locus-tag	class	description
OM954_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OM954_RS00020	COG0187	DNA topoisomerase II activity
OM954_RS00030	COG0501	Belongs to the peptidase M48B family
OM954_RS00075	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OM954_RS00085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM954_RS00130	COG0793	Belongs to the peptidase S41A family
OM954_RS00135	COG4942	peptidase
OM954_RS00145	COG2234	aminopeptidase activity
OM954_RS00155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM954_RS00160	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM954_RS00170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM954_RS00175	COG1064	alcohol dehydrogenase
OM954_RS00190	COG0493	'glutamate synthase
OM954_RS00195	COG0070	glutamate synthase
OM954_RS00195	COG0067	glutamate synthase
OM954_RS00195	COG0069	glutamate synthase activity
OM954_RS00285	COG1111	helicase
OM954_RS00285	COG1205	dead DEAH box helicase
OM954_RS00290	COG1272	protein, Hemolysin III
OM954_RS00310	COG0300	oxidoreductase activity
OM954_RS00315	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS00340	COG2249	NAD(P)H dehydrogenase (quinone) activity
OM954_RS00350	COG3039	Transposase
OM954_RS00365	COG3039	Transposase
OM954_RS00375	COG3237	CsbD-like
OM954_RS00425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM954_RS00430	COG0477	Major facilitator Superfamily
OM954_RS00475	COG0714	Associated with various cellular activities
OM954_RS00515	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
OM954_RS00525	COG4772	TonB-dependent receptor
OM954_RS00550	COG1304	FMN binding
OM954_RS00555	COG1755	Isoprenylcysteine carboxyl methyltransferase
OM954_RS00560	COG4585	Histidine kinase
OM954_RS00565	COG2197	response regulator
OM954_RS00590	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OM954_RS00595	COG3039	Transposase
OM954_RS00660	COG3328	transposase activity
OM954_RS00680	COG3039	Transposase
OM954_RS00685	COG3039	Transposase
OM954_RS00700	COG0366	Alpha amylase catalytic
OM954_RS00705	COG0366	Alpha amylase catalytic
OM954_RS00710	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM954_RS00730	COG0657	acetylesterase activity
OM954_RS00730	COG2755	lipolytic protein G-D-S-L family
OM954_RS00740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OM954_RS00755	COG3507	Belongs to the glycosyl hydrolase 43 family
OM954_RS00760	COG1609	Transcriptional regulator
OM954_RS00765	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OM954_RS00770	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS00780	COG2755	lipolytic protein G-D-S-L family
OM954_RS00790	COG3186	Phenylalanine-4-hydroxylase
OM954_RS00795	COG1522	sequence-specific DNA binding
OM954_RS00805	COG1752	Esterase of the alpha-beta hydrolase superfamily
OM954_RS00815	COG1119	ATPase activity
OM954_RS00830	COG1125	glycine betaine transport
OM954_RS00830	COG0517	IMP dehydrogenase activity
OM954_RS00845	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM954_RS00875	COG0489	protein tyrosine kinase activity
OM954_RS00880	COG2062	phosphohistidine phosphatase, SixA
OM954_RS00890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM954_RS00930	COG1968	undecaprenyl-diphosphatase activity
OM954_RS00935	COG0174	glutamine synthetase
OM954_RS00940	COG0347	Belongs to the P(II) protein family
OM954_RS00945	COG0004	ammonium transporteR
OM954_RS00950	COG3852	Histidine kinase
OM954_RS00955	COG2204	response regulator
OM954_RS00960	COG2032	superoxide dismutase activity
OM954_RS00965	COG2032	superoxide dismutase activity
OM954_RS00980	COG0183	Belongs to the thiolase family
OM954_RS01015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM954_RS01020	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
OM954_RS01025	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OM954_RS01050	COG2205	protein histidine kinase activity
OM954_RS01075	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OM954_RS01090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM954_RS01095	COG3177	Filamentation induced by cAMP protein fic
OM954_RS01100	COG0596	Alpha beta hydrolase
OM954_RS01105	COG0727	PFAM Uncharacterised protein family (UPF0153)
OM954_RS01110	COG0318	PFAM AMP-dependent synthetase and ligase
OM954_RS01115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM954_RS01130	COG1181	Belongs to the D-alanine--D-alanine ligase family
OM954_RS01140	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OM954_RS01150	COG0564	pseudouridine synthase activity
OM954_RS01170	COG1446	asparaginase
OM954_RS01175	COG0339	signal peptide processing
OM954_RS01210	COG0475	glutathione-regulated potassium exporter activity
OM954_RS01220	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OM954_RS01225	COG2224	Isocitrate lyase
OM954_RS01245	COG3039	Transposase
OM954_RS01265	COG4770	biotin carboxylase activity
OM954_RS01270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OM954_RS01275	COG1960	acyl-CoA dehydrogenase activity
OM954_RS01340	COG0697	spore germination
OM954_RS01350	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OM954_RS01355	COG1846	Transcriptional regulator
OM954_RS01360	COG1764	response to oxidative stress
OM954_RS01380	COG2130	NADP-dependent
OM954_RS01395	COG1187	pseudouridine synthase activity
OM954_RS01405	COG1643	Atp-dependent helicase
OM954_RS01410	COG4807	Protein conserved in bacteria
OM954_RS01420	COG2072	flavoprotein involved in K transport
OM954_RS01440	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OM954_RS01450	COG0583	DNA-binding transcription factor activity
OM954_RS01485	COG2252	PERMEase
OM954_RS01505	COG0084	hydrolase, TatD family'
OM954_RS01520	COG0583	DNA-binding transcription factor activity
OM954_RS01525	COG2814	Major facilitator Superfamily
OM954_RS01540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OM954_RS01545	COG1902	pentaerythritol trinitrate reductase activity
OM954_RS01565	COG0745	RESPONSE REGULATOR receiver
OM954_RS01570	COG2205	protein histidine kinase activity
OM954_RS01575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM954_RS01600	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OM954_RS01605	COG0583	DNA-binding transcription factor activity
OM954_RS01640	COG0702	epimerase
OM954_RS01645	COG1733	regulation of RNA biosynthetic process
OM954_RS01660	COG3328	transposase activity
OM954_RS01700	COG0129	dihydroxy-acid dehydratase activity
OM954_RS01715	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OM954_RS01770	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OM954_RS01775	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OM954_RS01800	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OM954_RS01815	COG3485	protocatechuate 3,4-dioxygenase
OM954_RS01820	COG3485	protocatechuate 3,4-dioxygenase
OM954_RS01830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM954_RS01835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OM954_RS01845	COG1414	Transcriptional regulator
OM954_RS01855	COG0657	acetylesterase activity
OM954_RS01865	COG0445	tRNA wobble uridine modification
OM954_RS01875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OM954_RS01905	COG2267	carboxylic ester hydrolase activity
OM954_RS01915	COG0156	8-amino-7-oxononanoate synthase activity
OM954_RS01920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OM954_RS01925	COG1040	competence protein
OM954_RS01930	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OM954_RS01950	COG3039	Transposase
OM954_RS01955	COG3328	transposase activity
OM954_RS02020	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OM954_RS02090	COG1511	domain protein
OM954_RS02090	COG3264	Mechanosensitive ion channel
OM954_RS02095	COG1368	sulfuric ester hydrolase activity
OM954_RS02100	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OM954_RS02105	COG2354	Protein conserved in bacteria
OM954_RS02115	COG0297	glycogen (starch) synthase activity
OM954_RS02120	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM954_RS02125	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM954_RS02150	COG0702	epimerase
OM954_RS02160	COG1858	cytochrome C peroxidase
OM954_RS02175	COG3328	transposase activity
OM954_RS02185	COG3039	Transposase
OM954_RS02195	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS02230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM954_RS02235	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS02245	COG0513	Belongs to the DEAD box helicase family
OM954_RS02250	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM954_RS02265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OM954_RS02275	COG3483	tryptophan 2,3-dioxygenase activity
OM954_RS02280	COG3104	oligopeptide transport
OM954_RS02300	COG2852	Protein conserved in bacteria
OM954_RS02305	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OM954_RS02325	COG1320	monovalent cation:proton antiporter activity
OM954_RS02330	COG2212	antiporter activity
OM954_RS02340	COG0651	ATP synthesis coupled electron transport
OM954_RS02345	COG1006	Multisubunit Na H antiporter MnhC subunit
OM954_RS02350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OM954_RS02350	COG2111	Na H antiporter
OM954_RS02370	COG3179	chitinase
OM954_RS02390	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OM954_RS02395	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OM954_RS02415	COG1597	lipid kinase activity
OM954_RS02445	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OM954_RS02450	COG0134	indole-3-glycerol-phosphate synthase activity
OM954_RS02460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM954_RS02465	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OM954_RS02475	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
OM954_RS02485	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OM954_RS02500	COG1051	belongs to the nudix hydrolase family
OM954_RS02540	COG0316	Belongs to the HesB IscA family
OM954_RS02555	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OM954_RS02570	COG2814	Major facilitator Superfamily
OM954_RS02580	COG2814	Major facilitator Superfamily
OM954_RS02585	COG1289	transmembrane transporter activity
OM954_RS02595	COG0151	Belongs to the GarS family
OM954_RS02605	COG0138	bifunctional purine biosynthesis protein purh
OM954_RS02610	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OM954_RS02615	COG2267	carboxylic ester hydrolase activity
OM954_RS02620	COG0671	phosphoesterase, PA-phosphatase related
OM954_RS02620	COG2453	phosphatase
OM954_RS02645	COG4589	Belongs to the CDS family
OM954_RS02650	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OM954_RS02670	COG2264	protein methyltransferase activity
OM954_RS02685	COG0439	Biotin carboxylase
OM954_RS02695	COG0511	ligase activity, forming carbon-carbon bonds
OM954_RS02700	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OM954_RS02710	COG1324	tolerance protein
OM954_RS02730	COG0459	protein refolding
OM954_RS02745	COG3550	peptidyl-serine autophosphorylation
OM954_RS02750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OM954_RS02765	COG3386	PFAM SMP-30 Gluconolaconase
OM954_RS02775	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OM954_RS02780	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OM954_RS02800	COG3039	Transposase
OM954_RS02820	COG0778	Nitroreductase
OM954_RS02825	COG2353	YceI-like domain
OM954_RS02860	COG3052	prosthetic group binding
OM954_RS02885	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OM954_RS02895	COG1802	Transcriptional regulator
OM954_RS02950	COG3328	transposase activity
OM954_RS02960	COG4221	oxidoreductase activity
OM954_RS02970	COG3039	Transposase
OM954_RS03000	COG4221	oxidoreductase activity
OM954_RS03010	COG0435	Glutathione S-transferase
OM954_RS03075	COG1959	2 iron, 2 sulfur cluster binding
OM954_RS03100	COG0697	spore germination
OM954_RS03105	COG4305	rare lipoprotein A
OM954_RS03110	COG5297	Belongs to the glycosyl hydrolase family 6
OM954_RS03120	COG1113	amino acid transport
OM954_RS03130	COG0598	Magnesium transport protein CorA
OM954_RS03175	COG5001	Diguanylate cyclase
OM954_RS03175	COG5002	protein histidine kinase activity
OM954_RS03175	COG3447	MASE1 domain protein
OM954_RS03185	COG0784	Response regulator, receiver
OM954_RS03185	COG2205	protein histidine kinase activity
OM954_RS03200	COG3468	outer membrane autotransporter barrel domain protein
OM954_RS03220	COG2943	transferase activity, transferring hexosyl groups
OM954_RS03230	COG3275	phosphorelay sensor kinase activity
OM954_RS03240	COG0181	hydroxymethylbilane synthase activity
OM954_RS03275	COG1505	serine-type exopeptidase activity
OM954_RS03285	COG0436	Aminotransferase
OM954_RS03295	COG2832	Protein of unknown function (DUF454)
OM954_RS03305	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OM954_RS03315	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OM954_RS03320	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OM954_RS03325	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OM954_RS03350	COG2226	methyltransferase
