locus-tag	class	description
ACU12_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACU12_RS00020	COG0187	DNA topoisomerase II activity
ACU12_RS00030	COG0501	Belongs to the peptidase M48B family
ACU12_RS00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACU12_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU12_RS00075	COG3039	Transposase
ACU12_RS00090	COG1064	alcohol dehydrogenase
ACU12_RS00095	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU12_RS00100	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU12_RS00105	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU12_RS00115	COG2234	aminopeptidase activity
ACU12_RS00125	COG4942	peptidase
ACU12_RS00130	COG0793	Belongs to the peptidase S41A family
ACU12_RS00135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACU12_RS00175	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACU12_RS00200	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ACU12_RS00215	COG0210	DNA helicase
ACU12_RS00235	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ACU12_RS00240	COG0284	orotidine-5'-phosphate decarboxylase activity
ACU12_RS00270	COG2937	Belongs to the GPAT DAPAT family
ACU12_RS00275	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_RS00275	COG0604	alcohol dehydrogenase
ACU12_RS00275	COG3321	synthase
ACU12_RS00305	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACU12_RS00330	COG2351	hydroxyisourate hydrolase activity
ACU12_RS00335	COG4807	Protein conserved in bacteria
ACU12_RS00345	COG1643	Atp-dependent helicase
ACU12_RS00355	COG1187	pseudouridine synthase activity
ACU12_RS00365	COG0667	Aldo Keto reductase
ACU12_RS00370	COG2130	NADP-dependent
ACU12_RS00375	COG0656	L-ascorbic acid biosynthetic process
ACU12_RS00390	COG3293	Transposase
ACU12_RS00410	COG1764	response to oxidative stress
ACU12_RS00415	COG1846	Transcriptional regulator
ACU12_RS00420	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ACU12_RS00430	COG0697	spore germination
ACU12_RS00440	COG0523	cobalamin synthesis protein
ACU12_RS00485	COG1960	acyl-CoA dehydrogenase activity
ACU12_RS00490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACU12_RS00495	COG4770	biotin carboxylase activity
ACU12_RS00530	COG3693	PFAM glycoside hydrolase, family 10
ACU12_RS00535	COG3693	PFAM glycoside hydrolase, family 10
ACU12_RS00555	COG2211	Major facilitator Superfamily
ACU12_RS00585	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_RS00590	COG0129	dihydroxy-acid dehydratase activity
ACU12_RS00600	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ACU12_RS00670	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACU12_RS00675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACU12_RS00685	COG3485	protocatechuate 3,4-dioxygenase
ACU12_RS00690	COG3485	protocatechuate 3,4-dioxygenase
ACU12_RS00700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACU12_RS00705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACU12_RS00715	COG1414	Transcriptional regulator
ACU12_RS00725	COG0657	acetylesterase activity
ACU12_RS00795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACU12_RS00835	COG0156	8-amino-7-oxononanoate synthase activity
ACU12_RS00840	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACU12_RS00845	COG1040	competence protein
ACU12_RS00850	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACU12_RS00875	COG2911	Protein conserved in bacteria
ACU12_RS00880	COG0729	surface antigen
ACU12_RS00895	COG0457	Tetratricopeptide repeat
ACU12_RS00905	COG0752	glycyl-tRNA synthetase alpha subunit
ACU12_RS00910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACU12_RS00920	COG0519	Catalyzes the synthesis of GMP from XMP
ACU12_RS00920	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACU12_RS00930	COG0805	protein transport
ACU12_RS00935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACU12_RS00940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACU12_RS00950	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACU12_RS00970	COG2974	May be involved in recombination
ACU12_RS00990	COG3661	Belongs to the glycosyl hydrolase 67 family
ACU12_RS01000	COG4948	Mandelate Racemase Muconate Lactonizing
ACU12_RS01010	COG1472	Belongs to the glycosyl hydrolase 3 family
ACU12_RS01015	COG0246	Mannitol dehydrogenase
ACU12_RS01115	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACU12_RS01185	COG1511	domain protein
ACU12_RS01185	COG3264	Mechanosensitive ion channel
ACU12_RS01200	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACU12_RS01205	COG2354	Protein conserved in bacteria
ACU12_RS01210	COG1649	PFAM Uncharacterised BCR, COG1649
ACU12_RS01230	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACU12_RS01255	COG0702	epimerase
ACU12_RS01265	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_RS01275	COG3039	Transposase
ACU12_RS01315	COG2801	Transposase and inactivated derivatives
ACU12_RS01360	COG2801	Transposase and inactivated derivatives
ACU12_RS01365	COG2963	transposase activity
ACU12_RS01405	COG0084	hydrolase, TatD family'
ACU12_RS01415	COG0583	DNA-binding transcription factor activity
ACU12_RS01420	COG2814	Major facilitator Superfamily
ACU12_RS01430	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACU12_RS01435	COG1902	pentaerythritol trinitrate reductase activity
ACU12_RS01455	COG0745	RESPONSE REGULATOR receiver
ACU12_RS01460	COG2205	protein histidine kinase activity
ACU12_RS01465	COG2205	protein histidine kinase activity
ACU12_RS01475	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACU12_RS01480	COG0583	DNA-binding transcription factor activity
ACU12_RS01505	COG1733	regulation of RNA biosynthetic process
ACU12_RS01510	COG0702	epimerase
ACU12_RS01580	COG1199	ATP-dependent helicase activity
ACU12_RS01620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACU12_RS01650	COG3228	Belongs to the MtfA family
ACU12_RS01665	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ACU12_RS01680	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACU12_RS01710	COG3237	CsbD-like
ACU12_RS01715	COG0180	Tryptophanyl-tRNA synthetase
ACU12_RS01720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACU12_RS01760	COG0753	catalase activity
ACU12_RS01775	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACU12_RS01805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACU12_RS01815	COG0642	Histidine kinase
ACU12_RS01820	COG1090	epimerase
ACU12_RS01865	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ACU12_RS01875	COG0606	chelatase, subunit chli
ACU12_RS01930	COG2963	transposase activity
ACU12_RS01955	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ACU12_RS01960	COG1166	arginine decarboxylase activity
ACU12_RS01975	COG2755	lipolytic protein G-D-S-L family
ACU12_RS01975	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACU12_RS01980	COG4221	oxidoreductase activity
ACU12_RS02005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACU12_RS02030	COG0463	Glycosyl transferase, family 2
ACU12_RS02045	COG1475	DNA binding
ACU12_RS02050	COG1192	Involved in chromosome partitioning
ACU12_RS02075	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ACU12_RS02085	COG0456	acetyltransferase
ACU12_RS02125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACU12_RS02130	COG0134	indole-3-glycerol-phosphate synthase activity
ACU12_RS02140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACU12_RS02145	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ACU12_RS02155	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ACU12_RS02165	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACU12_RS02235	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ACU12_RS02250	COG2814	Major facilitator Superfamily
ACU12_RS02265	COG1289	transmembrane transporter activity
ACU12_RS02275	COG1136	(ABC) transporter
ACU12_RS02275	COG0577	efflux transmembrane transporter activity
ACU12_RS02280	COG0151	Belongs to the GarS family
ACU12_RS02285	COG0138	bifunctional purine biosynthesis protein purh
ACU12_RS02300	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ACU12_RS02335	COG0439	Biotin carboxylase
ACU12_RS02345	COG0511	ligase activity, forming carbon-carbon bonds
ACU12_RS02350	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ACU12_RS02365	COG1324	tolerance protein
ACU12_RS02370	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACU12_RS02390	COG0534	Mate efflux family protein
ACU12_RS02395	COG0616	signal peptide processing
ACU12_RS02405	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_RS02420	COG0009	L-threonylcarbamoyladenylate synthase
ACU12_RS02425	COG1754	DNA topoisomerase type I activity
ACU12_RS02425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACU12_RS02445	COG0758	DNA mediated transformation
ACU12_RS02450	COG1652	LysM domain
ACU12_RS02455	COG0242	peptide deformylase activity
ACU12_RS02460	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACU12_RS02465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACU12_RS02465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACU12_RS02510	COG1560	Kdo2-lipid A biosynthetic process
ACU12_RS02520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACU12_RS02550	COG0625	glutathione transferase activity
ACU12_RS02585	COG4555	ABC transporter
ACU12_RS02595	COG1476	TRANSCRIPTIONal
ACU12_RS02615	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACU12_RS02620	COG1131	(ABC) transporter
ACU12_RS02625	COG0842	Transport permease protein
ACU12_RS02635	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACU12_RS02660	COG3039	Transposase
ACU12_RS02700	COG0577	efflux transmembrane transporter activity
ACU12_RS02715	COG2963	transposase activity
ACU12_RS02720	COG2951	lytic endotransglycosylase activity
ACU12_RS02750	COG3039	Transposase
ACU12_RS02765	COG3209	COG3209 Rhs family protein
ACU12_RS02775	COG2801	Transposase and inactivated derivatives
ACU12_RS02790	COG2831	hemolysin activation secretion protein
ACU12_RS02795	COG3210	domain, Protein
ACU12_RS02795	COG3210	domain, Protein
ACU12_RS02815	COG3210	domain, Protein
ACU12_RS02825	COG3039	Transposase
ACU12_RS02865	COG2963	transposase activity
ACU12_RS02880	COG4221	oxidoreductase activity
ACU12_RS02925	COG0697	spore germination
ACU12_RS02930	COG4305	rare lipoprotein A
ACU12_RS02955	COG1113	amino acid transport
ACU12_RS02965	COG0598	Magnesium transport protein CorA
ACU12_RS03035	COG0659	secondary active sulfate transmembrane transporter activity
ACU12_RS03060	COG3275	phosphorelay sensor kinase activity
