locus-tag	class	description
ACU15_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACU15_RS00020	COG0187	DNA topoisomerase II activity
ACU15_RS00030	COG0501	Belongs to the peptidase M48B family
ACU15_RS00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACU15_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU15_RS00090	COG1064	alcohol dehydrogenase
ACU15_RS00095	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU15_RS00100	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU15_RS00105	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU15_RS00115	COG2234	aminopeptidase activity
ACU15_RS00125	COG4942	peptidase
ACU15_RS00130	COG0793	Belongs to the peptidase S41A family
ACU15_RS00180	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACU15_RS00200	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ACU15_RS00215	COG0210	DNA helicase
ACU15_RS00235	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ACU15_RS00240	COG0284	orotidine-5'-phosphate decarboxylase activity
ACU15_RS00270	COG2937	Belongs to the GPAT DAPAT family
ACU15_RS00275	COG0604	alcohol dehydrogenase
ACU15_RS00275	COG1028	Short-chain dehydrogenase reductase Sdr
ACU15_RS00275	COG3321	synthase
ACU15_RS00320	COG2211	Major facilitator Superfamily
ACU15_RS00340	COG3693	PFAM glycoside hydrolase, family 10
ACU15_RS00345	COG3693	PFAM glycoside hydrolase, family 10
ACU15_RS00380	COG4770	biotin carboxylase activity
ACU15_RS00385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACU15_RS00390	COG1960	acyl-CoA dehydrogenase activity
ACU15_RS00435	COG0523	cobalamin synthesis protein
ACU15_RS00450	COG0697	spore germination
ACU15_RS00460	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ACU15_RS00465	COG1846	Transcriptional regulator
ACU15_RS00470	COG1764	response to oxidative stress
ACU15_RS00485	COG3293	Transposase
ACU15_RS00500	COG0656	L-ascorbic acid biosynthetic process
ACU15_RS00505	COG2130	NADP-dependent
ACU15_RS00510	COG0667	Aldo Keto reductase
ACU15_RS00520	COG1187	pseudouridine synthase activity
ACU15_RS00530	COG1643	Atp-dependent helicase
ACU15_RS00540	COG4807	Protein conserved in bacteria
ACU15_RS00545	COG2351	hydroxyisourate hydrolase activity
ACU15_RS00570	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACU15_RS00590	COG2826	transposase and inactivated derivatives, IS30 family
ACU15_RS00595	COG0129	dihydroxy-acid dehydratase activity
ACU15_RS00605	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ACU15_RS00655	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACU15_RS00675	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACU15_RS00680	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACU15_RS00690	COG3485	protocatechuate 3,4-dioxygenase
ACU15_RS00695	COG3485	protocatechuate 3,4-dioxygenase
ACU15_RS00705	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACU15_RS00710	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACU15_RS00720	COG1414	Transcriptional regulator
ACU15_RS00730	COG0657	acetylesterase activity
ACU15_RS00765	COG2963	transposase activity
ACU15_RS00805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACU15_RS00830	COG1028	Short-chain dehydrogenase reductase Sdr
ACU15_RS00845	COG0156	8-amino-7-oxononanoate synthase activity
ACU15_RS00850	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACU15_RS00855	COG1040	competence protein
ACU15_RS00860	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACU15_RS00895	COG2911	Protein conserved in bacteria
ACU15_RS00900	COG0729	surface antigen
ACU15_RS00905	COG4771	TonB-dependent receptor
ACU15_RS00920	COG0457	Tetratricopeptide repeat
ACU15_RS00930	COG0752	glycyl-tRNA synthetase alpha subunit
ACU15_RS00935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACU15_RS00945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACU15_RS00945	COG0519	Catalyzes the synthesis of GMP from XMP
ACU15_RS00955	COG0805	protein transport
ACU15_RS00960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACU15_RS00965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACU15_RS00975	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACU15_RS00995	COG2974	May be involved in recombination
ACU15_RS01015	COG3661	Belongs to the glycosyl hydrolase 67 family
ACU15_RS01025	COG4948	Mandelate Racemase Muconate Lactonizing
ACU15_RS01035	COG1472	Belongs to the glycosyl hydrolase 3 family
ACU15_RS01040	COG0246	Mannitol dehydrogenase
ACU15_RS01130	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACU15_RS01200	COG3264	Mechanosensitive ion channel
ACU15_RS01200	COG1511	domain protein
ACU15_RS01215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACU15_RS01220	COG2354	Protein conserved in bacteria
ACU15_RS01225	COG1649	PFAM Uncharacterised BCR, COG1649
ACU15_RS01245	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACU15_RS01270	COG0702	epimerase
ACU15_RS01275	COG3039	Transposase
ACU15_RS01280	COG2826	transposase and inactivated derivatives, IS30 family
ACU15_RS01290	COG3039	Transposase
ACU15_RS01305	COG3039	Transposase
ACU15_RS01325	COG2801	Transposase and inactivated derivatives
ACU15_RS01360	COG2963	transposase activity
ACU15_RS01400	COG0084	hydrolase, TatD family'
ACU15_RS01415	COG2814	Major facilitator Superfamily
ACU15_RS01425	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACU15_RS01430	COG1902	pentaerythritol trinitrate reductase activity
ACU15_RS01450	COG0745	RESPONSE REGULATOR receiver
ACU15_RS01455	COG2205	protein histidine kinase activity
ACU15_RS01460	COG2205	protein histidine kinase activity
ACU15_RS01470	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACU15_RS01475	COG0583	DNA-binding transcription factor activity
ACU15_RS01500	COG1733	regulation of RNA biosynthetic process
ACU15_RS01505	COG0702	epimerase
ACU15_RS01540	COG0583	DNA-binding transcription factor activity
ACU15_RS01570	COG1199	ATP-dependent helicase activity
ACU15_RS01580	COG1566	PFAM secretion protein HlyD family protein
ACU15_RS01600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACU15_RS01630	COG3228	Belongs to the MtfA family
ACU15_RS01640	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ACU15_RS01640	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ACU15_RS01645	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ACU15_RS01660	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACU15_RS01695	COG3237	CsbD-like
ACU15_RS01700	COG0180	Tryptophanyl-tRNA synthetase
ACU15_RS01705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACU15_RS01745	COG0753	catalase activity
ACU15_RS01760	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACU15_RS01790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACU15_RS01800	COG0642	Histidine kinase
ACU15_RS01805	COG1090	epimerase
ACU15_RS01840	COG2826	transposase and inactivated derivatives, IS30 family
ACU15_RS01860	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ACU15_RS01870	COG0606	chelatase, subunit chli
ACU15_RS01930	COG2963	transposase activity
ACU15_RS01935	COG2801	Transposase and inactivated derivatives
ACU15_RS01955	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ACU15_RS01960	COG1166	arginine decarboxylase activity
ACU15_RS01980	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACU15_RS01980	COG2755	lipolytic protein G-D-S-L family
ACU15_RS01985	COG4221	oxidoreductase activity
ACU15_RS02010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACU15_RS02035	COG0463	Glycosyl transferase, family 2
ACU15_RS02050	COG1475	DNA binding
ACU15_RS02055	COG1192	Involved in chromosome partitioning
ACU15_RS02085	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ACU15_RS02095	COG0456	acetyltransferase
ACU15_RS02135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACU15_RS02140	COG0134	indole-3-glycerol-phosphate synthase activity
ACU15_RS02150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACU15_RS02155	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ACU15_RS02165	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ACU15_RS02175	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACU15_RS02245	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ACU15_RS02260	COG2814	Major facilitator Superfamily
ACU15_RS02275	COG1289	transmembrane transporter activity
ACU15_RS02285	COG1136	(ABC) transporter
ACU15_RS02285	COG0577	efflux transmembrane transporter activity
ACU15_RS02290	COG0151	Belongs to the GarS family
ACU15_RS02295	COG0138	bifunctional purine biosynthesis protein purh
ACU15_RS02315	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ACU15_RS02350	COG0439	Biotin carboxylase
ACU15_RS02360	COG0511	ligase activity, forming carbon-carbon bonds
ACU15_RS02365	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ACU15_RS02380	COG1324	tolerance protein
ACU15_RS02385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACU15_RS02405	COG0534	Mate efflux family protein
ACU15_RS02410	COG0616	signal peptide processing
ACU15_RS02420	COG1028	Short-chain dehydrogenase reductase Sdr
ACU15_RS02435	COG0009	L-threonylcarbamoyladenylate synthase
ACU15_RS02440	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACU15_RS02440	COG1754	DNA topoisomerase type I activity
ACU15_RS02460	COG0758	DNA mediated transformation
ACU15_RS02470	COG0242	peptide deformylase activity
ACU15_RS02475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACU15_RS02480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACU15_RS02480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACU15_RS02525	COG1560	Kdo2-lipid A biosynthetic process
ACU15_RS02535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACU15_RS02565	COG0625	glutathione transferase activity
ACU15_RS02600	COG4555	ABC transporter
ACU15_RS02610	COG1476	TRANSCRIPTIONal
ACU15_RS02630	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACU15_RS02635	COG1131	(ABC) transporter
ACU15_RS02640	COG0842	Transport permease protein
ACU15_RS02650	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACU15_RS02675	COG3039	Transposase
ACU15_RS02685	COG2951	lytic endotransglycosylase activity
ACU15_RS02700	COG2826	transposase and inactivated derivatives, IS30 family
ACU15_RS02710	COG3039	Transposase
ACU15_RS02715	COG3210	domain, Protein
ACU15_RS02725	COG3210	domain, Protein
ACU15_RS02730	COG3210	domain, Protein
ACU15_RS02760	COG2963	transposase activity
ACU15_RS02765	COG2801	Transposase and inactivated derivatives
ACU15_RS02770	COG2353	YceI-like domain
ACU15_RS02805	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ACU15_RS02865	COG3039	Transposase
