locus-tag	class	description
XppCFBP6546P_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XppCFBP6546P_RS00020	COG0187	DNA topoisomerase II activity
XppCFBP6546P_RS00030	COG0501	Belongs to the peptidase M48B family
XppCFBP6546P_RS00075	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XppCFBP6546P_RS00085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XppCFBP6546P_RS00130	COG0793	Belongs to the peptidase S41A family
XppCFBP6546P_RS00135	COG4942	peptidase
XppCFBP6546P_RS00145	COG2234	aminopeptidase activity
XppCFBP6546P_RS00155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XppCFBP6546P_RS00160	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XppCFBP6546P_RS00170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XppCFBP6546P_RS00175	COG1064	alcohol dehydrogenase
XppCFBP6546P_RS00190	COG0493	'glutamate synthase
XppCFBP6546P_RS00195	COG0067	glutamate synthase
XppCFBP6546P_RS00195	COG0069	glutamate synthase activity
XppCFBP6546P_RS00195	COG0070	glutamate synthase
XppCFBP6546P_RS00285	COG1205	dead DEAH box helicase
XppCFBP6546P_RS00285	COG1111	helicase
XppCFBP6546P_RS00290	COG1272	protein, Hemolysin III
XppCFBP6546P_RS00310	COG0300	oxidoreductase activity
XppCFBP6546P_RS00315	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS00340	COG2249	NAD(P)H dehydrogenase (quinone) activity
XppCFBP6546P_RS00350	COG3039	Transposase
XppCFBP6546P_RS00365	COG3039	Transposase
XppCFBP6546P_RS00375	COG3237	CsbD-like
XppCFBP6546P_RS00425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XppCFBP6546P_RS00430	COG0477	Major facilitator Superfamily
XppCFBP6546P_RS00475	COG0714	Associated with various cellular activities
XppCFBP6546P_RS00515	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XppCFBP6546P_RS00525	COG4772	TonB-dependent receptor
XppCFBP6546P_RS00550	COG1304	FMN binding
XppCFBP6546P_RS00555	COG1755	Isoprenylcysteine carboxyl methyltransferase
XppCFBP6546P_RS00560	COG4585	Histidine kinase
XppCFBP6546P_RS00565	COG2197	response regulator
XppCFBP6546P_RS00590	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XppCFBP6546P_RS00640	COG3039	Transposase
XppCFBP6546P_RS00645	COG3039	Transposase
XppCFBP6546P_RS00660	COG0366	Alpha amylase catalytic
XppCFBP6546P_RS00665	COG0366	Alpha amylase catalytic
XppCFBP6546P_RS00670	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XppCFBP6546P_RS00690	COG2755	lipolytic protein G-D-S-L family
XppCFBP6546P_RS00690	COG0657	acetylesterase activity
XppCFBP6546P_RS00700	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XppCFBP6546P_RS00715	COG3507	Belongs to the glycosyl hydrolase 43 family
XppCFBP6546P_RS00720	COG1609	Transcriptional regulator
XppCFBP6546P_RS00725	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XppCFBP6546P_RS00730	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS00740	COG2755	lipolytic protein G-D-S-L family
XppCFBP6546P_RS00750	COG3186	Phenylalanine-4-hydroxylase
XppCFBP6546P_RS00755	COG1522	sequence-specific DNA binding
XppCFBP6546P_RS00765	COG1752	Esterase of the alpha-beta hydrolase superfamily
XppCFBP6546P_RS00775	COG1119	ATPase activity
XppCFBP6546P_RS00790	COG0517	IMP dehydrogenase activity
XppCFBP6546P_RS00790	COG1125	glycine betaine transport
XppCFBP6546P_RS00805	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XppCFBP6546P_RS00835	COG0489	protein tyrosine kinase activity
XppCFBP6546P_RS00840	COG2062	phosphohistidine phosphatase, SixA
XppCFBP6546P_RS00850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XppCFBP6546P_RS00890	COG1968	undecaprenyl-diphosphatase activity
XppCFBP6546P_RS00895	COG0174	glutamine synthetase
XppCFBP6546P_RS00900	COG0347	Belongs to the P(II) protein family
XppCFBP6546P_RS00905	COG0004	ammonium transporteR
XppCFBP6546P_RS00910	COG3852	Histidine kinase
XppCFBP6546P_RS00915	COG2204	response regulator
XppCFBP6546P_RS00920	COG2032	superoxide dismutase activity
XppCFBP6546P_RS00925	COG2032	superoxide dismutase activity
XppCFBP6546P_RS00940	COG0183	Belongs to the thiolase family
XppCFBP6546P_RS00975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XppCFBP6546P_RS00980	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XppCFBP6546P_RS00985	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XppCFBP6546P_RS01010	COG2205	protein histidine kinase activity
XppCFBP6546P_RS01035	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XppCFBP6546P_RS01050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XppCFBP6546P_RS01055	COG3177	Filamentation induced by cAMP protein fic
XppCFBP6546P_RS01060	COG0596	Alpha beta hydrolase
XppCFBP6546P_RS01065	COG0727	PFAM Uncharacterised protein family (UPF0153)
XppCFBP6546P_RS01070	COG0318	PFAM AMP-dependent synthetase and ligase
XppCFBP6546P_RS01075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XppCFBP6546P_RS01090	COG1181	Belongs to the D-alanine--D-alanine ligase family
XppCFBP6546P_RS01100	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XppCFBP6546P_RS01110	COG0564	pseudouridine synthase activity
XppCFBP6546P_RS01130	COG1446	asparaginase
XppCFBP6546P_RS01135	COG0339	signal peptide processing
XppCFBP6546P_RS01170	COG0475	glutathione-regulated potassium exporter activity
XppCFBP6546P_RS01180	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XppCFBP6546P_RS01185	COG2224	Isocitrate lyase
XppCFBP6546P_RS01205	COG3039	Transposase
XppCFBP6546P_RS01225	COG4770	biotin carboxylase activity
XppCFBP6546P_RS01230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XppCFBP6546P_RS01235	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6546P_RS01300	COG0697	spore germination
XppCFBP6546P_RS01310	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XppCFBP6546P_RS01315	COG1846	Transcriptional regulator
XppCFBP6546P_RS01320	COG1764	response to oxidative stress
XppCFBP6546P_RS01340	COG2130	NADP-dependent
XppCFBP6546P_RS01355	COG1187	pseudouridine synthase activity
XppCFBP6546P_RS01365	COG1643	Atp-dependent helicase
XppCFBP6546P_RS01370	COG4807	Protein conserved in bacteria
XppCFBP6546P_RS01380	COG2072	flavoprotein involved in K transport
XppCFBP6546P_RS01400	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XppCFBP6546P_RS01410	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS01445	COG2252	PERMEase
XppCFBP6546P_RS01465	COG0084	hydrolase, TatD family'
XppCFBP6546P_RS01480	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS01485	COG2814	Major facilitator Superfamily
XppCFBP6546P_RS01500	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XppCFBP6546P_RS01505	COG1902	pentaerythritol trinitrate reductase activity
XppCFBP6546P_RS01525	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_RS01530	COG2205	protein histidine kinase activity
XppCFBP6546P_RS01535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6546P_RS01560	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XppCFBP6546P_RS01565	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS01600	COG0702	epimerase
XppCFBP6546P_RS01605	COG1733	regulation of RNA biosynthetic process
XppCFBP6546P_RS01620	COG3328	transposase activity
XppCFBP6546P_RS01660	COG0129	dihydroxy-acid dehydratase activity
XppCFBP6546P_RS01675	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XppCFBP6546P_RS01730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XppCFBP6546P_RS01735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XppCFBP6546P_RS01760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XppCFBP6546P_RS01775	COG3485	protocatechuate 3,4-dioxygenase
XppCFBP6546P_RS01780	COG3485	protocatechuate 3,4-dioxygenase
XppCFBP6546P_RS01790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XppCFBP6546P_RS01795	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XppCFBP6546P_RS01805	COG1414	Transcriptional regulator
XppCFBP6546P_RS01815	COG0657	acetylesterase activity
XppCFBP6546P_RS01825	COG0445	tRNA wobble uridine modification
XppCFBP6546P_RS01835	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XppCFBP6546P_RS01865	COG2267	carboxylic ester hydrolase activity
XppCFBP6546P_RS01875	COG0156	8-amino-7-oxononanoate synthase activity
XppCFBP6546P_RS01880	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XppCFBP6546P_RS01885	COG1040	competence protein
XppCFBP6546P_RS01890	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XppCFBP6546P_RS01910	COG3039	Transposase
XppCFBP6546P_RS01975	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XppCFBP6546P_RS02045	COG1511	domain protein
XppCFBP6546P_RS02045	COG3264	Mechanosensitive ion channel
XppCFBP6546P_RS02050	COG1368	sulfuric ester hydrolase activity
XppCFBP6546P_RS02055	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XppCFBP6546P_RS02060	COG2354	Protein conserved in bacteria
XppCFBP6546P_RS02070	COG0297	glycogen (starch) synthase activity
XppCFBP6546P_RS02075	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XppCFBP6546P_RS02080	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XppCFBP6546P_RS02105	COG0702	epimerase
XppCFBP6546P_RS02130	COG3328	transposase activity
XppCFBP6546P_RS02140	COG3039	Transposase
XppCFBP6546P_RS02155	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS02190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP6546P_RS02195	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS02205	COG0513	Belongs to the DEAD box helicase family
XppCFBP6546P_RS02210	COG0508	dehydrogenase complex catalyzes the overall conversion of
XppCFBP6546P_RS02225	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XppCFBP6546P_RS02235	COG3483	tryptophan 2,3-dioxygenase activity
XppCFBP6546P_RS02240	COG3104	oligopeptide transport
XppCFBP6546P_RS02260	COG2852	Protein conserved in bacteria
XppCFBP6546P_RS02265	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XppCFBP6546P_RS02280	COG1320	monovalent cation:proton antiporter activity
XppCFBP6546P_RS02285	COG2212	antiporter activity
XppCFBP6546P_RS02295	COG0651	ATP synthesis coupled electron transport
XppCFBP6546P_RS02300	COG1006	Multisubunit Na H antiporter MnhC subunit
XppCFBP6546P_RS02305	COG2111	Na H antiporter
XppCFBP6546P_RS02305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XppCFBP6546P_RS02350	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XppCFBP6546P_RS02355	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XppCFBP6546P_RS02375	COG1597	lipid kinase activity
XppCFBP6546P_RS02405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XppCFBP6546P_RS02410	COG0134	indole-3-glycerol-phosphate synthase activity
XppCFBP6546P_RS02420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XppCFBP6546P_RS02425	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XppCFBP6546P_RS02435	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XppCFBP6546P_RS02445	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XppCFBP6546P_RS02460	COG1051	belongs to the nudix hydrolase family
XppCFBP6546P_RS02500	COG0316	Belongs to the HesB IscA family
XppCFBP6546P_RS02515	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XppCFBP6546P_RS02530	COG2814	Major facilitator Superfamily
XppCFBP6546P_RS02540	COG2814	Major facilitator Superfamily
XppCFBP6546P_RS02545	COG1289	transmembrane transporter activity
XppCFBP6546P_RS02555	COG0151	Belongs to the GarS family
XppCFBP6546P_RS02565	COG0138	bifunctional purine biosynthesis protein purh
XppCFBP6546P_RS02570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XppCFBP6546P_RS02575	COG2267	carboxylic ester hydrolase activity
XppCFBP6546P_RS02580	COG2453	phosphatase
XppCFBP6546P_RS02580	COG0671	phosphoesterase, PA-phosphatase related
XppCFBP6546P_RS02605	COG4589	Belongs to the CDS family
XppCFBP6546P_RS02610	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XppCFBP6546P_RS02630	COG2264	protein methyltransferase activity
XppCFBP6546P_RS02645	COG0439	Biotin carboxylase
XppCFBP6546P_RS02655	COG0511	ligase activity, forming carbon-carbon bonds
XppCFBP6546P_RS02660	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XppCFBP6546P_RS02670	COG1324	tolerance protein
XppCFBP6546P_RS02690	COG0459	protein refolding
XppCFBP6546P_RS02705	COG3550	peptidyl-serine autophosphorylation
XppCFBP6546P_RS02710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XppCFBP6546P_RS02725	COG3386	PFAM SMP-30 Gluconolaconase
XppCFBP6546P_RS02735	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XppCFBP6546P_RS02740	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XppCFBP6546P_RS02760	COG3039	Transposase
XppCFBP6546P_RS02780	COG0778	Nitroreductase
XppCFBP6546P_RS02785	COG2353	YceI-like domain
XppCFBP6546P_RS02820	COG3052	prosthetic group binding
XppCFBP6546P_RS02845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XppCFBP6546P_RS02855	COG1802	Transcriptional regulator
XppCFBP6546P_RS02910	COG3328	transposase activity
XppCFBP6546P_RS02925	COG4221	oxidoreductase activity
XppCFBP6546P_RS02950	COG4221	oxidoreductase activity
XppCFBP6546P_RS02960	COG0435	Glutathione S-transferase
XppCFBP6546P_RS03025	COG1959	2 iron, 2 sulfur cluster binding
XppCFBP6546P_RS03050	COG0697	spore germination
XppCFBP6546P_RS03055	COG4305	rare lipoprotein A
XppCFBP6546P_RS03060	COG5297	Belongs to the glycosyl hydrolase family 6
XppCFBP6546P_RS03070	COG1113	amino acid transport
XppCFBP6546P_RS03080	COG0598	Magnesium transport protein CorA
XppCFBP6546P_RS03125	COG3447	MASE1 domain protein
XppCFBP6546P_RS03125	COG5001	Diguanylate cyclase
XppCFBP6546P_RS03125	COG5002	protein histidine kinase activity
XppCFBP6546P_RS03140	COG0784	Response regulator, receiver
XppCFBP6546P_RS03140	COG2205	protein histidine kinase activity
XppCFBP6546P_RS03170	COG2943	transferase activity, transferring hexosyl groups
XppCFBP6546P_RS03180	COG3275	phosphorelay sensor kinase activity
XppCFBP6546P_RS03190	COG0181	hydroxymethylbilane synthase activity
XppCFBP6546P_RS03225	COG1505	serine-type exopeptidase activity
XppCFBP6546P_RS03235	COG0436	Aminotransferase
XppCFBP6546P_RS03245	COG2832	Protein of unknown function (DUF454)
XppCFBP6546P_RS03255	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XppCFBP6546P_RS03265	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XppCFBP6546P_RS03270	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XppCFBP6546P_RS03275	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XppCFBP6546P_RS03300	COG2226	methyltransferase
