membrane
NO935_RS13070	COG2205	protein histidine kinase activity
NO935_RS13070	COG5002	protein histidine kinase activity
NO935_RS13070	COG0784	Response regulator, receiver
NO935_RS13100	COG3039	Transposase
NO935_RS13105	COG2902	Dehydrogenase
NO935_RS13115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NO935_RS13120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NO935_RS13145	COG1609	Transcriptional regulator
NO935_RS13150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NO935_RS13150	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NO935_RS13155	COG1105	Belongs to the carbohydrate kinase PfkB family
NO935_RS13160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NO935_RS13160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NO935_RS13170	COG3039	Transposase
NO935_RS13185	COG3039	Transposase
NO935_RS13210	COG3039	Transposase
NO935_RS13270	COG3409	Peptidoglycan-binding domain 1 protein
NO935_RS13270	COG3501	Rhs element vgr protein
NO935_RS13310	COG3039	Transposase
NO935_RS13360	COG4771	TonB-dependent receptor
NO935_RS13370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NO935_RS13390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NO935_RS13395	COG1360	Flagellar Motor Protein
NO935_RS13400	COG1192	Involved in chromosome partitioning
NO935_RS13405	COG0835	chemotaxis
NO935_RS13415	COG0745	RESPONSE REGULATOR receiver
NO935_RS13445	COG0840	transmembrane signaling receptor activity
NO935_RS13455	COG0840	transmembrane signaling receptor activity
NO935_RS13465	COG0840	transmembrane signaling receptor activity
NO935_RS13470	COG0840	transmembrane signaling receptor activity
NO935_RS13475	COG0840	transmembrane signaling receptor activity
NO935_RS13480	COG0840	transmembrane signaling receptor activity
NO935_RS13500	COG0835	chemotaxis
NO935_RS13515	COG3039	Transposase
NO935_RS13570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NO935_RS13600	COG0318	PFAM AMP-dependent synthetase and ligase
NO935_RS13605	COG1024	Enoyl-CoA hydratase
NO935_RS13610	COG2205	protein histidine kinase activity
NO935_RS13610	COG0784	Response regulator, receiver
NO935_RS13610	COG2198	Histidine kinase
NO935_RS13675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NO935_RS13685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NO935_RS13690	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NO935_RS13700	COG0505	Belongs to the CarA family
NO935_RS13705	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NO935_RS13715	COG2258	MOSC domain
NO935_RS13720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NO935_RS13765	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NO935_RS13785	COG0477	Major facilitator Superfamily
NO935_RS13795	COG1070	Carbohydrate kinase
NO935_RS13805	COG1501	Belongs to the glycosyl hydrolase 31 family
NO935_RS13820	COG0800	Aldolase
NO935_RS13825	COG4948	Mandelate Racemase Muconate Lactonizing
NO935_RS13835	COG3734	2-keto-3-deoxy-galactonokinase
NO935_RS13840	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NO935_RS13850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NO935_RS13865	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NO935_RS13870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NO935_RS13880	COG0351	phosphomethylpyrimidine kinase
NO935_RS13905	COG0583	DNA-binding transcription factor activity
NO935_RS13910	COG1741	Belongs to the pirin family
NO935_RS13935	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NO935_RS13940	COG0305	Participates in initiation and elongation during chromosome replication
NO935_RS13960	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NO935_RS13965	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NO935_RS13970	COG2137	regulation of response to DNA damage stimulus
NO935_RS13975	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NO935_RS13985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NO935_RS13990	COG1546	Belongs to the CinA family
NO935_RS13995	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NO935_RS14005	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NO935_RS14010	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NO935_RS14020	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NO935_RS14025	COG1534	Rna-binding protein
NO935_RS14040	COG1238	metal cluster binding
NO935_RS14045	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NO935_RS14050	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NO935_RS14055	COG2840	Smr protein MutS2
