locus-tag	class	description
XOC_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XOC_RS00020	COG0187	DNA topoisomerase II activity
XOC_RS00030	COG0501	Belongs to the peptidase M48B family
XOC_RS00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XOC_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XOC_RS00140	COG2801	Transposase and inactivated derivatives
XOC_RS00210	COG1064	alcohol dehydrogenase
XOC_RS00215	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XOC_RS00220	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XOC_RS00225	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XOC_RS00235	COG2234	aminopeptidase activity
XOC_RS00245	COG4942	peptidase
XOC_RS00250	COG0793	Belongs to the peptidase S41A family
XOC_RS00255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XOC_RS00300	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XOC_RS00310	COG3039	Transposase
XOC_RS00320	COG3039	Transposase
XOC_RS00325	COG1304	FMN binding
XOC_RS00335	COG1657	PFAM Prenyltransferase squalene oxidase
XOC_RS00340	COG0142	geranyltranstransferase activity
XOC_RS00345	COG2124	cytochrome p450
XOC_RS00350	COG1028	Short-chain dehydrogenase reductase Sdr
XOC_RS00355	COG1141	Ferredoxin
XOC_RS00360	COG2124	cytochrome p450
XOC_RS00365	COG2124	cytochrome p450
XOC_RS00450	COG3549	Plasmid maintenance system killer
XOC_RS00455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XOC_RS00460	COG1074	ATP-dependent DNA helicase activity
XOC_RS00465	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XOC_RS00490	COG1127	ABC transporter
XOC_RS00495	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XOC_RS00500	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XOC_RS00515	COG2853	Lipoprotein
XOC_RS00520	COG0386	Belongs to the glutathione peroxidase family
XOC_RS00530	COG1322	Protein conserved in bacteria
XOC_RS00540	COG0531	amino acid
XOC_RS00570	COG2826	transposase and inactivated derivatives, IS30 family
XOC_RS00580	COG0493	'glutamate synthase
XOC_RS00585	COG0070	glutamate synthase
XOC_RS00585	COG0069	glutamate synthase activity
XOC_RS00585	COG0067	glutamate synthase
XOC_RS00635	COG1111	helicase
XOC_RS00635	COG1205	dead DEAH box helicase
XOC_RS00640	COG1272	protein, Hemolysin III
XOC_RS00660	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XOC_RS00670	COG4772	TonB-dependent receptor
XOC_RS00680	COG3039	Transposase
XOC_RS00685	COG1304	FMN binding
XOC_RS00690	COG1755	Isoprenylcysteine carboxyl methyltransferase
XOC_RS00715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XOC_RS00725	COG3039	Transposase
XOC_RS00745	COG0477	Major facilitator Superfamily
XOC_RS00795	COG3237	CsbD-like
XOC_RS00820	COG3039	Transposase
XOC_RS00845	COG0477	Major facilitator Superfamily
XOC_RS00870	COG0302	gtp cyclohydrolase
XOC_RS00905	COG0730	response to heat
XOC_RS00920	COG0676	glucose-6-phosphate 1-epimerase activity
XOC_RS00940	COG3135	benzoate transporter
XOC_RS00975	COG2963	transposase activity
XOC_RS01010	COG3039	Transposase
XOC_RS01025	COG0366	Alpha amylase catalytic
XOC_RS01030	COG0366	Alpha amylase catalytic
XOC_RS01050	COG1609	Transcriptional regulator
XOC_RS01060	COG1028	Short-chain dehydrogenase reductase Sdr
XOC_RS01070	COG3186	Phenylalanine-4-hydroxylase
XOC_RS01075	COG1522	sequence-specific DNA binding
XOC_RS01080	COG4773	Receptor
XOC_RS01085	COG1752	Esterase of the alpha-beta hydrolase superfamily
XOC_RS01090	COG1473	amidohydrolase
XOC_RS01100	COG1119	ATPase activity
XOC_RS01115	COG0517	IMP dehydrogenase activity
XOC_RS01115	COG1125	glycine betaine transport
XOC_RS01130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XOC_RS01135	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XOC_RS01140	COG3550	peptidyl-serine autophosphorylation
XOC_RS01145	COG1396	sequence-specific DNA binding
XOC_RS01165	COG0489	protein tyrosine kinase activity
XOC_RS01170	COG2062	phosphohistidine phosphatase, SixA
XOC_RS01180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XOC_RS01225	COG1968	undecaprenyl-diphosphatase activity
XOC_RS01230	COG0174	glutamine synthetase
XOC_RS01235	COG0347	Belongs to the P(II) protein family
XOC_RS01240	COG0004	ammonium transporteR
XOC_RS01245	COG3852	Histidine kinase
XOC_RS01250	COG2204	response regulator
XOC_RS01255	COG2032	superoxide dismutase activity
XOC_RS01260	COG2032	superoxide dismutase activity
XOC_RS01275	COG3039	Transposase
XOC_RS01300	COG0183	Belongs to the thiolase family
XOC_RS01340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XOC_RS01345	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XOC_RS01360	COG0028	Belongs to the TPP enzyme family
XOC_RS01365	COG2205	protein histidine kinase activity
XOC_RS01390	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XOC_RS01405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XOC_RS01410	COG3177	Filamentation induced by cAMP protein fic
XOC_RS01415	COG0596	Alpha beta hydrolase
XOC_RS01420	COG0727	PFAM Uncharacterised protein family (UPF0153)
XOC_RS01425	COG0318	PFAM AMP-dependent synthetase and ligase
XOC_RS01430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XOC_RS01445	COG1181	Belongs to the D-alanine--D-alanine ligase family
XOC_RS01460	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XOC_RS01475	COG0564	pseudouridine synthase activity
XOC_RS01500	COG0339	signal peptide processing
XOC_RS01520	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XOC_RS01525	COG3265	gluconokinase activity
XOC_RS01535	COG3459	Glycosyltransferase 36 associated
XOC_RS01550	COG2205	protein histidine kinase activity
XOC_RS01560	COG1414	Transcriptional regulator
XOC_RS01565	COG0738	Major facilitator superfamily
XOC_RS01595	COG3162	membrane
XOC_RS01600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XOC_RS01610	COG0708	Exodeoxyribonuclease III
XOC_RS01625	COG2091	lysine biosynthetic process via aminoadipic acid
XOC_RS01635	COG3540	Alkaline phosphatase
XOC_RS01640	COG0357	Ribosomal RNA small subunit methyltransferase G
XOC_RS01665	COG2159	amidohydrolase
XOC_RS01675	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XOC_RS01680	COG0583	DNA-binding transcription factor activity
XOC_RS01685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XOC_RS01700	COG0210	DNA helicase
XOC_RS01770	COG1028	Short-chain dehydrogenase reductase Sdr
XOC_RS01815	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XOC_RS01830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XOC_RS01870	COG0408	coproporphyrinogen oxidase activity
XOC_RS01885	COG0463	Glycosyl transferase, family 2
XOC_RS01895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XOC_RS01900	COG3100	YcgL domain-containing protein
XOC_RS01915	COG3387	PFAM Glycoside hydrolase 15-related
XOC_RS01920	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XOC_RS01925	COG3039	Transposase
XOC_RS01950	COG2239	Acts as a magnesium transporter
XOC_RS01960	COG1042	CoA-binding domain protein
XOC_RS01960	COG0045	succinate-CoA ligase (ADP-forming) activity
XOC_RS01960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XOC_RS01970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XOC_RS01975	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XOC_RS01995	COG2801	Transposase and inactivated derivatives
XOC_RS02000	COG2963	transposase activity
XOC_RS02045	COG2963	transposase activity
XOC_RS02095	COG0513	Belongs to the DEAD box helicase family
XOC_RS02105	COG3039	Transposase
XOC_RS02120	COG0508	dehydrogenase complex catalyzes the overall conversion of
XOC_RS02135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XOC_RS02145	COG3483	tryptophan 2,3-dioxygenase activity
XOC_RS02150	COG3104	oligopeptide transport
XOC_RS02180	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XOC_RS02185	COG1320	monovalent cation:proton antiporter activity
XOC_RS02190	COG2212	antiporter activity
XOC_RS02200	COG0651	ATP synthesis coupled electron transport
XOC_RS02205	COG1006	Multisubunit Na H antiporter MnhC subunit
XOC_RS02210	COG2111	Na H antiporter
XOC_RS02210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XOC_RS02250	COG0708	Exodeoxyribonuclease III
XOC_RS02255	COG2211	Major facilitator Superfamily
XOC_RS02275	COG0739	heme binding
XOC_RS02310	COG2963	transposase activity
XOC_RS02335	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XOC_RS02350	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XOC_RS02400	COG0358	DNA primase activity
XOC_RS02405	COG1295	ribonuclease BN
XOC_RS02410	COG1610	YqeY-like protein
XOC_RS02420	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XOC_RS02425	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XOC_RS02440	COG2133	pyrroloquinoline quinone binding
XOC_RS02445	COG4682	membrane
XOC_RS02460	COG0531	amino acid
XOC_RS02470	COG4948	Mandelate Racemase Muconate Lactonizing
XOC_RS02480	COG3023	N-Acetylmuramoyl-L-alanine amidase
XOC_RS02485	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XOC_RS02525	COG5383	Protein conserved in bacteria
XOC_RS02555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XOC_RS02560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XOC_RS02565	COG1473	amidohydrolase
XOC_RS02575	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XOC_RS02575	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XOC_RS02605	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XOC_RS02610	COG3118	belongs to the thioredoxin family
XOC_RS02620	COG2884	Cell division ATP-binding protein ftsE
XOC_RS02625	COG2177	Part of the ABC transporter FtsEX involved in
XOC_RS02630	COG2201	protein-glutamate methylesterase activity
XOC_RS02635	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XOC_RS02640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XOC_RS02645	COG2860	membrane
XOC_RS02650	COG1252	NADH dehydrogenase
XOC_RS02680	COG0459	protein refolding
XOC_RS02695	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XOC_RS02710	COG3386	PFAM SMP-30 Gluconolaconase
XOC_RS02715	COG2963	transposase activity
XOC_RS02730	COG4221	oxidoreductase activity
XOC_RS02775	COG0697	spore germination
XOC_RS02780	COG4305	rare lipoprotein A
XOC_RS02800	COG1113	amino acid transport
XOC_RS02810	COG0598	Magnesium transport protein CorA