XppCFBP6546P_RS03305	COG3300	MHYT domain
XppCFBP6546P_RS03305	COG5001	Diguanylate cyclase
XppCFBP6546P_RS03310	COG0308	aminopeptidase N
XppCFBP6546P_RS03355	COG3284	Transcriptional regulator
XppCFBP6546P_RS03370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XppCFBP6546P_RS03375	COG1077	Cell shape determining protein MreB Mrl
XppCFBP6546P_RS03380	COG1792	Involved in formation and maintenance of cell shape
XppCFBP6546P_RS03395	COG0772	Belongs to the SEDS family
XppCFBP6546P_RS03410	COG3039	Transposase
XppCFBP6546P_RS03435	COG2951	lytic endotransglycosylase activity
XppCFBP6546P_RS03440	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XppCFBP6546P_RS03445	COG1686	Belongs to the peptidase S11 family
XppCFBP6546P_RS03455	COG2921	Belongs to the UPF0250 family
XppCFBP6546P_RS03460	COG0321	lipoyl(octanoyl) transferase activity
XppCFBP6546P_RS03465	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XppCFBP6546P_RS03490	COG1051	belongs to the nudix hydrolase family
XppCFBP6546P_RS03490	COG1056	cytidyltransferase-related domain
XppCFBP6546P_RS03525	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XppCFBP6546P_RS03530	COG0673	inositol 2-dehydrogenase activity
XppCFBP6546P_RS03535	COG2823	Periplasmic or secreted lipoprotein
XppCFBP6546P_RS03540	COG4251	negative regulation of phosphorylation
XppCFBP6546P_RS03545	COG0784	Response regulator, receiver
XppCFBP6546P_RS03550	COG4191	Histidine kinase
XppCFBP6546P_RS03555	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XppCFBP6546P_RS03610	COG1459	type II secretion system
XppCFBP6546P_RS03655	COG2188	Transcriptional regulator
XppCFBP6546P_RS03665	COG1609	Transcriptional regulator
XppCFBP6546P_RS03670	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XppCFBP6546P_RS03675	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XppCFBP6546P_RS03685	COG0617	tRNA 3'-terminal CCA addition
XppCFBP6546P_RS03700	COG0525	valine-tRNA ligase activity
XppCFBP6546P_RS03715	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XppCFBP6546P_RS03725	COG0795	lipopolysaccharide-transporting ATPase activity
XppCFBP6546P_RS03740	COG4974	Belongs to the 'phage' integrase family
XppCFBP6546P_RS03750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XppCFBP6546P_RS03755	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XppCFBP6546P_RS03755	COG0047	phosphoribosylformylglycinamidine synthase activity
XppCFBP6546P_RS03760	COG5295	Hep Hag repeat protein
XppCFBP6546P_RS03765	COG1404	Belongs to the peptidase S8 family
XppCFBP6546P_RS03770	COG5295	Hep Hag repeat protein
XppCFBP6546P_RS03775	COG1404	Belongs to the peptidase S8 family
XppCFBP6546P_RS03780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XppCFBP6546P_RS03785	COG1459	type II secretion system
XppCFBP6546P_RS03790	COG2165	general secretion pathway protein
XppCFBP6546P_RS03795	COG4970	Tfp pilus assembly protein FimT
XppCFBP6546P_RS03800	COG2165	general secretion pathway protein
XppCFBP6546P_RS03805	COG4795	General secretion pathway protein
XppCFBP6546P_RS03810	COG3156	type II secretion system protein K
XppCFBP6546P_RS03815	COG3166	PFAM Fimbrial assembly family protein
XppCFBP6546P_RS03830	COG1450	Type ii and iii secretion system protein
XppCFBP6546P_RS03840	COG2188	Transcriptional regulator
XppCFBP6546P_RS03910	COG1215	transferase activity, transferring glycosyl groups
XppCFBP6546P_RS03915	COG1215	transferase activity, transferring glycosyl groups
XppCFBP6546P_RS03920	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XppCFBP6546P_RS03945	COG0242	peptide deformylase activity
XppCFBP6546P_RS03950	COG0488	(ABC) transporter
XppCFBP6546P_RS03960	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XppCFBP6546P_RS03965	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XppCFBP6546P_RS03975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XppCFBP6546P_RS03975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XppCFBP6546P_RS03995	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XppCFBP6546P_RS04000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XppCFBP6546P_RS04005	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XppCFBP6546P_RS04020	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XppCFBP6546P_RS04025	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XppCFBP6546P_RS04035	COG2205	protein histidine kinase activity
XppCFBP6546P_RS04040	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_RS04050	COG0277	FAD linked oxidase domain protein
XppCFBP6546P_RS04055	COG1988	membrane-bound metal-dependent
XppCFBP6546P_RS04060	COG0792	nuclease activity
XppCFBP6546P_RS04100	COG3116	cell division
XppCFBP6546P_RS04110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XppCFBP6546P_RS04115	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XppCFBP6546P_RS04120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XppCFBP6546P_RS04130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XppCFBP6546P_RS04135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XppCFBP6546P_RS04140	COG1181	Belongs to the D-alanine--D-alanine ligase family
XppCFBP6546P_RS04145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XppCFBP6546P_RS04160	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XppCFBP6546P_RS04170	COG0739	heme binding
XppCFBP6546P_RS04175	COG0653	protein targeting
XppCFBP6546P_RS04180	COG0494	nUDIX hydrolase
XppCFBP6546P_RS04190	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XppCFBP6546P_RS04200	COG0604	alcohol dehydrogenase
XppCFBP6546P_RS04200	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS04200	COG3321	synthase
XppCFBP6546P_RS04215	COG0366	Alpha amylase catalytic
XppCFBP6546P_RS04250	COG2226	methyltransferase
XppCFBP6546P_RS04255	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XppCFBP6546P_RS04265	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XppCFBP6546P_RS04305	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XppCFBP6546P_RS04315	COG4106	trans-aconitate 2-methyltransferase activity
XppCFBP6546P_RS04320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XppCFBP6546P_RS04330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XppCFBP6546P_RS04335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XppCFBP6546P_RS04340	COG0667	Aldo Keto reductase
XppCFBP6546P_RS04350	COG4771	TonB-dependent receptor
XppCFBP6546P_RS04370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XppCFBP6546P_RS04375	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XppCFBP6546P_RS04385	COG2175	clavaminate synthase activity
XppCFBP6546P_RS04395	COG4181	ATPase activity
XppCFBP6546P_RS04410	COG0642	Histidine kinase
XppCFBP6546P_RS04420	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XppCFBP6546P_RS04430	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
XppCFBP6546P_RS04440	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XppCFBP6546P_RS04445	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XppCFBP6546P_RS04460	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XppCFBP6546P_RS04465	COG2967	ApaG domain
XppCFBP6546P_RS04470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XppCFBP6546P_RS04475	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XppCFBP6546P_RS04480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XppCFBP6546P_RS04485	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XppCFBP6546P_RS04495	COG0123	including yeast histone deacetylase and acetoin utilization protein
XppCFBP6546P_RS04500	COG2096	Adenosyltransferase
XppCFBP6546P_RS04510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XppCFBP6546P_RS04515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XppCFBP6546P_RS04545	COG3384	dioxygenase
XppCFBP6546P_RS04550	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS04555	COG0318	PFAM AMP-dependent synthetase and ligase
XppCFBP6546P_RS04565	COG1024	Enoyl-CoA hydratase
XppCFBP6546P_RS04585	COG3386	PFAM SMP-30 Gluconolaconase
XppCFBP6546P_RS04595	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XppCFBP6546P_RS04620	COG0697	spore germination
XppCFBP6546P_RS04630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XppCFBP6546P_RS04655	COG2197	response regulator
XppCFBP6546P_RS04665	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XppCFBP6546P_RS04680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XppCFBP6546P_RS04685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XppCFBP6546P_RS04690	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS04695	COG3634	alkyl hydroperoxide reductase activity
XppCFBP6546P_RS04705	COG2890	protein-(glutamine-N5) methyltransferase activity
XppCFBP6546P_RS04725	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XppCFBP6546P_RS04725	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XppCFBP6546P_RS04765	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XppCFBP6546P_RS04780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XppCFBP6546P_RS04785	COG1404	Belongs to the peptidase S8 family
XppCFBP6546P_RS04790	COG1404	Belongs to the peptidase S8 family
XppCFBP6546P_RS04795	COG1404	Belongs to the peptidase S8 family
XppCFBP6546P_RS04800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XppCFBP6546P_RS04825	COG1295	ribonuclease BN
XppCFBP6546P_RS04830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XppCFBP6546P_RS04835	COG1254	Belongs to the acylphosphatase family
XppCFBP6546P_RS04850	COG0521	Mo-molybdopterin cofactor biosynthetic process
XppCFBP6546P_RS04860	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XppCFBP6546P_RS04865	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XppCFBP6546P_RS04875	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XppCFBP6546P_RS04880	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XppCFBP6546P_RS04890	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XppCFBP6546P_RS04895	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XppCFBP6546P_RS04900	COG0193	aminoacyl-tRNA hydrolase activity
XppCFBP6546P_RS04905	COG0012	GTP binding
XppCFBP6546P_RS04925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XppCFBP6546P_RS04940	COG0250	Participates in transcription elongation, termination and antitermination
XppCFBP6546P_RS04945	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XppCFBP6546P_RS04950	COG0081	regulation of translation
XppCFBP6546P_RS04955	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XppCFBP6546P_RS04965	COG0085	RNA polymerase activity
XppCFBP6546P_RS04970	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XppCFBP6546P_RS04975	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XppCFBP6546P_RS04980	COG0049	tRNA binding
XppCFBP6546P_RS04985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XppCFBP6546P_RS04990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XppCFBP6546P_RS05005	COG3328	transposase activity
XppCFBP6546P_RS05010	COG0051	transcription antitermination factor activity, RNA binding
XppCFBP6546P_RS05015	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XppCFBP6546P_RS05020	COG0088	Forms part of the polypeptide exit tunnel
XppCFBP6546P_RS05025	COG0089	rRNA binding
XppCFBP6546P_RS05030	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XppCFBP6546P_RS05035	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XppCFBP6546P_RS05045	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XppCFBP6546P_RS05050	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XppCFBP6546P_RS05055	COG0255	Belongs to the universal ribosomal protein uL29 family
XppCFBP6546P_RS05060	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XppCFBP6546P_RS05070	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XppCFBP6546P_RS05075	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XppCFBP6546P_RS05085	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XppCFBP6546P_RS05090	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XppCFBP6546P_RS05095	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XppCFBP6546P_RS05105	COG1841	ribosomal large subunit assembly
XppCFBP6546P_RS05110	COG0200	Binds to the 23S rRNA
XppCFBP6546P_RS05115	COG0201	protein transport
XppCFBP6546P_RS05140	COG0203	ribosomal protein L17
XppCFBP6546P_RS05145	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XppCFBP6546P_RS05160	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XppCFBP6546P_RS05170	COG0154	amidase activity
XppCFBP6546P_RS05180	COG1217	gtp-binding protein TYPA
XppCFBP6546P_RS05185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XppCFBP6546P_RS05190	COG0039	L-malate dehydrogenase activity
XppCFBP6546P_RS05195	COG0625	glutathione transferase activity
XppCFBP6546P_RS05210	COG0446	pyridine nucleotide-disulphide oxidoreductase
XppCFBP6546P_RS05210	COG1902	pentaerythritol trinitrate reductase activity
XppCFBP6546P_RS05215	COG0604	alcohol dehydrogenase
XppCFBP6546P_RS05220	COG3328	transposase activity
XppCFBP6546P_RS05225	COG3039	Transposase
XppCFBP6546P_RS05230	COG2885	chlorophyll binding
XppCFBP6546P_RS05250	COG0156	8-amino-7-oxononanoate synthase activity
XppCFBP6546P_RS05255	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XppCFBP6546P_RS05260	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XppCFBP6546P_RS05265	COG4208	sulfate ABC transporter
XppCFBP6546P_RS05270	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XppCFBP6546P_RS05280	COG3328	transposase activity
XppCFBP6546P_RS05305	COG0406	alpha-ribazole phosphatase activity
XppCFBP6546P_RS05315	COG0285	dihydrofolate synthase activity
XppCFBP6546P_RS05335	COG2833	Protein of unknown function (DUF455)
XppCFBP6546P_RS05350	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XppCFBP6546P_RS05355	COG0671	phosphoesterase, PA-phosphatase related
XppCFBP6546P_RS05360	COG0438	transferase activity, transferring glycosyl groups
XppCFBP6546P_RS05370	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XppCFBP6546P_RS05385	COG4783	chaperone-mediated protein folding
XppCFBP6546P_RS05400	COG0473	3-isopropylmalate dehydrogenase activity
XppCFBP6546P_RS05440	COG3328	transposase activity
XppCFBP6546P_RS05455	COG0544	peptidyl-prolyl cis-trans isomerase activity
