locus-tag	class	description
ACU16_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACU16_RS00020	COG0187	DNA topoisomerase II activity
ACU16_RS00030	COG0501	Belongs to the peptidase M48B family
ACU16_RS00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACU16_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU16_RS00090	COG1064	alcohol dehydrogenase
ACU16_RS00095	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU16_RS00100	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU16_RS00105	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU16_RS00120	COG2234	aminopeptidase activity
ACU16_RS00130	COG4942	peptidase
ACU16_RS00135	COG0793	Belongs to the peptidase S41A family
ACU16_RS00185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACU16_RS00220	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ACU16_RS00235	COG0210	DNA helicase
ACU16_RS00255	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ACU16_RS00260	COG0284	orotidine-5'-phosphate decarboxylase activity
ACU16_RS00290	COG2937	Belongs to the GPAT DAPAT family
ACU16_RS00330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACU16_RS00350	COG2351	hydroxyisourate hydrolase activity
ACU16_RS00420	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACU16_RS00425	COG1074	ATP-dependent DNA helicase activity
ACU16_RS00430	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ACU16_RS00450	COG2801	Transposase and inactivated derivatives
ACU16_RS00455	COG2963	transposase activity
ACU16_RS00460	COG1136	(ABC) transporter
ACU16_RS00475	COG1127	ABC transporter
ACU16_RS00480	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACU16_RS00485	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACU16_RS00500	COG2853	Lipoprotein
ACU16_RS00505	COG0386	Belongs to the glutathione peroxidase family
ACU16_RS00515	COG1322	Protein conserved in bacteria
ACU16_RS00525	COG0531	amino acid
ACU16_RS00540	COG0493	'glutamate synthase
ACU16_RS00545	COG0069	glutamate synthase activity
ACU16_RS00545	COG0070	glutamate synthase
ACU16_RS00545	COG0067	glutamate synthase
ACU16_RS00600	COG1205	dead DEAH box helicase
ACU16_RS00600	COG1111	helicase
ACU16_RS00605	COG1272	protein, Hemolysin III
ACU16_RS00735	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ACU16_RS00745	COG4772	TonB-dependent receptor
ACU16_RS00760	COG3039	Transposase
ACU16_RS00765	COG1304	FMN binding
ACU16_RS00770	COG1755	Isoprenylcysteine carboxyl methyltransferase
ACU16_RS00800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU16_RS00805	COG2801	Transposase and inactivated derivatives
ACU16_RS00810	COG2963	transposase activity
ACU16_RS00815	COG3039	Transposase
ACU16_RS00885	COG3237	CsbD-like
ACU16_RS00930	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS00940	COG0477	Major facilitator Superfamily
ACU16_RS00960	COG0302	gtp cyclohydrolase
ACU16_RS01010	COG0676	glucose-6-phosphate 1-epimerase activity
ACU16_RS01030	COG3135	benzoate transporter
ACU16_RS01060	COG2801	Transposase and inactivated derivatives
ACU16_RS01065	COG2963	transposase activity
ACU16_RS01100	COG2963	transposase activity
ACU16_RS01105	COG2801	Transposase and inactivated derivatives
ACU16_RS01115	COG0366	Alpha amylase catalytic
ACU16_RS01120	COG0366	Alpha amylase catalytic
ACU16_RS01150	COG2755	lipolytic protein G-D-S-L family
ACU16_RS01160	COG3186	Phenylalanine-4-hydroxylase
ACU16_RS01165	COG1522	sequence-specific DNA binding
ACU16_RS01175	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACU16_RS01180	COG1473	amidohydrolase
ACU16_RS01190	COG1119	ATPase activity
ACU16_RS01205	COG0517	IMP dehydrogenase activity
ACU16_RS01205	COG1125	glycine betaine transport
ACU16_RS01220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACU16_RS01225	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ACU16_RS01230	COG3550	peptidyl-serine autophosphorylation
ACU16_RS01235	COG1396	sequence-specific DNA binding
ACU16_RS01255	COG0489	protein tyrosine kinase activity
ACU16_RS01260	COG2062	phosphohistidine phosphatase, SixA
ACU16_RS01270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU16_RS01320	COG1968	undecaprenyl-diphosphatase activity
ACU16_RS01325	COG0174	glutamine synthetase
ACU16_RS01330	COG0347	Belongs to the P(II) protein family
ACU16_RS01335	COG0004	ammonium transporteR
ACU16_RS01340	COG3852	Histidine kinase
ACU16_RS01345	COG2204	response regulator
ACU16_RS01350	COG2032	superoxide dismutase activity
ACU16_RS01355	COG2032	superoxide dismutase activity
ACU16_RS01375	COG2963	transposase activity
ACU16_RS01380	COG2801	Transposase and inactivated derivatives
ACU16_RS01390	COG3039	Transposase
ACU16_RS01400	COG3039	Transposase
ACU16_RS01405	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS01410	COG3039	Transposase
ACU16_RS01435	COG0183	Belongs to the thiolase family
ACU16_RS01475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACU16_RS01480	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ACU16_RS01495	COG0028	Belongs to the TPP enzyme family
ACU16_RS01500	COG4191	Histidine kinase
ACU16_RS01525	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACU16_RS01540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACU16_RS01545	COG3177	Filamentation induced by cAMP protein fic
ACU16_RS01560	COG0596	Alpha beta hydrolase
ACU16_RS01565	COG0727	PFAM Uncharacterised protein family (UPF0153)
ACU16_RS01570	COG0318	PFAM AMP-dependent synthetase and ligase
ACU16_RS01575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACU16_RS01595	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACU16_RS01610	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACU16_RS01625	COG0564	pseudouridine synthase activity
ACU16_RS01645	COG0339	signal peptide processing
ACU16_RS01665	COG3039	Transposase
ACU16_RS01670	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU16_RS01675	COG3265	gluconokinase activity
ACU16_RS01680	COG2211	Major facilitator Superfamily
ACU16_RS01685	COG3459	Glycosyltransferase 36 associated
ACU16_RS01700	COG2205	protein histidine kinase activity
ACU16_RS01710	COG1414	Transcriptional regulator
ACU16_RS01715	COG0738	Major facilitator superfamily
ACU16_RS01745	COG3162	membrane
ACU16_RS01750	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACU16_RS01765	COG0708	Exodeoxyribonuclease III
ACU16_RS01780	COG2091	lysine biosynthetic process via aminoadipic acid
ACU16_RS01790	COG3540	Alkaline phosphatase
ACU16_RS01795	COG0357	Ribosomal RNA small subunit methyltransferase G
ACU16_RS01820	COG2159	amidohydrolase
ACU16_RS01835	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACU16_RS01840	COG0583	DNA-binding transcription factor activity
ACU16_RS01845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU16_RS01860	COG0210	DNA helicase
ACU16_RS01925	COG0408	coproporphyrinogen oxidase activity
ACU16_RS01965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACU16_RS01980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACU16_RS02020	COG1028	Short-chain dehydrogenase reductase Sdr
ACU16_RS02040	COG0463	Glycosyl transferase, family 2
ACU16_RS02050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACU16_RS02055	COG3100	YcgL domain-containing protein
ACU16_RS02070	COG3387	PFAM Glycoside hydrolase 15-related
ACU16_RS02075	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACU16_RS02090	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS02110	COG2239	Acts as a magnesium transporter
ACU16_RS02120	COG0045	succinate-CoA ligase (ADP-forming) activity
ACU16_RS02120	COG1042	CoA-binding domain protein
ACU16_RS02120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACU16_RS02130	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACU16_RS02135	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACU16_RS02160	COG2963	transposase activity
ACU16_RS02165	COG2201	protein-glutamate methylesterase activity
ACU16_RS02170	COG2963	transposase activity
ACU16_RS02225	COG0513	Belongs to the DEAD box helicase family
ACU16_RS02235	COG3039	Transposase
ACU16_RS02240	COG2801	Transposase and inactivated derivatives
ACU16_RS02245	COG2963	transposase activity
ACU16_RS02260	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACU16_RS02275	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACU16_RS02285	COG3483	tryptophan 2,3-dioxygenase activity
ACU16_RS02290	COG3104	oligopeptide transport
ACU16_RS02320	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ACU16_RS02325	COG3039	Transposase
ACU16_RS02330	COG1320	monovalent cation:proton antiporter activity
ACU16_RS02335	COG2212	antiporter activity
ACU16_RS02345	COG0651	ATP synthesis coupled electron transport
ACU16_RS02350	COG1006	Multisubunit Na H antiporter MnhC subunit
ACU16_RS02355	COG2111	Na H antiporter
ACU16_RS02355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACU16_RS02385	COG0708	Exodeoxyribonuclease III
ACU16_RS02390	COG2211	Major facilitator Superfamily
ACU16_RS02405	COG0739	heme binding
ACU16_RS02445	COG2963	transposase activity
ACU16_RS02450	COG2801	Transposase and inactivated derivatives
ACU16_RS02470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACU16_RS02485	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ACU16_RS02535	COG0358	DNA primase activity
ACU16_RS02540	COG1295	ribonuclease BN
ACU16_RS02545	COG1610	YqeY-like protein
ACU16_RS02555	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACU16_RS02560	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACU16_RS02575	COG2133	pyrroloquinoline quinone binding
ACU16_RS02580	COG2801	Transposase and inactivated derivatives
ACU16_RS02585	COG2963	transposase activity
ACU16_RS02590	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS02605	COG4682	membrane
ACU16_RS02625	COG0531	amino acid
ACU16_RS02640	COG4948	Mandelate Racemase Muconate Lactonizing
ACU16_RS02650	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACU16_RS02655	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ACU16_RS02695	COG5383	Protein conserved in bacteria
ACU16_RS02725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU16_RS02730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU16_RS02735	COG1473	amidohydrolase
ACU16_RS02745	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACU16_RS02745	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACU16_RS02775	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACU16_RS02780	COG3118	belongs to the thioredoxin family
ACU16_RS02790	COG2884	Cell division ATP-binding protein ftsE
ACU16_RS02795	COG2177	Part of the ABC transporter FtsEX involved in
ACU16_RS02800	COG2201	protein-glutamate methylesterase activity
ACU16_RS02805	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACU16_RS02810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACU16_RS02815	COG2860	membrane
ACU16_RS02820	COG1252	NADH dehydrogenase
ACU16_RS02850	COG0459	protein refolding
ACU16_RS02875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACU16_RS02890	COG3386	PFAM SMP-30 Gluconolaconase