XOC_RS02880	COG0659	secondary active sulfate transmembrane transporter activity
XOC_RS02905	COG3275	phosphorelay sensor kinase activity
XOC_RS02915	COG0181	hydroxymethylbilane synthase activity
XOC_RS02940	COG1505	serine-type exopeptidase activity
XOC_RS02950	COG0436	Aminotransferase
XOC_RS02960	COG2832	Protein of unknown function (DUF454)
XOC_RS02980	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XOC_RS03020	COG3300	MHYT domain
XOC_RS03020	COG5001	Diguanylate cyclase
XOC_RS03040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XOC_RS03045	COG1077	Cell shape determining protein MreB Mrl
XOC_RS03050	COG1792	Involved in formation and maintenance of cell shape
XOC_RS03065	COG0772	Belongs to the SEDS family
XOC_RS03080	COG2951	lytic endotransglycosylase activity
XOC_RS03085	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XOC_RS03095	COG1686	Belongs to the peptidase S11 family
XOC_RS03105	COG2921	Belongs to the UPF0250 family
XOC_RS03130	COG1056	cytidyltransferase-related domain
XOC_RS03130	COG1051	belongs to the nudix hydrolase family
XOC_RS03170	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XOC_RS03180	COG0673	inositol 2-dehydrogenase activity
XOC_RS03185	COG2823	Periplasmic or secreted lipoprotein
XOC_RS03190	COG4251	negative regulation of phosphorylation
XOC_RS03195	COG0784	Response regulator, receiver
XOC_RS03200	COG4191	Histidine kinase
XOC_RS03205	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XOC_RS03220	COG2801	Transposase and inactivated derivatives
XOC_RS03235	COG3250	beta-galactosidase activity
XOC_RS03250	COG2188	Transcriptional regulator
XOC_RS03260	COG1609	Transcriptional regulator
XOC_RS03265	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XOC_RS03270	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XOC_RS03280	COG1215	transferase activity, transferring glycosyl groups
XOC_RS03285	COG1649	PFAM Uncharacterised BCR, COG1649
XOC_RS03285	COG0726	polysaccharide deacetylase
XOC_RS03295	COG2826	transposase and inactivated derivatives, IS30 family
XOC_RS03310	COG1012	belongs to the aldehyde dehydrogenase family
XOC_RS03340	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XOC_RS03365	COG2205	protein histidine kinase activity
XOC_RS03380	COG3039	Transposase
XOC_RS03390	COG2205	protein histidine kinase activity
XOC_RS03415	COG3791	Glutathione-dependent formaldehyde-activating
XOC_RS03440	COG0488	(ABC) transporter
XOC_RS03460	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XOC_RS03470	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XOC_RS03480	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XOC_RS03480	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XOC_RS03485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XOC_RS03485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XOC_RS03505	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XOC_RS03510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XOC_RS03515	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XOC_RS03540	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XOC_RS03545	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XOC_RS03555	COG2205	protein histidine kinase activity
XOC_RS03560	COG0745	RESPONSE REGULATOR receiver
XOC_RS03565	COG0277	FAD linked oxidase domain protein
XOC_RS03570	COG1988	membrane-bound metal-dependent
XOC_RS03575	COG0792	nuclease activity
XOC_RS03610	COG0275	rRNA processing
XOC_RS03615	COG3116	cell division
XOC_RS03630	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XOC_RS03635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XOC_RS03650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XOC_RS03655	COG1181	Belongs to the D-alanine--D-alanine ligase family
XOC_RS03660	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XOC_RS03675	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XOC_RS03685	COG1388	LysM domain
XOC_RS03685	COG4942	peptidase
XOC_RS03700	COG0494	nUDIX hydrolase
XOC_RS03710	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XOC_RS03720	COG1028	Short-chain dehydrogenase reductase Sdr
XOC_RS03720	COG3321	synthase
XOC_RS03720	COG0604	alcohol dehydrogenase
XOC_RS03765	COG2226	methyltransferase
XOC_RS03770	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XOC_RS03810	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XOC_RS03825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XOC_RS03840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XOC_RS03845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XOC_RS03860	COG0667	Aldo Keto reductase
XOC_RS03895	COG2175	clavaminate synthase activity
XOC_RS03905	COG4181	ATPase activity
XOC_RS03920	COG0642	Histidine kinase
XOC_RS03930	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XOC_RS03950	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XOC_RS03970	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XOC_RS03975	COG2967	ApaG domain
XOC_RS03980	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XOC_RS03985	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XOC_RS04000	COG0123	including yeast histone deacetylase and acetoin utilization protein
XOC_RS04005	COG2096	Adenosyltransferase
XOC_RS04015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XOC_RS04020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XOC_RS04050	COG3384	dioxygenase
XOC_RS04055	COG0583	DNA-binding transcription factor activity
XOC_RS04060	COG0318	PFAM AMP-dependent synthetase and ligase
XOC_RS04070	COG1024	Enoyl-CoA hydratase
XOC_RS04090	COG3386	PFAM SMP-30 Gluconolaconase
XOC_RS04115	COG0697	spore germination
XOC_RS04145	COG2197	response regulator
XOC_RS04155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XOC_RS04160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XOC_RS04170	COG0583	DNA-binding transcription factor activity
XOC_RS04175	COG3634	alkyl hydroperoxide reductase activity
XOC_RS04185	COG2890	protein-(glutamine-N5) methyltransferase activity
XOC_RS04230	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XOC_RS04270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XOC_RS04275	COG1404	Belongs to the peptidase S8 family
XOC_RS04280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XOC_RS04310	COG1295	ribonuclease BN
XOC_RS04315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XOC_RS04335	COG0521	Mo-molybdopterin cofactor biosynthetic process
XOC_RS04345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XOC_RS04350	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XOC_RS04360	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XOC_RS04375	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XOC_RS04385	COG0193	aminoacyl-tRNA hydrolase activity
XOC_RS04390	COG0012	GTP binding
XOC_RS04420	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XOC_RS04425	COG0250	Participates in transcription elongation, termination and antitermination
XOC_RS04430	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XOC_RS04435	COG0081	regulation of translation
XOC_RS04440	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XOC_RS04450	COG0085	RNA polymerase activity
XOC_RS04455	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XOC_RS04460	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XOC_RS04465	COG0049	tRNA binding
XOC_RS04485	COG0051	transcription antitermination factor activity, RNA binding
XOC_RS04495	COG0088	Forms part of the polypeptide exit tunnel
XOC_RS04500	COG0089	rRNA binding
XOC_RS04505	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XOC_RS04525	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XOC_RS04530	COG0255	Belongs to the universal ribosomal protein uL29 family
XOC_RS04535	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XOC_RS04540	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XOC_RS04545	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XOC_RS04550	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XOC_RS04580	COG1841	ribosomal large subunit assembly
XOC_RS04585	COG0200	Binds to the 23S rRNA
XOC_RS04590	COG0201	protein transport
XOC_RS04600	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XOC_RS04605	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XOC_RS04615	COG0203	ribosomal protein L17
XOC_RS04620	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XOC_RS04635	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XOC_RS04655	COG1217	gtp-binding protein TYPA
XOC_RS04660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XOC_RS04685	COG3039	Transposase
XOC_RS04695	COG0584	glycerophosphoryl diester phosphodiesterase
XOC_RS04715	COG1902	pentaerythritol trinitrate reductase activity
XOC_RS04715	COG0446	pyridine nucleotide-disulphide oxidoreductase
XOC_RS04720	COG0604	alcohol dehydrogenase
XOC_RS04745	COG0156	8-amino-7-oxononanoate synthase activity
XOC_RS04750	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XOC_RS04755	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XOC_RS04760	COG4208	sulfate ABC transporter
XOC_RS04765	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XOC_RS04800	COG0406	alpha-ribazole phosphatase activity
XOC_RS04805	COG0285	dihydrofolate synthase activity
XOC_RS04825	COG2833	Protein of unknown function (DUF455)
XOC_RS04830	COG3291	Pkd domain containing protein
XOC_RS04840	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XOC_RS04845	COG0671	phosphoesterase, PA-phosphatase related
XOC_RS04850	COG0438	transferase activity, transferring glycosyl groups
XOC_RS04860	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XOC_RS04875	COG4783	chaperone-mediated protein folding
XOC_RS04890	COG0473	3-isopropylmalate dehydrogenase activity
XOC_RS04920	COG2801	Transposase and inactivated derivatives
XOC_RS04925	COG2963	transposase activity
XOC_RS04940	COG0544	peptidyl-prolyl cis-trans isomerase activity
XOC_RS04980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XOC_RS05005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XOC_RS05010	COG0631	protein serine/threonine phosphatase activity
XOC_RS05025	COG0859	PFAM glycosyl transferase family 9
XOC_RS05030	COG3642	lipopolysaccharide core region biosynthetic process
XOC_RS05035	COG1234	tRNA 3'-trailer cleavage