OM954_RS03355	COG3300	MHYT domain
OM954_RS03355	COG5001	Diguanylate cyclase
OM954_RS03360	COG0308	aminopeptidase N
OM954_RS03405	COG3284	Transcriptional regulator
OM954_RS03420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM954_RS03425	COG1077	Cell shape determining protein MreB Mrl
OM954_RS03430	COG1792	Involved in formation and maintenance of cell shape
OM954_RS03445	COG0772	Belongs to the SEDS family
OM954_RS03460	COG3039	Transposase
OM954_RS03495	COG2951	lytic endotransglycosylase activity
OM954_RS03500	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OM954_RS03505	COG1686	Belongs to the peptidase S11 family
OM954_RS03515	COG2921	Belongs to the UPF0250 family
OM954_RS03520	COG0321	lipoyl(octanoyl) transferase activity
OM954_RS03525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OM954_RS03550	COG1051	belongs to the nudix hydrolase family
OM954_RS03550	COG1056	cytidyltransferase-related domain
OM954_RS03585	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OM954_RS03590	COG0673	inositol 2-dehydrogenase activity
OM954_RS03595	COG2823	Periplasmic or secreted lipoprotein
OM954_RS03600	COG4251	negative regulation of phosphorylation
OM954_RS03605	COG0784	Response regulator, receiver
OM954_RS03610	COG4191	Histidine kinase
OM954_RS03615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OM954_RS03670	COG1459	type II secretion system
OM954_RS03715	COG2188	Transcriptional regulator
OM954_RS03725	COG1609	Transcriptional regulator
OM954_RS03730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OM954_RS03735	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OM954_RS03745	COG0617	tRNA 3'-terminal CCA addition
OM954_RS03760	COG0525	valine-tRNA ligase activity
OM954_RS03775	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OM954_RS03785	COG0795	lipopolysaccharide-transporting ATPase activity
OM954_RS03800	COG4974	Belongs to the 'phage' integrase family
OM954_RS03810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OM954_RS03815	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OM954_RS03815	COG0047	phosphoribosylformylglycinamidine synthase activity
OM954_RS03820	COG5295	Hep Hag repeat protein
OM954_RS03825	COG1404	Belongs to the peptidase S8 family
OM954_RS03830	COG5295	Hep Hag repeat protein
OM954_RS03835	COG1404	Belongs to the peptidase S8 family
OM954_RS03840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OM954_RS03845	COG1459	type II secretion system
OM954_RS03850	COG2165	general secretion pathway protein
OM954_RS03855	COG4970	Tfp pilus assembly protein FimT
OM954_RS03860	COG2165	general secretion pathway protein
OM954_RS03865	COG4795	General secretion pathway protein
OM954_RS03870	COG3156	type II secretion system protein K
OM954_RS03875	COG3166	PFAM Fimbrial assembly family protein
OM954_RS03890	COG1450	Type ii and iii secretion system protein
OM954_RS03900	COG2188	Transcriptional regulator
OM954_RS03970	COG1215	transferase activity, transferring glycosyl groups
OM954_RS03975	COG1215	transferase activity, transferring glycosyl groups
OM954_RS03980	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OM954_RS04005	COG0242	peptide deformylase activity
OM954_RS04010	COG0488	(ABC) transporter
OM954_RS04020	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OM954_RS04025	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OM954_RS04035	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM954_RS04035	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM954_RS04055	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OM954_RS04060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OM954_RS04065	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OM954_RS04080	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OM954_RS04085	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OM954_RS04095	COG2205	protein histidine kinase activity
OM954_RS04100	COG0745	RESPONSE REGULATOR receiver
OM954_RS04110	COG0277	FAD linked oxidase domain protein
OM954_RS04115	COG1988	membrane-bound metal-dependent
OM954_RS04120	COG0792	nuclease activity
OM954_RS04160	COG3116	cell division
OM954_RS04170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OM954_RS04175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OM954_RS04180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM954_RS04190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OM954_RS04195	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OM954_RS04200	COG1181	Belongs to the D-alanine--D-alanine ligase family
OM954_RS04205	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OM954_RS04220	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
OM954_RS04230	COG0739	heme binding
OM954_RS04235	COG0653	protein targeting
OM954_RS04240	COG0494	nUDIX hydrolase
OM954_RS04250	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OM954_RS04260	COG3321	synthase
OM954_RS04260	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS04260	COG0604	alcohol dehydrogenase
OM954_RS04275	COG0366	Alpha amylase catalytic
OM954_RS04310	COG2226	methyltransferase
OM954_RS04315	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OM954_RS04325	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OM954_RS04365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OM954_RS04375	COG4106	trans-aconitate 2-methyltransferase activity
OM954_RS04380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM954_RS04395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM954_RS04405	COG0667	Aldo Keto reductase
OM954_RS04415	COG4771	TonB-dependent receptor
OM954_RS04435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OM954_RS04440	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OM954_RS04450	COG2175	clavaminate synthase activity
OM954_RS04460	COG4181	ATPase activity
OM954_RS04475	COG0642	Histidine kinase
OM954_RS04485	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OM954_RS04495	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OM954_RS04505	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OM954_RS04510	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OM954_RS04525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OM954_RS04530	COG2967	ApaG domain
OM954_RS04535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OM954_RS04540	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OM954_RS04545	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM954_RS04550	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OM954_RS04560	COG0123	including yeast histone deacetylase and acetoin utilization protein
OM954_RS04565	COG2096	Adenosyltransferase
OM954_RS04575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM954_RS04580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM954_RS04610	COG3384	dioxygenase
OM954_RS04615	COG0583	DNA-binding transcription factor activity
OM954_RS04620	COG0318	PFAM AMP-dependent synthetase and ligase
OM954_RS04630	COG1024	Enoyl-CoA hydratase
OM954_RS04650	COG3386	PFAM SMP-30 Gluconolaconase
OM954_RS04660	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
OM954_RS04685	COG0697	spore germination
OM954_RS04695	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM954_RS04720	COG2197	response regulator
OM954_RS04730	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OM954_RS04745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OM954_RS04750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM954_RS04755	COG0583	DNA-binding transcription factor activity
OM954_RS04760	COG3634	alkyl hydroperoxide reductase activity
OM954_RS04770	COG2890	protein-(glutamine-N5) methyltransferase activity
OM954_RS04790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM954_RS04790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM954_RS04845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM954_RS04850	COG1404	Belongs to the peptidase S8 family
OM954_RS04855	COG1404	Belongs to the peptidase S8 family
OM954_RS04860	COG1404	Belongs to the peptidase S8 family
OM954_RS04865	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OM954_RS04890	COG1295	ribonuclease BN
OM954_RS04895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM954_RS04900	COG1254	Belongs to the acylphosphatase family
OM954_RS04915	COG0521	Mo-molybdopterin cofactor biosynthetic process
OM954_RS04925	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OM954_RS04930	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OM954_RS04940	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OM954_RS04945	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OM954_RS04955	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OM954_RS04960	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OM954_RS04965	COG0193	aminoacyl-tRNA hydrolase activity
OM954_RS04970	COG0012	GTP binding
OM954_RS04990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OM954_RS05005	COG0250	Participates in transcription elongation, termination and antitermination
OM954_RS05010	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OM954_RS05015	COG0081	regulation of translation
OM954_RS05020	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OM954_RS05030	COG0085	RNA polymerase activity
OM954_RS05035	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OM954_RS05040	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OM954_RS05045	COG0049	tRNA binding
OM954_RS05050	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OM954_RS05055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OM954_RS05075	COG3328	transposase activity
OM954_RS05080	COG0051	transcription antitermination factor activity, RNA binding
OM954_RS05085	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OM954_RS05090	COG0088	Forms part of the polypeptide exit tunnel
OM954_RS05095	COG0089	rRNA binding
OM954_RS05100	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OM954_RS05105	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OM954_RS05115	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OM954_RS05120	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OM954_RS05125	COG0255	Belongs to the universal ribosomal protein uL29 family
OM954_RS05130	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OM954_RS05140	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OM954_RS05145	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OM954_RS05155	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OM954_RS05160	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OM954_RS05165	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OM954_RS05175	COG1841	ribosomal large subunit assembly
OM954_RS05180	COG0200	Binds to the 23S rRNA
OM954_RS05185	COG0201	protein transport
OM954_RS05210	COG0203	ribosomal protein L17
OM954_RS05215	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OM954_RS05235	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
OM954_RS05245	COG0154	amidase activity
OM954_RS05255	COG1217	gtp-binding protein TYPA
OM954_RS05260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OM954_RS05265	COG0039	L-malate dehydrogenase activity
OM954_RS05270	COG0625	glutathione transferase activity
OM954_RS05285	COG1902	pentaerythritol trinitrate reductase activity
OM954_RS05285	COG0446	pyridine nucleotide-disulphide oxidoreductase
OM954_RS05290	COG0604	alcohol dehydrogenase
OM954_RS05295	COG3328	transposase activity
OM954_RS05300	COG3039	Transposase
OM954_RS05305	COG2885	chlorophyll binding
OM954_RS05325	COG0156	8-amino-7-oxononanoate synthase activity
OM954_RS05330	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OM954_RS05335	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OM954_RS05340	COG4208	sulfate ABC transporter
OM954_RS05345	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OM954_RS05360	COG3328	transposase activity
OM954_RS05385	COG0406	alpha-ribazole phosphatase activity
OM954_RS05395	COG0285	dihydrofolate synthase activity
OM954_RS05415	COG2833	Protein of unknown function (DUF455)
OM954_RS05430	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM954_RS05435	COG0671	phosphoesterase, PA-phosphatase related
OM954_RS05440	COG0438	transferase activity, transferring glycosyl groups
OM954_RS05450	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OM954_RS05465	COG4783	chaperone-mediated protein folding
OM954_RS05480	COG0473	3-isopropylmalate dehydrogenase activity
OM954_RS05520	COG3328	transposase activity
OM954_RS05535	COG0544	peptidyl-prolyl cis-trans isomerase activity
OM954_RS05545	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OM954_RS05575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM954_RS05585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM954_RS05595	COG0328	RNA-DNA hybrid ribonuclease activity
OM954_RS05600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OM954_RS05605	COG0631	protein serine/threonine phosphatase activity
OM954_RS05630	COG0859	PFAM glycosyl transferase family 9
OM954_RS05635	COG3642	lipopolysaccharide core region biosynthetic process
OM954_RS05640	COG1234	tRNA 3'-trailer cleavage
OM954_RS05645	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OM954_RS05655	COG0315	cyclic pyranopterin monophosphate synthase activity
OM954_RS05660	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OM954_RS05665	COG0314	molybdopterin synthase activity
OM954_RS05685	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OM954_RS05690	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OM954_RS05695	COG0537	adenosine 5'-monophosphoramidase activity
OM954_RS05715	COG0714	Associated with various cellular activities
OM954_RS05725	COG0424	maF-like protein
OM954_RS05730	COG1399	metal-binding, possibly nucleic acid-binding protein
OM954_RS05735	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OM954_RS05740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM954_RS05755	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS05770	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OM954_RS05775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OM954_RS05805	COG3829	transcription factor binding
OM954_RS05850	COG2373	Large extracellular alpha-helical protein
OM954_RS05870	COG3852	Histidine kinase
OM954_RS05875	COG4953	penicillin-binding protein 1C
OM954_RS05885	COG0678	peroxiredoxin activity
OM954_RS05905	COG0330	HflC and HflK could
OM954_RS05910	COG0330	HflC and HflK could
OM954_RS05920	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OM954_RS05925	COG0308	aminopeptidase N
OM954_RS05935	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS05940	COG1309	transcriptional regulator
OM954_RS05960	COG3328	transposase activity
OM954_RS05990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OM954_RS06000	COG3387	PFAM Glycoside hydrolase 15-related
OM954_RS06005	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS06010	COG3537	Alpha-1,2-mannosidase
OM954_RS06035	COG0492	ferredoxin-NADP+ reductase activity
OM954_RS06065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OM954_RS06070	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OM954_RS06075	COG2080	2 iron, 2 sulfur cluster binding
OM954_RS06110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OM954_RS06125	COG0587	DNA-directed DNA polymerase activity
OM954_RS06145	COG1297	OPT oligopeptide transporter protein
OM954_RS06170	COG0823	Involved in the tonB-independent uptake of proteins
OM954_RS06170	COG1506	peptidase
OM954_RS06205	COG1917	Cupin 2, conserved barrel domain protein
OM954_RS06205	COG2207	Transcriptional regulator
OM954_RS06215	COG3328	transposase activity
OM954_RS06225	COG0753	catalase activity
OM954_RS06230	COG0656	L-ascorbic acid biosynthetic process
OM954_RS06240	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OM954_RS06240	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OM954_RS06265	COG2814	Major facilitator Superfamily
OM954_RS06285	COG3328	transposase activity
OM954_RS06305	COG2194	sulfuric ester hydrolase activity
OM954_RS06320	COG0745	RESPONSE REGULATOR receiver
OM954_RS06325	COG0642	Histidine kinase
OM954_RS06335	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
OM954_RS06340	COG2894	cell division
OM954_RS06345	COG0850	regulation of cytokinetic process
OM954_RS06355	COG4585	Histidine kinase
OM954_RS06360	COG2197	response regulator
OM954_RS06375	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OM954_RS06400	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OM954_RS06410	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
OM954_RS06425	COG1595	DNA-templated transcription, initiation
OM954_RS06435	COG1946	Acyl-CoA thioesterase
OM954_RS06450	COG0824	Thioesterase
OM954_RS06455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OM954_RS06460	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OM954_RS06465	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OM954_RS06470	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OM954_RS06475	COG0268	Binds directly to 16S ribosomal RNA
OM954_RS06485	COG0196	riboflavin kinase activity
OM954_RS06490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OM954_RS06495	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OM954_RS06500	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OM954_RS06515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OM954_RS06520	COG1845	cytochrome c oxidase, subunit III
OM954_RS06525	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OM954_RS06540	COG3152	Membrane
OM954_RS06550	COG2207	Transcriptional regulator
OM954_RS06555	COG0326	Molecular chaperone. Has ATPase activity
OM954_RS06565	COG1366	Belongs to the anti-sigma-factor antagonist family
OM954_RS06570	COG1366	Belongs to the anti-sigma-factor antagonist family
OM954_RS06600	COG4771	TonB-dependent receptor
OM954_RS06610	COG5507	3-demethylubiquinone-9 3-methyltransferase
OM954_RS06615	COG2205	protein histidine kinase activity
OM954_RS06625	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OM954_RS06630	COG2205	protein histidine kinase activity
OM954_RS06630	COG3437	response regulator, receiver
OM954_RS06630	COG3850	Histidine kinase
OM954_RS06630	COG4999	Histidine kinase
OM954_RS06635	COG0784	Response regulator, receiver
OM954_RS06635	COG4191	Histidine kinase
OM954_RS06660	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OM954_RS06670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM954_RS06675	COG0228	four-way junction DNA binding
OM954_RS06680	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OM954_RS06685	COG0336	Belongs to the RNA methyltransferase TrmD family
OM954_RS06690	COG0335	large ribosomal subunit rRNA binding
OM954_RS06695	COG0534	Mate efflux family protein
OM954_RS06720	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OM954_RS06730	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OM954_RS06735	COG2801	Transposase and inactivated derivatives
OM954_RS06785	COG3250	beta-galactosidase activity
OM954_RS06790	COG3867	Arabinogalactan endo-beta-1,4-galactanase
OM954_RS06810	COG1960	acyl-CoA dehydrogenase activity
OM954_RS06840	COG0457	Tetratricopeptide repeat
OM954_RS06850	COG0457	Tetratricopeptide repeat
OM954_RS06860	COG1024	Enoyl-CoA hydratase
OM954_RS06860	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM954_RS06875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM954_RS06880	COG0481	GTPase activity
OM954_RS06895	COG0571	ribonuclease III activity
OM954_RS06900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OM954_RS06905	COG1381	Involved in DNA repair and RecF pathway recombination
OM954_RS06915	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OM954_RS06920	COG2954	triphosphatase activity
OM954_RS06925	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OM954_RS06930	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
OM954_RS06935	COG3046	protein related to deoxyribodipyrimidine photolyase
OM954_RS06940	COG1472	Belongs to the glycosyl hydrolase 3 family
OM954_RS06945	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OM954_RS06950	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OM954_RS06955	COG1278	Cold shock
OM954_RS06960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM954_RS06970	COG1201	RNA secondary structure unwinding
OM954_RS06975	COG1793	dna ligase
OM954_RS06985	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OM954_RS06985	COG1793	dna ligase
OM954_RS07020	COG0183	Belongs to the thiolase family
OM954_RS07045	COG1451	nucleotide metabolic process
OM954_RS07050	COG5487	UPF0391 membrane protein
OM954_RS07060	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OM954_RS07075	COG1077	Cell shape determining protein MreB Mrl
OM954_RS07080	COG1047	Peptidyl-prolyl cis-trans
OM954_RS07090	COG2824	Alkylphosphonate utilization operon protein PhnA
OM954_RS07100	COG1902	pentaerythritol trinitrate reductase activity
OM954_RS07105	COG2814	Major facilitator Superfamily
OM954_RS07140	COG0392	lysyltransferase activity
OM954_RS07140	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OM954_RS07150	COG0251	oxidation-reduction process
OM954_RS07155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OM954_RS07170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OM954_RS07195	COG1595	DNA-templated transcription, initiation
OM954_RS07210	COG2878	Part of a membrane complex involved in electron transport
OM954_RS07220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM954_RS07220	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM954_RS07240	COG0346	lactoylglutathione lyase activity
OM954_RS07255	COG0833	amino acid
OM954_RS07260	COG2040	homocysteine
OM954_RS07270	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OM954_RS07290	COG1695	Transcriptional regulator
OM954_RS07310	COG1981	membrane
OM954_RS07325	COG0825	malonyl-CoA metabolic process
OM954_RS07340	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM954_RS07345	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM954_RS07350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OM954_RS07355	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM954_RS07370	COG0750	zinc metalloprotease
OM954_RS07375	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OM954_RS07380	COG0575	Belongs to the CDS family
OM954_RS07385	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OM954_RS07390	COG0233	cytoplasmic translational termination
OM954_RS07395	COG0528	UMP kinase activity
OM954_RS07405	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OM954_RS07410	COG0052	Belongs to the universal ribosomal protein uS2 family
OM954_RS07460	COG1393	Belongs to the ArsC family
OM954_RS07465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM954_RS07475	COG0367	asparagine synthase
OM954_RS07485	COG4774	siderophore transport
OM954_RS07540	COG2801	Transposase and inactivated derivatives
OM954_RS07545	COG3328	transposase activity
OM954_RS07580	COG1566	PFAM secretion protein HlyD family protein
OM954_RS07585	COG2814	Major facilitator Superfamily
OM954_RS07615	COG3104	oligopeptide transport
OM954_RS07645	COG0339	signal peptide processing
OM954_RS07650	COG0386	Belongs to the glutathione peroxidase family
OM954_RS07710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OM954_RS07715	COG0084	hydrolase, TatD family'
OM954_RS07730	COG1960	acyl-CoA dehydrogenase activity
OM954_RS07745	COG0367	asparagine synthase
OM954_RS07755	COG0305	Participates in initiation and elongation during chromosome replication
OM954_RS07760	COG0415	Belongs to the DNA photolyase family
OM954_RS07775	COG0583	DNA-binding transcription factor activity
OM954_RS07820	COG3706	GGDEF domain
OM954_RS07845	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OM954_RS07860	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM954_RS07870	COG0497	DNA recombination
OM954_RS07875	COG1420	regulation of RNA biosynthetic process
OM954_RS07880	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OM954_RS07885	COG0443	Heat shock 70 kDa protein
OM954_RS07890	COG0484	heat shock protein binding
OM954_RS07895	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
OM954_RS07925	COG0583	DNA-binding transcription factor activity
OM954_RS07930	COG1132	(ABC) transporter
OM954_RS07965	COG2850	peptidyl-arginine hydroxylation
OM954_RS07985	COG1253	flavin adenine dinucleotide binding
OM954_RS08015	COG1131	(ABC) transporter
OM954_RS08020	COG1725	Transcriptional regulator
OM954_RS08030	COG0386	Belongs to the glutathione peroxidase family
OM954_RS08045	COG2900	Belongs to the SlyX family
OM954_RS08075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM954_RS08085	COG0646	methionine synthase
OM954_RS08085	COG1410	methionine synthase
OM954_RS08090	COG1410	methionine synthase
OM954_RS08090	COG0646	methionine synthase
OM954_RS08095	COG2226	methyltransferase
OM954_RS08100	COG1960	acyl-CoA dehydrogenase activity
OM954_RS08120	COG0557	exoribonuclease II activity
OM954_RS08130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM954_RS08140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OM954_RS08150	COG0704	Plays a role in the regulation of phosphate uptake
OM954_RS08155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OM954_RS08160	COG0581	inorganic phosphate transmembrane transporter activity
OM954_RS08165	COG0573	inorganic phosphate transmembrane transporter activity
OM954_RS08170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OM954_RS08195	COG0659	secondary active sulfate transmembrane transporter activity
OM954_RS08200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OM954_RS08210	COG1024	Enoyl-CoA hydratase
OM954_RS08220	COG0494	nUDIX hydrolase
OM954_RS08255	COG0488	(ABC) transporter