ACU16_RS02915	COG4221	oxidoreductase activity
ACU16_RS02960	COG0697	spore germination
ACU16_RS02965	COG4305	rare lipoprotein A
ACU16_RS02990	COG1113	amino acid transport
ACU16_RS03000	COG0598	Magnesium transport protein CorA
ACU16_RS03080	COG0659	secondary active sulfate transmembrane transporter activity
ACU16_RS03105	COG3275	phosphorelay sensor kinase activity
ACU16_RS03115	COG0181	hydroxymethylbilane synthase activity
ACU16_RS03140	COG1505	serine-type exopeptidase activity
ACU16_RS03150	COG0436	Aminotransferase
ACU16_RS03160	COG2832	Protein of unknown function (DUF454)
ACU16_RS03180	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ACU16_RS03220	COG5001	Diguanylate cyclase
ACU16_RS03220	COG3300	MHYT domain
ACU16_RS03240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU16_RS03245	COG1077	Cell shape determining protein MreB Mrl
ACU16_RS03250	COG1792	Involved in formation and maintenance of cell shape
ACU16_RS03265	COG0772	Belongs to the SEDS family
ACU16_RS03300	COG3039	Transposase
ACU16_RS03310	COG2963	transposase activity
ACU16_RS03315	COG2801	Transposase and inactivated derivatives
ACU16_RS03320	COG2353	YceI-like domain
ACU16_RS03355	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ACU16_RS03450	COG1063	alcohol dehydrogenase
ACU16_RS03460	COG3039	Transposase
ACU16_RS03470	COG1294	oxidase, subunit
ACU16_RS03475	COG1271	oxidase subunit
ACU16_RS03515	COG2972	Histidine kinase
ACU16_RS03530	COG0531	amino acid
ACU16_RS03545	COG3590	peptidase
ACU16_RS03560	COG0667	Aldo Keto reductase
ACU16_RS03575	COG3384	dioxygenase
ACU16_RS03585	COG1573	uracil-dna glycosylase
ACU16_RS03590	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ACU16_RS03595	COG0025	NhaP-type Na H and K H
ACU16_RS03600	COG1131	(ABC) transporter
ACU16_RS03605	COG0842	Transport permease protein
ACU16_RS03620	COG1404	Belongs to the peptidase S8 family
ACU16_RS03635	COG0745	RESPONSE REGULATOR receiver
ACU16_RS03680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU16_RS03705	COG2205	protein histidine kinase activity
ACU16_RS03705	COG2202	Pas domain
ACU16_RS03730	COG2813	Specifically methylates the guanine in position
ACU16_RS03735	COG1187	pseudouridine synthase activity
ACU16_RS03740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACU16_RS03775	COG0697	spore germination
ACU16_RS03785	COG2011	ABC-type metal ion transport system permease component
ACU16_RS03820	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACU16_RS03830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACU16_RS03850	COG0356	it plays a direct role in the translocation of protons across the membrane
ACU16_RS03860	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACU16_RS03870	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACU16_RS03875	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACU16_RS03880	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACU16_RS03915	COG2801	Transposase and inactivated derivatives
ACU16_RS03920	COG2963	transposase activity
ACU16_RS03930	COG3039	Transposase
ACU16_RS03950	COG2801	Transposase and inactivated derivatives
ACU16_RS03955	COG2963	transposase activity
ACU16_RS03965	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACU16_RS04005	COG0339	signal peptide processing
ACU16_RS04030	COG0546	phosphoglycolate phosphatase activity
ACU16_RS04040	COG1956	GAF domain-containing protein
ACU16_RS04045	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACU16_RS04055	COG0720	synthase
ACU16_RS04060	COG0513	Belongs to the DEAD box helicase family
ACU16_RS04070	COG0625	glutathione transferase activity
ACU16_RS04100	COG0626	cystathionine gamma-synthase activity
ACU16_RS04115	COG0110	maltose O-acetyltransferase activity
ACU16_RS04120	COG0438	transferase activity, transferring glycosyl groups
ACU16_RS04120	COG1216	Glycosyl transferase, family 2
ACU16_RS04125	COG3754	Rhamnan synthesis protein F
ACU16_RS04155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACU16_RS04170	COG0277	FAD linked oxidase domain protein
ACU16_RS04175	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACU16_RS04175	COG0546	phosphoglycolate phosphatase activity
ACU16_RS04190	COG2086	electron transfer activity
ACU16_RS04215	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ACU16_RS04215	COG0662	Cupin 2, conserved barrel domain protein
ACU16_RS04220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACU16_RS04255	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACU16_RS04255	COG3218	ABC-type transport auxiliary lipoprotein component
ACU16_RS04260	COG1127	ABC transporter
ACU16_RS04265	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACU16_RS04280	COG0442	prolyl-tRNA aminoacylation
ACU16_RS04290	COG1183	phosphatidylcholine synthase activity
ACU16_RS04305	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS04325	COG0525	valine-tRNA ligase activity
ACU16_RS04340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACU16_RS04350	COG0795	lipopolysaccharide-transporting ATPase activity
ACU16_RS04365	COG4974	Belongs to the 'phage' integrase family
ACU16_RS04370	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACU16_RS04375	COG0047	phosphoribosylformylglycinamidine synthase activity
ACU16_RS04375	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACU16_RS04380	COG5295	Hep Hag repeat protein
ACU16_RS04385	COG1404	Belongs to the peptidase S8 family
ACU16_RS04390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACU16_RS04395	COG1459	type II secretion system
ACU16_RS04400	COG2165	general secretion pathway protein
ACU16_RS04405	COG4970	Tfp pilus assembly protein FimT
ACU16_RS04410	COG2165	general secretion pathway protein
ACU16_RS04415	COG4795	General secretion pathway protein
ACU16_RS04420	COG3156	type II secretion system protein K
ACU16_RS04425	COG3166	PFAM Fimbrial assembly family protein
ACU16_RS04440	COG1450	Type ii and iii secretion system protein
ACU16_RS04455	COG3293	Transposase
ACU16_RS04465	COG2963	transposase activity
ACU16_RS04470	COG2801	Transposase and inactivated derivatives
ACU16_RS04475	COG3039	Transposase
ACU16_RS04485	COG2188	Transcriptional regulator
ACU16_RS04530	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ACU16_RS04550	COG0242	peptide deformylase activity
ACU16_RS04560	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS04575	COG1228	amidohydrolase
ACU16_RS04580	COG3964	amidohydrolase
ACU16_RS04600	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACU16_RS04605	COG0726	polysaccharide deacetylase
ACU16_RS04620	COG0436	Aminotransferase
ACU16_RS04650	COG2211	Major facilitator Superfamily
ACU16_RS04655	COG1609	Transcriptional regulator
ACU16_RS04660	COG1028	Short-chain dehydrogenase reductase Sdr
ACU16_RS04665	COG2851	Citrate transporter
ACU16_RS04680	COG0642	Histidine kinase
ACU16_RS04690	COG2197	response regulator
ACU16_RS04715	COG0583	DNA-binding transcription factor activity
ACU16_RS04730	COG4191	Histidine kinase
ACU16_RS04745	COG0281	malic enzyme
ACU16_RS04745	COG0280	phosphate acetyltransferase
ACU16_RS04775	COG1560	Kdo2-lipid A biosynthetic process
ACU16_RS04780	COG1519	Transferase
ACU16_RS04785	COG1538	Outer membrane efflux protein
ACU16_RS04790	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACU16_RS04810	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACU16_RS04815	COG0066	3-isopropylmalate dehydratase activity
ACU16_RS04820	COG2226	methyltransferase
ACU16_RS04850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACU16_RS04855	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACU16_RS04860	COG3710	Transcriptional regulator
ACU16_RS04880	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACU16_RS04890	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ACU16_RS04925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACU16_RS04935	COG3781	membrane
ACU16_RS04950	COG1028	Short-chain dehydrogenase reductase Sdr
ACU16_RS04970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACU16_RS04975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACU16_RS05005	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS05015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACU16_RS05040	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACU16_RS05050	COG0352	thiamine-phosphate diphosphorylase activity
ACU16_RS05055	COG1773	rubredoxin
ACU16_RS05060	COG2912	Transglutaminase-like superfamily
ACU16_RS05080	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACU16_RS05100	COG0006	proline dipeptidase activity
ACU16_RS05125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACU16_RS05135	COG0346	lactoylglutathione lyase activity
ACU16_RS05140	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ACU16_RS05145	COG1561	YicC-like family, N-terminal region
ACU16_RS05160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACU16_RS05170	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACU16_RS05195	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACU16_RS05225	COG0714	Associated with various cellular activities
ACU16_RS05245	COG2304	oxidoreductase activity
ACU16_RS05270	COG2963	transposase activity
ACU16_RS05275	COG1301	dicarboxylic acid transport
ACU16_RS05280	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACU16_RS05290	COG1376	ErfK ybiS ycfS ynhG family protein
ACU16_RS05360	COG0642	Histidine kinase
ACU16_RS05380	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ACU16_RS05385	COG4149	molybdate abc transporter
ACU16_RS05390	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACU16_RS05395	COG3453	Protein conserved in bacteria
ACU16_RS05395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACU16_RS05410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACU16_RS05425	COG0126	phosphoglycerate kinase activity
ACU16_RS05435	COG0469	pyruvate kinase activity
ACU16_RS05440	COG3588	fructose-bisphosphate aldolase
ACU16_RS05445	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ACU16_RS05480	COG2198	Histidine kinase
ACU16_RS05480	COG0784	Response regulator, receiver
ACU16_RS05480	COG2205	protein histidine kinase activity
ACU16_RS05500	COG0175	sulfate reduction
ACU16_RS05505	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACU16_RS05510	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACU16_RS05515	COG0175	sulfate reduction
ACU16_RS05520	COG0529	Catalyzes the synthesis of activated sulfate
ACU16_RS05520	COG2895	sulfate adenylyltransferase (ATP) activity
ACU16_RS05530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU16_RS05535	COG0308	aminopeptidase N
ACU16_RS05545	COG3039	Transposase
ACU16_RS05555	COG2801	Transposase and inactivated derivatives
ACU16_RS05560	COG2963	transposase activity
ACU16_RS05570	COG1970	mechanosensitive ion channel activity
ACU16_RS05595	COG0471	metal ion transport
ACU16_RS05595	COG3273	potassium ion transport
ACU16_RS05605	COG2022	thiamine diphosphate biosynthetic process
ACU16_RS05640	COG3291	Pkd domain containing protein