XOC_RS05040	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XOC_RS05050	COG0315	cyclic pyranopterin monophosphate synthase activity
XOC_RS05055	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XOC_RS05060	COG0314	molybdopterin synthase activity
XOC_RS05075	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XOC_RS05085	COG0537	adenosine 5'-monophosphoramidase activity
XOC_RS05105	COG0714	Associated with various cellular activities
XOC_RS05125	COG1399	metal-binding, possibly nucleic acid-binding protein
XOC_RS05150	COG1028	Short-chain dehydrogenase reductase Sdr
XOC_RS05155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XOC_RS05165	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XOC_RS05170	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XOC_RS05200	COG3829	transcription factor binding
XOC_RS05215	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
XOC_RS05260	COG0678	peroxiredoxin activity
XOC_RS05280	COG0330	HflC and HflK could
XOC_RS05285	COG0330	HflC and HflK could
XOC_RS05300	COG0308	aminopeptidase N
XOC_RS05310	COG1028	Short-chain dehydrogenase reductase Sdr
XOC_RS05315	COG1309	transcriptional regulator
XOC_RS05355	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
XOC_RS05465	COG0587	DNA-directed DNA polymerase activity
XOC_RS05480	COG1297	OPT oligopeptide transporter protein
XOC_RS05495	COG0823	Involved in the tonB-independent uptake of proteins
XOC_RS05495	COG1506	peptidase
XOC_RS05505	COG2207	Transcriptional regulator
XOC_RS05505	COG1917	Cupin 2, conserved barrel domain protein
XOC_RS05525	COG0753	catalase activity
XOC_RS05540	COG3039	Transposase
XOC_RS05565	COG3551	Protein conserved in bacteria
XOC_RS05600	COG2194	sulfuric ester hydrolase activity
XOC_RS05610	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
XOC_RS05615	COG0745	RESPONSE REGULATOR receiver
XOC_RS05620	COG0642	Histidine kinase
XOC_RS05630	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XOC_RS05635	COG2894	cell division
XOC_RS05650	COG4585	Histidine kinase
XOC_RS05655	COG2197	response regulator
XOC_RS05670	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XOC_RS05700	COG2963	transposase activity
XOC_RS05850	COG3039	Transposase
XOC_RS05855	COG3179	chitinase
XOC_RS05895	COG2801	Transposase and inactivated derivatives
XOC_RS05900	COG2963	transposase activity
XOC_RS06115	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XOC_RS06130	COG1842	Phage shock protein A
XOC_RS06155	COG0754	glutathionylspermidine amidase activity
XOC_RS06240	COG0531	amino acid
XOC_RS06245	COG2197	response regulator
XOC_RS06255	COG1113	amino acid transport
XOC_RS06260	COG1271	oxidase subunit
XOC_RS06265	COG1294	oxidase, subunit
XOC_RS06275	COG2239	Acts as a magnesium transporter
XOC_RS06280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XOC_RS06285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XOC_RS06295	COG1660	Displays ATPase and GTPase activities
XOC_RS06305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XOC_RS06320	COG1137	ATPase activity
XOC_RS06325	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XOC_RS06335	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XOC_RS06345	COG0271	Belongs to the BolA IbaG family
XOC_RS06350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XOC_RS06370	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XOC_RS06385	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XOC_RS06395	COG0628	permease
XOC_RS06405	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XOC_RS06410	COG3178	'Phosphotransferase
XOC_RS06435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XOC_RS06440	COG1555	photosystem II stabilization
XOC_RS06455	COG3039	Transposase
XOC_RS06460	COG2146	nitrite reductase [NAD(P)H] activity
XOC_RS06470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XOC_RS06475	COG0719	Fe-S assembly protein
XOC_RS06480	COG0396	ATPase activity
XOC_RS06485	COG0719	Fe-S assembly protein
XOC_RS06490	COG1959	2 iron, 2 sulfur cluster binding
XOC_RS06540	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XOC_RS06565	COG0519	Catalyzes the synthesis of GMP from XMP
XOC_RS06580	COG1678	Uncharacterized ACR, COG1678
XOC_RS06585	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XOC_RS06595	COG1764	response to oxidative stress
XOC_RS06605	COG0384	phenazine biosynthesis protein PhzF
XOC_RS06615	COG0527	aspartate kinase activity
XOC_RS06650	COG0142	geranyltranstransferase activity
XOC_RS06655	COG0629	single-stranded DNA binding
XOC_RS06660	COG2203	Gaf domain
XOC_RS06660	COG3706	GGDEF domain
XOC_RS06660	COG4251	negative regulation of phosphorylation
XOC_RS06660	COG5001	Diguanylate cyclase
XOC_RS06665	COG3321	synthase
XOC_RS06665	COG0604	alcohol dehydrogenase
XOC_RS06665	COG1028	Short-chain dehydrogenase reductase Sdr
XOC_RS06675	COG2080	2 iron, 2 sulfur cluster binding
XOC_RS06680	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XOC_RS06685	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XOC_RS06690	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XOC_RS06715	COG2879	small protein
XOC_RS06720	COG1966	Carbon starvation protein
XOC_RS06725	COG1741	Belongs to the pirin family
XOC_RS06795	COG1741	Belongs to the pirin family
XOC_RS06805	COG1515	deoxyribonuclease V activity
XOC_RS06815	COG2801	Transposase and inactivated derivatives
XOC_RS06820	COG2963	transposase activity
XOC_RS06910	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XOC_RS06915	COG2199	diguanylate cyclase activity
XOC_RS06915	COG2202	Pas domain
XOC_RS06915	COG2200	EAL domain
XOC_RS06920	COG0835	chemotaxis
XOC_RS06925	COG0840	transmembrane signaling receptor activity
XOC_RS06930	COG0643	Histidine kinase
XOC_RS06930	COG2198	Histidine kinase
XOC_RS06940	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XOC_RS06950	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XOC_RS06955	COG2205	protein histidine kinase activity
XOC_RS06985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XOC_RS06990	COG0735	belongs to the Fur family
XOC_RS07105	COG5001	Diguanylate cyclase
XOC_RS07105	COG5002	protein histidine kinase activity
XOC_RS07110	COG1187	pseudouridine synthase activity
XOC_RS07125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XOC_RS07135	COG0475	glutathione-regulated potassium exporter activity
XOC_RS07140	COG5000	phosphorelay sensor kinase activity
XOC_RS07140	COG5002	protein histidine kinase activity
XOC_RS07145	COG0745	RESPONSE REGULATOR receiver
XOC_RS07150	COG1538	Outer membrane efflux protein
XOC_RS07175	COG1132	(ABC) transporter
XOC_RS07195	COG2826	transposase and inactivated derivatives, IS30 family
XOC_RS07235	COG3118	belongs to the thioredoxin family
XOC_RS07260	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XOC_RS07280	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XOC_RS07295	COG2968	Membrane
XOC_RS07310	COG3164	Protein of unknown function
XOC_RS07320	COG0312	modulator of DNA gyrase
XOC_RS07325	COG3028	Belongs to the UPF0307 family
XOC_RS07330	COG0312	modulator of DNA gyrase
XOC_RS07350	COG4104	PAAR repeat-containing protein
XOC_RS07355	COG0142	geranyltranstransferase activity
XOC_RS07360	COG1722	exodeoxyribonuclease VII activity
XOC_RS07365	COG0037	tRNA processing
XOC_RS07370	COG1785	Belongs to the alkaline phosphatase family
XOC_RS07375	COG1301	dicarboxylic acid transport
XOC_RS07390	COG0791	NLP P60 protein
XOC_RS07395	COG0791	NLP P60 protein
XOC_RS07400	COG1047	Peptidyl-prolyl cis-trans
XOC_RS07405	COG2311	Membrane
XOC_RS07410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XOC_RS07430	COG2963	transposase activity
XOC_RS07435	COG2801	Transposase and inactivated derivatives
XOC_RS07445	COG2801	Transposase and inactivated derivatives
XOC_RS07465	COG2801	Transposase and inactivated derivatives
XOC_RS07500	COG3590	peptidase
XOC_RS07520	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XOC_RS07530	COG2914	Belongs to the UPF0125 (RnfH) family
XOC_RS07535	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XOC_RS07545	COG0497	DNA recombination
XOC_RS07555	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XOC_RS07560	COG0443	Heat shock 70 kDa protein
XOC_RS07565	COG0484	heat shock protein binding
XOC_RS07570	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XOC_RS07585	COG0583	DNA-binding transcription factor activity
XOC_RS07590	COG1132	(ABC) transporter
XOC_RS07625	COG2850	peptidyl-arginine hydroxylation
XOC_RS07685	COG1131	(ABC) transporter
XOC_RS07690	COG1725	Transcriptional regulator
XOC_RS07700	COG0386	Belongs to the glutathione peroxidase family
XOC_RS07715	COG2900	Belongs to the SlyX family
XOC_RS07730	COG1609	Transcriptional regulator
XOC_RS07740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XOC_RS07760	COG2226	methyltransferase
XOC_RS07765	COG1960	acyl-CoA dehydrogenase activity
XOC_RS07785	COG0557	exoribonuclease II activity
XOC_RS07795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XOC_RS07805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XOC_RS07815	COG0704	Plays a role in the regulation of phosphate uptake
XOC_RS07830	COG0573	inorganic phosphate transmembrane transporter activity
XOC_RS07835	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XOC_RS07860	COG0659	secondary active sulfate transmembrane transporter activity
XOC_RS07865	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XOC_RS07875	COG1024	Enoyl-CoA hydratase
XOC_RS07885	COG0494	nUDIX hydrolase
XOC_RS07930	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XOC_RS07930	COG0116	Belongs to the methyltransferase superfamily
XOC_RS07935	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XOC_RS07950	COG0667	Aldo Keto reductase
XOC_RS07960	COG2925	Exonuclease
XOC_RS07970	COG3844	kynureninase activity
XOC_RS07985	COG0288	reversible hydration of carbon dioxide
XOC_RS08015	COG0316	Belongs to the HesB IscA family
XOC_RS08020	COG0360	Binds together with S18 to 16S ribosomal RNA
XOC_RS08040	COG3115	cell septum assembly
XOC_RS08055	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XOC_RS08065	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XOC_RS08080	COG2801	Transposase and inactivated derivatives
XOC_RS08085	COG2963	transposase activity