ACU12_RS03070	COG0181	hydroxymethylbilane synthase activity
ACU12_RS03095	COG1505	serine-type exopeptidase activity
ACU12_RS03105	COG0436	Aminotransferase
ACU12_RS03115	COG2832	Protein of unknown function (DUF454)
ACU12_RS03135	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ACU12_RS03180	COG5001	Diguanylate cyclase
ACU12_RS03180	COG3300	MHYT domain
ACU12_RS03200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU12_RS03205	COG1077	Cell shape determining protein MreB Mrl
ACU12_RS03210	COG1792	Involved in formation and maintenance of cell shape
ACU12_RS03225	COG0772	Belongs to the SEDS family
ACU12_RS03245	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_RS03265	COG2951	lytic endotransglycosylase activity
ACU12_RS03270	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACU12_RS03280	COG1686	Belongs to the peptidase S11 family
ACU12_RS03290	COG2921	Belongs to the UPF0250 family
ACU12_RS03315	COG1056	cytidyltransferase-related domain
ACU12_RS03315	COG1051	belongs to the nudix hydrolase family
ACU12_RS03355	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ACU12_RS03360	COG0673	inositol 2-dehydrogenase activity
ACU12_RS03365	COG2823	Periplasmic or secreted lipoprotein
ACU12_RS03370	COG4251	negative regulation of phosphorylation
ACU12_RS03375	COG0784	Response regulator, receiver
ACU12_RS03380	COG4191	Histidine kinase
ACU12_RS03385	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACU12_RS03400	COG2801	Transposase and inactivated derivatives
ACU12_RS03415	COG3250	beta-galactosidase activity
ACU12_RS03430	COG2188	Transcriptional regulator
ACU12_RS03440	COG1609	Transcriptional regulator
ACU12_RS03445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACU12_RS03450	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACU12_RS03460	COG1215	transferase activity, transferring glycosyl groups
ACU12_RS03465	COG0726	polysaccharide deacetylase
ACU12_RS03465	COG1649	PFAM Uncharacterised BCR, COG1649
ACU12_RS03475	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_RS03490	COG1012	belongs to the aldehyde dehydrogenase family
ACU12_RS03520	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ACU12_RS03545	COG2205	protein histidine kinase activity
ACU12_RS03560	COG3039	Transposase
ACU12_RS03575	COG2205	protein histidine kinase activity
ACU12_RS03600	COG3791	Glutathione-dependent formaldehyde-activating
ACU12_RS03620	COG0488	(ABC) transporter
ACU12_RS03640	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACU12_RS03650	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACU12_RS03660	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU12_RS03660	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU12_RS03665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU12_RS03665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU12_RS03685	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACU12_RS03690	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACU12_RS03695	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACU12_RS03715	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACU12_RS03720	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ACU12_RS03730	COG2205	protein histidine kinase activity
ACU12_RS03735	COG0745	RESPONSE REGULATOR receiver
ACU12_RS03740	COG0277	FAD linked oxidase domain protein
ACU12_RS03745	COG1988	membrane-bound metal-dependent
ACU12_RS03750	COG0792	nuclease activity
ACU12_RS03785	COG0275	rRNA processing
ACU12_RS03790	COG3116	cell division
ACU12_RS03805	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACU12_RS03810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACU12_RS03825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACU12_RS03830	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACU12_RS03835	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACU12_RS03850	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ACU12_RS03860	COG4942	peptidase
ACU12_RS03860	COG1388	LysM domain
ACU12_RS03875	COG0494	nUDIX hydrolase
ACU12_RS03885	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACU12_RS03895	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_RS03895	COG3321	synthase
ACU12_RS03895	COG0604	alcohol dehydrogenase
ACU12_RS03945	COG2226	methyltransferase
ACU12_RS03950	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACU12_RS03990	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACU12_RS04005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACU12_RS04020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU12_RS04025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACU12_RS04040	COG0667	Aldo Keto reductase
ACU12_RS04075	COG2175	clavaminate synthase activity
ACU12_RS04085	COG4181	ATPase activity
ACU12_RS04100	COG0642	Histidine kinase
ACU12_RS04110	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACU12_RS04130	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACU12_RS04150	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACU12_RS04155	COG2967	ApaG domain
ACU12_RS04160	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACU12_RS04165	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACU12_RS04180	COG0123	including yeast histone deacetylase and acetoin utilization protein
ACU12_RS04185	COG2096	Adenosyltransferase
ACU12_RS04195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACU12_RS04200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACU12_RS04230	COG3384	dioxygenase
ACU12_RS04235	COG0583	DNA-binding transcription factor activity
ACU12_RS04240	COG0318	PFAM AMP-dependent synthetase and ligase
ACU12_RS04250	COG1024	Enoyl-CoA hydratase
ACU12_RS04270	COG3386	PFAM SMP-30 Gluconolaconase
ACU12_RS04295	COG0697	spore germination
ACU12_RS04325	COG2197	response regulator
ACU12_RS04335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACU12_RS04340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACU12_RS04350	COG0583	DNA-binding transcription factor activity
ACU12_RS04355	COG3634	alkyl hydroperoxide reductase activity
ACU12_RS04365	COG2890	protein-(glutamine-N5) methyltransferase activity
ACU12_RS04410	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACU12_RS04460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACU12_RS04465	COG1404	Belongs to the peptidase S8 family
ACU12_RS04470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACU12_RS04500	COG1295	ribonuclease BN
ACU12_RS04505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACU12_RS04525	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACU12_RS04535	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACU12_RS04540	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACU12_RS04550	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ACU12_RS04565	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACU12_RS04575	COG0193	aminoacyl-tRNA hydrolase activity
ACU12_RS04580	COG0012	GTP binding
ACU12_RS04610	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACU12_RS04615	COG0250	Participates in transcription elongation, termination and antitermination
ACU12_RS04620	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACU12_RS04625	COG0081	regulation of translation
ACU12_RS04630	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACU12_RS04640	COG0085	RNA polymerase activity
ACU12_RS04645	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACU12_RS04650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACU12_RS04655	COG0049	tRNA binding
ACU12_RS04675	COG0051	transcription antitermination factor activity, RNA binding
ACU12_RS04685	COG0088	Forms part of the polypeptide exit tunnel
ACU12_RS04690	COG0089	rRNA binding
ACU12_RS04695	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACU12_RS04715	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACU12_RS04720	COG0255	Belongs to the universal ribosomal protein uL29 family
ACU12_RS04725	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACU12_RS04730	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACU12_RS04735	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACU12_RS04740	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACU12_RS04770	COG1841	ribosomal large subunit assembly
ACU12_RS04775	COG0200	Binds to the 23S rRNA
ACU12_RS04780	COG0201	protein transport
ACU12_RS04790	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACU12_RS04795	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACU12_RS04805	COG0203	ribosomal protein L17
ACU12_RS04810	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ACU12_RS04820	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ACU12_RS04840	COG1217	gtp-binding protein TYPA
ACU12_RS04845	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACU12_RS04875	COG0584	glycerophosphoryl diester phosphodiesterase
ACU12_RS04895	COG1902	pentaerythritol trinitrate reductase activity
ACU12_RS04895	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACU12_RS04900	COG0604	alcohol dehydrogenase
ACU12_RS04925	COG0156	8-amino-7-oxononanoate synthase activity
ACU12_RS04930	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACU12_RS04935	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACU12_RS04940	COG4208	sulfate ABC transporter
ACU12_RS04945	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACU12_RS04980	COG0406	alpha-ribazole phosphatase activity
ACU12_RS04985	COG0285	dihydrofolate synthase activity
ACU12_RS05005	COG2833	Protein of unknown function (DUF455)
ACU12_RS05015	COG3291	Pkd domain containing protein
ACU12_RS05025	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACU12_RS05030	COG0671	phosphoesterase, PA-phosphatase related
ACU12_RS05035	COG0438	transferase activity, transferring glycosyl groups
ACU12_RS05045	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ACU12_RS05060	COG4783	chaperone-mediated protein folding
ACU12_RS05075	COG0473	3-isopropylmalate dehydrogenase activity
ACU12_RS05110	COG2963	transposase activity
ACU12_RS05125	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACU12_RS05165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACU12_RS05190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACU12_RS05195	COG0631	protein serine/threonine phosphatase activity
ACU12_RS05210	COG0859	PFAM glycosyl transferase family 9
ACU12_RS05215	COG3642	lipopolysaccharide core region biosynthetic process
ACU12_RS05220	COG1234	tRNA 3'-trailer cleavage
ACU12_RS05225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACU12_RS05235	COG0315	cyclic pyranopterin monophosphate synthase activity
