locus-tag	class	description
OM951_RS00005	COG2963	transposase activity
OM951_RS00010	COG3104	oligopeptide transport
OM951_RS00030	COG2852	Protein conserved in bacteria
OM951_RS00035	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OM951_RS00055	COG1320	monovalent cation:proton antiporter activity
OM951_RS00060	COG2212	antiporter activity
OM951_RS00070	COG0651	ATP synthesis coupled electron transport
OM951_RS00075	COG1006	Multisubunit Na H antiporter MnhC subunit
OM951_RS00080	COG2111	Na H antiporter
OM951_RS00080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OM951_RS00100	COG3179	chitinase
OM951_RS00120	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OM951_RS00125	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OM951_RS00145	COG1597	lipid kinase activity
OM951_RS00175	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OM951_RS00180	COG0134	indole-3-glycerol-phosphate synthase activity
OM951_RS00190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM951_RS00195	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OM951_RS00205	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
OM951_RS00215	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OM951_RS00230	COG1051	belongs to the nudix hydrolase family
OM951_RS00270	COG0316	Belongs to the HesB IscA family
OM951_RS00285	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OM951_RS00300	COG2814	Major facilitator Superfamily
OM951_RS00310	COG2814	Major facilitator Superfamily
OM951_RS00315	COG1289	transmembrane transporter activity
OM951_RS00325	COG0151	Belongs to the GarS family
OM951_RS00335	COG0138	bifunctional purine biosynthesis protein purh
OM951_RS00340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OM951_RS00345	COG2267	carboxylic ester hydrolase activity
OM951_RS00350	COG2453	phosphatase
OM951_RS00350	COG0671	phosphoesterase, PA-phosphatase related
OM951_RS00375	COG4589	Belongs to the CDS family
OM951_RS00380	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OM951_RS00400	COG2264	protein methyltransferase activity
OM951_RS00415	COG0439	Biotin carboxylase
OM951_RS00425	COG0511	ligase activity, forming carbon-carbon bonds
OM951_RS00430	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OM951_RS00440	COG1324	tolerance protein
OM951_RS00460	COG0459	protein refolding
OM951_RS00475	COG3550	peptidyl-serine autophosphorylation
OM951_RS00480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OM951_RS00505	COG3386	PFAM SMP-30 Gluconolaconase
OM951_RS00515	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OM951_RS00520	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OM951_RS00540	COG3039	Transposase
OM951_RS00560	COG0778	Nitroreductase
OM951_RS00565	COG2353	YceI-like domain
OM951_RS00600	COG3052	prosthetic group binding
OM951_RS00625	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OM951_RS00635	COG1802	Transcriptional regulator
OM951_RS00690	COG3328	transposase activity
OM951_RS00745	COG1959	2 iron, 2 sulfur cluster binding
OM951_RS00770	COG0697	spore germination
OM951_RS00775	COG4305	rare lipoprotein A
OM951_RS00780	COG5297	Belongs to the glycosyl hydrolase family 6
OM951_RS00790	COG1113	amino acid transport
OM951_RS00800	COG0598	Magnesium transport protein CorA
OM951_RS00845	COG5002	protein histidine kinase activity
OM951_RS00845	COG5001	Diguanylate cyclase
OM951_RS00845	COG3447	MASE1 domain protein
OM951_RS00855	COG2205	protein histidine kinase activity
OM951_RS00855	COG0784	Response regulator, receiver
OM951_RS00885	COG2943	transferase activity, transferring hexosyl groups
OM951_RS00895	COG3275	phosphorelay sensor kinase activity
OM951_RS00905	COG0181	hydroxymethylbilane synthase activity
OM951_RS00940	COG1505	serine-type exopeptidase activity
OM951_RS00950	COG0436	Aminotransferase
OM951_RS00960	COG2832	Protein of unknown function (DUF454)
OM951_RS00970	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OM951_RS00980	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OM951_RS00985	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OM951_RS00990	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OM951_RS01015	COG2226	methyltransferase
OM951_RS01020	COG5001	Diguanylate cyclase
OM951_RS01020	COG3300	MHYT domain
OM951_RS01025	COG0308	aminopeptidase N
OM951_RS01070	COG3284	Transcriptional regulator
OM951_RS01085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM951_RS01090	COG1077	Cell shape determining protein MreB Mrl
OM951_RS01095	COG1792	Involved in formation and maintenance of cell shape
OM951_RS01110	COG0772	Belongs to the SEDS family
OM951_RS01150	COG2951	lytic endotransglycosylase activity
OM951_RS01155	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OM951_RS01160	COG1686	Belongs to the peptidase S11 family
OM951_RS01170	COG2921	Belongs to the UPF0250 family
OM951_RS01175	COG0321	lipoyl(octanoyl) transferase activity
OM951_RS01180	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OM951_RS01205	COG1056	cytidyltransferase-related domain
OM951_RS01205	COG1051	belongs to the nudix hydrolase family
OM951_RS01240	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OM951_RS01245	COG0673	inositol 2-dehydrogenase activity
OM951_RS01250	COG2823	Periplasmic or secreted lipoprotein
OM951_RS01255	COG4251	negative regulation of phosphorylation
OM951_RS01260	COG0784	Response regulator, receiver
OM951_RS01265	COG4191	Histidine kinase
OM951_RS01270	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OM951_RS01325	COG1459	type II secretion system
OM951_RS01370	COG2188	Transcriptional regulator
OM951_RS01380	COG1609	Transcriptional regulator
OM951_RS01385	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OM951_RS01390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OM951_RS01400	COG0617	tRNA 3'-terminal CCA addition
OM951_RS01405	COG3039	Transposase
OM951_RS01420	COG0525	valine-tRNA ligase activity
OM951_RS01435	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OM951_RS01445	COG0795	lipopolysaccharide-transporting ATPase activity
OM951_RS01460	COG4974	Belongs to the 'phage' integrase family
OM951_RS01470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OM951_RS01475	COG0047	phosphoribosylformylglycinamidine synthase activity
OM951_RS01475	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OM951_RS01480	COG5295	Hep Hag repeat protein
OM951_RS01485	COG1404	Belongs to the peptidase S8 family
OM951_RS01495	COG1404	Belongs to the peptidase S8 family
OM951_RS01500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OM951_RS01505	COG1459	type II secretion system
OM951_RS01510	COG2165	general secretion pathway protein
OM951_RS01515	COG4970	Tfp pilus assembly protein FimT
OM951_RS01520	COG2165	general secretion pathway protein
OM951_RS01525	COG4795	General secretion pathway protein
OM951_RS01530	COG3156	type II secretion system protein K
OM951_RS01535	COG3166	PFAM Fimbrial assembly family protein
OM951_RS01550	COG1450	Type ii and iii secretion system protein
OM951_RS01565	COG2188	Transcriptional regulator
OM951_RS01635	COG1215	transferase activity, transferring glycosyl groups
OM951_RS01640	COG1215	transferase activity, transferring glycosyl groups
OM951_RS01645	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OM951_RS01670	COG0242	peptide deformylase activity
OM951_RS01675	COG0488	(ABC) transporter
OM951_RS01685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OM951_RS01690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OM951_RS01700	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM951_RS01700	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM951_RS01720	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OM951_RS01725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OM951_RS01730	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OM951_RS01745	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OM951_RS01750	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OM951_RS01760	COG2205	protein histidine kinase activity
OM951_RS01765	COG0745	RESPONSE REGULATOR receiver
OM951_RS01780	COG1988	membrane-bound metal-dependent
OM951_RS01785	COG0792	nuclease activity
OM951_RS01825	COG3116	cell division
OM951_RS01835	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OM951_RS01840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OM951_RS01845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM951_RS01855	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OM951_RS01860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OM951_RS01865	COG1181	Belongs to the D-alanine--D-alanine ligase family
OM951_RS01870	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OM951_RS01885	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
OM951_RS01895	COG0739	heme binding
OM951_RS01900	COG0653	protein targeting
OM951_RS01905	COG0494	nUDIX hydrolase
OM951_RS01915	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OM951_RS01925	COG0604	alcohol dehydrogenase
OM951_RS01925	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS01925	COG3321	synthase
OM951_RS01940	COG0366	Alpha amylase catalytic
OM951_RS01975	COG2226	methyltransferase
OM951_RS01980	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OM951_RS01990	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OM951_RS02030	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OM951_RS02040	COG4106	trans-aconitate 2-methyltransferase activity
OM951_RS02045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM951_RS02060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM951_RS02065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OM951_RS02070	COG0667	Aldo Keto reductase
OM951_RS02080	COG4771	TonB-dependent receptor
OM951_RS02100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OM951_RS02105	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OM951_RS02115	COG2175	clavaminate synthase activity
OM951_RS02125	COG4181	ATPase activity
OM951_RS02140	COG0642	Histidine kinase
OM951_RS02150	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OM951_RS02160	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OM951_RS02170	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OM951_RS02175	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OM951_RS02190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OM951_RS02195	COG2967	ApaG domain
OM951_RS02200	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OM951_RS02205	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OM951_RS02210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM951_RS02215	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OM951_RS02225	COG0123	including yeast histone deacetylase and acetoin utilization protein
OM951_RS02230	COG2096	Adenosyltransferase
OM951_RS02240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM951_RS02245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM951_RS02275	COG3384	dioxygenase
OM951_RS02280	COG0583	DNA-binding transcription factor activity
OM951_RS02285	COG0318	PFAM AMP-dependent synthetase and ligase
OM951_RS02295	COG1024	Enoyl-CoA hydratase
OM951_RS02315	COG3386	PFAM SMP-30 Gluconolaconase
OM951_RS02325	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
OM951_RS02350	COG0697	spore germination
OM951_RS02360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM951_RS02380	COG2205	protein histidine kinase activity
OM951_RS02385	COG2197	response regulator
OM951_RS02395	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OM951_RS02410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OM951_RS02415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM951_RS02420	COG0583	DNA-binding transcription factor activity
OM951_RS02425	COG3634	alkyl hydroperoxide reductase activity
OM951_RS02435	COG2890	protein-(glutamine-N5) methyltransferase activity
OM951_RS02455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM951_RS02455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM951_RS02510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM951_RS02515	COG1404	Belongs to the peptidase S8 family
OM951_RS02520	COG1404	Belongs to the peptidase S8 family
OM951_RS02525	COG1404	Belongs to the peptidase S8 family
OM951_RS02530	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OM951_RS02555	COG1295	ribonuclease BN
OM951_RS02560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM951_RS02565	COG1254	Belongs to the acylphosphatase family
OM951_RS02580	COG0521	Mo-molybdopterin cofactor biosynthetic process
OM951_RS02590	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OM951_RS02595	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OM951_RS02605	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OM951_RS02610	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OM951_RS02620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OM951_RS02625	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OM951_RS02630	COG0193	aminoacyl-tRNA hydrolase activity