XppCFBP6546P_RS05465	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XppCFBP6546P_RS05495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XppCFBP6546P_RS05505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XppCFBP6546P_RS05515	COG0328	RNA-DNA hybrid ribonuclease activity
XppCFBP6546P_RS05520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XppCFBP6546P_RS05525	COG0631	protein serine/threonine phosphatase activity
XppCFBP6546P_RS05550	COG0859	PFAM glycosyl transferase family 9
XppCFBP6546P_RS05555	COG3642	lipopolysaccharide core region biosynthetic process
XppCFBP6546P_RS05560	COG1234	tRNA 3'-trailer cleavage
XppCFBP6546P_RS05565	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XppCFBP6546P_RS05575	COG0315	cyclic pyranopterin monophosphate synthase activity
XppCFBP6546P_RS05580	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XppCFBP6546P_RS05585	COG0314	molybdopterin synthase activity
XppCFBP6546P_RS05605	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XppCFBP6546P_RS05610	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XppCFBP6546P_RS05615	COG0537	adenosine 5'-monophosphoramidase activity
XppCFBP6546P_RS05635	COG0714	Associated with various cellular activities
XppCFBP6546P_RS05645	COG0424	maF-like protein
XppCFBP6546P_RS05650	COG1399	metal-binding, possibly nucleic acid-binding protein
XppCFBP6546P_RS05655	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XppCFBP6546P_RS05660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XppCFBP6546P_RS05675	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS05690	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XppCFBP6546P_RS05695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XppCFBP6546P_RS05725	COG3829	transcription factor binding
XppCFBP6546P_RS05770	COG2373	Large extracellular alpha-helical protein
XppCFBP6546P_RS05790	COG3852	Histidine kinase
XppCFBP6546P_RS05795	COG4953	penicillin-binding protein 1C
XppCFBP6546P_RS05805	COG0678	peroxiredoxin activity
XppCFBP6546P_RS05825	COG0330	HflC and HflK could
XppCFBP6546P_RS05830	COG0330	HflC and HflK could
XppCFBP6546P_RS05840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XppCFBP6546P_RS05845	COG0308	aminopeptidase N
XppCFBP6546P_RS05855	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS05860	COG1309	transcriptional regulator
XppCFBP6546P_RS05885	COG3328	transposase activity
XppCFBP6546P_RS05915	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XppCFBP6546P_RS05925	COG3387	PFAM Glycoside hydrolase 15-related
XppCFBP6546P_RS05930	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS05935	COG3537	Alpha-1,2-mannosidase
XppCFBP6546P_RS05955	COG0492	ferredoxin-NADP+ reductase activity
XppCFBP6546P_RS05985	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XppCFBP6546P_RS05990	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XppCFBP6546P_RS05995	COG2080	2 iron, 2 sulfur cluster binding
XppCFBP6546P_RS06030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XppCFBP6546P_RS06065	COG1297	OPT oligopeptide transporter protein
XppCFBP6546P_RS06090	COG0823	Involved in the tonB-independent uptake of proteins
XppCFBP6546P_RS06090	COG1506	peptidase
XppCFBP6546P_RS06120	COG2207	Transcriptional regulator
XppCFBP6546P_RS06120	COG1917	Cupin 2, conserved barrel domain protein
XppCFBP6546P_RS06130	COG3328	transposase activity
XppCFBP6546P_RS06140	COG0753	catalase activity
XppCFBP6546P_RS06145	COG0656	L-ascorbic acid biosynthetic process
XppCFBP6546P_RS06155	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XppCFBP6546P_RS06155	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XppCFBP6546P_RS06180	COG2814	Major facilitator Superfamily
XppCFBP6546P_RS06210	COG2194	sulfuric ester hydrolase activity
XppCFBP6546P_RS06225	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_RS06230	COG0642	Histidine kinase
XppCFBP6546P_RS06240	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XppCFBP6546P_RS06245	COG2894	cell division
XppCFBP6546P_RS06250	COG0850	regulation of cytokinetic process
XppCFBP6546P_RS06260	COG4585	Histidine kinase
XppCFBP6546P_RS06265	COG2197	response regulator
XppCFBP6546P_RS06280	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XppCFBP6546P_RS06305	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XppCFBP6546P_RS06315	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XppCFBP6546P_RS06330	COG1595	DNA-templated transcription, initiation
XppCFBP6546P_RS06340	COG1946	Acyl-CoA thioesterase
XppCFBP6546P_RS06355	COG0824	Thioesterase
XppCFBP6546P_RS06360	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XppCFBP6546P_RS06365	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XppCFBP6546P_RS06370	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XppCFBP6546P_RS06375	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XppCFBP6546P_RS06380	COG0268	Binds directly to 16S ribosomal RNA
XppCFBP6546P_RS06390	COG0196	riboflavin kinase activity
XppCFBP6546P_RS06395	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XppCFBP6546P_RS06400	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XppCFBP6546P_RS06405	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XppCFBP6546P_RS06420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XppCFBP6546P_RS06425	COG1845	cytochrome c oxidase, subunit III
XppCFBP6546P_RS06430	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XppCFBP6546P_RS06445	COG3152	Membrane
XppCFBP6546P_RS06455	COG2207	Transcriptional regulator
XppCFBP6546P_RS06460	COG0326	Molecular chaperone. Has ATPase activity
XppCFBP6546P_RS06470	COG1366	Belongs to the anti-sigma-factor antagonist family
XppCFBP6546P_RS06475	COG1366	Belongs to the anti-sigma-factor antagonist family
XppCFBP6546P_RS06505	COG4771	TonB-dependent receptor
XppCFBP6546P_RS06515	COG5507	3-demethylubiquinone-9 3-methyltransferase
XppCFBP6546P_RS06520	COG2205	protein histidine kinase activity
XppCFBP6546P_RS06530	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XppCFBP6546P_RS06535	COG3437	response regulator, receiver
XppCFBP6546P_RS06535	COG3850	Histidine kinase
XppCFBP6546P_RS06535	COG4999	Histidine kinase
XppCFBP6546P_RS06535	COG2205	protein histidine kinase activity
XppCFBP6546P_RS06540	COG0784	Response regulator, receiver
XppCFBP6546P_RS06540	COG4191	Histidine kinase
XppCFBP6546P_RS06565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XppCFBP6546P_RS06575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XppCFBP6546P_RS06580	COG0228	four-way junction DNA binding
XppCFBP6546P_RS06585	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XppCFBP6546P_RS06590	COG0336	Belongs to the RNA methyltransferase TrmD family
XppCFBP6546P_RS06595	COG0335	large ribosomal subunit rRNA binding
XppCFBP6546P_RS06600	COG0534	Mate efflux family protein
XppCFBP6546P_RS06625	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XppCFBP6546P_RS06635	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XppCFBP6546P_RS06675	COG3250	beta-galactosidase activity
XppCFBP6546P_RS06680	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XppCFBP6546P_RS06700	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6546P_RS06730	COG0457	Tetratricopeptide repeat
XppCFBP6546P_RS06740	COG0457	Tetratricopeptide repeat
XppCFBP6546P_RS06750	COG1024	Enoyl-CoA hydratase
XppCFBP6546P_RS06750	COG1250	3-hydroxyacyl-CoA dehydrogenase
XppCFBP6546P_RS06765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XppCFBP6546P_RS06770	COG0481	GTPase activity
XppCFBP6546P_RS06785	COG0571	ribonuclease III activity
XppCFBP6546P_RS06790	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XppCFBP6546P_RS06795	COG1381	Involved in DNA repair and RecF pathway recombination
XppCFBP6546P_RS06805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XppCFBP6546P_RS06810	COG2954	triphosphatase activity
XppCFBP6546P_RS06815	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XppCFBP6546P_RS06820	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XppCFBP6546P_RS06825	COG3046	protein related to deoxyribodipyrimidine photolyase
XppCFBP6546P_RS06830	COG1472	Belongs to the glycosyl hydrolase 3 family
XppCFBP6546P_RS06835	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XppCFBP6546P_RS06840	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XppCFBP6546P_RS06845	COG1278	Cold shock
XppCFBP6546P_RS06850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XppCFBP6546P_RS06860	COG1201	RNA secondary structure unwinding
XppCFBP6546P_RS06865	COG1793	dna ligase
XppCFBP6546P_RS06875	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XppCFBP6546P_RS06875	COG1793	dna ligase
XppCFBP6546P_RS06910	COG0183	Belongs to the thiolase family
XppCFBP6546P_RS06930	COG1451	nucleotide metabolic process
XppCFBP6546P_RS06935	COG5487	UPF0391 membrane protein
XppCFBP6546P_RS06945	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XppCFBP6546P_RS06965	COG1077	Cell shape determining protein MreB Mrl
XppCFBP6546P_RS06970	COG1047	Peptidyl-prolyl cis-trans
XppCFBP6546P_RS06980	COG2824	Alkylphosphonate utilization operon protein PhnA
XppCFBP6546P_RS06990	COG1902	pentaerythritol trinitrate reductase activity
XppCFBP6546P_RS06995	COG2814	Major facilitator Superfamily
XppCFBP6546P_RS07030	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XppCFBP6546P_RS07030	COG0392	lysyltransferase activity
XppCFBP6546P_RS07040	COG0251	oxidation-reduction process
XppCFBP6546P_RS07045	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XppCFBP6546P_RS07060	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XppCFBP6546P_RS07085	COG1595	DNA-templated transcription, initiation
XppCFBP6546P_RS07100	COG2878	Part of a membrane complex involved in electron transport
XppCFBP6546P_RS07110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XppCFBP6546P_RS07110	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XppCFBP6546P_RS07130	COG0346	lactoylglutathione lyase activity
XppCFBP6546P_RS07145	COG0833	amino acid
XppCFBP6546P_RS07150	COG2040	homocysteine
XppCFBP6546P_RS07160	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XppCFBP6546P_RS07180	COG1695	Transcriptional regulator
XppCFBP6546P_RS07200	COG1981	membrane
XppCFBP6546P_RS07215	COG0825	malonyl-CoA metabolic process
XppCFBP6546P_RS07230	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XppCFBP6546P_RS07235	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XppCFBP6546P_RS07240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XppCFBP6546P_RS07245	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XppCFBP6546P_RS07260	COG0750	zinc metalloprotease
XppCFBP6546P_RS07265	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XppCFBP6546P_RS07270	COG0575	Belongs to the CDS family
XppCFBP6546P_RS07275	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XppCFBP6546P_RS07280	COG0233	cytoplasmic translational termination
XppCFBP6546P_RS07285	COG0528	UMP kinase activity
XppCFBP6546P_RS07295	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XppCFBP6546P_RS07300	COG0052	Belongs to the universal ribosomal protein uS2 family
XppCFBP6546P_RS07340	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XppCFBP6546P_RS07350	COG1393	Belongs to the ArsC family
XppCFBP6546P_RS07355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XppCFBP6546P_RS07365	COG0367	asparagine synthase
XppCFBP6546P_RS07375	COG4774	siderophore transport
XppCFBP6546P_RS07475	COG1566	PFAM secretion protein HlyD family protein
XppCFBP6546P_RS07480	COG2814	Major facilitator Superfamily
XppCFBP6546P_RS07510	COG3104	oligopeptide transport
XppCFBP6546P_RS07540	COG0339	signal peptide processing
XppCFBP6546P_RS07545	COG0386	Belongs to the glutathione peroxidase family
XppCFBP6546P_RS07605	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XppCFBP6546P_RS07610	COG0084	hydrolase, TatD family'
XppCFBP6546P_RS07625	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6546P_RS07640	COG0367	asparagine synthase
XppCFBP6546P_RS07650	COG0305	Participates in initiation and elongation during chromosome replication
XppCFBP6546P_RS07655	COG0415	Belongs to the DNA photolyase family
XppCFBP6546P_RS07665	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS07710	COG3706	GGDEF domain
XppCFBP6546P_RS07735	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XppCFBP6546P_RS07750	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XppCFBP6546P_RS07760	COG0497	DNA recombination
XppCFBP6546P_RS07765	COG1420	regulation of RNA biosynthetic process
XppCFBP6546P_RS07770	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XppCFBP6546P_RS07775	COG0443	Heat shock 70 kDa protein
XppCFBP6546P_RS07780	COG0484	heat shock protein binding
XppCFBP6546P_RS07785	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XppCFBP6546P_RS07815	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS07820	COG1132	(ABC) transporter
XppCFBP6546P_RS07855	COG2850	peptidyl-arginine hydroxylation
XppCFBP6546P_RS07875	COG1253	flavin adenine dinucleotide binding
XppCFBP6546P_RS07905	COG1131	(ABC) transporter
XppCFBP6546P_RS07910	COG1725	Transcriptional regulator
XppCFBP6546P_RS07920	COG0386	Belongs to the glutathione peroxidase family
XppCFBP6546P_RS07935	COG2900	Belongs to the SlyX family
XppCFBP6546P_RS07965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XppCFBP6546P_RS07975	COG0646	methionine synthase
XppCFBP6546P_RS07975	COG1410	methionine synthase
XppCFBP6546P_RS07980	COG0646	methionine synthase
XppCFBP6546P_RS07980	COG1410	methionine synthase
XppCFBP6546P_RS07985	COG2226	methyltransferase
XppCFBP6546P_RS07990	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6546P_RS07995	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6546P_RS08010	COG0557	exoribonuclease II activity
XppCFBP6546P_RS08020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XppCFBP6546P_RS08030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XppCFBP6546P_RS08040	COG0704	Plays a role in the regulation of phosphate uptake
XppCFBP6546P_RS08045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XppCFBP6546P_RS08050	COG0581	inorganic phosphate transmembrane transporter activity
XppCFBP6546P_RS08055	COG0573	inorganic phosphate transmembrane transporter activity
XppCFBP6546P_RS08060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XppCFBP6546P_RS08085	COG0659	secondary active sulfate transmembrane transporter activity