XOC_RS08095	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XOC_RS08110	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XOC_RS08165	COG0438	transferase activity, transferring glycosyl groups
XOC_RS08170	COG0438	transferase activity, transferring glycosyl groups
XOC_RS08180	COG0438	transferase activity, transferring glycosyl groups
XOC_RS08210	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XOC_RS08220	COG1960	acyl-CoA dehydrogenase activity
XOC_RS08230	COG3040	lipid binding
XOC_RS08255	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XOC_RS08260	COG0784	Response regulator, receiver
XOC_RS08260	COG4191	Histidine kinase
XOC_RS08270	COG1194	a g-specific adenine glycosylase
XOC_RS08280	COG0552	protein localization to endoplasmic reticulum
XOC_RS08290	COG3938	Belongs to the proline racemase family
XOC_RS08295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XOC_RS08310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XOC_RS08320	COG0006	proline dipeptidase activity
XOC_RS08335	COG0531	amino acid
XOC_RS08385	COG4206	TonB-dependent receptor
XOC_RS08400	COG0823	Involved in the tonB-independent uptake of proteins
XOC_RS08400	COG1506	peptidase
XOC_RS08430	COG0326	Molecular chaperone. Has ATPase activity
XOC_RS08435	COG0742	ribosomal rna small subunit methyltransferase
XOC_RS08440	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XOC_RS08455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XOC_RS08510	COG0343	queuine tRNA-ribosyltransferase activity
XOC_RS08515	COG1862	Preprotein translocase
XOC_RS08520	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XOC_RS08525	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XOC_RS08540	COG2963	transposase activity
XOC_RS08545	COG2801	Transposase and inactivated derivatives
XOC_RS08570	COG3039	Transposase
XOC_RS08580	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XOC_RS08580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XOC_RS08585	COG1105	Belongs to the carbohydrate kinase PfkB family
XOC_RS08590	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XOC_RS08590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XOC_RS08595	COG1609	Transcriptional regulator
XOC_RS08605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XOC_RS08610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XOC_RS08620	COG2902	Dehydrogenase
XOC_RS08630	COG0477	Major facilitator Superfamily
XOC_RS08640	COG0784	Response regulator, receiver
XOC_RS08640	COG5002	protein histidine kinase activity
XOC_RS08640	COG2205	protein histidine kinase activity
XOC_RS08645	COG2733	membrane
XOC_RS08655	COG1121	(ABC) transporter
XOC_RS08660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XOC_RS08675	COG0243	molybdopterin cofactor binding
XOC_RS08680	COG0477	Major facilitator Superfamily
XOC_RS08690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XOC_RS08695	COG0174	glutamine synthetase
XOC_RS08700	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XOC_RS08750	COG2801	Transposase and inactivated derivatives
XOC_RS08755	COG2201	protein-glutamate methylesterase activity
XOC_RS08770	COG3501	Rhs element vgr protein
XOC_RS08770	COG3409	Peptidoglycan-binding domain 1 protein
XOC_RS08785	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XOC_RS08805	COG3842	ATPase activity
XOC_RS08810	COG1176	ABC-type spermidine putrescine transport system, permease component I
XOC_RS08815	COG1177	transmembrane transport
XOC_RS08820	COG1012	belongs to the aldehyde dehydrogenase family
XOC_RS08835	COG4535	Mg2 and Co2 transporter CorC
XOC_RS08855	COG1702	phosphate starvation-inducible protein PhoH
XOC_RS08875	COG0741	lytic transglycosylase activity
XOC_RS08880	COG0723	plastoquinol--plastocyanin reductase activity
XOC_RS08885	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XOC_RS08890	COG2857	Cytochrome c1
XOC_RS08895	COG0625	glutathione transferase activity
XOC_RS08900	COG2969	positive regulation of protein catabolic process
XOC_RS08925	COG0840	transmembrane signaling receptor activity
XOC_RS08930	COG0835	chemotaxis
XOC_RS09040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XOC_RS09095	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XOC_RS09110	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XOC_RS09115	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XOC_RS09115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XOC_RS09120	COG0802	atpase or kinase
XOC_RS09125	COG0860	N-Acetylmuramoyl-L-alanine amidase
XOC_RS09130	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XOC_RS09150	COG1028	Short-chain dehydrogenase reductase Sdr
XOC_RS09170	COG2081	HI0933 family
XOC_RS09175	COG4681	YaeQ
XOC_RS09180	COG1671	Belongs to the UPF0178 family
XOC_RS09185	COG1278	Cold shock
XOC_RS09190	COG0625	glutathione transferase activity
XOC_RS09200	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XOC_RS09210	COG0513	Belongs to the DEAD box helicase family
XOC_RS09215	COG0488	(ABC) transporter
XOC_RS09235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XOC_RS09240	COG0483	inositol monophosphate 1-phosphatase activity
XOC_RS09255	COG3300	MHYT domain
XOC_RS09255	COG5001	Diguanylate cyclase
XOC_RS09260	COG1509	lysine 2,3-aminomutase activity
XOC_RS09275	COG0402	S-adenosylhomocysteine deaminase activity
XOC_RS09280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XOC_RS09320	COG1741	Belongs to the pirin family
XOC_RS09325	COG0583	DNA-binding transcription factor activity
XOC_RS09350	COG0352	thiamine-phosphate diphosphorylase activity
XOC_RS09350	COG0351	phosphomethylpyrimidine kinase
XOC_RS09360	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XOC_RS09365	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XOC_RS09380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XOC_RS09390	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XOC_RS09395	COG3734	2-keto-3-deoxy-galactonokinase
XOC_RS09405	COG4948	Mandelate Racemase Muconate Lactonizing
XOC_RS09410	COG0800	Aldolase
XOC_RS09435	COG1070	Carbohydrate kinase
XOC_RS09445	COG0477	Major facilitator Superfamily
XOC_RS09450	COG0860	N-Acetylmuramoyl-L-alanine amidase
XOC_RS09455	COG1469	GTP cyclohydrolase I activity
XOC_RS09465	COG0617	tRNA 3'-terminal CCA addition
XOC_RS09485	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XOC_RS09510	COG1472	Belongs to the glycosyl hydrolase 3 family
XOC_RS09520	COG5001	Diguanylate cyclase
XOC_RS09520	COG3706	GGDEF domain
XOC_RS09520	COG4251	negative regulation of phosphorylation
XOC_RS09520	COG2203	Gaf domain
XOC_RS09525	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XOC_RS09530	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XOC_RS09545	COG0671	phosphoesterase, PA-phosphatase related
XOC_RS09555	COG1794	racemase activity, acting on amino acids and derivatives
XOC_RS09560	COG0697	spore germination
XOC_RS09565	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XOC_RS09585	COG1012	belongs to the aldehyde dehydrogenase family
XOC_RS09610	COG2963	transposase activity
XOC_RS09615	COG2801	Transposase and inactivated derivatives
XOC_RS09630	COG2801	Transposase and inactivated derivatives
XOC_RS09635	COG2963	transposase activity
XOC_RS09650	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XOC_RS09665	COG0124	histidyl-tRNA synthetase
XOC_RS09675	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XOC_RS09690	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XOC_RS09690	COG0131	Imidazoleglycerol-phosphate dehydratase
XOC_RS09700	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XOC_RS09710	COG0140	phosphoribosyl-ATP diphosphatase activity
XOC_RS09710	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XOC_RS09735	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XOC_RS09740	COG0235	Class ii aldolase
XOC_RS09745	COG0531	amino acid
XOC_RS09750	COG0531	amino acid
XOC_RS09760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XOC_RS09765	COG0277	FAD linked oxidase domain protein
XOC_RS09785	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XOC_RS09835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XOC_RS09840	COG2258	MOSC domain
XOC_RS09845	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XOC_RS09850	COG0505	Belongs to the CarA family
XOC_RS09860	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XOC_RS09865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XOC_RS09875	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XOC_RS09890	COG3279	Response regulator of the LytR AlgR family
XOC_RS09895	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XOC_RS09910	COG2205	protein histidine kinase activity
XOC_RS09910	COG2198	Histidine kinase
XOC_RS09910	COG0784	Response regulator, receiver
XOC_RS09915	COG1024	Enoyl-CoA hydratase
XOC_RS09920	COG0318	PFAM AMP-dependent synthetase and ligase
XOC_RS09950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XOC_RS09975	COG0840	transmembrane signaling receptor activity
XOC_RS09985	COG0835	chemotaxis
XOC_RS09995	COG0840	transmembrane signaling receptor activity
XOC_RS10000	COG0840	transmembrane signaling receptor activity
XOC_RS10005	COG0840	transmembrane signaling receptor activity
XOC_RS10010	COG0840	transmembrane signaling receptor activity
XOC_RS10015	COG0840	transmembrane signaling receptor activity
XOC_RS10020	COG0840	transmembrane signaling receptor activity
XOC_RS10025	COG0840	transmembrane signaling receptor activity
XOC_RS10030	COG0840	transmembrane signaling receptor activity
XOC_RS10040	COG0840	transmembrane signaling receptor activity
XOC_RS10045	COG0840	transmembrane signaling receptor activity
XOC_RS10055	COG0840	transmembrane signaling receptor activity
XOC_RS10065	COG0745	RESPONSE REGULATOR receiver
XOC_RS10075	COG0835	chemotaxis
XOC_RS10080	COG1192	Involved in chromosome partitioning
XOC_RS10085	COG1360	Flagellar Motor Protein
XOC_RS10090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XOC_RS10105	COG4774	siderophore transport
XOC_RS10110	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XOC_RS10190	COG2198	Histidine kinase
XOC_RS10190	COG0784	Response regulator, receiver
XOC_RS10190	COG0643	Histidine kinase