ACU16_RS05650	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACU16_RS05655	COG0671	phosphoesterase, PA-phosphatase related
ACU16_RS05660	COG0438	transferase activity, transferring glycosyl groups
ACU16_RS05670	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ACU16_RS05685	COG4783	chaperone-mediated protein folding
ACU16_RS05700	COG0473	3-isopropylmalate dehydrogenase activity
ACU16_RS05745	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACU16_RS05785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACU16_RS05810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACU16_RS05815	COG3039	Transposase
ACU16_RS05820	COG0631	protein serine/threonine phosphatase activity
ACU16_RS05835	COG0859	PFAM glycosyl transferase family 9
ACU16_RS05840	COG3642	lipopolysaccharide core region biosynthetic process
ACU16_RS05845	COG1234	tRNA 3'-trailer cleavage
ACU16_RS05850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACU16_RS05860	COG0315	cyclic pyranopterin monophosphate synthase activity
ACU16_RS05865	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ACU16_RS05870	COG0314	molybdopterin synthase activity
ACU16_RS05885	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACU16_RS05895	COG0537	adenosine 5'-monophosphoramidase activity
ACU16_RS05915	COG0714	Associated with various cellular activities
ACU16_RS05930	COG2963	transposase activity
ACU16_RS05945	COG1399	metal-binding, possibly nucleic acid-binding protein
ACU16_RS05970	COG1028	Short-chain dehydrogenase reductase Sdr
ACU16_RS05975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACU16_RS05985	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACU16_RS05990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACU16_RS06025	COG3039	Transposase
ACU16_RS06035	COG3829	transcription factor binding
ACU16_RS06050	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACU16_RS06055	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS06100	COG0678	peroxiredoxin activity
ACU16_RS06120	COG0330	HflC and HflK could
ACU16_RS06125	COG0330	HflC and HflK could
ACU16_RS06140	COG0308	aminopeptidase N
ACU16_RS06150	COG1028	Short-chain dehydrogenase reductase Sdr
ACU16_RS06195	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ACU16_RS06230	COG0732	type I restriction modification DNA specificity domain
ACU16_RS06305	COG0587	DNA-directed DNA polymerase activity
ACU16_RS06320	COG1297	OPT oligopeptide transporter protein
ACU16_RS06330	COG0823	Involved in the tonB-independent uptake of proteins
ACU16_RS06330	COG1506	peptidase
ACU16_RS06340	COG2207	Transcriptional regulator
ACU16_RS06340	COG1917	Cupin 2, conserved barrel domain protein
ACU16_RS06355	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS06360	COG2963	transposase activity
ACU16_RS06420	COG0019	diaminopimelate decarboxylase activity
ACU16_RS06430	COG2814	Major facilitator Superfamily
ACU16_RS06435	COG4264	IucA IucC family
ACU16_RS06445	COG4772	TonB-dependent receptor
ACU16_RS06460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACU16_RS06460	COG4651	solute:proton antiporter activity
ACU16_RS06490	COG0488	(ABC) transporter
ACU16_RS06510	COG2755	lipolytic protein G-D-S-L family
ACU16_RS06510	COG0657	acetylesterase activity
ACU16_RS06525	COG0477	Major facilitator Superfamily
ACU16_RS06540	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACU16_RS06575	COG2255	four-way junction helicase activity
ACU16_RS06580	COG0824	Thioesterase
ACU16_RS06600	COG0823	Involved in the tonB-independent uptake of proteins
ACU16_RS06605	COG2885	chlorophyll binding
ACU16_RS06615	COG0602	queuosine metabolic process
ACU16_RS06625	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACU16_RS06655	COG0840	transmembrane signaling receptor activity
ACU16_RS06665	COG1187	pseudouridine synthase activity
ACU16_RS06680	COG0514	ATP-dependent DNA helicase (RecQ)
ACU16_RS06685	COG0783	Belongs to the Dps family
ACU16_RS06690	COG1643	Atp-dependent helicase
ACU16_RS06740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACU16_RS06750	COG1215	transferase activity, transferring glycosyl groups
ACU16_RS06755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACU16_RS06765	COG1199	ATP-dependent helicase activity
ACU16_RS06785	COG0189	ligase activity
ACU16_RS06800	COG0835	chemotaxis
ACU16_RS06805	COG0840	transmembrane signaling receptor activity
ACU16_RS06810	COG2198	Histidine kinase
ACU16_RS06810	COG0784	Response regulator, receiver
ACU16_RS06810	COG0643	Histidine kinase
ACU16_RS06840	COG2304	oxidoreductase activity
ACU16_RS06845	COG1446	asparaginase
ACU16_RS06850	COG3142	Participates in the control of copper homeostasis
ACU16_RS06890	COG3537	Alpha-1,2-mannosidase
ACU16_RS06915	COG1472	Belongs to the glycosyl hydrolase 3 family
ACU16_RS06925	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ACU16_RS06930	COG1388	LysM domain
ACU16_RS06930	COG3858	chitin binding
ACU16_RS06945	COG0837	glucose binding
ACU16_RS06950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACU16_RS06960	COG0494	nUDIX hydrolase
ACU16_RS06970	COG3956	TIGRFAM MazG family protein
ACU16_RS06975	COG1742	UPF0060 membrane protein
ACU16_RS06980	COG0330	HflC and HflK could
ACU16_RS06995	COG0509	glycine decarboxylation via glycine cleavage system
ACU16_RS07020	COG1960	acyl-CoA dehydrogenase activity
ACU16_RS07030	COG1309	transcriptional regulator
ACU16_RS07035	COG4771	TonB-dependent receptor
ACU16_RS07045	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ACU16_RS07055	COG0463	Glycosyl transferase, family 2
ACU16_RS07060	COG0516	GMP reductase activity
ACU16_RS07060	COG0517	IMP dehydrogenase activity
ACU16_RS07085	COG1272	protein, Hemolysin III
ACU16_RS07095	COG0739	heme binding
ACU16_RS07100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACU16_RS07105	COG0626	cystathionine gamma-synthase activity
ACU16_RS07115	COG1760	l-serine dehydratase
ACU16_RS07140	COG2353	YceI-like domain
ACU16_RS07145	COG0784	Response regulator, receiver
ACU16_RS07145	COG2205	protein histidine kinase activity
ACU16_RS07145	COG2198	Histidine kinase
ACU16_RS07150	COG0784	Response regulator, receiver
ACU16_RS07150	COG5002	protein histidine kinase activity
ACU16_RS07160	COG3039	Transposase
ACU16_RS07195	COG3250	beta-galactosidase activity
ACU16_RS07220	COG1960	acyl-CoA dehydrogenase activity
ACU16_RS07225	COG1024	Enoyl-CoA hydratase
ACU16_RS07245	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACU16_RS07245	COG1024	Enoyl-CoA hydratase
ACU16_RS07265	COG0481	GTPase activity
ACU16_RS07270	COG0681	Belongs to the peptidase S26 family
ACU16_RS07290	COG1381	Involved in DNA repair and RecF pathway recombination
ACU16_RS07305	COG2954	triphosphatase activity
ACU16_RS07310	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACU16_RS07315	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
ACU16_RS07320	COG3046	protein related to deoxyribodipyrimidine photolyase
ACU16_RS07330	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ACU16_RS07335	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ACU16_RS07340	COG1278	Cold shock
ACU16_RS07360	COG1201	RNA secondary structure unwinding
ACU16_RS07365	COG1793	dna ligase
ACU16_RS07375	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ACU16_RS07375	COG1793	dna ligase
ACU16_RS07390	COG3706	GGDEF domain
ACU16_RS07405	COG0183	Belongs to the thiolase family
ACU16_RS07420	COG1451	nucleotide metabolic process
ACU16_RS07435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACU16_RS07470	COG1047	Peptidyl-prolyl cis-trans
ACU16_RS07480	COG2824	Alkylphosphonate utilization operon protein PhnA
ACU16_RS07490	COG1902	pentaerythritol trinitrate reductase activity
ACU16_RS07525	COG0392	lysyltransferase activity
ACU16_RS07525	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ACU16_RS07535	COG0251	oxidation-reduction process
ACU16_RS07540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACU16_RS07555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACU16_RS07580	COG1595	DNA-templated transcription, initiation
ACU16_RS07600	COG2878	Part of a membrane complex involved in electron transport
ACU16_RS07610	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACU16_RS07610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACU16_RS07620	COG0346	lactoylglutathione lyase activity
ACU16_RS07625	COG0833	amino acid
ACU16_RS07630	COG2040	homocysteine
ACU16_RS07640	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ACU16_RS07660	COG1695	Transcriptional regulator
ACU16_RS07680	COG1981	membrane
ACU16_RS07695	COG0825	malonyl-CoA metabolic process
ACU16_RS07715	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACU16_RS07720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACU16_RS07725	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACU16_RS07735	COG0750	zinc metalloprotease
ACU16_RS07740	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ACU16_RS07745	COG0575	Belongs to the CDS family
ACU16_RS07755	COG0233	cytoplasmic translational termination
ACU16_RS07770	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACU16_RS07830	COG1393	Belongs to the ArsC family
ACU16_RS07840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACU16_RS07845	COG0367	asparagine synthase
ACU16_RS07855	COG4774	siderophore transport
ACU16_RS07875	COG2207	Transcriptional regulator
ACU16_RS07890	COG1566	PFAM secretion protein HlyD family protein
ACU16_RS07895	COG2814	Major facilitator Superfamily
ACU16_RS07990	COG0386	Belongs to the glutathione peroxidase family
ACU16_RS08045	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACU16_RS08050	COG0084	hydrolase, TatD family'
ACU16_RS08065	COG1960	acyl-CoA dehydrogenase activity
ACU16_RS08080	COG0367	asparagine synthase
ACU16_RS08090	COG0305	Participates in initiation and elongation during chromosome replication
ACU16_RS08095	COG0415	Belongs to the DNA photolyase family
ACU16_RS08110	COG1028	Short-chain dehydrogenase reductase Sdr
ACU16_RS08130	COG3706	GGDEF domain
ACU16_RS08140	COG3293	Transposase
ACU16_RS08145	COG0489	protein tyrosine kinase activity
ACU16_RS08150	COG0717	Belongs to the dCTP deaminase family
ACU16_RS08175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACU16_RS08185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACU16_RS08200	COG3039	Transposase
ACU16_RS08205	COG0433	COG0433 Predicted ATPase
ACU16_RS08230	COG2890	protein-(glutamine-N5) methyltransferase activity
ACU16_RS08235	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACU16_RS08240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACU16_RS08245	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACU16_RS08260	COG0101	tRNA pseudouridine synthase activity
ACU16_RS08265	COG0135	phosphoribosylanthranilate isomerase activity
ACU16_RS08275	COG0133	tryptophan synthase activity
ACU16_RS08290	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ACU16_RS08295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACU16_RS08330	COG0149	triose-phosphate isomerase activity