ACU15_RS02905	COG1063	alcohol dehydrogenase
ACU15_RS02920	COG1294	oxidase, subunit
ACU15_RS02925	COG1271	oxidase subunit
ACU15_RS02960	COG2972	Histidine kinase
ACU15_RS02975	COG0531	amino acid
ACU15_RS02990	COG3590	peptidase
ACU15_RS03005	COG0667	Aldo Keto reductase
ACU15_RS03020	COG3384	dioxygenase
ACU15_RS03030	COG1573	uracil-dna glycosylase
ACU15_RS03035	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ACU15_RS03040	COG0025	NhaP-type Na H and K H
ACU15_RS03045	COG1131	(ABC) transporter
ACU15_RS03050	COG0842	Transport permease protein
ACU15_RS03065	COG1404	Belongs to the peptidase S8 family
ACU15_RS03080	COG0745	RESPONSE REGULATOR receiver
ACU15_RS03125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU15_RS03150	COG2205	protein histidine kinase activity
ACU15_RS03150	COG2202	Pas domain
ACU15_RS03175	COG2813	Specifically methylates the guanine in position
ACU15_RS03180	COG1187	pseudouridine synthase activity
ACU15_RS03185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACU15_RS03215	COG0697	spore germination
ACU15_RS03225	COG2011	ABC-type metal ion transport system permease component
ACU15_RS03260	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACU15_RS03270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACU15_RS03290	COG0356	it plays a direct role in the translocation of protons across the membrane
ACU15_RS03300	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACU15_RS03310	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACU15_RS03315	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACU15_RS03320	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACU15_RS03345	COG4191	Histidine kinase
ACU15_RS03355	COG0577	efflux transmembrane transporter activity
ACU15_RS03355	COG1136	(ABC) transporter
ACU15_RS03360	COG0577	efflux transmembrane transporter activity
ACU15_RS03360	COG1136	(ABC) transporter
ACU15_RS03375	COG1136	(ABC) transporter
ACU15_RS03380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU15_RS03385	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACU15_RS03435	COG0339	signal peptide processing
ACU15_RS03460	COG0546	phosphoglycolate phosphatase activity
ACU15_RS03470	COG1956	GAF domain-containing protein
ACU15_RS03475	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACU15_RS03485	COG0720	synthase
ACU15_RS03490	COG0513	Belongs to the DEAD box helicase family
ACU15_RS03500	COG0625	glutathione transferase activity
ACU15_RS03530	COG0626	cystathionine gamma-synthase activity
ACU15_RS03545	COG0110	maltose O-acetyltransferase activity
ACU15_RS03550	COG1216	Glycosyl transferase, family 2
ACU15_RS03550	COG0438	transferase activity, transferring glycosyl groups
ACU15_RS03555	COG3754	Rhamnan synthesis protein F
ACU15_RS03585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACU15_RS03600	COG0277	FAD linked oxidase domain protein
ACU15_RS03605	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACU15_RS03605	COG0546	phosphoglycolate phosphatase activity
ACU15_RS03620	COG2086	electron transfer activity
ACU15_RS03645	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ACU15_RS03645	COG0662	Cupin 2, conserved barrel domain protein
ACU15_RS03650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACU15_RS03685	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACU15_RS03685	COG3218	ABC-type transport auxiliary lipoprotein component
ACU15_RS03690	COG1127	ABC transporter
ACU15_RS03695	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACU15_RS03710	COG0442	prolyl-tRNA aminoacylation
ACU15_RS03720	COG1183	phosphatidylcholine synthase activity
ACU15_RS03745	COG0525	valine-tRNA ligase activity
ACU15_RS03760	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACU15_RS03770	COG0795	lipopolysaccharide-transporting ATPase activity
ACU15_RS03785	COG4974	Belongs to the 'phage' integrase family
ACU15_RS03790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACU15_RS03795	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACU15_RS03795	COG0047	phosphoribosylformylglycinamidine synthase activity
ACU15_RS03800	COG5295	Hep Hag repeat protein
ACU15_RS03805	COG1404	Belongs to the peptidase S8 family
ACU15_RS03810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACU15_RS03815	COG1459	type II secretion system
ACU15_RS03820	COG2165	general secretion pathway protein
ACU15_RS03825	COG4970	Tfp pilus assembly protein FimT
ACU15_RS03830	COG2165	general secretion pathway protein
ACU15_RS03835	COG4795	General secretion pathway protein
ACU15_RS03840	COG3156	type II secretion system protein K
ACU15_RS03845	COG3166	PFAM Fimbrial assembly family protein
ACU15_RS03860	COG1450	Type ii and iii secretion system protein
ACU15_RS03875	COG2188	Transcriptional regulator
ACU15_RS03920	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ACU15_RS03930	COG3039	Transposase
ACU15_RS03950	COG0242	peptide deformylase activity
ACU15_RS03970	COG0402	S-adenosylhomocysteine deaminase activity
ACU15_RS03975	COG3964	amidohydrolase
ACU15_RS03995	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACU15_RS04000	COG0726	polysaccharide deacetylase
ACU15_RS04015	COG0436	Aminotransferase
ACU15_RS04045	COG2211	Major facilitator Superfamily
ACU15_RS04050	COG1609	Transcriptional regulator
ACU15_RS04055	COG1028	Short-chain dehydrogenase reductase Sdr
ACU15_RS04060	COG2851	Citrate transporter
ACU15_RS04075	COG0642	Histidine kinase
ACU15_RS04085	COG2197	response regulator
ACU15_RS04110	COG0583	DNA-binding transcription factor activity
ACU15_RS04125	COG4191	Histidine kinase
ACU15_RS04140	COG0281	malic enzyme
ACU15_RS04140	COG0280	phosphate acetyltransferase
ACU15_RS04170	COG1560	Kdo2-lipid A biosynthetic process
ACU15_RS04175	COG1519	Transferase
ACU15_RS04180	COG3039	Transposase
ACU15_RS04185	COG1538	Outer membrane efflux protein
ACU15_RS04190	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACU15_RS04215	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACU15_RS04220	COG0066	3-isopropylmalate dehydratase activity
ACU15_RS04225	COG2226	methyltransferase
ACU15_RS04255	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACU15_RS04260	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACU15_RS04265	COG3710	Transcriptional regulator
ACU15_RS04285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACU15_RS04295	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ACU15_RS04330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACU15_RS04340	COG3781	membrane
ACU15_RS04355	COG1028	Short-chain dehydrogenase reductase Sdr
ACU15_RS04375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACU15_RS04380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACU15_RS04415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACU15_RS04440	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACU15_RS04450	COG0352	thiamine-phosphate diphosphorylase activity
ACU15_RS04455	COG1773	rubredoxin
ACU15_RS04460	COG2912	Transglutaminase-like superfamily
ACU15_RS04480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACU15_RS04500	COG0006	proline dipeptidase activity
ACU15_RS04525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACU15_RS04535	COG0346	lactoylglutathione lyase activity
ACU15_RS04540	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ACU15_RS04545	COG1561	YicC-like family, N-terminal region
ACU15_RS04560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACU15_RS04570	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACU15_RS04595	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACU15_RS04625	COG0714	Associated with various cellular activities
ACU15_RS04645	COG2304	oxidoreductase activity
ACU15_RS04665	COG2801	Transposase and inactivated derivatives
ACU15_RS04670	COG2963	transposase activity
ACU15_RS04675	COG1301	dicarboxylic acid transport
ACU15_RS04680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACU15_RS04690	COG1376	ErfK ybiS ycfS ynhG family protein
ACU15_RS04735	COG1022	Amp-dependent synthetase and ligase
ACU15_RS04780	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ACU15_RS04785	COG4149	molybdate abc transporter
ACU15_RS04790	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACU15_RS04795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACU15_RS04795	COG3453	Protein conserved in bacteria
ACU15_RS04810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACU15_RS04825	COG0126	phosphoglycerate kinase activity
ACU15_RS04835	COG0469	pyruvate kinase activity
ACU15_RS04840	COG3588	fructose-bisphosphate aldolase
ACU15_RS04845	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ACU15_RS04860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACU15_RS04860	COG1648	precorrin-2 dehydrogenase activity
ACU15_RS04875	COG0784	Response regulator, receiver
ACU15_RS04875	COG2205	protein histidine kinase activity
ACU15_RS04875	COG2198	Histidine kinase
ACU15_RS04895	COG0175	sulfate reduction
ACU15_RS04900	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACU15_RS04905	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACU15_RS04910	COG0175	sulfate reduction
ACU15_RS04915	COG2895	sulfate adenylyltransferase (ATP) activity
ACU15_RS04915	COG0529	Catalyzes the synthesis of activated sulfate
ACU15_RS04925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU15_RS04930	COG0308	aminopeptidase N
ACU15_RS04950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACU15_RS04960	COG2963	transposase activity
ACU15_RS04970	COG3328	transposase activity
ACU15_RS04975	COG1970	mechanosensitive ion channel activity
ACU15_RS04995	COG0471	metal ion transport
ACU15_RS04995	COG3273	potassium ion transport
ACU15_RS05005	COG2022	thiamine diphosphate biosynthetic process
ACU15_RS05025	COG3039	Transposase
ACU15_RS05045	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACU15_RS05055	COG2003	Belongs to the UPF0758 family
ACU15_RS05090	COG0084	hydrolase, TatD family'
ACU15_RS05110	COG3039	Transposase
ACU15_RS05175	COG0745	RESPONSE REGULATOR receiver
ACU15_RS05190	COG2963	transposase activity
ACU15_RS05200	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ACU15_RS05210	COG4969	Belongs to the N-Me-Phe pilin family
ACU15_RS05215	COG2194	sulfuric ester hydrolase activity
ACU15_RS05235	COG2184	nucleotidyltransferase activity
ACU15_RS05250	COG0045	succinate-CoA ligase (ADP-forming) activity
ACU15_RS05255	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ACU15_RS05265	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACU15_RS05265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACU15_RS05270	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU15_RS05275	COG0564	pseudouridine synthase activity