XOC_RS10245	COG1684	flagellar biosynthetic protein fliR
XOC_RS10260	COG3190	flagellar
XOC_RS10310	COG1677	Flagellar hook-basal body complex protein FliE
XOC_RS10340	COG1028	Short-chain dehydrogenase reductase Sdr
XOC_RS10345	COG4221	oxidoreductase activity
XOC_RS10350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XOC_RS10370	COG2201	protein-glutamate methylesterase activity
XOC_RS10400	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XOC_RS10405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XOC_RS10440	COG4787	bacterial-type flagellum-dependent cell motility
XOC_RS10450	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XOC_RS10455	COG1558	bacterial-type flagellum-dependent cell motility
XOC_RS10465	COG0784	Response regulator, receiver
XOC_RS10465	COG0835	chemotaxis
XOC_RS10485	COG4191	Histidine kinase
XOC_RS10495	COG4585	Histidine kinase
XOC_RS10535	COG0482	sulfurtransferase activity
XOC_RS10550	COG0542	response to heat
XOC_RS10580	COG0492	ferredoxin-NADP+ reductase activity
XOC_RS10585	COG1674	ftsk spoiiie
XOC_RS10605	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XOC_RS10625	COG0038	chloride channel
XOC_RS10630	COG0183	Belongs to the thiolase family
XOC_RS10635	COG1024	Enoyl-CoA hydratase
XOC_RS10635	COG1250	3-hydroxyacyl-CoA dehydrogenase
XOC_RS10650	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XOC_RS10670	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XOC_RS10675	COG1160	GTP binding
XOC_RS10680	COG0303	'Molybdopterin
XOC_RS10690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XOC_RS10715	COG3039	Transposase
XOC_RS10725	COG3039	Transposase
XOC_RS10735	COG3039	Transposase
XOC_RS10755	COG0746	molybdenum cofactor guanylyltransferase activity
XOC_RS10780	COG1648	precorrin-2 dehydrogenase activity
XOC_RS10780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XOC_RS10815	COG3039	Transposase
XOC_RS10825	COG5001	Diguanylate cyclase
XOC_RS10840	COG4566	intracellular signal transduction
XOC_RS10880	COG2201	protein-glutamate methylesterase activity
XOC_RS10885	COG2963	transposase activity
XOC_RS10910	COG2801	Transposase and inactivated derivatives
XOC_RS10945	COG3039	Transposase
XOC_RS10950	COG3039	Transposase
XOC_RS10955	COG3039	Transposase
XOC_RS10975	COG3039	Transposase
XOC_RS11000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XOC_RS11005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XOC_RS11050	COG3328	transposase activity
XOC_RS11065	COG1858	cytochrome C peroxidase
XOC_RS11090	COG0515	serine threonine protein kinase
XOC_RS11095	COG0631	protein serine/threonine phosphatase activity
XOC_RS11140	COG3039	Transposase
XOC_RS11145	COG2826	transposase and inactivated derivatives, IS30 family
XOC_RS11255	COG2963	transposase activity
XOC_RS11270	COG2154	pterin-4-alpha-carbinolamine dehydratase
XOC_RS11285	COG3064	Membrane
XOC_RS11295	COG1530	ribonuclease E activity
XOC_RS11305	COG1054	Belongs to the UPF0176 family
XOC_RS11325	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XOC_RS11340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XOC_RS11365	COG0582	viral genome integration into host DNA
XOC_RS11390	COG0322	excinuclease ABC activity
XOC_RS11400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XOC_RS11410	COG1663	tetraacyldisaccharide 4'-kinase activity
XOC_RS11425	COG0811	peptide transport
XOC_RS11450	COG4591	ABC-type transport system involved in lipoprotein release permease component
XOC_RS11465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XOC_RS11480	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XOC_RS11490	COG0354	folic acid binding
XOC_RS11500	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XOC_RS11510	COG0363	glucosamine-6-phosphate deaminase activity
XOC_RS11515	COG0129	dihydroxy-acid dehydratase activity
XOC_RS11520	COG0800	Aldolase
XOC_RS11530	COG2826	transposase and inactivated derivatives, IS30 family
XOC_RS11610	COG3039	Transposase
XOC_RS11700	COG2205	protein histidine kinase activity
XOC_RS11700	COG0784	Response regulator, receiver
XOC_RS11705	COG2183	response to ionizing radiation
XOC_RS11715	COG0723	plastoquinol--plastocyanin reductase activity
XOC_RS11715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XOC_RS11730	COG3243	poly(R)-hydroxyalkanoic acid synthase
XOC_RS11740	COG1183	phosphatidylcholine synthase activity
XOC_RS11745	COG1028	Short-chain dehydrogenase reductase Sdr
XOC_RS11770	COG0668	transmembrane transport
XOC_RS11790	COG1914	H( )-stimulated, divalent metal cation uptake system
XOC_RS11810	COG0583	DNA-binding transcription factor activity
XOC_RS11815	COG0583	DNA-binding transcription factor activity
XOC_RS11835	COG0583	DNA-binding transcription factor activity
XOC_RS11840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XOC_RS11845	COG3002	Belongs to the UPF0753 family
XOC_RS11850	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XOC_RS11850	COG0519	Catalyzes the synthesis of GMP from XMP
XOC_RS11860	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XOC_RS11875	COG0475	glutathione-regulated potassium exporter activity
XOC_RS11875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XOC_RS11880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XOC_RS11890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XOC_RS11895	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XOC_RS11905	COG0776	regulation of translation
XOC_RS11910	COG0539	negative regulation of cytoplasmic translation
XOC_RS11915	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XOC_RS11930	COG2957	Belongs to the agmatine deiminase family
XOC_RS11935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XOC_RS11960	COG0395	ABC-type sugar transport system, permease component
XOC_RS11965	COG1175	transmembrane transport
XOC_RS11995	COG2350	Protein conserved in bacteria
XOC_RS12000	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XOC_RS12005	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XOC_RS12010	COG1187	pseudouridine synthase activity
XOC_RS12030	COG0436	Aminotransferase
XOC_RS12035	COG4133	protoheme IX ABC transporter activity
XOC_RS12095	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XOC_RS12100	COG4988	ABC transporter
XOC_RS12110	COG1271	oxidase subunit
XOC_RS12115	COG1294	oxidase, subunit
XOC_RS12160	COG0165	Argininosuccinate lyase
XOC_RS12175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XOC_RS12180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XOC_RS12190	COG0137	argininosuccinate synthase activity
XOC_RS12195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XOC_RS12210	COG2166	iron-sulfur cluster assembly
XOC_RS12240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XOC_RS12260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XOC_RS12270	COG0305	Participates in initiation and elongation during chromosome replication
XOC_RS12280	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XOC_RS12285	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XOC_RS12290	COG2137	regulation of response to DNA damage stimulus
XOC_RS12295	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XOC_RS12310	COG1546	Belongs to the CinA family
XOC_RS12315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XOC_RS12330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XOC_RS12340	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XOC_RS12345	COG1534	Rna-binding protein
XOC_RS12350	COG3737	Protein of unknown function (DUF498/DUF598)
XOC_RS12360	COG1238	metal cluster binding
XOC_RS12365	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XOC_RS12370	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XOC_RS12375	COG2840	Smr protein MutS2
XOC_RS12385	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XOC_RS12395	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XOC_RS12400	COG0148	phosphopyruvate hydratase activity
XOC_RS12410	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XOC_RS12415	COG0504	CTP synthase activity
XOC_RS12450	COG1253	flavin adenine dinucleotide binding
XOC_RS12465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XOC_RS12470	COG2271	Major facilitator Superfamily
XOC_RS12475	COG1132	(ABC) transporter
XOC_RS12480	COG1136	(ABC) transporter
XOC_RS12495	COG0438	transferase activity, transferring glycosyl groups
XOC_RS12505	COG2264	protein methyltransferase activity
XOC_RS12535	COG2244	polysaccharide biosynthetic process
XOC_RS12585	COG1595	DNA-templated transcription, initiation
XOC_RS12600	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XOC_RS12620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XOC_RS12645	COG3039	Transposase
XOC_RS12660	COG0840	transmembrane signaling receptor activity
XOC_RS12670	COG2801	Transposase and inactivated derivatives
XOC_RS12690	COG2826	transposase and inactivated derivatives, IS30 family
XOC_RS12705	COG3039	Transposase
XOC_RS12735	COG0583	DNA-binding transcription factor activity
XOC_RS12745	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XOC_RS12760	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XOC_RS12765	COG1605	Chorismate mutase
XOC_RS12765	COG0077	Prephenate dehydratase
XOC_RS12770	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XOC_RS12775	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XOC_RS12815	COG1228	amidohydrolase
XOC_RS12820	COG2986	histidine ammonia-lyase
XOC_RS12830	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XOC_RS12850	COG2963	transposase activity
XOC_RS12865	COG0556	nucleotide-excision repair
XOC_RS12870	COG4969	Belongs to the N-Me-Phe pilin family
XOC_RS12910	COG1611	Belongs to the LOG family
XOC_RS12920	COG2095	MarC family integral membrane protein
XOC_RS12930	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XOC_RS12965	COG1185	polyribonucleotide nucleotidyltransferase activity
XOC_RS12970	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XOC_RS12985	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XOC_RS12990	COG0195	Participates in both transcription termination and antitermination
XOC_RS12995	COG0779	Required for maturation of 30S ribosomal subunits
XOC_RS13005	COG1007	ATP synthesis coupled electron transport