NO935_RS14065	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NO935_RS14075	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NO935_RS14080	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NO935_RS14085	COG0148	phosphopyruvate hydratase activity
NO935_RS14095	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NO935_RS14100	COG0504	CTP synthase activity
NO935_RS14130	COG0306	phosphate transporter
NO935_RS14140	COG1253	flavin adenine dinucleotide binding
NO935_RS14155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NO935_RS14165	COG0477	Major facilitator Superfamily
NO935_RS14175	COG1132	(ABC) transporter
NO935_RS14180	COG1136	(ABC) transporter
NO935_RS14195	COG0438	transferase activity, transferring glycosyl groups
NO935_RS14205	COG2264	protein methyltransferase activity
NO935_RS14235	COG2244	polysaccharide biosynthetic process
NO935_RS14285	COG1595	DNA-templated transcription, initiation
NO935_RS14300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NO935_RS14320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NO935_RS14365	COG2201	protein-glutamate methylesterase activity
NO935_RS14390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NO935_RS14445	COG1858	cytochrome C peroxidase
NO935_RS14475	COG0515	serine threonine protein kinase
NO935_RS14480	COG0631	protein serine/threonine phosphatase activity
NO935_RS14580	COG3039	Transposase
NO935_RS14625	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NO935_RS14625	COG0316	Belongs to the HesB IscA family
NO935_RS14630	COG2154	pterin-4-alpha-carbinolamine dehydratase
NO935_RS14645	COG3064	Membrane
NO935_RS14655	COG1530	ribonuclease E activity
NO935_RS14670	COG1054	Belongs to the UPF0176 family
NO935_RS14690	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NO935_RS14725	COG3039	Transposase
NO935_RS14730	COG3039	Transposase
NO935_RS14765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NO935_RS14765	COG1648	precorrin-2 dehydrogenase activity
NO935_RS14790	COG0746	molybdenum cofactor guanylyltransferase activity
NO935_RS14840	COG3328	transposase activity
NO935_RS14865	COG4206	TonB-dependent receptor
NO935_RS14895	COG0531	amino acid
NO935_RS14910	COG0006	proline dipeptidase activity
NO935_RS14920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NO935_RS14935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO935_RS14940	COG3938	Belongs to the proline racemase family
NO935_RS14950	COG0552	protein localization to endoplasmic reticulum
NO935_RS14970	COG0784	Response regulator, receiver
NO935_RS14970	COG4191	Histidine kinase
NO935_RS15050	COG3040	lipid binding
NO935_RS15090	COG0438	transferase activity, transferring glycosyl groups
NO935_RS15100	COG0438	transferase activity, transferring glycosyl groups
NO935_RS15105	COG0438	transferase activity, transferring glycosyl groups
NO935_RS15175	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NO935_RS15210	COG0556	nucleotide-excision repair
NO935_RS15215	COG4969	Belongs to the N-Me-Phe pilin family
NO935_RS15255	COG1611	Belongs to the LOG family
NO935_RS15270	COG2095	MarC family integral membrane protein
NO935_RS15280	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NO935_RS15315	COG1185	polyribonucleotide nucleotidyltransferase activity
NO935_RS15320	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NO935_RS15340	COG0195	Participates in both transcription termination and antitermination
NO935_RS15345	COG0779	Required for maturation of 30S ribosomal subunits
NO935_RS15355	COG1007	ATP synthesis coupled electron transport
NO935_RS15385	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NO935_RS15390	COG1034	ATP synthesis coupled electron transport
NO935_RS15395	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NO935_RS15400	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NO935_RS15405	COG0649	NAD binding
NO935_RS15410	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NO935_RS15420	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NO935_RS15435	COG0149	triose-phosphate isomerase activity
NO935_RS15475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NO935_RS15480	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NO935_RS15485	COG0159	tryptophan synthase activity
NO935_RS15495	COG0133	tryptophan synthase activity
NO935_RS15505	COG0135	phosphoribosylanthranilate isomerase activity