ACU12_RS05240	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ACU12_RS05245	COG0314	molybdopterin synthase activity
ACU12_RS05260	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACU12_RS05270	COG0537	adenosine 5'-monophosphoramidase activity
ACU12_RS05290	COG0714	Associated with various cellular activities
ACU12_RS05310	COG1399	metal-binding, possibly nucleic acid-binding protein
ACU12_RS05335	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_RS05340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACU12_RS05350	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACU12_RS05355	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACU12_RS05385	COG3829	transcription factor binding
ACU12_RS05400	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACU12_RS05445	COG0678	peroxiredoxin activity
ACU12_RS05465	COG0330	HflC and HflK could
ACU12_RS05470	COG0330	HflC and HflK could
ACU12_RS05485	COG0308	aminopeptidase N
ACU12_RS05495	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_RS05550	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ACU12_RS05585	COG0732	type I restriction modification DNA specificity domain
ACU12_RS05660	COG0587	DNA-directed DNA polymerase activity
ACU12_RS05675	COG1297	OPT oligopeptide transporter protein
ACU12_RS05685	COG1506	peptidase
ACU12_RS05685	COG0823	Involved in the tonB-independent uptake of proteins
ACU12_RS05695	COG1917	Cupin 2, conserved barrel domain protein
ACU12_RS05695	COG2207	Transcriptional regulator
ACU12_RS05715	COG0753	catalase activity
ACU12_RS05750	COG3551	Protein conserved in bacteria
ACU12_RS05785	COG2194	sulfuric ester hydrolase activity
ACU12_RS05795	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACU12_RS05800	COG0745	RESPONSE REGULATOR receiver
ACU12_RS05805	COG0642	Histidine kinase
ACU12_RS05815	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ACU12_RS05820	COG2894	cell division
ACU12_RS05835	COG4585	Histidine kinase
ACU12_RS05840	COG2197	response regulator
ACU12_RS05855	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ACU12_RS05885	COG2963	transposase activity
ACU12_RS06000	COG3179	chitinase
ACU12_RS06010	COG2801	Transposase and inactivated derivatives
ACU12_RS06015	COG2963	transposase activity
ACU12_RS06145	COG3039	Transposase
ACU12_RS06195	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACU12_RS06210	COG1842	Phage shock protein A
ACU12_RS06235	COG0754	glutathionylspermidine amidase activity
ACU12_RS06305	COG3039	Transposase
ACU12_RS06320	COG0531	amino acid
ACU12_RS06325	COG2197	response regulator
ACU12_RS06335	COG1113	amino acid transport
ACU12_RS06340	COG1271	oxidase subunit
ACU12_RS06345	COG1294	oxidase, subunit
ACU12_RS06355	COG2239	Acts as a magnesium transporter
ACU12_RS06360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACU12_RS06365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACU12_RS06375	COG1660	Displays ATPase and GTPase activities
ACU12_RS06385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACU12_RS06400	COG1137	ATPase activity
ACU12_RS06405	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ACU12_RS06415	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACU12_RS06425	COG0271	Belongs to the BolA IbaG family
ACU12_RS06430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACU12_RS06450	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACU12_RS06465	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACU12_RS06475	COG0628	permease
ACU12_RS06485	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACU12_RS06490	COG3178	'Phosphotransferase
ACU12_RS06510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACU12_RS06515	COG1555	photosystem II stabilization
ACU12_RS06535	COG2146	nitrite reductase [NAD(P)H] activity
ACU12_RS06545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACU12_RS06550	COG0719	Fe-S assembly protein
ACU12_RS06555	COG0396	ATPase activity
ACU12_RS06560	COG0719	Fe-S assembly protein
ACU12_RS06565	COG1959	2 iron, 2 sulfur cluster binding
ACU12_RS06615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACU12_RS06640	COG0519	Catalyzes the synthesis of GMP from XMP
ACU12_RS06655	COG1678	Uncharacterized ACR, COG1678
ACU12_RS06660	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACU12_RS06670	COG1764	response to oxidative stress
ACU12_RS06680	COG0384	phenazine biosynthesis protein PhzF
ACU12_RS06690	COG0527	aspartate kinase activity
ACU12_RS06730	COG0142	geranyltranstransferase activity
ACU12_RS06735	COG0629	single-stranded DNA binding
ACU12_RS06740	COG3706	GGDEF domain
ACU12_RS06740	COG2203	Gaf domain
ACU12_RS06740	COG4251	negative regulation of phosphorylation
ACU12_RS06740	COG5001	Diguanylate cyclase
ACU12_RS06745	COG0604	alcohol dehydrogenase
ACU12_RS06745	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_RS06745	COG3321	synthase
ACU12_RS06755	COG2080	2 iron, 2 sulfur cluster binding
ACU12_RS06760	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACU12_RS06765	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACU12_RS06770	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ACU12_RS06795	COG2879	small protein
ACU12_RS06800	COG1966	Carbon starvation protein
ACU12_RS06805	COG1741	Belongs to the pirin family
ACU12_RS06895	COG1741	Belongs to the pirin family
ACU12_RS06905	COG1515	deoxyribonuclease V activity
ACU12_RS06915	COG2801	Transposase and inactivated derivatives
ACU12_RS06920	COG2963	transposase activity
ACU12_RS06970	COG2801	Transposase and inactivated derivatives
ACU12_RS06995	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACU12_RS07000	COG2199	diguanylate cyclase activity
ACU12_RS07000	COG2200	EAL domain
ACU12_RS07000	COG2202	Pas domain
ACU12_RS07005	COG0835	chemotaxis
ACU12_RS07010	COG0840	transmembrane signaling receptor activity
ACU12_RS07015	COG0643	Histidine kinase
ACU12_RS07015	COG2198	Histidine kinase
ACU12_RS07025	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACU12_RS07035	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACU12_RS07070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACU12_RS07075	COG0735	belongs to the Fur family
ACU12_RS07195	COG5002	protein histidine kinase activity
ACU12_RS07195	COG5001	Diguanylate cyclase
ACU12_RS07200	COG1187	pseudouridine synthase activity
ACU12_RS07215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACU12_RS07225	COG0475	glutathione-regulated potassium exporter activity
ACU12_RS07230	COG5000	phosphorelay sensor kinase activity
ACU12_RS07230	COG5002	protein histidine kinase activity
ACU12_RS07235	COG0745	RESPONSE REGULATOR receiver
ACU12_RS07265	COG1132	(ABC) transporter
ACU12_RS07285	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_RS07325	COG3118	belongs to the thioredoxin family
ACU12_RS07350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACU12_RS07370	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACU12_RS07385	COG2968	Membrane
ACU12_RS07400	COG3164	Protein of unknown function
ACU12_RS07410	COG0312	modulator of DNA gyrase
ACU12_RS07415	COG3028	Belongs to the UPF0307 family
ACU12_RS07420	COG0312	modulator of DNA gyrase
ACU12_RS07445	COG4104	PAAR repeat-containing protein
ACU12_RS07450	COG0142	geranyltranstransferase activity
ACU12_RS07455	COG1722	exodeoxyribonuclease VII activity
ACU12_RS07460	COG0037	tRNA processing
ACU12_RS07465	COG1785	Belongs to the alkaline phosphatase family
ACU12_RS07470	COG1301	dicarboxylic acid transport
ACU12_RS07475	COG4106	trans-aconitate 2-methyltransferase activity
ACU12_RS07490	COG0791	NLP P60 protein
ACU12_RS07495	COG0791	NLP P60 protein
ACU12_RS07500	COG1047	Peptidyl-prolyl cis-trans
ACU12_RS07505	COG2311	Membrane
ACU12_RS07510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU12_RS07530	COG2963	transposase activity
ACU12_RS07535	COG2801	Transposase and inactivated derivatives
ACU12_RS07565	COG2801	Transposase and inactivated derivatives
ACU12_RS07605	COG3590	peptidase
ACU12_RS07620	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACU12_RS07630	COG2914	Belongs to the UPF0125 (RnfH) family
ACU12_RS07635	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU12_RS07645	COG0497	DNA recombination
ACU12_RS07655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACU12_RS07660	COG0443	Heat shock 70 kDa protein
ACU12_RS07665	COG0484	heat shock protein binding
ACU12_RS07670	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ACU12_RS07685	COG0583	DNA-binding transcription factor activity
ACU12_RS07690	COG1132	(ABC) transporter
ACU12_RS07715	COG0567	Dehydrogenase, E1 component
ACU12_RS07725	COG2850	peptidyl-arginine hydroxylation
ACU12_RS07785	COG1131	(ABC) transporter
ACU12_RS07790	COG1725	Transcriptional regulator
ACU12_RS07800	COG0386	Belongs to the glutathione peroxidase family
ACU12_RS07815	COG2900	Belongs to the SlyX family
ACU12_RS07830	COG1609	Transcriptional regulator
ACU12_RS07840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU12_RS07860	COG2226	methyltransferase
ACU12_RS07865	COG1960	acyl-CoA dehydrogenase activity
ACU12_RS07885	COG0557	exoribonuclease II activity
ACU12_RS07895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACU12_RS07905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACU12_RS07915	COG0704	Plays a role in the regulation of phosphate uptake
ACU12_RS07930	COG0573	inorganic phosphate transmembrane transporter activity
ACU12_RS07935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACU12_RS07960	COG0659	secondary active sulfate transmembrane transporter activity
ACU12_RS07965	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACU12_RS07975	COG1024	Enoyl-CoA hydratase
ACU12_RS07985	COG0494	nUDIX hydrolase
ACU12_RS08030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACU12_RS08030	COG0116	Belongs to the methyltransferase superfamily
ACU12_RS08035	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACU12_RS08050	COG0667	Aldo Keto reductase
ACU12_RS08060	COG2925	Exonuclease
ACU12_RS08070	COG3844	kynureninase activity
ACU12_RS08085	COG0288	reversible hydration of carbon dioxide
ACU12_RS08115	COG0316	Belongs to the HesB IscA family
ACU12_RS08120	COG0360	Binds together with S18 to 16S ribosomal RNA
ACU12_RS08140	COG3115	cell septum assembly
ACU12_RS08155	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ACU12_RS08165	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ACU12_RS08210	COG3039	Transposase
ACU12_RS08225	COG0583	DNA-binding transcription factor activity
ACU12_RS08260	COG3039	Transposase
ACU12_RS08270	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_RS08290	COG2801	Transposase and inactivated derivatives
ACU12_RS08300	COG0840	transmembrane signaling receptor activity
ACU12_RS08315	COG3039	Transposase
ACU12_RS08340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACU12_RS08360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACU12_RS08375	COG1595	DNA-templated transcription, initiation
ACU12_RS08425	COG2244	polysaccharide biosynthetic process
ACU12_RS08455	COG2264	protein methyltransferase activity
ACU12_RS08465	COG0438	transferase activity, transferring glycosyl groups
ACU12_RS08480	COG1136	(ABC) transporter
ACU12_RS08485	COG1132	(ABC) transporter
ACU12_RS08490	COG2271	Major facilitator Superfamily
ACU12_RS08495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACU12_RS08510	COG1253	flavin adenine dinucleotide binding
ACU12_RS08545	COG0504	CTP synthase activity
ACU12_RS08550	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ACU12_RS08560	COG0148	phosphopyruvate hydratase activity
ACU12_RS08565	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ACU12_RS08575	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACU12_RS08585	COG2840	Smr protein MutS2
ACU12_RS08590	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACU12_RS08595	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACU12_RS08600	COG1238	metal cluster binding
ACU12_RS08610	COG3737	Protein of unknown function (DUF498/DUF598)
ACU12_RS08615	COG1534	Rna-binding protein
ACU12_RS08620	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ACU12_RS08630	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACU12_RS08645	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACU12_RS08650	COG1546	Belongs to the CinA family
ACU12_RS08665	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACU12_RS08670	COG2137	regulation of response to DNA damage stimulus
ACU12_RS08675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACU12_RS08680	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ACU12_RS08690	COG0305	Participates in initiation and elongation during chromosome replication
ACU12_RS08700	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACU12_RS08720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACU12_RS08750	COG2166	iron-sulfur cluster assembly
ACU12_RS08765	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACU12_RS08770	COG0137	argininosuccinate synthase activity
ACU12_RS08780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACU12_RS08785	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACU12_RS08800	COG0165	Argininosuccinate lyase
ACU12_RS08845	COG1294	oxidase, subunit
ACU12_RS08850	COG1271	oxidase subunit
ACU12_RS08860	COG4988	ABC transporter
ACU12_RS08865	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ACU12_RS08920	COG4133	protoheme IX ABC transporter activity
ACU12_RS08925	COG0436	Aminotransferase
ACU12_RS08945	COG1187	pseudouridine synthase activity
ACU12_RS08950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACU12_RS08955	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACU12_RS08960	COG2350	Protein conserved in bacteria
ACU12_RS08990	COG1175	transmembrane transport
ACU12_RS08995	COG0395	ABC-type sugar transport system, permease component
ACU12_RS09015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACU12_RS09020	COG2957	Belongs to the agmatine deiminase family
ACU12_RS09035	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACU12_RS09040	COG0539	negative regulation of cytoplasmic translation
ACU12_RS09045	COG0776	regulation of translation
ACU12_RS09055	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ACU12_RS09060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACU12_RS09070	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACU12_RS09075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACU12_RS09075	COG0475	glutathione-regulated potassium exporter activity
ACU12_RS09090	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACU12_RS09100	COG0519	Catalyzes the synthesis of GMP from XMP
ACU12_RS09100	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACU12_RS09105	COG3002	Belongs to the UPF0753 family
ACU12_RS09110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACU12_RS09115	COG0583	DNA-binding transcription factor activity
ACU12_RS09135	COG0583	DNA-binding transcription factor activity
ACU12_RS09140	COG0583	DNA-binding transcription factor activity
ACU12_RS09160	COG1914	H( )-stimulated, divalent metal cation uptake system
ACU12_RS09180	COG0668	transmembrane transport
ACU12_RS09205	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_RS09210	COG1183	phosphatidylcholine synthase activity
ACU12_RS09220	COG3243	poly(R)-hydroxyalkanoic acid synthase
ACU12_RS09235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU12_RS09235	COG0723	plastoquinol--plastocyanin reductase activity
ACU12_RS09245	COG2183	response to ionizing radiation
ACU12_RS09250	COG2205	protein histidine kinase activity
ACU12_RS09250	COG0784	Response regulator, receiver
ACU12_RS09360	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_RS09375	COG0800	Aldolase
ACU12_RS09380	COG0129	dihydroxy-acid dehydratase activity
ACU12_RS09385	COG0363	glucosamine-6-phosphate deaminase activity
ACU12_RS09395	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACU12_RS09405	COG0354	folic acid binding
ACU12_RS09415	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ACU12_RS09430	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACU12_RS09445	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACU12_RS09470	COG0811	peptide transport
ACU12_RS09485	COG1663	tetraacyldisaccharide 4'-kinase activity
ACU12_RS09495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACU12_RS09505	COG0322	excinuclease ABC activity
ACU12_RS09530	COG0582	viral genome integration into host DNA
ACU12_RS09555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACU12_RS09570	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACU12_RS09590	COG1054	Belongs to the UPF0176 family
ACU12_RS09600	COG1530	ribonuclease E activity
ACU12_RS09625	COG2154	pterin-4-alpha-carbinolamine dehydratase
ACU12_RS09640	COG2963	transposase activity
ACU12_RS09725	COG3039	Transposase
ACU12_RS09770	COG0631	protein serine/threonine phosphatase activity
ACU12_RS09775	COG0515	serine threonine protein kinase
ACU12_RS09800	COG1858	cytochrome C peroxidase
ACU12_RS09860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU12_RS09865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU12_RS09950	COG3039	Transposase
ACU12_RS09960	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_RS09990	COG2801	Transposase and inactivated derivatives
ACU12_RS10020	COG2801	Transposase and inactivated derivatives
ACU12_RS10025	COG2963	transposase activity
ACU12_RS10030	COG2201	protein-glutamate methylesterase activity
ACU12_RS10045	COG3039	Transposase
ACU12_RS10075	COG4566	intracellular signal transduction
ACU12_RS10090	COG5001	Diguanylate cyclase
ACU12_RS10135	COG1648	precorrin-2 dehydrogenase activity
ACU12_RS10135	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACU12_RS10160	COG0746	molybdenum cofactor guanylyltransferase activity
ACU12_RS10200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACU12_RS10210	COG0303	'Molybdopterin
ACU12_RS10215	COG1160	GTP binding
ACU12_RS10220	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU12_RS10240	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACU12_RS10255	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACU12_RS10255	COG1024	Enoyl-CoA hydratase
ACU12_RS10260	COG0183	Belongs to the thiolase family
ACU12_RS10265	COG0038	chloride channel
ACU12_RS10285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACU12_RS10305	COG1674	ftsk spoiiie
ACU12_RS10310	COG0492	ferredoxin-NADP+ reductase activity
ACU12_RS10340	COG0542	response to heat
ACU12_RS10355	COG0482	sulfurtransferase activity
ACU12_RS10385	COG4585	Histidine kinase
ACU12_RS10395	COG4191	Histidine kinase
ACU12_RS10415	COG0835	chemotaxis
ACU12_RS10415	COG0784	Response regulator, receiver
ACU12_RS10425	COG1558	bacterial-type flagellum-dependent cell motility
ACU12_RS10430	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ACU12_RS10440	COG4787	bacterial-type flagellum-dependent cell motility
ACU12_RS10475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACU12_RS10480	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ACU12_RS10510	COG2201	protein-glutamate methylesterase activity
ACU12_RS10530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACU12_RS10535	COG4221	oxidoreductase activity
ACU12_RS10540	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_RS10570	COG1677	Flagellar hook-basal body complex protein FliE
ACU12_RS10620	COG3190	flagellar
ACU12_RS10635	COG1684	flagellar biosynthetic protein fliR
ACU12_RS10690	COG0643	Histidine kinase
ACU12_RS10690	COG2198	Histidine kinase
ACU12_RS10690	COG0784	Response regulator, receiver
ACU12_RS10745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACU12_RS10750	COG4774	siderophore transport
ACU12_RS10765	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACU12_RS10770	COG1360	Flagellar Motor Protein
ACU12_RS10775	COG1192	Involved in chromosome partitioning
ACU12_RS10780	COG0835	chemotaxis
ACU12_RS10790	COG0745	RESPONSE REGULATOR receiver
ACU12_RS10800	COG0840	transmembrane signaling receptor activity
ACU12_RS10810	COG0840	transmembrane signaling receptor activity
ACU12_RS10815	COG0840	transmembrane signaling receptor activity
ACU12_RS10825	COG0840	transmembrane signaling receptor activity
ACU12_RS10830	COG0840	transmembrane signaling receptor activity
ACU12_RS10835	COG0840	transmembrane signaling receptor activity
ACU12_RS10840	COG0840	transmembrane signaling receptor activity
ACU12_RS10845	COG0840	transmembrane signaling receptor activity
ACU12_RS10850	COG0840	transmembrane signaling receptor activity
ACU12_RS10855	COG0840	transmembrane signaling receptor activity
ACU12_RS10860	COG0840	transmembrane signaling receptor activity
ACU12_RS10870	COG0835	chemotaxis
ACU12_RS10880	COG0840	transmembrane signaling receptor activity
ACU12_RS10905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACU12_RS10935	COG0318	PFAM AMP-dependent synthetase and ligase
ACU12_RS10940	COG1024	Enoyl-CoA hydratase
ACU12_RS10945	COG2205	protein histidine kinase activity
ACU12_RS10945	COG2198	Histidine kinase
ACU12_RS10945	COG0784	Response regulator, receiver
ACU12_RS10960	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACU12_RS10965	COG3279	Response regulator of the LytR AlgR family
ACU12_RS10980	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACU12_RS10990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACU12_RS10995	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACU12_RS11005	COG0505	Belongs to the CarA family
ACU12_RS11010	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACU12_RS11015	COG2258	MOSC domain
ACU12_RS11020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACU12_RS11070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACU12_RS11095	COG0277	FAD linked oxidase domain protein
ACU12_RS11100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACU12_RS11110	COG0531	amino acid
ACU12_RS11115	COG0531	amino acid
ACU12_RS11120	COG0235	Class ii aldolase
ACU12_RS11125	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ACU12_RS11150	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACU12_RS11150	COG0140	phosphoribosyl-ATP diphosphatase activity
ACU12_RS11160	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACU12_RS11170	COG0131	Imidazoleglycerol-phosphate dehydratase
ACU12_RS11170	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACU12_RS11185	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACU12_RS11195	COG0124	histidyl-tRNA synthetase
ACU12_RS11210	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACU12_RS11225	COG2963	transposase activity
ACU12_RS11230	COG2801	Transposase and inactivated derivatives
ACU12_RS11250	COG2963	transposase activity
ACU12_RS11275	COG1012	belongs to the aldehyde dehydrogenase family
ACU12_RS11295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACU12_RS11300	COG0697	spore germination
ACU12_RS11310	COG0671	phosphoesterase, PA-phosphatase related
ACU12_RS11325	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ACU12_RS11330	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU12_RS11335	COG5001	Diguanylate cyclase
ACU12_RS11335	COG4251	negative regulation of phosphorylation
ACU12_RS11335	COG3706	GGDEF domain
ACU12_RS11335	COG2203	Gaf domain
ACU12_RS11345	COG1472	Belongs to the glycosyl hydrolase 3 family
ACU12_RS11370	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ACU12_RS11390	COG0617	tRNA 3'-terminal CCA addition
ACU12_RS11400	COG1469	GTP cyclohydrolase I activity
ACU12_RS11405	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACU12_RS11410	COG0477	Major facilitator Superfamily
ACU12_RS11420	COG1070	Carbohydrate kinase
ACU12_RS11445	COG0800	Aldolase
ACU12_RS11450	COG4948	Mandelate Racemase Muconate Lactonizing
ACU12_RS11460	COG3734	2-keto-3-deoxy-galactonokinase
ACU12_RS11465	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ACU12_RS11475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACU12_RS11490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACU12_RS11495	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ACU12_RS11505	COG0352	thiamine-phosphate diphosphorylase activity
ACU12_RS11505	COG0351	phosphomethylpyrimidine kinase
ACU12_RS11530	COG0583	DNA-binding transcription factor activity
ACU12_RS11535	COG1741	Belongs to the pirin family
ACU12_RS11575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACU12_RS11580	COG0402	S-adenosylhomocysteine deaminase activity
ACU12_RS11595	COG1509	lysine 2,3-aminomutase activity
ACU12_RS11600	COG3300	MHYT domain
ACU12_RS11600	COG5001	Diguanylate cyclase
ACU12_RS11615	COG0483	inositol monophosphate 1-phosphatase activity
ACU12_RS11620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACU12_RS11640	COG0488	(ABC) transporter
ACU12_RS11645	COG0513	Belongs to the DEAD box helicase family
ACU12_RS11655	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ACU12_RS11665	COG0625	glutathione transferase activity
ACU12_RS11670	COG1278	Cold shock
ACU12_RS11675	COG1671	Belongs to the UPF0178 family
ACU12_RS11680	COG4681	YaeQ
ACU12_RS11685	COG2081	HI0933 family
ACU12_RS11705	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_RS11725	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACU12_RS11735	COG0802	atpase or kinase
ACU12_RS11740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACU12_RS11740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACU12_RS11745	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACU12_RS11760	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACU12_RS11815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACU12_RS11925	COG0835	chemotaxis
ACU12_RS11930	COG0840	transmembrane signaling receptor activity
ACU12_RS11950	COG2969	positive regulation of protein catabolic process
ACU12_RS11955	COG0625	glutathione transferase activity
ACU12_RS11960	COG2857	Cytochrome c1
ACU12_RS11965	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ACU12_RS11970	COG0723	plastoquinol--plastocyanin reductase activity
ACU12_RS11975	COG0741	lytic transglycosylase activity
ACU12_RS11995	COG1702	phosphate starvation-inducible protein PhoH
ACU12_RS12015	COG4535	Mg2 and Co2 transporter CorC
ACU12_RS12030	COG1012	belongs to the aldehyde dehydrogenase family
ACU12_RS12035	COG1177	transmembrane transport
ACU12_RS12040	COG1176	ABC-type spermidine putrescine transport system, permease component I
ACU12_RS12045	COG3842	ATPase activity
ACU12_RS12065	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ACU12_RS12080	COG3501	Rhs element vgr protein
ACU12_RS12080	COG3409	Peptidoglycan-binding domain 1 protein
ACU12_RS12095	COG2201	protein-glutamate methylesterase activity
ACU12_RS12100	COG2801	Transposase and inactivated derivatives
ACU12_RS12140	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACU12_RS12145	COG0174	glutamine synthetase
ACU12_RS12150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU12_RS12160	COG0477	Major facilitator Superfamily
ACU12_RS12165	COG0243	molybdopterin cofactor binding
ACU12_RS12180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACU12_RS12185	COG1121	(ABC) transporter
ACU12_RS12195	COG2733	membrane
ACU12_RS12200	COG2205	protein histidine kinase activity
ACU12_RS12200	COG5002	protein histidine kinase activity
ACU12_RS12200	COG0784	Response regulator, receiver
ACU12_RS12220	COG2902	Dehydrogenase
ACU12_RS12230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU12_RS12235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU12_RS12245	COG1609	Transcriptional regulator
ACU12_RS12250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACU12_RS12250	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACU12_RS12255	COG1105	Belongs to the carbohydrate kinase PfkB family
ACU12_RS12260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACU12_RS12260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACU12_RS12270	COG3039	Transposase
ACU12_RS12295	COG2801	Transposase and inactivated derivatives
ACU12_RS12315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACU12_RS12320	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACU12_RS12325	COG1862	Preprotein translocase
ACU12_RS12330	COG0343	queuine tRNA-ribosyltransferase activity
ACU12_RS12390	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACU12_RS12405	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACU12_RS12410	COG0742	ribosomal rna small subunit methyltransferase
ACU12_RS12415	COG0326	Molecular chaperone. Has ATPase activity
ACU12_RS12460	COG1506	peptidase
ACU12_RS12460	COG0823	Involved in the tonB-independent uptake of proteins
ACU12_RS12475	COG4206	TonB-dependent receptor
ACU12_RS12525	COG0531	amino acid
ACU12_RS12540	COG0006	proline dipeptidase activity
ACU12_RS12550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACU12_RS12565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU12_RS12570	COG3938	Belongs to the proline racemase family
ACU12_RS12580	COG0552	protein localization to endoplasmic reticulum
ACU12_RS12590	COG1194	a g-specific adenine glycosylase
ACU12_RS12600	COG0784	Response regulator, receiver
ACU12_RS12600	COG4191	Histidine kinase
ACU12_RS12605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACU12_RS12630	COG3040	lipid binding
ACU12_RS12640	COG1960	acyl-CoA dehydrogenase activity
ACU12_RS12650	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACU12_RS12680	COG0438	transferase activity, transferring glycosyl groups
ACU12_RS12690	COG0438	transferase activity, transferring glycosyl groups
ACU12_RS12695	COG0438	transferase activity, transferring glycosyl groups
ACU12_RS12765	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACU12_RS12775	COG2963	transposase activity
ACU12_RS12780	COG2801	Transposase and inactivated derivatives
ACU12_RS12800	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACU12_RS12815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACU12_RS12820	COG0077	Prephenate dehydratase
ACU12_RS12820	COG1605	Chorismate mutase
ACU12_RS12825	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ACU12_RS12830	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACU12_RS12875	COG1228	amidohydrolase
ACU12_RS12880	COG2986	histidine ammonia-lyase
ACU12_RS12890	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ACU12_RS12910	COG2963	transposase activity
ACU12_RS12915	COG2801	Transposase and inactivated derivatives
ACU12_RS12925	COG0556	nucleotide-excision repair
ACU12_RS12930	COG4969	Belongs to the N-Me-Phe pilin family
ACU12_RS12995	COG4695	Portal protein
ACU12_RS13040	COG3179	chitinase
ACU12_RS13135	COG1192	Involved in chromosome partitioning
ACU12_RS13245	COG1611	Belongs to the LOG family
ACU12_RS13255	COG2095	MarC family integral membrane protein
ACU12_RS13265	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACU12_RS13300	COG1185	polyribonucleotide nucleotidyltransferase activity
ACU12_RS13305	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACU12_RS13320	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACU12_RS13325	COG0195	Participates in both transcription termination and antitermination
ACU12_RS13330	COG0779	Required for maturation of 30S ribosomal subunits
ACU12_RS13340	COG1007	ATP synthesis coupled electron transport
ACU12_RS13370	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACU12_RS13375	COG1034	ATP synthesis coupled electron transport
ACU12_RS13380	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACU12_RS13385	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ACU12_RS13390	COG0649	NAD binding
ACU12_RS13395	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACU12_RS13405	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACU12_RS13420	COG0149	triose-phosphate isomerase activity
ACU12_RS13430	COG3039	Transposase
ACU12_RS13460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACU12_RS13465	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ACU12_RS13480	COG0133	tryptophan synthase activity
ACU12_RS13490	COG0135	phosphoribosylanthranilate isomerase activity
ACU12_RS13495	COG0101	tRNA pseudouridine synthase activity
ACU12_RS13510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACU12_RS13515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACU12_RS13520	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACU12_RS13525	COG2890	protein-(glutamine-N5) methyltransferase activity
ACU12_RS13545	COG0433	COG0433 Predicted ATPase
ACU12_RS13560	COG2801	Transposase and inactivated derivatives
ACU12_RS13575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACU12_RS13585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACU12_RS13610	COG0717	Belongs to the dCTP deaminase family
ACU12_RS13615	COG0489	protein tyrosine kinase activity
ACU12_RS13620	COG3293	Transposase
ACU12_RS13630	COG3706	GGDEF domain
ACU12_RS13645	COG3039	Transposase
ACU12_RS13655	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_RS13670	COG0415	Belongs to the DNA photolyase family
ACU12_RS13675	COG0305	Participates in initiation and elongation during chromosome replication
ACU12_RS13685	COG0367	asparagine synthase
ACU12_RS13700	COG1960	acyl-CoA dehydrogenase activity
ACU12_RS13715	COG0084	hydrolase, TatD family'
ACU12_RS13720	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACU12_RS13775	COG0386	Belongs to the glutathione peroxidase family
ACU12_RS13870	COG2814	Major facilitator Superfamily
ACU12_RS13875	COG1566	PFAM secretion protein HlyD family protein
ACU12_RS13890	COG2207	Transcriptional regulator
ACU12_RS13910	COG4774	siderophore transport
ACU12_RS13920	COG0367	asparagine synthase
ACU12_RS13925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACU12_RS13935	COG1393	Belongs to the ArsC family
ACU12_RS13995	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACU12_RS14010	COG0233	cytoplasmic translational termination
ACU12_RS14020	COG0575	Belongs to the CDS family
ACU12_RS14025	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ACU12_RS14030	COG0750	zinc metalloprotease
ACU12_RS14040	COG3039	Transposase
ACU12_RS14045	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACU12_RS14050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACU12_RS14055	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACU12_RS14075	COG0825	malonyl-CoA metabolic process
ACU12_RS14100	COG1981	membrane
ACU12_RS14120	COG1695	Transcriptional regulator
ACU12_RS14150	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ACU12_RS14160	COG2040	homocysteine
ACU12_RS14165	COG0833	amino acid
ACU12_RS14170	COG0346	lactoylglutathione lyase activity
ACU12_RS14180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACU12_RS14180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACU12_RS14190	COG2878	Part of a membrane complex involved in electron transport
ACU12_RS14210	COG1595	DNA-templated transcription, initiation
ACU12_RS14235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACU12_RS14250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACU12_RS14255	COG0251	oxidation-reduction process
ACU12_RS14265	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ACU12_RS14265	COG0392	lysyltransferase activity
ACU12_RS14295	COG2814	Major facilitator Superfamily
ACU12_RS14300	COG1902	pentaerythritol trinitrate reductase activity
ACU12_RS14315	COG2824	Alkylphosphonate utilization operon protein PhnA
ACU12_RS14325	COG1047	Peptidyl-prolyl cis-trans
ACU12_RS14360	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACU12_RS14375	COG1451	nucleotide metabolic process
ACU12_RS14390	COG0183	Belongs to the thiolase family
ACU12_RS14420	COG1793	dna ligase
ACU12_RS14420	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ACU12_RS14430	COG1793	dna ligase
ACU12_RS14435	COG1201	RNA secondary structure unwinding
ACU12_RS14450	COG1278	Cold shock
ACU12_RS14455	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ACU12_RS14460	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ACU12_RS14470	COG3046	protein related to deoxyribodipyrimidine photolyase
ACU12_RS14475	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
ACU12_RS14480	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACU12_RS14485	COG2954	triphosphatase activity
ACU12_RS14500	COG1381	Involved in DNA repair and RecF pathway recombination
ACU12_RS14520	COG0681	Belongs to the peptidase S26 family
ACU12_RS14525	COG0481	GTPase activity
ACU12_RS14530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACU12_RS14570	COG1960	acyl-CoA dehydrogenase activity
ACU12_RS14595	COG3250	beta-galactosidase activity
ACU12_RS14630	COG5002	protein histidine kinase activity
ACU12_RS14630	COG0784	Response regulator, receiver
ACU12_RS14635	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_RS14640	COG2205	protein histidine kinase activity
ACU12_RS14640	COG2198	Histidine kinase
ACU12_RS14640	COG0784	Response regulator, receiver
ACU12_RS14645	COG2353	YceI-like domain
ACU12_RS14675	COG1760	l-serine dehydratase
ACU12_RS14685	COG0626	cystathionine gamma-synthase activity
ACU12_RS14690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACU12_RS14695	COG0739	heme binding
ACU12_RS14705	COG1272	protein, Hemolysin III
ACU12_RS14720	COG2982	Protein involved in outer membrane biogenesis
ACU12_RS14725	COG0516	GMP reductase activity
ACU12_RS14725	COG0517	IMP dehydrogenase activity
ACU12_RS14730	COG0463	Glycosyl transferase, family 2
ACU12_RS14740	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ACU12_RS14750	COG4771	TonB-dependent receptor
ACU12_RS14755	COG1309	transcriptional regulator
ACU12_RS14765	COG1960	acyl-CoA dehydrogenase activity
ACU12_RS14790	COG0509	glycine decarboxylation via glycine cleavage system
ACU12_RS14805	COG0330	HflC and HflK could
ACU12_RS14810	COG1742	UPF0060 membrane protein
ACU12_RS14815	COG3956	TIGRFAM MazG family protein
ACU12_RS14825	COG0494	nUDIX hydrolase
ACU12_RS14835	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACU12_RS14840	COG0837	glucose binding
ACU12_RS14855	COG3858	chitin binding
ACU12_RS14855	COG1388	LysM domain
ACU12_RS14860	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ACU12_RS14870	COG1472	Belongs to the glycosyl hydrolase 3 family
ACU12_RS14880	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_RS14890	COG3537	Alpha-1,2-mannosidase
ACU12_RS14930	COG3142	Participates in the control of copper homeostasis
ACU12_RS14935	COG1446	asparaginase
ACU12_RS14970	COG2198	Histidine kinase
ACU12_RS14970	COG0784	Response regulator, receiver
ACU12_RS14970	COG0643	Histidine kinase
ACU12_RS14975	COG0840	transmembrane signaling receptor activity
ACU12_RS14980	COG0835	chemotaxis
ACU12_RS14995	COG0189	ligase activity
ACU12_RS15005	COG1397	ADP-ribosylglycohydrolase
ACU12_RS15015	COG1199	ATP-dependent helicase activity
ACU12_RS15025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACU12_RS15030	COG1215	transferase activity, transferring glycosyl groups
ACU12_RS15040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACU12_RS15095	COG1643	Atp-dependent helicase
ACU12_RS15100	COG0783	Belongs to the Dps family
ACU12_RS15105	COG0514	ATP-dependent DNA helicase (RecQ)
ACU12_RS15120	COG1187	pseudouridine synthase activity
ACU12_RS15130	COG0840	transmembrane signaling receptor activity
ACU12_RS15155	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACU12_RS15165	COG0602	queuosine metabolic process
ACU12_RS15175	COG2885	chlorophyll binding
ACU12_RS15180	COG0823	Involved in the tonB-independent uptake of proteins
ACU12_RS15200	COG0824	Thioesterase
ACU12_RS15205	COG2255	four-way junction helicase activity
ACU12_RS15240	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACU12_RS15255	COG0477	Major facilitator Superfamily
ACU12_RS15270	COG0657	acetylesterase activity
ACU12_RS15270	COG2755	lipolytic protein G-D-S-L family
ACU12_RS15290	COG0488	(ABC) transporter
ACU12_RS15325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACU12_RS15325	COG4651	solute:proton antiporter activity
ACU12_RS15330	COG2801	Transposase and inactivated derivatives
ACU12_RS15345	COG4772	TonB-dependent receptor
ACU12_RS15355	COG4264	IucA IucC family
ACU12_RS15360	COG2814	Major facilitator Superfamily
ACU12_RS15370	COG0019	diaminopimelate decarboxylase activity
ACU12_RS15415	COG4206	TonB-dependent receptor
ACU12_RS15420	COG2801	Transposase and inactivated derivatives
ACU12_RS15425	COG2963	transposase activity
ACU12_RS15430	COG0542	response to heat
ACU12_RS15455	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ACU12_RS15465	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_RS15470	COG0534	Mate efflux family protein
ACU12_RS15480	COG0336	Belongs to the RNA methyltransferase TrmD family
ACU12_RS15485	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACU12_RS15490	COG0228	four-way junction DNA binding
ACU12_RS15515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACU12_RS15520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACU12_RS15560	COG2172	sigma factor antagonist activity
ACU12_RS15565	COG1366	Belongs to the anti-sigma-factor antagonist family
ACU12_RS15570	COG1366	Belongs to the anti-sigma-factor antagonist family
ACU12_RS15585	COG0326	Molecular chaperone. Has ATPase activity
ACU12_RS15590	COG2207	Transcriptional regulator
ACU12_RS15615	COG2963	transposase activity
ACU12_RS15635	COG3209	COG3209 Rhs family protein
ACU12_RS15665	COG3209	COG3209 Rhs family protein
ACU12_RS15685	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ACU12_RS15690	COG1845	cytochrome c oxidase, subunit III
ACU12_RS15695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACU12_RS15710	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACU12_RS15715	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACU12_RS15725	COG0196	riboflavin kinase activity
ACU12_RS15730	COG0728	peptidoglycan biosynthetic process
ACU12_RS15735	COG0268	Binds directly to 16S ribosomal RNA
ACU12_RS15740	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACU12_RS15745	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ACU12_RS15755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACU12_RS15760	COG0824	Thioesterase