ACU16_RS08335	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACU16_RS08345	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACU16_RS08355	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACU16_RS08360	COG0649	NAD binding
ACU16_RS08365	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ACU16_RS08370	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACU16_RS08375	COG1034	ATP synthesis coupled electron transport
ACU16_RS08380	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACU16_RS08410	COG1007	ATP synthesis coupled electron transport
ACU16_RS08420	COG0779	Required for maturation of 30S ribosomal subunits
ACU16_RS08425	COG0195	Participates in both transcription termination and antitermination
ACU16_RS08430	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACU16_RS08445	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACU16_RS08450	COG1185	polyribonucleotide nucleotidyltransferase activity
ACU16_RS08485	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACU16_RS08495	COG2095	MarC family integral membrane protein
ACU16_RS08505	COG1611	Belongs to the LOG family
ACU16_RS08545	COG4969	Belongs to the N-Me-Phe pilin family
ACU16_RS08550	COG0556	nucleotide-excision repair
ACU16_RS08565	COG2963	transposase activity
ACU16_RS08575	COG2963	transposase activity
ACU16_RS08580	COG2801	Transposase and inactivated derivatives
ACU16_RS08595	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ACU16_RS08605	COG2986	histidine ammonia-lyase
ACU16_RS08610	COG1228	amidohydrolase
ACU16_RS08655	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACU16_RS08660	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ACU16_RS08665	COG0077	Prephenate dehydratase
ACU16_RS08665	COG1605	Chorismate mutase
ACU16_RS08670	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACU16_RS08685	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACU16_RS08690	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACU16_RS08695	COG0583	DNA-binding transcription factor activity
ACU16_RS08715	COG2801	Transposase and inactivated derivatives
ACU16_RS08725	COG2963	transposase activity
ACU16_RS08740	COG3039	Transposase
ACU16_RS08750	COG3039	Transposase
ACU16_RS08780	COG0840	transmembrane signaling receptor activity
ACU16_RS08795	COG5002	protein histidine kinase activity
ACU16_RS08795	COG2205	protein histidine kinase activity
ACU16_RS08795	COG0784	Response regulator, receiver
ACU16_RS08800	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ACU16_RS08820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACU16_RS08840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACU16_RS08855	COG1595	DNA-templated transcription, initiation
ACU16_RS08905	COG2244	polysaccharide biosynthetic process
ACU16_RS08935	COG2264	protein methyltransferase activity
ACU16_RS08945	COG0438	transferase activity, transferring glycosyl groups
ACU16_RS08965	COG1132	(ABC) transporter
ACU16_RS08970	COG2271	Major facilitator Superfamily
ACU16_RS08975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACU16_RS08990	COG1253	flavin adenine dinucleotide binding
ACU16_RS09025	COG0504	CTP synthase activity
ACU16_RS09030	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ACU16_RS09040	COG0148	phosphopyruvate hydratase activity
ACU16_RS09045	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ACU16_RS09055	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACU16_RS09070	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACU16_RS09075	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACU16_RS09080	COG1238	metal cluster binding
ACU16_RS09095	COG1534	Rna-binding protein
ACU16_RS09100	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ACU16_RS09110	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACU16_RS09125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACU16_RS09130	COG1546	Belongs to the CinA family
ACU16_RS09145	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACU16_RS09150	COG2137	regulation of response to DNA damage stimulus
ACU16_RS09155	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACU16_RS09160	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ACU16_RS09175	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACU16_RS09195	COG3293	Transposase
ACU16_RS09205	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACU16_RS09235	COG2166	iron-sulfur cluster assembly
ACU16_RS09250	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACU16_RS09255	COG0137	argininosuccinate synthase activity
ACU16_RS09265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACU16_RS09270	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACU16_RS09285	COG0165	Argininosuccinate lyase
ACU16_RS09325	COG1294	oxidase, subunit
ACU16_RS09330	COG1271	oxidase subunit
ACU16_RS09340	COG4988	ABC transporter
ACU16_RS09345	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ACU16_RS09405	COG4133	protoheme IX ABC transporter activity
ACU16_RS09410	COG0436	Aminotransferase
ACU16_RS09430	COG1187	pseudouridine synthase activity
ACU16_RS09435	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACU16_RS09440	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACU16_RS09445	COG2350	Protein conserved in bacteria
ACU16_RS09475	COG1175	transmembrane transport
ACU16_RS09480	COG0395	ABC-type sugar transport system, permease component
ACU16_RS09500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACU16_RS09505	COG2957	Belongs to the agmatine deiminase family
ACU16_RS09520	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACU16_RS09525	COG0539	negative regulation of cytoplasmic translation
ACU16_RS09530	COG0776	regulation of translation
ACU16_RS09540	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ACU16_RS09545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACU16_RS09555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACU16_RS09560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACU16_RS09560	COG0475	glutathione-regulated potassium exporter activity
ACU16_RS09565	COG0475	glutathione-regulated potassium exporter activity
ACU16_RS09565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACU16_RS09580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACU16_RS09590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACU16_RS09590	COG0519	Catalyzes the synthesis of GMP from XMP
ACU16_RS09595	COG3002	Belongs to the UPF0753 family
ACU16_RS09600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACU16_RS09605	COG0583	DNA-binding transcription factor activity
ACU16_RS09625	COG0583	DNA-binding transcription factor activity
ACU16_RS09630	COG0583	DNA-binding transcription factor activity
ACU16_RS09645	COG2201	protein-glutamate methylesterase activity
ACU16_RS09650	COG1914	H( )-stimulated, divalent metal cation uptake system
ACU16_RS09670	COG0668	transmembrane transport
ACU16_RS09695	COG1028	Short-chain dehydrogenase reductase Sdr
ACU16_RS09700	COG1183	phosphatidylcholine synthase activity
ACU16_RS09710	COG3243	poly(R)-hydroxyalkanoic acid synthase
ACU16_RS09725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU16_RS09725	COG0723	plastoquinol--plastocyanin reductase activity
ACU16_RS09735	COG2183	response to ionizing radiation
ACU16_RS09740	COG2205	protein histidine kinase activity
ACU16_RS09740	COG0784	Response regulator, receiver
ACU16_RS09785	COG3039	Transposase
ACU16_RS09840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU16_RS09845	COG3039	Transposase
ACU16_RS09870	COG3039	Transposase
ACU16_RS09875	COG0800	Aldolase
ACU16_RS09880	COG0129	dihydroxy-acid dehydratase activity
ACU16_RS09885	COG0363	glucosamine-6-phosphate deaminase activity
ACU16_RS09895	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACU16_RS09905	COG0354	folic acid binding
ACU16_RS09915	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ACU16_RS09930	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACU16_RS09945	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACU16_RS09965	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS09975	COG0811	peptide transport
ACU16_RS09990	COG1663	tetraacyldisaccharide 4'-kinase activity
ACU16_RS10000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACU16_RS10010	COG0322	excinuclease ABC activity
ACU16_RS10035	COG0582	viral genome integration into host DNA
ACU16_RS10110	COG0037	tRNA processing
ACU16_RS10125	COG2234	aminopeptidase activity
ACU16_RS10145	COG3039	Transposase
ACU16_RS10155	COG2963	transposase activity
ACU16_RS10160	COG2801	Transposase and inactivated derivatives
ACU16_RS10180	COG3039	Transposase
ACU16_RS10205	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACU16_RS10225	COG1054	Belongs to the UPF0176 family
ACU16_RS10235	COG1530	ribonuclease E activity
ACU16_RS10245	COG3064	Membrane
ACU16_RS10250	COG0428	transporter
ACU16_RS10255	COG0428	transporter
ACU16_RS10265	COG2154	pterin-4-alpha-carbinolamine dehydratase
ACU16_RS10320	COG2963	transposase activity
ACU16_RS10370	COG3039	Transposase
ACU16_RS10420	COG3039	Transposase
ACU16_RS10465	COG0631	protein serine/threonine phosphatase activity
ACU16_RS10470	COG0515	serine threonine protein kinase
ACU16_RS10495	COG1858	cytochrome C peroxidase
ACU16_RS10560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU16_RS10565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU16_RS10630	COG2201	protein-glutamate methylesterase activity
ACU16_RS10670	COG4566	intracellular signal transduction
ACU16_RS10690	COG5001	Diguanylate cyclase
ACU16_RS10730	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACU16_RS10730	COG1648	precorrin-2 dehydrogenase activity
ACU16_RS10755	COG0746	molybdenum cofactor guanylyltransferase activity
ACU16_RS10795	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACU16_RS10805	COG0303	'Molybdopterin
ACU16_RS10810	COG1160	GTP binding
ACU16_RS10815	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU16_RS10835	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACU16_RS10850	COG1024	Enoyl-CoA hydratase
ACU16_RS10850	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACU16_RS10855	COG0183	Belongs to the thiolase family
ACU16_RS10860	COG0038	chloride channel
ACU16_RS10880	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACU16_RS10900	COG1674	ftsk spoiiie
ACU16_RS10905	COG0492	ferredoxin-NADP+ reductase activity
ACU16_RS10935	COG0542	response to heat
ACU16_RS10950	COG0482	sulfurtransferase activity
ACU16_RS10980	COG4585	Histidine kinase
ACU16_RS10990	COG5002	protein histidine kinase activity
ACU16_RS11010	COG0835	chemotaxis
ACU16_RS11010	COG0784	Response regulator, receiver
ACU16_RS11020	COG1558	bacterial-type flagellum-dependent cell motility
ACU16_RS11025	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ACU16_RS11035	COG4787	bacterial-type flagellum-dependent cell motility
ACU16_RS11045	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ACU16_RS11050	COG1706	bacterial-type flagellum-dependent cell motility
