locus-tag	class	description
FE36_RS00010	COG1064	alcohol dehydrogenase
FE36_RS00015	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FE36_RS00020	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FE36_RS00025	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FE36_RS00035	COG2234	aminopeptidase activity
FE36_RS00045	COG4942	peptidase
FE36_RS00050	COG0793	Belongs to the peptidase S41A family
FE36_RS00085	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FE36_RS00090	COG1304	FMN binding
FE36_RS00100	COG1657	PFAM Prenyltransferase squalene oxidase
FE36_RS00105	COG0142	geranyltranstransferase activity
FE36_RS00110	COG2124	cytochrome p450
FE36_RS00115	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_RS00120	COG1141	Ferredoxin
FE36_RS00125	COG2124	cytochrome p450
FE36_RS00130	COG2124	cytochrome p450
FE36_RS00195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FE36_RS00200	COG1074	ATP-dependent DNA helicase activity
FE36_RS00205	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FE36_RS00240	COG1127	ABC transporter
FE36_RS00245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FE36_RS00250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FE36_RS00265	COG2853	Lipoprotein
FE36_RS00270	COG0386	Belongs to the glutathione peroxidase family
FE36_RS00280	COG1322	Protein conserved in bacteria
FE36_RS00290	COG0531	amino acid
FE36_RS00295	COG0493	'glutamate synthase
FE36_RS00300	COG0069	glutamate synthase activity
FE36_RS00300	COG0067	glutamate synthase
FE36_RS00300	COG0070	glutamate synthase
FE36_RS00350	COG1205	dead DEAH box helicase
FE36_RS00350	COG1111	helicase
FE36_RS00355	COG1272	protein, Hemolysin III
FE36_RS00370	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FE36_RS00380	COG4772	TonB-dependent receptor
FE36_RS00395	COG3039	Transposase
FE36_RS00465	COG3237	CsbD-like
FE36_RS00500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE36_RS00510	COG0477	Major facilitator Superfamily
FE36_RS00530	COG0302	gtp cyclohydrolase
FE36_RS00580	COG0676	glucose-6-phosphate 1-epimerase activity
FE36_RS00600	COG3135	benzoate transporter
FE36_RS00630	COG0366	Alpha amylase catalytic
FE36_RS00635	COG0366	Alpha amylase catalytic
FE36_RS00655	COG1609	Transcriptional regulator
FE36_RS00665	COG2755	lipolytic protein G-D-S-L family
FE36_RS00675	COG3186	Phenylalanine-4-hydroxylase
FE36_RS00680	COG1522	sequence-specific DNA binding
FE36_RS00690	COG1752	Esterase of the alpha-beta hydrolase superfamily
FE36_RS00695	COG1473	amidohydrolase
FE36_RS00705	COG1119	ATPase activity
FE36_RS00720	COG1125	glycine betaine transport
FE36_RS00720	COG0517	IMP dehydrogenase activity
FE36_RS00735	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FE36_RS00740	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FE36_RS00745	COG3550	peptidyl-serine autophosphorylation
FE36_RS00750	COG1396	sequence-specific DNA binding
FE36_RS00770	COG0489	protein tyrosine kinase activity
FE36_RS00775	COG2062	phosphohistidine phosphatase, SixA
FE36_RS00785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE36_RS00830	COG1968	undecaprenyl-diphosphatase activity
FE36_RS00835	COG0174	glutamine synthetase
FE36_RS00840	COG0347	Belongs to the P(II) protein family
FE36_RS00845	COG0004	ammonium transporteR
FE36_RS00850	COG3852	Histidine kinase
FE36_RS00855	COG2204	response regulator
FE36_RS00860	COG2032	superoxide dismutase activity
FE36_RS00865	COG2032	superoxide dismutase activity
FE36_RS00885	COG0183	Belongs to the thiolase family
FE36_RS00925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FE36_RS00930	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FE36_RS00945	COG0028	Belongs to the TPP enzyme family
FE36_RS00950	COG4191	Histidine kinase
FE36_RS00975	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FE36_RS00990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FE36_RS00995	COG3177	Filamentation induced by cAMP protein fic
FE36_RS01000	COG0596	Alpha beta hydrolase
FE36_RS01005	COG0727	PFAM Uncharacterised protein family (UPF0153)
FE36_RS01010	COG0318	PFAM AMP-dependent synthetase and ligase
FE36_RS01015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE36_RS01030	COG1181	Belongs to the D-alanine--D-alanine ligase family
FE36_RS01045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FE36_RS01060	COG0564	pseudouridine synthase activity
FE36_RS01080	COG0339	signal peptide processing
FE36_RS01095	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE36_RS01100	COG3265	gluconokinase activity
FE36_RS01110	COG3459	Glycosyltransferase 36 associated
FE36_RS01125	COG2205	protein histidine kinase activity
FE36_RS01135	COG1414	Transcriptional regulator
FE36_RS01140	COG0738	Major facilitator superfamily
FE36_RS01170	COG3162	membrane
FE36_RS01175	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE36_RS01190	COG0708	Exodeoxyribonuclease III
FE36_RS01205	COG2091	lysine biosynthetic process via aminoadipic acid
FE36_RS01215	COG3540	Alkaline phosphatase
FE36_RS01220	COG0357	Ribosomal RNA small subunit methyltransferase G
FE36_RS01245	COG2159	amidohydrolase
FE36_RS01260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FE36_RS01265	COG0583	DNA-binding transcription factor activity
FE36_RS01270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE36_RS01285	COG0210	DNA helicase
FE36_RS01350	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_RS01380	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FE36_RS01395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FE36_RS01435	COG0408	coproporphyrinogen oxidase activity
FE36_RS01445	COG0463	Glycosyl transferase, family 2
FE36_RS01455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FE36_RS01460	COG3100	YcgL domain-containing protein
FE36_RS01475	COG3387	PFAM Glycoside hydrolase 15-related
FE36_RS01480	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FE36_RS01505	COG2239	Acts as a magnesium transporter
FE36_RS01515	COG1042	CoA-binding domain protein
FE36_RS01515	COG0045	succinate-CoA ligase (ADP-forming) activity
FE36_RS01515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FE36_RS01525	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FE36_RS01530	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FE36_RS01570	COG0513	Belongs to the DEAD box helicase family
FE36_RS01580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE36_RS01605	COG1755	Isoprenylcysteine carboxyl methyltransferase
FE36_RS01610	COG1304	FMN binding
FE36_RS01615	COG3039	Transposase
FE36_RS01625	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE36_RS01640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FE36_RS01650	COG3483	tryptophan 2,3-dioxygenase activity
FE36_RS01655	COG3104	oligopeptide transport
FE36_RS01685	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FE36_RS01690	COG1320	monovalent cation:proton antiporter activity
FE36_RS01695	COG2212	antiporter activity
FE36_RS01705	COG0651	ATP synthesis coupled electron transport
FE36_RS01710	COG1006	Multisubunit Na H antiporter MnhC subunit
FE36_RS01715	COG2111	Na H antiporter
FE36_RS01715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FE36_RS01735	COG0708	Exodeoxyribonuclease III
FE36_RS01740	COG2211	Major facilitator Superfamily
FE36_RS01755	COG0739	heme binding
FE36_RS01775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FE36_RS01790	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FE36_RS01840	COG0358	DNA primase activity
FE36_RS01845	COG1295	ribonuclease BN
FE36_RS01850	COG1610	YqeY-like protein
FE36_RS01860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FE36_RS01865	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FE36_RS01880	COG2133	pyrroloquinoline quinone binding
FE36_RS01885	COG4682	membrane
FE36_RS01900	COG0531	amino acid
FE36_RS01910	COG4948	Mandelate Racemase Muconate Lactonizing
FE36_RS01920	COG3023	N-Acetylmuramoyl-L-alanine amidase
FE36_RS01925	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FE36_RS01965	COG5383	Protein conserved in bacteria
FE36_RS01990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE36_RS01995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE36_RS02000	COG1473	amidohydrolase
FE36_RS02010	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FE36_RS02010	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FE36_RS02040	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FE36_RS02045	COG3118	belongs to the thioredoxin family
FE36_RS02055	COG2884	Cell division ATP-binding protein ftsE
FE36_RS02060	COG2177	Part of the ABC transporter FtsEX involved in
FE36_RS02065	COG2201	protein-glutamate methylesterase activity
FE36_RS02070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FE36_RS02075	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FE36_RS02080	COG2860	membrane
FE36_RS02085	COG1252	NADH dehydrogenase
FE36_RS02110	COG0459	protein refolding
FE36_RS02125	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FE36_RS02140	COG3386	PFAM SMP-30 Gluconolaconase
FE36_RS02150	COG4221	oxidoreductase activity
FE36_RS02200	COG0697	spore germination
FE36_RS02205	COG4305	rare lipoprotein A
FE36_RS02215	COG1113	amino acid transport
FE36_RS02225	COG0598	Magnesium transport protein CorA
FE36_RS02285	COG0659	secondary active sulfate transmembrane transporter activity
FE36_RS02310	COG3275	phosphorelay sensor kinase activity
FE36_RS02320	COG0181	hydroxymethylbilane synthase activity
FE36_RS02345	COG1505	serine-type exopeptidase activity
FE36_RS02355	COG0436	Aminotransferase
FE36_RS02365	COG2832	Protein of unknown function (DUF454)
FE36_RS02385	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FE36_RS02425	COG3300	MHYT domain
FE36_RS02425	COG5001	Diguanylate cyclase
FE36_RS02445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE36_RS02450	COG1077	Cell shape determining protein MreB Mrl