NO935_RS15510	COG0101	tRNA pseudouridine synthase activity
NO935_RS15530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NO935_RS15535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NO935_RS15540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NO935_RS15545	COG2890	protein-(glutamine-N5) methyltransferase activity
NO935_RS15585	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NO935_RS15615	COG0717	Belongs to the dCTP deaminase family
NO935_RS15620	COG0489	protein tyrosine kinase activity
NO935_RS15660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO935_RS15665	COG2311	Membrane
NO935_RS15670	COG1047	Peptidyl-prolyl cis-trans
NO935_RS15675	COG0791	NLP P60 protein
NO935_RS15680	COG0791	NLP P60 protein
NO935_RS15700	COG1785	Belongs to the alkaline phosphatase family
NO935_RS15705	COG0037	tRNA processing
NO935_RS15710	COG1722	exodeoxyribonuclease VII activity
NO935_RS15715	COG0142	geranyltranstransferase activity
NO935_RS15735	COG0312	modulator of DNA gyrase
NO935_RS15740	COG3028	Belongs to the UPF0307 family
NO935_RS15745	COG0312	modulator of DNA gyrase
NO935_RS15755	COG3164	Protein of unknown function
NO935_RS15770	COG2968	Membrane
NO935_RS15800	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NO935_RS15825	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NO935_RS15850	COG3118	belongs to the thioredoxin family
NO935_RS15915	COG3039	Transposase
NO935_RS15995	COG2022	thiamine diphosphate biosynthetic process
NO935_RS16005	COG0471	metal ion transport
NO935_RS16005	COG3273	potassium ion transport
NO935_RS16035	COG1970	mechanosensitive ion channel activity
NO935_RS16055	COG2272	Belongs to the type-B carboxylesterase lipase family
NO935_RS16060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NO935_RS16080	COG0308	aminopeptidase N
NO935_RS16085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NO935_RS16095	COG0529	Catalyzes the synthesis of activated sulfate
NO935_RS16095	COG2895	sulfate adenylyltransferase (ATP) activity
NO935_RS16100	COG0175	sulfate reduction
NO935_RS16105	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NO935_RS16110	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NO935_RS16115	COG0175	sulfate reduction
NO935_RS16135	COG0784	Response regulator, receiver
NO935_RS16135	COG2198	Histidine kinase
NO935_RS16135	COG2205	protein histidine kinase activity
NO935_RS16180	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NO935_RS16185	COG3588	fructose-bisphosphate aldolase
NO935_RS16190	COG0469	pyruvate kinase activity
NO935_RS16230	COG0753	catalase activity
NO935_RS16255	COG2207	Transcriptional regulator
NO935_RS16255	COG1917	Cupin 2, conserved barrel domain protein
NO935_RS16275	COG0823	Involved in the tonB-independent uptake of proteins
NO935_RS16275	COG1506	peptidase
NO935_RS16295	COG1297	OPT oligopeptide transporter protein
NO935_RS16310	COG0587	DNA-directed DNA polymerase activity
NO935_RS16385	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NO935_RS16400	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
NO935_RS16405	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
NO935_RS16410	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NO935_RS16430	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
NO935_RS16445	COG0732	type I restriction modification DNA specificity domain
NO935_RS16450	COG3039	Transposase
NO935_RS16455	COG0732	type I restriction modification DNA specificity domain
NO935_RS16660	COG3179	chitinase
NO935_RS16730	COG1741	Belongs to the pirin family
NO935_RS16735	COG1966	Carbon starvation protein
NO935_RS16740	COG2879	small protein
NO935_RS16765	COG3039	Transposase
NO935_RS16785	COG2203	Gaf domain
NO935_RS16785	COG4251	negative regulation of phosphorylation
NO935_RS16785	COG5001	Diguanylate cyclase
NO935_RS16785	COG3706	GGDEF domain
NO935_RS16790	COG0629	single-stranded DNA binding
NO935_RS16795	COG0142	geranyltranstransferase activity
NO935_RS16820	COG0527	aspartate kinase activity
NO935_RS16830	COG0384	phenazine biosynthesis protein PhzF
NO935_RS16840	COG1764	response to oxidative stress
NO935_RS16855	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NO935_RS16860	COG1678	Uncharacterized ACR, COG1678
NO935_RS16875	COG0519	Catalyzes the synthesis of GMP from XMP
NO935_RS16905	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NO935_RS16965	COG1959	2 iron, 2 sulfur cluster binding