OM954_RS08265	COG0116	Belongs to the methyltransferase superfamily
OM954_RS08265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OM954_RS08270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OM954_RS08290	COG2925	Exonuclease
OM954_RS08300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM954_RS08305	COG3844	kynureninase activity
OM954_RS08315	COG0662	Cupin 2, conserved barrel domain protein
OM954_RS08320	COG0288	reversible hydration of carbon dioxide
OM954_RS08400	COG0017	Asparaginyl-tRNA synthetase
OM954_RS08405	COG0316	Belongs to the HesB IscA family
OM954_RS08410	COG0360	Binds together with S18 to 16S ribosomal RNA
OM954_RS08415	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OM954_RS08420	COG0359	binds to the 23S rRNA
OM954_RS08430	COG3115	cell septum assembly
OM954_RS08440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM954_RS08445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OM954_RS08450	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OM954_RS08460	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OM954_RS08470	COG4993	Dehydrogenase
OM954_RS08480	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OM954_RS08490	COG2986	histidine ammonia-lyase
OM954_RS08495	COG1228	amidohydrolase
OM954_RS08535	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
OM954_RS08540	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OM954_RS08545	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OM954_RS08550	COG0077	Prephenate dehydratase
OM954_RS08550	COG1605	Chorismate mutase
OM954_RS08555	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OM954_RS08570	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OM954_RS08575	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OM954_RS08580	COG0583	DNA-binding transcription factor activity
OM954_RS08605	COG0840	transmembrane signaling receptor activity
OM954_RS08625	COG0784	Response regulator, receiver
OM954_RS08625	COG4191	Histidine kinase
OM954_RS08630	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
OM954_RS08650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM954_RS08660	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OM954_RS08670	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OM954_RS08685	COG1595	DNA-templated transcription, initiation
OM954_RS08735	COG2244	polysaccharide biosynthetic process
OM954_RS08765	COG2264	protein methyltransferase activity
OM954_RS08790	COG1136	(ABC) transporter
OM954_RS08800	COG0477	Major facilitator Superfamily
OM954_RS08805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM954_RS08820	COG1253	flavin adenine dinucleotide binding
OM954_RS08830	COG0306	phosphate transporter
OM954_RS08855	COG0504	CTP synthase activity
OM954_RS08860	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OM954_RS08870	COG0148	phosphopyruvate hydratase activity
OM954_RS08875	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OM954_RS08885	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OM954_RS08890	COG0585	pseudouridine synthase activity
OM954_RS08895	COG2840	Smr protein MutS2
OM954_RS08900	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OM954_RS08905	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OM954_RS08910	COG1238	metal cluster binding
OM954_RS08920	COG3737	Protein of unknown function (DUF498/DUF598)
OM954_RS08925	COG1534	Rna-binding protein
OM954_RS08930	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OM954_RS08940	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OM954_RS08945	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OM954_RS08955	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OM954_RS08960	COG1546	Belongs to the CinA family
OM954_RS08970	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OM954_RS08975	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OM954_RS08980	COG2137	regulation of response to DNA damage stimulus
OM954_RS08985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OM954_RS08990	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OM954_RS09010	COG0583	DNA-binding transcription factor activity
OM954_RS09035	COG0351	phosphomethylpyrimidine kinase
OM954_RS09050	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OM954_RS09055	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OM954_RS09070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OM954_RS09080	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OM954_RS09085	COG3734	2-keto-3-deoxy-galactonokinase
OM954_RS09095	COG4948	Mandelate Racemase Muconate Lactonizing
OM954_RS09100	COG0800	Aldolase
OM954_RS09135	COG1501	Belongs to the glycosyl hydrolase 31 family
OM954_RS09145	COG1070	Carbohydrate kinase
OM954_RS09150	COG2115	Belongs to the xylose isomerase family
OM954_RS09155	COG0477	Major facilitator Superfamily
OM954_RS09170	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM954_RS09175	COG1469	GTP cyclohydrolase I activity
OM954_RS09200	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OM954_RS09205	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OM954_RS09210	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OM954_RS09215	COG0166	Belongs to the GPI family
OM954_RS09235	COG1472	Belongs to the glycosyl hydrolase 3 family
OM954_RS09245	COG2203	Gaf domain
OM954_RS09245	COG5001	Diguanylate cyclase
OM954_RS09245	COG4251	negative regulation of phosphorylation
OM954_RS09245	COG3706	GGDEF domain
OM954_RS09250	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM954_RS09255	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
OM954_RS09265	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OM954_RS09270	COG0671	phosphoesterase, PA-phosphatase related
OM954_RS09280	COG1794	racemase activity, acting on amino acids and derivatives
OM954_RS09285	COG0697	spore germination
OM954_RS09290	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OM954_RS09295	COG0167	dihydroorotate dehydrogenase activity
OM954_RS09310	COG1012	belongs to the aldehyde dehydrogenase family
OM954_RS09325	COG3328	transposase activity
OM954_RS09330	COG0366	Alpha amylase catalytic
OM954_RS09350	COG1082	Xylose isomerase domain protein TIM barrel
OM954_RS09360	COG2211	Major facilitator Superfamily
OM954_RS09375	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OM954_RS09380	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OM954_RS09395	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OM954_RS09400	COG0072	phenylalanine-tRNA ligase activity
OM954_RS09400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM954_RS09450	COG0438	transferase activity, transferring glycosyl groups
OM954_RS09455	COG0438	transferase activity, transferring glycosyl groups
OM954_RS09465	COG0438	transferase activity, transferring glycosyl groups
OM954_RS09490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM954_RS09500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM954_RS09520	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OM954_RS09530	COG1960	acyl-CoA dehydrogenase activity
OM954_RS09540	COG3040	lipid binding
OM954_RS09555	COG0322	excinuclease ABC activity
OM954_RS09590	COG1194	a g-specific adenine glycosylase
OM954_RS09595	COG0552	protein localization to endoplasmic reticulum
OM954_RS09605	COG3938	Belongs to the proline racemase family
OM954_RS09610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM954_RS09625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OM954_RS09635	COG0006	proline dipeptidase activity
OM954_RS09650	COG0531	amino acid
OM954_RS09745	COG3328	transposase activity
OM954_RS09755	COG0840	transmembrane signaling receptor activity
OM954_RS09795	COG3328	transposase activity
OM954_RS09805	COG3039	Transposase
OM954_RS09825	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
OM954_RS09830	COG3328	transposase activity
OM954_RS09835	COG0460	homoserine dehydrogenase
OM954_RS09835	COG0527	aspartate kinase activity
OM954_RS09870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM954_RS09875	COG0124	histidyl-tRNA synthetase
OM954_RS09885	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OM954_RS09890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OM954_RS09895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM954_RS09900	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OM954_RS09900	COG0131	Imidazoleglycerol-phosphate dehydratase
OM954_RS09905	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OM954_RS09910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OM954_RS09915	COG0107	imidazoleglycerol-phosphate synthase activity
OM954_RS09920	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OM954_RS09920	COG0140	phosphoribosyl-ATP diphosphatase activity
OM954_RS09935	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
OM954_RS09940	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OM954_RS09945	COG0235	Class ii aldolase
OM954_RS09950	COG0531	amino acid
OM954_RS09955	COG0531	amino acid
OM954_RS09965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OM954_RS09970	COG0277	FAD linked oxidase domain protein
OM954_RS09990	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OM954_RS10035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM954_RS10040	COG2258	MOSC domain
OM954_RS10045	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OM954_RS10050	COG0505	Belongs to the CarA family
OM954_RS10060	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OM954_RS10065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM954_RS10075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OM954_RS10095	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OM954_RS10105	COG0784	Response regulator, receiver
OM954_RS10105	COG2198	Histidine kinase
OM954_RS10105	COG2205	protein histidine kinase activity
OM954_RS10110	COG0784	Response regulator, receiver
OM954_RS10110	COG2198	Histidine kinase
OM954_RS10110	COG2205	protein histidine kinase activity
OM954_RS10115	COG1024	Enoyl-CoA hydratase
OM954_RS10120	COG0318	PFAM AMP-dependent synthetase and ligase
OM954_RS10155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM954_RS10165	COG2201	protein-glutamate methylesterase activity
OM954_RS10170	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OM954_RS10180	COG0840	transmembrane signaling receptor activity
OM954_RS10190	COG0835	chemotaxis
OM954_RS10200	COG0840	transmembrane signaling receptor activity
OM954_RS10205	COG0840	transmembrane signaling receptor activity
OM954_RS10210	COG0840	transmembrane signaling receptor activity
OM954_RS10215	COG0840	transmembrane signaling receptor activity
OM954_RS10220	COG0840	transmembrane signaling receptor activity
OM954_RS10235	COG0840	transmembrane signaling receptor activity
OM954_RS10240	COG0840	transmembrane signaling receptor activity
OM954_RS10245	COG0840	transmembrane signaling receptor activity
OM954_RS10250	COG0840	transmembrane signaling receptor activity
OM954_RS10260	COG0840	transmembrane signaling receptor activity
OM954_RS10275	COG0840	transmembrane signaling receptor activity
OM954_RS10280	COG0840	transmembrane signaling receptor activity
OM954_RS10290	COG0745	RESPONSE REGULATOR receiver
OM954_RS10300	COG0835	chemotaxis
OM954_RS10305	COG1192	Involved in chromosome partitioning
OM954_RS10310	COG1360	Flagellar Motor Protein
OM954_RS10315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OM954_RS10355	COG0784	Response regulator, receiver
OM954_RS10355	COG0643	Histidine kinase
OM954_RS10355	COG2198	Histidine kinase
OM954_RS10385	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OM954_RS10410	COG3039	Transposase
OM954_RS10420	COG1684	flagellar biosynthetic protein fliR
OM954_RS10430	COG3039	Transposase
OM954_RS10440	COG3190	flagellar
OM954_RS10490	COG1677	Flagellar hook-basal body complex protein FliE
OM954_RS10515	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OM954_RS10525	COG3039	Transposase
OM954_RS10530	COG3328	transposase activity
OM954_RS10555	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS10560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM954_RS10580	COG2201	protein-glutamate methylesterase activity
OM954_RS10590	COG2197	response regulator
OM954_RS10615	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OM954_RS10625	COG3039	Transposase
OM954_RS10630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OM954_RS10640	COG1705	Flagellar rod assembly protein muramidase FlgJ
OM954_RS10640	COG3951	Flagellar rod assembly protein muramidase FlgJ
OM954_RS10645	COG1706	bacterial-type flagellum-dependent cell motility
OM954_RS10650	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
OM954_RS10665	COG4787	bacterial-type flagellum-dependent cell motility
OM954_RS10675	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OM954_RS10680	COG1558	bacterial-type flagellum-dependent cell motility
OM954_RS10690	COG0784	Response regulator, receiver
OM954_RS10690	COG0835	chemotaxis
OM954_RS10710	COG5002	protein histidine kinase activity
OM954_RS10720	COG4585	Histidine kinase
OM954_RS10740	COG2915	High frequency lysogenization protein hflD homolog
OM954_RS10745	COG0482	sulfurtransferase activity
OM954_RS10765	COG0542	response to heat
OM954_RS10775	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OM954_RS10785	COG0492	ferredoxin-NADP+ reductase activity
OM954_RS10790	COG1674	ftsk spoiiie
OM954_RS10800	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OM954_RS10810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OM954_RS10815	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OM954_RS10820	COG0183	Belongs to the thiolase family
OM954_RS10825	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM954_RS10825	COG1024	Enoyl-CoA hydratase
OM954_RS10840	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OM954_RS10860	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM954_RS10865	COG1160	GTP binding
OM954_RS10870	COG0303	'Molybdopterin
OM954_RS10875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OM954_RS10910	COG0708	Exodeoxyribonuclease III
OM954_RS10920	COG0303	'Molybdopterin
OM954_RS10925	COG0746	molybdenum cofactor guanylyltransferase activity
OM954_RS10950	COG1648	precorrin-2 dehydrogenase activity
OM954_RS10950	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM954_RS10960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OM954_RS10965	COG2223	nitrite transmembrane transporter activity
OM954_RS10970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM954_RS10980	COG0243	molybdopterin cofactor binding
OM954_RS11000	COG3685	Protein conserved in bacteria
OM954_RS11020	COG5001	Diguanylate cyclase
OM954_RS11030	COG4566	intracellular signal transduction
OM954_RS11080	COG3328	transposase activity
OM954_RS11335	COG3039	Transposase
OM954_RS11385	COG3328	transposase activity
OM954_RS11400	COG1073	alpha beta
OM954_RS11400	COG2226	methyltransferase
OM954_RS11415	COG0363	glucosamine-6-phosphate deaminase activity
OM954_RS11500	COG3328	transposase activity
OM954_RS11520	COG1192	Involved in chromosome partitioning
OM954_RS11565	COG3318	Belongs to the UPF0149 family
OM954_RS11565	COG3012	SEC-C Motif Domain Protein
OM954_RS11595	COG3328	transposase activity
OM954_RS11625	COG1309	transcriptional regulator
OM954_RS11640	COG2154	pterin-4-alpha-carbinolamine dehydratase
OM954_RS11650	COG0428	transporter
OM954_RS11655	COG3064	Membrane
OM954_RS11665	COG1530	ribonuclease E activity
OM954_RS11670	COG3039	Transposase
OM954_RS11680	COG1054	Belongs to the UPF0176 family
OM954_RS11700	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OM954_RS11725	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OM954_RS11730	COG0322	excinuclease ABC activity
OM954_RS11740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OM954_RS11745	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OM954_RS11750	COG1663	tetraacyldisaccharide 4'-kinase activity
OM954_RS11755	COG1132	(ABC) transporter
OM954_RS11765	COG0811	peptide transport
OM954_RS11780	COG1136	(ABC) transporter
OM954_RS11785	COG4591	ABC-type transport system involved in lipoprotein release permease component
OM954_RS11795	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OM954_RS11800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OM954_RS11815	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OM954_RS11830	COG0354	folic acid binding
OM954_RS11840	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OM954_RS11845	COG0837	glucose binding
OM954_RS11850	COG0363	glucosamine-6-phosphate deaminase activity
OM954_RS11855	COG0129	dihydroxy-acid dehydratase activity
OM954_RS11860	COG0800	Aldolase
OM954_RS11925	COG0784	Response regulator, receiver
OM954_RS11925	COG2205	protein histidine kinase activity
OM954_RS11930	COG2183	response to ionizing radiation
OM954_RS11940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM954_RS11940	COG0723	plastoquinol--plastocyanin reductase activity
OM954_RS11955	COG3243	poly(R)-hydroxyalkanoic acid synthase
OM954_RS11965	COG1183	phosphatidylcholine synthase activity
OM954_RS11970	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS11985	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OM954_RS12000	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OM954_RS12015	COG1914	H( )-stimulated, divalent metal cation uptake system
OM954_RS12035	COG2814	Major facilitator Superfamily
OM954_RS12050	COG1335	isochorismatase
OM954_RS12065	COG2197	response regulator
OM954_RS12095	COG0583	DNA-binding transcription factor activity
OM954_RS12100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OM954_RS12105	COG3002	Belongs to the UPF0753 family
OM954_RS12115	COG0604	alcohol dehydrogenase
OM954_RS12120	COG3384	dioxygenase
OM954_RS12130	COG2801	Transposase and inactivated derivatives
OM954_RS12140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OM954_RS12155	COG0583	DNA-binding transcription factor activity
OM954_RS12200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OM954_RS12200	COG0519	Catalyzes the synthesis of GMP from XMP
OM954_RS12210	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OM954_RS12220	COG0475	glutathione-regulated potassium exporter activity
OM954_RS12220	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OM954_RS12225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OM954_RS12235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM954_RS12240	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
OM954_RS12250	COG0776	regulation of translation
OM954_RS12255	COG0539	negative regulation of cytoplasmic translation
OM954_RS12260	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OM954_RS12275	COG2957	Belongs to the agmatine deiminase family
OM954_RS12280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM954_RS12305	COG0395	ABC-type sugar transport system, permease component
OM954_RS12310	COG1175	transmembrane transport
OM954_RS12340	COG2350	Protein conserved in bacteria
OM954_RS12345	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OM954_RS12350	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OM954_RS12355	COG1187	pseudouridine synthase activity
OM954_RS12370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM954_RS12375	COG0436	Aminotransferase
OM954_RS12380	COG4133	protoheme IX ABC transporter activity
OM954_RS12400	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OM954_RS12425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM954_RS12435	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OM954_RS12440	COG4988	ABC transporter
OM954_RS12450	COG1294	oxidase, subunit
OM954_RS12480	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OM954_RS12485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OM954_RS12495	COG0165	Argininosuccinate lyase
OM954_RS12500	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OM954_RS12510	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OM954_RS12515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM954_RS12525	COG0137	argininosuccinate synthase activity
OM954_RS12530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OM954_RS12540	COG0215	cysteine-tRNA ligase activity
OM954_RS12545	COG2166	iron-sulfur cluster assembly
OM954_RS12565	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OM954_RS12570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OM954_RS12595	COG4302	ethanolamine ammonia-lyase activity
OM954_RS12625	COG3039	Transposase
OM954_RS12655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OM954_RS12660	COG0402	S-adenosylhomocysteine deaminase activity
OM954_RS12670	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OM954_RS12675	COG1509	lysine 2,3-aminomutase activity
OM954_RS12680	COG3300	MHYT domain
OM954_RS12680	COG5001	Diguanylate cyclase
OM954_RS12695	COG0483	inositol monophosphate 1-phosphatase activity
OM954_RS12700	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OM954_RS12715	COG0488	(ABC) transporter
OM954_RS12720	COG0513	Belongs to the DEAD box helicase family
OM954_RS12725	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OM954_RS12730	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OM954_RS12745	COG0625	glutathione transferase activity
OM954_RS12755	COG4681	YaeQ
OM954_RS12760	COG2081	HI0933 family
OM954_RS12770	COG0501	Belongs to the peptidase M48B family
OM954_RS12775	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM954_RS12780	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS12805	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OM954_RS12810	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM954_RS12815	COG0802	atpase or kinase
OM954_RS12820	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OM954_RS12820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OM954_RS12825	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OM954_RS12830	COG1570	exodeoxyribonuclease VII activity
OM954_RS12840	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM954_RS12885	COG0835	chemotaxis
OM954_RS12890	COG0840	transmembrane signaling receptor activity
OM954_RS12895	COG2094	Belongs to the DNA glycosylase MPG family
OM954_RS12900	COG1201	RNA secondary structure unwinding
OM954_RS12920	COG2969	positive regulation of protein catabolic process
OM954_RS12925	COG0625	glutathione transferase activity
OM954_RS12930	COG2857	Cytochrome c1
OM954_RS12935	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OM954_RS12940	COG0723	plastoquinol--plastocyanin reductase activity
OM954_RS12945	COG0741	lytic transglycosylase activity
OM954_RS12960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM954_RS12965	COG1702	phosphate starvation-inducible protein PhoH
OM954_RS12975	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OM954_RS12985	COG4535	Mg2 and Co2 transporter CorC
OM954_RS13000	COG1012	belongs to the aldehyde dehydrogenase family
OM954_RS13005	COG1177	transmembrane transport
OM954_RS13010	COG1176	ABC-type spermidine putrescine transport system, permease component I
OM954_RS13015	COG3842	ATPase activity
OM954_RS13035	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OM954_RS13055	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OM954_RS13060	COG0174	glutamine synthetase
OM954_RS13065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM954_RS13075	COG2703	oxygen carrier activity
OM954_RS13080	COG0477	Major facilitator Superfamily
OM954_RS13090	COG0243	molybdopterin cofactor binding
OM954_RS13095	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OM954_RS13100	COG2223	nitrite transmembrane transporter activity
OM954_RS13110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OM954_RS13120	COG2733	membrane
OM954_RS13125	COG0784	Response regulator, receiver
OM954_RS13125	COG2205	protein histidine kinase activity
OM954_RS13125	COG5002	protein histidine kinase activity
OM954_RS13135	COG0477	Major facilitator Superfamily
OM954_RS13140	COG0840	transmembrane signaling receptor activity
OM954_RS13170	COG2902	Dehydrogenase
OM954_RS13180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM954_RS13185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM954_RS13190	COG1609	Transcriptional regulator
OM954_RS13195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OM954_RS13195	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM954_RS13200	COG1105	Belongs to the carbohydrate kinase PfkB family
OM954_RS13205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OM954_RS13205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OM954_RS13225	COG3328	transposase activity
OM954_RS13230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OM954_RS13240	COG1862	Preprotein translocase
OM954_RS13245	COG0343	queuine tRNA-ribosyltransferase activity
OM954_RS13250	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OM954_RS13285	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OM954_RS13290	COG3291	Pkd domain containing protein
OM954_RS13295	COG0405	Gamma-glutamyltransferase
OM954_RS13300	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OM954_RS13310	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OM954_RS13315	COG0742	ribosomal rna small subunit methyltransferase
OM954_RS13320	COG0326	Molecular chaperone. Has ATPase activity
OM954_RS13395	COG3702	type iv secretory pathway
OM954_RS13415	COG2948	multi-organism process
OM954_RS13435	COG3505	Type IV secretory pathway VirD4
OM954_RS13450	COG0556	nucleotide-excision repair
OM954_RS13630	COG3179	chitinase
OM954_RS13675	COG4695	Portal protein
OM954_RS13765	COG1611	Belongs to the LOG family
OM954_RS13775	COG2095	MarC family integral membrane protein
OM954_RS13785	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OM954_RS13820	COG1185	polyribonucleotide nucleotidyltransferase activity
OM954_RS13825	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OM954_RS13830	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OM954_RS13835	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OM954_RS13840	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OM954_RS13845	COG0195	Participates in both transcription termination and antitermination
OM954_RS13850	COG0779	Required for maturation of 30S ribosomal subunits
OM954_RS13860	COG1007	ATP synthesis coupled electron transport
OM954_RS13885	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM954_RS13890	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OM954_RS13900	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OM954_RS13905	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
OM954_RS13910	COG0649	NAD binding
OM954_RS13915	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM954_RS13920	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM954_RS13925	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM954_RS13940	COG0149	triose-phosphate isomerase activity
OM954_RS13945	COG4221	oxidoreductase activity
OM954_RS13975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OM954_RS13980	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OM954_RS13985	COG0159	tryptophan synthase activity
OM954_RS13995	COG0133	tryptophan synthase activity
OM954_RS14005	COG0135	phosphoribosylanthranilate isomerase activity
OM954_RS14010	COG0101	tRNA pseudouridine synthase activity
OM954_RS14025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OM954_RS14030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OM954_RS14035	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OM954_RS14040	COG2890	protein-(glutamine-N5) methyltransferase activity
OM954_RS14050	COG0688	phosphatidylethanolamine metabolic process
OM954_RS14060	COG0433	COG0433 Predicted ATPase
OM954_RS14085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM954_RS14090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM954_RS14115	COG0717	Belongs to the dCTP deaminase family
OM954_RS14120	COG0489	protein tyrosine kinase activity
OM954_RS14150	COG3590	peptidase
OM954_RS14175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM954_RS14180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM954_RS14185	COG2311	Membrane
OM954_RS14190	COG1047	Peptidyl-prolyl cis-trans
OM954_RS14195	COG0791	NLP P60 protein
OM954_RS14200	COG0791	NLP P60 protein
OM954_RS14210	COG4106	trans-aconitate 2-methyltransferase activity
OM954_RS14215	COG1301	dicarboxylic acid transport
OM954_RS14220	COG1785	Belongs to the alkaline phosphatase family
OM954_RS14225	COG0037	tRNA processing
OM954_RS14230	COG1722	exodeoxyribonuclease VII activity
OM954_RS14235	COG0142	geranyltranstransferase activity
OM954_RS14240	COG4104	PAAR repeat-containing protein
OM954_RS14250	COG0312	modulator of DNA gyrase
OM954_RS14255	COG3028	Belongs to the UPF0307 family
OM954_RS14260	COG0312	modulator of DNA gyrase
OM954_RS14270	COG3164	Protein of unknown function
OM954_RS14280	COG0424	maF-like protein
OM954_RS14285	COG2968	Membrane
OM954_RS14300	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OM954_RS14315	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OM954_RS14330	COG0495	leucyl-tRNA aminoacylation
OM954_RS14340	COG3118	belongs to the thioredoxin family
OM954_RS14365	COG2155	Conserved Protein
OM954_RS14415	COG1132	(ABC) transporter
OM954_RS14445	COG0745	RESPONSE REGULATOR receiver
OM954_RS14450	COG5002	protein histidine kinase activity
OM954_RS14450	COG5000	phosphorelay sensor kinase activity
OM954_RS14455	COG0475	glutathione-regulated potassium exporter activity
OM954_RS14465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OM954_RS14485	COG1187	pseudouridine synthase activity
OM954_RS14490	COG5002	protein histidine kinase activity
OM954_RS14490	COG5001	Diguanylate cyclase
OM954_RS14500	COG1595	DNA-templated transcription, initiation
OM954_RS14615	COG0667	Aldo Keto reductase
OM954_RS14620	COG2814	Major facilitator Superfamily
OM954_RS14625	COG0583	DNA-binding transcription factor activity
OM954_RS14635	COG2207	Transcriptional regulator
OM954_RS14645	COG1309	transcriptional regulator
OM954_RS14655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM954_RS14670	COG0735	belongs to the Fur family
OM954_RS14675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM954_RS14700	COG4452	Inner membrane protein CreD
OM954_RS14720	COG0745	RESPONSE REGULATOR receiver
OM954_RS14725	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OM954_RS14740	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OM954_RS14750	COG0643	Histidine kinase
OM954_RS14750	COG2198	Histidine kinase
OM954_RS14755	COG0840	transmembrane signaling receptor activity
OM954_RS14760	COG0835	chemotaxis
OM954_RS14765	COG2202	Pas domain
OM954_RS14765	COG2199	diguanylate cyclase activity
OM954_RS14765	COG2200	EAL domain
OM954_RS14770	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OM954_RS14775	COG2201	protein-glutamate methylesterase activity
OM954_RS14785	COG3590	peptidase
OM954_RS14800	COG1515	deoxyribonuclease V activity
OM954_RS14810	COG1741	Belongs to the pirin family
OM954_RS14825	COG1741	Belongs to the pirin family
OM954_RS14830	COG1966	Carbon starvation protein
OM954_RS14835	COG2879	small protein
OM954_RS14870	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OM954_RS14875	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OM954_RS14880	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OM954_RS14885	COG2080	2 iron, 2 sulfur cluster binding
OM954_RS14890	COG0604	alcohol dehydrogenase
OM954_RS14890	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS14890	COG3321	synthase
OM954_RS14895	COG5001	Diguanylate cyclase
OM954_RS14895	COG4251	negative regulation of phosphorylation
OM954_RS14895	COG3706	GGDEF domain
OM954_RS14895	COG2203	Gaf domain
OM954_RS14900	COG0629	single-stranded DNA binding
OM954_RS14905	COG0142	geranyltranstransferase activity
OM954_RS14915	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OM954_RS14930	COG0527	aspartate kinase activity
OM954_RS14935	COG0384	phenazine biosynthesis protein PhzF
OM954_RS14940	COG0384	phenazine biosynthesis protein PhzF
OM954_RS14950	COG1764	response to oxidative stress
OM954_RS14955	COG0540	Belongs to the ATCase OTCase family
OM954_RS14960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OM954_RS14965	COG1678	Uncharacterized ACR, COG1678
OM954_RS14970	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OM954_RS14975	COG0519	Catalyzes the synthesis of GMP from XMP
OM954_RS15000	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OM954_RS15015	COG0739	heme binding
OM954_RS15035	COG0693	protein deglycase activity
OM954_RS15045	COG1959	2 iron, 2 sulfur cluster binding
OM954_RS15050	COG0719	Fe-S assembly protein
OM954_RS15055	COG0396	ATPase activity
OM954_RS15060	COG0719	Fe-S assembly protein
OM954_RS15065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OM954_RS15070	COG0456	acetyltransferase
OM954_RS15075	COG2146	nitrite reductase [NAD(P)H] activity
OM954_RS15080	COG4774	siderophore transport
OM954_RS15085	COG3128	pkhd-type hydroxylase
OM954_RS15110	COG3328	transposase activity
OM954_RS15115	COG1477	protein flavinylation
OM954_RS15120	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OM954_RS15130	COG1555	photosystem II stabilization
OM954_RS15150	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OM954_RS15160	COG0628	permease
OM954_RS15170	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OM954_RS15185	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OM954_RS15205	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OM954_RS15210	COG0271	Belongs to the BolA IbaG family
OM954_RS15220	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OM954_RS15230	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OM954_RS15235	COG1137	ATPase activity
OM954_RS15250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM954_RS15255	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OM954_RS15260	COG1660	Displays ATPase and GTPase activities
OM954_RS15270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM954_RS15285	COG2239	Acts as a magnesium transporter
OM954_RS15295	COG1294	oxidase, subunit
OM954_RS15345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM954_RS15345	COG0551	DNA topoisomerase type I activity
OM954_RS15360	COG2951	lytic endotransglycosylase activity
OM954_RS15430	COG1271	oxidase subunit
OM954_RS15440	COG1113	amino acid transport
OM954_RS15465	COG2197	response regulator
OM954_RS15470	COG0531	amino acid
OM954_RS15535	COG2814	Major facilitator Superfamily
OM954_RS15540	COG0754	glutathionylspermidine amidase activity
OM954_RS15565	COG1842	Phage shock protein A
OM954_RS15575	COG0259	pyridoxamine-phosphate oxidase activity
OM954_RS15580	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OM954_RS15585	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OM954_RS15595	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OM954_RS15600	COG2814	Major facilitator Superfamily
OM954_RS15625	COG2205	protein histidine kinase activity
OM954_RS15625	COG0784	Response regulator, receiver
OM954_RS15625	COG2198	Histidine kinase
OM954_RS15630	COG2353	YceI-like domain
OM954_RS15650	COG1760	l-serine dehydratase
OM954_RS15660	COG0460	homoserine dehydrogenase
OM954_RS15660	COG0527	aspartate kinase activity
OM954_RS15665	COG0626	cystathionine gamma-synthase activity
OM954_RS15670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM954_RS15675	COG0739	heme binding
OM954_RS15680	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OM954_RS15685	COG1272	protein, Hemolysin III
OM954_RS15690	COG2982	Protein involved in outer membrane biogenesis
OM954_RS15695	COG0516	GMP reductase activity
OM954_RS15695	COG0517	IMP dehydrogenase activity
OM954_RS15700	COG0463	Glycosyl transferase, family 2
OM954_RS15705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM954_RS15710	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OM954_RS15720	COG4771	TonB-dependent receptor
OM954_RS15725	COG1309	transcriptional regulator
OM954_RS15735	COG1960	acyl-CoA dehydrogenase activity
OM954_RS15760	COG3328	transposase activity
OM954_RS15785	COG0509	glycine decarboxylation via glycine cleavage system
OM954_RS15790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OM954_RS15800	COG0330	HflC and HflK could
OM954_RS15805	COG1742	UPF0060 membrane protein
OM954_RS15810	COG3956	TIGRFAM MazG family protein
OM954_RS15820	COG0494	nUDIX hydrolase
OM954_RS15830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OM954_RS15835	COG0837	glucose binding
OM954_RS15860	COG3858	chitin binding
OM954_RS15860	COG1388	LysM domain
OM954_RS15865	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OM954_RS15875	COG1472	Belongs to the glycosyl hydrolase 3 family
OM954_RS15930	COG3142	Participates in the control of copper homeostasis
OM954_RS15935	COG1446	asparaginase
OM954_RS15960	COG0643	Histidine kinase
OM954_RS15960	COG2198	Histidine kinase
OM954_RS15960	COG0784	Response regulator, receiver
OM954_RS15965	COG0840	transmembrane signaling receptor activity
OM954_RS15985	COG0189	ligase activity
OM954_RS15995	COG1397	ADP-ribosylglycohydrolase
OM954_RS16005	COG1199	ATP-dependent helicase activity
OM954_RS16015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM954_RS16020	COG1215	transferase activity, transferring glycosyl groups
OM954_RS16030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OM954_RS16040	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OM954_RS16045	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
OM954_RS16050	COG0535	radical SAM domain protein
OM954_RS16055	COG0535	radical SAM domain protein
OM954_RS16070	COG0837	glucose binding
OM954_RS16080	COG3328	transposase activity
OM954_RS16090	COG1643	Atp-dependent helicase
OM954_RS16095	COG0783	Belongs to the Dps family
OM954_RS16100	COG0514	ATP-dependent DNA helicase (RecQ)
OM954_RS16140	COG0840	transmembrane signaling receptor activity
OM954_RS16160	COG3920	Histidine kinase
OM954_RS16165	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OM954_RS16175	COG0602	queuosine metabolic process
OM954_RS16185	COG2885	chlorophyll binding
OM954_RS16190	COG0823	Involved in the tonB-independent uptake of proteins
OM954_RS16200	COG0848	biopolymer transport protein
OM954_RS16210	COG0824	Thioesterase
OM954_RS16215	COG2255	four-way junction helicase activity
OM954_RS16225	COG3158	transport of potassium into the cell
OM954_RS16230	COG0632	four-way junction helicase activity
OM954_RS16235	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OM954_RS16240	COG0217	transcriptional regulatory protein
OM954_RS16255	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OM954_RS16270	COG0477	Major facilitator Superfamily
OM954_RS16290	COG0657	acetylesterase activity
OM954_RS16290	COG2755	lipolytic protein G-D-S-L family
OM954_RS16310	COG0488	(ABC) transporter
OM954_RS16375	COG4772	TonB-dependent receptor
OM954_RS16385	COG4264	IucA IucC family
OM954_RS16400	COG0019	diaminopimelate decarboxylase activity
OM954_RS16430	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OM954_RS16440	COG1492	cobalamin metabolic process
OM954_RS16450	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OM954_RS16475	COG4206	TonB-dependent receptor
OM954_RS16485	COG0542	response to heat
OM954_RS16530	COG1877	trehalose-phosphatase activity
OM954_RS16535	COG3387	PFAM Glycoside hydrolase 15-related
OM954_RS16555	COG0840	transmembrane signaling receptor activity
OM954_RS16560	COG3011	Protein conserved in bacteria
OM954_RS16575	COG0564	pseudouridine synthase activity
OM954_RS16580	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM954_RS16590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM954_RS16590	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OM954_RS16605	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OM954_RS16610	COG0045	succinate-CoA ligase (ADP-forming) activity
OM954_RS16650	COG3328	transposase activity
OM954_RS16660	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OM954_RS16665	COG0237	dephospho-CoA kinase activity
OM954_RS16690	COG0745	RESPONSE REGULATOR receiver
OM954_RS16700	COG0189	ligase activity
OM954_RS16730	COG2801	Transposase and inactivated derivatives
OM954_RS16745	COG2003	Belongs to the UPF0758 family
OM954_RS16770	COG3328	transposase activity
OM954_RS16850	COG2003	Belongs to the UPF0758 family
OM954_RS16920	COG2022	thiamine diphosphate biosynthetic process
OM954_RS16925	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OM954_RS16930	COG0471	metal ion transport
OM954_RS16930	COG3273	potassium ion transport
OM954_RS16955	COG1970	mechanosensitive ion channel activity
OM954_RS16965	COG1609	Transcriptional regulator
OM954_RS16975	COG3250	beta-galactosidase activity
OM954_RS16980	COG4948	Mandelate Racemase Muconate Lactonizing
OM954_RS16990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM954_RS17000	COG0308	aminopeptidase N
OM954_RS17005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM954_RS17015	COG0529	Catalyzes the synthesis of activated sulfate
OM954_RS17015	COG2895	sulfate adenylyltransferase (ATP) activity
OM954_RS17020	COG0175	sulfate reduction
OM954_RS17025	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OM954_RS17030	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM954_RS17035	COG0175	sulfate reduction
OM954_RS17055	COG2205	protein histidine kinase activity
OM954_RS17055	COG2198	Histidine kinase
OM954_RS17055	COG0784	Response regulator, receiver
OM954_RS17070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM954_RS17070	COG1648	precorrin-2 dehydrogenase activity
OM954_RS17085	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
OM954_RS17090	COG3588	fructose-bisphosphate aldolase
OM954_RS17095	COG0469	pyruvate kinase activity
OM954_RS17105	COG0126	phosphoglycerate kinase activity
OM954_RS17135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OM954_RS17145	COG3047	cAMP biosynthetic process
OM954_RS17160	COG3453	Protein conserved in bacteria
OM954_RS17160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM954_RS17165	COG0725	ABC transporter, periplasmic molybdate-binding protein
OM954_RS17170	COG4149	molybdate abc transporter
OM954_RS17175	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OM954_RS17195	COG0642	Histidine kinase
OM954_RS17220	COG1022	Amp-dependent synthetase and ligase
OM954_RS17245	COG1376	ErfK ybiS ycfS ynhG family protein
OM954_RS17250	COG0739	heme binding
OM954_RS17255	COG4773	Receptor
OM954_RS17270	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OM954_RS17275	COG1301	dicarboxylic acid transport
OM954_RS17285	COG2304	oxidoreductase activity
OM954_RS17305	COG0714	Associated with various cellular activities
OM954_RS17335	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OM954_RS17355	COG1957	nucleoside hydrolase
OM954_RS17360	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OM954_RS17370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OM954_RS17385	COG1561	YicC-like family, N-terminal region
OM954_RS17390	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OM954_RS17400	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OM954_RS17405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OM954_RS17420	COG0006	proline dipeptidase activity
OM954_RS17430	COG0006	proline dipeptidase activity
OM954_RS17435	COG3079	Belongs to the UPF0149 family
OM954_RS17455	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OM954_RS17475	COG2912	Transglutaminase-like superfamily
OM954_RS17480	COG1773	rubredoxin
OM954_RS17485	COG0352	thiamine-phosphate diphosphorylase activity
OM954_RS17505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OM954_RS17515	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
OM954_RS17520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM954_RS17550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OM954_RS17555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM954_RS17560	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS17570	COG0671	phosphoesterase, PA-phosphatase related
OM954_RS17580	COG3781	membrane
OM954_RS17590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OM954_RS17595	COG0563	adenylate kinase activity
OM954_RS17610	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
OM954_RS17620	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OM954_RS17640	COG3710	Transcriptional regulator
OM954_RS17645	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OM954_RS17655	COG0840	transmembrane signaling receptor activity
OM954_RS17660	COG0405	Gamma-glutamyltransferase
OM954_RS17665	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OM954_RS17685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OM954_RS17690	COG0473	3-isopropylmalate dehydrogenase activity
OM954_RS17695	COG0066	3-isopropylmalate dehydratase activity
OM954_RS17700	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OM954_RS17720	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OM954_RS17725	COG1538	Outer membrane efflux protein
OM954_RS17730	COG1519	Transferase
OM954_RS17735	COG1560	Kdo2-lipid A biosynthetic process
OM954_RS17760	COG0280	phosphate acetyltransferase
OM954_RS17760	COG0281	malic enzyme
OM954_RS17765	COG1301	dicarboxylic acid transport
OM954_RS17790	COG0583	DNA-binding transcription factor activity
OM954_RS17795	COG0667	Aldo Keto reductase
OM954_RS17810	COG2197	response regulator
OM954_RS17820	COG0642	Histidine kinase
OM954_RS17835	COG2851	Citrate transporter
OM954_RS17840	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS17845	COG1609	Transcriptional regulator
OM954_RS17850	COG2211	Major facilitator Superfamily
OM954_RS17875	COG1162	GTPase activity
OM954_RS17880	COG0436	Aminotransferase
OM954_RS17895	COG0726	polysaccharide deacetylase
OM954_RS17900	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OM954_RS17915	COG3964	amidohydrolase
OM954_RS17920	COG0402	S-adenosylhomocysteine deaminase activity
OM954_RS17945	COG3328	transposase activity
OM954_RS17955	COG1307	EDD domain protein, DegV family
OM954_RS17970	COG2801	Transposase and inactivated derivatives
OM954_RS17980	COG3791	Glutathione-dependent formaldehyde-activating
OM954_RS18010	COG2205	protein histidine kinase activity
OM954_RS18025	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OM954_RS18040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OM954_RS18050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OM954_RS18055	COG1012	belongs to the aldehyde dehydrogenase family
OM954_RS18060	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
OM954_RS18085	COG1183	phosphatidylcholine synthase activity
OM954_RS18095	COG0442	prolyl-tRNA aminoacylation
OM954_RS18110	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OM954_RS18115	COG1127	ABC transporter
OM954_RS18120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OM954_RS18120	COG3218	ABC-type transport auxiliary lipoprotein component
OM954_RS18150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OM954_RS18155	COG0662	Cupin 2, conserved barrel domain protein
OM954_RS18155	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
OM954_RS18185	COG2086	electron transfer activity
OM954_RS18200	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OM954_RS18200	COG0546	phosphoglycolate phosphatase activity
OM954_RS18205	COG0277	FAD linked oxidase domain protein
OM954_RS18215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM954_RS18250	COG3328	transposase activity
OM954_RS18260	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
OM954_RS18265	COG0438	transferase activity, transferring glycosyl groups
OM954_RS18290	COG0438	transferase activity, transferring glycosyl groups
OM954_RS18295	COG0626	cystathionine gamma-synthase activity
OM954_RS18325	COG0625	glutathione transferase activity
OM954_RS18335	COG0513	Belongs to the DEAD box helicase family
OM954_RS18340	COG0720	synthase
OM954_RS18350	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OM954_RS18360	COG1956	GAF domain-containing protein
OM954_RS18375	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OM954_RS18380	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OM954_RS18390	COG4991	sh3 domain protein
OM954_RS18400	COG0339	signal peptide processing
OM954_RS18415	COG2132	Multicopper oxidase
OM954_RS18450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OM954_RS18455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM954_RS18460	COG1136	(ABC) transporter
OM954_RS18465	COG1136	(ABC) transporter
OM954_RS18465	COG0577	efflux transmembrane transporter activity
OM954_RS18485	COG4191	Histidine kinase
OM954_RS18490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OM954_RS18515	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OM954_RS18520	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OM954_RS18525	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OM954_RS18530	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OM954_RS18535	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OM954_RS18550	COG0356	it plays a direct role in the translocation of protons across the membrane
OM954_RS18570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM954_RS18580	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM954_RS18615	COG2011	ABC-type metal ion transport system permease component
OM954_RS18620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OM954_RS18625	COG0697	spore germination
OM954_RS18630	COG1666	GTP binding
OM954_RS18640	COG0784	Response regulator, receiver
OM954_RS18640	COG2198	Histidine kinase
OM954_RS18640	COG5002	protein histidine kinase activity
OM954_RS18665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OM954_RS18670	COG1187	pseudouridine synthase activity
OM954_RS18675	COG2813	Specifically methylates the guanine in position
OM954_RS18690	COG3039	Transposase
OM954_RS18695	COG3328	transposase activity
OM954_RS18710	COG2202	Pas domain
OM954_RS18710	COG2205	protein histidine kinase activity
OM954_RS18730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OM954_RS18735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM954_RS18790	COG0842	Transport permease protein
OM954_RS18795	COG1131	(ABC) transporter
OM954_RS18800	COG0025	NhaP-type Na H and K H
OM954_RS18805	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
OM954_RS18810	COG1573	uracil-dna glycosylase
OM954_RS18820	COG3384	dioxygenase
OM954_RS18830	COG0583	DNA-binding transcription factor activity
OM954_RS18840	COG0667	Aldo Keto reductase
OM954_RS18855	COG3590	peptidase
OM954_RS18870	COG0531	amino acid
OM954_RS18885	COG2972	Histidine kinase
OM954_RS18900	COG3685	Protein conserved in bacteria
OM954_RS18905	COG3546	catalase activity
OM954_RS18955	COG1271	oxidase subunit
OM954_RS18960	COG1294	oxidase, subunit
OM954_RS18975	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS18995	COG1063	alcohol dehydrogenase
OM954_RS19005	COG3328	transposase activity
OM954_RS19075	COG0251	oxidation-reduction process
OM954_RS19105	COG0659	secondary active sulfate transmembrane transporter activity
OM954_RS19110	COG0038	chloride channel
OM954_RS19120	COG0024	Methionine aminopeptidase
OM954_RS19135	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS19155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OM954_RS19160	COG1490	D-aminoacyl-tRNA deacylase activity
OM954_RS19165	COG1560	Kdo2-lipid A biosynthetic process
OM954_RS19210	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OM954_RS19210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OM954_RS19215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OM954_RS19220	COG0242	peptide deformylase activity
OM954_RS19225	COG1652	LysM domain
OM954_RS19230	COG0758	DNA mediated transformation