XppCFBP6546P_RS08105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XppCFBP6546P_RS08105	COG4651	solute:proton antiporter activity
XppCFBP6546P_RS08135	COG0488	(ABC) transporter
XppCFBP6546P_RS08155	COG2755	lipolytic protein G-D-S-L family
XppCFBP6546P_RS08155	COG0657	acetylesterase activity
XppCFBP6546P_RS08175	COG0477	Major facilitator Superfamily
XppCFBP6546P_RS08190	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XppCFBP6546P_RS08205	COG0217	transcriptional regulatory protein
XppCFBP6546P_RS08210	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XppCFBP6546P_RS08215	COG0632	four-way junction helicase activity
XppCFBP6546P_RS08220	COG3158	transport of potassium into the cell
XppCFBP6546P_RS08230	COG2255	four-way junction helicase activity
XppCFBP6546P_RS08235	COG0824	Thioesterase
XppCFBP6546P_RS08245	COG0848	biopolymer transport protein
XppCFBP6546P_RS08255	COG0823	Involved in the tonB-independent uptake of proteins
XppCFBP6546P_RS08260	COG2885	chlorophyll binding
XppCFBP6546P_RS08270	COG0602	queuosine metabolic process
XppCFBP6546P_RS08280	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XppCFBP6546P_RS08285	COG3920	Histidine kinase
XppCFBP6546P_RS08305	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS08340	COG0514	ATP-dependent DNA helicase (RecQ)
XppCFBP6546P_RS08345	COG0783	Belongs to the Dps family
XppCFBP6546P_RS08350	COG1643	Atp-dependent helicase
XppCFBP6546P_RS08360	COG3328	transposase activity
XppCFBP6546P_RS08370	COG0837	glucose binding
XppCFBP6546P_RS08385	COG0535	radical SAM domain protein
XppCFBP6546P_RS08390	COG0535	radical SAM domain protein
XppCFBP6546P_RS08395	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XppCFBP6546P_RS08400	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XppCFBP6546P_RS08410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XppCFBP6546P_RS08420	COG1215	transferase activity, transferring glycosyl groups
XppCFBP6546P_RS08425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XppCFBP6546P_RS08435	COG1199	ATP-dependent helicase activity
XppCFBP6546P_RS08445	COG1397	ADP-ribosylglycohydrolase
XppCFBP6546P_RS08455	COG0189	ligase activity
XppCFBP6546P_RS08470	COG0835	chemotaxis
XppCFBP6546P_RS08475	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS08480	COG0784	Response regulator, receiver
XppCFBP6546P_RS08480	COG0643	Histidine kinase
XppCFBP6546P_RS08480	COG2198	Histidine kinase
XppCFBP6546P_RS08505	COG1446	asparaginase
XppCFBP6546P_RS08510	COG3142	Participates in the control of copper homeostasis
XppCFBP6546P_RS08545	COG3537	Alpha-1,2-mannosidase
XppCFBP6546P_RS08555	COG1472	Belongs to the glycosyl hydrolase 3 family
XppCFBP6546P_RS08565	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XppCFBP6546P_RS08570	COG1388	LysM domain
XppCFBP6546P_RS08570	COG3858	chitin binding
XppCFBP6546P_RS08590	COG4787	bacterial-type flagellum-dependent cell motility
XppCFBP6546P_RS08600	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XppCFBP6546P_RS08605	COG1558	bacterial-type flagellum-dependent cell motility
XppCFBP6546P_RS08615	COG0835	chemotaxis
XppCFBP6546P_RS08615	COG0784	Response regulator, receiver
XppCFBP6546P_RS08635	COG5002	protein histidine kinase activity
XppCFBP6546P_RS08645	COG4585	Histidine kinase
XppCFBP6546P_RS08665	COG2915	High frequency lysogenization protein hflD homolog
XppCFBP6546P_RS08670	COG0482	sulfurtransferase activity
XppCFBP6546P_RS08690	COG0542	response to heat
XppCFBP6546P_RS08700	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XppCFBP6546P_RS08710	COG0492	ferredoxin-NADP+ reductase activity
XppCFBP6546P_RS08715	COG1674	ftsk spoiiie
XppCFBP6546P_RS08725	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XppCFBP6546P_RS08735	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XppCFBP6546P_RS08740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XppCFBP6546P_RS08745	COG0183	Belongs to the thiolase family
XppCFBP6546P_RS08750	COG1250	3-hydroxyacyl-CoA dehydrogenase
XppCFBP6546P_RS08750	COG1024	Enoyl-CoA hydratase
XppCFBP6546P_RS08765	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XppCFBP6546P_RS08785	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XppCFBP6546P_RS08790	COG1160	GTP binding
XppCFBP6546P_RS08795	COG0303	'Molybdopterin
XppCFBP6546P_RS08800	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XppCFBP6546P_RS08835	COG0708	Exodeoxyribonuclease III
XppCFBP6546P_RS08845	COG0303	'Molybdopterin
XppCFBP6546P_RS08850	COG0746	molybdenum cofactor guanylyltransferase activity
XppCFBP6546P_RS08875	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XppCFBP6546P_RS08875	COG1648	precorrin-2 dehydrogenase activity
XppCFBP6546P_RS08885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XppCFBP6546P_RS08890	COG2223	nitrite transmembrane transporter activity
XppCFBP6546P_RS08895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XppCFBP6546P_RS08905	COG0243	molybdopterin cofactor binding
XppCFBP6546P_RS08925	COG3685	Protein conserved in bacteria
XppCFBP6546P_RS08945	COG5001	Diguanylate cyclase
XppCFBP6546P_RS08955	COG4566	intracellular signal transduction
XppCFBP6546P_RS09005	COG3328	transposase activity
XppCFBP6546P_RS09020	COG3039	Transposase
XppCFBP6546P_RS09025	COG3328	transposase activity
XppCFBP6546P_RS09105	COG3328	transposase activity
XppCFBP6546P_RS09115	COG1073	alpha beta
XppCFBP6546P_RS09115	COG2226	methyltransferase
XppCFBP6546P_RS09130	COG0363	glucosamine-6-phosphate deaminase activity
XppCFBP6546P_RS09225	COG3328	transposase activity
XppCFBP6546P_RS09270	COG3328	transposase activity
XppCFBP6546P_RS09290	COG1192	Involved in chromosome partitioning
XppCFBP6546P_RS09335	COG3318	Belongs to the UPF0149 family
XppCFBP6546P_RS09335	COG3012	SEC-C Motif Domain Protein
XppCFBP6546P_RS09370	COG3328	transposase activity
XppCFBP6546P_RS09405	COG1309	transcriptional regulator
XppCFBP6546P_RS09420	COG2154	pterin-4-alpha-carbinolamine dehydratase
XppCFBP6546P_RS09430	COG0428	transporter
XppCFBP6546P_RS09435	COG3064	Membrane
XppCFBP6546P_RS09445	COG1530	ribonuclease E activity
XppCFBP6546P_RS09450	COG3039	Transposase
XppCFBP6546P_RS09460	COG1054	Belongs to the UPF0176 family
XppCFBP6546P_RS09480	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XppCFBP6546P_RS09505	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XppCFBP6546P_RS09510	COG0322	excinuclease ABC activity
XppCFBP6546P_RS09520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XppCFBP6546P_RS09525	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XppCFBP6546P_RS09530	COG1663	tetraacyldisaccharide 4'-kinase activity
XppCFBP6546P_RS09535	COG1132	(ABC) transporter
XppCFBP6546P_RS09545	COG0811	peptide transport
XppCFBP6546P_RS09560	COG1136	(ABC) transporter
XppCFBP6546P_RS09565	COG4591	ABC-type transport system involved in lipoprotein release permease component
XppCFBP6546P_RS09575	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XppCFBP6546P_RS09580	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XppCFBP6546P_RS09595	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XppCFBP6546P_RS09610	COG0354	folic acid binding
XppCFBP6546P_RS09620	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XppCFBP6546P_RS09625	COG0837	glucose binding
XppCFBP6546P_RS09630	COG0363	glucosamine-6-phosphate deaminase activity
XppCFBP6546P_RS09635	COG0129	dihydroxy-acid dehydratase activity
XppCFBP6546P_RS09640	COG0800	Aldolase
XppCFBP6546P_RS09705	COG2205	protein histidine kinase activity
XppCFBP6546P_RS09705	COG0784	Response regulator, receiver
XppCFBP6546P_RS09710	COG2183	response to ionizing radiation
XppCFBP6546P_RS09720	COG0723	plastoquinol--plastocyanin reductase activity
XppCFBP6546P_RS09720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP6546P_RS09735	COG3243	poly(R)-hydroxyalkanoic acid synthase
XppCFBP6546P_RS09745	COG1183	phosphatidylcholine synthase activity
XppCFBP6546P_RS09750	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS09765	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XppCFBP6546P_RS09780	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XppCFBP6546P_RS09795	COG1914	H( )-stimulated, divalent metal cation uptake system
XppCFBP6546P_RS09815	COG2814	Major facilitator Superfamily
XppCFBP6546P_RS09830	COG1335	isochorismatase
XppCFBP6546P_RS09845	COG2197	response regulator
XppCFBP6546P_RS09870	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS09875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XppCFBP6546P_RS09880	COG3002	Belongs to the UPF0753 family
XppCFBP6546P_RS09890	COG0604	alcohol dehydrogenase
XppCFBP6546P_RS09895	COG3384	dioxygenase
XppCFBP6546P_RS09910	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
XppCFBP6546P_RS09950	COG0519	Catalyzes the synthesis of GMP from XMP
XppCFBP6546P_RS09950	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XppCFBP6546P_RS09960	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XppCFBP6546P_RS09970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XppCFBP6546P_RS09970	COG0475	glutathione-regulated potassium exporter activity
XppCFBP6546P_RS09975	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XppCFBP6546P_RS09985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XppCFBP6546P_RS09990	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XppCFBP6546P_RS10000	COG0776	regulation of translation
XppCFBP6546P_RS10005	COG0539	negative regulation of cytoplasmic translation
XppCFBP6546P_RS10010	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XppCFBP6546P_RS10025	COG2957	Belongs to the agmatine deiminase family
XppCFBP6546P_RS10030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XppCFBP6546P_RS10055	COG0395	ABC-type sugar transport system, permease component
XppCFBP6546P_RS10060	COG1175	transmembrane transport
XppCFBP6546P_RS10090	COG2350	Protein conserved in bacteria
XppCFBP6546P_RS10095	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XppCFBP6546P_RS10100	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XppCFBP6546P_RS10105	COG1187	pseudouridine synthase activity
XppCFBP6546P_RS10120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XppCFBP6546P_RS10125	COG0436	Aminotransferase
XppCFBP6546P_RS10130	COG4133	protoheme IX ABC transporter activity
XppCFBP6546P_RS10150	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XppCFBP6546P_RS10175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XppCFBP6546P_RS10185	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XppCFBP6546P_RS10190	COG4988	ABC transporter
XppCFBP6546P_RS10200	COG1294	oxidase, subunit
XppCFBP6546P_RS10230	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XppCFBP6546P_RS10235	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XppCFBP6546P_RS10245	COG0165	Argininosuccinate lyase
XppCFBP6546P_RS10250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XppCFBP6546P_RS10260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XppCFBP6546P_RS10265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XppCFBP6546P_RS10275	COG0137	argininosuccinate synthase activity
XppCFBP6546P_RS10280	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XppCFBP6546P_RS10290	COG0215	cysteine-tRNA ligase activity
XppCFBP6546P_RS10295	COG2166	iron-sulfur cluster assembly
XppCFBP6546P_RS10310	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XppCFBP6546P_RS10315	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XppCFBP6546P_RS10340	COG4302	ethanolamine ammonia-lyase activity
XppCFBP6546P_RS10370	COG3039	Transposase
XppCFBP6546P_RS10400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XppCFBP6546P_RS10405	COG0402	S-adenosylhomocysteine deaminase activity
XppCFBP6546P_RS10415	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XppCFBP6546P_RS10420	COG1509	lysine 2,3-aminomutase activity
XppCFBP6546P_RS10425	COG3300	MHYT domain
XppCFBP6546P_RS10425	COG5001	Diguanylate cyclase
XppCFBP6546P_RS10440	COG0483	inositol monophosphate 1-phosphatase activity
XppCFBP6546P_RS10445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XppCFBP6546P_RS10460	COG0488	(ABC) transporter
XppCFBP6546P_RS10465	COG0513	Belongs to the DEAD box helicase family
XppCFBP6546P_RS10470	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XppCFBP6546P_RS10475	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XppCFBP6546P_RS10490	COG0625	glutathione transferase activity
XppCFBP6546P_RS10500	COG4681	YaeQ
XppCFBP6546P_RS10505	COG2081	HI0933 family
XppCFBP6546P_RS10515	COG0501	Belongs to the peptidase M48B family
XppCFBP6546P_RS10520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XppCFBP6546P_RS10525	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS10550	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XppCFBP6546P_RS10555	COG0860	N-Acetylmuramoyl-L-alanine amidase
XppCFBP6546P_RS10560	COG0802	atpase or kinase
XppCFBP6546P_RS10565	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XppCFBP6546P_RS10565	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XppCFBP6546P_RS10570	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XppCFBP6546P_RS10575	COG1570	exodeoxyribonuclease VII activity
XppCFBP6546P_RS10585	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XppCFBP6546P_RS10630	COG0835	chemotaxis
XppCFBP6546P_RS10635	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS10640	COG2094	Belongs to the DNA glycosylase MPG family
XppCFBP6546P_RS10645	COG1201	RNA secondary structure unwinding
XppCFBP6546P_RS10665	COG2969	positive regulation of protein catabolic process
XppCFBP6546P_RS10670	COG0625	glutathione transferase activity
XppCFBP6546P_RS10675	COG2857	Cytochrome c1
XppCFBP6546P_RS10680	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XppCFBP6546P_RS10685	COG0723	plastoquinol--plastocyanin reductase activity
XppCFBP6546P_RS10690	COG0741	lytic transglycosylase activity
XppCFBP6546P_RS10705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XppCFBP6546P_RS10710	COG1702	phosphate starvation-inducible protein PhoH
XppCFBP6546P_RS10720	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XppCFBP6546P_RS10730	COG4535	Mg2 and Co2 transporter CorC
XppCFBP6546P_RS10745	COG1012	belongs to the aldehyde dehydrogenase family
XppCFBP6546P_RS10750	COG1177	transmembrane transport