NO935_RS16970	COG0719	Fe-S assembly protein
NO935_RS16975	COG0396	ATPase activity
NO935_RS16980	COG0719	Fe-S assembly protein
NO935_RS16985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NO935_RS17000	COG2146	nitrite reductase [NAD(P)H] activity
NO935_RS17035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NO935_RS17050	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NO935_RS17060	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NO935_RS17065	COG0174	glutamine synthetase
NO935_RS17070	COG3328	transposase activity
NO935_RS17095	COG0326	Molecular chaperone. Has ATPase activity
NO935_RS17100	COG2207	Transcriptional regulator
NO935_RS17125	COG0657	acetylesterase activity
NO935_RS17125	COG2755	lipolytic protein G-D-S-L family
NO935_RS17150	COG0488	(ABC) transporter
NO935_RS17185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NO935_RS17185	COG4651	solute:proton antiporter activity
NO935_RS17200	COG4772	TonB-dependent receptor
NO935_RS17210	COG4264	IucA IucC family
NO935_RS17215	COG2814	Major facilitator Superfamily
NO935_RS17225	COG0019	diaminopimelate decarboxylase activity
NO935_RS17290	COG4206	TonB-dependent receptor
NO935_RS17315	COG3039	Transposase
NO935_RS17330	COG0542	response to heat
NO935_RS17380	COG0336	Belongs to the RNA methyltransferase TrmD family
NO935_RS17385	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NO935_RS17390	COG0228	four-way junction DNA binding
NO935_RS17410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NO935_RS17420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NO935_RS17465	COG1555	photosystem II stabilization
NO935_RS17470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NO935_RS17485	COG3178	'Phosphotransferase
NO935_RS17490	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NO935_RS17500	COG0628	permease
NO935_RS17510	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NO935_RS17525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NO935_RS17545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NO935_RS17550	COG0271	Belongs to the BolA IbaG family
NO935_RS17560	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NO935_RS17570	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NO935_RS17575	COG1137	ATPase activity
NO935_RS17590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NO935_RS17595	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NO935_RS17600	COG1660	Displays ATPase and GTPase activities
NO935_RS17615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NO935_RS17620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NO935_RS17625	COG2239	Acts as a magnesium transporter
NO935_RS17635	COG1294	oxidase, subunit
NO935_RS17640	COG1271	oxidase subunit
NO935_RS17655	COG1113	amino acid transport
NO935_RS17670	COG2197	response regulator
NO935_RS17675	COG0531	amino acid
NO935_RS17735	COG0754	glutathionylspermidine amidase activity
NO935_RS17760	COG1842	Phage shock protein A
NO935_RS17775	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NO935_RS17790	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NO935_RS17820	COG2201	protein-glutamate methylesterase activity
NO935_RS17865	COG2201	protein-glutamate methylesterase activity
NO935_RS17885	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NO935_RS17945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NO935_RS17950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NO935_RS17980	COG3039	Transposase
NO935_RS17995	COG0745	RESPONSE REGULATOR receiver
NO935_RS18000	COG2205	protein histidine kinase activity
NO935_RS18020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NO935_RS18050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NO935_RS18050	COG3453	Protein conserved in bacteria
NO935_RS18055	COG0725	ABC transporter, periplasmic molybdate-binding protein
NO935_RS18060	COG4149	molybdate abc transporter
NO935_RS18065	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NO935_RS18085	COG0642	Histidine kinase
NO935_RS18100	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_RS18115	COG1022	Amp-dependent synthetase and ligase
NO935_RS18140	COG1376	ErfK ybiS ycfS ynhG family protein
NO935_RS18145	COG0739	heme binding
NO935_RS18155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NO935_RS18160	COG1301	dicarboxylic acid transport
NO935_RS18180	COG2304	oxidoreductase activity
NO935_RS18200	COG0714	Associated with various cellular activities