XOC_RS13035	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XOC_RS13040	COG1034	ATP synthesis coupled electron transport
XOC_RS13045	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XOC_RS13050	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XOC_RS13055	COG0649	NAD binding
XOC_RS13060	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XOC_RS13070	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XOC_RS13085	COG0149	triose-phosphate isomerase activity
XOC_RS13120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XOC_RS13125	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XOC_RS13140	COG0133	tryptophan synthase activity
XOC_RS13150	COG0135	phosphoribosylanthranilate isomerase activity
XOC_RS13155	COG0101	tRNA pseudouridine synthase activity
XOC_RS13170	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XOC_RS13175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XOC_RS13180	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XOC_RS13185	COG2890	protein-(glutamine-N5) methyltransferase activity
XOC_RS13205	COG0433	COG0433 Predicted ATPase
XOC_RS13220	COG2801	Transposase and inactivated derivatives
XOC_RS13235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XOC_RS13245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XOC_RS13270	COG0717	Belongs to the dCTP deaminase family
XOC_RS13275	COG0489	protein tyrosine kinase activity
XOC_RS13280	COG3293	Transposase
XOC_RS13290	COG3706	GGDEF domain
XOC_RS13310	COG1028	Short-chain dehydrogenase reductase Sdr
XOC_RS13315	COG3039	Transposase
XOC_RS13325	COG0415	Belongs to the DNA photolyase family
XOC_RS13330	COG0305	Participates in initiation and elongation during chromosome replication
XOC_RS13340	COG0367	asparagine synthase
XOC_RS13355	COG1960	acyl-CoA dehydrogenase activity
XOC_RS13370	COG0084	hydrolase, TatD family'
XOC_RS13375	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XOC_RS13430	COG0386	Belongs to the glutathione peroxidase family
XOC_RS13525	COG2814	Major facilitator Superfamily
XOC_RS13530	COG1566	PFAM secretion protein HlyD family protein
XOC_RS13565	COG4774	siderophore transport
XOC_RS13580	COG0367	asparagine synthase
XOC_RS13585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XOC_RS13595	COG1393	Belongs to the ArsC family
XOC_RS13655	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XOC_RS13670	COG0233	cytoplasmic translational termination
XOC_RS13680	COG0575	Belongs to the CDS family
XOC_RS13685	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XOC_RS13690	COG0750	zinc metalloprotease
XOC_RS13700	COG3039	Transposase
XOC_RS13705	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XOC_RS13710	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XOC_RS13715	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XOC_RS13735	COG0825	malonyl-CoA metabolic process
XOC_RS13755	COG1981	membrane
XOC_RS13775	COG1695	Transcriptional regulator
XOC_RS13805	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XOC_RS13815	COG2040	homocysteine
XOC_RS13820	COG0833	amino acid
XOC_RS13825	COG0346	lactoylglutathione lyase activity
XOC_RS13835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XOC_RS13835	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XOC_RS13845	COG2878	Part of a membrane complex involved in electron transport
XOC_RS13865	COG1595	DNA-templated transcription, initiation
XOC_RS13890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XOC_RS13905	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XOC_RS13910	COG0251	oxidation-reduction process
XOC_RS13920	COG0392	lysyltransferase activity
XOC_RS13920	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XOC_RS13950	COG2814	Major facilitator Superfamily
XOC_RS13955	COG1902	pentaerythritol trinitrate reductase activity
XOC_RS13965	COG2824	Alkylphosphonate utilization operon protein PhnA
XOC_RS13975	COG1047	Peptidyl-prolyl cis-trans
XOC_RS14010	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XOC_RS14025	COG1451	nucleotide metabolic process
XOC_RS14040	COG0183	Belongs to the thiolase family
XOC_RS14070	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XOC_RS14070	COG1793	dna ligase
XOC_RS14080	COG1793	dna ligase
XOC_RS14085	COG1201	RNA secondary structure unwinding
XOC_RS14100	COG1278	Cold shock
XOC_RS14105	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XOC_RS14110	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XOC_RS14120	COG3046	protein related to deoxyribodipyrimidine photolyase
XOC_RS14125	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XOC_RS14130	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XOC_RS14135	COG2954	triphosphatase activity
XOC_RS14150	COG1381	Involved in DNA repair and RecF pathway recombination
XOC_RS14170	COG0681	Belongs to the peptidase S26 family
XOC_RS14175	COG0481	GTPase activity
XOC_RS14180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XOC_RS14220	COG1960	acyl-CoA dehydrogenase activity
XOC_RS14245	COG3250	beta-galactosidase activity
XOC_RS14280	COG5002	protein histidine kinase activity
XOC_RS14280	COG0784	Response regulator, receiver
XOC_RS14285	COG0784	Response regulator, receiver
XOC_RS14285	COG2198	Histidine kinase
XOC_RS14285	COG2205	protein histidine kinase activity
XOC_RS14290	COG2353	YceI-like domain
XOC_RS14320	COG1760	l-serine dehydratase
XOC_RS14330	COG0626	cystathionine gamma-synthase activity
XOC_RS14335	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XOC_RS14340	COG0739	heme binding
XOC_RS14350	COG1272	protein, Hemolysin III
XOC_RS14360	COG0517	IMP dehydrogenase activity
XOC_RS14360	COG0516	GMP reductase activity
XOC_RS14365	COG0463	Glycosyl transferase, family 2
XOC_RS14375	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XOC_RS14385	COG4771	TonB-dependent receptor
XOC_RS14390	COG1309	transcriptional regulator
XOC_RS14400	COG1960	acyl-CoA dehydrogenase activity
XOC_RS14425	COG0509	glycine decarboxylation via glycine cleavage system
XOC_RS14440	COG0330	HflC and HflK could
XOC_RS14445	COG1742	UPF0060 membrane protein
XOC_RS14450	COG3956	TIGRFAM MazG family protein
XOC_RS14460	COG0494	nUDIX hydrolase
XOC_RS14470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XOC_RS14475	COG0837	glucose binding
XOC_RS14490	COG1388	LysM domain
XOC_RS14490	COG3858	chitin binding
XOC_RS14495	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XOC_RS14505	COG1472	Belongs to the glycosyl hydrolase 3 family
XOC_RS14530	COG3537	Alpha-1,2-mannosidase
XOC_RS14570	COG3142	Participates in the control of copper homeostasis
XOC_RS14575	COG1446	asparaginase
XOC_RS14665	COG2198	Histidine kinase
XOC_RS14665	COG0784	Response regulator, receiver
XOC_RS14665	COG0643	Histidine kinase
XOC_RS14670	COG0840	transmembrane signaling receptor activity
XOC_RS14675	COG0835	chemotaxis
XOC_RS14690	COG0189	ligase activity
XOC_RS14700	COG1397	ADP-ribosylglycohydrolase
XOC_RS14710	COG1199	ATP-dependent helicase activity
XOC_RS14720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XOC_RS14725	COG1215	transferase activity, transferring glycosyl groups
XOC_RS14735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XOC_RS14790	COG1643	Atp-dependent helicase
XOC_RS14795	COG0783	Belongs to the Dps family
XOC_RS14800	COG0514	ATP-dependent DNA helicase (RecQ)
XOC_RS14815	COG1187	pseudouridine synthase activity
XOC_RS14825	COG0840	transmembrane signaling receptor activity
XOC_RS14850	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XOC_RS14860	COG0602	queuosine metabolic process
XOC_RS14870	COG2885	chlorophyll binding
XOC_RS14875	COG0823	Involved in the tonB-independent uptake of proteins
XOC_RS14895	COG0824	Thioesterase
XOC_RS14900	COG2255	four-way junction helicase activity
XOC_RS14935	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XOC_RS14950	COG0477	Major facilitator Superfamily
XOC_RS14965	COG0657	acetylesterase activity
XOC_RS14965	COG2755	lipolytic protein G-D-S-L family
XOC_RS14985	COG0488	(ABC) transporter
XOC_RS15015	COG4651	solute:proton antiporter activity
XOC_RS15015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XOC_RS15020	COG2801	Transposase and inactivated derivatives
XOC_RS15030	COG4772	TonB-dependent receptor
XOC_RS15040	COG4264	IucA IucC family
XOC_RS15045	COG2814	Major facilitator Superfamily
XOC_RS15055	COG0019	diaminopimelate decarboxylase activity
XOC_RS15100	COG4206	TonB-dependent receptor
XOC_RS15110	COG2963	transposase activity
XOC_RS15115	COG0542	response to heat
XOC_RS15140	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XOC_RS15150	COG2826	transposase and inactivated derivatives, IS30 family
XOC_RS15155	COG0534	Mate efflux family protein
XOC_RS15165	COG0336	Belongs to the RNA methyltransferase TrmD family
XOC_RS15170	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XOC_RS15175	COG0228	four-way junction DNA binding
XOC_RS15200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XOC_RS15210	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XOC_RS15250	COG2172	sigma factor antagonist activity
XOC_RS15255	COG1366	Belongs to the anti-sigma-factor antagonist family
XOC_RS15260	COG1366	Belongs to the anti-sigma-factor antagonist family
XOC_RS15275	COG0326	Molecular chaperone. Has ATPase activity
XOC_RS15280	COG2207	Transcriptional regulator
XOC_RS15305	COG2963	transposase activity
XOC_RS15345	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XOC_RS15350	COG1845	cytochrome c oxidase, subunit III
XOC_RS15355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XOC_RS15370	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XOC_RS15375	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XOC_RS15385	COG0196	riboflavin kinase activity
XOC_RS15390	COG0728	peptidoglycan biosynthetic process
XOC_RS15395	COG0268	Binds directly to 16S ribosomal RNA
XOC_RS15400	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XOC_RS15405	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XOC_RS15415	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XOC_RS15420	COG0824	Thioesterase
XOC_RS15435	COG1946	Acyl-CoA thioesterase
XOC_RS15445	COG1595	DNA-templated transcription, initiation
XOC_RS15460	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XOC_RS15475	COG3293	Transposase