XppCFBP6546P_RS10755	COG1176	ABC-type spermidine putrescine transport system, permease component I
XppCFBP6546P_RS10760	COG3842	ATPase activity
XppCFBP6546P_RS10780	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XppCFBP6546P_RS10800	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XppCFBP6546P_RS10805	COG0174	glutamine synthetase
XppCFBP6546P_RS10810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP6546P_RS10820	COG2703	oxygen carrier activity
XppCFBP6546P_RS10825	COG0477	Major facilitator Superfamily
XppCFBP6546P_RS10835	COG0243	molybdopterin cofactor binding
XppCFBP6546P_RS10840	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XppCFBP6546P_RS10845	COG2223	nitrite transmembrane transporter activity
XppCFBP6546P_RS10850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XppCFBP6546P_RS10860	COG2733	membrane
XppCFBP6546P_RS10865	COG0784	Response regulator, receiver
XppCFBP6546P_RS10865	COG2205	protein histidine kinase activity
XppCFBP6546P_RS10865	COG5002	protein histidine kinase activity
XppCFBP6546P_RS10875	COG0477	Major facilitator Superfamily
XppCFBP6546P_RS10910	COG2902	Dehydrogenase
XppCFBP6546P_RS10920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6546P_RS10925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP6546P_RS10930	COG1609	Transcriptional regulator
XppCFBP6546P_RS10935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XppCFBP6546P_RS10935	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XppCFBP6546P_RS10940	COG1105	Belongs to the carbohydrate kinase PfkB family
XppCFBP6546P_RS10945	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XppCFBP6546P_RS10945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XppCFBP6546P_RS10960	COG3328	transposase activity
XppCFBP6546P_RS10965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XppCFBP6546P_RS10975	COG1862	Preprotein translocase
XppCFBP6546P_RS10980	COG0343	queuine tRNA-ribosyltransferase activity
XppCFBP6546P_RS10985	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XppCFBP6546P_RS11020	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XppCFBP6546P_RS11025	COG3291	Pkd domain containing protein
XppCFBP6546P_RS11030	COG0405	Gamma-glutamyltransferase
XppCFBP6546P_RS11035	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XppCFBP6546P_RS11045	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XppCFBP6546P_RS11050	COG0742	ribosomal rna small subunit methyltransferase
XppCFBP6546P_RS11055	COG0326	Molecular chaperone. Has ATPase activity
XppCFBP6546P_RS11140	COG3702	type iv secretory pathway
XppCFBP6546P_RS11160	COG2948	multi-organism process
XppCFBP6546P_RS11180	COG3505	Type IV secretory pathway VirD4
XppCFBP6546P_RS11195	COG0556	nucleotide-excision repair
XppCFBP6546P_RS11365	COG3179	chitinase
XppCFBP6546P_RS11410	COG4695	Portal protein
XppCFBP6546P_RS11485	COG3275	phosphorelay sensor kinase activity
XppCFBP6546P_RS11490	COG1611	Belongs to the LOG family
XppCFBP6546P_RS11500	COG2095	MarC family integral membrane protein
XppCFBP6546P_RS11510	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XppCFBP6546P_RS11545	COG1185	polyribonucleotide nucleotidyltransferase activity
XppCFBP6546P_RS11550	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XppCFBP6546P_RS11555	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XppCFBP6546P_RS11560	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XppCFBP6546P_RS11565	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XppCFBP6546P_RS11570	COG0195	Participates in both transcription termination and antitermination
XppCFBP6546P_RS11575	COG0779	Required for maturation of 30S ribosomal subunits
XppCFBP6546P_RS11585	COG1007	ATP synthesis coupled electron transport
XppCFBP6546P_RS11610	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XppCFBP6546P_RS11615	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XppCFBP6546P_RS11625	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XppCFBP6546P_RS11630	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XppCFBP6546P_RS11635	COG0649	NAD binding
XppCFBP6546P_RS11640	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XppCFBP6546P_RS11645	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XppCFBP6546P_RS11650	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XppCFBP6546P_RS11665	COG0149	triose-phosphate isomerase activity
XppCFBP6546P_RS11670	COG4221	oxidoreductase activity
XppCFBP6546P_RS11700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XppCFBP6546P_RS11705	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XppCFBP6546P_RS11710	COG0159	tryptophan synthase activity
XppCFBP6546P_RS11720	COG0133	tryptophan synthase activity
XppCFBP6546P_RS11730	COG0135	phosphoribosylanthranilate isomerase activity
XppCFBP6546P_RS11735	COG0101	tRNA pseudouridine synthase activity
XppCFBP6546P_RS11750	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XppCFBP6546P_RS11755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XppCFBP6546P_RS11760	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XppCFBP6546P_RS11765	COG2890	protein-(glutamine-N5) methyltransferase activity
XppCFBP6546P_RS11775	COG0688	phosphatidylethanolamine metabolic process
XppCFBP6546P_RS11785	COG0433	COG0433 Predicted ATPase
XppCFBP6546P_RS11810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XppCFBP6546P_RS11815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XppCFBP6546P_RS11840	COG0717	Belongs to the dCTP deaminase family
XppCFBP6546P_RS11845	COG0489	protein tyrosine kinase activity
XppCFBP6546P_RS11875	COG3590	peptidase
XppCFBP6546P_RS11900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XppCFBP6546P_RS11905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP6546P_RS11910	COG2311	Membrane
XppCFBP6546P_RS11915	COG1047	Peptidyl-prolyl cis-trans
XppCFBP6546P_RS11920	COG0791	NLP P60 protein
XppCFBP6546P_RS11925	COG0791	NLP P60 protein
XppCFBP6546P_RS11935	COG4106	trans-aconitate 2-methyltransferase activity
XppCFBP6546P_RS11940	COG1301	dicarboxylic acid transport
XppCFBP6546P_RS11945	COG1785	Belongs to the alkaline phosphatase family
XppCFBP6546P_RS11950	COG0037	tRNA processing
XppCFBP6546P_RS11955	COG1722	exodeoxyribonuclease VII activity
XppCFBP6546P_RS11960	COG0142	geranyltranstransferase activity
XppCFBP6546P_RS11965	COG4104	PAAR repeat-containing protein
XppCFBP6546P_RS11975	COG0312	modulator of DNA gyrase
XppCFBP6546P_RS11980	COG3028	Belongs to the UPF0307 family
XppCFBP6546P_RS11985	COG0312	modulator of DNA gyrase
XppCFBP6546P_RS11995	COG3164	Protein of unknown function
XppCFBP6546P_RS12005	COG0424	maF-like protein
XppCFBP6546P_RS12010	COG2968	Membrane
XppCFBP6546P_RS12025	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XppCFBP6546P_RS12040	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XppCFBP6546P_RS12055	COG0495	leucyl-tRNA aminoacylation
XppCFBP6546P_RS12065	COG3118	belongs to the thioredoxin family
XppCFBP6546P_RS12090	COG2155	Conserved Protein
XppCFBP6546P_RS12140	COG1132	(ABC) transporter
XppCFBP6546P_RS12170	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_RS12175	COG5000	phosphorelay sensor kinase activity
XppCFBP6546P_RS12175	COG5002	protein histidine kinase activity
XppCFBP6546P_RS12180	COG0475	glutathione-regulated potassium exporter activity
XppCFBP6546P_RS12190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XppCFBP6546P_RS12210	COG1187	pseudouridine synthase activity
XppCFBP6546P_RS12215	COG5002	protein histidine kinase activity
XppCFBP6546P_RS12215	COG5001	Diguanylate cyclase
XppCFBP6546P_RS12225	COG1595	DNA-templated transcription, initiation
XppCFBP6546P_RS12340	COG0667	Aldo Keto reductase
XppCFBP6546P_RS12345	COG2814	Major facilitator Superfamily
XppCFBP6546P_RS12350	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS12360	COG2207	Transcriptional regulator
XppCFBP6546P_RS12370	COG1309	transcriptional regulator
XppCFBP6546P_RS12380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP6546P_RS12395	COG0735	belongs to the Fur family
XppCFBP6546P_RS12400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XppCFBP6546P_RS12425	COG4452	Inner membrane protein CreD
XppCFBP6546P_RS12445	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_RS12450	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XppCFBP6546P_RS12465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XppCFBP6546P_RS12475	COG0643	Histidine kinase
XppCFBP6546P_RS12475	COG2198	Histidine kinase
XppCFBP6546P_RS12480	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS12485	COG0835	chemotaxis
XppCFBP6546P_RS12490	COG2202	Pas domain
XppCFBP6546P_RS12490	COG2200	EAL domain
XppCFBP6546P_RS12490	COG2199	diguanylate cyclase activity
XppCFBP6546P_RS12495	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XppCFBP6546P_RS12500	COG2201	protein-glutamate methylesterase activity
XppCFBP6546P_RS12510	COG3590	peptidase
XppCFBP6546P_RS12525	COG1515	deoxyribonuclease V activity
XppCFBP6546P_RS12535	COG1741	Belongs to the pirin family
XppCFBP6546P_RS12550	COG1741	Belongs to the pirin family
XppCFBP6546P_RS12555	COG1966	Carbon starvation protein
XppCFBP6546P_RS12560	COG2879	small protein
XppCFBP6546P_RS12595	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XppCFBP6546P_RS12600	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XppCFBP6546P_RS12605	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XppCFBP6546P_RS12610	COG2080	2 iron, 2 sulfur cluster binding
XppCFBP6546P_RS12615	COG3321	synthase
XppCFBP6546P_RS12615	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS12615	COG0604	alcohol dehydrogenase
XppCFBP6546P_RS12620	COG2203	Gaf domain
XppCFBP6546P_RS12620	COG3706	GGDEF domain
XppCFBP6546P_RS12620	COG4251	negative regulation of phosphorylation
XppCFBP6546P_RS12620	COG5001	Diguanylate cyclase
XppCFBP6546P_RS12625	COG0629	single-stranded DNA binding
XppCFBP6546P_RS12630	COG0142	geranyltranstransferase activity
XppCFBP6546P_RS12640	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XppCFBP6546P_RS12655	COG0527	aspartate kinase activity
XppCFBP6546P_RS12660	COG0384	phenazine biosynthesis protein PhzF
XppCFBP6546P_RS12665	COG0384	phenazine biosynthesis protein PhzF
XppCFBP6546P_RS12675	COG1764	response to oxidative stress
XppCFBP6546P_RS12680	COG0540	Belongs to the ATCase OTCase family
XppCFBP6546P_RS12685	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XppCFBP6546P_RS12690	COG1678	Uncharacterized ACR, COG1678
XppCFBP6546P_RS12695	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
XppCFBP6546P_RS12700	COG0519	Catalyzes the synthesis of GMP from XMP
XppCFBP6546P_RS12725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XppCFBP6546P_RS12740	COG0739	heme binding
XppCFBP6546P_RS12760	COG0693	protein deglycase activity
XppCFBP6546P_RS12770	COG1959	2 iron, 2 sulfur cluster binding
XppCFBP6546P_RS12775	COG0719	Fe-S assembly protein
XppCFBP6546P_RS12780	COG0396	ATPase activity
XppCFBP6546P_RS12785	COG0719	Fe-S assembly protein
XppCFBP6546P_RS12790	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XppCFBP6546P_RS12795	COG0456	acetyltransferase
XppCFBP6546P_RS12800	COG2146	nitrite reductase [NAD(P)H] activity
XppCFBP6546P_RS12805	COG4774	siderophore transport
XppCFBP6546P_RS12810	COG3128	pkhd-type hydroxylase
XppCFBP6546P_RS12835	COG3328	transposase activity
XppCFBP6546P_RS12840	COG1477	protein flavinylation
XppCFBP6546P_RS12845	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XppCFBP6546P_RS12855	COG1555	photosystem II stabilization
XppCFBP6546P_RS12875	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XppCFBP6546P_RS12885	COG0628	permease
XppCFBP6546P_RS12895	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XppCFBP6546P_RS12910	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XppCFBP6546P_RS12930	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XppCFBP6546P_RS12935	COG0271	Belongs to the BolA IbaG family
XppCFBP6546P_RS12945	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XppCFBP6546P_RS12955	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XppCFBP6546P_RS12960	COG1137	ATPase activity
XppCFBP6546P_RS12975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XppCFBP6546P_RS12980	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XppCFBP6546P_RS12985	COG1660	Displays ATPase and GTPase activities
XppCFBP6546P_RS12995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XppCFBP6546P_RS13010	COG2239	Acts as a magnesium transporter
XppCFBP6546P_RS13020	COG1294	oxidase, subunit
XppCFBP6546P_RS13070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XppCFBP6546P_RS13070	COG0551	DNA topoisomerase type I activity
XppCFBP6546P_RS13085	COG2951	lytic endotransglycosylase activity
XppCFBP6546P_RS13160	COG1113	amino acid transport
XppCFBP6546P_RS13185	COG2197	response regulator
XppCFBP6546P_RS13190	COG0531	amino acid
XppCFBP6546P_RS13260	COG2814	Major facilitator Superfamily
XppCFBP6546P_RS13265	COG0754	glutathionylspermidine amidase activity
XppCFBP6546P_RS13290	COG1842	Phage shock protein A
XppCFBP6546P_RS13300	COG0259	pyridoxamine-phosphate oxidase activity
XppCFBP6546P_RS13305	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XppCFBP6546P_RS13310	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XppCFBP6546P_RS13320	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XppCFBP6546P_RS13325	COG2814	Major facilitator Superfamily
XppCFBP6546P_RS13350	COG0784	Response regulator, receiver
XppCFBP6546P_RS13350	COG2198	Histidine kinase
XppCFBP6546P_RS13350	COG2205	protein histidine kinase activity
XppCFBP6546P_RS13355	COG2353	YceI-like domain
XppCFBP6546P_RS13375	COG1760	l-serine dehydratase
XppCFBP6546P_RS13385	COG0460	homoserine dehydrogenase
XppCFBP6546P_RS13385	COG0527	aspartate kinase activity
XppCFBP6546P_RS13390	COG0626	cystathionine gamma-synthase activity
XppCFBP6546P_RS13395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XppCFBP6546P_RS13400	COG0739	heme binding
XppCFBP6546P_RS13405	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XppCFBP6546P_RS13410	COG1272	protein, Hemolysin III
XppCFBP6546P_RS13415	COG2982	Protein involved in outer membrane biogenesis
XppCFBP6546P_RS13420	COG0517	IMP dehydrogenase activity
XppCFBP6546P_RS13420	COG0516	GMP reductase activity
XppCFBP6546P_RS13425	COG0463	Glycosyl transferase, family 2
XppCFBP6546P_RS13430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XppCFBP6546P_RS13435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XppCFBP6546P_RS13445	COG4771	TonB-dependent receptor
XppCFBP6546P_RS13450	COG1309	transcriptional regulator
XppCFBP6546P_RS13460	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6546P_RS13485	COG3328	transposase activity
XppCFBP6546P_RS13510	COG0509	glycine decarboxylation via glycine cleavage system
XppCFBP6546P_RS13515	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XppCFBP6546P_RS13525	COG0330	HflC and HflK could
XppCFBP6546P_RS13530	COG1742	UPF0060 membrane protein
XppCFBP6546P_RS13535	COG3956	TIGRFAM MazG family protein
XppCFBP6546P_RS13545	COG0494	nUDIX hydrolase
XppCFBP6546P_RS13555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XppCFBP6546P_RS13560	COG0837	glucose binding
XppCFBP6546P_RS13600	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XppCFBP6546P_RS13605	COG1360	Flagellar Motor Protein
XppCFBP6546P_RS13610	COG1192	Involved in chromosome partitioning
XppCFBP6546P_RS13615	COG0835	chemotaxis
XppCFBP6546P_RS13625	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_RS13635	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS13640	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS13655	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS13665	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS13670	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS13675	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS13680	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS13695	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS13700	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS13705	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS13710	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS13715	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS13725	COG0835	chemotaxis
XppCFBP6546P_RS13735	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS13745	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XppCFBP6546P_RS13750	COG2201	protein-glutamate methylesterase activity
XppCFBP6546P_RS13760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XppCFBP6546P_RS13795	COG0318	PFAM AMP-dependent synthetase and ligase
XppCFBP6546P_RS13800	COG1024	Enoyl-CoA hydratase
XppCFBP6546P_RS13805	COG2205	protein histidine kinase activity
XppCFBP6546P_RS13805	COG2198	Histidine kinase
XppCFBP6546P_RS13805	COG0784	Response regulator, receiver
XppCFBP6546P_RS13810	COG2205	protein histidine kinase activity
XppCFBP6546P_RS13810	COG2198	Histidine kinase
XppCFBP6546P_RS13810	COG0784	Response regulator, receiver
XppCFBP6546P_RS13820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XppCFBP6546P_RS13840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XppCFBP6546P_RS13850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XppCFBP6546P_RS13855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XppCFBP6546P_RS13865	COG0505	Belongs to the CarA family
XppCFBP6546P_RS13870	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XppCFBP6546P_RS13875	COG2258	MOSC domain
XppCFBP6546P_RS13880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XppCFBP6546P_RS13925	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XppCFBP6546P_RS13945	COG0277	FAD linked oxidase domain protein
XppCFBP6546P_RS13950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XppCFBP6546P_RS13960	COG0531	amino acid
XppCFBP6546P_RS13965	COG0531	amino acid
XppCFBP6546P_RS13970	COG0235	Class ii aldolase
XppCFBP6546P_RS13975	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XppCFBP6546P_RS13980	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XppCFBP6546P_RS13995	COG0140	phosphoribosyl-ATP diphosphatase activity
XppCFBP6546P_RS13995	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XppCFBP6546P_RS14000	COG0107	imidazoleglycerol-phosphate synthase activity
XppCFBP6546P_RS14005	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XppCFBP6546P_RS14010	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XppCFBP6546P_RS14015	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XppCFBP6546P_RS14015	COG0131	Imidazoleglycerol-phosphate dehydratase
XppCFBP6546P_RS14020	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XppCFBP6546P_RS14025	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XppCFBP6546P_RS14030	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XppCFBP6546P_RS14040	COG0124	histidyl-tRNA synthetase
XppCFBP6546P_RS14045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XppCFBP6546P_RS14080	COG0460	homoserine dehydrogenase
XppCFBP6546P_RS14080	COG0527	aspartate kinase activity
XppCFBP6546P_RS14085	COG3328	transposase activity
XppCFBP6546P_RS14090	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
XppCFBP6546P_RS14110	COG3328	transposase activity
XppCFBP6546P_RS14145	COG3328	transposase activity
XppCFBP6546P_RS14240	COG0531	amino acid
XppCFBP6546P_RS14255	COG0006	proline dipeptidase activity
XppCFBP6546P_RS14265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XppCFBP6546P_RS14280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP6546P_RS14285	COG3938	Belongs to the proline racemase family
XppCFBP6546P_RS14295	COG0552	protein localization to endoplasmic reticulum
XppCFBP6546P_RS14300	COG1194	a g-specific adenine glycosylase
XppCFBP6546P_RS14320	COG4191	Histidine kinase
XppCFBP6546P_RS14320	COG0784	Response regulator, receiver
XppCFBP6546P_RS14335	COG0322	excinuclease ABC activity
XppCFBP6546P_RS14350	COG3040	lipid binding
XppCFBP6546P_RS14360	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6546P_RS14370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XppCFBP6546P_RS14390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XppCFBP6546P_RS14400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XppCFBP6546P_RS14425	COG0438	transferase activity, transferring glycosyl groups
XppCFBP6546P_RS14435	COG0438	transferase activity, transferring glycosyl groups
XppCFBP6546P_RS14440	COG0438	transferase activity, transferring glycosyl groups
XppCFBP6546P_RS14490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XppCFBP6546P_RS14490	COG0072	phenylalanine-tRNA ligase activity
XppCFBP6546P_RS14495	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XppCFBP6546P_RS14510	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XppCFBP6546P_RS14515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XppCFBP6546P_RS14530	COG2211	Major facilitator Superfamily
XppCFBP6546P_RS14540	COG1082	Xylose isomerase domain protein TIM barrel
XppCFBP6546P_RS14560	COG0366	Alpha amylase catalytic
XppCFBP6546P_RS14565	COG3328	transposase activity
XppCFBP6546P_RS14575	COG1012	belongs to the aldehyde dehydrogenase family
XppCFBP6546P_RS14590	COG0167	dihydroorotate dehydrogenase activity
XppCFBP6546P_RS14595	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XppCFBP6546P_RS14600	COG0697	spore germination
XppCFBP6546P_RS14615	COG0671	phosphoesterase, PA-phosphatase related
XppCFBP6546P_RS14620	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XppCFBP6546P_RS14630	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XppCFBP6546P_RS14635	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XppCFBP6546P_RS14640	COG2203	Gaf domain
XppCFBP6546P_RS14640	COG3706	GGDEF domain
XppCFBP6546P_RS14640	COG4251	negative regulation of phosphorylation
XppCFBP6546P_RS14640	COG5001	Diguanylate cyclase
XppCFBP6546P_RS14650	COG1472	Belongs to the glycosyl hydrolase 3 family
XppCFBP6546P_RS14670	COG0166	Belongs to the GPI family
XppCFBP6546P_RS14675	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XppCFBP6546P_RS14680	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XppCFBP6546P_RS14685	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XppCFBP6546P_RS14710	COG1469	GTP cyclohydrolase I activity
XppCFBP6546P_RS14715	COG0860	N-Acetylmuramoyl-L-alanine amidase
XppCFBP6546P_RS14735	COG0477	Major facilitator Superfamily
XppCFBP6546P_RS14740	COG2115	Belongs to the xylose isomerase family
XppCFBP6546P_RS14745	COG1070	Carbohydrate kinase
XppCFBP6546P_RS14755	COG1501	Belongs to the glycosyl hydrolase 31 family
XppCFBP6546P_RS14800	COG0800	Aldolase
XppCFBP6546P_RS14805	COG4948	Mandelate Racemase Muconate Lactonizing
XppCFBP6546P_RS14815	COG3734	2-keto-3-deoxy-galactonokinase
XppCFBP6546P_RS14820	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XppCFBP6546P_RS14830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XppCFBP6546P_RS14845	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XppCFBP6546P_RS14850	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XppCFBP6546P_RS14865	COG0351	phosphomethylpyrimidine kinase
XppCFBP6546P_RS14890	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS14910	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XppCFBP6546P_RS14915	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XppCFBP6546P_RS14920	COG2137	regulation of response to DNA damage stimulus
XppCFBP6546P_RS14925	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XppCFBP6546P_RS14930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XppCFBP6546P_RS14940	COG1546	Belongs to the CinA family
XppCFBP6546P_RS14945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XppCFBP6546P_RS14955	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XppCFBP6546P_RS14960	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XppCFBP6546P_RS14970	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XppCFBP6546P_RS14975	COG1534	Rna-binding protein
XppCFBP6546P_RS14980	COG3737	Protein of unknown function (DUF498/DUF598)
XppCFBP6546P_RS14990	COG1238	metal cluster binding
XppCFBP6546P_RS14995	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XppCFBP6546P_RS15000	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XppCFBP6546P_RS15005	COG2840	Smr protein MutS2
XppCFBP6546P_RS15010	COG0585	pseudouridine synthase activity
XppCFBP6546P_RS15015	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XppCFBP6546P_RS15025	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XppCFBP6546P_RS15030	COG0148	phosphopyruvate hydratase activity
XppCFBP6546P_RS15040	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XppCFBP6546P_RS15045	COG0504	CTP synthase activity
XppCFBP6546P_RS15070	COG0306	phosphate transporter
XppCFBP6546P_RS15080	COG1253	flavin adenine dinucleotide binding
XppCFBP6546P_RS15095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XppCFBP6546P_RS15100	COG0477	Major facilitator Superfamily
XppCFBP6546P_RS15110	COG1136	(ABC) transporter
XppCFBP6546P_RS15135	COG2264	protein methyltransferase activity
XppCFBP6546P_RS15165	COG2244	polysaccharide biosynthetic process
XppCFBP6546P_RS15215	COG1595	DNA-templated transcription, initiation
XppCFBP6546P_RS15230	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XppCFBP6546P_RS15240	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XppCFBP6546P_RS15250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XppCFBP6546P_RS15270	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XppCFBP6546P_RS15275	COG0784	Response regulator, receiver
XppCFBP6546P_RS15275	COG4191	Histidine kinase
XppCFBP6546P_RS15295	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS15320	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS15325	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XppCFBP6546P_RS15330	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XppCFBP6546P_RS15345	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XppCFBP6546P_RS15350	COG0077	Prephenate dehydratase
XppCFBP6546P_RS15350	COG1605	Chorismate mutase
XppCFBP6546P_RS15355	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XppCFBP6546P_RS15360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XppCFBP6546P_RS15365	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XppCFBP6546P_RS15405	COG1228	amidohydrolase
XppCFBP6546P_RS15410	COG2986	histidine ammonia-lyase
XppCFBP6546P_RS15420	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XppCFBP6546P_RS15430	COG4993	Dehydrogenase
XppCFBP6546P_RS15440	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XppCFBP6546P_RS15450	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XppCFBP6546P_RS15455	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XppCFBP6546P_RS15460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XppCFBP6546P_RS15470	COG3115	cell septum assembly
XppCFBP6546P_RS15480	COG0359	binds to the 23S rRNA
XppCFBP6546P_RS15485	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XppCFBP6546P_RS15490	COG0360	Binds together with S18 to 16S ribosomal RNA
XppCFBP6546P_RS15495	COG0316	Belongs to the HesB IscA family
XppCFBP6546P_RS15500	COG0017	Asparaginyl-tRNA synthetase
XppCFBP6546P_RS15580	COG0288	reversible hydration of carbon dioxide
XppCFBP6546P_RS15585	COG0662	Cupin 2, conserved barrel domain protein
XppCFBP6546P_RS15595	COG3844	kynureninase activity
XppCFBP6546P_RS15600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XppCFBP6546P_RS15610	COG2925	Exonuclease
XppCFBP6546P_RS15630	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XppCFBP6546P_RS15635	COG0116	Belongs to the methyltransferase superfamily
XppCFBP6546P_RS15635	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XppCFBP6546P_RS15645	COG0488	(ABC) transporter
XppCFBP6546P_RS15680	COG0494	nUDIX hydrolase
XppCFBP6546P_RS15690	COG1024	Enoyl-CoA hydratase
XppCFBP6546P_RS15700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XppCFBP6546P_RS15715	COG4772	TonB-dependent receptor
XppCFBP6546P_RS15725	COG4264	IucA IucC family
XppCFBP6546P_RS15740	COG0019	diaminopimelate decarboxylase activity
XppCFBP6546P_RS15770	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XppCFBP6546P_RS15780	COG1492	cobalamin metabolic process
XppCFBP6546P_RS15790	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XppCFBP6546P_RS15815	COG4206	TonB-dependent receptor
XppCFBP6546P_RS15825	COG0542	response to heat
XppCFBP6546P_RS15870	COG1877	trehalose-phosphatase activity
XppCFBP6546P_RS15875	COG3387	PFAM Glycoside hydrolase 15-related
XppCFBP6546P_RS15895	COG3328	transposase activity