ACU16_RS11070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACU16_RS11075	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ACU16_RS11105	COG2201	protein-glutamate methylesterase activity
ACU16_RS11125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACU16_RS11130	COG4221	oxidoreductase activity
ACU16_RS11135	COG1028	Short-chain dehydrogenase reductase Sdr
ACU16_RS11165	COG3039	Transposase
ACU16_RS11180	COG1677	Flagellar hook-basal body complex protein FliE
ACU16_RS11230	COG3190	flagellar
ACU16_RS11245	COG1684	flagellar biosynthetic protein fliR
ACU16_RS11300	COG0784	Response regulator, receiver
ACU16_RS11300	COG0643	Histidine kinase
ACU16_RS11300	COG2198	Histidine kinase
ACU16_RS11340	COG2963	transposase activity
ACU16_RS11430	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ACU16_RS11435	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS11465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACU16_RS11470	COG4774	siderophore transport
ACU16_RS11485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACU16_RS11490	COG1360	Flagellar Motor Protein
ACU16_RS11495	COG1192	Involved in chromosome partitioning
ACU16_RS11500	COG0835	chemotaxis
ACU16_RS11510	COG0745	RESPONSE REGULATOR receiver
ACU16_RS11520	COG0840	transmembrane signaling receptor activity
ACU16_RS11530	COG0840	transmembrane signaling receptor activity
ACU16_RS11535	COG0840	transmembrane signaling receptor activity
ACU16_RS11540	COG0840	transmembrane signaling receptor activity
ACU16_RS11545	COG0840	transmembrane signaling receptor activity
ACU16_RS11550	COG0840	transmembrane signaling receptor activity
ACU16_RS11555	COG0840	transmembrane signaling receptor activity
ACU16_RS11560	COG0840	transmembrane signaling receptor activity
ACU16_RS11565	COG0840	transmembrane signaling receptor activity
ACU16_RS11570	COG0840	transmembrane signaling receptor activity
ACU16_RS11585	COG0835	chemotaxis
ACU16_RS11595	COG0840	transmembrane signaling receptor activity
ACU16_RS11620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACU16_RS11645	COG0318	PFAM AMP-dependent synthetase and ligase
ACU16_RS11650	COG1024	Enoyl-CoA hydratase
ACU16_RS11655	COG0784	Response regulator, receiver
ACU16_RS11655	COG2198	Histidine kinase
ACU16_RS11655	COG2205	protein histidine kinase activity
ACU16_RS11670	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACU16_RS11675	COG3279	Response regulator of the LytR AlgR family
ACU16_RS11685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACU16_RS11695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACU16_RS11700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACU16_RS11710	COG0505	Belongs to the CarA family
ACU16_RS11715	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACU16_RS11720	COG2258	MOSC domain
ACU16_RS11725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACU16_RS11775	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACU16_RS11795	COG0277	FAD linked oxidase domain protein
ACU16_RS11800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACU16_RS11810	COG0531	amino acid
ACU16_RS11815	COG0531	amino acid
ACU16_RS11820	COG0235	Class ii aldolase
ACU16_RS11825	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ACU16_RS11850	COG0140	phosphoribosyl-ATP diphosphatase activity
ACU16_RS11850	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACU16_RS11860	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACU16_RS11870	COG0131	Imidazoleglycerol-phosphate dehydratase
ACU16_RS11870	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACU16_RS11885	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACU16_RS11895	COG0124	histidyl-tRNA synthetase
ACU16_RS11910	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACU16_RS11925	COG2963	transposase activity
ACU16_RS11930	COG2801	Transposase and inactivated derivatives
ACU16_RS11955	COG2963	transposase activity
ACU16_RS11960	COG2801	Transposase and inactivated derivatives
ACU16_RS11985	COG1012	belongs to the aldehyde dehydrogenase family
ACU16_RS12005	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACU16_RS12010	COG0697	spore germination
ACU16_RS12015	COG1794	racemase activity, acting on amino acids and derivatives
ACU16_RS12025	COG0671	phosphoesterase, PA-phosphatase related
ACU16_RS12040	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ACU16_RS12045	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU16_RS12050	COG3706	GGDEF domain
ACU16_RS12050	COG5001	Diguanylate cyclase
ACU16_RS12050	COG2203	Gaf domain
ACU16_RS12050	COG4251	negative regulation of phosphorylation
ACU16_RS12060	COG1472	Belongs to the glycosyl hydrolase 3 family
ACU16_RS12085	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ACU16_RS12105	COG0617	tRNA 3'-terminal CCA addition
ACU16_RS12115	COG1469	GTP cyclohydrolase I activity
ACU16_RS12120	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACU16_RS12125	COG0477	Major facilitator Superfamily
ACU16_RS12135	COG1070	Carbohydrate kinase
ACU16_RS12160	COG0800	Aldolase
ACU16_RS12165	COG4948	Mandelate Racemase Muconate Lactonizing
ACU16_RS12175	COG3734	2-keto-3-deoxy-galactonokinase
ACU16_RS12180	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ACU16_RS12190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACU16_RS12205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACU16_RS12210	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ACU16_RS12220	COG0352	thiamine-phosphate diphosphorylase activity
ACU16_RS12220	COG0351	phosphomethylpyrimidine kinase
ACU16_RS12250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACU16_RS12270	COG3318	Belongs to the UPF0149 family
ACU16_RS12270	COG3012	SEC-C Motif Domain Protein
ACU16_RS12275	COG0583	DNA-binding transcription factor activity
ACU16_RS12280	COG1741	Belongs to the pirin family
ACU16_RS12320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACU16_RS12325	COG0402	S-adenosylhomocysteine deaminase activity
ACU16_RS12340	COG1509	lysine 2,3-aminomutase activity
ACU16_RS12345	COG5001	Diguanylate cyclase
ACU16_RS12345	COG3300	MHYT domain
ACU16_RS12360	COG0483	inositol monophosphate 1-phosphatase activity
ACU16_RS12365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACU16_RS12385	COG0488	(ABC) transporter
ACU16_RS12390	COG0513	Belongs to the DEAD box helicase family
ACU16_RS12400	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ACU16_RS12410	COG0625	glutathione transferase activity
ACU16_RS12415	COG1278	Cold shock
ACU16_RS12420	COG1671	Belongs to the UPF0178 family
ACU16_RS12425	COG4681	YaeQ
ACU16_RS12430	COG2081	HI0933 family
ACU16_RS12450	COG1028	Short-chain dehydrogenase reductase Sdr
ACU16_RS12470	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACU16_RS12475	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACU16_RS12480	COG0802	atpase or kinase
ACU16_RS12485	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACU16_RS12485	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACU16_RS12505	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACU16_RS12565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACU16_RS12665	COG2801	Transposase and inactivated derivatives
ACU16_RS12680	COG0835	chemotaxis
ACU16_RS12685	COG0840	transmembrane signaling receptor activity
ACU16_RS12710	COG2969	positive regulation of protein catabolic process
ACU16_RS12715	COG0625	glutathione transferase activity
ACU16_RS12720	COG2857	Cytochrome c1
ACU16_RS12725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ACU16_RS12730	COG0723	plastoquinol--plastocyanin reductase activity
ACU16_RS12735	COG0741	lytic transglycosylase activity
ACU16_RS12755	COG1702	phosphate starvation-inducible protein PhoH
ACU16_RS12775	COG4535	Mg2 and Co2 transporter CorC
ACU16_RS12790	COG1012	belongs to the aldehyde dehydrogenase family
ACU16_RS12795	COG1177	transmembrane transport
ACU16_RS12800	COG1176	ABC-type spermidine putrescine transport system, permease component I
ACU16_RS12805	COG3842	ATPase activity
ACU16_RS12825	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ACU16_RS12850	COG2201	protein-glutamate methylesterase activity
ACU16_RS12895	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACU16_RS12900	COG0174	glutamine synthetase
ACU16_RS12905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU16_RS12915	COG0477	Major facilitator Superfamily
ACU16_RS12920	COG0243	molybdopterin cofactor binding
ACU16_RS12935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACU16_RS12940	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS12960	COG1121	(ABC) transporter
ACU16_RS12965	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS12975	COG2733	membrane
ACU16_RS12980	COG5002	protein histidine kinase activity
ACU16_RS12980	COG2205	protein histidine kinase activity
ACU16_RS12980	COG0784	Response regulator, receiver
ACU16_RS12990	COG0477	Major facilitator Superfamily
ACU16_RS13005	COG2902	Dehydrogenase
ACU16_RS13015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU16_RS13020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU16_RS13030	COG1609	Transcriptional regulator
ACU16_RS13035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACU16_RS13035	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACU16_RS13040	COG1105	Belongs to the carbohydrate kinase PfkB family
ACU16_RS13045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACU16_RS13045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACU16_RS13065	COG3039	Transposase
ACU16_RS13100	COG2963	transposase activity
ACU16_RS13135	COG2963	transposase activity
ACU16_RS13140	COG2801	Transposase and inactivated derivatives
ACU16_RS13170	COG3039	Transposase
ACU16_RS13195	COG2963	transposase activity
ACU16_RS13220	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACU16_RS13230	COG1862	Preprotein translocase
ACU16_RS13235	COG0343	queuine tRNA-ribosyltransferase activity
ACU16_RS13295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACU16_RS13310	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACU16_RS13315	COG0742	ribosomal rna small subunit methyltransferase
ACU16_RS13320	COG0326	Molecular chaperone. Has ATPase activity
ACU16_RS13325	COG2801	Transposase and inactivated derivatives
ACU16_RS13330	COG2963	transposase activity
ACU16_RS13340	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS13380	COG4206	TonB-dependent receptor
ACU16_RS13435	COG0531	amino acid
ACU16_RS13450	COG0006	proline dipeptidase activity
ACU16_RS13460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACU16_RS13475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU16_RS13480	COG3938	Belongs to the proline racemase family
ACU16_RS13490	COG0552	protein localization to endoplasmic reticulum
ACU16_RS13500	COG1194	a g-specific adenine glycosylase
ACU16_RS13510	COG4191	Histidine kinase
ACU16_RS13510	COG0784	Response regulator, receiver
ACU16_RS13515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACU16_RS13540	COG3040	lipid binding