FE36_RS02455	COG1792	Involved in formation and maintenance of cell shape
FE36_RS02470	COG0772	Belongs to the SEDS family
FE36_RS02490	COG2951	lytic endotransglycosylase activity
FE36_RS02495	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FE36_RS02505	COG1686	Belongs to the peptidase S11 family
FE36_RS02515	COG2921	Belongs to the UPF0250 family
FE36_RS02540	COG1056	cytidyltransferase-related domain
FE36_RS02540	COG1051	belongs to the nudix hydrolase family
FE36_RS02580	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FE36_RS02585	COG0673	inositol 2-dehydrogenase activity
FE36_RS02590	COG2823	Periplasmic or secreted lipoprotein
FE36_RS02595	COG4251	negative regulation of phosphorylation
FE36_RS02600	COG0784	Response regulator, receiver
FE36_RS02605	COG4191	Histidine kinase
FE36_RS02610	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FE36_RS02630	COG2801	Transposase and inactivated derivatives
FE36_RS02640	COG3250	beta-galactosidase activity
FE36_RS02655	COG2188	Transcriptional regulator
FE36_RS02665	COG1609	Transcriptional regulator
FE36_RS02670	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FE36_RS02675	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FE36_RS02685	COG1215	transferase activity, transferring glycosyl groups
FE36_RS02690	COG1649	PFAM Uncharacterised BCR, COG1649
FE36_RS02690	COG0726	polysaccharide deacetylase
FE36_RS02710	COG1012	belongs to the aldehyde dehydrogenase family
FE36_RS02740	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FE36_RS02755	COG2205	protein histidine kinase activity
FE36_RS02805	COG3791	Glutathione-dependent formaldehyde-activating
FE36_RS02830	COG0488	(ABC) transporter
FE36_RS02850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FE36_RS02860	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FE36_RS02870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FE36_RS02870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FE36_RS02890	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FE36_RS02895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FE36_RS02900	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FE36_RS02920	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FE36_RS02925	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FE36_RS02935	COG2205	protein histidine kinase activity
FE36_RS02940	COG0745	RESPONSE REGULATOR receiver
FE36_RS02945	COG0277	FAD linked oxidase domain protein
FE36_RS02950	COG1988	membrane-bound metal-dependent
FE36_RS02955	COG0792	nuclease activity
FE36_RS02990	COG0275	rRNA processing
FE36_RS02995	COG3116	cell division
FE36_RS03010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FE36_RS03015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FE36_RS03030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FE36_RS03035	COG1181	Belongs to the D-alanine--D-alanine ligase family
FE36_RS03040	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FE36_RS03055	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FE36_RS03065	COG4942	peptidase
FE36_RS03065	COG1388	LysM domain
FE36_RS03080	COG0494	nUDIX hydrolase
FE36_RS03090	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FE36_RS03100	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_RS03100	COG3321	synthase
FE36_RS03100	COG0604	alcohol dehydrogenase
FE36_RS03145	COG2226	methyltransferase
FE36_RS03150	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FE36_RS03185	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FE36_RS03200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FE36_RS03215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE36_RS03220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FE36_RS03230	COG0667	Aldo Keto reductase
FE36_RS03265	COG2175	clavaminate synthase activity
FE36_RS03275	COG4181	ATPase activity
FE36_RS03290	COG0642	Histidine kinase
FE36_RS03300	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FE36_RS03320	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FE36_RS03340	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FE36_RS03345	COG2967	ApaG domain
FE36_RS03350	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FE36_RS03355	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FE36_RS03370	COG0123	including yeast histone deacetylase and acetoin utilization protein
FE36_RS03375	COG2096	Adenosyltransferase
FE36_RS03385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE36_RS03390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE36_RS03420	COG3384	dioxygenase
FE36_RS03425	COG0583	DNA-binding transcription factor activity
FE36_RS03430	COG0318	PFAM AMP-dependent synthetase and ligase
FE36_RS03440	COG1024	Enoyl-CoA hydratase
FE36_RS03460	COG3386	PFAM SMP-30 Gluconolaconase
FE36_RS03485	COG0697	spore germination
FE36_RS03515	COG2197	response regulator
FE36_RS03525	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FE36_RS03530	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FE36_RS03540	COG0583	DNA-binding transcription factor activity
FE36_RS03545	COG3634	alkyl hydroperoxide reductase activity
FE36_RS03555	COG2890	protein-(glutamine-N5) methyltransferase activity
FE36_RS03600	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FE36_RS03640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FE36_RS03650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FE36_RS03675	COG1295	ribonuclease BN
FE36_RS03680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FE36_RS03700	COG0521	Mo-molybdopterin cofactor biosynthetic process
FE36_RS03710	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FE36_RS03715	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FE36_RS03725	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FE36_RS03740	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FE36_RS03750	COG0193	aminoacyl-tRNA hydrolase activity
FE36_RS03755	COG0012	GTP binding
FE36_RS03785	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FE36_RS03790	COG0250	Participates in transcription elongation, termination and antitermination
FE36_RS03795	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FE36_RS03800	COG0081	regulation of translation
FE36_RS03805	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FE36_RS03815	COG0085	RNA polymerase activity
FE36_RS03820	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FE36_RS03825	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FE36_RS03830	COG0049	tRNA binding
FE36_RS03840	COG0051	transcription antitermination factor activity, RNA binding
FE36_RS03850	COG0088	Forms part of the polypeptide exit tunnel
FE36_RS03855	COG0089	rRNA binding
FE36_RS03860	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FE36_RS03880	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FE36_RS03885	COG0255	Belongs to the universal ribosomal protein uL29 family
FE36_RS03890	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FE36_RS03895	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FE36_RS03900	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FE36_RS03905	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FE36_RS03935	COG1841	ribosomal large subunit assembly
FE36_RS03940	COG0200	Binds to the 23S rRNA
FE36_RS03945	COG0201	protein transport
FE36_RS03955	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FE36_RS03960	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FE36_RS03970	COG0203	ribosomal protein L17
FE36_RS03975	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FE36_RS03985	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FE36_RS04005	COG1217	gtp-binding protein TYPA
FE36_RS04010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FE36_RS04035	COG0584	glycerophosphoryl diester phosphodiesterase
FE36_RS04060	COG1902	pentaerythritol trinitrate reductase activity
FE36_RS04060	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE36_RS04065	COG0604	alcohol dehydrogenase
FE36_RS04090	COG0156	8-amino-7-oxononanoate synthase activity
FE36_RS04095	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FE36_RS04100	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FE36_RS04105	COG4208	sulfate ABC transporter
FE36_RS04110	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FE36_RS04140	COG0406	alpha-ribazole phosphatase activity
FE36_RS04145	COG0285	dihydrofolate synthase activity
FE36_RS04165	COG2833	Protein of unknown function (DUF455)
FE36_RS04170	COG3291	Pkd domain containing protein
FE36_RS04180	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE36_RS04185	COG0671	phosphoesterase, PA-phosphatase related
FE36_RS04190	COG0438	transferase activity, transferring glycosyl groups
FE36_RS04200	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FE36_RS04215	COG4783	chaperone-mediated protein folding
FE36_RS04230	COG0473	3-isopropylmalate dehydrogenase activity
FE36_RS04270	COG0544	peptidyl-prolyl cis-trans isomerase activity
FE36_RS04305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FE36_RS04330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FE36_RS04335	COG0631	protein serine/threonine phosphatase activity
FE36_RS04350	COG0859	PFAM glycosyl transferase family 9
FE36_RS04355	COG3642	lipopolysaccharide core region biosynthetic process
FE36_RS04360	COG1234	tRNA 3'-trailer cleavage
FE36_RS04365	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FE36_RS04375	COG0315	cyclic pyranopterin monophosphate synthase activity
FE36_RS04380	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FE36_RS04385	COG0314	molybdopterin synthase activity
FE36_RS04400	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FE36_RS04410	COG0537	adenosine 5'-monophosphoramidase activity
FE36_RS04430	COG0714	Associated with various cellular activities
FE36_RS04450	COG1399	metal-binding, possibly nucleic acid-binding protein
FE36_RS04475	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_RS04480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FE36_RS04490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FE36_RS04495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FE36_RS04525	COG3829	transcription factor binding
FE36_RS04540	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FE36_RS04585	COG0678	peroxiredoxin activity
FE36_RS04605	COG0330	HflC and HflK could
FE36_RS04610	COG0330	HflC and HflK could
FE36_RS04625	COG0308	aminopeptidase N
FE36_RS04630	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_RS04635	COG1309	transcriptional regulator
FE36_RS04675	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FE36_RS04710	COG0732	type I restriction modification DNA specificity domain
FE36_RS04785	COG0587	DNA-directed DNA polymerase activity
FE36_RS04800	COG1297	OPT oligopeptide transporter protein
FE36_RS04810	COG1506	peptidase
FE36_RS04810	COG0823	Involved in the tonB-independent uptake of proteins
FE36_RS04820	COG2207	Transcriptional regulator
FE36_RS04820	COG1917	Cupin 2, conserved barrel domain protein
FE36_RS04835	COG0753	catalase activity
FE36_RS04870	COG3551	Protein conserved in bacteria
FE36_RS04905	COG2194	sulfuric ester hydrolase activity
FE36_RS04915	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FE36_RS04920	COG0745	RESPONSE REGULATOR receiver
FE36_RS04925	COG0642	Histidine kinase
FE36_RS04935	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FE36_RS04940	COG2894	cell division
FE36_RS04955	COG4585	Histidine kinase
FE36_RS04960	COG2197	response regulator
FE36_RS04975	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FE36_RS05000	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FE36_RS05005	COG2963	transposase activity
FE36_RS05200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FE36_RS05215	COG1842	Phage shock protein A
FE36_RS05240	COG0754	glutathionylspermidine amidase activity
FE36_RS05325	COG0531	amino acid
FE36_RS05330	COG2197	response regulator
FE36_RS05340	COG1113	amino acid transport
FE36_RS05345	COG1271	oxidase subunit
FE36_RS05350	COG1294	oxidase, subunit
FE36_RS05360	COG2239	Acts as a magnesium transporter
FE36_RS05365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FE36_RS05370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE36_RS05380	COG1660	Displays ATPase and GTPase activities
FE36_RS05390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE36_RS05405	COG1137	ATPase activity
FE36_RS05410	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FE36_RS05420	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FE36_RS05430	COG0271	Belongs to the BolA IbaG family
FE36_RS05435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FE36_RS05455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FE36_RS05470	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FE36_RS05480	COG0628	permease
FE36_RS05490	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FE36_RS05495	COG3178	'Phosphotransferase
FE36_RS05505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FE36_RS05510	COG1555	photosystem II stabilization
FE36_RS05525	COG2146	nitrite reductase [NAD(P)H] activity
FE36_RS05535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FE36_RS05540	COG0719	Fe-S assembly protein
FE36_RS05545	COG0396	ATPase activity
FE36_RS05550	COG0719	Fe-S assembly protein
FE36_RS05555	COG1959	2 iron, 2 sulfur cluster binding
FE36_RS05600	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FE36_RS05625	COG0519	Catalyzes the synthesis of GMP from XMP
FE36_RS05640	COG1678	Uncharacterized ACR, COG1678
FE36_RS05645	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FE36_RS05655	COG1764	response to oxidative stress
FE36_RS05665	COG0384	phenazine biosynthesis protein PhzF
FE36_RS05675	COG0527	aspartate kinase activity
FE36_RS05705	COG0142	geranyltranstransferase activity
FE36_RS05710	COG0629	single-stranded DNA binding
FE36_RS05715	COG5001	Diguanylate cyclase
FE36_RS05715	COG4251	negative regulation of phosphorylation
FE36_RS05715	COG3706	GGDEF domain
FE36_RS05715	COG2203	Gaf domain
FE36_RS05720	COG3321	synthase
FE36_RS05720	COG0604	alcohol dehydrogenase
FE36_RS05720	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_RS05730	COG2080	2 iron, 2 sulfur cluster binding
FE36_RS05735	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FE36_RS05740	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FE36_RS05770	COG2879	small protein
FE36_RS05775	COG1966	Carbon starvation protein
FE36_RS05780	COG1741	Belongs to the pirin family
FE36_RS05810	COG1741	Belongs to the pirin family
FE36_RS05815	COG1515	deoxyribonuclease V activity
FE36_RS05830	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FE36_RS05835	COG2200	EAL domain
FE36_RS05835	COG2199	diguanylate cyclase activity
FE36_RS05835	COG2202	Pas domain
FE36_RS05840	COG0835	chemotaxis
FE36_RS05845	COG0840	transmembrane signaling receptor activity
FE36_RS05850	COG0643	Histidine kinase
FE36_RS05850	COG2198	Histidine kinase
FE36_RS05860	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FE36_RS05870	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FE36_RS05905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FE36_RS05910	COG0735	belongs to the Fur family
FE36_RS05970	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FE36_RS06015	COG5001	Diguanylate cyclase
FE36_RS06015	COG5002	protein histidine kinase activity
FE36_RS06020	COG1187	pseudouridine synthase activity
FE36_RS06035	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FE36_RS06045	COG0475	glutathione-regulated potassium exporter activity
FE36_RS06050	COG5000	phosphorelay sensor kinase activity
FE36_RS06050	COG5002	protein histidine kinase activity
FE36_RS06055	COG0745	RESPONSE REGULATOR receiver
FE36_RS06085	COG1132	(ABC) transporter
FE36_RS06140	COG3118	belongs to the thioredoxin family
FE36_RS06165	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FE36_RS06190	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FE36_RS06205	COG2968	Membrane
FE36_RS06220	COG3164	Protein of unknown function
FE36_RS06230	COG0312	modulator of DNA gyrase
FE36_RS06235	COG3028	Belongs to the UPF0307 family
FE36_RS06240	COG0312	modulator of DNA gyrase
FE36_RS06260	COG4104	PAAR repeat-containing protein
FE36_RS06265	COG0142	geranyltranstransferase activity
FE36_RS06270	COG1722	exodeoxyribonuclease VII activity
FE36_RS06275	COG0037	tRNA processing
FE36_RS06280	COG1785	Belongs to the alkaline phosphatase family
FE36_RS06285	COG1301	dicarboxylic acid transport
FE36_RS06290	COG4106	trans-aconitate 2-methyltransferase activity
FE36_RS06300	COG0791	NLP P60 protein
FE36_RS06305	COG0791	NLP P60 protein
FE36_RS06310	COG1047	Peptidyl-prolyl cis-trans
FE36_RS06315	COG2311	Membrane
FE36_RS06320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE36_RS06350	COG3590	peptidase
FE36_RS06360	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FE36_RS06370	COG2914	Belongs to the UPF0125 (RnfH) family
FE36_RS06375	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE36_RS06385	COG0497	DNA recombination
FE36_RS06395	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FE36_RS06400	COG0443	Heat shock 70 kDa protein
FE36_RS06405	COG0484	heat shock protein binding
FE36_RS06410	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FE36_RS06420	COG0583	DNA-binding transcription factor activity
FE36_RS06425	COG1132	(ABC) transporter
FE36_RS06520	COG1131	(ABC) transporter
FE36_RS06525	COG1725	Transcriptional regulator
FE36_RS06535	COG0386	Belongs to the glutathione peroxidase family
FE36_RS06550	COG2900	Belongs to the SlyX family
FE36_RS06565	COG1609	Transcriptional regulator
FE36_RS06575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE36_RS06595	COG2226	methyltransferase
FE36_RS06600	COG1960	acyl-CoA dehydrogenase activity
FE36_RS06620	COG0557	exoribonuclease II activity
FE36_RS06630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FE36_RS06645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FE36_RS06655	COG0704	Plays a role in the regulation of phosphate uptake
FE36_RS06670	COG0573	inorganic phosphate transmembrane transporter activity
FE36_RS06675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FE36_RS06705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FE36_RS06715	COG1024	Enoyl-CoA hydratase
FE36_RS06725	COG0494	nUDIX hydrolase
FE36_RS06765	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FE36_RS06765	COG0116	Belongs to the methyltransferase superfamily
FE36_RS06785	COG0667	Aldo Keto reductase
FE36_RS06795	COG2925	Exonuclease
FE36_RS06805	COG3844	kynureninase activity
FE36_RS06820	COG0288	reversible hydration of carbon dioxide
FE36_RS06850	COG0316	Belongs to the HesB IscA family
FE36_RS06855	COG0360	Binds together with S18 to 16S ribosomal RNA
FE36_RS06875	COG3115	cell septum assembly
FE36_RS06890	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FE36_RS06900	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FE36_RS06915	COG2963	transposase activity
FE36_RS06925	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FE36_RS06940	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FE36_RS06995	COG0438	transferase activity, transferring glycosyl groups
FE36_RS07000	COG0438	transferase activity, transferring glycosyl groups
FE36_RS07010	COG0438	transferase activity, transferring glycosyl groups
FE36_RS07040	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FE36_RS07050	COG1960	acyl-CoA dehydrogenase activity
FE36_RS07060	COG3040	lipid binding
FE36_RS07085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FE36_RS07090	COG0784	Response regulator, receiver
FE36_RS07090	COG4191	Histidine kinase
FE36_RS07100	COG1194	a g-specific adenine glycosylase
FE36_RS07110	COG0552	protein localization to endoplasmic reticulum
FE36_RS07120	COG3938	Belongs to the proline racemase family
FE36_RS07125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE36_RS07140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE36_RS07150	COG0006	proline dipeptidase activity
FE36_RS07165	COG0531	amino acid
FE36_RS07215	COG4206	TonB-dependent receptor
FE36_RS07255	COG0326	Molecular chaperone. Has ATPase activity
FE36_RS07260	COG0742	ribosomal rna small subunit methyltransferase
FE36_RS07265	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FE36_RS07280	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FE36_RS07285	COG0405	Gamma-glutamyltransferase
FE36_RS07335	COG0343	queuine tRNA-ribosyltransferase activity
FE36_RS07340	COG1862	Preprotein translocase
FE36_RS07350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE36_RS07390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE36_RS07390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE36_RS07395	COG1105	Belongs to the carbohydrate kinase PfkB family
FE36_RS07400	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE36_RS07400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FE36_RS07405	COG1609	Transcriptional regulator
FE36_RS07415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE36_RS07420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE36_RS07430	COG2902	Dehydrogenase
FE36_RS07440	COG0477	Major facilitator Superfamily
FE36_RS07450	COG5002	protein histidine kinase activity
FE36_RS07450	COG0784	Response regulator, receiver
FE36_RS07450	COG2205	protein histidine kinase activity
FE36_RS07455	COG2733	membrane
FE36_RS07465	COG1121	(ABC) transporter
FE36_RS07470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FE36_RS07485	COG0243	molybdopterin cofactor binding
FE36_RS07490	COG0477	Major facilitator Superfamily
FE36_RS07500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE36_RS07505	COG0174	glutamine synthetase
FE36_RS07510	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FE36_RS07525	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FE36_RS07545	COG3842	ATPase activity
FE36_RS07550	COG1176	ABC-type spermidine putrescine transport system, permease component I
FE36_RS07555	COG1177	transmembrane transport
FE36_RS07560	COG1012	belongs to the aldehyde dehydrogenase family
FE36_RS07575	COG4535	Mg2 and Co2 transporter CorC
FE36_RS07595	COG1702	phosphate starvation-inducible protein PhoH
FE36_RS07615	COG0741	lytic transglycosylase activity
FE36_RS07625	COG0723	plastoquinol--plastocyanin reductase activity
FE36_RS07630	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FE36_RS07635	COG2857	Cytochrome c1
FE36_RS07640	COG0625	glutathione transferase activity
FE36_RS07645	COG2969	positive regulation of protein catabolic process
FE36_RS07670	COG0840	transmembrane signaling receptor activity
FE36_RS07675	COG0835	chemotaxis
FE36_RS07685	COG2801	Transposase and inactivated derivatives
FE36_RS07785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FE36_RS07840	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FE36_RS07855	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FE36_RS07860	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FE36_RS07860	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FE36_RS07865	COG0802	atpase or kinase
FE36_RS07870	COG0860	N-Acetylmuramoyl-L-alanine amidase
FE36_RS07875	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FE36_RS07895	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_RS07915	COG2081	HI0933 family
FE36_RS07920	COG4681	YaeQ
FE36_RS07925	COG1671	Belongs to the UPF0178 family
FE36_RS07930	COG1278	Cold shock
FE36_RS07935	COG0625	glutathione transferase activity
FE36_RS07945	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FE36_RS07955	COG0513	Belongs to the DEAD box helicase family
FE36_RS07960	COG0488	(ABC) transporter
FE36_RS07980	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FE36_RS07985	COG0483	inositol monophosphate 1-phosphatase activity
FE36_RS08000	COG5001	Diguanylate cyclase
FE36_RS08000	COG3300	MHYT domain
FE36_RS08005	COG1509	lysine 2,3-aminomutase activity
FE36_RS08020	COG0402	S-adenosylhomocysteine deaminase activity
FE36_RS08025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FE36_RS08055	COG1741	Belongs to the pirin family
FE36_RS08060	COG0583	DNA-binding transcription factor activity
FE36_RS08085	COG0352	thiamine-phosphate diphosphorylase activity
FE36_RS08085	COG0351	phosphomethylpyrimidine kinase
FE36_RS08095	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FE36_RS08100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FE36_RS08115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE36_RS08125	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FE36_RS08130	COG3734	2-keto-3-deoxy-galactonokinase
FE36_RS08140	COG4948	Mandelate Racemase Muconate Lactonizing
FE36_RS08145	COG0800	Aldolase
FE36_RS08170	COG1070	Carbohydrate kinase
FE36_RS08180	COG0477	Major facilitator Superfamily
FE36_RS08185	COG0860	N-Acetylmuramoyl-L-alanine amidase
FE36_RS08190	COG1469	GTP cyclohydrolase I activity
FE36_RS08200	COG0617	tRNA 3'-terminal CCA addition
FE36_RS08220	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FE36_RS08245	COG1472	Belongs to the glycosyl hydrolase 3 family
FE36_RS08255	COG3706	GGDEF domain
FE36_RS08255	COG2203	Gaf domain
FE36_RS08255	COG5001	Diguanylate cyclase
FE36_RS08255	COG4251	negative regulation of phosphorylation
FE36_RS08260	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FE36_RS08265	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FE36_RS08280	COG0671	phosphoesterase, PA-phosphatase related
FE36_RS08290	COG0697	spore germination
FE36_RS08295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FE36_RS08315	COG1012	belongs to the aldehyde dehydrogenase family
FE36_RS08360	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FE36_RS08375	COG0124	histidyl-tRNA synthetase
FE36_RS08385	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FE36_RS08400	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FE36_RS08400	COG0131	Imidazoleglycerol-phosphate dehydratase
FE36_RS08410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FE36_RS08420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FE36_RS08420	COG0140	phosphoribosyl-ATP diphosphatase activity
FE36_RS08440	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FE36_RS08445	COG0235	Class ii aldolase
FE36_RS08450	COG0531	amino acid
FE36_RS08455	COG0531	amino acid
FE36_RS08465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FE36_RS08470	COG0277	FAD linked oxidase domain protein
FE36_RS08490	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FE36_RS08535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE36_RS08540	COG2258	MOSC domain
FE36_RS08545	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FE36_RS08550	COG0505	Belongs to the CarA family
FE36_RS08560	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FE36_RS08565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FE36_RS08575	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FE36_RS08590	COG3279	Response regulator of the LytR AlgR family
FE36_RS08595	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FE36_RS08610	COG2205	protein histidine kinase activity
FE36_RS08610	COG2198	Histidine kinase
FE36_RS08610	COG0784	Response regulator, receiver
FE36_RS08615	COG1024	Enoyl-CoA hydratase
FE36_RS08620	COG0318	PFAM AMP-dependent synthetase and ligase
FE36_RS08650	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FE36_RS08685	COG0835	chemotaxis
FE36_RS08695	COG0840	transmembrane signaling receptor activity
FE36_RS08710	COG0840	transmembrane signaling receptor activity
FE36_RS08720	COG0840	transmembrane signaling receptor activity
FE36_RS08730	COG0840	transmembrane signaling receptor activity
FE36_RS08740	COG0840	transmembrane signaling receptor activity
FE36_RS08750	COG0745	RESPONSE REGULATOR receiver
FE36_RS08760	COG0835	chemotaxis
FE36_RS08765	COG1192	Involved in chromosome partitioning
FE36_RS08770	COG1360	Flagellar Motor Protein
FE36_RS08775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FE36_RS08790	COG4774	siderophore transport
FE36_RS08795	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FE36_RS08820	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FE36_RS08855	COG0643	Histidine kinase
FE36_RS08855	COG0784	Response regulator, receiver
FE36_RS08855	COG2198	Histidine kinase
FE36_RS08910	COG1684	flagellar biosynthetic protein fliR
FE36_RS08930	COG3190	flagellar
FE36_RS08980	COG1677	Flagellar hook-basal body complex protein FliE
FE36_RS09005	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_RS09010	COG4221	oxidoreductase activity
FE36_RS09015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FE36_RS09035	COG2201	protein-glutamate methylesterase activity
FE36_RS09065	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FE36_RS09070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FE36_RS09085	COG1705	Flagellar rod assembly protein muramidase FlgJ
FE36_RS09085	COG3951	Flagellar rod assembly protein muramidase FlgJ
FE36_RS09105	COG4787	bacterial-type flagellum-dependent cell motility
FE36_RS09115	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FE36_RS09120	COG1558	bacterial-type flagellum-dependent cell motility
FE36_RS09130	COG0784	Response regulator, receiver
FE36_RS09130	COG0835	chemotaxis
FE36_RS09150	COG4191	Histidine kinase
FE36_RS09160	COG4585	Histidine kinase
FE36_RS09195	COG0482	sulfurtransferase activity
FE36_RS09210	COG0542	response to heat
FE36_RS09240	COG0492	ferredoxin-NADP+ reductase activity
FE36_RS09245	COG1674	ftsk spoiiie
FE36_RS09265	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FE36_RS09285	COG0038	chloride channel
FE36_RS09290	COG0183	Belongs to the thiolase family
FE36_RS09295	COG1024	Enoyl-CoA hydratase
FE36_RS09295	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE36_RS09310	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FE36_RS09330	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE36_RS09335	COG1160	GTP binding
FE36_RS09340	COG0303	'Molybdopterin
FE36_RS09345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FE36_RS09370	COG0746	molybdenum cofactor guanylyltransferase activity
FE36_RS09395	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FE36_RS09395	COG1648	precorrin-2 dehydrogenase activity
FE36_RS09435	COG5001	Diguanylate cyclase
FE36_RS09445	COG4566	intracellular signal transduction
FE36_RS09525	COG3328	transposase activity
FE36_RS09535	COG3039	Transposase
FE36_RS09600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE36_RS09605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE36_RS09640	COG2963	transposase activity
FE36_RS09670	COG1858	cytochrome C peroxidase
FE36_RS09695	COG0515	serine threonine protein kinase
FE36_RS09700	COG0631	protein serine/threonine phosphatase activity
FE36_RS09745	COG3039	Transposase
FE36_RS09830	COG2154	pterin-4-alpha-carbinolamine dehydratase
FE36_RS09845	COG3064	Membrane
FE36_RS09855	COG1530	ribonuclease E activity
FE36_RS09865	COG1054	Belongs to the UPF0176 family
FE36_RS09885	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FE36_RS09900	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FE36_RS09900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FE36_RS09915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FE36_RS09945	COG0322	excinuclease ABC activity
FE36_RS09955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FE36_RS09965	COG1663	tetraacyldisaccharide 4'-kinase activity
FE36_RS09980	COG0811	peptide transport
FE36_RS10005	COG4591	ABC-type transport system involved in lipoprotein release permease component
FE36_RS10020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FE36_RS10035	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FE36_RS10045	COG0354	folic acid binding
FE36_RS10055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FE36_RS10065	COG0363	glucosamine-6-phosphate deaminase activity
FE36_RS10070	COG0129	dihydroxy-acid dehydratase activity
FE36_RS10075	COG0800	Aldolase
FE36_RS10170	COG0784	Response regulator, receiver
FE36_RS10170	COG2205	protein histidine kinase activity
FE36_RS10175	COG2183	response to ionizing radiation
FE36_RS10185	COG0723	plastoquinol--plastocyanin reductase activity
FE36_RS10185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE36_RS10200	COG3243	poly(R)-hydroxyalkanoic acid synthase
FE36_RS10210	COG1183	phosphatidylcholine synthase activity
FE36_RS10215	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_RS10240	COG0668	transmembrane transport
FE36_RS10260	COG1914	H( )-stimulated, divalent metal cation uptake system
FE36_RS10280	COG0583	DNA-binding transcription factor activity
FE36_RS10285	COG0583	DNA-binding transcription factor activity
FE36_RS10305	COG0583	DNA-binding transcription factor activity
FE36_RS10310	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FE36_RS10315	COG3002	Belongs to the UPF0753 family
FE36_RS10320	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FE36_RS10320	COG0519	Catalyzes the synthesis of GMP from XMP
FE36_RS10330	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FE36_RS10345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FE36_RS10355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FE36_RS10360	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FE36_RS10370	COG0776	regulation of translation
FE36_RS10375	COG0539	negative regulation of cytoplasmic translation
FE36_RS10380	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FE36_RS10395	COG2957	Belongs to the agmatine deiminase family
FE36_RS10400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE36_RS10420	COG0395	ABC-type sugar transport system, permease component
FE36_RS10425	COG1175	transmembrane transport
FE36_RS10455	COG2350	Protein conserved in bacteria
FE36_RS10460	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FE36_RS10465	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FE36_RS10470	COG1187	pseudouridine synthase activity
FE36_RS10490	COG0436	Aminotransferase
FE36_RS10495	COG4133	protoheme IX ABC transporter activity
FE36_RS10555	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FE36_RS10560	COG4988	ABC transporter
FE36_RS10570	COG1271	oxidase subunit
FE36_RS10575	COG1294	oxidase, subunit
FE36_RS10620	COG0165	Argininosuccinate lyase
FE36_RS10635	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FE36_RS10640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FE36_RS10650	COG0137	argininosuccinate synthase activity
FE36_RS10655	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FE36_RS10670	COG2166	iron-sulfur cluster assembly
FE36_RS10700	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FE36_RS10725	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FE36_RS10740	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FE36_RS10745	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FE36_RS10750	COG2137	regulation of response to DNA damage stimulus
FE36_RS10755	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FE36_RS10770	COG1546	Belongs to the CinA family
FE36_RS10775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FE36_RS10790	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FE36_RS10800	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FE36_RS10805	COG1534	Rna-binding protein
FE36_RS10820	COG1238	metal cluster binding
FE36_RS10825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FE36_RS10830	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FE36_RS10845	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FE36_RS10855	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FE36_RS10860	COG0148	phosphopyruvate hydratase activity
FE36_RS10870	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FE36_RS10875	COG0504	CTP synthase activity
FE36_RS10910	COG1253	flavin adenine dinucleotide binding
FE36_RS10925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE36_RS10930	COG2271	Major facilitator Superfamily
FE36_RS10935	COG1132	(ABC) transporter
FE36_RS10955	COG0438	transferase activity, transferring glycosyl groups
FE36_RS10965	COG2264	protein methyltransferase activity
FE36_RS10995	COG2244	polysaccharide biosynthetic process
FE36_RS11045	COG1595	DNA-templated transcription, initiation
FE36_RS11060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE36_RS11080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FE36_RS11100	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FE36_RS11105	COG0784	Response regulator, receiver
FE36_RS11105	COG5002	protein histidine kinase activity
FE36_RS11105	COG2205	protein histidine kinase activity
FE36_RS11120	COG0840	transmembrane signaling receptor activity
FE36_RS11160	COG0583	DNA-binding transcription factor activity
FE36_RS11165	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FE36_RS11170	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FE36_RS11185	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FE36_RS11190	COG0077	Prephenate dehydratase
FE36_RS11190	COG1605	Chorismate mutase
FE36_RS11195	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FE36_RS11200	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FE36_RS11240	COG1228	amidohydrolase
FE36_RS11245	COG2986	histidine ammonia-lyase
FE36_RS11255	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FE36_RS11275	COG0556	nucleotide-excision repair
FE36_RS11280	COG4969	Belongs to the N-Me-Phe pilin family
FE36_RS11285	COG4974	Belongs to the 'phage' integrase family
FE36_RS11375	COG4695	Portal protein
FE36_RS11420	COG3179	chitinase
FE36_RS11620	COG1611	Belongs to the LOG family
FE36_RS11630	COG2095	MarC family integral membrane protein
FE36_RS11640	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FE36_RS11675	COG1185	polyribonucleotide nucleotidyltransferase activity
FE36_RS11680	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FE36_RS11695	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FE36_RS11700	COG0195	Participates in both transcription termination and antitermination
FE36_RS11705	COG0779	Required for maturation of 30S ribosomal subunits
FE36_RS11715	COG1007	ATP synthesis coupled electron transport
FE36_RS11745	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FE36_RS11750	COG1034	ATP synthesis coupled electron transport
FE36_RS11755	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FE36_RS11760	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FE36_RS11765	COG0649	NAD binding
FE36_RS11770	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE36_RS11780	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE36_RS11795	COG0149	triose-phosphate isomerase activity
FE36_RS11830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FE36_RS11835	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FE36_RS11850	COG0133	tryptophan synthase activity
FE36_RS11860	COG0135	phosphoribosylanthranilate isomerase activity
FE36_RS11865	COG0101	tRNA pseudouridine synthase activity
FE36_RS11880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FE36_RS11885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FE36_RS11890	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FE36_RS11895	COG2890	protein-(glutamine-N5) methyltransferase activity
FE36_RS11915	COG0433	COG0433 Predicted ATPase
FE36_RS11930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FE36_RS11935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FE36_RS11960	COG0717	Belongs to the dCTP deaminase family
FE36_RS11965	COG0489	protein tyrosine kinase activity
FE36_RS11975	COG3706	GGDEF domain
FE36_RS11995	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_RS12010	COG0415	Belongs to the DNA photolyase family
FE36_RS12015	COG0305	Participates in initiation and elongation during chromosome replication
FE36_RS12025	COG0367	asparagine synthase
FE36_RS12040	COG1960	acyl-CoA dehydrogenase activity
FE36_RS12055	COG0084	hydrolase, TatD family'
FE36_RS12060	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FE36_RS12115	COG0386	Belongs to the glutathione peroxidase family
FE36_RS12205	COG2814	Major facilitator Superfamily
FE36_RS12210	COG1566	PFAM secretion protein HlyD family protein
FE36_RS12225	COG2207	Transcriptional regulator
FE36_RS12245	COG4774	siderophore transport
FE36_RS12255	COG0367	asparagine synthase
FE36_RS12260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FE36_RS12270	COG1393	Belongs to the ArsC family
FE36_RS12330	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FE36_RS12345	COG0233	cytoplasmic translational termination
FE36_RS12355	COG0575	Belongs to the CDS family
FE36_RS12360	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FE36_RS12365	COG0750	zinc metalloprotease
FE36_RS12375	COG3039	Transposase
FE36_RS12380	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE36_RS12385	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FE36_RS12390	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE36_RS12410	COG0825	malonyl-CoA metabolic process
FE36_RS12425	COG1981	membrane
FE36_RS12445	COG1695	Transcriptional regulator
FE36_RS12465	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FE36_RS12475	COG2040	homocysteine
FE36_RS12480	COG0833	amino acid
FE36_RS12485	COG0346	lactoylglutathione lyase activity
FE36_RS12495	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE36_RS12495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE36_RS12505	COG2878	Part of a membrane complex involved in electron transport
FE36_RS12525	COG1595	DNA-templated transcription, initiation
FE36_RS12550	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FE36_RS12565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FE36_RS12570	COG0251	oxidation-reduction process
FE36_RS12580	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FE36_RS12580	COG0392	lysyltransferase activity
FE36_RS12610	COG2814	Major facilitator Superfamily
FE36_RS12615	COG1902	pentaerythritol trinitrate reductase activity
FE36_RS12625	COG2824	Alkylphosphonate utilization operon protein PhnA
FE36_RS12635	COG1047	Peptidyl-prolyl cis-trans
FE36_RS12670	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FE36_RS12690	COG1451	nucleotide metabolic process
FE36_RS12705	COG0183	Belongs to the thiolase family
FE36_RS12720	COG3706	GGDEF domain
FE36_RS12735	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FE36_RS12735	COG1793	dna ligase
FE36_RS12745	COG1793	dna ligase
FE36_RS12750	COG1201	RNA secondary structure unwinding
FE36_RS12765	COG1278	Cold shock
FE36_RS12770	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FE36_RS12775	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FE36_RS12785	COG3046	protein related to deoxyribodipyrimidine photolyase
FE36_RS12790	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
FE36_RS12795	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FE36_RS12800	COG2954	triphosphatase activity
FE36_RS12815	COG1381	Involved in DNA repair and RecF pathway recombination
FE36_RS12835	COG0681	Belongs to the peptidase S26 family
FE36_RS12840	COG0481	GTPase activity
FE36_RS12845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE36_RS12860	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE36_RS12860	COG1024	Enoyl-CoA hydratase
FE36_RS12885	COG1960	acyl-CoA dehydrogenase activity
FE36_RS12910	COG3250	beta-galactosidase activity
FE36_RS12945	COG0784	Response regulator, receiver
FE36_RS12945	COG5002	protein histidine kinase activity
FE36_RS12950	COG0784	Response regulator, receiver
FE36_RS12950	COG2205	protein histidine kinase activity
FE36_RS12950	COG2198	Histidine kinase
FE36_RS12955	COG2353	YceI-like domain
FE36_RS12985	COG1760	l-serine dehydratase
FE36_RS12995	COG0626	cystathionine gamma-synthase activity
FE36_RS13000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FE36_RS13005	COG0739	heme binding
FE36_RS13015	COG1272	protein, Hemolysin III
FE36_RS13025	COG0516	GMP reductase activity
FE36_RS13025	COG0517	IMP dehydrogenase activity
FE36_RS13030	COG0463	Glycosyl transferase, family 2
FE36_RS13040	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FE36_RS13050	COG4771	TonB-dependent receptor
FE36_RS13055	COG1309	transcriptional regulator
FE36_RS13065	COG1960	acyl-CoA dehydrogenase activity
FE36_RS13095	COG0509	glycine decarboxylation via glycine cleavage system
FE36_RS13110	COG0330	HflC and HflK could
FE36_RS13115	COG1742	UPF0060 membrane protein
FE36_RS13120	COG3956	TIGRFAM MazG family protein
FE36_RS13130	COG0494	nUDIX hydrolase
FE36_RS13140	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FE36_RS13145	COG0837	glucose binding
FE36_RS13160	COG3858	chitin binding
FE36_RS13160	COG1388	LysM domain
FE36_RS13165	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE36_RS13175	COG1472	Belongs to the glycosyl hydrolase 3 family
FE36_RS13190	COG3537	Alpha-1,2-mannosidase
FE36_RS13235	COG1446	asparaginase
FE36_RS13240	COG2304	oxidoreductase activity
FE36_RS13265	COG0643	Histidine kinase
FE36_RS13265	COG0784	Response regulator, receiver
FE36_RS13265	COG2198	Histidine kinase
FE36_RS13270	COG0840	transmembrane signaling receptor activity
FE36_RS13275	COG0835	chemotaxis
FE36_RS13290	COG0189	ligase activity
FE36_RS13310	COG1199	ATP-dependent helicase activity
FE36_RS13320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FE36_RS13325	COG1215	transferase activity, transferring glycosyl groups
FE36_RS13335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FE36_RS13385	COG1643	Atp-dependent helicase
FE36_RS13390	COG0783	Belongs to the Dps family
FE36_RS13395	COG0514	ATP-dependent DNA helicase (RecQ)
FE36_RS13410	COG1187	pseudouridine synthase activity
FE36_RS13420	COG0840	transmembrane signaling receptor activity
FE36_RS13430	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FE36_RS13440	COG0602	queuosine metabolic process
FE36_RS13450	COG2885	chlorophyll binding
FE36_RS13455	COG0823	Involved in the tonB-independent uptake of proteins
FE36_RS13475	COG0824	Thioesterase
FE36_RS13480	COG2255	four-way junction helicase activity
FE36_RS13515	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FE36_RS13530	COG0477	Major facilitator Superfamily
FE36_RS13545	COG0657	acetylesterase activity
FE36_RS13545	COG2755	lipolytic protein G-D-S-L family
FE36_RS13565	COG0488	(ABC) transporter
FE36_RS13595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FE36_RS13595	COG4651	solute:proton antiporter activity
FE36_RS13605	COG4772	TonB-dependent receptor
FE36_RS13615	COG4264	IucA IucC family
FE36_RS13620	COG2814	Major facilitator Superfamily
FE36_RS13630	COG0019	diaminopimelate decarboxylase activity
FE36_RS13665	COG0542	response to heat
FE36_RS13690	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FE36_RS13700	COG0534	Mate efflux family protein
FE36_RS13710	COG0336	Belongs to the RNA methyltransferase TrmD family
FE36_RS13715	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FE36_RS13720	COG0228	four-way junction DNA binding
FE36_RS13730	COG2070	2-Nitropropane dioxygenase
FE36_RS13745	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FE36_RS13750	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE36_RS13785	COG2172	sigma factor antagonist activity
FE36_RS13790	COG1366	Belongs to the anti-sigma-factor antagonist family
FE36_RS13795	COG1366	Belongs to the anti-sigma-factor antagonist family
FE36_RS13810	COG0326	Molecular chaperone. Has ATPase activity
FE36_RS13815	COG2207	Transcriptional regulator
FE36_RS13860	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FE36_RS13865	COG1845	cytochrome c oxidase, subunit III
FE36_RS13870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FE36_RS13885	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FE36_RS13890	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FE36_RS13905	COG0728	peptidoglycan biosynthetic process
FE36_RS13910	COG0268	Binds directly to 16S ribosomal RNA
FE36_RS13915	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FE36_RS13920	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FE36_RS13930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FE36_RS13935	COG0824	Thioesterase
FE36_RS13950	COG1946	Acyl-CoA thioesterase
FE36_RS13960	COG1595	DNA-templated transcription, initiation
FE36_RS13975	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FE36_RS14015	COG1877	trehalose-phosphatase activity
FE36_RS14020	COG3387	PFAM Glycoside hydrolase 15-related
FE36_RS14035	COG0840	transmembrane signaling receptor activity
FE36_RS14040	COG3011	Protein conserved in bacteria
FE36_RS14055	COG0564	pseudouridine synthase activity
FE36_RS14060	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE36_RS14065	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FE36_RS14065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE36_RS14075	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FE36_RS14080	COG0045	succinate-CoA ligase (ADP-forming) activity
FE36_RS14095	COG2184	nucleotidyltransferase activity
FE36_RS14115	COG2194	sulfuric ester hydrolase activity
FE36_RS14120	COG4969	Belongs to the N-Me-Phe pilin family
FE36_RS14130	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FE36_RS14150	COG0745	RESPONSE REGULATOR receiver
FE36_RS14200	COG2022	thiamine diphosphate biosynthetic process
FE36_RS14210	COG0471	metal ion transport
FE36_RS14210	COG3273	potassium ion transport
FE36_RS14230	COG1970	mechanosensitive ion channel activity
FE36_RS14235	COG3328	transposase activity
FE36_RS14245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FE36_RS14265	COG0308	aminopeptidase N
FE36_RS14270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE36_RS14280	COG0529	Catalyzes the synthesis of activated sulfate
FE36_RS14280	COG2895	sulfate adenylyltransferase (ATP) activity
FE36_RS14285	COG0175	sulfate reduction
FE36_RS14290	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FE36_RS14295	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE36_RS14300	COG0175	sulfate reduction
FE36_RS14320	COG2205	protein histidine kinase activity
FE36_RS14320	COG2198	Histidine kinase
FE36_RS14320	COG0784	Response regulator, receiver
FE36_RS14335	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FE36_RS14335	COG1648	precorrin-2 dehydrogenase activity
FE36_RS14355	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FE36_RS14360	COG3588	fructose-bisphosphate aldolase
FE36_RS14365	COG0469	pyruvate kinase activity
FE36_RS14375	COG0126	phosphoglycerate kinase activity
FE36_RS14390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FE36_RS14405	COG3453	Protein conserved in bacteria
FE36_RS14405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE36_RS14410	COG0725	ABC transporter, periplasmic molybdate-binding protein
FE36_RS14415	COG4149	molybdate abc transporter
FE36_RS14420	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FE36_RS14465	COG1022	Amp-dependent synthetase and ligase
FE36_RS14505	COG1376	ErfK ybiS ycfS ynhG family protein
FE36_RS14515	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FE36_RS14520	COG1301	dicarboxylic acid transport
FE36_RS14535	COG2304	oxidoreductase activity
FE36_RS14555	COG0714	Associated with various cellular activities
FE36_RS14585	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FE36_RS14610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FE36_RS14620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FE36_RS14635	COG1561	YicC-like family, N-terminal region
FE36_RS14640	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FE36_RS14645	COG0346	lactoylglutathione lyase activity
FE36_RS14655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FE36_RS14680	COG0006	proline dipeptidase activity
FE36_RS14700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FE36_RS14720	COG2912	Transglutaminase-like superfamily
FE36_RS14725	COG1773	rubredoxin
FE36_RS14730	COG0352	thiamine-phosphate diphosphorylase activity
FE36_RS14740	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FE36_RS14765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FE36_RS14800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FE36_RS14805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FE36_RS14825	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_RS14840	COG3781	membrane
FE36_RS14850	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FE36_RS14870	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FE36_RS14880	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FE36_RS14900	COG3710	Transcriptional regulator
FE36_RS14905	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FE36_RS14910	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FE36_RS14940	COG2226	methyltransferase
FE36_RS14945	COG0066	3-isopropylmalate dehydratase activity
FE36_RS14950	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FE36_RS14975	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FE36_RS14980	COG1538	Outer membrane efflux protein
FE36_RS14985	COG1519	Transferase
FE36_RS14990	COG1560	Kdo2-lipid A biosynthetic process
FE36_RS15020	COG0280	phosphate acetyltransferase
FE36_RS15020	COG0281	malic enzyme
FE36_RS15035	COG4191	Histidine kinase
FE36_RS15050	COG0583	DNA-binding transcription factor activity
FE36_RS15075	COG2197	response regulator
FE36_RS15085	COG0642	Histidine kinase
FE36_RS15100	COG2851	Citrate transporter
FE36_RS15105	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_RS15110	COG1609	Transcriptional regulator
FE36_RS15115	COG2211	Major facilitator Superfamily
FE36_RS15145	COG0436	Aminotransferase
FE36_RS15160	COG0726	polysaccharide deacetylase
FE36_RS15165	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FE36_RS15185	COG3964	amidohydrolase
FE36_RS15190	COG1228	amidohydrolase
FE36_RS15205	COG0242	peptide deformylase activity
FE36_RS15220	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FE36_RS15265	COG2188	Transcriptional regulator
FE36_RS15280	COG1450	Type ii and iii secretion system protein
FE36_RS15295	COG3166	PFAM Fimbrial assembly family protein
FE36_RS15300	COG3156	type II secretion system protein K
FE36_RS15305	COG4795	General secretion pathway protein
FE36_RS15310	COG2165	general secretion pathway protein
FE36_RS15315	COG4970	Tfp pilus assembly protein FimT
FE36_RS15320	COG2165	general secretion pathway protein
FE36_RS15325	COG1459	type II secretion system
FE36_RS15330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FE36_RS15335	COG1404	Belongs to the peptidase S8 family
FE36_RS15340	COG5295	Hep Hag repeat protein
FE36_RS15345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FE36_RS15345	COG0047	phosphoribosylformylglycinamidine synthase activity
FE36_RS15350	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FE36_RS15355	COG4974	Belongs to the 'phage' integrase family
FE36_RS15370	COG0795	lipopolysaccharide-transporting ATPase activity
FE36_RS15380	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FE36_RS15395	COG0525	valine-tRNA ligase activity
FE36_RS15420	COG1183	phosphatidylcholine synthase activity
FE36_RS15430	COG0442	prolyl-tRNA aminoacylation
FE36_RS15445	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FE36_RS15450	COG1127	ABC transporter
FE36_RS15455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FE36_RS15455	COG3218	ABC-type transport auxiliary lipoprotein component
FE36_RS15490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FE36_RS15495	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FE36_RS15495	COG0662	Cupin 2, conserved barrel domain protein
FE36_RS15520	COG2086	electron transfer activity
FE36_RS15535	COG0546	phosphoglycolate phosphatase activity
FE36_RS15535	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FE36_RS15540	COG0277	FAD linked oxidase domain protein
FE36_RS15555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE36_RS15585	COG3754	Rhamnan synthesis protein F
FE36_RS15590	COG1216	Glycosyl transferase, family 2
FE36_RS15590	COG0438	transferase activity, transferring glycosyl groups
FE36_RS15595	COG0110	maltose O-acetyltransferase activity
FE36_RS15610	COG0626	cystathionine gamma-synthase activity
FE36_RS15645	COG0625	glutathione transferase activity
FE36_RS15655	COG0513	Belongs to the DEAD box helicase family
FE36_RS15660	COG0720	synthase
FE36_RS15670	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FE36_RS15675	COG1956	GAF domain-containing protein
FE36_RS15685	COG0546	phosphoglycolate phosphatase activity
FE36_RS15710	COG0339	signal peptide processing
FE36_RS15750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FE36_RS15755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE36_RS15760	COG1136	(ABC) transporter
FE36_RS15775	COG0577	efflux transmembrane transporter activity
FE36_RS15775	COG1136	(ABC) transporter
FE36_RS15780	COG0577	efflux transmembrane transporter activity
FE36_RS15780	COG1136	(ABC) transporter
FE36_RS15790	COG4191	Histidine kinase
FE36_RS15815	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FE36_RS15820	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FE36_RS15825	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FE36_RS15835	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FE36_RS15845	COG0356	it plays a direct role in the translocation of protons across the membrane
FE36_RS15865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE36_RS15875	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE36_RS15910	COG2011	ABC-type metal ion transport system permease component
FE36_RS15920	COG0697	spore germination
FE36_RS15950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FE36_RS15955	COG1187	pseudouridine synthase activity
FE36_RS15960	COG2813	Specifically methylates the guanine in position
FE36_RS15985	COG2202	Pas domain
FE36_RS15985	COG2205	protein histidine kinase activity
FE36_RS16010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE36_RS16055	COG0745	RESPONSE REGULATOR receiver
FE36_RS16070	COG1404	Belongs to the peptidase S8 family
FE36_RS16085	COG0842	Transport permease protein
FE36_RS16090	COG1131	(ABC) transporter
FE36_RS16095	COG0025	NhaP-type Na H and K H
FE36_RS16100	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FE36_RS16105	COG1573	uracil-dna glycosylase
FE36_RS16115	COG3384	dioxygenase
FE36_RS16130	COG0667	Aldo Keto reductase
FE36_RS16145	COG3590	peptidase
FE36_RS16160	COG0531	amino acid
FE36_RS16175	COG2972	Histidine kinase
FE36_RS16215	COG1271	oxidase subunit
FE36_RS16220	COG1294	oxidase, subunit
FE36_RS16235	COG1063	alcohol dehydrogenase
FE36_RS16310	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FE36_RS16345	COG2353	YceI-like domain
FE36_RS16375	COG2831	hemolysin activation secretion protein
FE36_RS16385	COG2951	lytic endotransglycosylase activity
FE36_RS16400	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FE36_RS16410	COG0842	Transport permease protein
FE36_RS16415	COG1131	(ABC) transporter
FE36_RS16420	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FE36_RS16440	COG1476	TRANSCRIPTIONal
FE36_RS16450	COG4555	ABC transporter
FE36_RS16485	COG0625	glutathione transferase activity
FE36_RS16510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FE36_RS16520	COG1560	Kdo2-lipid A biosynthetic process
FE36_RS16565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FE36_RS16565	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FE36_RS16570	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FE36_RS16575	COG0242	peptide deformylase activity
FE36_RS16580	COG1652	LysM domain
FE36_RS16585	COG0758	DNA mediated transformation
FE36_RS16605	COG1754	DNA topoisomerase type I activity
FE36_RS16605	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FE36_RS16610	COG0009	L-threonylcarbamoyladenylate synthase
FE36_RS16625	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_RS16635	COG0616	signal peptide processing
FE36_RS16640	COG0534	Mate efflux family protein
FE36_RS16660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FE36_RS16665	COG1324	tolerance protein
FE36_RS16680	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FE36_RS16685	COG0511	ligase activity, forming carbon-carbon bonds
FE36_RS16695	COG0439	Biotin carboxylase
FE36_RS16730	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FE36_RS16755	COG0138	bifunctional purine biosynthesis protein purh
FE36_RS16760	COG0151	Belongs to the GarS family
FE36_RS16765	COG1136	(ABC) transporter
FE36_RS16765	COG0577	efflux transmembrane transporter activity
FE36_RS16775	COG1289	transmembrane transporter activity
FE36_RS16790	COG2814	Major facilitator Superfamily
FE36_RS16805	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FE36_RS16875	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FE36_RS16885	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FE36_RS16895	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FE36_RS16900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FE36_RS16910	COG0134	indole-3-glycerol-phosphate synthase activity
FE36_RS16915	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FE36_RS16955	COG0456	acetyltransferase
FE36_RS16965	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FE36_RS16990	COG1192	Involved in chromosome partitioning
FE36_RS16995	COG1475	DNA binding
FE36_RS17010	COG0463	Glycosyl transferase, family 2
FE36_RS17035	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FE36_RS17060	COG4221	oxidoreductase activity
FE36_RS17065	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FE36_RS17065	COG2755	lipolytic protein G-D-S-L family
FE36_RS17085	COG1166	arginine decarboxylase activity
FE36_RS17090	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FE36_RS17125	COG0606	chelatase, subunit chli
FE36_RS17135	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FE36_RS17180	COG1090	epimerase
FE36_RS17185	COG0642	Histidine kinase
FE36_RS17195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE36_RS17230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FE36_RS17245	COG0753	catalase activity
FE36_RS17285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE36_RS17290	COG0180	Tryptophanyl-tRNA synthetase
FE36_RS17295	COG3237	CsbD-like
FE36_RS17330	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FE36_RS17345	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FE36_RS17350	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FE36_RS17350	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FE36_RS17360	COG3228	Belongs to the MtfA family
FE36_RS17390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FE36_RS17410	COG1566	PFAM secretion protein HlyD family protein
FE36_RS17420	COG1199	ATP-dependent helicase activity
FE36_RS17450	COG0583	DNA-binding transcription factor activity
FE36_RS17480	COG0702	epimerase
FE36_RS17485	COG1733	regulation of RNA biosynthetic process
FE36_RS17510	COG0583	DNA-binding transcription factor activity
FE36_RS17515	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FE36_RS17525	COG2205	protein histidine kinase activity
FE36_RS17530	COG2205	protein histidine kinase activity
FE36_RS17535	COG0745	RESPONSE REGULATOR receiver
FE36_RS17555	COG1902	pentaerythritol trinitrate reductase activity
FE36_RS17560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FE36_RS17570	COG2814	Major facilitator Superfamily
FE36_RS17585	COG0084	hydrolase, TatD family'
FE36_RS17610	COG0702	epimerase
FE36_RS17635	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FE36_RS17655	COG1649	PFAM Uncharacterised BCR, COG1649
FE36_RS17660	COG2354	Protein conserved in bacteria
FE36_RS17665	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FE36_RS17680	COG3264	Mechanosensitive ion channel
FE36_RS17680	COG1511	domain protein
FE36_RS17750	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FE36_RS17835	COG0246	Mannitol dehydrogenase
FE36_RS17840	COG1472	Belongs to the glycosyl hydrolase 3 family
FE36_RS17850	COG4948	Mandelate Racemase Muconate Lactonizing
FE36_RS17860	COG3661	Belongs to the glycosyl hydrolase 67 family
FE36_RS17875	COG2974	May be involved in recombination
FE36_RS17895	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FE36_RS17905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FE36_RS17910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FE36_RS17915	COG0805	protein transport
FE36_RS17925	COG0519	Catalyzes the synthesis of GMP from XMP
FE36_RS17925	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FE36_RS17935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FE36_RS17940	COG0752	glycyl-tRNA synthetase alpha subunit
FE36_RS17950	COG0457	Tetratricopeptide repeat
FE36_RS17960	COG4771	TonB-dependent receptor
FE36_RS17965	COG0729	surface antigen
FE36_RS17970	COG2911	Protein conserved in bacteria
FE36_RS17995	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FE36_RS18000	COG1040	competence protein
FE36_RS18005	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FE36_RS18010	COG0156	8-amino-7-oxononanoate synthase activity
FE36_RS18050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FE36_RS18080	COG0657	acetylesterase activity
FE36_RS18090	COG1414	Transcriptional regulator
FE36_RS18095	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FE36_RS18100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FE36_RS18110	COG3485	protocatechuate 3,4-dioxygenase
FE36_RS18115	COG3485	protocatechuate 3,4-dioxygenase
FE36_RS18125	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FE36_RS18130	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FE36_RS18150	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FE36_RS18200	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FE36_RS18210	COG0129	dihydroxy-acid dehydratase activity
FE36_RS18215	COG2826	transposase and inactivated derivatives, IS30 family
FE36_RS18235	COG2211	Major facilitator Superfamily
FE36_RS18255	COG3693	PFAM glycoside hydrolase, family 10
FE36_RS18260	COG3693	PFAM glycoside hydrolase, family 10
FE36_RS18295	COG4770	biotin carboxylase activity
FE36_RS18300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FE36_RS18305	COG1960	acyl-CoA dehydrogenase activity
FE36_RS18350	COG0523	cobalamin synthesis protein
FE36_RS18365	COG0697	spore germination
FE36_RS18375	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FE36_RS18380	COG1846	Transcriptional regulator
FE36_RS18385	COG1764	response to oxidative stress
FE36_RS18420	COG0656	L-ascorbic acid biosynthetic process
FE36_RS18425	COG2130	NADP-dependent
FE36_RS18430	COG0667	Aldo Keto reductase
FE36_RS18440	COG1187	pseudouridine synthase activity
FE36_RS18450	COG1643	Atp-dependent helicase
FE36_RS18460	COG4807	Protein conserved in bacteria
FE36_RS18465	COG2351	hydroxyisourate hydrolase activity
FE36_RS18490	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FE36_RS18520	COG0604	alcohol dehydrogenase
FE36_RS18520	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_RS18520	COG3321	synthase
FE36_RS18525	COG2937	Belongs to the GPAT DAPAT family
FE36_RS18555	COG0284	orotidine-5'-phosphate decarboxylase activity
FE36_RS18560	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FE36_RS18580	COG0210	DNA helicase
FE36_RS18595	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FE36_RS18610	COG0564	pseudouridine synthase activity
FE36_RS18625	COG3706	GGDEF domain
FE36_RS18635	COG1929	Belongs to the glycerate kinase type-1 family
FE36_RS18640	COG2271	Major facilitator Superfamily
FE36_RS18655	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FE36_RS18665	COG0584	glycerophosphoryl diester phosphodiesterase
FE36_RS18675	COG0671	phosphoesterase, PA-phosphatase related
FE36_RS18680	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FE36_RS18685	COG0726	polysaccharide deacetylase
FE36_RS18705	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FE36_RS18720	COG0187	DNA topoisomerase II activity
FE36_RS18730	COG0501	Belongs to the peptidase M48B family
FE36_RS18760	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FE36_RS18770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE36_RS18890	COG4962	Type ii secretion system protein e
FE36_RS18905	COG3451	type IV secretory pathway VirB4
FE36_RS18995	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FE36_RS19085	COG3504	Conjugal transfer protein
FE36_RS19090	COG2948	multi-organism process
FE36_RS19095	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FE36_RS19180	COG2003	Belongs to the UPF0758 family
FE36_RS19190	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FE36_RS19210	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FE36_RS19215	COG1518	maintenance of DNA repeat elements
FE36_RS19285	COG0489	protein tyrosine kinase activity
FE36_RS19320	COG0084	hydrolase, TatD family'
FE36_RS19420	COG3328	transposase activity
FE36_RS19570	COG2801	Transposase and inactivated derivatives
FE36_RS19600	COG0582	viral genome integration into host DNA