ACU15_RS05290	COG3011	Protein conserved in bacteria
ACU15_RS05295	COG0840	transmembrane signaling receptor activity
ACU15_RS05310	COG3387	PFAM Glycoside hydrolase 15-related
ACU15_RS05315	COG1877	trehalose-phosphatase activity
ACU15_RS05345	COG3293	Transposase
ACU15_RS05360	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ACU15_RS05375	COG1595	DNA-templated transcription, initiation
ACU15_RS05385	COG1946	Acyl-CoA thioesterase
ACU15_RS05400	COG0824	Thioesterase
ACU15_RS05405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACU15_RS05415	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ACU15_RS05420	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACU15_RS05425	COG0268	Binds directly to 16S ribosomal RNA
ACU15_RS05430	COG0728	peptidoglycan biosynthetic process
ACU15_RS05435	COG0196	riboflavin kinase activity
ACU15_RS05445	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACU15_RS05450	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACU15_RS05465	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACU15_RS05470	COG1845	cytochrome c oxidase, subunit III
ACU15_RS05475	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ACU15_RS05495	COG3209	COG3209 Rhs family protein
ACU15_RS05510	COG3209	COG3209 Rhs family protein
ACU15_RS05515	COG3328	transposase activity
ACU15_RS05525	COG2826	transposase and inactivated derivatives, IS30 family
ACU15_RS05530	COG3039	Transposase
ACU15_RS05540	COG2801	Transposase and inactivated derivatives
ACU15_RS05545	COG2963	transposase activity
ACU15_RS05570	COG2207	Transcriptional regulator
ACU15_RS05575	COG0326	Molecular chaperone. Has ATPase activity
ACU15_RS05590	COG1366	Belongs to the anti-sigma-factor antagonist family
ACU15_RS05595	COG1366	Belongs to the anti-sigma-factor antagonist family
ACU15_RS05600	COG2172	sigma factor antagonist activity
ACU15_RS05640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACU15_RS05650	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACU15_RS05665	COG2070	2-Nitropropane dioxygenase
ACU15_RS05675	COG0228	four-way junction DNA binding
ACU15_RS05680	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACU15_RS05685	COG0336	Belongs to the RNA methyltransferase TrmD family
ACU15_RS05695	COG0534	Mate efflux family protein
ACU15_RS05705	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ACU15_RS05730	COG0542	response to heat
ACU15_RS05775	COG0019	diaminopimelate decarboxylase activity
ACU15_RS05785	COG2814	Major facilitator Superfamily
ACU15_RS05790	COG4264	IucA IucC family
ACU15_RS05800	COG4772	TonB-dependent receptor
ACU15_RS05815	COG4651	solute:proton antiporter activity
ACU15_RS05815	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACU15_RS05845	COG0488	(ABC) transporter
ACU15_RS05865	COG2755	lipolytic protein G-D-S-L family
ACU15_RS05865	COG0657	acetylesterase activity
ACU15_RS05880	COG0477	Major facilitator Superfamily
ACU15_RS05895	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACU15_RS05930	COG2255	four-way junction helicase activity
ACU15_RS05935	COG0824	Thioesterase
ACU15_RS05955	COG0823	Involved in the tonB-independent uptake of proteins
ACU15_RS05960	COG2885	chlorophyll binding
ACU15_RS05970	COG0602	queuosine metabolic process
ACU15_RS05980	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACU15_RS05995	COG0840	transmembrane signaling receptor activity
ACU15_RS06005	COG1187	pseudouridine synthase activity
ACU15_RS06020	COG0514	ATP-dependent DNA helicase (RecQ)
ACU15_RS06025	COG0783	Belongs to the Dps family
ACU15_RS06030	COG1643	Atp-dependent helicase
ACU15_RS06080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACU15_RS06090	COG1215	transferase activity, transferring glycosyl groups
ACU15_RS06095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACU15_RS06105	COG1199	ATP-dependent helicase activity
ACU15_RS06125	COG0189	ligase activity
ACU15_RS06140	COG0835	chemotaxis
ACU15_RS06145	COG0840	transmembrane signaling receptor activity
ACU15_RS06150	COG0643	Histidine kinase
ACU15_RS06150	COG0784	Response regulator, receiver
ACU15_RS06150	COG2198	Histidine kinase
ACU15_RS06180	COG2304	oxidoreductase activity
ACU15_RS06185	COG1446	asparaginase
ACU15_RS06230	COG3537	Alpha-1,2-mannosidase
ACU15_RS06240	COG2826	transposase and inactivated derivatives, IS30 family
ACU15_RS06250	COG1472	Belongs to the glycosyl hydrolase 3 family
ACU15_RS06260	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ACU15_RS06265	COG1388	LysM domain
ACU15_RS06265	COG3858	chitin binding
ACU15_RS06280	COG0837	glucose binding
ACU15_RS06285	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACU15_RS06295	COG0494	nUDIX hydrolase
ACU15_RS06305	COG3956	TIGRFAM MazG family protein
ACU15_RS06310	COG1742	UPF0060 membrane protein
ACU15_RS06315	COG0330	HflC and HflK could
ACU15_RS06330	COG0509	glycine decarboxylation via glycine cleavage system
ACU15_RS06355	COG1960	acyl-CoA dehydrogenase activity
ACU15_RS06365	COG1309	transcriptional regulator
ACU15_RS06370	COG4771	TonB-dependent receptor
ACU15_RS06380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ACU15_RS06390	COG0463	Glycosyl transferase, family 2
ACU15_RS06395	COG0516	GMP reductase activity
ACU15_RS06395	COG0517	IMP dehydrogenase activity
ACU15_RS06405	COG1272	protein, Hemolysin III
ACU15_RS06415	COG0739	heme binding
ACU15_RS06420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACU15_RS06425	COG0626	cystathionine gamma-synthase activity
ACU15_RS06435	COG1760	l-serine dehydratase
ACU15_RS06465	COG2353	YceI-like domain
ACU15_RS06470	COG2205	protein histidine kinase activity
ACU15_RS06470	COG2198	Histidine kinase
ACU15_RS06470	COG0784	Response regulator, receiver
ACU15_RS06475	COG5002	protein histidine kinase activity
ACU15_RS06475	COG0784	Response regulator, receiver
ACU15_RS06510	COG3250	beta-galactosidase activity
ACU15_RS06535	COG1960	acyl-CoA dehydrogenase activity
ACU15_RS06560	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACU15_RS06560	COG1024	Enoyl-CoA hydratase
ACU15_RS06575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACU15_RS06580	COG0481	GTPase activity
ACU15_RS06585	COG0681	Belongs to the peptidase S26 family
ACU15_RS06605	COG1381	Involved in DNA repair and RecF pathway recombination
ACU15_RS06620	COG2954	triphosphatase activity
ACU15_RS06625	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACU15_RS06635	COG3046	protein related to deoxyribodipyrimidine photolyase
ACU15_RS06645	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ACU15_RS06650	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ACU15_RS06655	COG1278	Cold shock
ACU15_RS06670	COG1201	RNA secondary structure unwinding
ACU15_RS06675	COG1793	dna ligase
ACU15_RS06685	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ACU15_RS06685	COG1793	dna ligase
ACU15_RS06700	COG3706	GGDEF domain
ACU15_RS06715	COG0183	Belongs to the thiolase family
ACU15_RS06730	COG1451	nucleotide metabolic process
ACU15_RS06750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACU15_RS06785	COG1047	Peptidyl-prolyl cis-trans
ACU15_RS06795	COG2824	Alkylphosphonate utilization operon protein PhnA
ACU15_RS06805	COG1902	pentaerythritol trinitrate reductase activity
ACU15_RS06810	COG2814	Major facilitator Superfamily
ACU15_RS06840	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ACU15_RS06840	COG0392	lysyltransferase activity
ACU15_RS06850	COG0251	oxidation-reduction process
ACU15_RS06855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACU15_RS06870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACU15_RS06895	COG1595	DNA-templated transcription, initiation
ACU15_RS06915	COG2878	Part of a membrane complex involved in electron transport
ACU15_RS06925	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACU15_RS06925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACU15_RS06935	COG0346	lactoylglutathione lyase activity
ACU15_RS06940	COG0833	amino acid
ACU15_RS06945	COG2040	homocysteine
ACU15_RS06955	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ACU15_RS06975	COG1695	Transcriptional regulator
ACU15_RS06995	COG1981	membrane
ACU15_RS07010	COG0825	malonyl-CoA metabolic process
ACU15_RS07030	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACU15_RS07035	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACU15_RS07040	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACU15_RS07045	COG3039	Transposase
ACU15_RS07055	COG0750	zinc metalloprotease
ACU15_RS07060	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ACU15_RS07065	COG0575	Belongs to the CDS family
ACU15_RS07075	COG0233	cytoplasmic translational termination
ACU15_RS07090	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACU15_RS07150	COG1393	Belongs to the ArsC family
ACU15_RS07160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACU15_RS07165	COG0367	asparagine synthase
ACU15_RS07175	COG4774	siderophore transport
ACU15_RS07195	COG2207	Transcriptional regulator
ACU15_RS07210	COG1566	PFAM secretion protein HlyD family protein
ACU15_RS07215	COG2814	Major facilitator Superfamily
ACU15_RS07310	COG0386	Belongs to the glutathione peroxidase family
ACU15_RS07365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACU15_RS07370	COG0084	hydrolase, TatD family'
ACU15_RS07385	COG1960	acyl-CoA dehydrogenase activity
ACU15_RS07400	COG0367	asparagine synthase
ACU15_RS07410	COG0305	Participates in initiation and elongation during chromosome replication
ACU15_RS07415	COG0415	Belongs to the DNA photolyase family
ACU15_RS07430	COG1028	Short-chain dehydrogenase reductase Sdr
ACU15_RS07450	COG3706	GGDEF domain
ACU15_RS07460	COG3293	Transposase
ACU15_RS07465	COG0489	protein tyrosine kinase activity
ACU15_RS07470	COG0717	Belongs to the dCTP deaminase family
ACU15_RS07495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACU15_RS07505	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACU15_RS07520	COG0433	COG0433 Predicted ATPase
ACU15_RS07540	COG2890	protein-(glutamine-N5) methyltransferase activity
ACU15_RS07545	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACU15_RS07550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACU15_RS07555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACU15_RS07570	COG0101	tRNA pseudouridine synthase activity
ACU15_RS07575	COG0135	phosphoribosylanthranilate isomerase activity
ACU15_RS07585	COG0133	tryptophan synthase activity