OM954_RS19250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM954_RS19250	COG1754	DNA topoisomerase type I activity
OM954_RS19255	COG0009	L-threonylcarbamoyladenylate synthase
OM954_RS19270	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS19280	COG0616	signal peptide processing
OM954_RS19285	COG0534	Mate efflux family protein
OM954_RS19305	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OM954_RS19310	COG0625	glutathione transferase activity
OM954_RS19330	COG2860	membrane
OM954_RS19335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OM954_RS19340	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OM954_RS19345	COG2201	protein-glutamate methylesterase activity
OM954_RS19350	COG2177	Part of the ABC transporter FtsEX involved in
OM954_RS19355	COG2884	Cell division ATP-binding protein ftsE
OM954_RS19360	COG0513	Belongs to the DEAD box helicase family
OM954_RS19365	COG3118	belongs to the thioredoxin family
OM954_RS19370	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OM954_RS19380	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
OM954_RS19405	COG1652	LysM domain
OM954_RS19410	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OM954_RS19410	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OM954_RS19415	COG1473	amidohydrolase
OM954_RS19420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM954_RS19425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM954_RS19445	COG5383	Protein conserved in bacteria
OM954_RS19485	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
OM954_RS19490	COG3023	N-Acetylmuramoyl-L-alanine amidase
OM954_RS19510	COG0531	amino acid
OM954_RS19530	COG3328	transposase activity
OM954_RS19540	COG2133	pyrroloquinoline quinone binding
OM954_RS19550	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OM954_RS19555	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OM954_RS19570	COG1610	YqeY-like protein
OM954_RS19575	COG1295	ribonuclease BN
OM954_RS19580	COG0358	DNA primase activity
OM954_RS19595	COG0109	protoheme IX farnesyltransferase activity
OM954_RS19625	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
OM954_RS19640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OM954_RS19680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OM954_RS19685	COG0739	heme binding
OM954_RS19690	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OM954_RS19700	COG2223	nitrite transmembrane transporter activity
OM954_RS19705	COG0708	Exodeoxyribonuclease III
OM954_RS19710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OM954_RS19720	COG1192	Involved in chromosome partitioning
OM954_RS19725	COG1475	DNA binding
OM954_RS19740	COG0463	Glycosyl transferase, family 2
OM954_RS19760	COG0756	dUTP diphosphatase activity
OM954_RS19765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OM954_RS19770	COG2003	Belongs to the UPF0758 family
OM954_RS19775	COG0018	arginyl-trna synthetase
OM954_RS19790	COG4221	oxidoreductase activity
OM954_RS19795	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OM954_RS19795	COG2755	lipolytic protein G-D-S-L family
OM954_RS19820	COG1166	arginine decarboxylase activity
OM954_RS19825	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OM954_RS19845	COG3291	Pkd domain containing protein
OM954_RS19845	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OM954_RS19860	COG0606	chelatase, subunit chli
OM954_RS19875	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OM954_RS19900	COG1690	Belongs to the RtcB family
OM954_RS19940	COG1090	epimerase
OM954_RS19950	COG0642	Histidine kinase
OM954_RS19970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM954_RS19995	COG1011	Hydrolase
OM954_RS20000	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OM954_RS20015	COG0753	catalase activity
OM954_RS20030	COG2197	response regulator
OM954_RS20035	COG4585	Histidine kinase
OM954_RS20040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM954_RS20045	COG1136	(ABC) transporter
OM954_RS20070	COG0697	spore germination
OM954_RS20095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM954_RS20100	COG0180	Tryptophanyl-tRNA synthetase
OM954_RS20105	COG3237	CsbD-like
OM954_RS20145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OM954_RS20160	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OM954_RS20165	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OM954_RS20165	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OM954_RS20175	COG3228	Belongs to the MtfA family
OM954_RS20205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM954_RS20250	COG3328	transposase activity
OM954_RS20265	COG1199	ATP-dependent helicase activity
OM954_RS20280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OM954_RS20370	COG4555	ABC transporter
OM954_RS20380	COG1476	TRANSCRIPTIONal
OM954_RS20400	COG1230	cation diffusion facilitator family transporter
OM954_RS20405	COG0543	2 iron, 2 sulfur cluster binding
OM954_RS20405	COG0633	Ferredoxin
OM954_RS20410	COG1131	(ABC) transporter
OM954_RS20415	COG0842	Transport permease protein
OM954_RS20420	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OM954_RS20445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM954_RS20465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OM954_RS20470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OM954_RS20485	COG1042	CoA-binding domain protein
OM954_RS20485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM954_RS20485	COG0045	succinate-CoA ligase (ADP-forming) activity
OM954_RS20490	COG2239	Acts as a magnesium transporter
OM954_RS20510	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OM954_RS20515	COG3387	PFAM Glycoside hydrolase 15-related
OM954_RS20530	COG3100	YcgL domain-containing protein
OM954_RS20535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OM954_RS20545	COG0463	Glycosyl transferase, family 2
OM954_RS20555	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS20610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM954_RS20645	COG0408	coproporphyrinogen oxidase activity
OM954_RS20680	COG0515	serine threonine protein kinase
OM954_RS20685	COG0631	protein serine/threonine phosphatase activity
OM954_RS20710	COG0667	Aldo Keto reductase
OM954_RS20715	COG0583	DNA-binding transcription factor activity
OM954_RS20790	COG0154	amidase activity
OM954_RS20815	COG3328	transposase activity
OM954_RS20895	COG0210	DNA helicase
OM954_RS20910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM954_RS20915	COG0583	DNA-binding transcription factor activity
OM954_RS20920	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OM954_RS20930	COG2159	amidohydrolase
OM954_RS20955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM954_RS20975	COG0357	Ribosomal RNA small subunit methyltransferase G
OM954_RS20980	COG3540	Alkaline phosphatase
OM954_RS20990	COG2091	lysine biosynthetic process via aminoadipic acid
OM954_RS21005	COG0708	Exodeoxyribonuclease III
OM954_RS21010	COG1846	Transcriptional regulator
OM954_RS21010	COG1940	carbohydrate kinase activity
OM954_RS21030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM954_RS21035	COG3162	membrane
OM954_RS21045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OM954_RS21080	COG3507	Belongs to the glycosyl hydrolase 43 family
OM954_RS21100	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS21105	COG0179	Fumarylacetoacetate (FAA) hydrolase
OM954_RS21110	COG4948	Mandelate Racemase Muconate Lactonizing
OM954_RS21115	COG3254	rhamnose metabolic process
OM954_RS21120	COG0738	Major facilitator superfamily
OM954_RS21125	COG1414	Transcriptional regulator
OM954_RS21130	COG2207	Transcriptional regulator
OM954_RS21130	COG1917	Cupin 2, conserved barrel domain protein
OM954_RS21140	COG1971	Probably functions as a manganese efflux pump
OM954_RS21145	COG2205	protein histidine kinase activity
OM954_RS21155	COG3459	Glycosyltransferase 36 associated
OM954_RS21160	COG2211	Major facilitator Superfamily
OM954_RS21165	COG3265	gluconokinase activity
OM954_RS21170	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM954_RS21190	COG2911	Protein conserved in bacteria
OM954_RS21195	COG0729	surface antigen
OM954_RS21200	COG4771	TonB-dependent receptor
OM954_RS21205	COG0457	Tetratricopeptide repeat
OM954_RS21215	COG0752	glycyl-tRNA synthetase alpha subunit
OM954_RS21220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OM954_RS21235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OM954_RS21235	COG0519	Catalyzes the synthesis of GMP from XMP
OM954_RS21250	COG0805	protein transport
OM954_RS21255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OM954_RS21260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OM954_RS21270	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OM954_RS21290	COG2974	May be involved in recombination
OM954_RS21295	COG0037	tRNA processing
OM954_RS21300	COG2115	Belongs to the xylose isomerase family
OM954_RS21310	COG3661	Belongs to the glycosyl hydrolase 67 family
OM954_RS21320	COG4948	Mandelate Racemase Muconate Lactonizing
OM954_RS21330	COG1472	Belongs to the glycosyl hydrolase 3 family
OM954_RS21335	COG0246	Mannitol dehydrogenase
OM954_RS21390	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OM954_RS21415	COG3386	PFAM SMP-30 Gluconolaconase
OM954_RS21425	COG3250	beta-galactosidase activity
OM954_RS21430	COG1904	glucuronate isomerase
OM954_RS21435	COG3693	PFAM glycoside hydrolase, family 10
OM954_RS21450	COG3693	PFAM glycoside hydrolase, family 10
OM954_RS21465	COG2211	Major facilitator Superfamily
OM954_RS21545	COG2937	Belongs to the GPAT DAPAT family
OM954_RS21575	COG0284	orotidine-5'-phosphate decarboxylase activity
OM954_RS21580	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
OM954_RS21595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OM954_RS21645	COG0210	DNA helicase
OM954_RS21650	COG1435	thymidine kinase activity
OM954_RS21660	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
OM954_RS21670	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OM954_RS21700	COG3135	benzoate transporter
OM954_RS21725	COG0676	glucose-6-phosphate 1-epimerase activity
OM954_RS21735	COG3012	SEC-C Motif Domain Protein
OM954_RS21775	COG3328	transposase activity
OM954_RS21800	COG3328	transposase activity
OM954_RS21825	COG0302	gtp cyclohydrolase
OM954_RS21840	COG1566	PFAM secretion protein HlyD family protein
OM954_RS21850	COG1289	transmembrane transporter activity
OM954_RS21855	COG0477	Major facilitator Superfamily
OM954_RS21865	COG0583	DNA-binding transcription factor activity
OM954_RS21870	COG4221	oxidoreductase activity
OM954_RS21880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM954_RS21905	COG3328	transposase activity
OM954_RS21930	COG0564	pseudouridine synthase activity
OM954_RS21970	COG3012	SEC-C Motif Domain Protein
OM954_RS22040	COG4790	Type iii secretion
OM954_RS22160	COG3328	transposase activity
OM954_RS22210	COG3039	Transposase
OM954_RS22215	COG3328	transposase activity
OM954_RS22250	COG2801	Transposase and inactivated derivatives
OM954_RS22320	COG0439	Biotin carboxylase
OM954_RS22345	COG1028	Short-chain dehydrogenase reductase Sdr
OM954_RS22400	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OM954_RS22405	COG1074	ATP-dependent DNA helicase activity
OM954_RS22410	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OM954_RS22445	COG1127	ABC transporter
OM954_RS22450	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OM954_RS22455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OM954_RS22470	COG2853	Lipoprotein
OM954_RS22480	COG0386	Belongs to the glutathione peroxidase family
OM954_RS22490	COG1322	Protein conserved in bacteria
OM954_RS22500	COG0583	DNA-binding transcription factor activity
OM954_RS22520	COG0531	amino acid
OM954_RS22525	COG3537	Alpha-1,2-mannosidase
OM954_RS22545	COG2203	Gaf domain
OM954_RS22545	COG2199	diguanylate cyclase activity
OM954_RS22550	COG3835	regulator
OM954_RS22555	COG1929	Belongs to the glycerate kinase type-1 family
OM954_RS22575	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OM954_RS22580	COG0861	Integral membrane protein TerC family
OM954_RS22590	COG0584	glycerophosphoryl diester phosphodiesterase
OM954_RS22605	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OM954_RS22610	COG0726	polysaccharide deacetylase
OM954_RS22620	COG0706	membrane insertase activity
OM954_RS22625	COG0594	ribonuclease P activity
OM954_RS22825	COG4962	Type ii secretion system protein e
OM954_RS22840	COG3451	type IV secretory pathway VirB4
OM954_RS22865	COG3846	protein secretion by the type IV secretion system
OM954_RS22900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM954_RS22915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM954_RS22930	COG1487	ribonuclease activity
OM954_RS22935	COG4691	Plasmid stability protein
OM954_RS22940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OM954_RS22980	COG3328	transposase activity