NO935_RS18240	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NO935_RS18265	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NO935_RS18275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NO935_RS18300	COG1561	YicC-like family, N-terminal region
NO935_RS18305	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NO935_RS18320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NO935_RS18355	COG0006	proline dipeptidase activity
NO935_RS18380	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NO935_RS18390	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NO935_RS18400	COG2912	Transglutaminase-like superfamily
NO935_RS18405	COG1773	rubredoxin
NO935_RS18410	COG0352	thiamine-phosphate diphosphorylase activity
NO935_RS18435	COG0281	malic enzyme
NO935_RS18435	COG0280	phosphate acetyltransferase
NO935_RS18455	COG4191	Histidine kinase
NO935_RS18470	COG0583	DNA-binding transcription factor activity
NO935_RS18490	COG2197	response regulator
NO935_RS18500	COG0642	Histidine kinase
NO935_RS18515	COG2851	Citrate transporter
NO935_RS18520	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_RS18525	COG1609	Transcriptional regulator
NO935_RS18535	COG2211	Major facilitator Superfamily
NO935_RS18560	COG1162	GTPase activity
NO935_RS18585	COG0726	polysaccharide deacetylase
NO935_RS18590	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NO935_RS18650	COG0242	peptide deformylase activity
NO935_RS18670	COG0714	Associated with various cellular activities
NO935_RS18690	COG0537	adenosine 5'-monophosphoramidase activity
NO935_RS18720	COG0314	molybdopterin synthase activity
NO935_RS18725	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NO935_RS18730	COG0315	cyclic pyranopterin monophosphate synthase activity
NO935_RS18740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NO935_RS18745	COG1234	tRNA 3'-trailer cleavage
NO935_RS18750	COG3642	lipopolysaccharide core region biosynthetic process
NO935_RS18755	COG0859	PFAM glycosyl transferase family 9
NO935_RS18765	COG0582	viral genome integration into host DNA
NO935_RS18825	COG0631	protein serine/threonine phosphatase activity
NO935_RS18860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NO935_RS18900	COG0544	peptidyl-prolyl cis-trans isomerase activity
NO935_RS18950	COG0473	3-isopropylmalate dehydrogenase activity
NO935_RS18975	COG4783	chaperone-mediated protein folding
NO935_RS18990	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NO935_RS19000	COG0438	transferase activity, transferring glycosyl groups
NO935_RS19005	COG0671	phosphoesterase, PA-phosphatase related
NO935_RS19010	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NO935_RS19035	COG2833	Protein of unknown function (DUF455)
NO935_RS19055	COG0285	dihydrofolate synthase activity
NO935_RS19065	COG0406	alpha-ribazole phosphatase activity
NO935_RS19095	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NO935_RS19100	COG4208	sulfate ABC transporter
NO935_RS19105	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NO935_RS19110	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NO935_RS19115	COG0156	8-amino-7-oxononanoate synthase activity
NO935_RS19140	COG0604	alcohol dehydrogenase
NO935_RS19145	COG1902	pentaerythritol trinitrate reductase activity
NO935_RS19145	COG0446	pyridine nucleotide-disulphide oxidoreductase
NO935_RS19180	COG0584	glycerophosphoryl diester phosphodiesterase
NO935_RS19205	COG3039	Transposase
NO935_RS19220	COG0625	glutathione transferase activity
NO935_RS19225	COG0039	L-malate dehydrogenase activity
NO935_RS19230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NO935_RS19235	COG1217	gtp-binding protein TYPA
NO935_RS19255	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NO935_RS19400	COG3781	membrane
NO935_RS19410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NO935_RS19440	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NO935_RS19450	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NO935_RS19475	COG3710	Transcriptional regulator
NO935_RS19480	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NO935_RS19490	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NO935_RS19525	COG0066	3-isopropylmalate dehydratase activity
NO935_RS19530	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NO935_RS19560	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NO935_RS19565	COG1538	Outer membrane efflux protein
NO935_RS19570	COG1519	Transferase