ACU16_RS13550	COG1960	acyl-CoA dehydrogenase activity
ACU16_RS13560	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACU16_RS13595	COG0438	transferase activity, transferring glycosyl groups
ACU16_RS13605	COG0438	transferase activity, transferring glycosyl groups
ACU16_RS13610	COG0438	transferase activity, transferring glycosyl groups
ACU16_RS13665	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACU16_RS13680	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACU16_RS13690	COG2963	transposase activity
ACU16_RS13705	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ACU16_RS13715	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ACU16_RS13725	COG2963	transposase activity
ACU16_RS13730	COG2801	Transposase and inactivated derivatives
ACU16_RS13740	COG3115	cell septum assembly
ACU16_RS13760	COG0360	Binds together with S18 to 16S ribosomal RNA
ACU16_RS13765	COG0316	Belongs to the HesB IscA family
ACU16_RS13795	COG0288	reversible hydration of carbon dioxide
ACU16_RS13810	COG3844	kynureninase activity
ACU16_RS13820	COG2925	Exonuclease
ACU16_RS13830	COG0667	Aldo Keto reductase
ACU16_RS13850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACU16_RS13850	COG0116	Belongs to the methyltransferase superfamily
ACU16_RS13890	COG0494	nUDIX hydrolase
ACU16_RS13900	COG1024	Enoyl-CoA hydratase
ACU16_RS13910	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACU16_RS13940	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACU16_RS13945	COG0573	inorganic phosphate transmembrane transporter activity
ACU16_RS13960	COG0704	Plays a role in the regulation of phosphate uptake
ACU16_RS13970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACU16_RS13980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACU16_RS13990	COG0557	exoribonuclease II activity
ACU16_RS14010	COG1960	acyl-CoA dehydrogenase activity
ACU16_RS14015	COG2226	methyltransferase
ACU16_RS14035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU16_RS14045	COG1609	Transcriptional regulator
ACU16_RS14060	COG3293	Transposase
ACU16_RS14070	COG2900	Belongs to the SlyX family
ACU16_RS14085	COG0386	Belongs to the glutathione peroxidase family
ACU16_RS14095	COG1725	Transcriptional regulator
ACU16_RS14100	COG1131	(ABC) transporter
ACU16_RS14160	COG2850	peptidyl-arginine hydroxylation
ACU16_RS14195	COG1132	(ABC) transporter
ACU16_RS14200	COG0583	DNA-binding transcription factor activity
ACU16_RS14210	COG2963	transposase activity
ACU16_RS14215	COG2801	Transposase and inactivated derivatives
ACU16_RS14250	COG3039	Transposase
ACU16_RS14280	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ACU16_RS14285	COG0484	heat shock protein binding
ACU16_RS14290	COG0443	Heat shock 70 kDa protein
ACU16_RS14295	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACU16_RS14305	COG0497	DNA recombination
ACU16_RS14315	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU16_RS14320	COG2914	Belongs to the UPF0125 (RnfH) family
ACU16_RS14330	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACU16_RS14345	COG3590	peptidase
ACU16_RS14390	COG2801	Transposase and inactivated derivatives
ACU16_RS14415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU16_RS14420	COG2311	Membrane
ACU16_RS14425	COG1047	Peptidyl-prolyl cis-trans
ACU16_RS14435	COG0791	NLP P60 protein
ACU16_RS14445	COG4106	trans-aconitate 2-methyltransferase activity
ACU16_RS14450	COG1301	dicarboxylic acid transport
ACU16_RS14455	COG1785	Belongs to the alkaline phosphatase family
ACU16_RS14460	COG0037	tRNA processing
ACU16_RS14465	COG1722	exodeoxyribonuclease VII activity
ACU16_RS14470	COG0142	geranyltranstransferase activity
ACU16_RS14475	COG4104	PAAR repeat-containing protein
ACU16_RS14495	COG0312	modulator of DNA gyrase
ACU16_RS14500	COG3028	Belongs to the UPF0307 family
ACU16_RS14505	COG0312	modulator of DNA gyrase
ACU16_RS14515	COG3164	Protein of unknown function
ACU16_RS14530	COG2968	Membrane
ACU16_RS14545	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACU16_RS14570	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACU16_RS14595	COG3118	belongs to the thioredoxin family
ACU16_RS14650	COG1132	(ABC) transporter
ACU16_RS14680	COG0745	RESPONSE REGULATOR receiver
ACU16_RS14685	COG5000	phosphorelay sensor kinase activity
ACU16_RS14685	COG5002	protein histidine kinase activity
ACU16_RS14690	COG0475	glutathione-regulated potassium exporter activity
ACU16_RS14700	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACU16_RS14715	COG1187	pseudouridine synthase activity
ACU16_RS14720	COG5001	Diguanylate cyclase
ACU16_RS14720	COG5002	protein histidine kinase activity
ACU16_RS14765	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ACU16_RS14830	COG0735	belongs to the Fur family
ACU16_RS14835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACU16_RS14870	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACU16_RS14880	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACU16_RS14890	COG0643	Histidine kinase
ACU16_RS14890	COG2198	Histidine kinase
ACU16_RS14895	COG0840	transmembrane signaling receptor activity
ACU16_RS14900	COG0835	chemotaxis
ACU16_RS14905	COG2200	EAL domain
ACU16_RS14905	COG2202	Pas domain
ACU16_RS14905	COG2199	diguanylate cyclase activity
ACU16_RS14910	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACU16_RS14960	COG2963	transposase activity
ACU16_RS14985	COG1515	deoxyribonuclease V activity
ACU16_RS14990	COG1741	Belongs to the pirin family
ACU16_RS15070	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACU16_RS15080	COG2963	transposase activity
ACU16_RS15085	COG2801	Transposase and inactivated derivatives
ACU16_RS15095	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACU16_RS15110	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACU16_RS15130	COG1741	Belongs to the pirin family
ACU16_RS15135	COG1966	Carbon starvation protein
ACU16_RS15140	COG2879	small protein
ACU16_RS15170	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACU16_RS15175	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACU16_RS15180	COG2080	2 iron, 2 sulfur cluster binding
ACU16_RS15185	COG3039	Transposase
ACU16_RS15195	COG1028	Short-chain dehydrogenase reductase Sdr
ACU16_RS15195	COG0604	alcohol dehydrogenase
ACU16_RS15195	COG3321	synthase
ACU16_RS15200	COG4251	negative regulation of phosphorylation
ACU16_RS15200	COG3706	GGDEF domain
ACU16_RS15200	COG2203	Gaf domain
ACU16_RS15200	COG5001	Diguanylate cyclase
ACU16_RS15205	COG0629	single-stranded DNA binding
ACU16_RS15210	COG0142	geranyltranstransferase activity
ACU16_RS15235	COG0527	aspartate kinase activity
ACU16_RS15245	COG0384	phenazine biosynthesis protein PhzF
ACU16_RS15255	COG1764	response to oxidative stress
ACU16_RS15265	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACU16_RS15270	COG1678	Uncharacterized ACR, COG1678
ACU16_RS15285	COG0519	Catalyzes the synthesis of GMP from XMP
ACU16_RS15310	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACU16_RS15360	COG1959	2 iron, 2 sulfur cluster binding
ACU16_RS15365	COG0719	Fe-S assembly protein
ACU16_RS15370	COG0396	ATPase activity
ACU16_RS15375	COG0719	Fe-S assembly protein
ACU16_RS15380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACU16_RS15390	COG2146	nitrite reductase [NAD(P)H] activity
ACU16_RS15405	COG1555	photosystem II stabilization
ACU16_RS15410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACU16_RS15425	COG3178	'Phosphotransferase
ACU16_RS15430	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACU16_RS15440	COG0628	permease
ACU16_RS15450	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACU16_RS15465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACU16_RS15485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACU16_RS15490	COG0271	Belongs to the BolA IbaG family
ACU16_RS15500	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACU16_RS15510	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ACU16_RS15515	COG1137	ATPase activity
ACU16_RS15530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACU16_RS15540	COG1660	Displays ATPase and GTPase activities
ACU16_RS15550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACU16_RS15555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACU16_RS15560	COG2239	Acts as a magnesium transporter
ACU16_RS15570	COG1294	oxidase, subunit
ACU16_RS15575	COG1271	oxidase subunit
ACU16_RS15580	COG1113	amino acid transport
ACU16_RS15590	COG2197	response regulator
ACU16_RS15595	COG0531	amino acid
ACU16_RS15680	COG0754	glutathionylspermidine amidase activity
ACU16_RS15705	COG1842	Phage shock protein A
ACU16_RS15720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACU16_RS15745	COG2963	transposase activity
ACU16_RS15750	COG2801	Transposase and inactivated derivatives
ACU16_RS15830	COG3179	chitinase
ACU16_RS15840	COG3179	chitinase
ACU16_RS15855	COG2963	transposase activity
ACU16_RS15900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACU16_RS15915	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACU16_RS16040	COG2963	transposase activity
ACU16_RS16045	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ACU16_RS16070	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ACU16_RS16085	COG2197	response regulator
ACU16_RS16090	COG4585	Histidine kinase
ACU16_RS16105	COG2894	cell division
ACU16_RS16110	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ACU16_RS16120	COG0642	Histidine kinase
ACU16_RS16125	COG0745	RESPONSE REGULATOR receiver
ACU16_RS16130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACU16_RS16140	COG2194	sulfuric ester hydrolase activity
ACU16_RS16175	COG3551	Protein conserved in bacteria
ACU16_RS16185	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACU16_RS16185	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACU16_RS16215	COG0753	catalase activity
ACU16_RS16245	COG2801	Transposase and inactivated derivatives
ACU16_RS16275	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS16300	COG2963	transposase activity
ACU16_RS16310	COG0542	response to heat
ACU16_RS16335	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ACU16_RS16355	COG0336	Belongs to the RNA methyltransferase TrmD family
ACU16_RS16360	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACU16_RS16365	COG0228	four-way junction DNA binding
ACU16_RS16375	COG2070	2-Nitropropane dioxygenase
ACU16_RS16390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACU16_RS16395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACU16_RS16435	COG2172	sigma factor antagonist activity
ACU16_RS16440	COG1366	Belongs to the anti-sigma-factor antagonist family
ACU16_RS16445	COG1366	Belongs to the anti-sigma-factor antagonist family
ACU16_RS16460	COG0326	Molecular chaperone. Has ATPase activity
ACU16_RS16465	COG2207	Transcriptional regulator
ACU16_RS16475	COG3152	Membrane
ACU16_RS16490	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS16505	COG2801	Transposase and inactivated derivatives