ACU12_RS15775	COG1946	Acyl-CoA thioesterase
ACU12_RS15785	COG1595	DNA-templated transcription, initiation
ACU12_RS15800	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ACU12_RS15815	COG3293	Transposase
ACU12_RS15845	COG1877	trehalose-phosphatase activity
ACU12_RS15850	COG3387	PFAM Glycoside hydrolase 15-related
ACU12_RS15865	COG0840	transmembrane signaling receptor activity
ACU12_RS15870	COG3011	Protein conserved in bacteria
ACU12_RS15885	COG0564	pseudouridine synthase activity
ACU12_RS15890	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU12_RS15895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACU12_RS15895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACU12_RS15905	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ACU12_RS15910	COG0045	succinate-CoA ligase (ADP-forming) activity
ACU12_RS15925	COG2184	nucleotidyltransferase activity
ACU12_RS15945	COG2194	sulfuric ester hydrolase activity
ACU12_RS15950	COG4969	Belongs to the N-Me-Phe pilin family
ACU12_RS15960	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ACU12_RS15970	COG3039	Transposase
ACU12_RS15980	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_RS15995	COG2963	transposase activity
ACU12_RS16020	COG0745	RESPONSE REGULATOR receiver
ACU12_RS16065	COG3039	Transposase
ACU12_RS16120	COG2022	thiamine diphosphate biosynthetic process
ACU12_RS16130	COG3273	potassium ion transport
ACU12_RS16130	COG0471	metal ion transport
ACU12_RS16150	COG1970	mechanosensitive ion channel activity
ACU12_RS16155	COG3328	transposase activity
ACU12_RS16165	COG2963	transposase activity
ACU12_RS16175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACU12_RS16195	COG0308	aminopeptidase N
ACU12_RS16200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU12_RS16210	COG0529	Catalyzes the synthesis of activated sulfate
ACU12_RS16210	COG2895	sulfate adenylyltransferase (ATP) activity
ACU12_RS16215	COG0175	sulfate reduction
ACU12_RS16220	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACU12_RS16225	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACU12_RS16230	COG0175	sulfate reduction
ACU12_RS16250	COG2198	Histidine kinase
ACU12_RS16250	COG2205	protein histidine kinase activity
ACU12_RS16250	COG0784	Response regulator, receiver
ACU12_RS16285	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ACU12_RS16290	COG3588	fructose-bisphosphate aldolase
ACU12_RS16295	COG0469	pyruvate kinase activity
ACU12_RS16305	COG0126	phosphoglycerate kinase activity
ACU12_RS16315	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACU12_RS16335	COG3453	Protein conserved in bacteria
ACU12_RS16335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACU12_RS16340	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACU12_RS16345	COG4149	molybdate abc transporter
ACU12_RS16350	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ACU12_RS16395	COG1022	Amp-dependent synthetase and ligase
ACU12_RS16440	COG1376	ErfK ybiS ycfS ynhG family protein
ACU12_RS16450	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACU12_RS16455	COG1301	dicarboxylic acid transport
ACU12_RS16460	COG2963	transposase activity
ACU12_RS16465	COG2801	Transposase and inactivated derivatives
ACU12_RS16485	COG2304	oxidoreductase activity
ACU12_RS16505	COG0714	Associated with various cellular activities
ACU12_RS16535	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACU12_RS16560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACU12_RS16570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACU12_RS16585	COG1561	YicC-like family, N-terminal region
ACU12_RS16590	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ACU12_RS16595	COG0346	lactoylglutathione lyase activity
ACU12_RS16605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACU12_RS16630	COG0006	proline dipeptidase activity
ACU12_RS16650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACU12_RS16670	COG2912	Transglutaminase-like superfamily
ACU12_RS16675	COG1773	rubredoxin
ACU12_RS16680	COG0352	thiamine-phosphate diphosphorylase activity
ACU12_RS16690	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACU12_RS16710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACU12_RS16745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACU12_RS16750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACU12_RS16770	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_RS16785	COG3781	membrane
ACU12_RS16795	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACU12_RS16835	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ACU12_RS16845	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACU12_RS16865	COG3710	Transcriptional regulator
ACU12_RS16870	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACU12_RS16875	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACU12_RS16905	COG2226	methyltransferase
ACU12_RS16910	COG0066	3-isopropylmalate dehydratase activity
ACU12_RS16915	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACU12_RS16935	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACU12_RS16940	COG1538	Outer membrane efflux protein
ACU12_RS16945	COG1519	Transferase
ACU12_RS16950	COG1560	Kdo2-lipid A biosynthetic process
ACU12_RS16980	COG0280	phosphate acetyltransferase
ACU12_RS16980	COG0281	malic enzyme
ACU12_RS16995	COG4191	Histidine kinase
ACU12_RS17010	COG0583	DNA-binding transcription factor activity
ACU12_RS17035	COG2197	response regulator
ACU12_RS17045	COG0642	Histidine kinase
ACU12_RS17060	COG2851	Citrate transporter
ACU12_RS17065	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_RS17070	COG1609	Transcriptional regulator
ACU12_RS17075	COG2211	Major facilitator Superfamily
ACU12_RS17105	COG0436	Aminotransferase
ACU12_RS17120	COG0726	polysaccharide deacetylase
ACU12_RS17125	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACU12_RS17145	COG3964	amidohydrolase
ACU12_RS17150	COG0402	S-adenosylhomocysteine deaminase activity
ACU12_RS17170	COG0242	peptide deformylase activity
ACU12_RS17185	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ACU12_RS17230	COG2188	Transcriptional regulator
ACU12_RS17240	COG1450	Type ii and iii secretion system protein
ACU12_RS17255	COG3166	PFAM Fimbrial assembly family protein
ACU12_RS17260	COG3156	type II secretion system protein K
ACU12_RS17265	COG4795	General secretion pathway protein
ACU12_RS17270	COG2165	general secretion pathway protein
ACU12_RS17275	COG4970	Tfp pilus assembly protein FimT
ACU12_RS17280	COG2165	general secretion pathway protein
ACU12_RS17285	COG1459	type II secretion system
ACU12_RS17295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACU12_RS17300	COG1404	Belongs to the peptidase S8 family
ACU12_RS17305	COG5295	Hep Hag repeat protein
ACU12_RS17310	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACU12_RS17310	COG0047	phosphoribosylformylglycinamidine synthase activity
ACU12_RS17315	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACU12_RS17320	COG4974	Belongs to the 'phage' integrase family
ACU12_RS17335	COG0795	lipopolysaccharide-transporting ATPase activity
ACU12_RS17345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACU12_RS17360	COG0525	valine-tRNA ligase activity
ACU12_RS17385	COG1183	phosphatidylcholine synthase activity
ACU12_RS17395	COG0442	prolyl-tRNA aminoacylation
ACU12_RS17410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACU12_RS17415	COG1127	ABC transporter
ACU12_RS17420	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACU12_RS17420	COG3218	ABC-type transport auxiliary lipoprotein component
ACU12_RS17455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACU12_RS17460	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ACU12_RS17460	COG0662	Cupin 2, conserved barrel domain protein
ACU12_RS17485	COG2086	electron transfer activity
ACU12_RS17500	COG0546	phosphoglycolate phosphatase activity
ACU12_RS17500	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACU12_RS17505	COG0277	FAD linked oxidase domain protein
ACU12_RS17520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACU12_RS17555	COG3754	Rhamnan synthesis protein F
ACU12_RS17560	COG1216	Glycosyl transferase, family 2
ACU12_RS17560	COG0438	transferase activity, transferring glycosyl groups
ACU12_RS17565	COG0110	maltose O-acetyltransferase activity
ACU12_RS17580	COG0626	cystathionine gamma-synthase activity
ACU12_RS17615	COG0625	glutathione transferase activity
ACU12_RS17625	COG0513	Belongs to the DEAD box helicase family
ACU12_RS17630	COG0720	synthase
ACU12_RS17640	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACU12_RS17645	COG1956	GAF domain-containing protein
ACU12_RS17655	COG0546	phosphoglycolate phosphatase activity
ACU12_RS17680	COG0339	signal peptide processing
ACU12_RS17720	COG3039	Transposase
ACU12_RS17735	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACU12_RS17740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU12_RS17745	COG1136	(ABC) transporter
ACU12_RS17755	COG0577	efflux transmembrane transporter activity
ACU12_RS17755	COG1136	(ABC) transporter
ACU12_RS17765	COG0577	efflux transmembrane transporter activity
ACU12_RS17765	COG1136	(ABC) transporter
ACU12_RS17775	COG4191	Histidine kinase
ACU12_RS17800	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACU12_RS17805	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACU12_RS17810	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACU12_RS17820	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACU12_RS17830	COG0356	it plays a direct role in the translocation of protons across the membrane
ACU12_RS17850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACU12_RS17860	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACU12_RS17895	COG2011	ABC-type metal ion transport system permease component
ACU12_RS17905	COG0697	spore germination
ACU12_RS17940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACU12_RS17945	COG1187	pseudouridine synthase activity
ACU12_RS17950	COG2813	Specifically methylates the guanine in position
ACU12_RS17975	COG2202	Pas domain
ACU12_RS17975	COG2205	protein histidine kinase activity
ACU12_RS18000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU12_RS18045	COG0745	RESPONSE REGULATOR receiver
ACU12_RS18060	COG1404	Belongs to the peptidase S8 family
ACU12_RS18075	COG0842	Transport permease protein
ACU12_RS18080	COG1131	(ABC) transporter
ACU12_RS18085	COG0025	NhaP-type Na H and K H
ACU12_RS18090	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ACU12_RS18095	COG1573	uracil-dna glycosylase
ACU12_RS18105	COG3384	dioxygenase
ACU12_RS18120	COG0667	Aldo Keto reductase
ACU12_RS18135	COG3590	peptidase
ACU12_RS18150	COG0531	amino acid
ACU12_RS18165	COG2972	Histidine kinase
ACU12_RS18205	COG1271	oxidase subunit
ACU12_RS18210	COG1294	oxidase, subunit
ACU12_RS18225	COG1063	alcohol dehydrogenase
ACU12_RS18305	COG2801	Transposase and inactivated derivatives
ACU12_RS18310	COG2353	YceI-like domain
ACU12_RS18345	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ACU12_RS18360	COG3386	PFAM SMP-30 Gluconolaconase
ACU12_RS18375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACU12_RS18390	COG0459	protein refolding
ACU12_RS18420	COG1252	NADH dehydrogenase
ACU12_RS18425	COG2860	membrane
ACU12_RS18430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACU12_RS18435	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACU12_RS18440	COG2201	protein-glutamate methylesterase activity
ACU12_RS18445	COG2177	Part of the ABC transporter FtsEX involved in
ACU12_RS18450	COG2884	Cell division ATP-binding protein ftsE
ACU12_RS18460	COG3118	belongs to the thioredoxin family
ACU12_RS18465	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACU12_RS18495	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACU12_RS18495	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACU12_RS18505	COG1473	amidohydrolase
ACU12_RS18510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU12_RS18515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU12_RS18545	COG5383	Protein conserved in bacteria
ACU12_RS18585	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ACU12_RS18590	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACU12_RS18600	COG4948	Mandelate Racemase Muconate Lactonizing
ACU12_RS18610	COG0531	amino acid
ACU12_RS18625	COG4682	membrane
ACU12_RS18630	COG2133	pyrroloquinoline quinone binding
ACU12_RS18645	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACU12_RS18650	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACU12_RS18660	COG1610	YqeY-like protein
ACU12_RS18665	COG1295	ribonuclease BN
ACU12_RS18670	COG0358	DNA primase activity
ACU12_RS18720	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ACU12_RS18735	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACU12_RS18760	COG2963	transposase activity
ACU12_RS18795	COG0739	heme binding
ACU12_RS18810	COG2211	Major facilitator Superfamily
ACU12_RS18815	COG0708	Exodeoxyribonuclease III
ACU12_RS18855	COG2111	Na H antiporter
ACU12_RS18855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACU12_RS18860	COG1006	Multisubunit Na H antiporter MnhC subunit
ACU12_RS18865	COG0651	ATP synthesis coupled electron transport
ACU12_RS18875	COG2212	antiporter activity
ACU12_RS18880	COG1320	monovalent cation:proton antiporter activity
ACU12_RS18885	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ACU12_RS18915	COG3104	oligopeptide transport
ACU12_RS18920	COG3483	tryptophan 2,3-dioxygenase activity
ACU12_RS18930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACU12_RS18945	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACU12_RS18955	COG3039	Transposase
ACU12_RS18960	COG3039	Transposase
ACU12_RS18970	COG0513	Belongs to the DEAD box helicase family
ACU12_RS19030	COG2963	transposase activity
ACU12_RS19035	COG2801	Transposase and inactivated derivatives
ACU12_RS19055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACU12_RS19060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACU12_RS19070	COG0045	succinate-CoA ligase (ADP-forming) activity
ACU12_RS19070	COG1042	CoA-binding domain protein
ACU12_RS19070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACU12_RS19080	COG2239	Acts as a magnesium transporter
ACU12_RS19100	COG3039	Transposase
ACU12_RS19105	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACU12_RS19110	COG3387	PFAM Glycoside hydrolase 15-related
ACU12_RS19125	COG3100	YcgL domain-containing protein
ACU12_RS19130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACU12_RS19140	COG0463	Glycosyl transferase, family 2
ACU12_RS19160	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_RS19205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACU12_RS19220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACU12_RS19240	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_RS19265	COG0408	coproporphyrinogen oxidase activity
ACU12_RS19330	COG0210	DNA helicase
ACU12_RS19345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU12_RS19350	COG0583	DNA-binding transcription factor activity
ACU12_RS19355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACU12_RS19365	COG2159	amidohydrolase
ACU12_RS19390	COG0357	Ribosomal RNA small subunit methyltransferase G
ACU12_RS19395	COG3540	Alkaline phosphatase
ACU12_RS19405	COG2091	lysine biosynthetic process via aminoadipic acid
ACU12_RS19420	COG0708	Exodeoxyribonuclease III
ACU12_RS19430	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACU12_RS19435	COG3162	membrane
ACU12_RS19465	COG0738	Major facilitator superfamily
ACU12_RS19470	COG1414	Transcriptional regulator
ACU12_RS19480	COG2205	protein histidine kinase activity
ACU12_RS19495	COG3459	Glycosyltransferase 36 associated
ACU12_RS19505	COG3265	gluconokinase activity
ACU12_RS19510	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU12_RS19530	COG0339	signal peptide processing
ACU12_RS19555	COG0564	pseudouridine synthase activity
ACU12_RS19570	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACU12_RS19585	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACU12_RS19600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACU12_RS19605	COG0318	PFAM AMP-dependent synthetase and ligase
ACU12_RS19610	COG0727	PFAM Uncharacterised protein family (UPF0153)
ACU12_RS19615	COG0596	Alpha beta hydrolase
ACU12_RS19620	COG3177	Filamentation induced by cAMP protein fic
ACU12_RS19625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACU12_RS19640	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACU12_RS19665	COG2205	protein histidine kinase activity
ACU12_RS19670	COG0028	Belongs to the TPP enzyme family
ACU12_RS19685	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ACU12_RS19690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACU12_RS19730	COG0183	Belongs to the thiolase family
ACU12_RS19745	COG3039	Transposase
ACU12_RS19750	COG3039	Transposase
ACU12_RS19765	COG2032	superoxide dismutase activity
ACU12_RS19770	COG2032	superoxide dismutase activity
ACU12_RS19775	COG2204	response regulator
ACU12_RS19780	COG3852	Histidine kinase
ACU12_RS19785	COG0004	ammonium transporteR
ACU12_RS19790	COG0347	Belongs to the P(II) protein family
ACU12_RS19795	COG0174	glutamine synthetase
ACU12_RS19800	COG1968	undecaprenyl-diphosphatase activity
ACU12_RS19845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU12_RS19855	COG2062	phosphohistidine phosphatase, SixA
ACU12_RS19860	COG0489	protein tyrosine kinase activity
ACU12_RS19880	COG1396	sequence-specific DNA binding
ACU12_RS19885	COG3550	peptidyl-serine autophosphorylation
ACU12_RS19890	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ACU12_RS19895	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACU12_RS19910	COG0517	IMP dehydrogenase activity
ACU12_RS19910	COG1125	glycine betaine transport
ACU12_RS19925	COG1119	ATPase activity
ACU12_RS19935	COG1473	amidohydrolase
ACU12_RS19940	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACU12_RS19945	COG4773	Receptor
ACU12_RS19950	COG1522	sequence-specific DNA binding
ACU12_RS19955	COG3186	Phenylalanine-4-hydroxylase
ACU12_RS19965	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_RS19975	COG1609	Transcriptional regulator
ACU12_RS19995	COG0366	Alpha amylase catalytic
ACU12_RS20000	COG0366	Alpha amylase catalytic
ACU12_RS20015	COG3039	Transposase
ACU12_RS20025	COG2963	transposase activity
ACU12_RS20080	COG0676	glucose-6-phosphate 1-epimerase activity
ACU12_RS20095	COG0730	response to heat
ACU12_RS20130	COG0302	gtp cyclohydrolase
ACU12_RS20155	COG0477	Major facilitator Superfamily
ACU12_RS20185	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_RS20215	COG3237	CsbD-like
ACU12_RS20265	COG0477	Major facilitator Superfamily
ACU12_RS20285	COG3039	Transposase
ACU12_RS20290	COG2963	transposase activity
ACU12_RS20295	COG2801	Transposase and inactivated derivatives
ACU12_RS20300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU12_RS20330	COG1755	Isoprenylcysteine carboxyl methyltransferase
ACU12_RS20335	COG1304	FMN binding
ACU12_RS20340	COG3039	Transposase
ACU12_RS20350	COG4772	TonB-dependent receptor
ACU12_RS20360	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ACU12_RS20380	COG1272	protein, Hemolysin III
ACU12_RS20385	COG1111	helicase
ACU12_RS20385	COG1205	dead DEAH box helicase
ACU12_RS20435	COG0070	glutamate synthase
ACU12_RS20435	COG0069	glutamate synthase activity
ACU12_RS20435	COG0067	glutamate synthase
ACU12_RS20440	COG0493	'glutamate synthase
ACU12_RS20455	COG0531	amino acid
ACU12_RS20465	COG1322	Protein conserved in bacteria
ACU12_RS20475	COG0386	Belongs to the glutathione peroxidase family
ACU12_RS20480	COG2853	Lipoprotein
ACU12_RS20495	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACU12_RS20500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACU12_RS20505	COG1127	ABC transporter
ACU12_RS20530	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ACU12_RS20535	COG1074	ATP-dependent DNA helicase activity
ACU12_RS20545	COG3549	Plasmid maintenance system killer
ACU12_RS20640	COG2124	cytochrome p450
ACU12_RS20645	COG2124	cytochrome p450
ACU12_RS20650	COG1141	Ferredoxin
ACU12_RS20655	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_RS20660	COG2124	cytochrome p450
ACU12_RS20665	COG0142	geranyltranstransferase activity
ACU12_RS20670	COG1657	PFAM Prenyltransferase squalene oxidase
ACU12_RS20680	COG1304	FMN binding
ACU12_RS20710	COG0564	pseudouridine synthase activity
ACU12_RS20735	COG3706	GGDEF domain
ACU12_RS20745	COG1929	Belongs to the glycerate kinase type-1 family
ACU12_RS20750	COG2271	Major facilitator Superfamily
ACU12_RS20765	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACU12_RS20770	COG0861	Integral membrane protein TerC family
ACU12_RS20780	COG0584	glycerophosphoryl diester phosphodiesterase
ACU12_RS20790	COG0671	phosphoesterase, PA-phosphatase related
ACU12_RS20795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACU12_RS20800	COG0726	polysaccharide deacetylase
ACU12_RS20850	COG2801	Transposase and inactivated derivatives