XOC_RS15505	COG1877	trehalose-phosphatase activity
XOC_RS15510	COG3387	PFAM Glycoside hydrolase 15-related
XOC_RS15525	COG0840	transmembrane signaling receptor activity
XOC_RS15530	COG3011	Protein conserved in bacteria
XOC_RS15545	COG0564	pseudouridine synthase activity
XOC_RS15550	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XOC_RS15555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XOC_RS15555	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XOC_RS15565	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XOC_RS15570	COG0045	succinate-CoA ligase (ADP-forming) activity
XOC_RS15585	COG2184	nucleotidyltransferase activity
XOC_RS15605	COG2194	sulfuric ester hydrolase activity
XOC_RS15610	COG4969	Belongs to the N-Me-Phe pilin family
XOC_RS15620	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XOC_RS15630	COG3039	Transposase
XOC_RS15635	COG3209	COG3209 Rhs family protein
XOC_RS15665	COG0745	RESPONSE REGULATOR receiver
XOC_RS15705	COG3039	Transposase
XOC_RS15765	COG2022	thiamine diphosphate biosynthetic process
XOC_RS15775	COG3273	potassium ion transport
XOC_RS15775	COG0471	metal ion transport
XOC_RS15795	COG1970	mechanosensitive ion channel activity
XOC_RS15800	COG3328	transposase activity
XOC_RS15805	COG2801	Transposase and inactivated derivatives
XOC_RS15810	COG2963	transposase activity
XOC_RS15820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XOC_RS15840	COG0308	aminopeptidase N
XOC_RS15845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XOC_RS15855	COG2895	sulfate adenylyltransferase (ATP) activity
XOC_RS15855	COG0529	Catalyzes the synthesis of activated sulfate
XOC_RS15860	COG0175	sulfate reduction
XOC_RS15865	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XOC_RS15870	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XOC_RS15875	COG0175	sulfate reduction
XOC_RS15895	COG2205	protein histidine kinase activity
XOC_RS15895	COG2198	Histidine kinase
XOC_RS15895	COG0784	Response regulator, receiver
XOC_RS15925	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XOC_RS15930	COG3588	fructose-bisphosphate aldolase
XOC_RS15935	COG0469	pyruvate kinase activity
XOC_RS15945	COG0126	phosphoglycerate kinase activity
XOC_RS15955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XOC_RS15970	COG3453	Protein conserved in bacteria
XOC_RS15970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XOC_RS15975	COG0725	ABC transporter, periplasmic molybdate-binding protein
XOC_RS15980	COG4149	molybdate abc transporter
XOC_RS15985	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XOC_RS16030	COG1022	Amp-dependent synthetase and ligase
XOC_RS16070	COG1376	ErfK ybiS ycfS ynhG family protein
XOC_RS16080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XOC_RS16085	COG1301	dicarboxylic acid transport
XOC_RS16090	COG2963	transposase activity
XOC_RS16115	COG2304	oxidoreductase activity
XOC_RS16135	COG0714	Associated with various cellular activities
XOC_RS16165	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XOC_RS16190	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XOC_RS16200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XOC_RS16215	COG1561	YicC-like family, N-terminal region
XOC_RS16220	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XOC_RS16225	COG0346	lactoylglutathione lyase activity
XOC_RS16235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XOC_RS16260	COG0006	proline dipeptidase activity
XOC_RS16280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XOC_RS16300	COG2912	Transglutaminase-like superfamily
XOC_RS16305	COG1773	rubredoxin
XOC_RS16310	COG0352	thiamine-phosphate diphosphorylase activity
XOC_RS16320	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XOC_RS16345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XOC_RS16380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XOC_RS16385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XOC_RS16405	COG1028	Short-chain dehydrogenase reductase Sdr
XOC_RS16425	COG3781	membrane
XOC_RS16435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XOC_RS16475	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XOC_RS16485	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XOC_RS16505	COG3710	Transcriptional regulator
XOC_RS16510	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XOC_RS16515	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XOC_RS16545	COG2226	methyltransferase
XOC_RS16550	COG0066	3-isopropylmalate dehydratase activity
XOC_RS16555	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XOC_RS16575	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XOC_RS16580	COG1538	Outer membrane efflux protein
XOC_RS16585	COG1519	Transferase
XOC_RS16590	COG1560	Kdo2-lipid A biosynthetic process
XOC_RS16620	COG0280	phosphate acetyltransferase
XOC_RS16620	COG0281	malic enzyme
XOC_RS16635	COG4191	Histidine kinase
XOC_RS16650	COG0583	DNA-binding transcription factor activity
XOC_RS16675	COG2197	response regulator
XOC_RS16685	COG0642	Histidine kinase
XOC_RS16700	COG2851	Citrate transporter
XOC_RS16705	COG1028	Short-chain dehydrogenase reductase Sdr
XOC_RS16710	COG1609	Transcriptional regulator
XOC_RS16720	COG2211	Major facilitator Superfamily
XOC_RS16750	COG0436	Aminotransferase
XOC_RS16765	COG0726	polysaccharide deacetylase
XOC_RS16770	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XOC_RS16790	COG3964	amidohydrolase
XOC_RS16795	COG0402	S-adenosylhomocysteine deaminase activity
XOC_RS16815	COG0242	peptide deformylase activity
XOC_RS16840	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XOC_RS16885	COG2188	Transcriptional regulator
XOC_RS16900	COG1450	Type ii and iii secretion system protein
XOC_RS16915	COG3166	PFAM Fimbrial assembly family protein
XOC_RS16920	COG3156	type II secretion system protein K
XOC_RS16925	COG4795	General secretion pathway protein
XOC_RS16930	COG2165	general secretion pathway protein
XOC_RS16935	COG4970	Tfp pilus assembly protein FimT
XOC_RS16940	COG2165	general secretion pathway protein
XOC_RS16945	COG1459	type II secretion system
XOC_RS16950	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XOC_RS16955	COG1404	Belongs to the peptidase S8 family
XOC_RS16960	COG5295	Hep Hag repeat protein
XOC_RS16965	COG0047	phosphoribosylformylglycinamidine synthase activity
XOC_RS16965	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XOC_RS16970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XOC_RS16975	COG4974	Belongs to the 'phage' integrase family
XOC_RS16990	COG0795	lipopolysaccharide-transporting ATPase activity
XOC_RS17000	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XOC_RS17015	COG0525	valine-tRNA ligase activity
XOC_RS17040	COG1183	phosphatidylcholine synthase activity
XOC_RS17050	COG0442	prolyl-tRNA aminoacylation
XOC_RS17065	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XOC_RS17070	COG1127	ABC transporter
XOC_RS17075	COG3218	ABC-type transport auxiliary lipoprotein component
XOC_RS17075	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XOC_RS17110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XOC_RS17115	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XOC_RS17115	COG0662	Cupin 2, conserved barrel domain protein
XOC_RS17140	COG2086	electron transfer activity
XOC_RS17155	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XOC_RS17155	COG0546	phosphoglycolate phosphatase activity
XOC_RS17160	COG0277	FAD linked oxidase domain protein
XOC_RS17175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XOC_RS17230	COG3754	Rhamnan synthesis protein F
XOC_RS17235	COG1216	Glycosyl transferase, family 2
XOC_RS17235	COG0438	transferase activity, transferring glycosyl groups
XOC_RS17240	COG0110	maltose O-acetyltransferase activity
XOC_RS17255	COG0626	cystathionine gamma-synthase activity
XOC_RS17290	COG0625	glutathione transferase activity
XOC_RS17300	COG0513	Belongs to the DEAD box helicase family
XOC_RS17305	COG0720	synthase
XOC_RS17315	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XOC_RS17320	COG1956	GAF domain-containing protein
XOC_RS17330	COG0546	phosphoglycolate phosphatase activity
XOC_RS17355	COG0339	signal peptide processing
XOC_RS17400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XOC_RS17405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XOC_RS17410	COG1136	(ABC) transporter
XOC_RS17420	COG1136	(ABC) transporter
XOC_RS17420	COG0577	efflux transmembrane transporter activity
XOC_RS17425	COG1136	(ABC) transporter
XOC_RS17425	COG0577	efflux transmembrane transporter activity
XOC_RS17430	COG0577	efflux transmembrane transporter activity
XOC_RS17430	COG1136	(ABC) transporter
XOC_RS17440	COG4191	Histidine kinase
XOC_RS17465	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XOC_RS17470	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XOC_RS17475	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XOC_RS17485	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XOC_RS17495	COG0356	it plays a direct role in the translocation of protons across the membrane
XOC_RS17515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XOC_RS17525	COG0508	dehydrogenase complex catalyzes the overall conversion of
XOC_RS17560	COG2011	ABC-type metal ion transport system permease component
XOC_RS17570	COG0697	spore germination
XOC_RS17605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XOC_RS17610	COG1187	pseudouridine synthase activity
XOC_RS17615	COG2813	Specifically methylates the guanine in position
XOC_RS17640	COG2205	protein histidine kinase activity
XOC_RS17640	COG2202	Pas domain
XOC_RS17665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XOC_RS17710	COG0745	RESPONSE REGULATOR receiver
XOC_RS17725	COG1404	Belongs to the peptidase S8 family
XOC_RS17740	COG0842	Transport permease protein
XOC_RS17745	COG1131	(ABC) transporter
XOC_RS17750	COG0025	NhaP-type Na H and K H
XOC_RS17755	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XOC_RS17760	COG1573	uracil-dna glycosylase
XOC_RS17770	COG3384	dioxygenase
XOC_RS17785	COG0667	Aldo Keto reductase
XOC_RS17800	COG3590	peptidase
XOC_RS17815	COG3039	Transposase
XOC_RS17820	COG0531	amino acid
XOC_RS17835	COG2972	Histidine kinase
XOC_RS17875	COG1271	oxidase subunit