ACU16_RS16515	COG3209	COG3209 Rhs family protein
ACU16_RS16535	COG3209	COG3209 Rhs family protein
ACU16_RS16550	COG3209	COG3209 Rhs family protein
ACU16_RS16570	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ACU16_RS16575	COG1845	cytochrome c oxidase, subunit III
ACU16_RS16580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACU16_RS16595	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACU16_RS16600	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACU16_RS16610	COG0196	riboflavin kinase activity
ACU16_RS16615	COG0728	peptidoglycan biosynthetic process
ACU16_RS16620	COG0268	Binds directly to 16S ribosomal RNA
ACU16_RS16625	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACU16_RS16630	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ACU16_RS16640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACU16_RS16645	COG0824	Thioesterase
ACU16_RS16660	COG1946	Acyl-CoA thioesterase
ACU16_RS16685	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ACU16_RS16720	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS16730	COG1877	trehalose-phosphatase activity
ACU16_RS16735	COG3387	PFAM Glycoside hydrolase 15-related
ACU16_RS16750	COG0840	transmembrane signaling receptor activity
ACU16_RS16755	COG3011	Protein conserved in bacteria
ACU16_RS16770	COG0564	pseudouridine synthase activity
ACU16_RS16775	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU16_RS16780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACU16_RS16780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACU16_RS16790	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ACU16_RS16795	COG0045	succinate-CoA ligase (ADP-forming) activity
ACU16_RS16810	COG2184	nucleotidyltransferase activity
ACU16_RS16830	COG2194	sulfuric ester hydrolase activity
ACU16_RS16835	COG4969	Belongs to the N-Me-Phe pilin family
ACU16_RS16845	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ACU16_RS16855	COG3039	Transposase
ACU16_RS16870	COG2801	Transposase and inactivated derivatives
ACU16_RS16885	COG2801	Transposase and inactivated derivatives
ACU16_RS16905	COG0745	RESPONSE REGULATOR receiver
ACU16_RS16975	COG2833	Protein of unknown function (DUF455)
ACU16_RS16995	COG0285	dihydrofolate synthase activity
ACU16_RS17000	COG0406	alpha-ribazole phosphatase activity
ACU16_RS17030	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACU16_RS17035	COG4208	sulfate ABC transporter
ACU16_RS17040	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACU16_RS17045	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACU16_RS17050	COG0156	8-amino-7-oxononanoate synthase activity
ACU16_RS17075	COG0604	alcohol dehydrogenase
ACU16_RS17080	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACU16_RS17080	COG1902	pentaerythritol trinitrate reductase activity
ACU16_RS17115	COG0584	glycerophosphoryl diester phosphodiesterase
ACU16_RS17145	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACU16_RS17150	COG1217	gtp-binding protein TYPA
ACU16_RS17170	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ACU16_RS17180	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ACU16_RS17185	COG0203	ribosomal protein L17
ACU16_RS17195	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACU16_RS17200	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACU16_RS17210	COG0201	protein transport
ACU16_RS17215	COG0200	Binds to the 23S rRNA
ACU16_RS17220	COG1841	ribosomal large subunit assembly
ACU16_RS17250	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACU16_RS17255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACU16_RS17260	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACU16_RS17265	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACU16_RS17270	COG0255	Belongs to the universal ribosomal protein uL29 family
ACU16_RS17275	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACU16_RS17295	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACU16_RS17300	COG0089	rRNA binding
ACU16_RS17305	COG0088	Forms part of the polypeptide exit tunnel
ACU16_RS17315	COG0051	transcription antitermination factor activity, RNA binding
ACU16_RS17335	COG0049	tRNA binding
ACU16_RS17340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACU16_RS17345	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACU16_RS17350	COG0085	RNA polymerase activity
ACU16_RS17360	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACU16_RS17365	COG0081	regulation of translation
ACU16_RS17370	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACU16_RS17375	COG0250	Participates in transcription elongation, termination and antitermination
ACU16_RS17410	COG0012	GTP binding
ACU16_RS17415	COG0193	aminoacyl-tRNA hydrolase activity
ACU16_RS17425	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACU16_RS17440	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ACU16_RS17450	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACU16_RS17455	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACU16_RS17465	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACU16_RS17485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACU16_RS17490	COG1295	ribonuclease BN
ACU16_RS17515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACU16_RS17525	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACU16_RS17565	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACU16_RS17610	COG2890	protein-(glutamine-N5) methyltransferase activity
ACU16_RS17620	COG3634	alkyl hydroperoxide reductase activity
ACU16_RS17625	COG0583	DNA-binding transcription factor activity
ACU16_RS17635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACU16_RS17640	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACU16_RS17650	COG2197	response regulator
ACU16_RS17670	COG3039	Transposase
ACU16_RS17690	COG0697	spore germination
ACU16_RS17715	COG3386	PFAM SMP-30 Gluconolaconase
ACU16_RS17735	COG1024	Enoyl-CoA hydratase
ACU16_RS17745	COG0318	PFAM AMP-dependent synthetase and ligase
ACU16_RS17750	COG0583	DNA-binding transcription factor activity
ACU16_RS17755	COG3384	dioxygenase
ACU16_RS17785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACU16_RS17790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACU16_RS17800	COG2096	Adenosyltransferase
ACU16_RS17805	COG0123	including yeast histone deacetylase and acetoin utilization protein
ACU16_RS17820	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACU16_RS17825	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACU16_RS17830	COG2967	ApaG domain
ACU16_RS17835	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACU16_RS17855	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACU16_RS17875	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACU16_RS17885	COG0642	Histidine kinase
ACU16_RS17900	COG4181	ATPase activity
ACU16_RS17915	COG2175	clavaminate synthase activity
ACU16_RS17950	COG0667	Aldo Keto reductase
ACU16_RS17960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACU16_RS17965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU16_RS17980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACU16_RS17995	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACU16_RS18030	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACU16_RS18035	COG2226	methyltransferase
ACU16_RS18080	COG3321	synthase
ACU16_RS18080	COG1028	Short-chain dehydrogenase reductase Sdr
ACU16_RS18080	COG0604	alcohol dehydrogenase
ACU16_RS18090	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACU16_RS18100	COG0494	nUDIX hydrolase
ACU16_RS18115	COG4942	peptidase
ACU16_RS18115	COG1388	LysM domain
ACU16_RS18125	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ACU16_RS18140	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACU16_RS18145	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACU16_RS18150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACU16_RS18165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACU16_RS18170	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACU16_RS18185	COG3116	cell division
ACU16_RS18190	COG0275	rRNA processing
ACU16_RS18225	COG0792	nuclease activity
ACU16_RS18230	COG1988	membrane-bound metal-dependent
ACU16_RS18235	COG0277	FAD linked oxidase domain protein
ACU16_RS18240	COG0745	RESPONSE REGULATOR receiver
ACU16_RS18245	COG2205	protein histidine kinase activity
ACU16_RS18255	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ACU16_RS18260	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACU16_RS18280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACU16_RS18285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACU16_RS18290	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACU16_RS18310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU16_RS18310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU16_RS18315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU16_RS18315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU16_RS18325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACU16_RS18335	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACU16_RS18355	COG0488	(ABC) transporter
ACU16_RS18380	COG3791	Glutathione-dependent formaldehyde-activating
ACU16_RS18385	COG3791	Glutathione-dependent formaldehyde-activating
ACU16_RS18410	COG2205	protein histidine kinase activity
ACU16_RS18435	COG2205	protein histidine kinase activity
ACU16_RS18450	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ACU16_RS18475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACU16_RS18490	COG1012	belongs to the aldehyde dehydrogenase family
ACU16_RS18520	COG1649	PFAM Uncharacterised BCR, COG1649
ACU16_RS18520	COG0726	polysaccharide deacetylase
ACU16_RS18525	COG1215	transferase activity, transferring glycosyl groups
ACU16_RS18535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACU16_RS18540	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACU16_RS18545	COG1609	Transcriptional regulator
ACU16_RS18555	COG2188	Transcriptional regulator
ACU16_RS18570	COG3250	beta-galactosidase activity
ACU16_RS18590	COG2801	Transposase and inactivated derivatives
ACU16_RS18605	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACU16_RS18610	COG4191	Histidine kinase
ACU16_RS18615	COG0784	Response regulator, receiver
ACU16_RS18620	COG4251	negative regulation of phosphorylation
ACU16_RS18625	COG2823	Periplasmic or secreted lipoprotein
ACU16_RS18630	COG0673	inositol 2-dehydrogenase activity
ACU16_RS18635	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ACU16_RS18675	COG1056	cytidyltransferase-related domain
ACU16_RS18675	COG1051	belongs to the nudix hydrolase family
ACU16_RS18700	COG2921	Belongs to the UPF0250 family
ACU16_RS18710	COG1686	Belongs to the peptidase S11 family
ACU16_RS18720	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACU16_RS18725	COG2951	lytic endotransglycosylase activity
ACU16_RS18745	COG2801	Transposase and inactivated derivatives