OM951_RS02635	COG0012	GTP binding
OM951_RS02655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OM951_RS02670	COG0250	Participates in transcription elongation, termination and antitermination
OM951_RS02675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OM951_RS02680	COG0081	regulation of translation
OM951_RS02685	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OM951_RS02695	COG0085	RNA polymerase activity
OM951_RS02700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OM951_RS02705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OM951_RS02710	COG0049	tRNA binding
OM951_RS02715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OM951_RS02720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OM951_RS02740	COG3328	transposase activity
OM951_RS02745	COG0051	transcription antitermination factor activity, RNA binding
OM951_RS02750	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OM951_RS02755	COG0088	Forms part of the polypeptide exit tunnel
OM951_RS02760	COG0089	rRNA binding
OM951_RS02765	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OM951_RS02770	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OM951_RS02780	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OM951_RS02785	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OM951_RS02790	COG0255	Belongs to the universal ribosomal protein uL29 family
OM951_RS02795	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OM951_RS02805	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OM951_RS02810	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OM951_RS02820	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OM951_RS02825	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OM951_RS02830	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OM951_RS02840	COG1841	ribosomal large subunit assembly
OM951_RS02845	COG0200	Binds to the 23S rRNA
OM951_RS02850	COG0201	protein transport
OM951_RS02875	COG0203	ribosomal protein L17
OM951_RS02880	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OM951_RS02900	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
OM951_RS02910	COG0154	amidase activity
OM951_RS02920	COG1217	gtp-binding protein TYPA
OM951_RS02925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OM951_RS02930	COG0039	L-malate dehydrogenase activity
OM951_RS02935	COG0625	glutathione transferase activity
OM951_RS02950	COG0446	pyridine nucleotide-disulphide oxidoreductase
OM951_RS02950	COG1902	pentaerythritol trinitrate reductase activity
OM951_RS02955	COG0604	alcohol dehydrogenase
OM951_RS02965	COG3328	transposase activity
OM951_RS02975	COG2885	chlorophyll binding
OM951_RS02995	COG0156	8-amino-7-oxononanoate synthase activity
OM951_RS03000	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OM951_RS03005	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OM951_RS03010	COG4208	sulfate ABC transporter
OM951_RS03015	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OM951_RS03050	COG0406	alpha-ribazole phosphatase activity
OM951_RS03060	COG0285	dihydrofolate synthase activity
OM951_RS03080	COG2833	Protein of unknown function (DUF455)
OM951_RS03090	COG3291	Pkd domain containing protein
OM951_RS03100	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM951_RS03105	COG0671	phosphoesterase, PA-phosphatase related
OM951_RS03110	COG0438	transferase activity, transferring glycosyl groups
OM951_RS03120	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OM951_RS03135	COG4783	chaperone-mediated protein folding
OM951_RS03150	COG0473	3-isopropylmalate dehydrogenase activity
OM951_RS03190	COG3328	transposase activity
OM951_RS03205	COG0544	peptidyl-prolyl cis-trans isomerase activity
OM951_RS03215	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OM951_RS03245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM951_RS03255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM951_RS03265	COG0328	RNA-DNA hybrid ribonuclease activity
OM951_RS03270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OM951_RS03275	COG0631	protein serine/threonine phosphatase activity
OM951_RS03300	COG0859	PFAM glycosyl transferase family 9
OM951_RS03305	COG3642	lipopolysaccharide core region biosynthetic process
OM951_RS03310	COG1234	tRNA 3'-trailer cleavage
OM951_RS03315	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OM951_RS03325	COG0315	cyclic pyranopterin monophosphate synthase activity
OM951_RS03330	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OM951_RS03335	COG0314	molybdopterin synthase activity
OM951_RS03355	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OM951_RS03360	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OM951_RS03365	COG0537	adenosine 5'-monophosphoramidase activity
OM951_RS03385	COG0714	Associated with various cellular activities
OM951_RS03395	COG0424	maF-like protein
OM951_RS03400	COG1399	metal-binding, possibly nucleic acid-binding protein
OM951_RS03405	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OM951_RS03410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM951_RS03425	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS03440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OM951_RS03445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OM951_RS03475	COG3829	transcription factor binding
OM951_RS03495	COG3328	transposase activity
OM951_RS03525	COG2373	Large extracellular alpha-helical protein
OM951_RS03545	COG3852	Histidine kinase
OM951_RS03550	COG4953	penicillin-binding protein 1C
OM951_RS03560	COG0678	peroxiredoxin activity
OM951_RS03580	COG0330	HflC and HflK could
OM951_RS03585	COG0330	HflC and HflK could
OM951_RS03595	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OM951_RS03600	COG0308	aminopeptidase N
OM951_RS03610	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS03615	COG1309	transcriptional regulator
OM951_RS03640	COG3328	transposase activity
OM951_RS03690	COG3387	PFAM Glycoside hydrolase 15-related
OM951_RS03695	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS03700	COG3537	Alpha-1,2-mannosidase
OM951_RS03725	COG0492	ferredoxin-NADP+ reductase activity
OM951_RS03755	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OM951_RS03760	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OM951_RS03765	COG2080	2 iron, 2 sulfur cluster binding
OM951_RS03800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OM951_RS03815	COG0587	DNA-directed DNA polymerase activity
OM951_RS03835	COG1297	OPT oligopeptide transporter protein
OM951_RS03860	COG1506	peptidase
OM951_RS03860	COG0823	Involved in the tonB-independent uptake of proteins
OM951_RS03890	COG2207	Transcriptional regulator
OM951_RS03890	COG1917	Cupin 2, conserved barrel domain protein
OM951_RS03905	COG0753	catalase activity
OM951_RS03910	COG0656	L-ascorbic acid biosynthetic process
OM951_RS03920	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OM951_RS03920	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OM951_RS03970	COG2194	sulfuric ester hydrolase activity
OM951_RS03985	COG0745	RESPONSE REGULATOR receiver
OM951_RS03990	COG0642	Histidine kinase
OM951_RS04000	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
OM951_RS04005	COG2894	cell division
OM951_RS04010	COG0850	regulation of cytokinetic process
OM951_RS04020	COG4585	Histidine kinase
OM951_RS04025	COG2197	response regulator
OM951_RS04040	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OM951_RS04065	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OM951_RS04075	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
OM951_RS04090	COG1595	DNA-templated transcription, initiation
OM951_RS04100	COG1946	Acyl-CoA thioesterase
OM951_RS04115	COG0824	Thioesterase
OM951_RS04120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OM951_RS04125	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OM951_RS04130	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OM951_RS04135	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OM951_RS04140	COG0268	Binds directly to 16S ribosomal RNA
OM951_RS04150	COG0196	riboflavin kinase activity
OM951_RS04155	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OM951_RS04160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OM951_RS04165	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OM951_RS04180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OM951_RS04185	COG1845	cytochrome c oxidase, subunit III
OM951_RS04190	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OM951_RS04205	COG3152	Membrane
OM951_RS04215	COG2207	Transcriptional regulator
OM951_RS04240	COG1366	Belongs to the anti-sigma-factor antagonist family
OM951_RS04245	COG1366	Belongs to the anti-sigma-factor antagonist family
OM951_RS04250	COG2172	sigma factor antagonist activity
OM951_RS04275	COG4771	TonB-dependent receptor
OM951_RS04285	COG5507	3-demethylubiquinone-9 3-methyltransferase
OM951_RS04290	COG2205	protein histidine kinase activity
OM951_RS04300	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OM951_RS04310	COG4191	Histidine kinase
OM951_RS04310	COG0784	Response regulator, receiver
OM951_RS04335	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OM951_RS04345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM951_RS04350	COG0228	four-way junction DNA binding
OM951_RS04355	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OM951_RS04360	COG0336	Belongs to the RNA methyltransferase TrmD family
OM951_RS04365	COG0335	large ribosomal subunit rRNA binding
OM951_RS04370	COG0534	Mate efflux family protein
OM951_RS04395	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OM951_RS04405	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OM951_RS04410	COG2801	Transposase and inactivated derivatives
OM951_RS04445	COG1960	acyl-CoA dehydrogenase activity
OM951_RS04455	COG1309	transcriptional regulator
OM951_RS04460	COG4771	TonB-dependent receptor
OM951_RS04470	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OM951_RS04475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM951_RS04480	COG0463	Glycosyl transferase, family 2
OM951_RS04485	COG0516	GMP reductase activity
OM951_RS04485	COG0517	IMP dehydrogenase activity
OM951_RS04490	COG2982	Protein involved in outer membrane biogenesis
OM951_RS04495	COG1272	protein, Hemolysin III
OM951_RS04500	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OM951_RS04505	COG0739	heme binding
OM951_RS04510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM951_RS04515	COG0626	cystathionine gamma-synthase activity
OM951_RS04520	COG0460	homoserine dehydrogenase
OM951_RS04520	COG0527	aspartate kinase activity
OM951_RS04530	COG1760	l-serine dehydratase
OM951_RS04550	COG2353	YceI-like domain
OM951_RS04580	COG2814	Major facilitator Superfamily
OM951_RS04585	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OM951_RS04595	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OM951_RS04600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OM951_RS04605	COG0259	pyridoxamine-phosphate oxidase activity
OM951_RS04615	COG1842	Phage shock protein A
OM951_RS04640	COG0754	glutathionylspermidine amidase activity
OM951_RS04645	COG2814	Major facilitator Superfamily
OM951_RS04705	COG0531	amino acid
OM951_RS04710	COG2197	response regulator
OM951_RS04740	COG3328	transposase activity
OM951_RS04745	COG3328	transposase activity
OM951_RS04750	COG2801	Transposase and inactivated derivatives
OM951_RS04765	COG1113	amino acid transport
OM951_RS04775	COG1271	oxidase subunit
OM951_RS04845	COG2951	lytic endotransglycosylase activity
OM951_RS04860	COG0551	DNA topoisomerase type I activity
OM951_RS04860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM951_RS04910	COG1294	oxidase, subunit
OM951_RS04920	COG2239	Acts as a magnesium transporter
OM951_RS04930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OM951_RS04935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM951_RS04945	COG1660	Displays ATPase and GTPase activities
OM951_RS04950	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OM951_RS04955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM951_RS04970	COG1137	ATPase activity
OM951_RS04975	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OM951_RS04985	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OM951_RS04995	COG0271	Belongs to the BolA IbaG family
OM951_RS05000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OM951_RS05020	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OM951_RS05035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OM951_RS05045	COG0628	permease
OM951_RS05055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OM951_RS05070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM951_RS05075	COG1555	photosystem II stabilization
OM951_RS05080	COG3328	transposase activity
OM951_RS05090	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OM951_RS05095	COG1477	protein flavinylation
OM951_RS05120	COG3128	pkhd-type hydroxylase
OM951_RS05125	COG4774	siderophore transport
OM951_RS05130	COG2146	nitrite reductase [NAD(P)H] activity
OM951_RS05135	COG0456	acetyltransferase
OM951_RS05140	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OM951_RS05145	COG0719	Fe-S assembly protein
OM951_RS05155	COG0719	Fe-S assembly protein
OM951_RS05160	COG1959	2 iron, 2 sulfur cluster binding
OM951_RS05170	COG0693	protein deglycase activity
OM951_RS05190	COG0739	heme binding
OM951_RS05205	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OM951_RS05230	COG0519	Catalyzes the synthesis of GMP from XMP
OM951_RS05235	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OM951_RS05240	COG1678	Uncharacterized ACR, COG1678
OM951_RS05245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OM951_RS05250	COG0540	Belongs to the ATCase OTCase family
OM951_RS05255	COG1764	response to oxidative stress
OM951_RS05265	COG0384	phenazine biosynthesis protein PhzF
OM951_RS05270	COG0384	phenazine biosynthesis protein PhzF
OM951_RS05275	COG0527	aspartate kinase activity
OM951_RS05290	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OM951_RS05300	COG0142	geranyltranstransferase activity
OM951_RS05305	COG0629	single-stranded DNA binding
OM951_RS05310	COG3706	GGDEF domain
OM951_RS05310	COG5001	Diguanylate cyclase
OM951_RS05310	COG2203	Gaf domain
OM951_RS05310	COG4251	negative regulation of phosphorylation
OM951_RS05320	COG2080	2 iron, 2 sulfur cluster binding
OM951_RS05325	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OM951_RS05330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OM951_RS05335	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OM951_RS05375	COG2879	small protein
OM951_RS05380	COG1966	Carbon starvation protein
OM951_RS05385	COG1741	Belongs to the pirin family
OM951_RS05400	COG1741	Belongs to the pirin family
OM951_RS05410	COG1515	deoxyribonuclease V activity
OM951_RS05425	COG3590	peptidase
OM951_RS05435	COG2201	protein-glutamate methylesterase activity
OM951_RS05440	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OM951_RS05445	COG2199	diguanylate cyclase activity
OM951_RS05445	COG2202	Pas domain
OM951_RS05445	COG2200	EAL domain
OM951_RS05450	COG0835	chemotaxis
OM951_RS05455	COG0840	transmembrane signaling receptor activity
OM951_RS05460	COG0643	Histidine kinase
OM951_RS05460	COG2198	Histidine kinase
OM951_RS05470	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OM951_RS05485	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OM951_RS05490	COG0745	RESPONSE REGULATOR receiver
OM951_RS05495	COG2205	protein histidine kinase activity
OM951_RS05510	COG4452	Inner membrane protein CreD
OM951_RS05535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM951_RS05540	COG0735	belongs to the Fur family
OM951_RS05555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM951_RS05565	COG1309	transcriptional regulator
OM951_RS05575	COG2207	Transcriptional regulator
OM951_RS05585	COG0583	DNA-binding transcription factor activity
OM951_RS05590	COG2814	Major facilitator Superfamily
OM951_RS05595	COG0667	Aldo Keto reductase
OM951_RS05710	COG1595	DNA-templated transcription, initiation
OM951_RS05720	COG5001	Diguanylate cyclase
OM951_RS05720	COG5002	protein histidine kinase activity
OM951_RS05725	COG1187	pseudouridine synthase activity
OM951_RS05745	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OM951_RS05755	COG0475	glutathione-regulated potassium exporter activity
OM951_RS05760	COG5000	phosphorelay sensor kinase activity
OM951_RS05760	COG5002	protein histidine kinase activity
OM951_RS05765	COG0745	RESPONSE REGULATOR receiver
OM951_RS05795	COG1132	(ABC) transporter
OM951_RS05845	COG2155	Conserved Protein
OM951_RS05870	COG3118	belongs to the thioredoxin family
OM951_RS05880	COG0495	leucyl-tRNA aminoacylation
OM951_RS05910	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OM951_RS05925	COG3328	transposase activity
OM951_RS05935	COG2968	Membrane
OM951_RS05940	COG0424	maF-like protein
OM951_RS05950	COG3164	Protein of unknown function
OM951_RS05960	COG0312	modulator of DNA gyrase
OM951_RS05965	COG3028	Belongs to the UPF0307 family
OM951_RS05970	COG0312	modulator of DNA gyrase
OM951_RS05980	COG4104	PAAR repeat-containing protein
OM951_RS05985	COG0142	geranyltranstransferase activity
OM951_RS05990	COG1722	exodeoxyribonuclease VII activity
OM951_RS05995	COG0037	tRNA processing
OM951_RS06000	COG1785	Belongs to the alkaline phosphatase family
OM951_RS06005	COG1301	dicarboxylic acid transport
OM951_RS06010	COG4106	trans-aconitate 2-methyltransferase activity
OM951_RS06020	COG0791	NLP P60 protein
OM951_RS06025	COG0791	NLP P60 protein
OM951_RS06030	COG1047	Peptidyl-prolyl cis-trans
OM951_RS06035	COG2311	Membrane
OM951_RS06040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM951_RS06045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM951_RS06100	COG0489	protein tyrosine kinase activity
OM951_RS06105	COG0717	Belongs to the dCTP deaminase family
OM951_RS06130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM951_RS06135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM951_RS06160	COG0433	COG0433 Predicted ATPase
OM951_RS06170	COG0688	phosphatidylethanolamine metabolic process
OM951_RS06180	COG2890	protein-(glutamine-N5) methyltransferase activity
OM951_RS06185	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OM951_RS06190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OM951_RS06195	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OM951_RS06210	COG0101	tRNA pseudouridine synthase activity
OM951_RS06215	COG0135	phosphoribosylanthranilate isomerase activity
OM951_RS06225	COG0133	tryptophan synthase activity
OM951_RS06235	COG0159	tryptophan synthase activity
OM951_RS06240	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OM951_RS06245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OM951_RS06275	COG4221	oxidoreductase activity
OM951_RS06280	COG0149	triose-phosphate isomerase activity
OM951_RS06295	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM951_RS06300	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM951_RS06305	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM951_RS06310	COG0649	NAD binding
OM951_RS06315	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
OM951_RS06320	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OM951_RS06330	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OM951_RS06335	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM951_RS06360	COG1007	ATP synthesis coupled electron transport
OM951_RS06370	COG0779	Required for maturation of 30S ribosomal subunits
OM951_RS06375	COG0195	Participates in both transcription termination and antitermination
OM951_RS06380	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OM951_RS06385	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OM951_RS06390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OM951_RS06395	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OM951_RS06400	COG1185	polyribonucleotide nucleotidyltransferase activity
OM951_RS06435	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OM951_RS06445	COG2095	MarC family integral membrane protein
OM951_RS06455	COG1611	Belongs to the LOG family
OM951_RS06460	COG3275	phosphorelay sensor kinase activity
OM951_RS06605	COG3179	chitinase
OM951_RS06650	COG4695	Portal protein
OM951_RS06760	COG0556	nucleotide-excision repair
OM951_RS06775	COG3505	Type IV secretory pathway VirD4
OM951_RS06795	COG2948	multi-organism process
OM951_RS06815	COG3702	type iv secretory pathway
OM951_RS06860	COG0326	Molecular chaperone. Has ATPase activity
OM951_RS06865	COG0742	ribosomal rna small subunit methyltransferase
OM951_RS06870	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OM951_RS06880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OM951_RS06885	COG0405	Gamma-glutamyltransferase
OM951_RS06890	COG3291	Pkd domain containing protein
OM951_RS06895	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OM951_RS06930	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OM951_RS06935	COG0343	queuine tRNA-ribosyltransferase activity
OM951_RS06940	COG1862	Preprotein translocase
OM951_RS06950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OM951_RS06955	COG3328	transposase activity
OM951_RS06975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OM951_RS06975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OM951_RS06980	COG1105	Belongs to the carbohydrate kinase PfkB family
OM951_RS06985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OM951_RS06985	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM951_RS06990	COG1609	Transcriptional regulator
OM951_RS06995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM951_RS07000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM951_RS07010	COG2902	Dehydrogenase
OM951_RS07040	COG0840	transmembrane signaling receptor activity
OM951_RS07045	COG0477	Major facilitator Superfamily
OM951_RS07055	COG0784	Response regulator, receiver
OM951_RS07055	COG5002	protein histidine kinase activity
OM951_RS07055	COG2205	protein histidine kinase activity
OM951_RS07060	COG2733	membrane
OM951_RS07070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OM951_RS07080	COG2223	nitrite transmembrane transporter activity
OM951_RS07085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OM951_RS07090	COG0243	molybdopterin cofactor binding
OM951_RS07100	COG0477	Major facilitator Superfamily
OM951_RS07105	COG2703	oxygen carrier activity
OM951_RS07115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM951_RS07120	COG0174	glutamine synthetase
OM951_RS07125	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OM951_RS07145	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OM951_RS07165	COG3842	ATPase activity
OM951_RS07170	COG1176	ABC-type spermidine putrescine transport system, permease component I
OM951_RS07175	COG1177	transmembrane transport
OM951_RS07180	COG1012	belongs to the aldehyde dehydrogenase family
OM951_RS07195	COG4535	Mg2 and Co2 transporter CorC
OM951_RS07205	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OM951_RS07215	COG1702	phosphate starvation-inducible protein PhoH
OM951_RS07220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM951_RS07235	COG0741	lytic transglycosylase activity
OM951_RS07240	COG0723	plastoquinol--plastocyanin reductase activity
OM951_RS07245	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OM951_RS07250	COG2857	Cytochrome c1
OM951_RS07255	COG0625	glutathione transferase activity
OM951_RS07260	COG2969	positive regulation of protein catabolic process
OM951_RS07290	COG0840	transmembrane signaling receptor activity
OM951_RS07295	COG0835	chemotaxis
OM951_RS07340	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM951_RS07350	COG1570	exodeoxyribonuclease VII activity
OM951_RS07355	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OM951_RS07360	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OM951_RS07360	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OM951_RS07365	COG0802	atpase or kinase
OM951_RS07370	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM951_RS07375	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OM951_RS07400	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS07405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM951_RS07410	COG0501	Belongs to the peptidase M48B family
OM951_RS07420	COG2081	HI0933 family
OM951_RS07425	COG4681	YaeQ
OM951_RS07435	COG0625	glutathione transferase activity
OM951_RS07445	COG3328	transposase activity
OM951_RS07470	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OM951_RS07475	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OM951_RS07480	COG0513	Belongs to the DEAD box helicase family
OM951_RS07485	COG0488	(ABC) transporter
OM951_RS07500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OM951_RS07505	COG0483	inositol monophosphate 1-phosphatase activity
OM951_RS07520	COG3300	MHYT domain
OM951_RS07520	COG5001	Diguanylate cyclase
OM951_RS07525	COG1509	lysine 2,3-aminomutase activity
OM951_RS07530	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OM951_RS07540	COG0402	S-adenosylhomocysteine deaminase activity
OM951_RS07545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OM951_RS07575	COG3039	Transposase
OM951_RS07605	COG4302	ethanolamine ammonia-lyase activity
OM951_RS07620	COG3328	transposase activity
OM951_RS07635	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OM951_RS07640	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OM951_RS07660	COG2166	iron-sulfur cluster assembly
OM951_RS07665	COG0215	cysteine-tRNA ligase activity
OM951_RS07675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OM951_RS07680	COG0137	argininosuccinate synthase activity
OM951_RS07690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM951_RS07695	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OM951_RS07705	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OM951_RS07710	COG0165	Argininosuccinate lyase
OM951_RS07720	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OM951_RS07725	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OM951_RS07755	COG1294	oxidase, subunit
OM951_RS07765	COG4988	ABC transporter
OM951_RS07770	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OM951_RS07780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM951_RS07805	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OM951_RS07825	COG4133	protoheme IX ABC transporter activity
OM951_RS07830	COG0436	Aminotransferase
OM951_RS07835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM951_RS07850	COG1187	pseudouridine synthase activity
OM951_RS07855	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OM951_RS07860	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OM951_RS07865	COG2350	Protein conserved in bacteria
OM951_RS07895	COG1175	transmembrane transport
OM951_RS07900	COG0395	ABC-type sugar transport system, permease component
OM951_RS07925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM951_RS07930	COG2957	Belongs to the agmatine deiminase family
OM951_RS07945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OM951_RS07950	COG0539	negative regulation of cytoplasmic translation
OM951_RS07955	COG0776	regulation of translation
OM951_RS07965	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
OM951_RS07970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM951_RS07980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OM951_RS07985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OM951_RS07985	COG0475	glutathione-regulated potassium exporter activity
OM951_RS07995	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OM951_RS08005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OM951_RS08005	COG0519	Catalyzes the synthesis of GMP from XMP
OM951_RS08035	COG3328	transposase activity
OM951_RS08050	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OM951_RS08060	COG2801	Transposase and inactivated derivatives
OM951_RS08070	COG3384	dioxygenase
OM951_RS08075	COG0604	alcohol dehydrogenase
OM951_RS08085	COG3002	Belongs to the UPF0753 family
OM951_RS08090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OM951_RS08095	COG0583	DNA-binding transcription factor activity
OM951_RS08125	COG2197	response regulator
OM951_RS08140	COG1335	isochorismatase
OM951_RS08155	COG2814	Major facilitator Superfamily
OM951_RS08175	COG1914	H( )-stimulated, divalent metal cation uptake system
OM951_RS08190	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OM951_RS08205	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OM951_RS08220	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS08225	COG1183	phosphatidylcholine synthase activity
OM951_RS08235	COG3243	poly(R)-hydroxyalkanoic acid synthase
OM951_RS08250	COG0723	plastoquinol--plastocyanin reductase activity
OM951_RS08250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM951_RS08260	COG2183	response to ionizing radiation
OM951_RS08265	COG2205	protein histidine kinase activity
OM951_RS08265	COG0784	Response regulator, receiver
OM951_RS08285	COG3328	transposase activity
OM951_RS08335	COG0800	Aldolase
OM951_RS08340	COG0129	dihydroxy-acid dehydratase activity
OM951_RS08345	COG0363	glucosamine-6-phosphate deaminase activity
OM951_RS08350	COG0837	glucose binding
OM951_RS08355	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OM951_RS08365	COG0354	folic acid binding
OM951_RS08380	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OM951_RS08395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OM951_RS08400	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OM951_RS08410	COG4591	ABC-type transport system involved in lipoprotein release permease component
OM951_RS08415	COG1136	(ABC) transporter
OM951_RS08430	COG0811	peptide transport
OM951_RS08440	COG1132	(ABC) transporter
OM951_RS08445	COG1663	tetraacyldisaccharide 4'-kinase activity
OM951_RS08450	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OM951_RS08455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OM951_RS08465	COG0322	excinuclease ABC activity
OM951_RS08470	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OM951_RS08495	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OM951_RS08515	COG1054	Belongs to the UPF0176 family
OM951_RS08525	COG3328	transposase activity
OM951_RS08530	COG3039	Transposase
OM951_RS08545	COG3064	Membrane
OM951_RS08550	COG0428	transporter
OM951_RS08560	COG2154	pterin-4-alpha-carbinolamine dehydratase
OM951_RS08600	COG0640	Transcriptional regulator
OM951_RS08725	COG3328	transposase activity
OM951_RS08745	COG1238	metal cluster binding
OM951_RS08805	COG4566	intracellular signal transduction
OM951_RS08815	COG5001	Diguanylate cyclase
OM951_RS08835	COG3685	Protein conserved in bacteria
OM951_RS08855	COG0243	molybdopterin cofactor binding
OM951_RS08865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM951_RS08870	COG2223	nitrite transmembrane transporter activity
OM951_RS08875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OM951_RS08885	COG1648	precorrin-2 dehydrogenase activity
OM951_RS08885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM951_RS08910	COG0746	molybdenum cofactor guanylyltransferase activity
OM951_RS08915	COG0303	'Molybdopterin
OM951_RS08925	COG0708	Exodeoxyribonuclease III
OM951_RS08940	COG3328	transposase activity
OM951_RS08975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OM951_RS08980	COG0303	'Molybdopterin
OM951_RS08985	COG1160	GTP binding
OM951_RS08990	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM951_RS09010	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OM951_RS09025	COG1024	Enoyl-CoA hydratase
OM951_RS09025	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM951_RS09030	COG0183	Belongs to the thiolase family
OM951_RS09035	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OM951_RS09040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OM951_RS09050	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OM951_RS09060	COG1674	ftsk spoiiie
OM951_RS09065	COG0492	ferredoxin-NADP+ reductase activity
OM951_RS09075	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OM951_RS09085	COG0542	response to heat
OM951_RS09105	COG0482	sulfurtransferase activity
OM951_RS09110	COG2915	High frequency lysogenization protein hflD homolog
OM951_RS09130	COG4585	Histidine kinase
OM951_RS09140	COG5002	protein histidine kinase activity
OM951_RS09160	COG0784	Response regulator, receiver
OM951_RS09160	COG0835	chemotaxis
OM951_RS09170	COG1558	bacterial-type flagellum-dependent cell motility
OM951_RS09175	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OM951_RS09185	COG4787	bacterial-type flagellum-dependent cell motility
OM951_RS09195	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
OM951_RS09200	COG1706	bacterial-type flagellum-dependent cell motility
OM951_RS09205	COG1705	Flagellar rod assembly protein muramidase FlgJ
OM951_RS09205	COG3951	Flagellar rod assembly protein muramidase FlgJ
OM951_RS09215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OM951_RS09225	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OM951_RS09250	COG2197	response regulator
OM951_RS09260	COG2201	protein-glutamate methylesterase activity
OM951_RS09280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM951_RS09285	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS09315	COG3328	transposase activity
OM951_RS09325	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OM951_RS09350	COG1677	Flagellar hook-basal body complex protein FliE
OM951_RS09400	COG3190	flagellar
OM951_RS09420	COG1684	flagellar biosynthetic protein fliR
OM951_RS09430	COG3039	Transposase
OM951_RS09450	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OM951_RS09480	COG0784	Response regulator, receiver
OM951_RS09480	COG2198	Histidine kinase
OM951_RS09480	COG0643	Histidine kinase
OM951_RS09500	COG3039	Transposase
OM951_RS09520	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OM951_RS09525	COG1360	Flagellar Motor Protein
OM951_RS09530	COG1192	Involved in chromosome partitioning
OM951_RS09535	COG0835	chemotaxis
OM951_RS09545	COG0745	RESPONSE REGULATOR receiver
OM951_RS09560	COG0840	transmembrane signaling receptor activity
OM951_RS09565	COG0840	transmembrane signaling receptor activity
OM951_RS09580	COG0840	transmembrane signaling receptor activity
OM951_RS09590	COG0840	transmembrane signaling receptor activity
OM951_RS09595	COG0840	transmembrane signaling receptor activity
OM951_RS09600	COG0840	transmembrane signaling receptor activity
OM951_RS09605	COG0840	transmembrane signaling receptor activity
OM951_RS09620	COG0840	transmembrane signaling receptor activity
OM951_RS09625	COG0840	transmembrane signaling receptor activity
OM951_RS09630	COG0840	transmembrane signaling receptor activity
OM951_RS09635	COG0840	transmembrane signaling receptor activity
OM951_RS09640	COG0840	transmembrane signaling receptor activity
OM951_RS09650	COG0835	chemotaxis
OM951_RS09660	COG0840	transmembrane signaling receptor activity
OM951_RS09670	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OM951_RS09675	COG2201	protein-glutamate methylesterase activity
OM951_RS09685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM951_RS09720	COG0318	PFAM AMP-dependent synthetase and ligase
OM951_RS09725	COG1024	Enoyl-CoA hydratase
OM951_RS09730	COG0784	Response regulator, receiver
OM951_RS09730	COG2198	Histidine kinase
OM951_RS09730	COG2205	protein histidine kinase activity
OM951_RS09735	COG0784	Response regulator, receiver
OM951_RS09735	COG2198	Histidine kinase
OM951_RS09735	COG2205	protein histidine kinase activity
OM951_RS09745	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OM951_RS09750	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OM951_RS09765	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OM951_RS09775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM951_RS09780	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OM951_RS09790	COG0505	Belongs to the CarA family
OM951_RS09795	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OM951_RS09800	COG2258	MOSC domain
OM951_RS09805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM951_RS09850	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OM951_RS09870	COG0277	FAD linked oxidase domain protein
OM951_RS09875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OM951_RS09885	COG0531	amino acid
OM951_RS09890	COG0531	amino acid
OM951_RS09895	COG0235	Class ii aldolase
OM951_RS09900	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OM951_RS09905	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
OM951_RS09920	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OM951_RS09920	COG0140	phosphoribosyl-ATP diphosphatase activity
OM951_RS09925	COG0107	imidazoleglycerol-phosphate synthase activity
OM951_RS09930	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OM951_RS09935	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OM951_RS09940	COG0131	Imidazoleglycerol-phosphate dehydratase
OM951_RS09940	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OM951_RS09945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM951_RS09950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OM951_RS09955	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OM951_RS09965	COG0124	histidyl-tRNA synthetase
OM951_RS09970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM951_RS10005	COG0460	homoserine dehydrogenase
OM951_RS10005	COG0527	aspartate kinase activity
OM951_RS10115	COG0531	amino acid
OM951_RS10130	COG0006	proline dipeptidase activity
OM951_RS10140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OM951_RS10155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM951_RS10160	COG3938	Belongs to the proline racemase family
OM951_RS10170	COG0552	protein localization to endoplasmic reticulum
OM951_RS10175	COG1194	a g-specific adenine glycosylase
OM951_RS10210	COG0322	excinuclease ABC activity
OM951_RS10225	COG3040	lipid binding
OM951_RS10235	COG1960	acyl-CoA dehydrogenase activity
OM951_RS10245	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OM951_RS10265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM951_RS10275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM951_RS10300	COG0438	transferase activity, transferring glycosyl groups
OM951_RS10310	COG0438	transferase activity, transferring glycosyl groups
OM951_RS10315	COG0438	transferase activity, transferring glycosyl groups
OM951_RS10365	COG0072	phenylalanine-tRNA ligase activity
OM951_RS10365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM951_RS10370	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OM951_RS10385	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OM951_RS10390	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OM951_RS10405	COG2211	Major facilitator Superfamily
OM951_RS10415	COG1082	Xylose isomerase domain protein TIM barrel
OM951_RS10455	COG1012	belongs to the aldehyde dehydrogenase family
OM951_RS10470	COG0167	dihydroorotate dehydrogenase activity
OM951_RS10475	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OM951_RS10480	COG0697	spore germination
OM951_RS10485	COG1794	racemase activity, acting on amino acids and derivatives
OM951_RS10500	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OM951_RS10510	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
OM951_RS10515	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM951_RS10520	COG2203	Gaf domain
OM951_RS10520	COG3706	GGDEF domain
OM951_RS10520	COG4251	negative regulation of phosphorylation
OM951_RS10520	COG5001	Diguanylate cyclase
OM951_RS10530	COG1472	Belongs to the glycosyl hydrolase 3 family
OM951_RS10550	COG0166	Belongs to the GPI family
OM951_RS10555	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OM951_RS10560	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OM951_RS10565	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OM951_RS10590	COG1469	GTP cyclohydrolase I activity
OM951_RS10595	COG3328	transposase activity
OM951_RS10610	COG0477	Major facilitator Superfamily
OM951_RS10615	COG2115	Belongs to the xylose isomerase family
OM951_RS10620	COG1070	Carbohydrate kinase
OM951_RS10630	COG1501	Belongs to the glycosyl hydrolase 31 family
OM951_RS10665	COG0800	Aldolase
OM951_RS10670	COG4948	Mandelate Racemase Muconate Lactonizing
OM951_RS10680	COG3734	2-keto-3-deoxy-galactonokinase
OM951_RS10685	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OM951_RS10695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OM951_RS10710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OM951_RS10715	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OM951_RS10730	COG0351	phosphomethylpyrimidine kinase
OM951_RS10755	COG0583	DNA-binding transcription factor activity
OM951_RS10760	COG1741	Belongs to the pirin family
OM951_RS10770	COG0582	viral genome integration into host DNA
OM951_RS10825	COG1196	nuclear chromosome segregation
OM951_RS10910	COG3179	chitinase
OM951_RS10965	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
OM951_RS11125	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OM951_RS11130	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OM951_RS11135	COG2137	regulation of response to DNA damage stimulus
OM951_RS11140	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OM951_RS11145	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OM951_RS11155	COG1546	Belongs to the CinA family
OM951_RS11160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OM951_RS11170	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OM951_RS11175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OM951_RS11185	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OM951_RS11190	COG1534	Rna-binding protein
OM951_RS11195	COG3737	Protein of unknown function (DUF498/DUF598)
OM951_RS11205	COG1238	metal cluster binding
OM951_RS11210	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OM951_RS11215	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OM951_RS11220	COG2840	Smr protein MutS2
OM951_RS11225	COG0585	pseudouridine synthase activity
OM951_RS11230	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OM951_RS11240	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OM951_RS11245	COG0148	phosphopyruvate hydratase activity
OM951_RS11255	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OM951_RS11260	COG0504	CTP synthase activity
OM951_RS11285	COG0306	phosphate transporter
OM951_RS11295	COG1253	flavin adenine dinucleotide binding
OM951_RS11310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM951_RS11325	COG1136	(ABC) transporter
OM951_RS11340	COG0438	transferase activity, transferring glycosyl groups
OM951_RS11350	COG2264	protein methyltransferase activity
OM951_RS11380	COG2244	polysaccharide biosynthetic process
OM951_RS11430	COG1595	DNA-templated transcription, initiation
OM951_RS11445	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OM951_RS11455	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OM951_RS11465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM951_RS11485	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
OM951_RS11490	COG4191	Histidine kinase
OM951_RS11490	COG0784	Response regulator, receiver
OM951_RS11510	COG0840	transmembrane signaling receptor activity
OM951_RS11535	COG0583	DNA-binding transcription factor activity
OM951_RS11540	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OM951_RS11545	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OM951_RS11560	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OM951_RS11565	COG0077	Prephenate dehydratase
OM951_RS11565	COG1605	Chorismate mutase
OM951_RS11570	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OM951_RS11575	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OM951_RS11580	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
OM951_RS11620	COG1228	amidohydrolase
OM951_RS11625	COG2986	histidine ammonia-lyase
OM951_RS11635	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OM951_RS11645	COG4993	Dehydrogenase
OM951_RS11655	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OM951_RS11665	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OM951_RS11670	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OM951_RS11675	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM951_RS11685	COG3115	cell septum assembly
OM951_RS11695	COG0359	binds to the 23S rRNA
OM951_RS11700	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OM951_RS11705	COG0360	Binds together with S18 to 16S ribosomal RNA
OM951_RS11710	COG0316	Belongs to the HesB IscA family
OM951_RS11715	COG0017	Asparaginyl-tRNA synthetase
OM951_RS11795	COG0288	reversible hydration of carbon dioxide
OM951_RS11800	COG0662	Cupin 2, conserved barrel domain protein
OM951_RS11810	COG3844	kynureninase activity
OM951_RS11815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM951_RS11825	COG2925	Exonuclease
OM951_RS11845	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OM951_RS11850	COG0116	Belongs to the methyltransferase superfamily
OM951_RS11850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OM951_RS11860	COG0488	(ABC) transporter
OM951_RS11895	COG0494	nUDIX hydrolase
OM951_RS11905	COG1024	Enoyl-CoA hydratase
OM951_RS11915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OM951_RS11920	COG0659	secondary active sulfate transmembrane transporter activity
OM951_RS11945	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OM951_RS11950	COG0573	inorganic phosphate transmembrane transporter activity
OM951_RS11955	COG0581	inorganic phosphate transmembrane transporter activity
OM951_RS11960	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OM951_RS11965	COG0704	Plays a role in the regulation of phosphate uptake
OM951_RS11975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OM951_RS11985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM951_RS11995	COG0557	exoribonuclease II activity
OM951_RS12010	COG1960	acyl-CoA dehydrogenase activity
OM951_RS12015	COG2226	methyltransferase
OM951_RS12020	COG0646	methionine synthase
OM951_RS12020	COG1410	methionine synthase
OM951_RS12025	COG0646	methionine synthase
OM951_RS12025	COG1410	methionine synthase
OM951_RS12035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM951_RS12065	COG2900	Belongs to the SlyX family
OM951_RS12080	COG0386	Belongs to the glutathione peroxidase family
OM951_RS12090	COG1725	Transcriptional regulator
OM951_RS12095	COG1131	(ABC) transporter
OM951_RS12145	COG2850	peptidyl-arginine hydroxylation
OM951_RS12180	COG1132	(ABC) transporter
OM951_RS12185	COG0583	DNA-binding transcription factor activity
OM951_RS12215	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
OM951_RS12220	COG0484	heat shock protein binding
OM951_RS12225	COG0443	Heat shock 70 kDa protein
OM951_RS12230	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OM951_RS12235	COG1420	regulation of RNA biosynthetic process
OM951_RS12240	COG0497	DNA recombination
OM951_RS12250	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM951_RS12265	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OM951_RS12290	COG3706	GGDEF domain
OM951_RS12335	COG0583	DNA-binding transcription factor activity
OM951_RS12350	COG0415	Belongs to the DNA photolyase family
OM951_RS12355	COG0305	Participates in initiation and elongation during chromosome replication
OM951_RS12365	COG0367	asparagine synthase
OM951_RS12380	COG1960	acyl-CoA dehydrogenase activity
OM951_RS12395	COG0084	hydrolase, TatD family'
OM951_RS12400	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OM951_RS12460	COG0386	Belongs to the glutathione peroxidase family
OM951_RS12465	COG0339	signal peptide processing
OM951_RS12495	COG3104	oligopeptide transport
OM951_RS12525	COG2814	Major facilitator Superfamily
OM951_RS12530	COG1566	PFAM secretion protein HlyD family protein
OM951_RS12565	COG3328	transposase activity
OM951_RS12570	COG2801	Transposase and inactivated derivatives
OM951_RS12600	COG3328	transposase activity
OM951_RS12625	COG4774	siderophore transport
OM951_RS12635	COG0367	asparagine synthase
OM951_RS12645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM951_RS12650	COG1393	Belongs to the ArsC family
OM951_RS12700	COG0052	Belongs to the universal ribosomal protein uS2 family
OM951_RS12705	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OM951_RS12715	COG0528	UMP kinase activity
OM951_RS12720	COG0233	cytoplasmic translational termination
OM951_RS12725	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OM951_RS12730	COG0575	Belongs to the CDS family
OM951_RS12735	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OM951_RS12740	COG0750	zinc metalloprotease
OM951_RS12755	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM951_RS12760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OM951_RS12765	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM951_RS12770	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM951_RS12785	COG0825	malonyl-CoA metabolic process
OM951_RS12800	COG1981	membrane
OM951_RS12820	COG1695	Transcriptional regulator
OM951_RS12840	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OM951_RS12850	COG2040	homocysteine
OM951_RS12855	COG0833	amino acid
OM951_RS12870	COG0346	lactoylglutathione lyase activity
OM951_RS12890	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM951_RS12890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM951_RS12900	COG2878	Part of a membrane complex involved in electron transport
OM951_RS12915	COG1595	DNA-templated transcription, initiation
OM951_RS12940	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OM951_RS12955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OM951_RS12960	COG0251	oxidation-reduction process
OM951_RS12970	COG0392	lysyltransferase activity
OM951_RS12970	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OM951_RS13005	COG2814	Major facilitator Superfamily
OM951_RS13010	COG1902	pentaerythritol trinitrate reductase activity
OM951_RS13020	COG2824	Alkylphosphonate utilization operon protein PhnA
OM951_RS13030	COG1047	Peptidyl-prolyl cis-trans
OM951_RS13035	COG1077	Cell shape determining protein MreB Mrl
OM951_RS13050	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OM951_RS13060	COG5487	UPF0391 membrane protein
OM951_RS13065	COG1451	nucleotide metabolic process
OM951_RS13085	COG0183	Belongs to the thiolase family
OM951_RS13120	COG1793	dna ligase
OM951_RS13120	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OM951_RS13130	COG1793	dna ligase
OM951_RS13135	COG1201	RNA secondary structure unwinding
OM951_RS13145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM951_RS13150	COG1278	Cold shock
OM951_RS13160	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OM951_RS13165	COG1472	Belongs to the glycosyl hydrolase 3 family
OM951_RS13170	COG3046	protein related to deoxyribodipyrimidine photolyase
OM951_RS13175	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
OM951_RS13180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OM951_RS13185	COG2954	triphosphatase activity
OM951_RS13190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OM951_RS13200	COG1381	Involved in DNA repair and RecF pathway recombination
OM951_RS13205	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OM951_RS13210	COG0571	ribonuclease III activity
OM951_RS13225	COG0481	GTPase activity
OM951_RS13230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM951_RS13245	COG1024	Enoyl-CoA hydratase
OM951_RS13245	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM951_RS13255	COG0457	Tetratricopeptide repeat
OM951_RS13265	COG0457	Tetratricopeptide repeat
OM951_RS13295	COG1960	acyl-CoA dehydrogenase activity
OM951_RS13315	COG3867	Arabinogalactan endo-beta-1,4-galactanase
OM951_RS13320	COG3250	beta-galactosidase activity
OM951_RS13365	COG2801	Transposase and inactivated derivatives
OM951_RS13375	COG3328	transposase activity
OM951_RS13400	COG0509	glycine decarboxylation via glycine cleavage system
OM951_RS13405	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OM951_RS13415	COG0330	HflC and HflK could
OM951_RS13420	COG1742	UPF0060 membrane protein
OM951_RS13425	COG3956	TIGRFAM MazG family protein
OM951_RS13435	COG0494	nUDIX hydrolase
OM951_RS13445	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OM951_RS13450	COG0837	glucose binding
OM951_RS13470	COG1388	LysM domain
OM951_RS13470	COG3858	chitin binding
OM951_RS13475	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OM951_RS13485	COG1472	Belongs to the glycosyl hydrolase 3 family
OM951_RS13495	COG3537	Alpha-1,2-mannosidase
OM951_RS13530	COG3142	Participates in the control of copper homeostasis
OM951_RS13535	COG1446	asparaginase
OM951_RS13560	COG0784	Response regulator, receiver
OM951_RS13560	COG0643	Histidine kinase
OM951_RS13560	COG2198	Histidine kinase
OM951_RS13565	COG0840	transmembrane signaling receptor activity
OM951_RS13570	COG0835	chemotaxis
OM951_RS13585	COG0189	ligase activity
OM951_RS13595	COG1397	ADP-ribosylglycohydrolase
OM951_RS13605	COG1199	ATP-dependent helicase activity
OM951_RS13615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM951_RS13620	COG1215	transferase activity, transferring glycosyl groups
OM951_RS13630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OM951_RS13645	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
OM951_RS13650	COG0535	radical SAM domain protein
OM951_RS13655	COG0535	radical SAM domain protein
OM951_RS13670	COG0837	glucose binding
OM951_RS13690	COG1643	Atp-dependent helicase
OM951_RS13695	COG0783	Belongs to the Dps family
OM951_RS13700	COG0514	ATP-dependent DNA helicase (RecQ)
OM951_RS13740	COG0840	transmembrane signaling receptor activity
OM951_RS13760	COG3920	Histidine kinase
OM951_RS13765	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OM951_RS13775	COG0602	queuosine metabolic process
OM951_RS13785	COG2885	chlorophyll binding
OM951_RS13790	COG0823	Involved in the tonB-independent uptake of proteins
OM951_RS13800	COG0848	biopolymer transport protein
OM951_RS13810	COG0824	Thioesterase
OM951_RS13815	COG2255	four-way junction helicase activity
OM951_RS13825	COG3158	transport of potassium into the cell
OM951_RS13830	COG0632	four-way junction helicase activity
OM951_RS13835	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OM951_RS13840	COG0217	transcriptional regulatory protein
OM951_RS13855	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OM951_RS13870	COG0477	Major facilitator Superfamily
OM951_RS13890	COG0657	acetylesterase activity
OM951_RS13890	COG2755	lipolytic protein G-D-S-L family
OM951_RS13910	COG0488	(ABC) transporter
OM951_RS13940	COG4651	solute:proton antiporter activity
OM951_RS13940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OM951_RS13965	COG4772	TonB-dependent receptor
OM951_RS13975	COG4264	IucA IucC family
OM951_RS13990	COG0019	diaminopimelate decarboxylase activity
OM951_RS14010	COG3328	transposase activity
OM951_RS14030	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OM951_RS14040	COG1492	cobalamin metabolic process
OM951_RS14050	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OM951_RS14075	COG4206	TonB-dependent receptor
OM951_RS14085	COG0542	response to heat
OM951_RS14130	COG1877	trehalose-phosphatase activity
OM951_RS14135	COG3387	PFAM Glycoside hydrolase 15-related
OM951_RS14155	COG0840	transmembrane signaling receptor activity
OM951_RS14160	COG3011	Protein conserved in bacteria
OM951_RS14175	COG0564	pseudouridine synthase activity
OM951_RS14180	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM951_RS14190	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OM951_RS14190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM951_RS14200	COG3328	transposase activity
OM951_RS14215	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OM951_RS14220	COG0045	succinate-CoA ligase (ADP-forming) activity
OM951_RS14265	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OM951_RS14270	COG0237	dephospho-CoA kinase activity
OM951_RS14295	COG0745	RESPONSE REGULATOR receiver
OM951_RS14305	COG0189	ligase activity
OM951_RS14320	COG3328	transposase activity
OM951_RS14345	COG2801	Transposase and inactivated derivatives
OM951_RS14375	COG3328	transposase activity
OM951_RS14380	COG0322	excinuclease ABC activity
OM951_RS14420	COG2801	Transposase and inactivated derivatives
OM951_RS14445	COG3039	Transposase
OM951_RS14450	COG3039	Transposase
OM951_RS14490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OM951_RS14495	COG1061	Type III restriction enzyme res subunit
OM951_RS14570	COG2022	thiamine diphosphate biosynthetic process
OM951_RS14575	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OM951_RS14580	COG0471	metal ion transport
OM951_RS14580	COG3273	potassium ion transport
OM951_RS14605	COG1970	mechanosensitive ion channel activity
OM951_RS14615	COG1609	Transcriptional regulator
OM951_RS14630	COG4948	Mandelate Racemase Muconate Lactonizing
OM951_RS14640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM951_RS14650	COG0308	aminopeptidase N
OM951_RS14655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM951_RS14665	COG0529	Catalyzes the synthesis of activated sulfate
OM951_RS14665	COG2895	sulfate adenylyltransferase (ATP) activity
OM951_RS14670	COG0175	sulfate reduction
OM951_RS14675	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OM951_RS14680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM951_RS14685	COG0175	sulfate reduction
OM951_RS14705	COG2198	Histidine kinase
OM951_RS14705	COG2205	protein histidine kinase activity
OM951_RS14705	COG0784	Response regulator, receiver
OM951_RS14720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM951_RS14720	COG1648	precorrin-2 dehydrogenase activity
OM951_RS14735	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
OM951_RS14740	COG3588	fructose-bisphosphate aldolase
OM951_RS14745	COG0469	pyruvate kinase activity
OM951_RS14755	COG0126	phosphoglycerate kinase activity
OM951_RS14785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OM951_RS14795	COG3047	cAMP biosynthetic process
OM951_RS14810	COG3453	Protein conserved in bacteria
OM951_RS14810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM951_RS14815	COG0725	ABC transporter, periplasmic molybdate-binding protein
OM951_RS14820	COG4149	molybdate abc transporter
OM951_RS14825	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OM951_RS14845	COG0642	Histidine kinase
OM951_RS14870	COG1022	Amp-dependent synthetase and ligase
OM951_RS14895	COG1376	ErfK ybiS ycfS ynhG family protein
OM951_RS14900	COG0739	heme binding
OM951_RS14905	COG4773	Receptor
OM951_RS14920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OM951_RS14925	COG1301	dicarboxylic acid transport
OM951_RS14935	COG2304	oxidoreductase activity
OM951_RS14955	COG0714	Associated with various cellular activities
OM951_RS14985	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OM951_RS15005	COG1957	nucleoside hydrolase
OM951_RS15010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OM951_RS15020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OM951_RS15035	COG1561	YicC-like family, N-terminal region
OM951_RS15040	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OM951_RS15050	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OM951_RS15055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OM951_RS15070	COG0006	proline dipeptidase activity
OM951_RS15080	COG0006	proline dipeptidase activity
OM951_RS15085	COG3079	Belongs to the UPF0149 family
OM951_RS15105	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OM951_RS15125	COG2912	Transglutaminase-like superfamily
OM951_RS15135	COG1773	rubredoxin
OM951_RS15140	COG0352	thiamine-phosphate diphosphorylase activity
OM951_RS15160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OM951_RS15170	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
OM951_RS15175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM951_RS15215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OM951_RS15220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM951_RS15225	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS15235	COG0671	phosphoesterase, PA-phosphatase related
OM951_RS15245	COG3781	membrane
OM951_RS15255	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OM951_RS15260	COG0563	adenylate kinase activity
OM951_RS15275	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
OM951_RS15285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OM951_RS15305	COG3710	Transcriptional regulator
OM951_RS15310	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OM951_RS15320	COG0840	transmembrane signaling receptor activity
OM951_RS15325	COG0405	Gamma-glutamyltransferase
OM951_RS15330	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OM951_RS15355	COG0473	3-isopropylmalate dehydrogenase activity
OM951_RS15360	COG0066	3-isopropylmalate dehydratase activity
OM951_RS15365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OM951_RS15385	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OM951_RS15390	COG1538	Outer membrane efflux protein
OM951_RS15395	COG1519	Transferase
OM951_RS15400	COG1560	Kdo2-lipid A biosynthetic process
OM951_RS15425	COG0280	phosphate acetyltransferase
OM951_RS15425	COG0281	malic enzyme
OM951_RS15460	COG2801	Transposase and inactivated derivatives
OM951_RS15470	COG0583	DNA-binding transcription factor activity
OM951_RS15475	COG0667	Aldo Keto reductase
OM951_RS15490	COG2197	response regulator
OM951_RS15500	COG0642	Histidine kinase
OM951_RS15515	COG2851	Citrate transporter
OM951_RS15520	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS15525	COG1609	Transcriptional regulator
OM951_RS15530	COG2211	Major facilitator Superfamily
OM951_RS15555	COG1162	GTPase activity
OM951_RS15560	COG0436	Aminotransferase
OM951_RS15575	COG0726	polysaccharide deacetylase
OM951_RS15580	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OM951_RS15595	COG3964	amidohydrolase
OM951_RS15600	COG0402	S-adenosylhomocysteine deaminase activity
OM951_RS15625	COG1307	EDD domain protein, DegV family
OM951_RS15640	COG2801	Transposase and inactivated derivatives
OM951_RS15650	COG3791	Glutathione-dependent formaldehyde-activating
OM951_RS15680	COG2205	protein histidine kinase activity
OM951_RS15695	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OM951_RS15710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OM951_RS15720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OM951_RS15725	COG1012	belongs to the aldehyde dehydrogenase family
OM951_RS15730	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
OM951_RS15755	COG1183	phosphatidylcholine synthase activity
OM951_RS15765	COG0442	prolyl-tRNA aminoacylation
OM951_RS15780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OM951_RS15785	COG1127	ABC transporter
OM951_RS15790	COG3218	ABC-type transport auxiliary lipoprotein component
OM951_RS15790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OM951_RS15820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OM951_RS15825	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
OM951_RS15825	COG0662	Cupin 2, conserved barrel domain protein
OM951_RS15855	COG2086	electron transfer activity
OM951_RS15870	COG0546	phosphoglycolate phosphatase activity
OM951_RS15870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OM951_RS15875	COG0277	FAD linked oxidase domain protein
OM951_RS15885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM951_RS15910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM951_RS15915	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
OM951_RS15920	COG0438	transferase activity, transferring glycosyl groups
OM951_RS15940	COG0438	transferase activity, transferring glycosyl groups
OM951_RS15945	COG0626	cystathionine gamma-synthase activity
OM951_RS15975	COG0625	glutathione transferase activity
OM951_RS15985	COG0513	Belongs to the DEAD box helicase family
OM951_RS15990	COG0720	synthase
OM951_RS16000	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OM951_RS16010	COG1956	GAF domain-containing protein
OM951_RS16025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OM951_RS16030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OM951_RS16040	COG4991	sh3 domain protein
OM951_RS16050	COG0339	signal peptide processing
OM951_RS16065	COG2132	Multicopper oxidase
OM951_RS16100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OM951_RS16105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM951_RS16110	COG1136	(ABC) transporter
OM951_RS16115	COG0577	efflux transmembrane transporter activity
OM951_RS16115	COG1136	(ABC) transporter
OM951_RS16135	COG4191	Histidine kinase
OM951_RS16140	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OM951_RS16165	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OM951_RS16170	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OM951_RS16175	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OM951_RS16180	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OM951_RS16185	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OM951_RS16200	COG0356	it plays a direct role in the translocation of protons across the membrane
OM951_RS16220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM951_RS16230	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM951_RS16270	COG2011	ABC-type metal ion transport system permease component
OM951_RS16275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OM951_RS16280	COG0697	spore germination
OM951_RS16285	COG1666	GTP binding
OM951_RS16295	COG2198	Histidine kinase
OM951_RS16295	COG0784	Response regulator, receiver
OM951_RS16295	COG5002	protein histidine kinase activity
OM951_RS16320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OM951_RS16325	COG1187	pseudouridine synthase activity
OM951_RS16330	COG2813	Specifically methylates the guanine in position
OM951_RS16335	COG3039	Transposase
OM951_RS16350	COG3328	transposase activity
OM951_RS16365	COG2205	protein histidine kinase activity
OM951_RS16365	COG2202	Pas domain
OM951_RS16385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OM951_RS16390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM951_RS16445	COG0842	Transport permease protein
OM951_RS16450	COG1131	(ABC) transporter
OM951_RS16455	COG0025	NhaP-type Na H and K H
OM951_RS16460	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
OM951_RS16465	COG1573	uracil-dna glycosylase
OM951_RS16475	COG3384	dioxygenase
OM951_RS16485	COG0583	DNA-binding transcription factor activity
OM951_RS16495	COG0667	Aldo Keto reductase
OM951_RS16510	COG3590	peptidase
OM951_RS16530	COG0531	amino acid
OM951_RS16545	COG2972	Histidine kinase
OM951_RS16565	COG3685	Protein conserved in bacteria
OM951_RS16570	COG3546	catalase activity
OM951_RS16620	COG1271	oxidase subunit
OM951_RS16625	COG1294	oxidase, subunit
OM951_RS16640	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS16660	COG1063	alcohol dehydrogenase
OM951_RS16735	COG0251	oxidation-reduction process
OM951_RS16765	COG0659	secondary active sulfate transmembrane transporter activity
OM951_RS16770	COG0038	chloride channel
OM951_RS16780	COG0024	Methionine aminopeptidase
OM951_RS16815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OM951_RS16820	COG1490	D-aminoacyl-tRNA deacylase activity
OM951_RS16825	COG1560	Kdo2-lipid A biosynthetic process
OM951_RS16870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OM951_RS16870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OM951_RS16875	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OM951_RS16880	COG0242	peptide deformylase activity
OM951_RS16885	COG1652	LysM domain
OM951_RS16890	COG0758	DNA mediated transformation
OM951_RS16910	COG1754	DNA topoisomerase type I activity
OM951_RS16910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM951_RS16915	COG0009	L-threonylcarbamoyladenylate synthase
OM951_RS16930	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS16940	COG0616	signal peptide processing
OM951_RS16945	COG0534	Mate efflux family protein
OM951_RS16970	COG0625	glutathione transferase activity
OM951_RS16985	COG1252	NADH dehydrogenase
OM951_RS16990	COG2860	membrane
OM951_RS16995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OM951_RS17000	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OM951_RS17005	COG2201	protein-glutamate methylesterase activity
OM951_RS17010	COG2177	Part of the ABC transporter FtsEX involved in
OM951_RS17015	COG2884	Cell division ATP-binding protein ftsE
OM951_RS17025	COG3118	belongs to the thioredoxin family
OM951_RS17030	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OM951_RS17040	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
OM951_RS17065	COG1652	LysM domain
OM951_RS17070	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OM951_RS17070	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OM951_RS17075	COG1473	amidohydrolase
OM951_RS17080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM951_RS17085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM951_RS17095	COG5383	Protein conserved in bacteria
OM951_RS17130	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
OM951_RS17135	COG3023	N-Acetylmuramoyl-L-alanine amidase
OM951_RS17145	COG4948	Mandelate Racemase Muconate Lactonizing
OM951_RS17155	COG0531	amino acid
OM951_RS17170	COG4682	membrane
OM951_RS17175	COG2133	pyrroloquinoline quinone binding
OM951_RS17185	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OM951_RS17190	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OM951_RS17205	COG1610	YqeY-like protein
OM951_RS17210	COG1295	ribonuclease BN
OM951_RS17215	COG0358	DNA primase activity
OM951_RS17230	COG0109	protoheme IX farnesyltransferase activity
OM951_RS17260	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
OM951_RS17275	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OM951_RS17315	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OM951_RS17320	COG0739	heme binding
OM951_RS17325	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OM951_RS17335	COG2223	nitrite transmembrane transporter activity
OM951_RS17340	COG0708	Exodeoxyribonuclease III
OM951_RS17345	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OM951_RS17355	COG1192	Involved in chromosome partitioning
OM951_RS17360	COG1475	DNA binding
OM951_RS17375	COG0463	Glycosyl transferase, family 2
OM951_RS17395	COG0756	dUTP diphosphatase activity
OM951_RS17400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OM951_RS17405	COG2003	Belongs to the UPF0758 family
OM951_RS17410	COG0018	arginyl-trna synthetase
OM951_RS17425	COG4221	oxidoreductase activity
OM951_RS17430	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OM951_RS17430	COG2755	lipolytic protein G-D-S-L family
OM951_RS17440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM951_RS17445	COG1166	arginine decarboxylase activity
OM951_RS17450	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OM951_RS17470	COG3291	Pkd domain containing protein
OM951_RS17470	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OM951_RS17485	COG0606	chelatase, subunit chli
OM951_RS17500	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OM951_RS17525	COG1690	Belongs to the RtcB family
OM951_RS17565	COG1090	epimerase
OM951_RS17575	COG0642	Histidine kinase
OM951_RS17595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM951_RS17620	COG1011	Hydrolase
OM951_RS17625	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OM951_RS17640	COG0753	catalase activity
OM951_RS17655	COG2197	response regulator
OM951_RS17660	COG4585	Histidine kinase
OM951_RS17665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM951_RS17670	COG1136	(ABC) transporter
OM951_RS17695	COG0697	spore germination
OM951_RS17720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM951_RS17725	COG0180	Tryptophanyl-tRNA synthetase
OM951_RS17730	COG3237	CsbD-like
OM951_RS17770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OM951_RS17785	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OM951_RS17790	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OM951_RS17790	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OM951_RS17800	COG3228	Belongs to the MtfA family
OM951_RS17830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM951_RS17875	COG1199	ATP-dependent helicase activity
OM951_RS17890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OM951_RS17980	COG4555	ABC transporter
OM951_RS17990	COG1476	TRANSCRIPTIONal
OM951_RS18010	COG1230	cation diffusion facilitator family transporter
OM951_RS18015	COG0543	2 iron, 2 sulfur cluster binding
OM951_RS18015	COG0633	Ferredoxin
OM951_RS18020	COG2801	Transposase and inactivated derivatives
OM951_RS18030	COG1131	(ABC) transporter
OM951_RS18035	COG0842	Transport permease protein
OM951_RS18040	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OM951_RS18065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM951_RS18085	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OM951_RS18090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OM951_RS18105	COG1042	CoA-binding domain protein
OM951_RS18105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM951_RS18105	COG0045	succinate-CoA ligase (ADP-forming) activity
OM951_RS18110	COG2239	Acts as a magnesium transporter
OM951_RS18115	COG3338	carbonate dehydratase activity
OM951_RS18130	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OM951_RS18135	COG3387	PFAM Glycoside hydrolase 15-related
OM951_RS18150	COG3100	YcgL domain-containing protein
OM951_RS18155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OM951_RS18175	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS18235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM951_RS18270	COG0408	coproporphyrinogen oxidase activity
OM951_RS18310	COG0631	protein serine/threonine phosphatase activity
OM951_RS18335	COG0667	Aldo Keto reductase
OM951_RS18340	COG0583	DNA-binding transcription factor activity
OM951_RS18415	COG0154	amidase activity
OM951_RS18440	COG3328	transposase activity
OM951_RS18520	COG0210	DNA helicase
OM951_RS18535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM951_RS18540	COG0583	DNA-binding transcription factor activity
OM951_RS18545	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OM951_RS18555	COG2159	amidohydrolase
OM951_RS18580	COG3328	transposase activity
OM951_RS18585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM951_RS18605	COG0357	Ribosomal RNA small subunit methyltransferase G
OM951_RS18610	COG3540	Alkaline phosphatase
OM951_RS18620	COG2091	lysine biosynthetic process via aminoadipic acid
OM951_RS18635	COG0708	Exodeoxyribonuclease III
OM951_RS18640	COG1940	carbohydrate kinase activity
OM951_RS18640	COG1846	Transcriptional regulator
OM951_RS18650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM951_RS18660	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM951_RS18665	COG3162	membrane
OM951_RS18675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OM951_RS18705	COG3507	Belongs to the glycosyl hydrolase 43 family
OM951_RS18725	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS18730	COG0179	Fumarylacetoacetate (FAA) hydrolase
OM951_RS18735	COG4948	Mandelate Racemase Muconate Lactonizing
OM951_RS18740	COG3254	rhamnose metabolic process
OM951_RS18745	COG0738	Major facilitator superfamily
OM951_RS18750	COG1414	Transcriptional regulator
OM951_RS18755	COG2207	Transcriptional regulator
OM951_RS18755	COG1917	Cupin 2, conserved barrel domain protein
OM951_RS18765	COG1971	Probably functions as a manganese efflux pump
OM951_RS18770	COG2205	protein histidine kinase activity
OM951_RS18780	COG3459	Glycosyltransferase 36 associated
OM951_RS18785	COG2211	Major facilitator Superfamily
OM951_RS18790	COG3265	gluconokinase activity
OM951_RS18795	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM951_RS18815	COG2911	Protein conserved in bacteria
OM951_RS18820	COG0729	surface antigen
OM951_RS18825	COG4771	TonB-dependent receptor
OM951_RS18830	COG0457	Tetratricopeptide repeat
OM951_RS18840	COG0752	glycyl-tRNA synthetase alpha subunit
OM951_RS18845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OM951_RS18860	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OM951_RS18860	COG0519	Catalyzes the synthesis of GMP from XMP
OM951_RS18875	COG0805	protein transport
OM951_RS18880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OM951_RS18885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OM951_RS18895	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OM951_RS18915	COG2974	May be involved in recombination
OM951_RS18920	COG0037	tRNA processing
OM951_RS18925	COG2115	Belongs to the xylose isomerase family
OM951_RS18935	COG3661	Belongs to the glycosyl hydrolase 67 family
OM951_RS18945	COG4948	Mandelate Racemase Muconate Lactonizing
OM951_RS18960	COG0246	Mannitol dehydrogenase
OM951_RS19015	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OM951_RS19040	COG3386	PFAM SMP-30 Gluconolaconase
OM951_RS19055	COG1904	glucuronate isomerase
OM951_RS19060	COG3693	PFAM glycoside hydrolase, family 10
OM951_RS19070	COG3039	Transposase
OM951_RS19080	COG3693	PFAM glycoside hydrolase, family 10
OM951_RS19095	COG2211	Major facilitator Superfamily
OM951_RS19110	COG3328	transposase activity
OM951_RS19155	COG2937	Belongs to the GPAT DAPAT family
OM951_RS19185	COG0284	orotidine-5'-phosphate decarboxylase activity
OM951_RS19190	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
OM951_RS19205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OM951_RS19255	COG0210	DNA helicase
OM951_RS19260	COG1435	thymidine kinase activity
OM951_RS19270	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
OM951_RS19280	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OM951_RS19310	COG3135	benzoate transporter
OM951_RS19335	COG0676	glucose-6-phosphate 1-epimerase activity
OM951_RS19345	COG3012	SEC-C Motif Domain Protein
OM951_RS19350	COG3328	transposase activity
OM951_RS19370	COG0302	gtp cyclohydrolase
OM951_RS19385	COG1566	PFAM secretion protein HlyD family protein
OM951_RS19395	COG1289	transmembrane transporter activity
OM951_RS19400	COG0477	Major facilitator Superfamily
OM951_RS19410	COG0583	DNA-binding transcription factor activity
OM951_RS19415	COG4221	oxidoreductase activity
OM951_RS19425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM951_RS19480	COG0564	pseudouridine synthase activity
OM951_RS19510	COG3012	SEC-C Motif Domain Protein
OM951_RS19580	COG4790	Type iii secretion
OM951_RS19735	COG3039	Transposase
OM951_RS19755	COG2801	Transposase and inactivated derivatives
OM951_RS19765	COG0511	ligase activity, forming carbon-carbon bonds
OM951_RS19770	COG0439	Biotin carboxylase
OM951_RS19795	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS19845	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OM951_RS19850	COG1074	ATP-dependent DNA helicase activity
OM951_RS19855	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OM951_RS19890	COG1127	ABC transporter
OM951_RS19895	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OM951_RS19900	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OM951_RS19915	COG2853	Lipoprotein
OM951_RS19930	COG0386	Belongs to the glutathione peroxidase family
OM951_RS19940	COG1322	Protein conserved in bacteria
OM951_RS19950	COG0583	DNA-binding transcription factor activity
OM951_RS19970	COG0531	amino acid
OM951_RS19975	COG3537	Alpha-1,2-mannosidase
OM951_RS19995	COG2199	diguanylate cyclase activity
OM951_RS19995	COG2203	Gaf domain
OM951_RS20000	COG3835	regulator
OM951_RS20005	COG1929	Belongs to the glycerate kinase type-1 family
OM951_RS20025	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OM951_RS20030	COG0861	Integral membrane protein TerC family
OM951_RS20040	COG0584	glycerophosphoryl diester phosphodiesterase
OM951_RS20055	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OM951_RS20060	COG0726	polysaccharide deacetylase
OM951_RS20070	COG0706	membrane insertase activity
OM951_RS20075	COG0594	ribonuclease P activity
OM951_RS20095	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OM951_RS20100	COG0187	DNA topoisomerase II activity
OM951_RS20110	COG0501	Belongs to the peptidase M48B family
OM951_RS20165	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS20170	COG0300	oxidoreductase activity
OM951_RS20190	COG1272	protein, Hemolysin III
OM951_RS20195	COG1111	helicase
OM951_RS20195	COG1205	dead DEAH box helicase
OM951_RS20285	COG0070	glutamate synthase
OM951_RS20285	COG0069	glutamate synthase activity
OM951_RS20285	COG0067	glutamate synthase
OM951_RS20290	COG0493	'glutamate synthase
OM951_RS20305	COG1064	alcohol dehydrogenase
OM951_RS20310	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM951_RS20320	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM951_RS20325	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM951_RS20335	COG2234	aminopeptidase activity
OM951_RS20345	COG4942	peptidase
OM951_RS20350	COG0793	Belongs to the peptidase S41A family
OM951_RS20395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM951_RS20405	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OM951_RS20420	COG3328	transposase activity
OM951_RS20425	COG2249	NAD(P)H dehydrogenase (quinone) activity
OM951_RS20435	COG3039	Transposase
OM951_RS20450	COG3039	Transposase
OM951_RS20460	COG3237	CsbD-like
OM951_RS20510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM951_RS20515	COG0477	Major facilitator Superfamily
OM951_RS20560	COG0714	Associated with various cellular activities
OM951_RS20610	COG4772	TonB-dependent receptor
OM951_RS20635	COG1304	FMN binding
OM951_RS20640	COG1755	Isoprenylcysteine carboxyl methyltransferase
OM951_RS20645	COG4585	Histidine kinase
OM951_RS20650	COG2197	response regulator
OM951_RS20675	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OM951_RS20720	COG2801	Transposase and inactivated derivatives
OM951_RS20730	COG3328	transposase activity
OM951_RS20740	COG0730	response to heat
OM951_RS20765	COG3039	Transposase
OM951_RS20785	COG3328	transposase activity
OM951_RS20800	COG3039	Transposase
OM951_RS20815	COG0366	Alpha amylase catalytic
OM951_RS20820	COG0366	Alpha amylase catalytic
OM951_RS20825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM951_RS20845	COG0657	acetylesterase activity
OM951_RS20845	COG2755	lipolytic protein G-D-S-L family
OM951_RS20855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OM951_RS20870	COG3507	Belongs to the glycosyl hydrolase 43 family
OM951_RS20875	COG1609	Transcriptional regulator
OM951_RS20880	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OM951_RS20885	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS20895	COG3039	Transposase
OM951_RS20905	COG2755	lipolytic protein G-D-S-L family
OM951_RS20915	COG3186	Phenylalanine-4-hydroxylase
OM951_RS20920	COG1522	sequence-specific DNA binding
OM951_RS20930	COG1752	Esterase of the alpha-beta hydrolase superfamily
OM951_RS20940	COG1119	ATPase activity
OM951_RS20955	COG1125	glycine betaine transport
OM951_RS20955	COG0517	IMP dehydrogenase activity
OM951_RS20970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM951_RS21000	COG0489	protein tyrosine kinase activity
OM951_RS21005	COG2062	phosphohistidine phosphatase, SixA
OM951_RS21015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM951_RS21055	COG1968	undecaprenyl-diphosphatase activity
OM951_RS21060	COG0174	glutamine synthetase
OM951_RS21065	COG0347	Belongs to the P(II) protein family
OM951_RS21070	COG0004	ammonium transporteR
OM951_RS21075	COG3852	Histidine kinase
OM951_RS21080	COG2204	response regulator
OM951_RS21085	COG2032	superoxide dismutase activity
OM951_RS21090	COG2032	superoxide dismutase activity
OM951_RS21105	COG0183	Belongs to the thiolase family
OM951_RS21140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM951_RS21145	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
OM951_RS21150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OM951_RS21175	COG2205	protein histidine kinase activity
OM951_RS21200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OM951_RS21215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM951_RS21220	COG3177	Filamentation induced by cAMP protein fic
OM951_RS21225	COG0596	Alpha beta hydrolase
OM951_RS21230	COG0727	PFAM Uncharacterised protein family (UPF0153)
OM951_RS21235	COG0318	PFAM AMP-dependent synthetase and ligase
OM951_RS21240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM951_RS21255	COG1181	Belongs to the D-alanine--D-alanine ligase family
OM951_RS21265	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OM951_RS21275	COG0564	pseudouridine synthase activity
OM951_RS21295	COG1446	asparaginase
OM951_RS21300	COG0339	signal peptide processing
OM951_RS21335	COG0475	glutathione-regulated potassium exporter activity
OM951_RS21340	COG0583	DNA-binding transcription factor activity
OM951_RS21345	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OM951_RS21350	COG2224	Isocitrate lyase
OM951_RS21390	COG4770	biotin carboxylase activity
OM951_RS21395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OM951_RS21400	COG1960	acyl-CoA dehydrogenase activity
OM951_RS21465	COG0697	spore germination
OM951_RS21475	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OM951_RS21480	COG1846	Transcriptional regulator
OM951_RS21485	COG1764	response to oxidative stress
OM951_RS21505	COG2130	NADP-dependent
OM951_RS21520	COG1187	pseudouridine synthase activity
OM951_RS21530	COG1643	Atp-dependent helicase
OM951_RS21535	COG4807	Protein conserved in bacteria
OM951_RS21545	COG2072	flavoprotein involved in K transport
OM951_RS21565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OM951_RS21575	COG0583	DNA-binding transcription factor activity
OM951_RS21610	COG2252	PERMEase
OM951_RS21630	COG0084	hydrolase, TatD family'
OM951_RS21645	COG0583	DNA-binding transcription factor activity
OM951_RS21650	COG2814	Major facilitator Superfamily
OM951_RS21665	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OM951_RS21670	COG1902	pentaerythritol trinitrate reductase activity
OM951_RS21690	COG0745	RESPONSE REGULATOR receiver
OM951_RS21695	COG2205	protein histidine kinase activity
OM951_RS21700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM951_RS21725	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OM951_RS21730	COG0583	DNA-binding transcription factor activity
OM951_RS21765	COG0702	epimerase
OM951_RS21770	COG1733	regulation of RNA biosynthetic process
OM951_RS21815	COG0129	dihydroxy-acid dehydratase activity
OM951_RS21830	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OM951_RS21890	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OM951_RS21915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OM951_RS21930	COG3485	protocatechuate 3,4-dioxygenase
OM951_RS21935	COG3485	protocatechuate 3,4-dioxygenase
OM951_RS21945	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM951_RS21950	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OM951_RS21960	COG1414	Transcriptional regulator
OM951_RS21970	COG0657	acetylesterase activity
OM951_RS21980	COG0445	tRNA wobble uridine modification
OM951_RS21990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OM951_RS22020	COG2267	carboxylic ester hydrolase activity
OM951_RS22030	COG0156	8-amino-7-oxononanoate synthase activity
OM951_RS22035	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OM951_RS22040	COG1040	competence protein
OM951_RS22045	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OM951_RS22065	COG3039	Transposase
OM951_RS22130	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OM951_RS22200	COG3264	Mechanosensitive ion channel
OM951_RS22200	COG1511	domain protein
OM951_RS22205	COG1368	sulfuric ester hydrolase activity
OM951_RS22210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OM951_RS22215	COG2354	Protein conserved in bacteria
OM951_RS22225	COG0297	glycogen (starch) synthase activity
OM951_RS22230	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM951_RS22235	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM951_RS22260	COG0702	epimerase
OM951_RS22270	COG1858	cytochrome C peroxidase
OM951_RS22280	COG2801	Transposase and inactivated derivatives
OM951_RS22290	COG3209	COG3209 Rhs family protein
OM951_RS22295	COG3039	Transposase
OM951_RS22305	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS22340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM951_RS22345	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_RS22355	COG0513	Belongs to the DEAD box helicase family
OM951_RS22360	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM951_RS22385	COG3483	tryptophan 2,3-dioxygenase activity
OM951_RS22390	COG2801	Transposase and inactivated derivatives
OM951_RS22410	COG3328	transposase activity
OM951_RS22615	COG4962	Type ii secretion system protein e
OM951_RS22630	COG3451	type IV secretory pathway VirB4
OM951_RS22645	COG3846	protein secretion by the type IV secretion system
OM951_RS22680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM951_RS22695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM951_RS22710	COG1487	ribonuclease activity
OM951_RS22715	COG4691	Plasmid stability protein
OM951_RS22720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OM951_RS22780	COG3328	transposase activity
OM951_RS22800	COG3328	transposase activity
OM951_RS22845	COG3328	transposase activity
OM951_RS22905	COG3328	transposase activity
OM951_RS22985	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OM951_RS22990	COG4691	Plasmid stability protein
OM951_RS22995	COG1487	ribonuclease activity