XppCFBP6546P_RS15905	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS15910	COG3011	Protein conserved in bacteria
XppCFBP6546P_RS15925	COG0564	pseudouridine synthase activity
XppCFBP6546P_RS15930	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XppCFBP6546P_RS15940	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XppCFBP6546P_RS15940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XppCFBP6546P_RS15955	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XppCFBP6546P_RS15960	COG0045	succinate-CoA ligase (ADP-forming) activity
XppCFBP6546P_RS16000	COG3328	transposase activity
XppCFBP6546P_RS16010	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XppCFBP6546P_RS16015	COG0237	dephospho-CoA kinase activity
XppCFBP6546P_RS16040	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_RS16050	COG0189	ligase activity
XppCFBP6546P_RS16065	COG3328	transposase activity
XppCFBP6546P_RS16090	COG2003	Belongs to the UPF0758 family
XppCFBP6546P_RS16115	COG3328	transposase activity
XppCFBP6546P_RS16160	COG2022	thiamine diphosphate biosynthetic process
XppCFBP6546P_RS16165	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XppCFBP6546P_RS16170	COG0471	metal ion transport
XppCFBP6546P_RS16170	COG3273	potassium ion transport
XppCFBP6546P_RS16195	COG1970	mechanosensitive ion channel activity
XppCFBP6546P_RS16205	COG1609	Transcriptional regulator
XppCFBP6546P_RS16215	COG3250	beta-galactosidase activity
XppCFBP6546P_RS16220	COG4948	Mandelate Racemase Muconate Lactonizing
XppCFBP6546P_RS16230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XppCFBP6546P_RS16240	COG0308	aminopeptidase N
XppCFBP6546P_RS16245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP6546P_RS16255	COG2895	sulfate adenylyltransferase (ATP) activity
XppCFBP6546P_RS16255	COG0529	Catalyzes the synthesis of activated sulfate
XppCFBP6546P_RS16260	COG0175	sulfate reduction
XppCFBP6546P_RS16265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XppCFBP6546P_RS16270	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XppCFBP6546P_RS16275	COG0175	sulfate reduction
XppCFBP6546P_RS16295	COG2205	protein histidine kinase activity
XppCFBP6546P_RS16295	COG2198	Histidine kinase
XppCFBP6546P_RS16295	COG0784	Response regulator, receiver
XppCFBP6546P_RS16310	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XppCFBP6546P_RS16310	COG1648	precorrin-2 dehydrogenase activity
XppCFBP6546P_RS16325	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XppCFBP6546P_RS16330	COG3588	fructose-bisphosphate aldolase
XppCFBP6546P_RS16335	COG0469	pyruvate kinase activity
XppCFBP6546P_RS16345	COG0126	phosphoglycerate kinase activity
XppCFBP6546P_RS16375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XppCFBP6546P_RS16385	COG3047	cAMP biosynthetic process
XppCFBP6546P_RS16400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XppCFBP6546P_RS16400	COG3453	Protein conserved in bacteria
XppCFBP6546P_RS16405	COG0725	ABC transporter, periplasmic molybdate-binding protein
XppCFBP6546P_RS16410	COG4149	molybdate abc transporter
XppCFBP6546P_RS16415	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XppCFBP6546P_RS16435	COG0642	Histidine kinase
XppCFBP6546P_RS16460	COG1022	Amp-dependent synthetase and ligase
XppCFBP6546P_RS16485	COG1376	ErfK ybiS ycfS ynhG family protein
XppCFBP6546P_RS16490	COG0739	heme binding
XppCFBP6546P_RS16495	COG4773	Receptor
XppCFBP6546P_RS16510	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XppCFBP6546P_RS16515	COG1301	dicarboxylic acid transport
XppCFBP6546P_RS16525	COG2304	oxidoreductase activity
XppCFBP6546P_RS16545	COG0714	Associated with various cellular activities
XppCFBP6546P_RS16575	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XppCFBP6546P_RS16595	COG1957	nucleoside hydrolase
XppCFBP6546P_RS16600	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XppCFBP6546P_RS16610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XppCFBP6546P_RS16625	COG1561	YicC-like family, N-terminal region
XppCFBP6546P_RS16630	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XppCFBP6546P_RS16640	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XppCFBP6546P_RS16645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XppCFBP6546P_RS16660	COG0006	proline dipeptidase activity
XppCFBP6546P_RS16670	COG0006	proline dipeptidase activity
XppCFBP6546P_RS16675	COG3079	Belongs to the UPF0149 family
XppCFBP6546P_RS16695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XppCFBP6546P_RS16715	COG2912	Transglutaminase-like superfamily
XppCFBP6546P_RS16720	COG1773	rubredoxin
XppCFBP6546P_RS16725	COG0352	thiamine-phosphate diphosphorylase activity
XppCFBP6546P_RS16745	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XppCFBP6546P_RS16755	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
XppCFBP6546P_RS16760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XppCFBP6546P_RS16790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XppCFBP6546P_RS16795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XppCFBP6546P_RS16800	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS16810	COG0671	phosphoesterase, PA-phosphatase related
XppCFBP6546P_RS16815	COG3781	membrane
XppCFBP6546P_RS16825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XppCFBP6546P_RS16830	COG0563	adenylate kinase activity
XppCFBP6546P_RS16845	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XppCFBP6546P_RS16855	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XppCFBP6546P_RS16875	COG3710	Transcriptional regulator
XppCFBP6546P_RS16880	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XppCFBP6546P_RS16890	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_RS16895	COG0405	Gamma-glutamyltransferase
XppCFBP6546P_RS16900	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XppCFBP6546P_RS16920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XppCFBP6546P_RS16925	COG0473	3-isopropylmalate dehydrogenase activity
XppCFBP6546P_RS16930	COG0066	3-isopropylmalate dehydratase activity
XppCFBP6546P_RS16935	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XppCFBP6546P_RS16955	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XppCFBP6546P_RS16960	COG1538	Outer membrane efflux protein
XppCFBP6546P_RS16965	COG1519	Transferase
XppCFBP6546P_RS16970	COG1560	Kdo2-lipid A biosynthetic process
XppCFBP6546P_RS16995	COG0281	malic enzyme
XppCFBP6546P_RS16995	COG0280	phosphate acetyltransferase
XppCFBP6546P_RS17000	COG1301	dicarboxylic acid transport
XppCFBP6546P_RS17025	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS17030	COG0667	Aldo Keto reductase
XppCFBP6546P_RS17045	COG2197	response regulator
XppCFBP6546P_RS17055	COG0642	Histidine kinase
XppCFBP6546P_RS17070	COG2851	Citrate transporter
XppCFBP6546P_RS17075	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS17080	COG1609	Transcriptional regulator
XppCFBP6546P_RS17085	COG2211	Major facilitator Superfamily
XppCFBP6546P_RS17110	COG1162	GTPase activity
XppCFBP6546P_RS17115	COG0436	Aminotransferase
XppCFBP6546P_RS17130	COG0726	polysaccharide deacetylase
XppCFBP6546P_RS17135	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XppCFBP6546P_RS17150	COG3964	amidohydrolase
XppCFBP6546P_RS17155	COG0402	S-adenosylhomocysteine deaminase activity
XppCFBP6546P_RS17180	COG3328	transposase activity
XppCFBP6546P_RS17190	COG1307	EDD domain protein, DegV family
XppCFBP6546P_RS17210	COG3791	Glutathione-dependent formaldehyde-activating
XppCFBP6546P_RS17240	COG2205	protein histidine kinase activity
XppCFBP6546P_RS17255	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XppCFBP6546P_RS17270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XppCFBP6546P_RS17280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XppCFBP6546P_RS17285	COG1012	belongs to the aldehyde dehydrogenase family
XppCFBP6546P_RS17290	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XppCFBP6546P_RS17315	COG1183	phosphatidylcholine synthase activity
XppCFBP6546P_RS17325	COG0442	prolyl-tRNA aminoacylation
XppCFBP6546P_RS17340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XppCFBP6546P_RS17345	COG1127	ABC transporter
XppCFBP6546P_RS17350	COG3218	ABC-type transport auxiliary lipoprotein component
XppCFBP6546P_RS17350	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XppCFBP6546P_RS17380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XppCFBP6546P_RS17385	COG0662	Cupin 2, conserved barrel domain protein
XppCFBP6546P_RS17385	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XppCFBP6546P_RS17415	COG2086	electron transfer activity
XppCFBP6546P_RS17430	COG0546	phosphoglycolate phosphatase activity
XppCFBP6546P_RS17430	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XppCFBP6546P_RS17435	COG0277	FAD linked oxidase domain protein
XppCFBP6546P_RS17445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XppCFBP6546P_RS17470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XppCFBP6546P_RS17475	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XppCFBP6546P_RS17480	COG0438	transferase activity, transferring glycosyl groups
XppCFBP6546P_RS17500	COG0438	transferase activity, transferring glycosyl groups
XppCFBP6546P_RS17505	COG0626	cystathionine gamma-synthase activity
XppCFBP6546P_RS17535	COG0625	glutathione transferase activity
XppCFBP6546P_RS17545	COG0513	Belongs to the DEAD box helicase family
XppCFBP6546P_RS17550	COG0720	synthase
XppCFBP6546P_RS17560	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XppCFBP6546P_RS17570	COG1956	GAF domain-containing protein
XppCFBP6546P_RS17585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XppCFBP6546P_RS17590	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XppCFBP6546P_RS17600	COG4991	sh3 domain protein
XppCFBP6546P_RS17610	COG0339	signal peptide processing
XppCFBP6546P_RS17625	COG2132	Multicopper oxidase
XppCFBP6546P_RS17660	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XppCFBP6546P_RS17665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6546P_RS17670	COG1136	(ABC) transporter
XppCFBP6546P_RS17675	COG0577	efflux transmembrane transporter activity
XppCFBP6546P_RS17675	COG1136	(ABC) transporter
XppCFBP6546P_RS17695	COG4191	Histidine kinase
XppCFBP6546P_RS17700	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XppCFBP6546P_RS17725	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XppCFBP6546P_RS17730	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XppCFBP6546P_RS17735	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XppCFBP6546P_RS17740	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XppCFBP6546P_RS17745	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XppCFBP6546P_RS17760	COG0356	it plays a direct role in the translocation of protons across the membrane
XppCFBP6546P_RS17780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XppCFBP6546P_RS17790	COG0508	dehydrogenase complex catalyzes the overall conversion of
XppCFBP6546P_RS17825	COG2011	ABC-type metal ion transport system permease component
XppCFBP6546P_RS17830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XppCFBP6546P_RS17835	COG0697	spore germination
XppCFBP6546P_RS17840	COG1666	GTP binding
XppCFBP6546P_RS17850	COG5002	protein histidine kinase activity
XppCFBP6546P_RS17850	COG2198	Histidine kinase
XppCFBP6546P_RS17850	COG0784	Response regulator, receiver
XppCFBP6546P_RS17875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XppCFBP6546P_RS17880	COG1187	pseudouridine synthase activity
XppCFBP6546P_RS17885	COG2813	Specifically methylates the guanine in position
XppCFBP6546P_RS17900	COG3039	Transposase
XppCFBP6546P_RS17905	COG3328	transposase activity
XppCFBP6546P_RS17920	COG2205	protein histidine kinase activity
XppCFBP6546P_RS17920	COG2202	Pas domain
XppCFBP6546P_RS17940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XppCFBP6546P_RS17945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP6546P_RS18000	COG0842	Transport permease protein
XppCFBP6546P_RS18005	COG1131	(ABC) transporter
XppCFBP6546P_RS18010	COG0025	NhaP-type Na H and K H
XppCFBP6546P_RS18015	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XppCFBP6546P_RS18020	COG1573	uracil-dna glycosylase
XppCFBP6546P_RS18030	COG3384	dioxygenase
XppCFBP6546P_RS18040	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS18050	COG0667	Aldo Keto reductase
XppCFBP6546P_RS18060	COG3590	peptidase
XppCFBP6546P_RS18075	COG0531	amino acid
XppCFBP6546P_RS18090	COG2972	Histidine kinase
XppCFBP6546P_RS18105	COG3685	Protein conserved in bacteria
XppCFBP6546P_RS18110	COG3546	catalase activity
XppCFBP6546P_RS18160	COG1271	oxidase subunit
XppCFBP6546P_RS18165	COG1294	oxidase, subunit
XppCFBP6546P_RS18180	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS18200	COG1063	alcohol dehydrogenase
XppCFBP6546P_RS18210	COG3328	transposase activity
XppCFBP6546P_RS18280	COG0251	oxidation-reduction process
XppCFBP6546P_RS18310	COG0659	secondary active sulfate transmembrane transporter activity
XppCFBP6546P_RS18315	COG0038	chloride channel
XppCFBP6546P_RS18325	COG0024	Methionine aminopeptidase
XppCFBP6546P_RS18360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XppCFBP6546P_RS18365	COG1490	D-aminoacyl-tRNA deacylase activity
XppCFBP6546P_RS18370	COG1560	Kdo2-lipid A biosynthetic process
XppCFBP6546P_RS18415	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XppCFBP6546P_RS18415	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XppCFBP6546P_RS18420	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XppCFBP6546P_RS18425	COG0242	peptide deformylase activity
XppCFBP6546P_RS18430	COG1652	LysM domain
XppCFBP6546P_RS18435	COG0758	DNA mediated transformation
XppCFBP6546P_RS18455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XppCFBP6546P_RS18455	COG1754	DNA topoisomerase type I activity
XppCFBP6546P_RS18460	COG0009	L-threonylcarbamoyladenylate synthase
XppCFBP6546P_RS18475	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS18485	COG0616	signal peptide processing
XppCFBP6546P_RS18490	COG0534	Mate efflux family protein
XppCFBP6546P_RS18510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XppCFBP6546P_RS18515	COG0625	glutathione transferase activity
XppCFBP6546P_RS18535	COG2860	membrane