ACU15_RS07600	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ACU15_RS07605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACU15_RS07640	COG0149	triose-phosphate isomerase activity
ACU15_RS07655	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACU15_RS07665	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACU15_RS07670	COG0649	NAD binding
ACU15_RS07675	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ACU15_RS07680	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACU15_RS07685	COG1034	ATP synthesis coupled electron transport
ACU15_RS07690	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACU15_RS07720	COG1007	ATP synthesis coupled electron transport
ACU15_RS07730	COG0779	Required for maturation of 30S ribosomal subunits
ACU15_RS07735	COG0195	Participates in both transcription termination and antitermination
ACU15_RS07740	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACU15_RS07755	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACU15_RS07760	COG1185	polyribonucleotide nucleotidyltransferase activity
ACU15_RS07795	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACU15_RS07805	COG2095	MarC family integral membrane protein
ACU15_RS07815	COG1611	Belongs to the LOG family
ACU15_RS07860	COG2801	Transposase and inactivated derivatives
ACU15_RS07865	COG2963	transposase activity
ACU15_RS07920	COG4974	Belongs to the 'phage' integrase family
ACU15_RS07925	COG4969	Belongs to the N-Me-Phe pilin family
ACU15_RS07930	COG0556	nucleotide-excision repair
ACU15_RS07950	COG3328	transposase activity
ACU15_RS07965	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ACU15_RS07975	COG2986	histidine ammonia-lyase
ACU15_RS07980	COG1228	amidohydrolase
ACU15_RS08020	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACU15_RS08025	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ACU15_RS08030	COG1605	Chorismate mutase
ACU15_RS08030	COG0077	Prephenate dehydratase
ACU15_RS08035	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACU15_RS08050	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACU15_RS08055	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACU15_RS08060	COG0583	DNA-binding transcription factor activity
ACU15_RS08080	COG2801	Transposase and inactivated derivatives
ACU15_RS08085	COG2963	transposase activity
ACU15_RS08110	COG3039	Transposase
ACU15_RS08130	COG2801	Transposase and inactivated derivatives
ACU15_RS08140	COG0840	transmembrane signaling receptor activity
ACU15_RS08155	COG5002	protein histidine kinase activity
ACU15_RS08155	COG2205	protein histidine kinase activity
ACU15_RS08155	COG0784	Response regulator, receiver
ACU15_RS08160	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ACU15_RS08180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACU15_RS08200	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACU15_RS08215	COG1595	DNA-templated transcription, initiation
ACU15_RS08265	COG2244	polysaccharide biosynthetic process
ACU15_RS08295	COG2264	protein methyltransferase activity
ACU15_RS08305	COG0438	transferase activity, transferring glycosyl groups
ACU15_RS08325	COG1132	(ABC) transporter
ACU15_RS08330	COG0477	Major facilitator Superfamily
ACU15_RS08335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACU15_RS08350	COG1253	flavin adenine dinucleotide binding
ACU15_RS08385	COG0504	CTP synthase activity
ACU15_RS08390	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ACU15_RS08400	COG0148	phosphopyruvate hydratase activity
ACU15_RS08405	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ACU15_RS08415	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACU15_RS08430	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACU15_RS08435	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACU15_RS08440	COG1238	metal cluster binding
ACU15_RS08455	COG1534	Rna-binding protein
ACU15_RS08460	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ACU15_RS08470	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACU15_RS08485	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACU15_RS08490	COG1546	Belongs to the CinA family
ACU15_RS08505	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACU15_RS08510	COG2137	regulation of response to DNA damage stimulus
ACU15_RS08515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACU15_RS08520	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ACU15_RS08535	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACU15_RS08560	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACU15_RS08590	COG2166	iron-sulfur cluster assembly
ACU15_RS08605	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACU15_RS08610	COG0137	argininosuccinate synthase activity
ACU15_RS08620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACU15_RS08625	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACU15_RS08640	COG0165	Argininosuccinate lyase
ACU15_RS08685	COG1294	oxidase, subunit
ACU15_RS08690	COG1271	oxidase subunit
ACU15_RS08700	COG4988	ABC transporter
ACU15_RS08705	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ACU15_RS08765	COG4133	protoheme IX ABC transporter activity
ACU15_RS08770	COG0436	Aminotransferase
ACU15_RS08790	COG1187	pseudouridine synthase activity
ACU15_RS08795	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACU15_RS08800	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACU15_RS08805	COG2350	Protein conserved in bacteria
ACU15_RS08835	COG1175	transmembrane transport
ACU15_RS08840	COG0395	ABC-type sugar transport system, permease component
ACU15_RS08860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACU15_RS08865	COG2957	Belongs to the agmatine deiminase family
ACU15_RS08880	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACU15_RS08885	COG0539	negative regulation of cytoplasmic translation
ACU15_RS08890	COG0776	regulation of translation
ACU15_RS08900	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ACU15_RS08905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACU15_RS08915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACU15_RS08920	COG0475	glutathione-regulated potassium exporter activity
ACU15_RS08920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACU15_RS08925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACU15_RS08925	COG0475	glutathione-regulated potassium exporter activity
ACU15_RS08940	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACU15_RS08950	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACU15_RS08950	COG0519	Catalyzes the synthesis of GMP from XMP
ACU15_RS08955	COG3002	Belongs to the UPF0753 family
ACU15_RS08960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACU15_RS08965	COG0583	DNA-binding transcription factor activity
ACU15_RS08985	COG0583	DNA-binding transcription factor activity
ACU15_RS08990	COG0583	DNA-binding transcription factor activity
ACU15_RS09010	COG1914	H( )-stimulated, divalent metal cation uptake system
ACU15_RS09030	COG0668	transmembrane transport
ACU15_RS09055	COG1028	Short-chain dehydrogenase reductase Sdr
ACU15_RS09060	COG1183	phosphatidylcholine synthase activity
ACU15_RS09070	COG3243	poly(R)-hydroxyalkanoic acid synthase
ACU15_RS09085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU15_RS09085	COG0723	plastoquinol--plastocyanin reductase activity
ACU15_RS09095	COG2183	response to ionizing radiation
ACU15_RS09100	COG0784	Response regulator, receiver
ACU15_RS09100	COG2205	protein histidine kinase activity
ACU15_RS09165	COG2963	transposase activity
ACU15_RS09220	COG3039	Transposase
ACU15_RS09225	COG0800	Aldolase
ACU15_RS09230	COG0129	dihydroxy-acid dehydratase activity
ACU15_RS09235	COG0363	glucosamine-6-phosphate deaminase activity
ACU15_RS09245	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACU15_RS09255	COG0354	folic acid binding
ACU15_RS09265	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ACU15_RS09280	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACU15_RS09295	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACU15_RS09320	COG0811	peptide transport
ACU15_RS09335	COG1663	tetraacyldisaccharide 4'-kinase activity
ACU15_RS09345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACU15_RS09355	COG0322	excinuclease ABC activity
ACU15_RS09385	COG2826	transposase and inactivated derivatives, IS30 family
ACU15_RS09400	COG2826	transposase and inactivated derivatives, IS30 family
ACU15_RS09405	COG3039	Transposase
ACU15_RS09440	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACU15_RS09460	COG1054	Belongs to the UPF0176 family
ACU15_RS09470	COG1530	ribonuclease E activity
ACU15_RS09480	COG3064	Membrane
ACU15_RS09495	COG2154	pterin-4-alpha-carbinolamine dehydratase
ACU15_RS09510	COG2963	transposase activity
ACU15_RS09515	COG2801	Transposase and inactivated derivatives
ACU15_RS09610	COG3039	Transposase
ACU15_RS09655	COG0631	protein serine/threonine phosphatase activity
ACU15_RS09660	COG0515	serine threonine protein kinase
ACU15_RS09685	COG1858	cytochrome C peroxidase
ACU15_RS09740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU15_RS09745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU15_RS09755	COG2801	Transposase and inactivated derivatives
ACU15_RS09795	COG2201	protein-glutamate methylesterase activity
ACU15_RS09835	COG4566	intracellular signal transduction
ACU15_RS09845	COG5001	Diguanylate cyclase
ACU15_RS09885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACU15_RS09885	COG1648	precorrin-2 dehydrogenase activity
ACU15_RS09910	COG0746	molybdenum cofactor guanylyltransferase activity
ACU15_RS09945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACU15_RS09955	COG0303	'Molybdopterin
ACU15_RS09960	COG1160	GTP binding
ACU15_RS09965	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU15_RS09985	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACU15_RS10000	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACU15_RS10000	COG1024	Enoyl-CoA hydratase
ACU15_RS10005	COG0183	Belongs to the thiolase family
ACU15_RS10010	COG0038	chloride channel
ACU15_RS10030	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACU15_RS10050	COG1674	ftsk spoiiie
ACU15_RS10055	COG0492	ferredoxin-NADP+ reductase activity
ACU15_RS10085	COG0542	response to heat
ACU15_RS10100	COG0482	sulfurtransferase activity
ACU15_RS10130	COG4585	Histidine kinase
ACU15_RS10140	COG4191	Histidine kinase
ACU15_RS10160	COG0835	chemotaxis
ACU15_RS10160	COG0784	Response regulator, receiver
ACU15_RS10170	COG1558	bacterial-type flagellum-dependent cell motility
ACU15_RS10175	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ACU15_RS10185	COG4787	bacterial-type flagellum-dependent cell motility
ACU15_RS10205	COG1705	Flagellar rod assembly protein muramidase FlgJ
ACU15_RS10205	COG3951	Flagellar rod assembly protein muramidase FlgJ
ACU15_RS10220	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACU15_RS10225	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ACU15_RS10255	COG2201	protein-glutamate methylesterase activity
ACU15_RS10275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACU15_RS10280	COG4221	oxidoreductase activity
ACU15_RS10285	COG1028	Short-chain dehydrogenase reductase Sdr
ACU15_RS10315	COG1677	Flagellar hook-basal body complex protein FliE
ACU15_RS10365	COG3190	flagellar
ACU15_RS10380	COG1684	flagellar biosynthetic protein fliR
ACU15_RS10435	COG2198	Histidine kinase
ACU15_RS10435	COG0784	Response regulator, receiver
ACU15_RS10435	COG0643	Histidine kinase
ACU15_RS10520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACU15_RS10525	COG4774	siderophore transport
ACU15_RS10540	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACU15_RS10545	COG1360	Flagellar Motor Protein
ACU15_RS10550	COG1192	Involved in chromosome partitioning
ACU15_RS10555	COG0835	chemotaxis
ACU15_RS10565	COG0745	RESPONSE REGULATOR receiver
ACU15_RS10575	COG0840	transmembrane signaling receptor activity
ACU15_RS10585	COG0840	transmembrane signaling receptor activity
ACU15_RS10590	COG0840	transmembrane signaling receptor activity
ACU15_RS10595	COG0840	transmembrane signaling receptor activity
ACU15_RS10600	COG0840	transmembrane signaling receptor activity
ACU15_RS10605	COG0840	transmembrane signaling receptor activity
ACU15_RS10610	COG0840	transmembrane signaling receptor activity
ACU15_RS10615	COG0840	transmembrane signaling receptor activity
ACU15_RS10620	COG0840	transmembrane signaling receptor activity
ACU15_RS10625	COG0840	transmembrane signaling receptor activity
ACU15_RS10635	COG0835	chemotaxis
ACU15_RS10645	COG0840	transmembrane signaling receptor activity
ACU15_RS10670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACU15_RS10695	COG0318	PFAM AMP-dependent synthetase and ligase
ACU15_RS10700	COG1024	Enoyl-CoA hydratase
ACU15_RS10705	COG2205	protein histidine kinase activity
ACU15_RS10705	COG2198	Histidine kinase
ACU15_RS10705	COG0784	Response regulator, receiver
ACU15_RS10720	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACU15_RS10725	COG3279	Response regulator of the LytR AlgR family
ACU15_RS10740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACU15_RS10750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACU15_RS10755	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACU15_RS10765	COG0505	Belongs to the CarA family
ACU15_RS10770	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACU15_RS10775	COG2258	MOSC domain
ACU15_RS10780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACU15_RS10830	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACU15_RS10850	COG0277	FAD linked oxidase domain protein
ACU15_RS10855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACU15_RS10865	COG0531	amino acid
ACU15_RS10870	COG0531	amino acid
ACU15_RS10875	COG0235	Class ii aldolase
ACU15_RS10880	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ACU15_RS10900	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACU15_RS10900	COG0140	phosphoribosyl-ATP diphosphatase activity
ACU15_RS10910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACU15_RS10920	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACU15_RS10920	COG0131	Imidazoleglycerol-phosphate dehydratase
ACU15_RS10935	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACU15_RS10945	COG0124	histidyl-tRNA synthetase
ACU15_RS10960	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACU15_RS10975	COG2801	Transposase and inactivated derivatives
ACU15_RS10995	COG2963	transposase activity
ACU15_RS11020	COG1012	belongs to the aldehyde dehydrogenase family
ACU15_RS11040	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACU15_RS11045	COG0697	spore germination
ACU15_RS11050	COG1794	racemase activity, acting on amino acids and derivatives
ACU15_RS11060	COG0671	phosphoesterase, PA-phosphatase related
ACU15_RS11075	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ACU15_RS11080	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU15_RS11085	COG3706	GGDEF domain
ACU15_RS11085	COG2203	Gaf domain
ACU15_RS11085	COG5001	Diguanylate cyclase
ACU15_RS11085	COG4251	negative regulation of phosphorylation
ACU15_RS11095	COG1472	Belongs to the glycosyl hydrolase 3 family
ACU15_RS11120	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ACU15_RS11140	COG0617	tRNA 3'-terminal CCA addition
ACU15_RS11150	COG1469	GTP cyclohydrolase I activity
ACU15_RS11155	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACU15_RS11160	COG0477	Major facilitator Superfamily
ACU15_RS11170	COG1070	Carbohydrate kinase
ACU15_RS11195	COG0800	Aldolase
ACU15_RS11200	COG4948	Mandelate Racemase Muconate Lactonizing
ACU15_RS11210	COG3734	2-keto-3-deoxy-galactonokinase
ACU15_RS11215	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ACU15_RS11225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACU15_RS11240	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACU15_RS11245	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ACU15_RS11255	COG0352	thiamine-phosphate diphosphorylase activity
ACU15_RS11255	COG0351	phosphomethylpyrimidine kinase
ACU15_RS11280	COG0583	DNA-binding transcription factor activity
ACU15_RS11285	COG1741	Belongs to the pirin family
ACU15_RS11325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACU15_RS11330	COG0402	S-adenosylhomocysteine deaminase activity
ACU15_RS11345	COG1509	lysine 2,3-aminomutase activity
ACU15_RS11350	COG5001	Diguanylate cyclase
ACU15_RS11350	COG3300	MHYT domain
ACU15_RS11365	COG0483	inositol monophosphate 1-phosphatase activity
ACU15_RS11370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACU15_RS11390	COG0488	(ABC) transporter
ACU15_RS11395	COG0513	Belongs to the DEAD box helicase family
ACU15_RS11405	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ACU15_RS11415	COG0625	glutathione transferase activity
ACU15_RS11420	COG1278	Cold shock
ACU15_RS11425	COG1671	Belongs to the UPF0178 family
ACU15_RS11430	COG4681	YaeQ
ACU15_RS11435	COG2081	HI0933 family
ACU15_RS11455	COG1028	Short-chain dehydrogenase reductase Sdr
ACU15_RS11475	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACU15_RS11480	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACU15_RS11485	COG0802	atpase or kinase
ACU15_RS11490	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACU15_RS11490	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACU15_RS11495	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACU15_RS11510	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACU15_RS11570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACU15_RS11680	COG0835	chemotaxis
ACU15_RS11685	COG0840	transmembrane signaling receptor activity
ACU15_RS11710	COG2969	positive regulation of protein catabolic process
ACU15_RS11715	COG0625	glutathione transferase activity
ACU15_RS11720	COG2857	Cytochrome c1
ACU15_RS11725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ACU15_RS11730	COG0723	plastoquinol--plastocyanin reductase activity
ACU15_RS11740	COG0741	lytic transglycosylase activity
ACU15_RS11760	COG1702	phosphate starvation-inducible protein PhoH
ACU15_RS11780	COG4535	Mg2 and Co2 transporter CorC
ACU15_RS11795	COG1012	belongs to the aldehyde dehydrogenase family
ACU15_RS11800	COG1177	transmembrane transport
ACU15_RS11805	COG1176	ABC-type spermidine putrescine transport system, permease component I
ACU15_RS11810	COG3842	ATPase activity
ACU15_RS11830	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ACU15_RS11860	COG2201	protein-glutamate methylesterase activity
ACU15_RS11915	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACU15_RS11920	COG0174	glutamine synthetase
ACU15_RS11925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU15_RS11935	COG0477	Major facilitator Superfamily
ACU15_RS11940	COG0243	molybdopterin cofactor binding
ACU15_RS11955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACU15_RS11960	COG1121	(ABC) transporter
ACU15_RS11970	COG2733	membrane
ACU15_RS11975	COG0784	Response regulator, receiver
ACU15_RS11975	COG5002	protein histidine kinase activity
ACU15_RS11975	COG2205	protein histidine kinase activity
ACU15_RS11985	COG0477	Major facilitator Superfamily
ACU15_RS11995	COG2902	Dehydrogenase
ACU15_RS12005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU15_RS12010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU15_RS12020	COG1609	Transcriptional regulator
ACU15_RS12025	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACU15_RS12025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACU15_RS12030	COG1105	Belongs to the carbohydrate kinase PfkB family
ACU15_RS12035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACU15_RS12035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACU15_RS12045	COG3039	Transposase
ACU15_RS12075	COG2963	transposase activity
ACU15_RS12090	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACU15_RS12100	COG1862	Preprotein translocase
ACU15_RS12105	COG0343	queuine tRNA-ribosyltransferase activity
ACU15_RS12160	COG0405	Gamma-glutamyltransferase
ACU15_RS12165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACU15_RS12180	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACU15_RS12185	COG0742	ribosomal rna small subunit methyltransferase
ACU15_RS12190	COG0326	Molecular chaperone. Has ATPase activity
ACU15_RS12230	COG4206	TonB-dependent receptor
ACU15_RS12280	COG0531	amino acid
ACU15_RS12295	COG0006	proline dipeptidase activity
ACU15_RS12305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACU15_RS12320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU15_RS12325	COG3938	Belongs to the proline racemase family
ACU15_RS12335	COG0552	protein localization to endoplasmic reticulum
ACU15_RS12345	COG1194	a g-specific adenine glycosylase
ACU15_RS12355	COG0784	Response regulator, receiver
ACU15_RS12355	COG4191	Histidine kinase
ACU15_RS12360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACU15_RS12385	COG3040	lipid binding
ACU15_RS12395	COG1960	acyl-CoA dehydrogenase activity
ACU15_RS12405	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACU15_RS12435	COG0438	transferase activity, transferring glycosyl groups
ACU15_RS12450	COG0438	transferase activity, transferring glycosyl groups
ACU15_RS12505	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACU15_RS12520	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACU15_RS12530	COG2963	transposase activity
ACU15_RS12545	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ACU15_RS12555	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ACU15_RS12570	COG3115	cell septum assembly
ACU15_RS12590	COG0360	Binds together with S18 to 16S ribosomal RNA
ACU15_RS12595	COG0316	Belongs to the HesB IscA family
ACU15_RS12625	COG0288	reversible hydration of carbon dioxide
ACU15_RS12640	COG3844	kynureninase activity
ACU15_RS12650	COG2925	Exonuclease
ACU15_RS12660	COG0667	Aldo Keto reductase
ACU15_RS12680	COG0116	Belongs to the methyltransferase superfamily
ACU15_RS12680	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACU15_RS12725	COG0494	nUDIX hydrolase
ACU15_RS12735	COG1024	Enoyl-CoA hydratase
ACU15_RS12745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACU15_RS12775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACU15_RS12780	COG0573	inorganic phosphate transmembrane transporter activity
ACU15_RS12795	COG0704	Plays a role in the regulation of phosphate uptake
ACU15_RS12805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACU15_RS12815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACU15_RS12825	COG0557	exoribonuclease II activity
ACU15_RS12845	COG1960	acyl-CoA dehydrogenase activity
ACU15_RS12850	COG2226	methyltransferase
ACU15_RS12870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU15_RS12880	COG1609	Transcriptional regulator
ACU15_RS12895	COG2900	Belongs to the SlyX family
ACU15_RS12910	COG0386	Belongs to the glutathione peroxidase family
ACU15_RS12920	COG1725	Transcriptional regulator
ACU15_RS12925	COG1131	(ABC) transporter
ACU15_RS12985	COG2850	peptidyl-arginine hydroxylation
ACU15_RS13025	COG1132	(ABC) transporter
ACU15_RS13030	COG0583	DNA-binding transcription factor activity
ACU15_RS13065	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ACU15_RS13070	COG0484	heat shock protein binding
ACU15_RS13075	COG0443	Heat shock 70 kDa protein
ACU15_RS13080	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACU15_RS13090	COG0497	DNA recombination
ACU15_RS13100	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU15_RS13105	COG2914	Belongs to the UPF0125 (RnfH) family
ACU15_RS13115	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACU15_RS13130	COG3590	peptidase
ACU15_RS13170	COG2801	Transposase and inactivated derivatives
ACU15_RS13195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU15_RS13200	COG2311	Membrane
ACU15_RS13205	COG1047	Peptidyl-prolyl cis-trans
ACU15_RS13210	COG0791	NLP P60 protein
ACU15_RS13215	COG0791	NLP P60 protein
ACU15_RS13225	COG4106	trans-aconitate 2-methyltransferase activity
ACU15_RS13230	COG1301	dicarboxylic acid transport
ACU15_RS13235	COG1785	Belongs to the alkaline phosphatase family
ACU15_RS13240	COG0037	tRNA processing
ACU15_RS13245	COG1722	exodeoxyribonuclease VII activity
ACU15_RS13250	COG0142	geranyltranstransferase activity
ACU15_RS13255	COG4104	PAAR repeat-containing protein
ACU15_RS13275	COG0312	modulator of DNA gyrase
ACU15_RS13280	COG3028	Belongs to the UPF0307 family
ACU15_RS13285	COG0312	modulator of DNA gyrase
ACU15_RS13295	COG3164	Protein of unknown function
ACU15_RS13310	COG2968	Membrane
ACU15_RS13325	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACU15_RS13350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACU15_RS13375	COG3118	belongs to the thioredoxin family
ACU15_RS13430	COG1132	(ABC) transporter
ACU15_RS13460	COG0745	RESPONSE REGULATOR receiver
ACU15_RS13465	COG5000	phosphorelay sensor kinase activity
ACU15_RS13465	COG5002	protein histidine kinase activity
ACU15_RS13470	COG0475	glutathione-regulated potassium exporter activity
ACU15_RS13480	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACU15_RS13495	COG1187	pseudouridine synthase activity
ACU15_RS13500	COG5001	Diguanylate cyclase
ACU15_RS13500	COG5002	protein histidine kinase activity
ACU15_RS13545	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ACU15_RS13610	COG0735	belongs to the Fur family
ACU15_RS13615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACU15_RS13650	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACU15_RS13660	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACU15_RS13670	COG2198	Histidine kinase
ACU15_RS13670	COG0643	Histidine kinase
ACU15_RS13675	COG0840	transmembrane signaling receptor activity
ACU15_RS13680	COG0835	chemotaxis
ACU15_RS13685	COG2199	diguanylate cyclase activity
ACU15_RS13685	COG2202	Pas domain
ACU15_RS13685	COG2200	EAL domain
ACU15_RS13690	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACU15_RS13775	COG1515	deoxyribonuclease V activity
ACU15_RS13785	COG1741	Belongs to the pirin family
ACU15_RS13855	COG1741	Belongs to the pirin family
ACU15_RS13860	COG1966	Carbon starvation protein
ACU15_RS13865	COG2879	small protein
ACU15_RS13890	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ACU15_RS13895	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACU15_RS13900	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACU15_RS13905	COG2080	2 iron, 2 sulfur cluster binding
ACU15_RS13915	COG1028	Short-chain dehydrogenase reductase Sdr
ACU15_RS13915	COG3321	synthase
ACU15_RS13915	COG0604	alcohol dehydrogenase
ACU15_RS13920	COG2203	Gaf domain
ACU15_RS13920	COG5001	Diguanylate cyclase
ACU15_RS13920	COG4251	negative regulation of phosphorylation
ACU15_RS13920	COG3706	GGDEF domain
ACU15_RS13925	COG0629	single-stranded DNA binding
ACU15_RS13930	COG0142	geranyltranstransferase activity
ACU15_RS13960	COG0527	aspartate kinase activity
ACU15_RS13970	COG0384	phenazine biosynthesis protein PhzF
ACU15_RS13980	COG1764	response to oxidative stress
ACU15_RS13990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACU15_RS13995	COG1678	Uncharacterized ACR, COG1678
ACU15_RS14010	COG0519	Catalyzes the synthesis of GMP from XMP
ACU15_RS14035	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACU15_RS14070	COG0693	protein deglycase activity
ACU15_RS14085	COG1959	2 iron, 2 sulfur cluster binding
ACU15_RS14090	COG0719	Fe-S assembly protein
ACU15_RS14095	COG0396	ATPase activity
ACU15_RS14100	COG0719	Fe-S assembly protein
ACU15_RS14105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACU15_RS14115	COG2146	nitrite reductase [NAD(P)H] activity
ACU15_RS14130	COG1555	photosystem II stabilization
ACU15_RS14135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACU15_RS14150	COG3178	'Phosphotransferase
ACU15_RS14155	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACU15_RS14165	COG0628	permease
ACU15_RS14175	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACU15_RS14190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACU15_RS14210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACU15_RS14215	COG0271	Belongs to the BolA IbaG family
ACU15_RS14225	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACU15_RS14235	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ACU15_RS14240	COG1137	ATPase activity
ACU15_RS14255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACU15_RS14265	COG1660	Displays ATPase and GTPase activities
ACU15_RS14275	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACU15_RS14280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACU15_RS14285	COG2239	Acts as a magnesium transporter
ACU15_RS14295	COG1294	oxidase, subunit
ACU15_RS14300	COG1271	oxidase subunit
ACU15_RS14305	COG1113	amino acid transport
ACU15_RS14315	COG2197	response regulator
ACU15_RS14320	COG0531	amino acid
ACU15_RS14405	COG0754	glutathionylspermidine amidase activity
ACU15_RS14430	COG1842	Phage shock protein A
ACU15_RS14445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACU15_RS14535	COG3039	Transposase
ACU15_RS14685	COG2963	transposase activity
ACU15_RS14835	COG2963	transposase activity
ACU15_RS14840	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ACU15_RS14865	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ACU15_RS14880	COG2197	response regulator
ACU15_RS14885	COG4585	Histidine kinase
ACU15_RS14900	COG2894	cell division
ACU15_RS14905	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ACU15_RS14915	COG0642	Histidine kinase
ACU15_RS14920	COG0745	RESPONSE REGULATOR receiver
ACU15_RS14925	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACU15_RS14935	COG2194	sulfuric ester hydrolase activity
ACU15_RS14970	COG3551	Protein conserved in bacteria
ACU15_RS15005	COG0753	catalase activity
ACU15_RS15025	COG1917	Cupin 2, conserved barrel domain protein
ACU15_RS15025	COG2207	Transcriptional regulator
ACU15_RS15035	COG0823	Involved in the tonB-independent uptake of proteins
ACU15_RS15035	COG1506	peptidase
ACU15_RS15045	COG1297	OPT oligopeptide transporter protein
ACU15_RS15060	COG0587	DNA-directed DNA polymerase activity
ACU15_RS15135	COG0732	type I restriction modification DNA specificity domain
ACU15_RS15170	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ACU15_RS15200	COG1309	transcriptional regulator
ACU15_RS15205	COG1028	Short-chain dehydrogenase reductase Sdr
ACU15_RS15210	COG0308	aminopeptidase N
ACU15_RS15225	COG0330	HflC and HflK could
ACU15_RS15230	COG0330	HflC and HflK could
ACU15_RS15250	COG0678	peroxiredoxin activity
ACU15_RS15295	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACU15_RS15310	COG3829	transcription factor binding
ACU15_RS15320	COG3039	Transposase
ACU15_RS15345	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACU15_RS15350	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACU15_RS15360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACU15_RS15365	COG1028	Short-chain dehydrogenase reductase Sdr
ACU15_RS15390	COG1399	metal-binding, possibly nucleic acid-binding protein
ACU15_RS15410	COG0714	Associated with various cellular activities
ACU15_RS15430	COG0537	adenosine 5'-monophosphoramidase activity
ACU15_RS15440	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACU15_RS15455	COG0314	molybdopterin synthase activity
ACU15_RS15460	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ACU15_RS15465	COG0315	cyclic pyranopterin monophosphate synthase activity
ACU15_RS15475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACU15_RS15480	COG1234	tRNA 3'-trailer cleavage
ACU15_RS15485	COG3642	lipopolysaccharide core region biosynthetic process
ACU15_RS15490	COG0859	PFAM glycosyl transferase family 9
ACU15_RS15505	COG0631	protein serine/threonine phosphatase activity
ACU15_RS15510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACU15_RS15535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACU15_RS15575	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACU15_RS15590	COG2963	transposase activity
ACU15_RS15625	COG0473	3-isopropylmalate dehydrogenase activity
ACU15_RS15640	COG4783	chaperone-mediated protein folding
ACU15_RS15655	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ACU15_RS15665	COG0438	transferase activity, transferring glycosyl groups
ACU15_RS15670	COG0671	phosphoesterase, PA-phosphatase related
ACU15_RS15675	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACU15_RS15685	COG3291	Pkd domain containing protein
ACU15_RS15690	COG2833	Protein of unknown function (DUF455)
ACU15_RS15710	COG0285	dihydrofolate synthase activity
ACU15_RS15715	COG0406	alpha-ribazole phosphatase activity
ACU15_RS15745	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACU15_RS15750	COG4208	sulfate ABC transporter
ACU15_RS15755	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACU15_RS15760	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACU15_RS15765	COG0156	8-amino-7-oxononanoate synthase activity
ACU15_RS15790	COG0604	alcohol dehydrogenase
ACU15_RS15795	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACU15_RS15795	COG1902	pentaerythritol trinitrate reductase activity
ACU15_RS15830	COG0584	glycerophosphoryl diester phosphodiesterase
ACU15_RS15860	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACU15_RS15865	COG1217	gtp-binding protein TYPA
ACU15_RS15885	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ACU15_RS15895	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ACU15_RS15900	COG0203	ribosomal protein L17
ACU15_RS15910	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACU15_RS15915	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACU15_RS15925	COG0201	protein transport
ACU15_RS15930	COG0200	Binds to the 23S rRNA
ACU15_RS15935	COG1841	ribosomal large subunit assembly
ACU15_RS15965	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACU15_RS15970	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACU15_RS15975	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACU15_RS15980	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACU15_RS15985	COG0255	Belongs to the universal ribosomal protein uL29 family
ACU15_RS15990	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACU15_RS16010	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACU15_RS16015	COG0089	rRNA binding
ACU15_RS16020	COG0088	Forms part of the polypeptide exit tunnel
ACU15_RS16030	COG0051	transcription antitermination factor activity, RNA binding
ACU15_RS16050	COG0049	tRNA binding
ACU15_RS16055	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACU15_RS16060	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACU15_RS16065	COG0085	RNA polymerase activity
ACU15_RS16075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACU15_RS16080	COG0081	regulation of translation
ACU15_RS16085	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACU15_RS16090	COG0250	Participates in transcription elongation, termination and antitermination
ACU15_RS16095	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACU15_RS16125	COG0012	GTP binding
ACU15_RS16130	COG0193	aminoacyl-tRNA hydrolase activity
ACU15_RS16140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACU15_RS16155	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ACU15_RS16165	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACU15_RS16170	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACU15_RS16180	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACU15_RS16200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACU15_RS16205	COG1295	ribonuclease BN
ACU15_RS16230	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACU15_RS16240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACU15_RS16280	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACU15_RS16325	COG2890	protein-(glutamine-N5) methyltransferase activity
ACU15_RS16335	COG3634	alkyl hydroperoxide reductase activity
ACU15_RS16340	COG0583	DNA-binding transcription factor activity
ACU15_RS16350	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACU15_RS16355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACU15_RS16365	COG2197	response regulator
ACU15_RS16395	COG0697	spore germination
ACU15_RS16420	COG3386	PFAM SMP-30 Gluconolaconase
ACU15_RS16440	COG1024	Enoyl-CoA hydratase
ACU15_RS16450	COG0318	PFAM AMP-dependent synthetase and ligase
ACU15_RS16455	COG0583	DNA-binding transcription factor activity
ACU15_RS16460	COG3384	dioxygenase
ACU15_RS16490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACU15_RS16495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACU15_RS16505	COG2096	Adenosyltransferase
ACU15_RS16510	COG0123	including yeast histone deacetylase and acetoin utilization protein
ACU15_RS16525	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACU15_RS16530	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACU15_RS16535	COG2967	ApaG domain
ACU15_RS16540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACU15_RS16560	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACU15_RS16580	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACU15_RS16590	COG0642	Histidine kinase
ACU15_RS16605	COG4181	ATPase activity
ACU15_RS16615	COG2175	clavaminate synthase activity
ACU15_RS16650	COG0667	Aldo Keto reductase
ACU15_RS16660	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACU15_RS16665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU15_RS16680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACU15_RS16695	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACU15_RS16730	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACU15_RS16735	COG2226	methyltransferase
ACU15_RS16780	COG1028	Short-chain dehydrogenase reductase Sdr
ACU15_RS16780	COG0604	alcohol dehydrogenase
ACU15_RS16780	COG3321	synthase
ACU15_RS16790	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACU15_RS16800	COG0494	nUDIX hydrolase
ACU15_RS16815	COG4942	peptidase
ACU15_RS16815	COG1388	LysM domain
ACU15_RS16825	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ACU15_RS16840	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACU15_RS16845	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACU15_RS16850	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACU15_RS16865	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACU15_RS16870	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACU15_RS16885	COG3116	cell division
ACU15_RS16890	COG0275	rRNA processing
ACU15_RS16925	COG0792	nuclease activity
ACU15_RS16930	COG1988	membrane-bound metal-dependent
ACU15_RS16935	COG0277	FAD linked oxidase domain protein
ACU15_RS16940	COG0745	RESPONSE REGULATOR receiver
ACU15_RS16945	COG2205	protein histidine kinase activity
ACU15_RS16955	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ACU15_RS16960	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACU15_RS16985	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACU15_RS16990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACU15_RS16995	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACU15_RS17015	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU15_RS17015	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU15_RS17020	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU15_RS17020	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU15_RS17030	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACU15_RS17040	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACU15_RS17060	COG0488	(ABC) transporter
ACU15_RS17085	COG3791	Glutathione-dependent formaldehyde-activating
ACU15_RS17110	COG2205	protein histidine kinase activity
ACU15_RS17130	COG2205	protein histidine kinase activity
ACU15_RS17145	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ACU15_RS17175	COG1012	belongs to the aldehyde dehydrogenase family
ACU15_RS17190	COG2826	transposase and inactivated derivatives, IS30 family
ACU15_RS17200	COG1649	PFAM Uncharacterised BCR, COG1649
ACU15_RS17200	COG0726	polysaccharide deacetylase
ACU15_RS17205	COG1215	transferase activity, transferring glycosyl groups
ACU15_RS17215	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACU15_RS17220	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACU15_RS17225	COG1609	Transcriptional regulator
ACU15_RS17235	COG2188	Transcriptional regulator
ACU15_RS17250	COG3250	beta-galactosidase activity
ACU15_RS17260	COG2801	Transposase and inactivated derivatives
ACU15_RS17275	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACU15_RS17280	COG4191	Histidine kinase
ACU15_RS17285	COG0784	Response regulator, receiver
ACU15_RS17290	COG4251	negative regulation of phosphorylation
ACU15_RS17295	COG2823	Periplasmic or secreted lipoprotein
ACU15_RS17300	COG0673	inositol 2-dehydrogenase activity
ACU15_RS17305	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ACU15_RS17345	COG1056	cytidyltransferase-related domain
ACU15_RS17345	COG1051	belongs to the nudix hydrolase family
ACU15_RS17370	COG2921	Belongs to the UPF0250 family
ACU15_RS17380	COG1686	Belongs to the peptidase S11 family
ACU15_RS17390	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACU15_RS17395	COG2951	lytic endotransglycosylase activity
ACU15_RS17410	COG2963	transposase activity
ACU15_RS17435	COG0772	Belongs to the SEDS family
ACU15_RS17450	COG1792	Involved in formation and maintenance of cell shape
ACU15_RS17455	COG1077	Cell shape determining protein MreB Mrl
ACU15_RS17460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU15_RS17480	COG5001	Diguanylate cyclase
ACU15_RS17480	COG3300	MHYT domain
ACU15_RS17520	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ACU15_RS17540	COG2832	Protein of unknown function (DUF454)
ACU15_RS17550	COG0436	Aminotransferase
ACU15_RS17560	COG1505	serine-type exopeptidase activity
ACU15_RS17585	COG0181	hydroxymethylbilane synthase activity
ACU15_RS17595	COG3275	phosphorelay sensor kinase activity
ACU15_RS17610	COG3039	Transposase
ACU15_RS17625	COG0659	secondary active sulfate transmembrane transporter activity
ACU15_RS17700	COG0598	Magnesium transport protein CorA
ACU15_RS17710	COG1113	amino acid transport
ACU15_RS17735	COG4305	rare lipoprotein A
ACU15_RS17740	COG0697	spore germination
ACU15_RS17790	COG4221	oxidoreductase activity
ACU15_RS17800	COG2801	Transposase and inactivated derivatives
ACU15_RS17805	COG2963	transposase activity
ACU15_RS17820	COG3386	PFAM SMP-30 Gluconolaconase
ACU15_RS17835	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACU15_RS17855	COG0459	protein refolding
ACU15_RS17885	COG1252	NADH dehydrogenase
ACU15_RS17890	COG2860	membrane
ACU15_RS17895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACU15_RS17900	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACU15_RS17905	COG2201	protein-glutamate methylesterase activity
ACU15_RS17910	COG2177	Part of the ABC transporter FtsEX involved in
ACU15_RS17915	COG2884	Cell division ATP-binding protein ftsE
ACU15_RS17925	COG3118	belongs to the thioredoxin family
ACU15_RS17930	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACU15_RS17960	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACU15_RS17960	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACU15_RS17970	COG1473	amidohydrolase
ACU15_RS17975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU15_RS17980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU15_RS18010	COG5383	Protein conserved in bacteria
ACU15_RS18050	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ACU15_RS18055	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACU15_RS18065	COG4948	Mandelate Racemase Muconate Lactonizing
ACU15_RS18075	COG0531	amino acid
ACU15_RS18090	COG4682	membrane
ACU15_RS18100	COG3293	Transposase
ACU15_RS18105	COG2133	pyrroloquinoline quinone binding
ACU15_RS18120	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACU15_RS18125	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACU15_RS18135	COG1610	YqeY-like protein
ACU15_RS18140	COG1295	ribonuclease BN
ACU15_RS18145	COG0358	DNA primase activity
ACU15_RS18195	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ACU15_RS18210	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACU15_RS18235	COG2963	transposase activity
ACU15_RS18270	COG0739	heme binding
ACU15_RS18285	COG2211	Major facilitator Superfamily
ACU15_RS18290	COG0708	Exodeoxyribonuclease III
ACU15_RS18305	COG2963	transposase activity
ACU15_RS18340	COG2111	Na H antiporter
ACU15_RS18340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACU15_RS18345	COG1006	Multisubunit Na H antiporter MnhC subunit
ACU15_RS18350	COG0651	ATP synthesis coupled electron transport
ACU15_RS18360	COG2212	antiporter activity
ACU15_RS18365	COG1320	monovalent cation:proton antiporter activity
ACU15_RS18370	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ACU15_RS18400	COG3104	oligopeptide transport
ACU15_RS18405	COG3483	tryptophan 2,3-dioxygenase activity
ACU15_RS18415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACU15_RS18430	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACU15_RS18440	COG3039	Transposase
ACU15_RS18450	COG0513	Belongs to the DEAD box helicase family
ACU15_RS18500	COG2801	Transposase and inactivated derivatives
ACU15_RS18520	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACU15_RS18525	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACU15_RS18535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACU15_RS18535	COG1042	CoA-binding domain protein
ACU15_RS18535	COG0045	succinate-CoA ligase (ADP-forming) activity
ACU15_RS18545	COG2239	Acts as a magnesium transporter
ACU15_RS18560	COG3039	Transposase
ACU15_RS18575	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACU15_RS18580	COG3387	PFAM Glycoside hydrolase 15-related
ACU15_RS18595	COG3100	YcgL domain-containing protein
ACU15_RS18600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACU15_RS18610	COG0463	Glycosyl transferase, family 2
ACU15_RS18630	COG1028	Short-chain dehydrogenase reductase Sdr
ACU15_RS18670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACU15_RS18685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACU15_RS18725	COG0408	coproporphyrinogen oxidase activity
ACU15_RS18790	COG0210	DNA helicase
ACU15_RS18805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU15_RS18810	COG0583	DNA-binding transcription factor activity
ACU15_RS18815	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACU15_RS18825	COG2159	amidohydrolase
ACU15_RS18850	COG0357	Ribosomal RNA small subunit methyltransferase G
ACU15_RS18855	COG3540	Alkaline phosphatase
ACU15_RS18865	COG2091	lysine biosynthetic process via aminoadipic acid
ACU15_RS18880	COG0708	Exodeoxyribonuclease III
ACU15_RS18890	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACU15_RS18895	COG3162	membrane
ACU15_RS18925	COG0738	Major facilitator superfamily
ACU15_RS18930	COG1414	Transcriptional regulator
ACU15_RS18940	COG2205	protein histidine kinase activity
ACU15_RS18955	COG3459	Glycosyltransferase 36 associated
ACU15_RS18965	COG3265	gluconokinase activity
ACU15_RS18970	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU15_RS18975	COG3039	Transposase
ACU15_RS18990	COG0339	signal peptide processing
ACU15_RS19010	COG0564	pseudouridine synthase activity
ACU15_RS19025	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACU15_RS19040	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACU15_RS19045	COG2826	transposase and inactivated derivatives, IS30 family
ACU15_RS19055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACU15_RS19060	COG0318	PFAM AMP-dependent synthetase and ligase
ACU15_RS19065	COG0727	PFAM Uncharacterised protein family (UPF0153)
ACU15_RS19070	COG0596	Alpha beta hydrolase
ACU15_RS19075	COG3177	Filamentation induced by cAMP protein fic
ACU15_RS19080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACU15_RS19095	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACU15_RS19120	COG4191	Histidine kinase
ACU15_RS19125	COG0028	Belongs to the TPP enzyme family
ACU15_RS19140	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ACU15_RS19145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACU15_RS19185	COG3039	Transposase
ACU15_RS19195	COG0183	Belongs to the thiolase family
ACU15_RS19220	COG3039	Transposase
ACU15_RS19225	COG3039	Transposase
ACU15_RS19250	COG2032	superoxide dismutase activity
ACU15_RS19255	COG2032	superoxide dismutase activity
ACU15_RS19260	COG2204	response regulator
ACU15_RS19265	COG3852	Histidine kinase
ACU15_RS19270	COG0004	ammonium transporteR
ACU15_RS19275	COG0347	Belongs to the P(II) protein family
ACU15_RS19280	COG0174	glutamine synthetase
ACU15_RS19285	COG1968	undecaprenyl-diphosphatase activity
ACU15_RS19330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU15_RS19340	COG2062	phosphohistidine phosphatase, SixA
ACU15_RS19345	COG0489	protein tyrosine kinase activity
ACU15_RS19365	COG1396	sequence-specific DNA binding
ACU15_RS19370	COG3550	peptidyl-serine autophosphorylation
ACU15_RS19375	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ACU15_RS19380	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACU15_RS19395	COG1125	glycine betaine transport
ACU15_RS19395	COG0517	IMP dehydrogenase activity
ACU15_RS19410	COG1119	ATPase activity
ACU15_RS19420	COG1473	amidohydrolase
ACU15_RS19425	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACU15_RS19435	COG1522	sequence-specific DNA binding
ACU15_RS19440	COG3186	Phenylalanine-4-hydroxylase
ACU15_RS19450	COG2755	lipolytic protein G-D-S-L family
ACU15_RS19460	COG1609	Transcriptional regulator
ACU15_RS19480	COG0366	Alpha amylase catalytic
ACU15_RS19485	COG0366	Alpha amylase catalytic
ACU15_RS19495	COG2831	hemolysin activation secretion protein
ACU15_RS19500	COG3210	domain, Protein
ACU15_RS19515	COG2963	transposase activity
ACU15_RS19520	COG2801	Transposase and inactivated derivatives
ACU15_RS19550	COG3135	benzoate transporter
ACU15_RS19570	COG0676	glucose-6-phosphate 1-epimerase activity
ACU15_RS19620	COG0302	gtp cyclohydrolase
ACU15_RS19645	COG0477	Major facilitator Superfamily
ACU15_RS19655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU15_RS19680	COG2963	transposase activity
ACU15_RS19685	COG2801	Transposase and inactivated derivatives
ACU15_RS19715	COG3237	CsbD-like
ACU15_RS19785	COG3039	Transposase
ACU15_RS19790	COG2963	transposase activity
ACU15_RS19795	COG2801	Transposase and inactivated derivatives
ACU15_RS19800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU15_RS19830	COG1755	Isoprenylcysteine carboxyl methyltransferase
ACU15_RS19835	COG1304	FMN binding
ACU15_RS19840	COG3039	Transposase
ACU15_RS19855	COG4772	TonB-dependent receptor
ACU15_RS19865	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ACU15_RS19885	COG1272	protein, Hemolysin III
ACU15_RS19890	COG1111	helicase
ACU15_RS19890	COG1205	dead DEAH box helicase
ACU15_RS19945	COG0067	glutamate synthase
ACU15_RS19945	COG0069	glutamate synthase activity
ACU15_RS19945	COG0070	glutamate synthase
ACU15_RS19950	COG0493	'glutamate synthase
ACU15_RS19965	COG0531	amino acid
ACU15_RS19975	COG1322	Protein conserved in bacteria
ACU15_RS19985	COG0386	Belongs to the glutathione peroxidase family
ACU15_RS19990	COG2853	Lipoprotein
ACU15_RS20005	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACU15_RS20010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACU15_RS20015	COG1127	ABC transporter
ACU15_RS20050	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ACU15_RS20055	COG1074	ATP-dependent DNA helicase activity
ACU15_RS20060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACU15_RS20115	COG2826	transposase and inactivated derivatives, IS30 family
ACU15_RS20135	COG3039	Transposase
ACU15_RS20145	COG2124	cytochrome p450
ACU15_RS20150	COG2124	cytochrome p450
ACU15_RS20155	COG1141	Ferredoxin
ACU15_RS20160	COG1028	Short-chain dehydrogenase reductase Sdr
ACU15_RS20165	COG2124	cytochrome p450
ACU15_RS20170	COG0142	geranyltranstransferase activity
ACU15_RS20175	COG1657	PFAM Prenyltransferase squalene oxidase
ACU15_RS20185	COG1304	FMN binding
ACU15_RS20190	COG2801	Transposase and inactivated derivatives
ACU15_RS20195	COG2963	transposase activity
ACU15_RS20205	COG0564	pseudouridine synthase activity
ACU15_RS20230	COG3706	GGDEF domain
ACU15_RS20240	COG1929	Belongs to the glycerate kinase type-1 family
ACU15_RS20245	COG2271	Major facilitator Superfamily
ACU15_RS20260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACU15_RS20265	COG0861	Integral membrane protein TerC family
ACU15_RS20275	COG0584	glycerophosphoryl diester phosphodiesterase
ACU15_RS20285	COG0671	phosphoesterase, PA-phosphatase related
ACU15_RS20290	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACU15_RS20295	COG0726	polysaccharide deacetylase
ACU15_RS20350	COG0582	viral genome integration into host DNA
ACU15_RS20370	COG2801	Transposase and inactivated derivatives
ACU15_RS20375	COG0732	type I restriction modification DNA specificity domain