XOC_RS17880	COG1294	oxidase, subunit
XOC_RS17895	COG1063	alcohol dehydrogenase
XOC_RS17975	COG2963	transposase activity
XOC_RS17995	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XOC_RS18030	COG2353	YceI-like domain
XOC_RS18035	COG2801	Transposase and inactivated derivatives
XOC_RS18085	COG3039	Transposase
XOC_RS18090	COG3210	domain, Protein
XOC_RS18110	COG3210	domain, Protein
XOC_RS18120	COG3210	domain, Protein
XOC_RS18125	COG2831	hemolysin activation secretion protein
XOC_RS18145	COG2963	transposase activity
XOC_RS18150	COG3209	COG3209 Rhs family protein
XOC_RS18155	COG3039	Transposase
XOC_RS18165	COG2826	transposase and inactivated derivatives, IS30 family
XOC_RS18175	COG2951	lytic endotransglycosylase activity
XOC_RS18180	COG2963	transposase activity
XOC_RS18200	COG3039	Transposase
XOC_RS18215	COG0577	efflux transmembrane transporter activity
XOC_RS18255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XOC_RS18265	COG0842	Transport permease protein
XOC_RS18270	COG1131	(ABC) transporter
XOC_RS18275	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XOC_RS18295	COG1476	TRANSCRIPTIONal
XOC_RS18305	COG4555	ABC transporter
XOC_RS18340	COG0625	glutathione transferase activity
XOC_RS18375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XOC_RS18385	COG1560	Kdo2-lipid A biosynthetic process
XOC_RS18430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XOC_RS18430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XOC_RS18435	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XOC_RS18440	COG0242	peptide deformylase activity
XOC_RS18445	COG1652	LysM domain
XOC_RS18450	COG0758	DNA mediated transformation
XOC_RS18470	COG1754	DNA topoisomerase type I activity
XOC_RS18470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XOC_RS18475	COG0009	L-threonylcarbamoyladenylate synthase
XOC_RS18490	COG1028	Short-chain dehydrogenase reductase Sdr
XOC_RS18500	COG0616	signal peptide processing
XOC_RS18505	COG0534	Mate efflux family protein
XOC_RS18525	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XOC_RS18530	COG1324	tolerance protein
XOC_RS18545	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XOC_RS18550	COG0511	ligase activity, forming carbon-carbon bonds
XOC_RS18560	COG0439	Biotin carboxylase
XOC_RS18600	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XOC_RS18615	COG0138	bifunctional purine biosynthesis protein purh
XOC_RS18620	COG0151	Belongs to the GarS family
XOC_RS18625	COG1136	(ABC) transporter
XOC_RS18625	COG0577	efflux transmembrane transporter activity
XOC_RS18635	COG1289	transmembrane transporter activity
XOC_RS18650	COG2814	Major facilitator Superfamily
XOC_RS18665	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XOC_RS18735	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XOC_RS18745	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XOC_RS18755	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XOC_RS18760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XOC_RS18770	COG0134	indole-3-glycerol-phosphate synthase activity
XOC_RS18775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XOC_RS18815	COG0456	acetyltransferase
XOC_RS18825	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XOC_RS18850	COG1192	Involved in chromosome partitioning
XOC_RS18855	COG1475	DNA binding
XOC_RS18870	COG0463	Glycosyl transferase, family 2
XOC_RS18895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XOC_RS18920	COG4221	oxidoreductase activity
XOC_RS18925	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XOC_RS18925	COG2755	lipolytic protein G-D-S-L family
XOC_RS18940	COG1166	arginine decarboxylase activity
XOC_RS18945	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XOC_RS18970	COG2963	transposase activity
XOC_RS19030	COG0606	chelatase, subunit chli
XOC_RS19040	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XOC_RS19085	COG1090	epimerase
XOC_RS19090	COG0642	Histidine kinase
XOC_RS19100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XOC_RS19130	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XOC_RS19140	COG1595	DNA-templated transcription, initiation
XOC_RS19145	COG0753	catalase activity
XOC_RS19185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XOC_RS19190	COG0180	Tryptophanyl-tRNA synthetase
XOC_RS19195	COG3237	CsbD-like
XOC_RS19230	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XOC_RS19235	COG3039	Transposase
XOC_RS19250	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XOC_RS19265	COG3228	Belongs to the MtfA family
XOC_RS19295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XOC_RS19330	COG1199	ATP-dependent helicase activity
XOC_RS19400	COG0702	epimerase
XOC_RS19405	COG1733	regulation of RNA biosynthetic process
XOC_RS19430	COG0583	DNA-binding transcription factor activity
XOC_RS19435	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XOC_RS19445	COG2205	protein histidine kinase activity
XOC_RS19450	COG2205	protein histidine kinase activity
XOC_RS19455	COG0745	RESPONSE REGULATOR receiver
XOC_RS19475	COG1902	pentaerythritol trinitrate reductase activity
XOC_RS19480	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XOC_RS19490	COG2814	Major facilitator Superfamily
XOC_RS19495	COG0583	DNA-binding transcription factor activity
XOC_RS19505	COG0084	hydrolase, TatD family'
XOC_RS19525	COG2826	transposase and inactivated derivatives, IS30 family
XOC_RS19550	COG2963	transposase activity
XOC_RS19595	COG2801	Transposase and inactivated derivatives
XOC_RS19635	COG3039	Transposase
XOC_RS19640	COG2826	transposase and inactivated derivatives, IS30 family
XOC_RS19650	COG0702	epimerase
XOC_RS19675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XOC_RS19695	COG1649	PFAM Uncharacterised BCR, COG1649
XOC_RS19700	COG2354	Protein conserved in bacteria
XOC_RS19705	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XOC_RS19720	COG1511	domain protein
XOC_RS19720	COG3264	Mechanosensitive ion channel
XOC_RS19790	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XOC_RS19890	COG0246	Mannitol dehydrogenase
XOC_RS19895	COG1472	Belongs to the glycosyl hydrolase 3 family
XOC_RS19905	COG4948	Mandelate Racemase Muconate Lactonizing
XOC_RS19915	COG3661	Belongs to the glycosyl hydrolase 67 family
XOC_RS19935	COG2974	May be involved in recombination
XOC_RS19955	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XOC_RS19965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XOC_RS19970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XOC_RS19975	COG0805	protein transport
XOC_RS19985	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XOC_RS19985	COG0519	Catalyzes the synthesis of GMP from XMP
XOC_RS19995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XOC_RS20000	COG0752	glycyl-tRNA synthetase alpha subunit
XOC_RS20010	COG0457	Tetratricopeptide repeat
XOC_RS20025	COG4771	TonB-dependent receptor
XOC_RS20030	COG0729	surface antigen
XOC_RS20035	COG2911	Protein conserved in bacteria
XOC_RS20065	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XOC_RS20070	COG1040	competence protein
XOC_RS20075	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XOC_RS20080	COG0156	8-amino-7-oxononanoate synthase activity
XOC_RS20095	COG1028	Short-chain dehydrogenase reductase Sdr
XOC_RS20120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XOC_RS20160	COG2963	transposase activity
XOC_RS20195	COG0657	acetylesterase activity
XOC_RS20205	COG1414	Transcriptional regulator
XOC_RS20215	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XOC_RS20220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XOC_RS20230	COG3485	protocatechuate 3,4-dioxygenase
XOC_RS20235	COG3485	protocatechuate 3,4-dioxygenase
XOC_RS20245	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XOC_RS20250	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XOC_RS20320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XOC_RS20330	COG0129	dihydroxy-acid dehydratase activity
XOC_RS20335	COG2826	transposase and inactivated derivatives, IS30 family
XOC_RS20365	COG2211	Major facilitator Superfamily
XOC_RS20385	COG3693	PFAM glycoside hydrolase, family 10
XOC_RS20390	COG3693	PFAM glycoside hydrolase, family 10
XOC_RS20425	COG4770	biotin carboxylase activity
XOC_RS20430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XOC_RS20435	COG1960	acyl-CoA dehydrogenase activity
XOC_RS20480	COG0523	cobalamin synthesis protein
XOC_RS20495	COG0697	spore germination
XOC_RS20505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XOC_RS20510	COG1846	Transcriptional regulator
XOC_RS20515	COG1764	response to oxidative stress
XOC_RS20535	COG3293	Transposase
XOC_RS20550	COG0656	L-ascorbic acid biosynthetic process
XOC_RS20555	COG2130	NADP-dependent
XOC_RS20560	COG0667	Aldo Keto reductase
XOC_RS20570	COG1187	pseudouridine synthase activity
XOC_RS20580	COG1643	Atp-dependent helicase
XOC_RS20590	COG4807	Protein conserved in bacteria
XOC_RS20595	COG2351	hydroxyisourate hydrolase activity
XOC_RS20620	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XOC_RS20650	COG3321	synthase
XOC_RS20650	COG0604	alcohol dehydrogenase
XOC_RS20650	COG1028	Short-chain dehydrogenase reductase Sdr
XOC_RS20655	COG2937	Belongs to the GPAT DAPAT family
XOC_RS20685	COG0284	orotidine-5'-phosphate decarboxylase activity
XOC_RS20690	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XOC_RS20705	COG0210	DNA helicase
XOC_RS20720	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XOC_RS20740	COG3039	Transposase
XOC_RS20755	COG0564	pseudouridine synthase activity
XOC_RS20780	COG3706	GGDEF domain
XOC_RS20790	COG1929	Belongs to the glycerate kinase type-1 family
XOC_RS20795	COG2271	Major facilitator Superfamily
XOC_RS20810	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XOC_RS20815	COG0861	Integral membrane protein TerC family
XOC_RS20825	COG0584	glycerophosphoryl diester phosphodiesterase
XOC_RS20835	COG0671	phosphoesterase, PA-phosphatase related
XOC_RS20840	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XOC_RS20845	COG0726	polysaccharide deacetylase
XOC_RS20880	COG2801	Transposase and inactivated derivatives
XOC_RS20895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity