locus-tag	class	description
ACU11_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACU11_RS00020	COG0187	DNA topoisomerase II activity
ACU11_RS00030	COG0501	Belongs to the peptidase M48B family
ACU11_RS00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACU11_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU11_RS00145	COG2801	Transposase and inactivated derivatives
ACU11_RS00205	COG0582	viral genome integration into host DNA
ACU11_RS00215	COG1064	alcohol dehydrogenase
ACU11_RS00220	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU11_RS00225	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU11_RS00230	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU11_RS00240	COG2234	aminopeptidase activity
ACU11_RS00250	COG4942	peptidase
ACU11_RS00255	COG0793	Belongs to the peptidase S41A family
ACU11_RS00260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACU11_RS00305	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACU11_RS00315	COG3039	Transposase
ACU11_RS00325	COG3039	Transposase
ACU11_RS00330	COG1304	FMN binding
ACU11_RS00340	COG1657	PFAM Prenyltransferase squalene oxidase
ACU11_RS00345	COG0142	geranyltranstransferase activity
ACU11_RS00350	COG2124	cytochrome p450
ACU11_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
ACU11_RS00360	COG1141	Ferredoxin
ACU11_RS00365	COG2124	cytochrome p450
ACU11_RS00370	COG2124	cytochrome p450
ACU11_RS00450	COG3549	Plasmid maintenance system killer
ACU11_RS00455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACU11_RS00460	COG1074	ATP-dependent DNA helicase activity
ACU11_RS00465	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ACU11_RS00490	COG1127	ABC transporter
ACU11_RS00495	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACU11_RS00500	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACU11_RS00515	COG2853	Lipoprotein
ACU11_RS00520	COG0386	Belongs to the glutathione peroxidase family
ACU11_RS00530	COG1322	Protein conserved in bacteria
ACU11_RS00540	COG0531	amino acid
ACU11_RS00570	COG2826	transposase and inactivated derivatives, IS30 family
ACU11_RS00580	COG0493	'glutamate synthase
ACU11_RS00585	COG0067	glutamate synthase
ACU11_RS00585	COG0069	glutamate synthase activity
ACU11_RS00585	COG0070	glutamate synthase
ACU11_RS00635	COG1111	helicase
ACU11_RS00635	COG1205	dead DEAH box helicase
ACU11_RS00640	COG1272	protein, Hemolysin III
ACU11_RS00660	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ACU11_RS00670	COG4772	TonB-dependent receptor
ACU11_RS00680	COG3039	Transposase
ACU11_RS00685	COG1304	FMN binding
ACU11_RS00690	COG1755	Isoprenylcysteine carboxyl methyltransferase
ACU11_RS00715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU11_RS00730	COG3039	Transposase
ACU11_RS00750	COG0477	Major facilitator Superfamily
ACU11_RS00805	COG3237	CsbD-like
ACU11_RS00830	COG3039	Transposase
ACU11_RS00855	COG0477	Major facilitator Superfamily
ACU11_RS00880	COG0302	gtp cyclohydrolase
ACU11_RS00915	COG0730	response to heat
ACU11_RS00930	COG0676	glucose-6-phosphate 1-epimerase activity
ACU11_RS00950	COG3135	benzoate transporter
ACU11_RS00985	COG2963	transposase activity
ACU11_RS01020	COG3039	Transposase
ACU11_RS01040	COG0366	Alpha amylase catalytic
ACU11_RS01045	COG0366	Alpha amylase catalytic
ACU11_RS01065	COG1609	Transcriptional regulator
ACU11_RS01075	COG1028	Short-chain dehydrogenase reductase Sdr
ACU11_RS01085	COG3186	Phenylalanine-4-hydroxylase
ACU11_RS01090	COG1522	sequence-specific DNA binding
ACU11_RS01095	COG4773	Receptor
ACU11_RS01100	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACU11_RS01105	COG1473	amidohydrolase
ACU11_RS01115	COG1119	ATPase activity
ACU11_RS01130	COG1125	glycine betaine transport
ACU11_RS01130	COG0517	IMP dehydrogenase activity
ACU11_RS01145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACU11_RS01150	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ACU11_RS01155	COG3550	peptidyl-serine autophosphorylation
ACU11_RS01160	COG1396	sequence-specific DNA binding
ACU11_RS01180	COG0489	protein tyrosine kinase activity
ACU11_RS01185	COG2062	phosphohistidine phosphatase, SixA
ACU11_RS01195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU11_RS01240	COG1968	undecaprenyl-diphosphatase activity
ACU11_RS01245	COG0174	glutamine synthetase
ACU11_RS01250	COG0347	Belongs to the P(II) protein family
ACU11_RS01255	COG0004	ammonium transporteR
ACU11_RS01260	COG3852	Histidine kinase
ACU11_RS01265	COG2204	response regulator
ACU11_RS01270	COG2032	superoxide dismutase activity
ACU11_RS01275	COG2032	superoxide dismutase activity
ACU11_RS01290	COG3039	Transposase
ACU11_RS01315	COG0183	Belongs to the thiolase family
ACU11_RS01355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACU11_RS01360	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ACU11_RS01375	COG0028	Belongs to the TPP enzyme family
ACU11_RS01380	COG2205	protein histidine kinase activity
ACU11_RS01405	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACU11_RS01420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACU11_RS01425	COG3177	Filamentation induced by cAMP protein fic
ACU11_RS01430	COG0596	Alpha beta hydrolase
ACU11_RS01435	COG0727	PFAM Uncharacterised protein family (UPF0153)
ACU11_RS01440	COG0318	PFAM AMP-dependent synthetase and ligase
ACU11_RS01445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACU11_RS01460	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACU11_RS01475	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACU11_RS01490	COG0564	pseudouridine synthase activity
ACU11_RS01515	COG0339	signal peptide processing
ACU11_RS01535	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU11_RS01540	COG3265	gluconokinase activity
ACU11_RS01550	COG3459	Glycosyltransferase 36 associated
ACU11_RS01565	COG2205	protein histidine kinase activity
ACU11_RS01575	COG1414	Transcriptional regulator
ACU11_RS01580	COG0738	Major facilitator superfamily
ACU11_RS01610	COG3162	membrane
ACU11_RS01615	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACU11_RS01625	COG0708	Exodeoxyribonuclease III
ACU11_RS01640	COG2091	lysine biosynthetic process via aminoadipic acid
ACU11_RS01650	COG3540	Alkaline phosphatase
ACU11_RS01655	COG0357	Ribosomal RNA small subunit methyltransferase G
ACU11_RS01680	COG2159	amidohydrolase
ACU11_RS01690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACU11_RS01695	COG0583	DNA-binding transcription factor activity
ACU11_RS01700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU11_RS01715	COG0210	DNA helicase
ACU11_RS01785	COG1028	Short-chain dehydrogenase reductase Sdr
ACU11_RS01830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACU11_RS01845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACU11_RS01885	COG0408	coproporphyrinogen oxidase activity
ACU11_RS01900	COG0463	Glycosyl transferase, family 2
ACU11_RS01910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACU11_RS01915	COG3100	YcgL domain-containing protein
ACU11_RS01930	COG3387	PFAM Glycoside hydrolase 15-related
ACU11_RS01935	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACU11_RS01940	COG3039	Transposase
ACU11_RS01965	COG2239	Acts as a magnesium transporter
ACU11_RS01975	COG1042	CoA-binding domain protein
ACU11_RS01975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACU11_RS01975	COG0045	succinate-CoA ligase (ADP-forming) activity
ACU11_RS01985	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACU11_RS01990	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACU11_RS02010	COG2801	Transposase and inactivated derivatives
ACU11_RS02015	COG2963	transposase activity
ACU11_RS02070	COG0513	Belongs to the DEAD box helicase family
ACU11_RS02080	COG3039	Transposase
ACU11_RS02095	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACU11_RS02110	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACU11_RS02120	COG3483	tryptophan 2,3-dioxygenase activity
ACU11_RS02125	COG3104	oligopeptide transport
ACU11_RS02155	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ACU11_RS02160	COG1320	monovalent cation:proton antiporter activity
ACU11_RS02165	COG2212	antiporter activity
ACU11_RS02175	COG0651	ATP synthesis coupled electron transport
ACU11_RS02180	COG1006	Multisubunit Na H antiporter MnhC subunit
ACU11_RS02185	COG2111	Na H antiporter
ACU11_RS02185	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACU11_RS02225	COG0708	Exodeoxyribonuclease III
ACU11_RS02230	COG2211	Major facilitator Superfamily
ACU11_RS02250	COG0739	heme binding
ACU11_RS02285	COG2963	transposase activity
ACU11_RS02310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACU11_RS02325	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ACU11_RS02375	COG0358	DNA primase activity
ACU11_RS02380	COG1295	ribonuclease BN
ACU11_RS02385	COG1610	YqeY-like protein
ACU11_RS02395	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACU11_RS02400	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACU11_RS02415	COG2133	pyrroloquinoline quinone binding
ACU11_RS02420	COG4682	membrane
ACU11_RS02435	COG0531	amino acid
ACU11_RS02445	COG4948	Mandelate Racemase Muconate Lactonizing
ACU11_RS02455	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACU11_RS02460	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ACU11_RS02500	COG5383	Protein conserved in bacteria
ACU11_RS02530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU11_RS02535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU11_RS02540	COG1473	amidohydrolase
ACU11_RS02550	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACU11_RS02550	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACU11_RS02580	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACU11_RS02585	COG3118	belongs to the thioredoxin family
ACU11_RS02595	COG2884	Cell division ATP-binding protein ftsE
ACU11_RS02600	COG2177	Part of the ABC transporter FtsEX involved in
ACU11_RS02605	COG2201	protein-glutamate methylesterase activity
ACU11_RS02610	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACU11_RS02615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACU11_RS02620	COG2860	membrane
ACU11_RS02625	COG1252	NADH dehydrogenase
ACU11_RS02655	COG0459	protein refolding
ACU11_RS02670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACU11_RS02685	COG3386	PFAM SMP-30 Gluconolaconase
ACU11_RS02690	COG2963	transposase activity
ACU11_RS02705	COG4221	oxidoreductase activity
ACU11_RS02750	COG0697	spore germination
ACU11_RS02755	COG4305	rare lipoprotein A
ACU11_RS02785	COG1113	amino acid transport
ACU11_RS02795	COG0598	Magnesium transport protein CorA
ACU11_RS02865	COG0659	secondary active sulfate transmembrane transporter activity
ACU11_RS02890	COG3275	phosphorelay sensor kinase activity
ACU11_RS02900	COG0181	hydroxymethylbilane synthase activity
ACU11_RS02925	COG1505	serine-type exopeptidase activity
ACU11_RS02935	COG0436	Aminotransferase
ACU11_RS02945	COG2832	Protein of unknown function (DUF454)
ACU11_RS02965	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ACU11_RS03005	COG5001	Diguanylate cyclase
ACU11_RS03005	COG3300	MHYT domain
ACU11_RS03025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU11_RS03030	COG1077	Cell shape determining protein MreB Mrl
ACU11_RS03060	COG0772	Belongs to the SEDS family
ACU11_RS03075	COG2951	lytic endotransglycosylase activity
ACU11_RS03080	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACU11_RS03090	COG1686	Belongs to the peptidase S11 family
ACU11_RS03100	COG2921	Belongs to the UPF0250 family
ACU11_RS03125	COG1051	belongs to the nudix hydrolase family
ACU11_RS03125	COG1056	cytidyltransferase-related domain
ACU11_RS03165	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ACU11_RS03175	COG0673	inositol 2-dehydrogenase activity
ACU11_RS03180	COG2823	Periplasmic or secreted lipoprotein
ACU11_RS03185	COG4251	negative regulation of phosphorylation
ACU11_RS03190	COG0784	Response regulator, receiver
ACU11_RS03195	COG4191	Histidine kinase
ACU11_RS03200	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACU11_RS03215	COG2801	Transposase and inactivated derivatives
ACU11_RS03230	COG3250	beta-galactosidase activity
ACU11_RS03245	COG2188	Transcriptional regulator
ACU11_RS03255	COG1609	Transcriptional regulator
ACU11_RS03260	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACU11_RS03265	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACU11_RS03275	COG1215	transferase activity, transferring glycosyl groups
ACU11_RS03280	COG0726	polysaccharide deacetylase
ACU11_RS03280	COG1649	PFAM Uncharacterised BCR, COG1649
ACU11_RS03290	COG2826	transposase and inactivated derivatives, IS30 family
ACU11_RS03305	COG1012	belongs to the aldehyde dehydrogenase family
ACU11_RS03335	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ACU11_RS03360	COG2205	protein histidine kinase activity
ACU11_RS03375	COG3039	Transposase
ACU11_RS03385	COG2205	protein histidine kinase activity
ACU11_RS03410	COG3791	Glutathione-dependent formaldehyde-activating
ACU11_RS03435	COG0488	(ABC) transporter
ACU11_RS03455	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACU11_RS03465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACU11_RS03475	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU11_RS03475	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU11_RS03480	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU11_RS03480	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU11_RS03500	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACU11_RS03505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACU11_RS03510	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACU11_RS03535	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACU11_RS03540	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ACU11_RS03550	COG2205	protein histidine kinase activity
ACU11_RS03555	COG0745	RESPONSE REGULATOR receiver
ACU11_RS03560	COG0277	FAD linked oxidase domain protein
ACU11_RS03565	COG1988	membrane-bound metal-dependent
ACU11_RS03570	COG0792	nuclease activity
ACU11_RS03605	COG0275	rRNA processing
ACU11_RS03610	COG3116	cell division
ACU11_RS03625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACU11_RS03630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACU11_RS03645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACU11_RS03650	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACU11_RS03655	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACU11_RS03670	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ACU11_RS03680	COG1388	LysM domain
ACU11_RS03680	COG4942	peptidase
ACU11_RS03695	COG0494	nUDIX hydrolase
ACU11_RS03705	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACU11_RS03715	COG3321	synthase
ACU11_RS03715	COG1028	Short-chain dehydrogenase reductase Sdr
ACU11_RS03715	COG0604	alcohol dehydrogenase
ACU11_RS03760	COG2226	methyltransferase
ACU11_RS03765	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACU11_RS03800	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACU11_RS03815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACU11_RS03830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU11_RS03835	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACU11_RS03850	COG0667	Aldo Keto reductase
ACU11_RS03885	COG2175	clavaminate synthase activity
ACU11_RS03895	COG4181	ATPase activity
ACU11_RS03910	COG0642	Histidine kinase
ACU11_RS03920	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACU11_RS03940	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACU11_RS03960	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACU11_RS03965	COG2967	ApaG domain
ACU11_RS03970	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACU11_RS03975	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACU11_RS03990	COG0123	including yeast histone deacetylase and acetoin utilization protein
ACU11_RS03995	COG2096	Adenosyltransferase
ACU11_RS04005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACU11_RS04010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACU11_RS04040	COG3384	dioxygenase
ACU11_RS04045	COG0583	DNA-binding transcription factor activity
ACU11_RS04050	COG0318	PFAM AMP-dependent synthetase and ligase
ACU11_RS04060	COG1024	Enoyl-CoA hydratase
ACU11_RS04080	COG3386	PFAM SMP-30 Gluconolaconase
ACU11_RS04105	COG0697	spore germination
ACU11_RS04135	COG2197	response regulator
ACU11_RS04145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACU11_RS04150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACU11_RS04160	COG0583	DNA-binding transcription factor activity
ACU11_RS04165	COG3634	alkyl hydroperoxide reductase activity
ACU11_RS04175	COG2890	protein-(glutamine-N5) methyltransferase activity
ACU11_RS04220	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACU11_RS04260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACU11_RS04265	COG1404	Belongs to the peptidase S8 family
ACU11_RS04270	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACU11_RS04295	COG1295	ribonuclease BN
ACU11_RS04300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACU11_RS04320	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACU11_RS04330	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACU11_RS04335	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACU11_RS04345	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ACU11_RS04360	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACU11_RS04370	COG0193	aminoacyl-tRNA hydrolase activity
ACU11_RS04375	COG0012	GTP binding
ACU11_RS04405	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACU11_RS04410	COG0250	Participates in transcription elongation, termination and antitermination
ACU11_RS04415	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACU11_RS04420	COG0081	regulation of translation
ACU11_RS04425	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACU11_RS04435	COG0085	RNA polymerase activity
ACU11_RS04440	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACU11_RS04445	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACU11_RS04450	COG0049	tRNA binding
ACU11_RS04470	COG0051	transcription antitermination factor activity, RNA binding
ACU11_RS04480	COG0088	Forms part of the polypeptide exit tunnel
ACU11_RS04485	COG0089	rRNA binding
ACU11_RS04490	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACU11_RS04510	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACU11_RS04515	COG0255	Belongs to the universal ribosomal protein uL29 family
ACU11_RS04520	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACU11_RS04525	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACU11_RS04530	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACU11_RS04535	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACU11_RS04565	COG1841	ribosomal large subunit assembly
ACU11_RS04570	COG0200	Binds to the 23S rRNA
ACU11_RS04575	COG0201	protein transport
ACU11_RS04585	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACU11_RS04590	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACU11_RS04600	COG0203	ribosomal protein L17
ACU11_RS04605	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ACU11_RS04620	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ACU11_RS04640	COG1217	gtp-binding protein TYPA
ACU11_RS04645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACU11_RS04675	COG3039	Transposase
ACU11_RS04685	COG0584	glycerophosphoryl diester phosphodiesterase
ACU11_RS04705	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACU11_RS04705	COG1902	pentaerythritol trinitrate reductase activity
ACU11_RS04710	COG0604	alcohol dehydrogenase
ACU11_RS04735	COG0156	8-amino-7-oxononanoate synthase activity
ACU11_RS04740	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACU11_RS04745	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACU11_RS04750	COG4208	sulfate ABC transporter
ACU11_RS04755	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACU11_RS04790	COG0406	alpha-ribazole phosphatase activity
ACU11_RS04795	COG0285	dihydrofolate synthase activity
ACU11_RS04815	COG2833	Protein of unknown function (DUF455)
ACU11_RS04825	COG3291	Pkd domain containing protein
ACU11_RS04835	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACU11_RS04840	COG0671	phosphoesterase, PA-phosphatase related
ACU11_RS04845	COG0438	transferase activity, transferring glycosyl groups
ACU11_RS04855	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ACU11_RS04870	COG4783	chaperone-mediated protein folding
ACU11_RS04885	COG0473	3-isopropylmalate dehydrogenase activity
ACU11_RS04915	COG2801	Transposase and inactivated derivatives
ACU11_RS04920	COG2963	transposase activity
ACU11_RS04935	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACU11_RS04975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACU11_RS05000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACU11_RS05005	COG0631	protein serine/threonine phosphatase activity
ACU11_RS05110	COG1802	Transcriptional regulator
ACU11_RS05110	COG4626	Terminase
ACU11_RS05115	COG4695	Portal protein
ACU11_RS05120	COG0740	serine-type endopeptidase activity
ACU11_RS05245	COG0582	viral genome integration into host DNA
ACU11_RS05255	COG0859	PFAM glycosyl transferase family 9
ACU11_RS05260	COG3642	lipopolysaccharide core region biosynthetic process
ACU11_RS05265	COG1234	tRNA 3'-trailer cleavage
ACU11_RS05270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACU11_RS05280	COG0315	cyclic pyranopterin monophosphate synthase activity
ACU11_RS05285	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ACU11_RS05290	COG0314	molybdopterin synthase activity
ACU11_RS05305	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACU11_RS05315	COG0537	adenosine 5'-monophosphoramidase activity
ACU11_RS05335	COG0714	Associated with various cellular activities
ACU11_RS05355	COG1399	metal-binding, possibly nucleic acid-binding protein
ACU11_RS05380	COG1028	Short-chain dehydrogenase reductase Sdr
ACU11_RS05385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACU11_RS05395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACU11_RS05400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACU11_RS05430	COG3829	transcription factor binding
ACU11_RS05445	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACU11_RS05490	COG0678	peroxiredoxin activity
ACU11_RS05510	COG0330	HflC and HflK could
ACU11_RS05515	COG0330	HflC and HflK could
ACU11_RS05530	COG0308	aminopeptidase N
ACU11_RS05540	COG1028	Short-chain dehydrogenase reductase Sdr
ACU11_RS05545	COG1309	transcriptional regulator
ACU11_RS05575	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ACU11_RS05685	COG0587	DNA-directed DNA polymerase activity
ACU11_RS05700	COG1297	OPT oligopeptide transporter protein
ACU11_RS05715	COG1506	peptidase
ACU11_RS05715	COG0823	Involved in the tonB-independent uptake of proteins
ACU11_RS05725	COG1917	Cupin 2, conserved barrel domain protein
ACU11_RS05725	COG2207	Transcriptional regulator
ACU11_RS05745	COG0753	catalase activity
ACU11_RS05775	COG3551	Protein conserved in bacteria
ACU11_RS05810	COG2194	sulfuric ester hydrolase activity
ACU11_RS05820	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACU11_RS05825	COG0745	RESPONSE REGULATOR receiver
ACU11_RS05830	COG0642	Histidine kinase
ACU11_RS05840	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ACU11_RS05845	COG2894	cell division
ACU11_RS05860	COG4585	Histidine kinase
ACU11_RS05865	COG2197	response regulator
ACU11_RS05880	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ACU11_RS05910	COG2963	transposase activity
ACU11_RS06070	COG3039	Transposase
ACU11_RS06075	COG3179	chitinase
ACU11_RS06115	COG2801	Transposase and inactivated derivatives
ACU11_RS06120	COG2963	transposase activity
ACU11_RS06330	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACU11_RS06345	COG1842	Phage shock protein A
ACU11_RS06370	COG0754	glutathionylspermidine amidase activity
ACU11_RS06455	COG0531	amino acid
ACU11_RS06460	COG2197	response regulator
ACU11_RS06465	COG2267	carboxylic ester hydrolase activity
ACU11_RS06470	COG1113	amino acid transport
ACU11_RS06475	COG1271	oxidase subunit
ACU11_RS06480	COG1294	oxidase, subunit
ACU11_RS06490	COG2239	Acts as a magnesium transporter
ACU11_RS06495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACU11_RS06500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACU11_RS06510	COG1660	Displays ATPase and GTPase activities
ACU11_RS06520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACU11_RS06535	COG1137	ATPase activity
ACU11_RS06540	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ACU11_RS06550	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACU11_RS06560	COG0271	Belongs to the BolA IbaG family
ACU11_RS06565	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACU11_RS06585	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACU11_RS06600	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACU11_RS06610	COG0628	permease
ACU11_RS06620	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACU11_RS06625	COG3178	'Phosphotransferase
ACU11_RS06650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACU11_RS06655	COG1555	photosystem II stabilization
ACU11_RS06670	COG3039	Transposase
ACU11_RS06675	COG2146	nitrite reductase [NAD(P)H] activity
ACU11_RS06685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACU11_RS06690	COG0719	Fe-S assembly protein
ACU11_RS06695	COG0396	ATPase activity
ACU11_RS06700	COG0719	Fe-S assembly protein
ACU11_RS06705	COG1959	2 iron, 2 sulfur cluster binding
ACU11_RS06755	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACU11_RS06780	COG0519	Catalyzes the synthesis of GMP from XMP
ACU11_RS06795	COG1678	Uncharacterized ACR, COG1678
ACU11_RS06800	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACU11_RS06810	COG1764	response to oxidative stress
ACU11_RS06820	COG0384	phenazine biosynthesis protein PhzF
ACU11_RS06830	COG0527	aspartate kinase activity
ACU11_RS06870	COG0142	geranyltranstransferase activity
ACU11_RS06875	COG0629	single-stranded DNA binding
ACU11_RS06880	COG2203	Gaf domain
ACU11_RS06880	COG5001	Diguanylate cyclase
ACU11_RS06880	COG3706	GGDEF domain
ACU11_RS06880	COG4251	negative regulation of phosphorylation
ACU11_RS06885	COG3321	synthase
ACU11_RS06885	COG1028	Short-chain dehydrogenase reductase Sdr
ACU11_RS06885	COG0604	alcohol dehydrogenase
ACU11_RS06895	COG2080	2 iron, 2 sulfur cluster binding
ACU11_RS06900	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACU11_RS06905	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACU11_RS06935	COG2879	small protein
ACU11_RS06940	COG1966	Carbon starvation protein
ACU11_RS06945	COG1741	Belongs to the pirin family
ACU11_RS07020	COG1741	Belongs to the pirin family
ACU11_RS07030	COG1515	deoxyribonuclease V activity
ACU11_RS07040	COG2801	Transposase and inactivated derivatives
ACU11_RS07045	COG2963	transposase activity
ACU11_RS07145	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACU11_RS07150	COG2202	Pas domain
ACU11_RS07150	COG2200	EAL domain
ACU11_RS07150	COG2199	diguanylate cyclase activity
ACU11_RS07155	COG0835	chemotaxis
ACU11_RS07160	COG0840	transmembrane signaling receptor activity
ACU11_RS07165	COG2198	Histidine kinase
ACU11_RS07165	COG0643	Histidine kinase
ACU11_RS07175	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACU11_RS07185	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACU11_RS07190	COG2205	protein histidine kinase activity
ACU11_RS07220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACU11_RS07225	COG0735	belongs to the Fur family
ACU11_RS07340	COG5001	Diguanylate cyclase
ACU11_RS07340	COG5002	protein histidine kinase activity
ACU11_RS07345	COG1187	pseudouridine synthase activity
ACU11_RS07360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACU11_RS07370	COG0475	glutathione-regulated potassium exporter activity
ACU11_RS07375	COG5002	protein histidine kinase activity
ACU11_RS07375	COG5000	phosphorelay sensor kinase activity
ACU11_RS07380	COG0745	RESPONSE REGULATOR receiver
ACU11_RS07385	COG1538	Outer membrane efflux protein
ACU11_RS07410	COG1132	(ABC) transporter
ACU11_RS07430	COG2826	transposase and inactivated derivatives, IS30 family
ACU11_RS07470	COG3118	belongs to the thioredoxin family
ACU11_RS07495	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACU11_RS07515	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACU11_RS07530	COG2968	Membrane
ACU11_RS07545	COG3164	Protein of unknown function
ACU11_RS07555	COG0312	modulator of DNA gyrase
ACU11_RS07560	COG3028	Belongs to the UPF0307 family
ACU11_RS07565	COG0312	modulator of DNA gyrase
ACU11_RS07585	COG4104	PAAR repeat-containing protein
ACU11_RS07590	COG0142	geranyltranstransferase activity
ACU11_RS07595	COG1722	exodeoxyribonuclease VII activity
ACU11_RS07600	COG0037	tRNA processing
ACU11_RS07605	COG1785	Belongs to the alkaline phosphatase family
ACU11_RS07610	COG1301	dicarboxylic acid transport
ACU11_RS07625	COG0791	NLP P60 protein
ACU11_RS07630	COG0791	NLP P60 protein
ACU11_RS07635	COG1047	Peptidyl-prolyl cis-trans
ACU11_RS07640	COG2311	Membrane
ACU11_RS07645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU11_RS07665	COG2963	transposase activity
ACU11_RS07670	COG2801	Transposase and inactivated derivatives
ACU11_RS07680	COG2801	Transposase and inactivated derivatives
ACU11_RS07700	COG2801	Transposase and inactivated derivatives
ACU11_RS07735	COG3590	peptidase
ACU11_RS07755	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACU11_RS07765	COG2914	Belongs to the UPF0125 (RnfH) family
ACU11_RS07770	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU11_RS07780	COG0497	DNA recombination
ACU11_RS07790	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACU11_RS07795	COG0443	Heat shock 70 kDa protein
ACU11_RS07800	COG0484	heat shock protein binding
ACU11_RS07805	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ACU11_RS07820	COG0583	DNA-binding transcription factor activity
ACU11_RS07825	COG1132	(ABC) transporter
ACU11_RS07860	COG2850	peptidyl-arginine hydroxylation
ACU11_RS07920	COG1131	(ABC) transporter
ACU11_RS07925	COG1725	Transcriptional regulator
ACU11_RS07935	COG0386	Belongs to the glutathione peroxidase family
ACU11_RS07950	COG2900	Belongs to the SlyX family
ACU11_RS07965	COG1609	Transcriptional regulator
ACU11_RS07975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU11_RS07995	COG2226	methyltransferase
ACU11_RS08000	COG1960	acyl-CoA dehydrogenase activity
ACU11_RS08020	COG0557	exoribonuclease II activity
ACU11_RS08030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACU11_RS08040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACU11_RS08050	COG0704	Plays a role in the regulation of phosphate uptake
ACU11_RS08065	COG0573	inorganic phosphate transmembrane transporter activity
ACU11_RS08070	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACU11_RS08095	COG0659	secondary active sulfate transmembrane transporter activity
ACU11_RS08100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACU11_RS08110	COG1024	Enoyl-CoA hydratase
ACU11_RS08120	COG0494	nUDIX hydrolase
ACU11_RS08165	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACU11_RS08165	COG0116	Belongs to the methyltransferase superfamily
ACU11_RS08170	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACU11_RS08185	COG0667	Aldo Keto reductase
ACU11_RS08195	COG2925	Exonuclease
ACU11_RS08205	COG3844	kynureninase activity
ACU11_RS08220	COG0288	reversible hydration of carbon dioxide
ACU11_RS08250	COG0316	Belongs to the HesB IscA family
ACU11_RS08255	COG0360	Binds together with S18 to 16S ribosomal RNA
ACU11_RS08275	COG3115	cell septum assembly
ACU11_RS08290	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ACU11_RS08300	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ACU11_RS08320	COG2801	Transposase and inactivated derivatives