NO935_RS19575	COG1560	Kdo2-lipid A biosynthetic process
NO935_RS19625	COG0308	aminopeptidase N
NO935_RS19630	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NO935_RS19640	COG0330	HflC and HflK could
NO935_RS19645	COG0330	HflC and HflK could
NO935_RS19665	COG0678	peroxiredoxin activity
NO935_RS19675	COG2826	transposase and inactivated derivatives, IS30 family
NO935_RS19770	COG3829	transcription factor binding
NO935_RS19805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NO935_RS19810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NO935_RS19820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO935_RS19825	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_RS19850	COG1399	metal-binding, possibly nucleic acid-binding protein
NO935_RS19890	COG1518	maintenance of DNA repeat elements
NO935_RS19895	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NO935_RS19940	COG2188	Transcriptional regulator
NO935_RS19955	COG1450	Type ii and iii secretion system protein
NO935_RS19970	COG3166	PFAM Fimbrial assembly family protein
NO935_RS19975	COG3156	type II secretion system protein K
NO935_RS19980	COG4795	General secretion pathway protein
NO935_RS19985	COG2165	general secretion pathway protein
NO935_RS19990	COG4970	Tfp pilus assembly protein FimT
NO935_RS19995	COG2165	general secretion pathway protein
NO935_RS20000	COG1459	type II secretion system
NO935_RS20010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NO935_RS20020	COG5295	Hep Hag repeat protein
NO935_RS20025	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NO935_RS20025	COG0047	phosphoribosylformylglycinamidine synthase activity
NO935_RS20030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NO935_RS20035	COG4974	Belongs to the 'phage' integrase family
NO935_RS20050	COG0795	lipopolysaccharide-transporting ATPase activity
NO935_RS20060	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NO935_RS20075	COG0525	valine-tRNA ligase activity
NO935_RS20105	COG3039	Transposase
NO935_RS20130	COG3039	Transposase
NO935_RS20160	COG1183	phosphatidylcholine synthase activity
NO935_RS20170	COG0442	prolyl-tRNA aminoacylation
NO935_RS20185	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NO935_RS20190	COG1127	ABC transporter
NO935_RS20195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NO935_RS20195	COG3218	ABC-type transport auxiliary lipoprotein component
NO935_RS20230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NO935_RS20235	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NO935_RS20235	COG0662	Cupin 2, conserved barrel domain protein
NO935_RS20260	COG2086	electron transfer activity
NO935_RS20285	COG3328	transposase activity
NO935_RS20325	COG0626	cystathionine gamma-synthase activity
NO935_RS20355	COG0625	glutathione transferase activity
NO935_RS20365	COG0513	Belongs to the DEAD box helicase family
NO935_RS20370	COG0720	synthase
NO935_RS20380	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NO935_RS20385	COG1956	GAF domain-containing protein
NO935_RS20420	COG0339	signal peptide processing
NO935_RS20470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NO935_RS20475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NO935_RS20525	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NO935_RS20530	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NO935_RS20535	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NO935_RS20540	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NO935_RS20550	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NO935_RS20560	COG0356	it plays a direct role in the translocation of protons across the membrane
NO935_RS20580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NO935_RS20590	COG0508	dehydrogenase complex catalyzes the overall conversion of
NO935_RS20620	COG2011	ABC-type metal ion transport system permease component
NO935_RS20630	COG0697	spore germination
NO935_RS20665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NO935_RS20670	COG1187	pseudouridine synthase activity
NO935_RS20675	COG2813	Specifically methylates the guanine in position
NO935_RS20705	COG2205	protein histidine kinase activity
NO935_RS20705	COG2202	Pas domain
NO935_RS20730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO935_RS20780	COG0745	RESPONSE REGULATOR receiver
NO935_RS20795	COG1404	Belongs to the peptidase S8 family
NO935_RS20815	COG0842	Transport permease protein
NO935_RS20820	COG1131	(ABC) transporter
NO935_RS20825	COG0025	NhaP-type Na H and K H
NO935_RS20835	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NO935_RS20845	COG1573	uracil-dna glycosylase
NO935_RS20855	COG3384	dioxygenase
NO935_RS20870	COG0667	Aldo Keto reductase
NO935_RS20880	COG3590	peptidase
NO935_RS20900	COG0531	amino acid
NO935_RS20975	COG1271	oxidase subunit
NO935_RS20980	COG1294	oxidase, subunit
NO935_RS21010	COG1324	tolerance protein
NO935_RS21020	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NO935_RS21025	COG0511	ligase activity, forming carbon-carbon bonds
NO935_RS21035	COG0439	Biotin carboxylase
NO935_RS21075	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NO935_RS21125	COG3039	Transposase
NO935_RS21145	COG3039	Transposase
NO935_RS21175	COG3210	domain, Protein
NO935_RS21180	COG2831	hemolysin activation secretion protein
NO935_RS21220	COG0138	bifunctional purine biosynthesis protein purh
NO935_RS21230	COG0151	Belongs to the GarS family
NO935_RS21235	COG0577	efflux transmembrane transporter activity
NO935_RS21235	COG1136	(ABC) transporter
NO935_RS21245	COG1289	transmembrane transporter activity
NO935_RS21260	COG2814	Major facilitator Superfamily
NO935_RS21275	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NO935_RS21310	COG0745	RESPONSE REGULATOR receiver
NO935_RS21355	COG0739	heme binding
NO935_RS21370	COG2211	Major facilitator Superfamily
NO935_RS21375	COG0708	Exodeoxyribonuclease III
NO935_RS21390	COG1192	Involved in chromosome partitioning
NO935_RS21395	COG1475	DNA binding
NO935_RS21410	COG0463	Glycosyl transferase, family 2
NO935_RS21430	COG0756	dUTP diphosphatase activity
NO935_RS21435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NO935_RS21440	COG2003	Belongs to the UPF0758 family
NO935_RS21445	COG0018	arginyl-trna synthetase
NO935_RS21460	COG4221	oxidoreductase activity
NO935_RS21485	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NO935_RS21490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NO935_RS21510	COG3485	protocatechuate 3,4-dioxygenase
NO935_RS21550	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NO935_RS21555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NO935_RS21565	COG0045	succinate-CoA ligase (ADP-forming) activity
NO935_RS21565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NO935_RS21565	COG1042	CoA-binding domain protein
NO935_RS21575	COG2239	Acts as a magnesium transporter
NO935_RS21590	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NO935_RS21595	COG3387	PFAM Glycoside hydrolase 15-related
NO935_RS21610	COG3100	YcgL domain-containing protein
NO935_RS21615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NO935_RS21625	COG0463	Glycosyl transferase, family 2
NO935_RS21640	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_RS21650	COG0156	8-amino-7-oxononanoate synthase activity
NO935_RS21655	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NO935_RS21660	COG1040	competence protein
NO935_RS21665	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NO935_RS21675	COG0628	permease
NO935_RS21685	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NO935_RS21695	COG1595	DNA-templated transcription, initiation
NO935_RS21700	COG0753	catalase activity
NO935_RS21745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NO935_RS21750	COG0180	Tryptophanyl-tRNA synthetase
NO935_RS21755	COG3237	CsbD-like
NO935_RS21790	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NO935_RS21810	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NO935_RS21815	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NO935_RS21815	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NO935_RS21860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NO935_RS21900	COG1199	ATP-dependent helicase activity
NO935_RS21940	COG0583	DNA-binding transcription factor activity
NO935_RS21985	COG0625	glutathione transferase activity
NO935_RS22020	COG4555	ABC transporter
NO935_RS22030	COG1476	TRANSCRIPTIONal
NO935_RS22055	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NO935_RS22060	COG1131	(ABC) transporter
NO935_RS22065	COG0842	Transport permease protein
NO935_RS22075	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NO935_RS22140	COG1181	Belongs to the D-alanine--D-alanine ligase family
NO935_RS22150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NO935_RS22160	COG0564	pseudouridine synthase activity
NO935_RS22190	COG0339	signal peptide processing
NO935_RS22220	COG3254	rhamnose metabolic process
NO935_RS22225	COG0738	Major facilitator superfamily
NO935_RS22230	COG1414	Transcriptional regulator
NO935_RS22245	COG2205	protein histidine kinase activity
NO935_RS22255	COG3459	Glycosyltransferase 36 associated
NO935_RS22260	COG2211	Major facilitator Superfamily
NO935_RS22265	COG3265	gluconokinase activity
NO935_RS22270	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NO935_RS22345	COG1127	ABC transporter
NO935_RS22350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NO935_RS22355	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NO935_RS22370	COG2853	Lipoprotein
NO935_RS22390	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NO935_RS22455	COG0676	glucose-6-phosphate 1-epimerase activity
NO935_RS22480	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NO935_RS22490	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NO935_RS22500	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NO935_RS22505	COG1064	alcohol dehydrogenase
NO935_RS22545	COG1522	sequence-specific DNA binding
NO935_RS22550	COG3186	Phenylalanine-4-hydroxylase
NO935_RS22590	COG0656	L-ascorbic acid biosynthetic process
NO935_RS22595	COG2130	NADP-dependent
NO935_RS22600	COG0667	Aldo Keto reductase
NO935_RS22610	COG1187	pseudouridine synthase activity
NO935_RS22620	COG1643	Atp-dependent helicase
NO935_RS22625	COG4807	Protein conserved in bacteria
NO935_RS22630	COG4948	Mandelate Racemase Muconate Lactonizing
NO935_RS22635	COG0179	Fumarylacetoacetate (FAA) hydrolase
NO935_RS22640	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_RS22700	COG3162	membrane
NO935_RS22705	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NO935_RS22720	COG0708	Exodeoxyribonuclease III
NO935_RS22730	COG3039	Transposase
NO935_RS22740	COG2091	lysine biosynthetic process via aminoadipic acid
NO935_RS22750	COG3540	Alkaline phosphatase
NO935_RS22755	COG0357	Ribosomal RNA small subunit methyltransferase G
NO935_RS22775	COG2159	amidohydrolase
NO935_RS22785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NO935_RS22790	COG0583	DNA-binding transcription factor activity
NO935_RS22795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NO935_RS22810	COG0210	DNA helicase
NO935_RS22825	COG0531	amino acid
NO935_RS22835	COG1322	Protein conserved in bacteria
NO935_RS22845	COG0386	Belongs to the glutathione peroxidase family
NO935_RS22895	COG0793	Belongs to the peptidase S41A family
NO935_RS22900	COG4942	peptidase
NO935_RS22910	COG2234	aminopeptidase activity
NO935_RS22955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NO935_RS22960	COG0302	gtp cyclohydrolase
NO935_RS22980	COG0477	Major facilitator Superfamily
NO935_RS23065	COG1192	Involved in chromosome partitioning
NO935_RS23095	COG1929	Belongs to the glycerate kinase type-1 family
NO935_RS23100	COG2271	Major facilitator Superfamily
NO935_RS23115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NO935_RS23120	COG0861	Integral membrane protein TerC family
NO935_RS23130	COG0584	glycerophosphoryl diester phosphodiesterase
NO935_RS23140	COG0671	phosphoesterase, PA-phosphatase related
NO935_RS23150	COG0726	polysaccharide deacetylase
NO935_RS23190	COG4720	Psort location CytoplasmicMembrane, score
NO935_RS23205	COG0110	maltose O-acetyltransferase activity
NO935_RS23215	COG0308	aminopeptidase N
NO935_RS23240	COG2186	Transcriptional regulator
NO935_RS23270	COG2814	Major facilitator Superfamily
NO935_RS23275	COG2814	Major facilitator Superfamily
NO935_RS23350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NO935_RS23375	COG4974	Belongs to the 'phage' integrase family
NO935_RS23640	COG1061	Type III restriction enzyme res subunit
NO935_RS23700	COG0582	viral genome integration into host DNA
NO935_RS23710	COG2261	transglycosylase associated protein
NO935_RS23725	COG0446	pyridine nucleotide-disulphide oxidoreductase
NO935_RS23730	COG2826	transposase and inactivated derivatives, IS30 family
NO935_RS23770	COG1192	Involved in chromosome partitioning
NO935_RS23785	COG1278	Cold shock
NO935_RS23815	COG0577	efflux transmembrane transporter activity
NO935_RS23815	COG1136	(ABC) transporter
NO935_RS23825	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NO935_RS23850	COG1192	Involved in chromosome partitioning
NO935_RS23860	COG2189	Belongs to the N(4) N(6)-methyltransferase family
NO935_RS23865	COG3421	Type III restriction