XppCFBP6546P_RS18540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XppCFBP6546P_RS18545	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XppCFBP6546P_RS18550	COG2201	protein-glutamate methylesterase activity
XppCFBP6546P_RS18555	COG2177	Part of the ABC transporter FtsEX involved in
XppCFBP6546P_RS18560	COG2884	Cell division ATP-binding protein ftsE
XppCFBP6546P_RS18565	COG0513	Belongs to the DEAD box helicase family
XppCFBP6546P_RS18570	COG3118	belongs to the thioredoxin family
XppCFBP6546P_RS18575	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XppCFBP6546P_RS18585	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XppCFBP6546P_RS18610	COG1652	LysM domain
XppCFBP6546P_RS18615	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XppCFBP6546P_RS18615	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XppCFBP6546P_RS18620	COG1473	amidohydrolase
XppCFBP6546P_RS18625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6546P_RS18630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP6546P_RS18650	COG5383	Protein conserved in bacteria
XppCFBP6546P_RS18690	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XppCFBP6546P_RS18695	COG3023	N-Acetylmuramoyl-L-alanine amidase
XppCFBP6546P_RS18715	COG0531	amino acid
XppCFBP6546P_RS18735	COG3328	transposase activity
XppCFBP6546P_RS18745	COG2133	pyrroloquinoline quinone binding
XppCFBP6546P_RS18755	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XppCFBP6546P_RS18760	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XppCFBP6546P_RS18775	COG1610	YqeY-like protein
XppCFBP6546P_RS18780	COG1295	ribonuclease BN
XppCFBP6546P_RS18785	COG0358	DNA primase activity
XppCFBP6546P_RS18800	COG0109	protoheme IX farnesyltransferase activity
XppCFBP6546P_RS18830	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XppCFBP6546P_RS18845	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XppCFBP6546P_RS18885	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XppCFBP6546P_RS18890	COG0739	heme binding
XppCFBP6546P_RS18895	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XppCFBP6546P_RS18905	COG2223	nitrite transmembrane transporter activity
XppCFBP6546P_RS18910	COG0708	Exodeoxyribonuclease III
XppCFBP6546P_RS18915	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XppCFBP6546P_RS18925	COG1192	Involved in chromosome partitioning
XppCFBP6546P_RS18930	COG1475	DNA binding
XppCFBP6546P_RS18945	COG0463	Glycosyl transferase, family 2
XppCFBP6546P_RS18965	COG0756	dUTP diphosphatase activity
XppCFBP6546P_RS18970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XppCFBP6546P_RS18975	COG2003	Belongs to the UPF0758 family
XppCFBP6546P_RS18980	COG0018	arginyl-trna synthetase
XppCFBP6546P_RS18995	COG4221	oxidoreductase activity
XppCFBP6546P_RS19000	COG2755	lipolytic protein G-D-S-L family
XppCFBP6546P_RS19000	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XppCFBP6546P_RS19010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XppCFBP6546P_RS19015	COG1166	arginine decarboxylase activity
XppCFBP6546P_RS19020	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XppCFBP6546P_RS19040	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XppCFBP6546P_RS19040	COG3291	Pkd domain containing protein
XppCFBP6546P_RS19055	COG0606	chelatase, subunit chli
XppCFBP6546P_RS19070	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XppCFBP6546P_RS19095	COG1690	Belongs to the RtcB family
XppCFBP6546P_RS19135	COG1090	epimerase
XppCFBP6546P_RS19145	COG0642	Histidine kinase
XppCFBP6546P_RS19165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XppCFBP6546P_RS19190	COG1011	Hydrolase
XppCFBP6546P_RS19195	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XppCFBP6546P_RS19210	COG0753	catalase activity
XppCFBP6546P_RS19225	COG2197	response regulator
XppCFBP6546P_RS19230	COG4585	Histidine kinase
XppCFBP6546P_RS19235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6546P_RS19240	COG1136	(ABC) transporter
XppCFBP6546P_RS19265	COG0697	spore germination
XppCFBP6546P_RS19290	COG3328	transposase activity
XppCFBP6546P_RS19295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XppCFBP6546P_RS19300	COG0180	Tryptophanyl-tRNA synthetase
XppCFBP6546P_RS19305	COG3237	CsbD-like
XppCFBP6546P_RS19345	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XppCFBP6546P_RS19360	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XppCFBP6546P_RS19365	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XppCFBP6546P_RS19365	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XppCFBP6546P_RS19375	COG3228	Belongs to the MtfA family
XppCFBP6546P_RS19405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XppCFBP6546P_RS19445	COG3328	transposase activity
XppCFBP6546P_RS19460	COG1199	ATP-dependent helicase activity
XppCFBP6546P_RS19475	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XppCFBP6546P_RS19565	COG4555	ABC transporter
XppCFBP6546P_RS19575	COG1476	TRANSCRIPTIONal
XppCFBP6546P_RS19595	COG1230	cation diffusion facilitator family transporter
XppCFBP6546P_RS19600	COG0633	Ferredoxin
XppCFBP6546P_RS19600	COG0543	2 iron, 2 sulfur cluster binding
XppCFBP6546P_RS19605	COG1131	(ABC) transporter
XppCFBP6546P_RS19610	COG0842	Transport permease protein
XppCFBP6546P_RS19615	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XppCFBP6546P_RS19640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XppCFBP6546P_RS19660	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XppCFBP6546P_RS19665	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XppCFBP6546P_RS19675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XppCFBP6546P_RS19675	COG1042	CoA-binding domain protein
XppCFBP6546P_RS19675	COG0045	succinate-CoA ligase (ADP-forming) activity
XppCFBP6546P_RS19680	COG2239	Acts as a magnesium transporter
XppCFBP6546P_RS19700	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XppCFBP6546P_RS19705	COG3387	PFAM Glycoside hydrolase 15-related
XppCFBP6546P_RS19720	COG3100	YcgL domain-containing protein
XppCFBP6546P_RS19725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XppCFBP6546P_RS19735	COG0463	Glycosyl transferase, family 2
XppCFBP6546P_RS19745	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS19785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XppCFBP6546P_RS19800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XppCFBP6546P_RS19835	COG0408	coproporphyrinogen oxidase activity
XppCFBP6546P_RS19870	COG0515	serine threonine protein kinase
XppCFBP6546P_RS19875	COG0631	protein serine/threonine phosphatase activity
XppCFBP6546P_RS19900	COG0667	Aldo Keto reductase
XppCFBP6546P_RS19905	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS19975	COG0154	amidase activity
XppCFBP6546P_RS20000	COG3328	transposase activity
XppCFBP6546P_RS20080	COG0210	DNA helicase
XppCFBP6546P_RS20095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XppCFBP6546P_RS20100	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS20105	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XppCFBP6546P_RS20115	COG2159	amidohydrolase
XppCFBP6546P_RS20140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6546P_RS20160	COG0357	Ribosomal RNA small subunit methyltransferase G
XppCFBP6546P_RS20165	COG3540	Alkaline phosphatase
XppCFBP6546P_RS20175	COG2091	lysine biosynthetic process via aminoadipic acid
XppCFBP6546P_RS20190	COG0708	Exodeoxyribonuclease III
XppCFBP6546P_RS20195	COG1940	carbohydrate kinase activity
XppCFBP6546P_RS20195	COG1846	Transcriptional regulator
XppCFBP6546P_RS20220	COG3162	membrane
XppCFBP6546P_RS20230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XppCFBP6546P_RS20265	COG3507	Belongs to the glycosyl hydrolase 43 family
XppCFBP6546P_RS20285	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS20290	COG0179	Fumarylacetoacetate (FAA) hydrolase
XppCFBP6546P_RS20295	COG4948	Mandelate Racemase Muconate Lactonizing
XppCFBP6546P_RS20300	COG3254	rhamnose metabolic process
XppCFBP6546P_RS20305	COG0738	Major facilitator superfamily
XppCFBP6546P_RS20310	COG1414	Transcriptional regulator
XppCFBP6546P_RS20315	COG2207	Transcriptional regulator
XppCFBP6546P_RS20315	COG1917	Cupin 2, conserved barrel domain protein
XppCFBP6546P_RS20325	COG1971	Probably functions as a manganese efflux pump
XppCFBP6546P_RS20330	COG2205	protein histidine kinase activity
XppCFBP6546P_RS20340	COG3459	Glycosyltransferase 36 associated
XppCFBP6546P_RS20345	COG2211	Major facilitator Superfamily
XppCFBP6546P_RS20350	COG3265	gluconokinase activity
XppCFBP6546P_RS20355	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XppCFBP6546P_RS20375	COG3328	transposase activity
XppCFBP6546P_RS20380	COG2911	Protein conserved in bacteria
XppCFBP6546P_RS20385	COG0729	surface antigen
XppCFBP6546P_RS20390	COG4771	TonB-dependent receptor
XppCFBP6546P_RS20395	COG0457	Tetratricopeptide repeat
XppCFBP6546P_RS20405	COG0752	glycyl-tRNA synthetase alpha subunit
XppCFBP6546P_RS20410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XppCFBP6546P_RS20420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XppCFBP6546P_RS20420	COG0519	Catalyzes the synthesis of GMP from XMP
XppCFBP6546P_RS20435	COG0805	protein transport
XppCFBP6546P_RS20440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XppCFBP6546P_RS20445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XppCFBP6546P_RS20455	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XppCFBP6546P_RS20475	COG2974	May be involved in recombination
XppCFBP6546P_RS20480	COG0037	tRNA processing
XppCFBP6546P_RS20485	COG2115	Belongs to the xylose isomerase family
XppCFBP6546P_RS20495	COG3661	Belongs to the glycosyl hydrolase 67 family
XppCFBP6546P_RS20505	COG4948	Mandelate Racemase Muconate Lactonizing
XppCFBP6546P_RS20515	COG1472	Belongs to the glycosyl hydrolase 3 family
XppCFBP6546P_RS20520	COG0246	Mannitol dehydrogenase
XppCFBP6546P_RS20575	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XppCFBP6546P_RS20600	COG3386	PFAM SMP-30 Gluconolaconase
XppCFBP6546P_RS20610	COG3250	beta-galactosidase activity
XppCFBP6546P_RS20615	COG1904	glucuronate isomerase
XppCFBP6546P_RS20620	COG3693	PFAM glycoside hydrolase, family 10
XppCFBP6546P_RS20625	COG3693	PFAM glycoside hydrolase, family 10
XppCFBP6546P_RS20640	COG2211	Major facilitator Superfamily
XppCFBP6546P_RS20680	COG3039	Transposase
XppCFBP6546P_RS20705	COG3328	transposase activity
XppCFBP6546P_RS20750	COG2937	Belongs to the GPAT DAPAT family
XppCFBP6546P_RS20780	COG0284	orotidine-5'-phosphate decarboxylase activity
XppCFBP6546P_RS20785	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XppCFBP6546P_RS20800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XppCFBP6546P_RS20850	COG0210	DNA helicase
XppCFBP6546P_RS20855	COG1435	thymidine kinase activity
XppCFBP6546P_RS20865	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XppCFBP6546P_RS20875	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XppCFBP6546P_RS20905	COG3135	benzoate transporter
XppCFBP6546P_RS20935	COG0676	glucose-6-phosphate 1-epimerase activity
XppCFBP6546P_RS20945	COG3012	SEC-C Motif Domain Protein
XppCFBP6546P_RS20985	COG3328	transposase activity
XppCFBP6546P_RS21000	COG0730	response to heat
XppCFBP6546P_RS21010	COG3328	transposase activity
XppCFBP6546P_RS21030	COG0302	gtp cyclohydrolase
XppCFBP6546P_RS21045	COG1566	PFAM secretion protein HlyD family protein
XppCFBP6546P_RS21055	COG1289	transmembrane transporter activity
XppCFBP6546P_RS21060	COG0477	Major facilitator Superfamily
XppCFBP6546P_RS21070	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS21075	COG4221	oxidoreductase activity
XppCFBP6546P_RS21085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XppCFBP6546P_RS21110	COG3328	transposase activity
XppCFBP6546P_RS21135	COG0564	pseudouridine synthase activity
XppCFBP6546P_RS21170	COG3012	SEC-C Motif Domain Protein
XppCFBP6546P_RS21240	COG4790	Type iii secretion
XppCFBP6546P_RS21405	COG3039	Transposase
XppCFBP6546P_RS21500	COG0439	Biotin carboxylase
XppCFBP6546P_RS21525	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_RS21580	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XppCFBP6546P_RS21585	COG1074	ATP-dependent DNA helicase activity
XppCFBP6546P_RS21590	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XppCFBP6546P_RS21625	COG1127	ABC transporter
XppCFBP6546P_RS21630	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XppCFBP6546P_RS21635	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XppCFBP6546P_RS21650	COG2853	Lipoprotein
XppCFBP6546P_RS21665	COG0386	Belongs to the glutathione peroxidase family
XppCFBP6546P_RS21675	COG1322	Protein conserved in bacteria
XppCFBP6546P_RS21685	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_RS21705	COG0531	amino acid
XppCFBP6546P_RS21710	COG3537	Alpha-1,2-mannosidase
XppCFBP6546P_RS21725	COG2199	diguanylate cyclase activity
XppCFBP6546P_RS21725	COG2203	Gaf domain
XppCFBP6546P_RS21730	COG3835	regulator
XppCFBP6546P_RS21735	COG1929	Belongs to the glycerate kinase type-1 family
XppCFBP6546P_RS21740	COG2271	Major facilitator Superfamily
XppCFBP6546P_RS21755	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XppCFBP6546P_RS21760	COG0861	Integral membrane protein TerC family
XppCFBP6546P_RS21770	COG0584	glycerophosphoryl diester phosphodiesterase
XppCFBP6546P_RS21785	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XppCFBP6546P_RS21790	COG0726	polysaccharide deacetylase
XppCFBP6546P_RS21800	COG0706	membrane insertase activity
XppCFBP6546P_RS21805	COG0594	ribonuclease P activity
XppCFBP6546P_RS21930	COG3328	transposase activity
XppCFBP6546P_RS21955	COG4962	Type ii secretion system protein e
XppCFBP6546P_RS21970	COG3451	type IV secretory pathway VirB4
XppCFBP6546P_RS21985	COG3846	protein secretion by the type IV secretion system
XppCFBP6546P_RS22050	COG1487	ribonuclease activity
XppCFBP6546P_RS22055	COG4691	Plasmid stability protein
XppCFBP6546P_RS22060	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XppCFBP6546P_RS22100	COG3328	transposase activity
XppCFBP6546P_RS22190	COG3328	transposase activity
XppCFBP6546P_RS22265	COG3328	transposase activity
XppCFBP6546P_RS22305	COG1487	ribonuclease activity
XppCFBP6546P_RS22310	COG4691	Plasmid stability protein
XppCFBP6546P_RS22315	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XppCFBP6546P_RS22430	COG3039	Transposase