ACU11_RS08325	COG2963	transposase activity
ACU11_RS08335	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACU11_RS08350	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACU11_RS08405	COG0438	transferase activity, transferring glycosyl groups
ACU11_RS08410	COG0438	transferase activity, transferring glycosyl groups
ACU11_RS08420	COG0438	transferase activity, transferring glycosyl groups
ACU11_RS08450	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACU11_RS08460	COG1960	acyl-CoA dehydrogenase activity
ACU11_RS08470	COG3040	lipid binding
ACU11_RS08495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACU11_RS08500	COG4191	Histidine kinase
ACU11_RS08500	COG0784	Response regulator, receiver
ACU11_RS08510	COG1194	a g-specific adenine glycosylase
ACU11_RS08520	COG0552	protein localization to endoplasmic reticulum
ACU11_RS08530	COG3938	Belongs to the proline racemase family
ACU11_RS08535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU11_RS08550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACU11_RS08560	COG0006	proline dipeptidase activity
ACU11_RS08575	COG0531	amino acid
ACU11_RS08625	COG4206	TonB-dependent receptor
ACU11_RS08640	COG1506	peptidase
ACU11_RS08640	COG0823	Involved in the tonB-independent uptake of proteins
ACU11_RS08670	COG0326	Molecular chaperone. Has ATPase activity
ACU11_RS08675	COG0742	ribosomal rna small subunit methyltransferase
ACU11_RS08680	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACU11_RS08695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACU11_RS08750	COG0343	queuine tRNA-ribosyltransferase activity
ACU11_RS08755	COG1862	Preprotein translocase
ACU11_RS08760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACU11_RS08765	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACU11_RS08780	COG2963	transposase activity
ACU11_RS08785	COG2801	Transposase and inactivated derivatives
ACU11_RS08810	COG3039	Transposase
ACU11_RS08820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACU11_RS08820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACU11_RS08825	COG1105	Belongs to the carbohydrate kinase PfkB family
ACU11_RS08830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACU11_RS08830	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACU11_RS08835	COG1609	Transcriptional regulator
ACU11_RS08845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU11_RS08850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU11_RS08860	COG2902	Dehydrogenase
ACU11_RS08870	COG0477	Major facilitator Superfamily
ACU11_RS08880	COG5002	protein histidine kinase activity
ACU11_RS08880	COG2205	protein histidine kinase activity
ACU11_RS08880	COG0784	Response regulator, receiver
ACU11_RS08885	COG2733	membrane
ACU11_RS08895	COG1121	(ABC) transporter
ACU11_RS08900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACU11_RS08915	COG0243	molybdopterin cofactor binding
ACU11_RS08920	COG0477	Major facilitator Superfamily
ACU11_RS08930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU11_RS08935	COG0174	glutamine synthetase
ACU11_RS08940	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACU11_RS08990	COG2801	Transposase and inactivated derivatives
ACU11_RS08995	COG2201	protein-glutamate methylesterase activity
ACU11_RS09020	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ACU11_RS09040	COG3842	ATPase activity
ACU11_RS09045	COG1176	ABC-type spermidine putrescine transport system, permease component I
ACU11_RS09050	COG1177	transmembrane transport
ACU11_RS09055	COG1012	belongs to the aldehyde dehydrogenase family
ACU11_RS09070	COG4535	Mg2 and Co2 transporter CorC
ACU11_RS09090	COG1702	phosphate starvation-inducible protein PhoH
ACU11_RS09110	COG0741	lytic transglycosylase activity
ACU11_RS09115	COG0723	plastoquinol--plastocyanin reductase activity
ACU11_RS09120	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ACU11_RS09125	COG2857	Cytochrome c1
ACU11_RS09130	COG0625	glutathione transferase activity
ACU11_RS09135	COG2969	positive regulation of protein catabolic process
ACU11_RS09160	COG0840	transmembrane signaling receptor activity
ACU11_RS09165	COG0835	chemotaxis
ACU11_RS09275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACU11_RS09330	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACU11_RS09345	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACU11_RS09350	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACU11_RS09350	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACU11_RS09355	COG0802	atpase or kinase
ACU11_RS09360	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACU11_RS09365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACU11_RS09385	COG1028	Short-chain dehydrogenase reductase Sdr
ACU11_RS09405	COG2081	HI0933 family
ACU11_RS09410	COG4681	YaeQ
ACU11_RS09415	COG1671	Belongs to the UPF0178 family
ACU11_RS09420	COG1278	Cold shock
ACU11_RS09425	COG0625	glutathione transferase activity
ACU11_RS09435	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ACU11_RS09445	COG0513	Belongs to the DEAD box helicase family
ACU11_RS09450	COG0488	(ABC) transporter
ACU11_RS09470	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACU11_RS09475	COG0483	inositol monophosphate 1-phosphatase activity
ACU11_RS09490	COG5001	Diguanylate cyclase
ACU11_RS09490	COG3300	MHYT domain
ACU11_RS09495	COG1509	lysine 2,3-aminomutase activity
ACU11_RS09510	COG0402	S-adenosylhomocysteine deaminase activity
ACU11_RS09515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACU11_RS09555	COG1741	Belongs to the pirin family
ACU11_RS09560	COG0583	DNA-binding transcription factor activity
ACU11_RS09585	COG0352	thiamine-phosphate diphosphorylase activity
ACU11_RS09585	COG0351	phosphomethylpyrimidine kinase
ACU11_RS09595	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ACU11_RS09600	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACU11_RS09615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACU11_RS09625	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ACU11_RS09630	COG3734	2-keto-3-deoxy-galactonokinase
ACU11_RS09640	COG4948	Mandelate Racemase Muconate Lactonizing
ACU11_RS09645	COG0800	Aldolase
ACU11_RS09670	COG1070	Carbohydrate kinase
ACU11_RS09680	COG0477	Major facilitator Superfamily
ACU11_RS09685	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACU11_RS09690	COG1469	GTP cyclohydrolase I activity
ACU11_RS09700	COG0617	tRNA 3'-terminal CCA addition
ACU11_RS09720	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ACU11_RS09745	COG1472	Belongs to the glycosyl hydrolase 3 family
ACU11_RS09755	COG3706	GGDEF domain
ACU11_RS09755	COG2203	Gaf domain
ACU11_RS09755	COG5001	Diguanylate cyclase
ACU11_RS09755	COG4251	negative regulation of phosphorylation
ACU11_RS09760	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU11_RS09765	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ACU11_RS09780	COG0671	phosphoesterase, PA-phosphatase related
ACU11_RS09790	COG1794	racemase activity, acting on amino acids and derivatives
ACU11_RS09795	COG0697	spore germination
ACU11_RS09800	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACU11_RS09820	COG1012	belongs to the aldehyde dehydrogenase family
ACU11_RS09835	COG0460	homoserine dehydrogenase
ACU11_RS09835	COG0527	aspartate kinase activity
ACU11_RS09845	COG2963	transposase activity
ACU11_RS09885	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACU11_RS09900	COG0124	histidyl-tRNA synthetase
ACU11_RS09910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACU11_RS09925	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACU11_RS09925	COG0131	Imidazoleglycerol-phosphate dehydratase
ACU11_RS09935	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACU11_RS09945	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACU11_RS09945	COG0140	phosphoribosyl-ATP diphosphatase activity
ACU11_RS09970	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ACU11_RS09975	COG0235	Class ii aldolase
ACU11_RS09980	COG0531	amino acid
ACU11_RS09985	COG0531	amino acid
ACU11_RS09995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACU11_RS10000	COG0277	FAD linked oxidase domain protein
ACU11_RS10020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACU11_RS10070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACU11_RS10075	COG2258	MOSC domain
ACU11_RS10080	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACU11_RS10085	COG0505	Belongs to the CarA family
ACU11_RS10095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACU11_RS10100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACU11_RS10110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACU11_RS10125	COG3279	Response regulator of the LytR AlgR family
ACU11_RS10130	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACU11_RS10145	COG2205	protein histidine kinase activity
ACU11_RS10145	COG2198	Histidine kinase
ACU11_RS10145	COG0784	Response regulator, receiver
ACU11_RS10150	COG1024	Enoyl-CoA hydratase
ACU11_RS10155	COG0318	PFAM AMP-dependent synthetase and ligase
ACU11_RS10185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACU11_RS10210	COG0840	transmembrane signaling receptor activity
ACU11_RS10220	COG0835	chemotaxis
ACU11_RS10230	COG0840	transmembrane signaling receptor activity
ACU11_RS10235	COG0840	transmembrane signaling receptor activity
ACU11_RS10240	COG0840	transmembrane signaling receptor activity
ACU11_RS10245	COG0840	transmembrane signaling receptor activity
ACU11_RS10250	COG0840	transmembrane signaling receptor activity
ACU11_RS10255	COG0840	transmembrane signaling receptor activity
ACU11_RS10260	COG0840	transmembrane signaling receptor activity
ACU11_RS10265	COG0840	transmembrane signaling receptor activity
ACU11_RS10275	COG0840	transmembrane signaling receptor activity
ACU11_RS10280	COG0840	transmembrane signaling receptor activity
ACU11_RS10290	COG0840	transmembrane signaling receptor activity
ACU11_RS10300	COG0745	RESPONSE REGULATOR receiver
ACU11_RS10310	COG0835	chemotaxis
ACU11_RS10315	COG1192	Involved in chromosome partitioning
ACU11_RS10320	COG1360	Flagellar Motor Protein
ACU11_RS10325	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACU11_RS10340	COG4774	siderophore transport
ACU11_RS10345	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACU11_RS10425	COG0643	Histidine kinase
ACU11_RS10425	COG2198	Histidine kinase
ACU11_RS10425	COG0784	Response regulator, receiver
ACU11_RS10475	COG3039	Transposase
ACU11_RS10485	COG1684	flagellar biosynthetic protein fliR
ACU11_RS10500	COG3190	flagellar
ACU11_RS10550	COG1677	Flagellar hook-basal body complex protein FliE