ACU16_RS18755	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS18775	COG3210	domain, Protein
ACU16_RS18780	COG2831	hemolysin activation secretion protein
ACU16_RS18810	COG3039	Transposase
ACU16_RS18815	COG2951	lytic endotransglycosylase activity
ACU16_RS18825	COG2801	Transposase and inactivated derivatives
ACU16_RS18830	COG1136	(ABC) transporter
ACU16_RS18830	COG0577	efflux transmembrane transporter activity
ACU16_RS18875	COG3039	Transposase
ACU16_RS18900	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACU16_RS18910	COG0842	Transport permease protein
ACU16_RS18915	COG1131	(ABC) transporter
ACU16_RS18920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACU16_RS18940	COG1476	TRANSCRIPTIONal
ACU16_RS18950	COG4555	ABC transporter
ACU16_RS18985	COG0625	glutathione transferase activity
ACU16_RS19020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACU16_RS19030	COG1560	Kdo2-lipid A biosynthetic process
ACU16_RS19075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACU16_RS19075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACU16_RS19080	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACU16_RS19085	COG0242	peptide deformylase activity
ACU16_RS19090	COG1652	LysM domain
ACU16_RS19095	COG0758	DNA mediated transformation
ACU16_RS19115	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACU16_RS19115	COG1754	DNA topoisomerase type I activity
ACU16_RS19120	COG0009	L-threonylcarbamoyladenylate synthase
ACU16_RS19135	COG1028	Short-chain dehydrogenase reductase Sdr
ACU16_RS19145	COG0616	signal peptide processing
ACU16_RS19150	COG0534	Mate efflux family protein
ACU16_RS19170	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACU16_RS19175	COG1324	tolerance protein
ACU16_RS19190	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ACU16_RS19195	COG0511	ligase activity, forming carbon-carbon bonds
ACU16_RS19205	COG0439	Biotin carboxylase
ACU16_RS19245	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ACU16_RS19255	COG3293	Transposase
ACU16_RS19275	COG0138	bifunctional purine biosynthesis protein purh
ACU16_RS19280	COG0151	Belongs to the GarS family
ACU16_RS19285	COG1136	(ABC) transporter
ACU16_RS19285	COG0577	efflux transmembrane transporter activity
ACU16_RS19300	COG1289	transmembrane transporter activity
ACU16_RS19315	COG2814	Major facilitator Superfamily
ACU16_RS19325	COG2814	Major facilitator Superfamily
ACU16_RS19340	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ACU16_RS19410	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACU16_RS19420	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ACU16_RS19430	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ACU16_RS19435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACU16_RS19445	COG0134	indole-3-glycerol-phosphate synthase activity
ACU16_RS19450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACU16_RS19490	COG0456	acetyltransferase
ACU16_RS19500	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ACU16_RS19550	COG2801	Transposase and inactivated derivatives
ACU16_RS19670	COG0740	serine-type endopeptidase activity
ACU16_RS19680	COG1802	Transcriptional regulator
ACU16_RS19680	COG4626	Terminase
ACU16_RS19775	COG0582	viral genome integration into host DNA
ACU16_RS19790	COG1192	Involved in chromosome partitioning
ACU16_RS19795	COG1475	DNA binding
ACU16_RS19810	COG0463	Glycosyl transferase, family 2
ACU16_RS19835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACU16_RS19860	COG4221	oxidoreductase activity
ACU16_RS19865	COG2755	lipolytic protein G-D-S-L family
ACU16_RS19865	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACU16_RS19880	COG1166	arginine decarboxylase activity
ACU16_RS19885	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ACU16_RS19920	COG3501	Rhs element vgr protein
ACU16_RS19920	COG3409	Peptidoglycan-binding domain 1 protein
ACU16_RS19950	COG0084	hydrolase, TatD family'
ACU16_RS19965	COG2814	Major facilitator Superfamily
ACU16_RS19975	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACU16_RS19980	COG1902	pentaerythritol trinitrate reductase activity
ACU16_RS20005	COG2205	protein histidine kinase activity
ACU16_RS20010	COG2205	protein histidine kinase activity
ACU16_RS20020	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACU16_RS20025	COG0583	DNA-binding transcription factor activity
ACU16_RS20050	COG1733	regulation of RNA biosynthetic process
ACU16_RS20055	COG0702	epimerase
ACU16_RS20090	COG0583	DNA-binding transcription factor activity
ACU16_RS20125	COG1199	ATP-dependent helicase activity
ACU16_RS20155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACU16_RS20185	COG3228	Belongs to the MtfA family
ACU16_RS20195	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ACU16_RS20195	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ACU16_RS20200	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ACU16_RS20215	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACU16_RS20255	COG3237	CsbD-like
ACU16_RS20260	COG0180	Tryptophanyl-tRNA synthetase
ACU16_RS20265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACU16_RS20280	COG3039	Transposase
ACU16_RS20310	COG0753	catalase activity
ACU16_RS20325	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACU16_RS20360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACU16_RS20370	COG0642	Histidine kinase
ACU16_RS20375	COG1090	epimerase
ACU16_RS20425	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ACU16_RS20435	COG0606	chelatase, subunit chli
ACU16_RS20490	COG2963	transposase activity
ACU16_RS20495	COG2801	Transposase and inactivated derivatives
ACU16_RS20520	COG2963	transposase activity
ACU16_RS20535	COG3409	Peptidoglycan-binding domain 1 protein
ACU16_RS20535	COG3501	Rhs element vgr protein
ACU16_RS20545	COG3039	Transposase
ACU16_RS20555	COG2801	Transposase and inactivated derivatives
ACU16_RS20565	COG3039	Transposase
ACU16_RS20575	COG3039	Transposase
ACU16_RS20585	COG3039	Transposase
ACU16_RS20605	COG0702	epimerase
ACU16_RS20630	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACU16_RS20650	COG1649	PFAM Uncharacterised BCR, COG1649
ACU16_RS20655	COG2354	Protein conserved in bacteria
ACU16_RS20660	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACU16_RS20665	COG3039	Transposase
ACU16_RS20680	COG1511	domain protein
ACU16_RS20680	COG3264	Mechanosensitive ion channel
ACU16_RS20755	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACU16_RS20840	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS20850	COG0246	Mannitol dehydrogenase
ACU16_RS20855	COG1472	Belongs to the glycosyl hydrolase 3 family
ACU16_RS20865	COG4948	Mandelate Racemase Muconate Lactonizing
ACU16_RS20875	COG3661	Belongs to the glycosyl hydrolase 67 family
ACU16_RS20895	COG2974	May be involved in recombination
ACU16_RS20915	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACU16_RS20925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACU16_RS20930	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACU16_RS20935	COG0805	protein transport
ACU16_RS20945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACU16_RS20945	COG0519	Catalyzes the synthesis of GMP from XMP
ACU16_RS20955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACU16_RS20960	COG0752	glycyl-tRNA synthetase alpha subunit
ACU16_RS20970	COG0457	Tetratricopeptide repeat
ACU16_RS20975	COG4771	TonB-dependent receptor
ACU16_RS21015	COG3039	Transposase
ACU16_RS21020	COG2963	transposase activity
ACU16_RS21025	COG2801	Transposase and inactivated derivatives
ACU16_RS21050	COG0729	surface antigen
ACU16_RS21055	COG2911	Protein conserved in bacteria
ACU16_RS21090	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS21150	COG0582	viral genome integration into host DNA
ACU16_RS21160	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACU16_RS21165	COG1040	competence protein
ACU16_RS21170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACU16_RS21175	COG0156	8-amino-7-oxononanoate synthase activity
ACU16_RS21215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACU16_RS21255	COG2963	transposase activity
ACU16_RS21270	COG2801	Transposase and inactivated derivatives
ACU16_RS21290	COG0657	acetylesterase activity
ACU16_RS21300	COG1414	Transcriptional regulator
ACU16_RS21310	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACU16_RS21315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACU16_RS21325	COG3485	protocatechuate 3,4-dioxygenase
ACU16_RS21330	COG3485	protocatechuate 3,4-dioxygenase
ACU16_RS21340	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACU16_RS21345	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACU16_RS21415	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ACU16_RS21425	COG0129	dihydroxy-acid dehydratase activity
ACU16_RS21430	COG2826	transposase and inactivated derivatives, IS30 family
ACU16_RS21455	COG2211	Major facilitator Superfamily
ACU16_RS21475	COG3693	PFAM glycoside hydrolase, family 10
ACU16_RS21480	COG3693	PFAM glycoside hydrolase, family 10
ACU16_RS21510	COG4770	biotin carboxylase activity
ACU16_RS21515	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACU16_RS21520	COG1960	acyl-CoA dehydrogenase activity
ACU16_RS21565	COG0523	cobalamin synthesis protein
ACU16_RS21585	COG0697	spore germination
ACU16_RS21595	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ACU16_RS21600	COG1846	Transcriptional regulator
ACU16_RS21605	COG1764	response to oxidative stress
ACU16_RS21625	COG3293	Transposase
ACU16_RS21640	COG0656	L-ascorbic acid biosynthetic process
ACU16_RS21645	COG2130	NADP-dependent
ACU16_RS21650	COG0667	Aldo Keto reductase
ACU16_RS21660	COG1187	pseudouridine synthase activity
ACU16_RS21670	COG1643	Atp-dependent helicase
ACU16_RS21680	COG4807	Protein conserved in bacteria
ACU16_RS21700	COG3039	Transposase
ACU16_RS21710	COG2124	cytochrome p450
ACU16_RS21715	COG2124	cytochrome p450
ACU16_RS21720	COG1141	Ferredoxin
ACU16_RS21725	COG1028	Short-chain dehydrogenase reductase Sdr
ACU16_RS21730	COG2124	cytochrome p450
ACU16_RS21735	COG0142	geranyltranstransferase activity
ACU16_RS21740	COG1657	PFAM Prenyltransferase squalene oxidase
ACU16_RS21750	COG1304	FMN binding
ACU16_RS21765	COG0564	pseudouridine synthase activity
ACU16_RS21790	COG3706	GGDEF domain
ACU16_RS21800	COG1929	Belongs to the glycerate kinase type-1 family
ACU16_RS21805	COG2271	Major facilitator Superfamily
ACU16_RS21820	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACU16_RS21825	COG0861	Integral membrane protein TerC family
ACU16_RS21835	COG0584	glycerophosphoryl diester phosphodiesterase
ACU16_RS21845	COG0671	phosphoesterase, PA-phosphatase related
ACU16_RS21865	COG2963	transposase activity
ACU16_RS21870	COG2801	Transposase and inactivated derivatives
ACU16_RS21890	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACU16_RS21915	COG0582	viral genome integration into host DNA
ACU16_RS21920	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACU16_RS21925	COG0726	polysaccharide deacetylase