ACU11_RS10580	COG1028	Short-chain dehydrogenase reductase Sdr
ACU11_RS10585	COG4221	oxidoreductase activity
ACU11_RS10590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACU11_RS10610	COG2201	protein-glutamate methylesterase activity
ACU11_RS10640	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ACU11_RS10645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACU11_RS10680	COG4787	bacterial-type flagellum-dependent cell motility
ACU11_RS10690	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ACU11_RS10695	COG1558	bacterial-type flagellum-dependent cell motility
ACU11_RS10705	COG0784	Response regulator, receiver
ACU11_RS10705	COG0835	chemotaxis
ACU11_RS10725	COG4191	Histidine kinase
ACU11_RS10735	COG4585	Histidine kinase
ACU11_RS10775	COG0482	sulfurtransferase activity
ACU11_RS10790	COG0542	response to heat
ACU11_RS10820	COG0492	ferredoxin-NADP+ reductase activity
ACU11_RS10825	COG1674	ftsk spoiiie
ACU11_RS10845	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACU11_RS10865	COG0038	chloride channel
ACU11_RS10870	COG0183	Belongs to the thiolase family
ACU11_RS10875	COG1024	Enoyl-CoA hydratase
ACU11_RS10875	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACU11_RS10890	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACU11_RS10910	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU11_RS10915	COG1160	GTP binding
ACU11_RS10920	COG0303	'Molybdopterin
ACU11_RS10930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACU11_RS10955	COG3039	Transposase
ACU11_RS10965	COG3039	Transposase
ACU11_RS10975	COG3039	Transposase
ACU11_RS10995	COG0746	molybdenum cofactor guanylyltransferase activity
ACU11_RS11020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACU11_RS11020	COG1648	precorrin-2 dehydrogenase activity
ACU11_RS11055	COG3039	Transposase
ACU11_RS11065	COG5001	Diguanylate cyclase
ACU11_RS11080	COG4566	intracellular signal transduction
ACU11_RS11120	COG2201	protein-glutamate methylesterase activity
ACU11_RS11125	COG2963	transposase activity
ACU11_RS11145	COG2801	Transposase and inactivated derivatives
ACU11_RS11180	COG3039	Transposase
ACU11_RS11185	COG3039	Transposase
ACU11_RS11190	COG3039	Transposase
ACU11_RS11210	COG3039	Transposase
ACU11_RS11235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU11_RS11240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU11_RS11285	COG3328	transposase activity
ACU11_RS11300	COG1858	cytochrome C peroxidase
ACU11_RS11325	COG0515	serine threonine protein kinase
ACU11_RS11330	COG0631	protein serine/threonine phosphatase activity
ACU11_RS11375	COG3039	Transposase
ACU11_RS11475	COG2963	transposase activity
ACU11_RS11490	COG2154	pterin-4-alpha-carbinolamine dehydratase
ACU11_RS11505	COG3064	Membrane
ACU11_RS11515	COG1530	ribonuclease E activity
ACU11_RS11525	COG1054	Belongs to the UPF0176 family
ACU11_RS11545	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACU11_RS11560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACU11_RS11585	COG0582	viral genome integration into host DNA
ACU11_RS11610	COG0322	excinuclease ABC activity
ACU11_RS11620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACU11_RS11630	COG1663	tetraacyldisaccharide 4'-kinase activity
ACU11_RS11645	COG0811	peptide transport
ACU11_RS11670	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACU11_RS11685	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACU11_RS11700	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ACU11_RS11710	COG0354	folic acid binding
ACU11_RS11720	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACU11_RS11730	COG0363	glucosamine-6-phosphate deaminase activity
ACU11_RS11735	COG0129	dihydroxy-acid dehydratase activity
ACU11_RS11740	COG0800	Aldolase
ACU11_RS11750	COG2826	transposase and inactivated derivatives, IS30 family
ACU11_RS11830	COG3039	Transposase
ACU11_RS11925	COG2205	protein histidine kinase activity
ACU11_RS11925	COG0784	Response regulator, receiver
ACU11_RS11930	COG2183	response to ionizing radiation
ACU11_RS11940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU11_RS11940	COG0723	plastoquinol--plastocyanin reductase activity
ACU11_RS11955	COG3243	poly(R)-hydroxyalkanoic acid synthase
ACU11_RS11965	COG1183	phosphatidylcholine synthase activity
ACU11_RS11970	COG1028	Short-chain dehydrogenase reductase Sdr
ACU11_RS11995	COG0668	transmembrane transport
ACU11_RS12015	COG1914	H( )-stimulated, divalent metal cation uptake system
ACU11_RS12035	COG0583	DNA-binding transcription factor activity
ACU11_RS12040	COG0583	DNA-binding transcription factor activity
ACU11_RS12060	COG0583	DNA-binding transcription factor activity
ACU11_RS12065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACU11_RS12070	COG3002	Belongs to the UPF0753 family
ACU11_RS12075	COG0519	Catalyzes the synthesis of GMP from XMP
ACU11_RS12075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACU11_RS12085	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACU11_RS12100	COG0475	glutathione-regulated potassium exporter activity
ACU11_RS12100	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACU11_RS12105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACU11_RS12115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACU11_RS12120	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ACU11_RS12130	COG0776	regulation of translation
ACU11_RS12135	COG0539	negative regulation of cytoplasmic translation
ACU11_RS12140	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACU11_RS12155	COG2957	Belongs to the agmatine deiminase family
ACU11_RS12160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACU11_RS12185	COG0395	ABC-type sugar transport system, permease component
ACU11_RS12190	COG1175	transmembrane transport
ACU11_RS12220	COG2350	Protein conserved in bacteria
ACU11_RS12225	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACU11_RS12230	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACU11_RS12235	COG1187	pseudouridine synthase activity
ACU11_RS12255	COG0436	Aminotransferase
ACU11_RS12260	COG4133	protoheme IX ABC transporter activity
ACU11_RS12320	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ACU11_RS12325	COG4988	ABC transporter
ACU11_RS12335	COG1271	oxidase subunit
ACU11_RS12340	COG1294	oxidase, subunit
ACU11_RS12385	COG0165	Argininosuccinate lyase
ACU11_RS12400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACU11_RS12405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACU11_RS12415	COG0137	argininosuccinate synthase activity
ACU11_RS12420	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACU11_RS12435	COG2166	iron-sulfur cluster assembly
ACU11_RS12465	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACU11_RS12485	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACU11_RS12495	COG0305	Participates in initiation and elongation during chromosome replication
ACU11_RS12505	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ACU11_RS12510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACU11_RS12515	COG2137	regulation of response to DNA damage stimulus
ACU11_RS12520	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACU11_RS12535	COG1546	Belongs to the CinA family
ACU11_RS12540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACU11_RS12555	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACU11_RS12565	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ACU11_RS12570	COG1534	Rna-binding protein
ACU11_RS12575	COG3737	Protein of unknown function (DUF498/DUF598)
ACU11_RS12585	COG1238	metal cluster binding
ACU11_RS12590	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACU11_RS12595	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACU11_RS12600	COG2840	Smr protein MutS2
ACU11_RS12610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACU11_RS12620	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ACU11_RS12625	COG0148	phosphopyruvate hydratase activity
ACU11_RS12635	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ACU11_RS12640	COG0504	CTP synthase activity
ACU11_RS12675	COG1253	flavin adenine dinucleotide binding
ACU11_RS12690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACU11_RS12695	COG2271	Major facilitator Superfamily
ACU11_RS12700	COG1132	(ABC) transporter
ACU11_RS12705	COG1136	(ABC) transporter
ACU11_RS12720	COG0438	transferase activity, transferring glycosyl groups
ACU11_RS12730	COG2264	protein methyltransferase activity
ACU11_RS12760	COG2244	polysaccharide biosynthetic process
ACU11_RS12810	COG1595	DNA-templated transcription, initiation
ACU11_RS12825	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACU11_RS12845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACU11_RS12870	COG3039	Transposase
ACU11_RS12885	COG0840	transmembrane signaling receptor activity
ACU11_RS12895	COG2801	Transposase and inactivated derivatives
ACU11_RS12915	COG2826	transposase and inactivated derivatives, IS30 family
ACU11_RS12925	COG3039	Transposase
ACU11_RS12960	COG0583	DNA-binding transcription factor activity
ACU11_RS12970	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACU11_RS12985	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACU11_RS12990	COG0077	Prephenate dehydratase
ACU11_RS12990	COG1605	Chorismate mutase
ACU11_RS12995	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ACU11_RS13000	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACU11_RS13040	COG1228	amidohydrolase
ACU11_RS13045	COG2986	histidine ammonia-lyase
ACU11_RS13055	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ACU11_RS13075	COG2963	transposase activity
ACU11_RS13090	COG0556	nucleotide-excision repair
ACU11_RS13095	COG4969	Belongs to the N-Me-Phe pilin family
ACU11_RS13150	COG4695	Portal protein
ACU11_RS13195	COG3179	chitinase
ACU11_RS13390	COG1611	Belongs to the LOG family
ACU11_RS13400	COG2095	MarC family integral membrane protein
ACU11_RS13410	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACU11_RS13445	COG1185	polyribonucleotide nucleotidyltransferase activity
ACU11_RS13450	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACU11_RS13465	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACU11_RS13470	COG0195	Participates in both transcription termination and antitermination
ACU11_RS13475	COG0779	Required for maturation of 30S ribosomal subunits
ACU11_RS13485	COG1007	ATP synthesis coupled electron transport
ACU11_RS13515	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACU11_RS13520	COG1034	ATP synthesis coupled electron transport
ACU11_RS13525	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACU11_RS13530	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ACU11_RS13535	COG0649	NAD binding
ACU11_RS13540	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACU11_RS13550	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACU11_RS13565	COG0149	triose-phosphate isomerase activity
ACU11_RS13600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACU11_RS13605	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ACU11_RS13620	COG0133	tryptophan synthase activity
ACU11_RS13630	COG0135	phosphoribosylanthranilate isomerase activity
ACU11_RS13635	COG0101	tRNA pseudouridine synthase activity
ACU11_RS13650	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACU11_RS13655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACU11_RS13660	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACU11_RS13665	COG2890	protein-(glutamine-N5) methyltransferase activity
ACU11_RS13685	COG0433	COG0433 Predicted ATPase
ACU11_RS13700	COG2801	Transposase and inactivated derivatives
ACU11_RS13715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACU11_RS13725	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACU11_RS13750	COG0717	Belongs to the dCTP deaminase family
ACU11_RS13755	COG0489	protein tyrosine kinase activity
ACU11_RS13760	COG3293	Transposase
ACU11_RS13770	COG3706	GGDEF domain
ACU11_RS13790	COG1028	Short-chain dehydrogenase reductase Sdr
ACU11_RS13795	COG3039	Transposase
ACU11_RS13810	COG0415	Belongs to the DNA photolyase family
ACU11_RS13815	COG0305	Participates in initiation and elongation during chromosome replication
ACU11_RS13825	COG0367	asparagine synthase
ACU11_RS13840	COG1960	acyl-CoA dehydrogenase activity
ACU11_RS13855	COG0084	hydrolase, TatD family'
ACU11_RS13860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACU11_RS13915	COG0386	Belongs to the glutathione peroxidase family
ACU11_RS14010	COG2814	Major facilitator Superfamily
ACU11_RS14015	COG1566	PFAM secretion protein HlyD family protein
ACU11_RS14050	COG4774	siderophore transport
ACU11_RS14065	COG0367	asparagine synthase
ACU11_RS14070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACU11_RS14080	COG1393	Belongs to the ArsC family
ACU11_RS14140	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACU11_RS14155	COG0233	cytoplasmic translational termination
ACU11_RS14165	COG0575	Belongs to the CDS family
ACU11_RS14170	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ACU11_RS14175	COG0750	zinc metalloprotease
ACU11_RS14185	COG3039	Transposase
ACU11_RS14190	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACU11_RS14195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACU11_RS14200	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACU11_RS14220	COG0825	malonyl-CoA metabolic process
ACU11_RS14245	COG1981	membrane
ACU11_RS14265	COG1695	Transcriptional regulator
ACU11_RS14295	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ACU11_RS14305	COG2040	homocysteine
ACU11_RS14310	COG0833	amino acid
ACU11_RS14315	COG0346	lactoylglutathione lyase activity
ACU11_RS14325	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACU11_RS14325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACU11_RS14335	COG2878	Part of a membrane complex involved in electron transport
ACU11_RS14355	COG1595	DNA-templated transcription, initiation
ACU11_RS14380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACU11_RS14395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACU11_RS14400	COG0251	oxidation-reduction process
ACU11_RS14410	COG0392	lysyltransferase activity
ACU11_RS14410	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ACU11_RS14440	COG2814	Major facilitator Superfamily
ACU11_RS14445	COG1902	pentaerythritol trinitrate reductase activity
ACU11_RS14455	COG2824	Alkylphosphonate utilization operon protein PhnA
ACU11_RS14465	COG1047	Peptidyl-prolyl cis-trans
ACU11_RS14500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACU11_RS14515	COG1451	nucleotide metabolic process
ACU11_RS14530	COG0183	Belongs to the thiolase family
ACU11_RS14560	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ACU11_RS14560	COG1793	dna ligase
ACU11_RS14570	COG1793	dna ligase
ACU11_RS14575	COG1201	RNA secondary structure unwinding
ACU11_RS14590	COG1278	Cold shock
ACU11_RS14595	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ACU11_RS14600	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ACU11_RS14610	COG3046	protein related to deoxyribodipyrimidine photolyase
ACU11_RS14615	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
ACU11_RS14620	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACU11_RS14625	COG2954	triphosphatase activity
ACU11_RS14640	COG1381	Involved in DNA repair and RecF pathway recombination
ACU11_RS14660	COG0681	Belongs to the peptidase S26 family
ACU11_RS14665	COG0481	GTPase activity
ACU11_RS14670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACU11_RS14710	COG1960	acyl-CoA dehydrogenase activity
ACU11_RS14735	COG3250	beta-galactosidase activity
ACU11_RS14770	COG0784	Response regulator, receiver
ACU11_RS14770	COG5002	protein histidine kinase activity
ACU11_RS14775	COG2198	Histidine kinase
ACU11_RS14775	COG2205	protein histidine kinase activity
ACU11_RS14775	COG0784	Response regulator, receiver
ACU11_RS14780	COG2353	YceI-like domain
ACU11_RS14810	COG1760	l-serine dehydratase
ACU11_RS14820	COG0626	cystathionine gamma-synthase activity
ACU11_RS14825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACU11_RS14830	COG0739	heme binding
ACU11_RS14840	COG1272	protein, Hemolysin III
ACU11_RS14850	COG0516	GMP reductase activity
ACU11_RS14850	COG0517	IMP dehydrogenase activity
ACU11_RS14855	COG0463	Glycosyl transferase, family 2
ACU11_RS14865	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ACU11_RS14875	COG4771	TonB-dependent receptor
ACU11_RS14880	COG1309	transcriptional regulator
ACU11_RS14890	COG1960	acyl-CoA dehydrogenase activity
ACU11_RS14915	COG0509	glycine decarboxylation via glycine cleavage system
ACU11_RS14930	COG0330	HflC and HflK could
ACU11_RS14935	COG1742	UPF0060 membrane protein
ACU11_RS14940	COG3956	TIGRFAM MazG family protein
ACU11_RS14950	COG0494	nUDIX hydrolase
ACU11_RS14960	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACU11_RS14965	COG0837	glucose binding
ACU11_RS14980	COG1388	LysM domain
ACU11_RS14980	COG3858	chitin binding
ACU11_RS14985	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ACU11_RS14995	COG1472	Belongs to the glycosyl hydrolase 3 family
ACU11_RS15020	COG3537	Alpha-1,2-mannosidase
ACU11_RS15060	COG3142	Participates in the control of copper homeostasis
ACU11_RS15065	COG1446	asparaginase
ACU11_RS15155	COG0643	Histidine kinase
ACU11_RS15155	COG0784	Response regulator, receiver
ACU11_RS15155	COG2198	Histidine kinase
ACU11_RS15160	COG0840	transmembrane signaling receptor activity
ACU11_RS15165	COG0835	chemotaxis
ACU11_RS15180	COG0189	ligase activity
ACU11_RS15190	COG1397	ADP-ribosylglycohydrolase
ACU11_RS15200	COG1199	ATP-dependent helicase activity
ACU11_RS15210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACU11_RS15215	COG1215	transferase activity, transferring glycosyl groups
ACU11_RS15225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACU11_RS15280	COG1643	Atp-dependent helicase
ACU11_RS15285	COG0783	Belongs to the Dps family
ACU11_RS15290	COG0514	ATP-dependent DNA helicase (RecQ)
ACU11_RS15305	COG1187	pseudouridine synthase activity
ACU11_RS15315	COG0840	transmembrane signaling receptor activity
ACU11_RS15340	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACU11_RS15505	COG3179	chitinase
ACU11_RS15550	COG4695	Portal protein
ACU11_RS15615	COG0602	queuosine metabolic process
ACU11_RS15625	COG2885	chlorophyll binding
ACU11_RS15630	COG0823	Involved in the tonB-independent uptake of proteins
ACU11_RS15650	COG0824	Thioesterase
ACU11_RS15655	COG2255	four-way junction helicase activity
ACU11_RS15690	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACU11_RS15705	COG0477	Major facilitator Superfamily
ACU11_RS15720	COG2755	lipolytic protein G-D-S-L family
ACU11_RS15720	COG0657	acetylesterase activity
ACU11_RS15740	COG0488	(ABC) transporter
ACU11_RS15770	COG4651	solute:proton antiporter activity
ACU11_RS15770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACU11_RS15775	COG2801	Transposase and inactivated derivatives
ACU11_RS15785	COG4772	TonB-dependent receptor
ACU11_RS15795	COG4264	IucA IucC family
ACU11_RS15800	COG2814	Major facilitator Superfamily
ACU11_RS15810	COG0019	diaminopimelate decarboxylase activity
ACU11_RS15855	COG4206	TonB-dependent receptor
ACU11_RS15865	COG2963	transposase activity
ACU11_RS15870	COG0542	response to heat
ACU11_RS15895	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ACU11_RS15905	COG2826	transposase and inactivated derivatives, IS30 family
ACU11_RS15910	COG0534	Mate efflux family protein
ACU11_RS15920	COG0336	Belongs to the RNA methyltransferase TrmD family
ACU11_RS15925	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACU11_RS15930	COG0228	four-way junction DNA binding
ACU11_RS15955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACU11_RS15965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACU11_RS16005	COG2172	sigma factor antagonist activity
ACU11_RS16010	COG1366	Belongs to the anti-sigma-factor antagonist family
ACU11_RS16015	COG1366	Belongs to the anti-sigma-factor antagonist family
ACU11_RS16025	COG0326	Molecular chaperone. Has ATPase activity
ACU11_RS16030	COG2207	Transcriptional regulator
ACU11_RS16055	COG2963	transposase activity
ACU11_RS16095	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ACU11_RS16100	COG1845	cytochrome c oxidase, subunit III
ACU11_RS16105	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACU11_RS16120	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACU11_RS16125	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACU11_RS16135	COG0196	riboflavin kinase activity
ACU11_RS16140	COG0728	peptidoglycan biosynthetic process
ACU11_RS16145	COG0268	Binds directly to 16S ribosomal RNA
ACU11_RS16150	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACU11_RS16155	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ACU11_RS16165	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACU11_RS16170	COG0824	Thioesterase
ACU11_RS16185	COG1946	Acyl-CoA thioesterase
ACU11_RS16195	COG1595	DNA-templated transcription, initiation
ACU11_RS16210	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ACU11_RS16225	COG3293	Transposase
ACU11_RS16255	COG1877	trehalose-phosphatase activity
ACU11_RS16260	COG3387	PFAM Glycoside hydrolase 15-related
ACU11_RS16275	COG0840	transmembrane signaling receptor activity
ACU11_RS16280	COG3011	Protein conserved in bacteria
ACU11_RS16295	COG0564	pseudouridine synthase activity
ACU11_RS16300	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU11_RS16305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACU11_RS16305	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACU11_RS16315	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ACU11_RS16320	COG0045	succinate-CoA ligase (ADP-forming) activity
ACU11_RS16335	COG2184	nucleotidyltransferase activity
ACU11_RS16355	COG2194	sulfuric ester hydrolase activity
ACU11_RS16360	COG4969	Belongs to the N-Me-Phe pilin family
ACU11_RS16370	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ACU11_RS16380	COG3039	Transposase
ACU11_RS16385	COG3209	COG3209 Rhs family protein
ACU11_RS16415	COG0745	RESPONSE REGULATOR receiver
ACU11_RS16455	COG3039	Transposase
ACU11_RS16510	COG2022	thiamine diphosphate biosynthetic process
ACU11_RS16520	COG3273	potassium ion transport
ACU11_RS16520	COG0471	metal ion transport
ACU11_RS16540	COG1970	mechanosensitive ion channel activity
ACU11_RS16545	COG3328	transposase activity
ACU11_RS16550	COG2801	Transposase and inactivated derivatives
ACU11_RS16555	COG2963	transposase activity
ACU11_RS16565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACU11_RS16585	COG0308	aminopeptidase N
ACU11_RS16590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU11_RS16600	COG0529	Catalyzes the synthesis of activated sulfate
ACU11_RS16600	COG2895	sulfate adenylyltransferase (ATP) activity
ACU11_RS16605	COG0175	sulfate reduction
ACU11_RS16610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACU11_RS16615	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACU11_RS16620	COG0175	sulfate reduction
ACU11_RS16640	COG0784	Response regulator, receiver
ACU11_RS16640	COG2198	Histidine kinase
ACU11_RS16640	COG2205	protein histidine kinase activity
ACU11_RS16670	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ACU11_RS16675	COG3588	fructose-bisphosphate aldolase
ACU11_RS16680	COG0469	pyruvate kinase activity
ACU11_RS16690	COG0126	phosphoglycerate kinase activity
ACU11_RS16700	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACU11_RS16715	COG3453	Protein conserved in bacteria
ACU11_RS16715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACU11_RS16720	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACU11_RS16725	COG4149	molybdate abc transporter
ACU11_RS16730	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ACU11_RS16775	COG1022	Amp-dependent synthetase and ligase
ACU11_RS16815	COG1376	ErfK ybiS ycfS ynhG family protein
ACU11_RS16825	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACU11_RS16830	COG1301	dicarboxylic acid transport
ACU11_RS16835	COG2963	transposase activity
ACU11_RS16860	COG2304	oxidoreductase activity
ACU11_RS16880	COG0714	Associated with various cellular activities
ACU11_RS16910	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACU11_RS16935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACU11_RS16945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACU11_RS16960	COG1561	YicC-like family, N-terminal region
ACU11_RS16965	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ACU11_RS16970	COG0346	lactoylglutathione lyase activity
ACU11_RS16980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACU11_RS17005	COG0006	proline dipeptidase activity
ACU11_RS17025	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACU11_RS17045	COG2912	Transglutaminase-like superfamily
ACU11_RS17050	COG1773	rubredoxin
ACU11_RS17055	COG0352	thiamine-phosphate diphosphorylase activity
ACU11_RS17065	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACU11_RS17090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACU11_RS17125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACU11_RS17130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACU11_RS17150	COG1028	Short-chain dehydrogenase reductase Sdr
ACU11_RS17165	COG3781	membrane
ACU11_RS17175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACU11_RS17210	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ACU11_RS17220	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACU11_RS17240	COG3710	Transcriptional regulator
ACU11_RS17245	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACU11_RS17250	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACU11_RS17280	COG2226	methyltransferase
ACU11_RS17285	COG0066	3-isopropylmalate dehydratase activity
ACU11_RS17290	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACU11_RS17310	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACU11_RS17315	COG1538	Outer membrane efflux protein
ACU11_RS17320	COG1519	Transferase
ACU11_RS17325	COG1560	Kdo2-lipid A biosynthetic process
ACU11_RS17355	COG0281	malic enzyme
ACU11_RS17355	COG0280	phosphate acetyltransferase
ACU11_RS17370	COG4191	Histidine kinase
ACU11_RS17385	COG0583	DNA-binding transcription factor activity
ACU11_RS17410	COG2197	response regulator
ACU11_RS17420	COG0642	Histidine kinase
ACU11_RS17435	COG2851	Citrate transporter
ACU11_RS17440	COG1028	Short-chain dehydrogenase reductase Sdr
ACU11_RS17445	COG1609	Transcriptional regulator
ACU11_RS17455	COG2211	Major facilitator Superfamily
ACU11_RS17485	COG0436	Aminotransferase
ACU11_RS17500	COG0726	polysaccharide deacetylase
ACU11_RS17505	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACU11_RS17525	COG3964	amidohydrolase
ACU11_RS17530	COG0402	S-adenosylhomocysteine deaminase activity
ACU11_RS17550	COG0242	peptide deformylase activity
ACU11_RS17575	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ACU11_RS17620	COG2188	Transcriptional regulator
ACU11_RS17635	COG1450	Type ii and iii secretion system protein
ACU11_RS17650	COG3166	PFAM Fimbrial assembly family protein
ACU11_RS17655	COG3156	type II secretion system protein K
ACU11_RS17660	COG4795	General secretion pathway protein
ACU11_RS17665	COG2165	general secretion pathway protein
ACU11_RS17670	COG4970	Tfp pilus assembly protein FimT
ACU11_RS17675	COG2165	general secretion pathway protein
ACU11_RS17680	COG1459	type II secretion system
ACU11_RS17685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACU11_RS17690	COG1404	Belongs to the peptidase S8 family
ACU11_RS17695	COG5295	Hep Hag repeat protein
ACU11_RS17700	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACU11_RS17700	COG0047	phosphoribosylformylglycinamidine synthase activity
ACU11_RS17705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACU11_RS17710	COG4974	Belongs to the 'phage' integrase family
ACU11_RS17725	COG0795	lipopolysaccharide-transporting ATPase activity
ACU11_RS17735	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACU11_RS17750	COG0525	valine-tRNA ligase activity
ACU11_RS17775	COG1183	phosphatidylcholine synthase activity
ACU11_RS17785	COG0442	prolyl-tRNA aminoacylation
ACU11_RS17800	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACU11_RS17805	COG1127	ABC transporter
ACU11_RS17810	COG3218	ABC-type transport auxiliary lipoprotein component
ACU11_RS17810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACU11_RS17845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACU11_RS17850	COG0662	Cupin 2, conserved barrel domain protein
ACU11_RS17850	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ACU11_RS17875	COG2086	electron transfer activity
ACU11_RS17890	COG0546	phosphoglycolate phosphatase activity
ACU11_RS17890	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACU11_RS17895	COG0277	FAD linked oxidase domain protein
ACU11_RS17910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACU11_RS17965	COG3754	Rhamnan synthesis protein F
ACU11_RS17970	COG1216	Glycosyl transferase, family 2
ACU11_RS17970	COG0438	transferase activity, transferring glycosyl groups
ACU11_RS17975	COG0110	maltose O-acetyltransferase activity
ACU11_RS17990	COG0626	cystathionine gamma-synthase activity
ACU11_RS18020	COG0625	glutathione transferase activity
ACU11_RS18030	COG0513	Belongs to the DEAD box helicase family
ACU11_RS18035	COG0720	synthase
ACU11_RS18045	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACU11_RS18050	COG1956	GAF domain-containing protein
ACU11_RS18060	COG0546	phosphoglycolate phosphatase activity
ACU11_RS18085	COG0339	signal peptide processing
ACU11_RS18130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACU11_RS18135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU11_RS18140	COG1136	(ABC) transporter
ACU11_RS18150	COG0577	efflux transmembrane transporter activity
ACU11_RS18150	COG1136	(ABC) transporter
ACU11_RS18155	COG0577	efflux transmembrane transporter activity
ACU11_RS18155	COG1136	(ABC) transporter
ACU11_RS18160	COG1136	(ABC) transporter
ACU11_RS18160	COG0577	efflux transmembrane transporter activity
ACU11_RS18170	COG4191	Histidine kinase
ACU11_RS18195	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACU11_RS18200	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACU11_RS18205	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACU11_RS18215	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACU11_RS18225	COG0356	it plays a direct role in the translocation of protons across the membrane
ACU11_RS18245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACU11_RS18255	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACU11_RS18290	COG2011	ABC-type metal ion transport system permease component
ACU11_RS18300	COG0697	spore germination
ACU11_RS18335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACU11_RS18340	COG1187	pseudouridine synthase activity
ACU11_RS18345	COG2813	Specifically methylates the guanine in position
ACU11_RS18370	COG2205	protein histidine kinase activity
ACU11_RS18370	COG2202	Pas domain
ACU11_RS18395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU11_RS18440	COG0745	RESPONSE REGULATOR receiver
ACU11_RS18455	COG1404	Belongs to the peptidase S8 family
ACU11_RS18470	COG0842	Transport permease protein
ACU11_RS18475	COG1131	(ABC) transporter
ACU11_RS18480	COG0025	NhaP-type Na H and K H
ACU11_RS18485	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ACU11_RS18490	COG1573	uracil-dna glycosylase
ACU11_RS18500	COG3384	dioxygenase
ACU11_RS18515	COG0667	Aldo Keto reductase
ACU11_RS18530	COG3590	peptidase
ACU11_RS18545	COG3039	Transposase
ACU11_RS18550	COG0531	amino acid
ACU11_RS18565	COG2972	Histidine kinase
ACU11_RS18605	COG1271	oxidase subunit
ACU11_RS18610	COG1294	oxidase, subunit
ACU11_RS18625	COG1063	alcohol dehydrogenase
ACU11_RS18705	COG2963	transposase activity
ACU11_RS18725	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ACU11_RS18760	COG2353	YceI-like domain
ACU11_RS18765	COG2801	Transposase and inactivated derivatives
ACU11_RS18815	COG3039	Transposase
ACU11_RS18870	COG3210	domain, Protein
ACU11_RS18890	COG3210	domain, Protein
ACU11_RS18900	COG3210	domain, Protein
ACU11_RS18905	COG2831	hemolysin activation secretion protein
ACU11_RS18925	COG2963	transposase activity
ACU11_RS18930	COG3209	COG3209 Rhs family protein
ACU11_RS18935	COG3039	Transposase
ACU11_RS18945	COG2826	transposase and inactivated derivatives, IS30 family
ACU11_RS18955	COG2951	lytic endotransglycosylase activity
ACU11_RS18960	COG2963	transposase activity
ACU11_RS18980	COG3039	Transposase
ACU11_RS18995	COG0577	efflux transmembrane transporter activity
ACU11_RS19035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACU11_RS19045	COG0842	Transport permease protein
ACU11_RS19050	COG1131	(ABC) transporter
ACU11_RS19055	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACU11_RS19075	COG1476	TRANSCRIPTIONal
ACU11_RS19085	COG4555	ABC transporter
ACU11_RS19120	COG0625	glutathione transferase activity
ACU11_RS19155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACU11_RS19165	COG1560	Kdo2-lipid A biosynthetic process
ACU11_RS19210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACU11_RS19210	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACU11_RS19215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACU11_RS19220	COG0242	peptide deformylase activity
ACU11_RS19225	COG1652	LysM domain
ACU11_RS19230	COG0758	DNA mediated transformation
ACU11_RS19250	COG1754	DNA topoisomerase type I activity
ACU11_RS19250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACU11_RS19255	COG0009	L-threonylcarbamoyladenylate synthase
ACU11_RS19270	COG1028	Short-chain dehydrogenase reductase Sdr
ACU11_RS19280	COG0616	signal peptide processing
ACU11_RS19285	COG0534	Mate efflux family protein
ACU11_RS19305	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACU11_RS19310	COG1324	tolerance protein
ACU11_RS19325	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ACU11_RS19330	COG0511	ligase activity, forming carbon-carbon bonds
ACU11_RS19340	COG0439	Biotin carboxylase
ACU11_RS19380	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ACU11_RS19395	COG0138	bifunctional purine biosynthesis protein purh
ACU11_RS19400	COG0151	Belongs to the GarS family
ACU11_RS19405	COG1136	(ABC) transporter
ACU11_RS19405	COG0577	efflux transmembrane transporter activity
ACU11_RS19415	COG1289	transmembrane transporter activity
ACU11_RS19430	COG2814	Major facilitator Superfamily
ACU11_RS19445	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ACU11_RS19515	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACU11_RS19525	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ACU11_RS19535	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ACU11_RS19540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACU11_RS19550	COG0134	indole-3-glycerol-phosphate synthase activity
ACU11_RS19555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACU11_RS19595	COG0456	acetyltransferase
ACU11_RS19605	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ACU11_RS19630	COG1192	Involved in chromosome partitioning
ACU11_RS19635	COG1475	DNA binding
ACU11_RS19650	COG0463	Glycosyl transferase, family 2
ACU11_RS19675	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACU11_RS19700	COG4221	oxidoreductase activity
ACU11_RS19705	COG2755	lipolytic protein G-D-S-L family
ACU11_RS19705	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACU11_RS19720	COG1166	arginine decarboxylase activity
ACU11_RS19725	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ACU11_RS19750	COG2963	transposase activity
ACU11_RS19810	COG0606	chelatase, subunit chli
ACU11_RS19820	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ACU11_RS19865	COG1090	epimerase
ACU11_RS19870	COG0642	Histidine kinase
ACU11_RS19880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACU11_RS19910	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACU11_RS19920	COG1595	DNA-templated transcription, initiation
ACU11_RS19925	COG0753	catalase activity
ACU11_RS19965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACU11_RS19970	COG0180	Tryptophanyl-tRNA synthetase
ACU11_RS19975	COG3237	CsbD-like
ACU11_RS20010	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACU11_RS20015	COG3039	Transposase
ACU11_RS20030	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ACU11_RS20045	COG3228	Belongs to the MtfA family
ACU11_RS20075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACU11_RS20110	COG1199	ATP-dependent helicase activity
ACU11_RS20180	COG0702	epimerase
ACU11_RS20185	COG1733	regulation of RNA biosynthetic process
ACU11_RS20210	COG0583	DNA-binding transcription factor activity
ACU11_RS20215	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACU11_RS20225	COG2205	protein histidine kinase activity
ACU11_RS20230	COG2205	protein histidine kinase activity
ACU11_RS20235	COG0745	RESPONSE REGULATOR receiver
ACU11_RS20255	COG1902	pentaerythritol trinitrate reductase activity
ACU11_RS20260	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACU11_RS20270	COG2814	Major facilitator Superfamily
ACU11_RS20275	COG0583	DNA-binding transcription factor activity
ACU11_RS20285	COG0084	hydrolase, TatD family'
ACU11_RS20305	COG2826	transposase and inactivated derivatives, IS30 family
ACU11_RS20330	COG2963	transposase activity
ACU11_RS20375	COG2801	Transposase and inactivated derivatives
ACU11_RS20415	COG3039	Transposase
ACU11_RS20420	COG2826	transposase and inactivated derivatives, IS30 family
ACU11_RS20430	COG0702	epimerase
ACU11_RS20455	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACU11_RS20475	COG1649	PFAM Uncharacterised BCR, COG1649
ACU11_RS20480	COG2354	Protein conserved in bacteria
ACU11_RS20485	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACU11_RS20500	COG1511	domain protein
ACU11_RS20500	COG3264	Mechanosensitive ion channel
ACU11_RS20570	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACU11_RS20675	COG0246	Mannitol dehydrogenase
ACU11_RS20680	COG1472	Belongs to the glycosyl hydrolase 3 family
ACU11_RS20690	COG4948	Mandelate Racemase Muconate Lactonizing
ACU11_RS20700	COG3661	Belongs to the glycosyl hydrolase 67 family
ACU11_RS20720	COG2974	May be involved in recombination
ACU11_RS20740	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACU11_RS20750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACU11_RS20755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACU11_RS20760	COG0805	protein transport
ACU11_RS20770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACU11_RS20770	COG0519	Catalyzes the synthesis of GMP from XMP
ACU11_RS20780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACU11_RS20785	COG0752	glycyl-tRNA synthetase alpha subunit
ACU11_RS20795	COG0457	Tetratricopeptide repeat
ACU11_RS20810	COG4771	TonB-dependent receptor
ACU11_RS20815	COG0729	surface antigen
ACU11_RS20820	COG2911	Protein conserved in bacteria
ACU11_RS20850	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACU11_RS20855	COG1040	competence protein
ACU11_RS20860	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACU11_RS20865	COG0156	8-amino-7-oxononanoate synthase activity
ACU11_RS20880	COG1028	Short-chain dehydrogenase reductase Sdr
ACU11_RS20905	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACU11_RS20945	COG2963	transposase activity
ACU11_RS20980	COG0657	acetylesterase activity
ACU11_RS20990	COG1414	Transcriptional regulator
ACU11_RS21000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACU11_RS21005	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACU11_RS21015	COG3485	protocatechuate 3,4-dioxygenase
ACU11_RS21020	COG3485	protocatechuate 3,4-dioxygenase
ACU11_RS21030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACU11_RS21035	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACU11_RS21105	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ACU11_RS21115	COG0129	dihydroxy-acid dehydratase activity
ACU11_RS21120	COG2826	transposase and inactivated derivatives, IS30 family
ACU11_RS21150	COG2211	Major facilitator Superfamily
ACU11_RS21170	COG3693	PFAM glycoside hydrolase, family 10
ACU11_RS21175	COG3693	PFAM glycoside hydrolase, family 10
ACU11_RS21210	COG4770	biotin carboxylase activity
ACU11_RS21215	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACU11_RS21220	COG1960	acyl-CoA dehydrogenase activity
ACU11_RS21265	COG0523	cobalamin synthesis protein
ACU11_RS21280	COG0697	spore germination
ACU11_RS21290	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ACU11_RS21295	COG1846	Transcriptional regulator
ACU11_RS21300	COG1764	response to oxidative stress
ACU11_RS21320	COG3293	Transposase
ACU11_RS21335	COG0656	L-ascorbic acid biosynthetic process
ACU11_RS21340	COG2130	NADP-dependent
ACU11_RS21345	COG0667	Aldo Keto reductase
ACU11_RS21355	COG1187	pseudouridine synthase activity
ACU11_RS21365	COG1643	Atp-dependent helicase
ACU11_RS21375	COG4807	Protein conserved in bacteria
ACU11_RS21380	COG2351	hydroxyisourate hydrolase activity
ACU11_RS21405	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACU11_RS21435	COG0604	alcohol dehydrogenase
ACU11_RS21435	COG1028	Short-chain dehydrogenase reductase Sdr
ACU11_RS21435	COG3321	synthase
ACU11_RS21440	COG2937	Belongs to the GPAT DAPAT family
ACU11_RS21470	COG0284	orotidine-5'-phosphate decarboxylase activity
ACU11_RS21475	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ACU11_RS21490	COG0210	DNA helicase
ACU11_RS21505	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ACU11_RS21525	COG3039	Transposase
ACU11_RS21540	COG0564	pseudouridine synthase activity
ACU11_RS21565	COG3706	GGDEF domain
ACU11_RS21575	COG1929	Belongs to the glycerate kinase type-1 family
ACU11_RS21580	COG2271	Major facilitator Superfamily
ACU11_RS21595	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACU11_RS21600	COG0861	Integral membrane protein TerC family
ACU11_RS21610	COG0584	glycerophosphoryl diester phosphodiesterase
ACU11_RS21620	COG0671	phosphoesterase, PA-phosphatase related
ACU11_RS21625	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACU11_RS21630	COG0726	polysaccharide deacetylase
ACU11_RS21670	COG0592	DNA-directed DNA polymerase activity
ACU11_RS21745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU11_RS21900	COG0732	type I restriction modification DNA specificity domain
ACU11_RS21905	COG2801	Transposase and inactivated derivatives
ACU11_RS21920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity