locus-tag	class	description
NG824_RS00010	COG0592	DNA-directed DNA polymerase activity
NG824_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NG824_RS00020	COG0187	DNA topoisomerase II activity
NG824_RS00025	COG1266	CAAX protease self-immunity
NG824_RS00030	COG0501	Belongs to the peptidase M48B family
NG824_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NG824_RS00095	COG0655	NAD(P)H dehydrogenase (quinone) activity
NG824_RS00125	COG4772	TonB-dependent receptor
NG824_RS00145	COG3284	Transcriptional regulator
NG824_RS00150	COG1012	belongs to the aldehyde dehydrogenase family
NG824_RS00180	COG1304	FMN binding
NG824_RS00185	COG2186	Transcriptional regulator
NG824_RS00200	COG4585	Histidine kinase
NG824_RS00205	COG2197	response regulator
NG824_RS00330	COG4771	TonB-dependent receptor
NG824_RS00335	COG4774	siderophore transport
NG824_RS00335	COG1629	transport
NG824_RS00365	COG2755	lipolytic protein G-D-S-L family
NG824_RS00365	COG0657	acetylesterase activity
NG824_RS00375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NG824_RS00390	COG1609	Transcriptional regulator
NG824_RS00400	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NG824_RS00405	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS00435	COG3186	Phenylalanine-4-hydroxylase
NG824_RS00440	COG1522	sequence-specific DNA binding
NG824_RS00460	COG1752	Esterase of the alpha-beta hydrolase superfamily
NG824_RS00470	COG0671	phosphoesterase, PA-phosphatase related
NG824_RS00480	COG0861	Integral membrane protein TerC family
NG824_RS00485	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NG824_RS00490	COG1929	Belongs to the glycerate kinase type-1 family
NG824_RS00505	COG0531	amino acid
NG824_RS00510	COG4566	intracellular signal transduction
NG824_RS00515	COG4191	Histidine kinase
NG824_RS00520	COG1285	pathogenesis
NG824_RS00530	COG1322	Protein conserved in bacteria
NG824_RS00535	COG0386	Belongs to the glutathione peroxidase family
NG824_RS00555	COG2853	Lipoprotein
NG824_RS00570	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NG824_RS00575	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NG824_RS00580	COG1127	ABC transporter
NG824_RS00620	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NG824_RS00625	COG1074	ATP-dependent DNA helicase activity
NG824_RS00630	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NG824_RS00690	COG0840	transmembrane signaling receptor activity
NG824_RS00700	COG0477	Major facilitator Superfamily
NG824_RS00705	COG0302	gtp cyclohydrolase
NG824_RS00735	COG2951	lytic endotransglycosylase activity
NG824_RS00755	COG3135	benzoate transporter
NG824_RS00795	COG1803	Methylglyoxal synthase
NG824_RS00800	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NG824_RS00805	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NG824_RS00820	COG0493	'glutamate synthase
NG824_RS00825	COG0067	glutamate synthase
NG824_RS00825	COG0069	glutamate synthase activity
NG824_RS00825	COG0070	glutamate synthase
NG824_RS00850	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS00885	COG1111	helicase
NG824_RS00885	COG1205	dead DEAH box helicase
NG824_RS00895	COG1272	protein, Hemolysin III
NG824_RS00935	COG2814	Major facilitator Superfamily
NG824_RS00985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NG824_RS00990	COG1192	Involved in chromosome partitioning
NG824_RS00995	COG2062	phosphohistidine phosphatase, SixA
NG824_RS01005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NG824_RS01010	COG2050	protein possibly involved in aromatic compounds catabolism
NG824_RS01035	COG1968	undecaprenyl-diphosphatase activity
NG824_RS01040	COG0174	glutamine synthetase
NG824_RS01045	COG0347	Belongs to the P(II) protein family
NG824_RS01050	COG0004	ammonium transporteR
NG824_RS01055	COG3852	Histidine kinase
NG824_RS01060	COG2204	response regulator
NG824_RS01065	COG2032	superoxide dismutase activity
NG824_RS01070	COG2032	superoxide dismutase activity
NG824_RS01085	COG0183	Belongs to the thiolase family
NG824_RS01110	COG0456	acetyltransferase
NG824_RS01125	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NG824_RS01130	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NG824_RS01140	COG3226	Transcriptional regulator
NG824_RS01150	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NG824_RS01160	COG0612	Peptidase, M16
NG824_RS01170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NG824_RS01180	COG0596	Alpha beta hydrolase
NG824_RS01185	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NG824_RS01200	COG0727	PFAM Uncharacterised protein family (UPF0153)
NG824_RS01205	COG0318	PFAM AMP-dependent synthetase and ligase
NG824_RS01220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NG824_RS01285	COG1595	DNA-templated transcription, initiation
NG824_RS01295	COG1446	asparaginase
NG824_RS01300	COG0339	signal peptide processing
NG824_RS01315	COG0681	Belongs to the peptidase S26 family
NG824_RS01335	COG0583	DNA-binding transcription factor activity
NG824_RS01340	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NG824_RS01345	COG2224	Isocitrate lyase
NG824_RS01350	COG3706	GGDEF domain
NG824_RS01370	COG4297	protein containing double-stranded beta helix domain
NG824_RS01375	COG0659	secondary active sulfate transmembrane transporter activity
NG824_RS01405	COG1024	Enoyl-CoA hydratase
NG824_RS01410	COG1022	Amp-dependent synthetase and ligase
NG824_RS01420	COG2814	Major facilitator Superfamily
NG824_RS01480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NG824_RS01490	COG3485	protocatechuate 3,4-dioxygenase
NG824_RS01495	COG3485	protocatechuate 3,4-dioxygenase
NG824_RS01505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NG824_RS01510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NG824_RS01520	COG2814	Major facilitator Superfamily
NG824_RS01525	COG1414	Transcriptional regulator
NG824_RS01530	COG2130	NADP-dependent
NG824_RS01545	COG1187	pseudouridine synthase activity
NG824_RS01555	COG1643	Atp-dependent helicase
NG824_RS01560	COG0084	hydrolase, TatD family'
NG824_RS01655	COG0842	Transport permease protein
NG824_RS01660	COG1131	(ABC) transporter
NG824_RS01665	COG0543	2 iron, 2 sulfur cluster binding
NG824_RS01665	COG0633	Ferredoxin
NG824_RS01675	COG1476	TRANSCRIPTIONal
NG824_RS01685	COG4555	ABC transporter
NG824_RS01710	COG0625	glutathione transferase activity
NG824_RS01765	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NG824_RS01795	COG1199	ATP-dependent helicase activity
NG824_RS01860	COG3511	phospholipase C
NG824_RS01870	COG0628	permease
NG824_RS01985	COG0754	glutathionylspermidine amidase activity
NG824_RS02010	COG0714	Associated with various cellular activities
NG824_RS02040	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NG824_RS02045	COG3420	alginic acid biosynthetic process
NG824_RS02060	COG0710	3-dehydroquinate dehydratase activity
NG824_RS02075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NG824_RS02080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NG824_RS02095	COG0657	acetylesterase activity
NG824_RS02110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NG824_RS02120	COG3023	N-Acetylmuramoyl-L-alanine amidase
NG824_RS02130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NG824_RS02160	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NG824_RS02165	COG1040	competence protein
NG824_RS02230	COG2815	serine threonine protein kinase
NG824_RS02230	COG0515	serine threonine protein kinase
NG824_RS02245	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NG824_RS02265	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NG824_RS02275	COG2960	long-chain fatty acid transporting porin activity
NG824_RS02295	COG1166	arginine decarboxylase activity
NG824_RS02300	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NG824_RS02300	COG2755	lipolytic protein G-D-S-L family
NG824_RS02305	COG0583	DNA-binding transcription factor activity
NG824_RS02340	COG4221	oxidoreductase activity
NG824_RS02355	COG2003	Belongs to the UPF0758 family
NG824_RS02360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NG824_RS02370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NG824_RS02380	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NG824_RS02385	COG0708	Exodeoxyribonuclease III
NG824_RS02390	COG2211	Major facilitator Superfamily
NG824_RS02405	COG0739	heme binding
NG824_RS02410	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NG824_RS02440	COG1064	alcohol dehydrogenase
NG824_RS02445	COG2234	aminopeptidase activity
NG824_RS02455	COG4942	peptidase
NG824_RS02460	COG0793	Belongs to the peptidase S41A family
NG824_RS02495	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NG824_RS02510	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NG824_RS02545	COG0840	transmembrane signaling receptor activity
NG824_RS02565	COG0358	DNA primase activity
NG824_RS02570	COG1295	ribonuclease BN
NG824_RS02590	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NG824_RS02595	COG0668	transmembrane transport
NG824_RS02600	COG2308	Evidence 4 Homologs of previously reported genes of
NG824_RS02615	COG4682	membrane
NG824_RS02620	COG2133	pyrroloquinoline quinone binding
NG824_RS02640	COG0531	amino acid
NG824_RS02655	COG1609	Transcriptional regulator
NG824_RS02680	COG1070	Carbohydrate kinase
NG824_RS02690	COG1472	Belongs to the glycosyl hydrolase 3 family
NG824_RS02700	COG3661	Belongs to the glycosyl hydrolase 67 family
NG824_RS02710	COG3507	Belongs to the glycosyl hydrolase 43 family
NG824_RS02715	COG1472	Belongs to the glycosyl hydrolase 3 family
NG824_RS02735	COG4948	Mandelate Racemase Muconate Lactonizing
NG824_RS02745	COG4771	TonB-dependent receptor
NG824_RS02750	COG3023	N-Acetylmuramoyl-L-alanine amidase
NG824_RS02775	COG3501	Rhs element vgr protein
NG824_RS02775	COG3409	Peptidoglycan-binding domain 1 protein
NG824_RS02810	COG5383	Protein conserved in bacteria
NG824_RS02815	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NG824_RS02820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NG824_RS02825	COG0628	permease
NG824_RS02850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NG824_RS02930	COG0708	Exodeoxyribonuclease III
NG824_RS02935	COG1418	mRNA catabolic process
NG824_RS02940	COG4807	Protein conserved in bacteria
NG824_RS02955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NG824_RS02990	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS02995	COG0179	Fumarylacetoacetate (FAA) hydrolase
NG824_RS03000	COG4948	Mandelate Racemase Muconate Lactonizing
NG824_RS03005	COG3254	rhamnose metabolic process
NG824_RS03010	COG0738	Major facilitator superfamily
NG824_RS03015	COG1414	Transcriptional regulator
NG824_RS03100	COG0626	cystathionine gamma-synthase activity
NG824_RS03115	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NG824_RS03145	COG2086	electron transfer activity
NG824_RS03170	COG0662	Cupin 2, conserved barrel domain protein
NG824_RS03170	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NG824_RS03175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NG824_RS03210	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NG824_RS03210	COG3218	ABC-type transport auxiliary lipoprotein component
NG824_RS03215	COG1127	ABC transporter
NG824_RS03220	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NG824_RS03235	COG0442	prolyl-tRNA aminoacylation
NG824_RS03245	COG1183	phosphatidylcholine synthase activity
NG824_RS03275	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NG824_RS03300	COG4974	Belongs to the 'phage' integrase family
NG824_RS03310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NG824_RS03315	COG0047	phosphoribosylformylglycinamidine synthase activity
NG824_RS03315	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NG824_RS03320	COG5295	Hep Hag repeat protein
NG824_RS03325	COG1404	Belongs to the peptidase S8 family
NG824_RS03330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NG824_RS03335	COG1459	type II secretion system
NG824_RS03340	COG2165	general secretion pathway protein
NG824_RS03345	COG4970	Tfp pilus assembly protein FimT
NG824_RS03350	COG2165	general secretion pathway protein
NG824_RS03355	COG4795	General secretion pathway protein
NG824_RS03360	COG3156	type II secretion system protein K
NG824_RS03365	COG3166	PFAM Fimbrial assembly family protein
NG824_RS03380	COG1450	Type ii and iii secretion system protein
NG824_RS03390	COG2188	Transcriptional regulator
NG824_RS03435	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NG824_RS03450	COG1215	transferase activity, transferring glycosyl groups
NG824_RS03455	COG1215	transferase activity, transferring glycosyl groups
NG824_RS03460	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NG824_RS03465	COG0457	Tetratricopeptide repeat
NG824_RS03470	COG0242	peptide deformylase activity
NG824_RS03475	COG0488	(ABC) transporter
NG824_RS03480	COG0477	Major facilitator Superfamily
NG824_RS03500	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NG824_RS03510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NG824_RS03510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NG824_RS03525	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NG824_RS03530	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NG824_RS03535	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NG824_RS03555	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NG824_RS03560	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NG824_RS03565	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NG824_RS03570	COG2205	protein histidine kinase activity
NG824_RS03575	COG0745	RESPONSE REGULATOR receiver
NG824_RS03580	COG0277	FAD linked oxidase domain protein
NG824_RS03585	COG1988	membrane-bound metal-dependent
NG824_RS03625	COG3116	cell division
NG824_RS03640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NG824_RS03660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NG824_RS03665	COG1181	Belongs to the D-alanine--D-alanine ligase family
NG824_RS03670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NG824_RS03680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NG824_RS03695	COG0739	heme binding
NG824_RS03700	COG0653	protein targeting
NG824_RS03710	COG0494	nUDIX hydrolase
NG824_RS03720	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NG824_RS03725	COG0366	Alpha amylase catalytic
NG824_RS03745	COG0840	transmembrane signaling receptor activity
NG824_RS03830	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NG824_RS03870	COG4106	trans-aconitate 2-methyltransferase activity
NG824_RS03875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NG824_RS03890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NG824_RS03895	COG0667	Aldo Keto reductase
NG824_RS03905	COG4771	TonB-dependent receptor
NG824_RS03925	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NG824_RS03930	COG4181	ATPase activity
NG824_RS03945	COG0642	Histidine kinase
NG824_RS03955	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NG824_RS03960	COG0861	Integral membrane protein TerC family
NG824_RS03965	COG1704	LemA family
NG824_RS03995	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NG824_RS04000	COG2967	ApaG domain
NG824_RS04010	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NG824_RS04015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NG824_RS04030	COG2096	Adenosyltransferase
NG824_RS04040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NG824_RS04045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NG824_RS04100	COG0697	spore germination
NG824_RS04125	COG0784	Response regulator, receiver
NG824_RS04125	COG2205	protein histidine kinase activity
NG824_RS04125	COG5002	protein histidine kinase activity
NG824_RS04130	COG2197	response regulator
NG824_RS04140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NG824_RS04175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NG824_RS04180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NG824_RS04185	COG0583	DNA-binding transcription factor activity
NG824_RS04190	COG3634	alkyl hydroperoxide reductase activity
NG824_RS04200	COG2890	protein-(glutamine-N5) methyltransferase activity
NG824_RS04250	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NG824_RS04250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NG824_RS04310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NG824_RS04315	COG1404	Belongs to the peptidase S8 family
NG824_RS04320	COG1404	Belongs to the peptidase S8 family
NG824_RS04325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NG824_RS04345	COG1295	ribonuclease BN
NG824_RS04350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NG824_RS04365	COG0521	Mo-molybdopterin cofactor biosynthetic process
NG824_RS04380	COG0456	acetyltransferase
NG824_RS04385	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NG824_RS04390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NG824_RS04405	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NG824_RS04415	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NG824_RS04425	COG0193	aminoacyl-tRNA hydrolase activity
NG824_RS04430	COG0012	GTP binding
NG824_RS04450	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NG824_RS04460	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NG824_RS04465	COG0250	Participates in transcription elongation, termination and antitermination
NG824_RS04480	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NG824_RS04485	COG0222	ribosome binding
NG824_RS04495	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NG824_RS04505	COG0049	tRNA binding
NG824_RS04510	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NG824_RS04515	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NG824_RS04520	COG0051	transcription antitermination factor activity, RNA binding
NG824_RS04530	COG0088	Forms part of the polypeptide exit tunnel
NG824_RS04535	COG0089	rRNA binding
NG824_RS04540	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NG824_RS04545	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NG824_RS04555	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NG824_RS04565	COG0255	Belongs to the universal ribosomal protein uL29 family
NG824_RS04570	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NG824_RS04580	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NG824_RS04585	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NG824_RS04590	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NG824_RS04605	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NG824_RS04615	COG1841	ribosomal large subunit assembly
NG824_RS04625	COG0201	protein transport
NG824_RS04630	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NG824_RS04640	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NG824_RS04650	COG0203	ribosomal protein L17
NG824_RS04670	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NG824_RS04685	COG1217	gtp-binding protein TYPA
NG824_RS04690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NG824_RS04710	COG0625	glutathione transferase activity
NG824_RS04740	COG0625	glutathione transferase activity
NG824_RS04760	COG0584	glycerophosphoryl diester phosphodiesterase
NG824_RS04785	COG0446	pyridine nucleotide-disulphide oxidoreductase
NG824_RS04785	COG1902	pentaerythritol trinitrate reductase activity
NG824_RS04790	COG0604	alcohol dehydrogenase
NG824_RS04795	COG0667	Aldo Keto reductase
NG824_RS04805	COG2814	Major facilitator Superfamily
NG824_RS04810	COG0583	DNA-binding transcription factor activity
NG824_RS04855	COG4208	sulfate ABC transporter
NG824_RS04860	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NG824_RS04880	COG0588	phosphoglycerate mutase activity
NG824_RS04885	COG0285	dihydrofolate synthase activity
NG824_RS04910	COG2833	Protein of unknown function (DUF455)
NG824_RS04915	COG3291	Pkd domain containing protein
NG824_RS04925	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NG824_RS04930	COG0671	phosphoesterase, PA-phosphatase related
NG824_RS04935	COG0438	transferase activity, transferring glycosyl groups
NG824_RS04940	COG0248	Ppx GppA phosphatase
NG824_RS04945	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NG824_RS04955	COG0745	RESPONSE REGULATOR receiver
NG824_RS04960	COG4783	chaperone-mediated protein folding
NG824_RS04975	COG0473	3-isopropylmalate dehydrogenase activity
NG824_RS05010	COG0544	peptidyl-prolyl cis-trans isomerase activity
NG824_RS05050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NG824_RS05065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NG824_RS05075	COG0328	RNA-DNA hybrid ribonuclease activity
NG824_RS05085	COG0631	protein serine/threonine phosphatase activity
NG824_RS05105	COG0859	PFAM glycosyl transferase family 9
NG824_RS05110	COG3642	lipopolysaccharide core region biosynthetic process
NG824_RS05115	COG1234	tRNA 3'-trailer cleavage
NG824_RS05120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NG824_RS05130	COG0315	cyclic pyranopterin monophosphate synthase activity
NG824_RS05135	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NG824_RS05140	COG0314	molybdopterin synthase activity
NG824_RS05160	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NG824_RS05175	COG0537	adenosine 5'-monophosphoramidase activity
NG824_RS05195	COG0714	Associated with various cellular activities
NG824_RS05220	COG1399	metal-binding, possibly nucleic acid-binding protein
NG824_RS05225	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NG824_RS05230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NG824_RS05235	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NG824_RS05240	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS05255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NG824_RS05260	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NG824_RS05265	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NG824_RS05290	COG2161	toxin-antitoxin pair type II binding
NG824_RS05295	COG0640	Transcriptional regulator
NG824_RS05305	COG0587	DNA-directed DNA polymerase activity
NG824_RS05320	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NG824_RS05375	COG2373	Large extracellular alpha-helical protein
NG824_RS05400	COG0577	efflux transmembrane transporter activity
NG824_RS05400	COG1136	(ABC) transporter
NG824_RS05420	COG4953	penicillin-binding protein 1C
NG824_RS05430	COG0678	peroxiredoxin activity
NG824_RS05450	COG0604	alcohol dehydrogenase
NG824_RS05455	COG0330	HflC and HflK could
NG824_RS05460	COG0330	HflC and HflK could
NG824_RS05470	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NG824_RS05565	COG1063	alcohol dehydrogenase
NG824_RS05570	COG0753	catalase activity
NG824_RS05575	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NG824_RS05575	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NG824_RS05580	COG2814	Major facilitator Superfamily
NG824_RS05600	COG2194	sulfuric ester hydrolase activity
NG824_RS05610	COG0745	RESPONSE REGULATOR receiver
NG824_RS05615	COG2205	protein histidine kinase activity
NG824_RS05625	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NG824_RS05630	COG2894	cell division
NG824_RS05635	COG0850	regulation of cytokinetic process
NG824_RS05645	COG4585	Histidine kinase
NG824_RS05650	COG2197	response regulator
NG824_RS05695	COG1073	alpha beta
NG824_RS05725	COG4638	Rieske (2fe-2S)
NG824_RS05730	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NG824_RS05750	COG0840	transmembrane signaling receptor activity
NG824_RS05765	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NG824_RS05780	COG1946	Acyl-CoA thioesterase
NG824_RS05785	COG1024	Enoyl-CoA hydratase
NG824_RS05795	COG0824	Thioesterase
NG824_RS05800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NG824_RS05805	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NG824_RS05810	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NG824_RS05815	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NG824_RS05830	COG0196	riboflavin kinase activity
NG824_RS05845	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NG824_RS05870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NG824_RS05875	COG1845	cytochrome c oxidase, subunit III
NG824_RS05880	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NG824_RS05885	COG1595	DNA-templated transcription, initiation
NG824_RS05890	COG0740	serine-type endopeptidase activity
NG824_RS05895	COG0793	Belongs to the peptidase S41A family
NG824_RS05935	COG0129	dihydroxy-acid dehydratase activity
NG824_RS05940	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS05955	COG1012	belongs to the aldehyde dehydrogenase family
NG824_RS05960	COG1879	ABC-type sugar transport system periplasmic component
NG824_RS05965	COG1129	ABC transporter
NG824_RS05970	COG1172	Belongs to the binding-protein-dependent transport system permease family
NG824_RS05975	COG1172	Belongs to the binding-protein-dependent transport system permease family
NG824_RS05980	COG0625	glutathione transferase activity
NG824_RS05990	COG0475	glutathione-regulated potassium exporter activity
NG824_RS06000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NG824_RS06020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NG824_RS06025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NG824_RS06050	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NG824_RS06060	COG0335	large ribosomal subunit rRNA binding
NG824_RS06065	COG0534	Mate efflux family protein
NG824_RS06080	COG0542	response to heat
NG824_RS06095	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NG824_RS06105	COG3250	beta-galactosidase activity
NG824_RS06110	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NG824_RS06125	COG2855	membrane
NG824_RS06140	COG1024	Enoyl-CoA hydratase
NG824_RS06140	COG1250	3-hydroxyacyl-CoA dehydrogenase
NG824_RS06155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NG824_RS06160	COG0481	GTPase activity
NG824_RS06165	COG0681	Belongs to the peptidase S26 family
NG824_RS06180	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NG824_RS06205	COG2954	triphosphatase activity
NG824_RS06210	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NG824_RS06215	COG1472	Belongs to the glycosyl hydrolase 3 family
NG824_RS06220	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NG824_RS06225	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NG824_RS06230	COG1278	Cold shock
NG824_RS06235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NG824_RS06245	COG1201	RNA secondary structure unwinding
NG824_RS06250	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NG824_RS06250	COG1793	dna ligase
NG824_RS06255	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NG824_RS06255	COG1793	dna ligase
NG824_RS06260	COG1960	acyl-CoA dehydrogenase activity
NG824_RS06290	COG0183	Belongs to the thiolase family
NG824_RS06310	COG1703	isobutyryl-CoA mutase activity
NG824_RS06310	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NG824_RS06310	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NG824_RS06345	COG5487	UPF0391 membrane protein
NG824_RS06360	COG4771	TonB-dependent receptor
NG824_RS06365	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NG824_RS06375	COG1187	pseudouridine synthase activity
NG824_RS06380	COG1451	nucleotide metabolic process
NG824_RS06390	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NG824_RS06420	COG1077	Cell shape determining protein MreB Mrl
NG824_RS06425	COG1047	Peptidyl-prolyl cis-trans
NG824_RS06435	COG2824	Alkylphosphonate utilization operon protein PhnA
NG824_RS06440	COG1902	pentaerythritol trinitrate reductase activity
NG824_RS06445	COG2814	Major facilitator Superfamily
NG824_RS06480	COG0392	lysyltransferase activity
NG824_RS06490	COG0251	oxidation-reduction process
NG824_RS06510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NG824_RS06535	COG1595	DNA-templated transcription, initiation
NG824_RS06550	COG2878	Part of a membrane complex involved in electron transport
NG824_RS06560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NG824_RS06560	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NG824_RS06570	COG0346	lactoylglutathione lyase activity
NG824_RS06580	COG2040	homocysteine
NG824_RS06590	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NG824_RS06605	COG2203	Gaf domain
NG824_RS06605	COG3706	GGDEF domain
NG824_RS06605	COG4251	negative regulation of phosphorylation
NG824_RS06605	COG5001	Diguanylate cyclase
NG824_RS06615	COG3118	belongs to the thioredoxin family
NG824_RS06625	COG0495	leucyl-tRNA aminoacylation
NG824_RS06640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NG824_RS06655	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NG824_RS06675	COG2968	Membrane
NG824_RS06695	COG0312	modulator of DNA gyrase
NG824_RS06700	COG3028	Belongs to the UPF0307 family
NG824_RS06705	COG0312	modulator of DNA gyrase
NG824_RS06730	COG4104	PAAR repeat-containing protein
NG824_RS06735	COG0142	geranyltranstransferase activity
NG824_RS06740	COG1722	exodeoxyribonuclease VII activity
NG824_RS06745	COG0037	tRNA processing
NG824_RS06755	COG1785	Belongs to the alkaline phosphatase family
NG824_RS06760	COG1301	dicarboxylic acid transport
NG824_RS06770	COG1607	acyl-coa hydrolase
NG824_RS06780	COG2226	methyltransferase
NG824_RS06785	COG0791	NLP P60 protein
NG824_RS06790	COG0791	NLP P60 protein
NG824_RS06800	COG2311	Membrane
NG824_RS06830	COG3590	peptidase
NG824_RS06845	COG4206	TonB-dependent receptor
NG824_RS06850	COG0457	Tetratricopeptide repeat
NG824_RS06860	COG4771	TonB-dependent receptor
NG824_RS06865	COG0489	protein tyrosine kinase activity
NG824_RS06870	COG0717	Belongs to the dCTP deaminase family
NG824_RS06875	COG1714	RDD family
NG824_RS06900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NG824_RS06915	COG0494	nUDIX hydrolase
NG824_RS06925	COG0433	COG0433 Predicted ATPase
NG824_RS06930	COG0741	lytic transglycosylase activity
NG824_RS06945	COG2890	protein-(glutamine-N5) methyltransferase activity
NG824_RS06950	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NG824_RS06960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NG824_RS06970	COG0101	tRNA pseudouridine synthase activity
NG824_RS06975	COG0135	phosphoribosylanthranilate isomerase activity
NG824_RS07010	COG0133	tryptophan synthase activity
NG824_RS07015	COG0159	tryptophan synthase activity
NG824_RS07035	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS07055	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NG824_RS07065	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NG824_RS07070	COG0649	NAD binding
NG824_RS07075	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NG824_RS07080	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NG824_RS07085	COG1034	ATP synthesis coupled electron transport
NG824_RS07120	COG1007	ATP synthesis coupled electron transport
NG824_RS07135	COG0195	Participates in both transcription termination and antitermination
NG824_RS07160	COG1185	polyribonucleotide nucleotidyltransferase activity
NG824_RS07165	COG3300	MHYT domain
NG824_RS07165	COG5001	Diguanylate cyclase
NG824_RS07175	COG1201	RNA secondary structure unwinding
NG824_RS07180	COG0840	transmembrane signaling receptor activity
NG824_RS07180	COG3290	protein histidine kinase activity
NG824_RS07185	COG0840	transmembrane signaling receptor activity
NG824_RS07185	COG3290	protein histidine kinase activity
NG824_RS07190	COG0835	chemotaxis
NG824_RS07235	COG1194	a g-specific adenine glycosylase
NG824_RS07240	COG0552	protein localization to endoplasmic reticulum
NG824_RS07250	COG3938	Belongs to the proline racemase family
NG824_RS07255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NG824_RS07270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NG824_RS07280	COG0006	proline dipeptidase activity
NG824_RS07295	COG0531	amino acid
NG824_RS07320	COG4206	TonB-dependent receptor
NG824_RS07330	COG3507	Belongs to the glycosyl hydrolase 43 family
NG824_RS07355	COG0326	Molecular chaperone. Has ATPase activity
NG824_RS07380	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NG824_RS07385	COG0405	Gamma-glutamyltransferase
NG824_RS07390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NG824_RS07395	COG0642	Histidine kinase
NG824_RS07405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NG824_RS07415	COG1538	Outer membrane efflux protein
NG824_RS07425	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NG824_RS07430	COG0840	transmembrane signaling receptor activity
NG824_RS07435	COG2146	nitrite reductase [NAD(P)H] activity
NG824_RS07445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NG824_RS07455	COG0396	ATPase activity
NG824_RS07475	COG0693	protein deglycase activity
NG824_RS07490	COG0739	heme binding
NG824_RS07505	COG1764	response to oxidative stress
NG824_RS07515	COG0384	phenazine biosynthesis protein PhzF
NG824_RS07555	COG0142	geranyltranstransferase activity
NG824_RS07560	COG0629	single-stranded DNA binding
NG824_RS07585	COG2010	Cytochrome c
NG824_RS07595	COG0673	inositol 2-dehydrogenase activity
NG824_RS07600	COG2211	Major facilitator Superfamily
NG824_RS07610	COG1609	Transcriptional regulator
NG824_RS07620	COG3104	oligopeptide transport
NG824_RS07630	COG0823	Involved in the tonB-independent uptake of proteins
NG824_RS07630	COG1506	peptidase
NG824_RS07665	COG1741	Belongs to the pirin family
NG824_RS07675	COG1741	Belongs to the pirin family
NG824_RS07685	COG0588	phosphoglycerate mutase activity
NG824_RS07695	COG2977	Belongs to the P-Pant transferase superfamily
NG824_RS07705	COG2211	Major facilitator Superfamily
NG824_RS07735	COG0840	transmembrane signaling receptor activity
NG824_RS07740	COG3290	protein histidine kinase activity
NG824_RS07740	COG0840	transmembrane signaling receptor activity
NG824_RS07745	COG0840	transmembrane signaling receptor activity
NG824_RS07750	COG0643	Histidine kinase
NG824_RS07750	COG2198	Histidine kinase
NG824_RS07760	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NG824_RS07770	COG3878	Protein conserved in bacteria
NG824_RS07775	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NG824_RS07785	COG0745	RESPONSE REGULATOR receiver
NG824_RS07790	COG2205	protein histidine kinase activity
NG824_RS07795	COG4452	Inner membrane protein CreD
NG824_RS07820	COG0735	belongs to the Fur family
NG824_RS07825	COG4650	regulator
NG824_RS07835	COG1690	Belongs to the RtcB family
NG824_RS07840	COG0430	RNA-3'-phosphate cyclase activity
NG824_RS07850	COG3214	Protein conserved in bacteria
NG824_RS07855	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NG824_RS07860	COG0746	molybdenum cofactor guanylyltransferase activity
NG824_RS07865	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NG824_RS07870	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NG824_RS07875	COG2080	2 iron, 2 sulfur cluster binding
NG824_RS07915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NG824_RS07965	COG1187	pseudouridine synthase activity
NG824_RS07995	COG1132	(ABC) transporter
NG824_RS08005	COG1862	Preprotein translocase
NG824_RS08010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NG824_RS08015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NG824_RS08020	COG0840	transmembrane signaling receptor activity
NG824_RS08045	COG1509	lysine 2,3-aminomutase activity
NG824_RS08055	COG3548	integral membrane protein
NG824_RS08060	COG0402	S-adenosylhomocysteine deaminase activity
NG824_RS08085	COG3706	GGDEF domain
NG824_RS08100	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NG824_RS08140	COG2166	iron-sulfur cluster assembly
NG824_RS08155	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NG824_RS08160	COG0137	argininosuccinate synthase activity
NG824_RS08170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NG824_RS08175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NG824_RS08185	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NG824_RS08190	COG0165	Argininosuccinate lyase
NG824_RS08205	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NG824_RS08230	COG1129	ABC transporter
NG824_RS08260	COG1294	oxidase, subunit
NG824_RS08275	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NG824_RS08285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NG824_RS08330	COG4133	protoheme IX ABC transporter activity
NG824_RS08335	COG0436	Aminotransferase
NG824_RS08405	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NG824_RS08410	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NG824_RS08415	COG2350	Protein conserved in bacteria
NG824_RS08450	COG0395	ABC-type sugar transport system, permease component
NG824_RS08460	COG0800	Aldolase
NG824_RS08465	COG0129	dihydroxy-acid dehydratase activity
NG824_RS08480	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NG824_RS08490	COG0354	folic acid binding
NG824_RS08505	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NG824_RS08530	COG4591	ABC-type transport system involved in lipoprotein release permease component
NG824_RS08535	COG1136	(ABC) transporter
NG824_RS08545	COG0658	competence protein
NG824_RS08545	COG2333	competence protein COMEC
NG824_RS08550	COG0811	peptide transport
NG824_RS08555	COG0848	biopolymer transport protein
NG824_RS08565	COG1663	tetraacyldisaccharide 4'-kinase activity
NG824_RS08575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NG824_RS08605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NG824_RS08615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NG824_RS08625	COG0673	inositol 2-dehydrogenase activity
NG824_RS08670	COG1914	H( )-stimulated, divalent metal cation uptake system
NG824_RS08685	COG4774	siderophore transport
NG824_RS08730	COG0348	domain, Protein
NG824_RS08745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NG824_RS08785	COG1309	transcriptional regulator
NG824_RS08790	COG0604	alcohol dehydrogenase
NG824_RS08795	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NG824_RS08800	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NG824_RS08810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NG824_RS08850	COG0577	efflux transmembrane transporter activity
NG824_RS08850	COG1136	(ABC) transporter
NG824_RS08880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NG824_RS08880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NG824_RS08885	COG1105	Belongs to the carbohydrate kinase PfkB family
NG824_RS08890	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NG824_RS08890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NG824_RS08895	COG1609	Transcriptional regulator
NG824_RS08910	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NG824_RS08915	COG0069	glutamate synthase activity
NG824_RS08920	COG3447	MASE1 domain protein
NG824_RS08920	COG5001	Diguanylate cyclase
NG824_RS08920	COG5002	protein histidine kinase activity
NG824_RS08960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NG824_RS08975	COG1253	flavin adenine dinucleotide binding
NG824_RS08985	COG0306	phosphate transporter
NG824_RS08995	COG2134	cdp-diacylglycerol pyrophosphatase
NG824_RS09020	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NG824_RS09030	COG0148	phosphopyruvate hydratase activity
NG824_RS09040	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NG824_RS09045	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NG824_RS09065	COG1595	DNA-templated transcription, initiation
NG824_RS09080	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NG824_RS09090	COG1238	metal cluster binding
NG824_RS09105	COG1534	Rna-binding protein
NG824_RS09110	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NG824_RS09115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NG824_RS09120	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NG824_RS09135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NG824_RS09140	COG1546	Belongs to the CinA family
NG824_RS09150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NG824_RS09155	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NG824_RS09160	COG2137	regulation of response to DNA damage stimulus
NG824_RS09165	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NG824_RS09170	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NG824_RS09215	COG1741	Belongs to the pirin family
NG824_RS09220	COG0583	DNA-binding transcription factor activity
NG824_RS09230	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS09250	COG0351	phosphomethylpyrimidine kinase
NG824_RS09250	COG0352	thiamine-phosphate diphosphorylase activity
NG824_RS09265	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NG824_RS09270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NG824_RS09280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NG824_RS09290	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NG824_RS09295	COG3734	2-keto-3-deoxy-galactonokinase
NG824_RS09305	COG4948	Mandelate Racemase Muconate Lactonizing
NG824_RS09310	COG0800	Aldolase
NG824_RS09335	COG1501	Belongs to the glycosyl hydrolase 31 family
NG824_RS09340	COG1070	Carbohydrate kinase
NG824_RS09345	COG2115	Belongs to the xylose isomerase family
NG824_RS09350	COG0477	Major facilitator Superfamily
NG824_RS09365	COG0617	tRNA 3'-terminal CCA addition
NG824_RS09370	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NG824_RS09375	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NG824_RS09390	COG0166	Belongs to the GPI family
NG824_RS09410	COG3209	COG3209 Rhs family protein
NG824_RS09435	COG1472	Belongs to the glycosyl hydrolase 3 family
NG824_RS09450	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NG824_RS09460	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NG824_RS09465	COG0671	phosphoesterase, PA-phosphatase related
NG824_RS09475	COG1794	racemase activity, acting on amino acids and derivatives
NG824_RS09485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NG824_RS09490	COG0167	dihydroorotate dehydrogenase activity
NG824_RS09505	COG1012	belongs to the aldehyde dehydrogenase family
NG824_RS09535	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NG824_RS09545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NG824_RS09550	COG0124	histidyl-tRNA synthetase
NG824_RS09565	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NG824_RS09570	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NG824_RS09585	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NG824_RS09600	COG0140	phosphoribosyl-ATP diphosphatase activity
NG824_RS09600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NG824_RS09620	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
NG824_RS09625	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NG824_RS09630	COG0235	Class ii aldolase
NG824_RS09635	COG0531	amino acid
NG824_RS09640	COG0531	amino acid
NG824_RS09650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NG824_RS09655	COG0277	FAD linked oxidase domain protein
NG824_RS09675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NG824_RS09695	COG1024	Enoyl-CoA hydratase
NG824_RS09715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NG824_RS09720	COG2258	MOSC domain
NG824_RS09730	COG0505	Belongs to the CarA family
NG824_RS09740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NG824_RS09745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NG824_RS09790	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NG824_RS09800	COG0784	Response regulator, receiver
NG824_RS09800	COG2198	Histidine kinase
NG824_RS09800	COG2205	protein histidine kinase activity
NG824_RS09805	COG1024	Enoyl-CoA hydratase
NG824_RS09810	COG0318	PFAM AMP-dependent synthetase and ligase
NG824_RS09815	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NG824_RS09820	COG1012	belongs to the aldehyde dehydrogenase family
NG824_RS09825	COG1309	transcriptional regulator
NG824_RS09830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NG824_RS09860	COG2201	protein-glutamate methylesterase activity
NG824_RS09875	COG0840	transmembrane signaling receptor activity
NG824_RS09880	COG0840	transmembrane signaling receptor activity
NG824_RS09885	COG0840	transmembrane signaling receptor activity
NG824_RS09895	COG0835	chemotaxis
NG824_RS09905	COG0840	transmembrane signaling receptor activity
NG824_RS09920	COG0840	transmembrane signaling receptor activity
NG824_RS09925	COG0840	transmembrane signaling receptor activity
NG824_RS09930	COG0840	transmembrane signaling receptor activity
NG824_RS09940	COG0840	transmembrane signaling receptor activity
NG824_RS09945	COG0840	transmembrane signaling receptor activity
NG824_RS09950	COG0840	transmembrane signaling receptor activity
NG824_RS09955	COG0840	transmembrane signaling receptor activity
NG824_RS09965	COG0745	RESPONSE REGULATOR receiver
NG824_RS09975	COG0835	chemotaxis
NG824_RS09980	COG1192	Involved in chromosome partitioning
NG824_RS09985	COG1360	Flagellar Motor Protein
NG824_RS09990	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NG824_RS09995	COG0643	Histidine kinase
NG824_RS09995	COG2198	Histidine kinase
NG824_RS09995	COG0784	Response regulator, receiver
NG824_RS10000	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NG824_RS10055	COG3190	flagellar
NG824_RS10095	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NG824_RS10105	COG1677	Flagellar hook-basal body complex protein FliE
NG824_RS10145	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS10150	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS10155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NG824_RS10175	COG2201	protein-glutamate methylesterase activity
NG824_RS10185	COG2197	response regulator
NG824_RS10210	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NG824_RS10215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NG824_RS10235	COG1706	bacterial-type flagellum-dependent cell motility
NG824_RS10240	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NG824_RS10250	COG4787	bacterial-type flagellum-dependent cell motility
NG824_RS10255	COG1749	Flagellar hook protein flgE
NG824_RS10265	COG1558	bacterial-type flagellum-dependent cell motility
NG824_RS10275	COG0784	Response regulator, receiver
NG824_RS10275	COG0835	chemotaxis
NG824_RS10295	COG4191	Histidine kinase
NG824_RS10320	COG1116	anion transmembrane transporter activity
NG824_RS10335	COG2915	High frequency lysogenization protein hflD homolog
NG824_RS10340	COG0482	sulfurtransferase activity
NG824_RS10360	COG0542	response to heat
NG824_RS10380	COG0492	ferredoxin-NADP+ reductase activity
NG824_RS10385	COG1674	ftsk spoiiie
NG824_RS10400	COG1230	cation diffusion facilitator family transporter
NG824_RS10405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NG824_RS10410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NG824_RS10450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NG824_RS10475	COG1404	Belongs to the peptidase S8 family
NG824_RS10485	COG1595	DNA-templated transcription, initiation
NG824_RS10535	COG2244	polysaccharide biosynthetic process
NG824_RS10575	COG0438	transferase activity, transferring glycosyl groups
NG824_RS10580	COG0438	transferase activity, transferring glycosyl groups
NG824_RS10600	COG1132	(ABC) transporter
NG824_RS10625	COG1136	(ABC) transporter
NG824_RS10650	COG0583	DNA-binding transcription factor activity
NG824_RS10655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NG824_RS10670	COG3552	Protein containing von Willebrand factor type A (VWA) domain
NG824_RS10680	COG0714	Associated with various cellular activities
NG824_RS10755	COG2205	protein histidine kinase activity
NG824_RS10825	COG2183	response to ionizing radiation
NG824_RS10830	COG4191	Histidine kinase
NG824_RS10830	COG0784	Response regulator, receiver
NG824_RS10850	COG1983	PspC domain protein
NG824_RS10860	COG3243	poly(R)-hydroxyalkanoic acid synthase
NG824_RS10870	COG1183	phosphatidylcholine synthase activity
NG824_RS10875	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS10915	COG0668	transmembrane transport
NG824_RS10920	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NG824_RS10930	COG1321	iron dependent repressor
NG824_RS10935	COG1914	H( )-stimulated, divalent metal cation uptake system
NG824_RS10975	COG5002	protein histidine kinase activity
NG824_RS10985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NG824_RS10990	COG3002	Belongs to the UPF0753 family
NG824_RS10995	COG1733	regulation of RNA biosynthetic process
NG824_RS11000	COG1247	-acetyltransferase
NG824_RS11015	COG0431	NADPH-dependent FMN reductase
NG824_RS11100	COG2948	multi-organism process
NG824_RS11115	COG3846	protein secretion by the type IV secretion system
NG824_RS11130	COG3451	type IV secretory pathway VirB4
NG824_RS11140	COG3838	Conjugal transfer protein Trbc
NG824_RS11145	COG4962	Type ii secretion system protein e
NG824_RS11175	COG0583	DNA-binding transcription factor activity
NG824_RS11215	COG0583	DNA-binding transcription factor activity
NG824_RS11240	COG1192	Involved in chromosome partitioning
NG824_RS11255	COG5489	Protein of unknown function (DUF736)
NG824_RS11290	COG2003	Belongs to the UPF0758 family
NG824_RS11325	COG0582	viral genome integration into host DNA
NG824_RS11330	COG0519	Catalyzes the synthesis of GMP from XMP
NG824_RS11330	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NG824_RS11340	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NG824_RS11350	COG1073	alpha beta
NG824_RS11355	COG0475	glutathione-regulated potassium exporter activity
NG824_RS11355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NG824_RS11360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NG824_RS11370	COG0746	molybdenum cofactor guanylyltransferase activity
NG824_RS11375	COG1160	GTP binding
NG824_RS11380	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NG824_RS11385	COG2976	Protein conserved in bacteria
NG824_RS11390	COG1426	Protein conserved in bacteria
NG824_RS11400	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NG824_RS11415	COG1024	Enoyl-CoA hydratase
NG824_RS11415	COG1250	3-hydroxyacyl-CoA dehydrogenase
NG824_RS11420	COG0183	Belongs to the thiolase family
NG824_RS11425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NG824_RS11435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NG824_RS11440	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NG824_RS11450	COG0776	regulation of translation
NG824_RS11460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NG824_RS11465	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NG824_RS11475	COG2957	Belongs to the agmatine deiminase family
NG824_RS11480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NG824_RS11490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NG824_RS11500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NG824_RS11520	COG0316	Belongs to the HesB IscA family
NG824_RS11520	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NG824_RS11535	COG0428	transporter
NG824_RS11540	COG3064	Membrane
NG824_RS11550	COG1530	ribonuclease E activity
NG824_RS11635	COG0583	DNA-binding transcription factor activity
NG824_RS11665	COG0077	Prephenate dehydratase
NG824_RS11665	COG1605	Chorismate mutase
NG824_RS11670	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NG824_RS11675	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NG824_RS11680	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NG824_RS11715	COG4221	oxidoreductase activity
NG824_RS11745	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NG824_RS11780	COG4993	Dehydrogenase
NG824_RS11790	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NG824_RS11800	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NG824_RS11810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NG824_RS11815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NG824_RS11850	COG0577	efflux transmembrane transporter activity
NG824_RS11855	COG0577	efflux transmembrane transporter activity
NG824_RS11860	COG3115	cell septum assembly
NG824_RS11870	COG0359	binds to the 23S rRNA
NG824_RS11875	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NG824_RS11885	COG0316	Belongs to the HesB IscA family
NG824_RS11910	COG2197	response regulator
NG824_RS11955	COG0288	reversible hydration of carbon dioxide
NG824_RS11970	COG3844	kynureninase activity
NG824_RS11980	COG2925	Exonuclease
NG824_RS12015	COG2902	Dehydrogenase
NG824_RS12025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NG824_RS12030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NG824_RS12035	COG1960	acyl-CoA dehydrogenase activity
NG824_RS12040	COG2226	methyltransferase
NG824_RS12050	COG1410	methionine synthase
NG824_RS12050	COG0646	methionine synthase
NG824_RS12075	COG2900	Belongs to the SlyX family
NG824_RS12090	COG0386	Belongs to the glutathione peroxidase family
NG824_RS12100	COG1725	Transcriptional regulator
NG824_RS12105	COG1131	(ABC) transporter
NG824_RS12125	COG0697	spore germination
NG824_RS12130	COG0436	Aminotransferase
NG824_RS12150	COG1253	flavin adenine dinucleotide binding
NG824_RS12165	COG2850	peptidyl-arginine hydroxylation
NG824_RS12215	COG1132	(ABC) transporter
NG824_RS12230	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NG824_RS12235	COG0484	heat shock protein binding
NG824_RS12240	COG0443	Heat shock 70 kDa protein
NG824_RS12245	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NG824_RS12250	COG1420	regulation of RNA biosynthetic process
NG824_RS12255	COG0497	DNA recombination
NG824_RS12260	COG0735	belongs to the Fur family
NG824_RS12265	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NG824_RS12280	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NG824_RS12325	COG3706	GGDEF domain
NG824_RS12360	COG0583	DNA-binding transcription factor activity
NG824_RS12365	COG2885	chlorophyll binding
NG824_RS12365	COG3047	cAMP biosynthetic process
NG824_RS12375	COG0415	Belongs to the DNA photolyase family
NG824_RS12385	COG0305	Participates in initiation and elongation during chromosome replication
NG824_RS12405	COG1960	acyl-CoA dehydrogenase activity
NG824_RS12420	COG0084	hydrolase, TatD family'
NG824_RS12425	COG4251	negative regulation of phosphorylation
NG824_RS12425	COG3706	GGDEF domain
NG824_RS12425	COG5001	Diguanylate cyclase
NG824_RS12425	COG2203	Gaf domain
NG824_RS12430	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NG824_RS12470	COG0625	glutathione transferase activity
NG824_RS12480	COG1595	DNA-templated transcription, initiation
NG824_RS12485	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NG824_RS12515	COG0386	Belongs to the glutathione peroxidase family
NG824_RS12520	COG0339	signal peptide processing
NG824_RS12580	COG1472	Belongs to the glycosyl hydrolase 3 family
NG824_RS12590	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NG824_RS12605	COG0488	(ABC) transporter
NG824_RS12610	COG0513	Belongs to the DEAD box helicase family
NG824_RS12630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NG824_RS12650	COG0625	glutathione transferase activity
NG824_RS12660	COG4681	YaeQ
NG824_RS12665	COG2081	HI0933 family
NG824_RS12685	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS12705	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NG824_RS12710	COG0860	N-Acetylmuramoyl-L-alanine amidase
NG824_RS12715	COG0802	atpase or kinase
NG824_RS12720	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NG824_RS12720	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NG824_RS12725	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NG824_RS12730	COG1570	exodeoxyribonuclease VII activity
NG824_RS12740	COG3040	lipid binding
NG824_RS12765	COG1846	Transcriptional regulator
NG824_RS12785	COG1404	Belongs to the peptidase S8 family
NG824_RS12790	COG1404	Belongs to the peptidase S8 family
NG824_RS12805	COG2815	serine threonine protein kinase
NG824_RS12805	COG0515	serine threonine protein kinase
NG824_RS12815	COG2197	response regulator
NG824_RS12820	COG1960	acyl-CoA dehydrogenase activity
NG824_RS12830	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NG824_RS12855	COG0438	transferase activity, transferring glycosyl groups
NG824_RS12865	COG0438	transferase activity, transferring glycosyl groups
NG824_RS12870	COG0438	transferase activity, transferring glycosyl groups
NG824_RS12915	COG0072	phenylalanine-tRNA ligase activity
NG824_RS12915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NG824_RS12920	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NG824_RS12925	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NG824_RS12935	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NG824_RS12965	COG1082	Xylose isomerase domain protein TIM barrel
NG824_RS12975	COG0366	Alpha amylase catalytic
NG824_RS13045	COG3505	Type IV secretory pathway VirD4
NG824_RS13105	COG3275	phosphorelay sensor kinase activity
NG824_RS13110	COG1611	Belongs to the LOG family
NG824_RS13120	COG2095	MarC family integral membrane protein
NG824_RS13125	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS13130	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NG824_RS13170	COG2969	positive regulation of protein catabolic process
NG824_RS13175	COG0625	glutathione transferase activity
NG824_RS13180	COG2857	Cytochrome c1
NG824_RS13185	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NG824_RS13190	COG0723	plastoquinol--plastocyanin reductase activity
NG824_RS13195	COG0741	lytic transglycosylase activity
NG824_RS13235	COG1702	phosphate starvation-inducible protein PhoH
NG824_RS13250	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NG824_RS13260	COG4535	Mg2 and Co2 transporter CorC
NG824_RS13275	COG1012	belongs to the aldehyde dehydrogenase family
NG824_RS13280	COG1177	transmembrane transport
NG824_RS13285	COG1176	ABC-type spermidine putrescine transport system, permease component I
NG824_RS13290	COG3842	ATPase activity
NG824_RS13330	COG0174	glutamine synthetase
NG824_RS13340	COG0174	glutamine synthetase
NG824_RS13345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NG824_RS13355	COG0477	Major facilitator Superfamily
NG824_RS13365	COG0243	molybdopterin cofactor binding
NG824_RS13370	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NG824_RS13380	COG2818	Glycosylase
NG824_RS13390	COG1309	transcriptional regulator
NG824_RS13405	COG1012	belongs to the aldehyde dehydrogenase family
NG824_RS13410	COG1396	sequence-specific DNA binding
NG824_RS13410	COG1917	Cupin 2, conserved barrel domain protein
NG824_RS13415	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NG824_RS13420	COG0686	Belongs to the AlaDH PNT family
NG824_RS13440	COG2733	membrane
NG824_RS13445	COG4999	Histidine kinase
NG824_RS13445	COG3850	Histidine kinase
NG824_RS13445	COG2205	protein histidine kinase activity
NG824_RS13445	COG3437	response regulator, receiver
NG824_RS13455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NG824_RS13455	COG0116	Belongs to the methyltransferase superfamily
NG824_RS13460	COG0488	(ABC) transporter
NG824_RS13505	COG1024	Enoyl-CoA hydratase
NG824_RS13515	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NG824_RS13525	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NG824_RS13530	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NG824_RS13535	COG0573	inorganic phosphate transmembrane transporter activity
NG824_RS13540	COG0581	inorganic phosphate transmembrane transporter activity
NG824_RS13550	COG0704	Plays a role in the regulation of phosphate uptake
NG824_RS13570	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NG824_RS13590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NG824_RS13600	COG0557	exoribonuclease II activity
NG824_RS13635	COG2814	Major facilitator Superfamily
NG824_RS13640	COG1566	PFAM secretion protein HlyD family protein
NG824_RS13650	COG1846	Transcriptional regulator
NG824_RS13685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NG824_RS13695	COG1070	Carbohydrate kinase
NG824_RS13745	COG0367	asparagine synthase
NG824_RS13750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NG824_RS13760	COG1393	Belongs to the ArsC family
NG824_RS13785	COG0024	Methionine aminopeptidase
NG824_RS13820	COG0052	Belongs to the universal ribosomal protein uS2 family
NG824_RS13835	COG0528	UMP kinase activity
NG824_RS13845	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NG824_RS13850	COG0575	Belongs to the CDS family
NG824_RS13855	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NG824_RS13860	COG0750	zinc metalloprotease
NG824_RS13870	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NG824_RS13875	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NG824_RS13880	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NG824_RS13920	COG1981	membrane
NG824_RS13975	COG3275	phosphorelay sensor kinase activity
NG824_RS13980	COG3279	Response regulator of the LytR AlgR family
NG824_RS14035	COG1477	protein flavinylation
NG824_RS14065	COG3178	'Phosphotransferase
NG824_RS14070	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NG824_RS14080	COG0628	permease
NG824_RS14105	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NG824_RS14140	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NG824_RS14155	COG1137	ATPase activity
NG824_RS14170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NG824_RS14180	COG1660	Displays ATPase and GTPase activities
NG824_RS14190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NG824_RS14195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NG824_RS14200	COG2239	Acts as a magnesium transporter
NG824_RS14225	COG1113	amino acid transport
NG824_RS14235	COG0840	transmembrane signaling receptor activity
NG824_RS14240	COG0840	transmembrane signaling receptor activity
NG824_RS14260	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NG824_RS14265	COG1678	Uncharacterized ACR, COG1678
NG824_RS14275	COG0519	Catalyzes the synthesis of GMP from XMP
NG824_RS14330	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NG824_RS14355	COG0477	Major facilitator Superfamily
NG824_RS14370	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NG824_RS14390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NG824_RS14400	COG1335	isochorismatase
NG824_RS14405	COG1609	Transcriptional regulator
NG824_RS14405	COG2207	Transcriptional regulator
NG824_RS14415	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NG824_RS14420	COG0477	Major facilitator Superfamily
NG824_RS14435	COG2353	YceI-like domain
NG824_RS14440	COG3038	cytochrome b561
NG824_RS14455	COG1760	l-serine dehydratase
NG824_RS14460	COG3706	GGDEF domain
NG824_RS14465	COG2267	carboxylic ester hydrolase activity
NG824_RS14480	COG0527	aspartate kinase activity
NG824_RS14480	COG0460	homoserine dehydrogenase
NG824_RS14485	COG0626	cystathionine gamma-synthase activity
NG824_RS14490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NG824_RS14495	COG0739	heme binding
NG824_RS14500	COG1725	Transcriptional regulator
NG824_RS14505	COG1131	(ABC) transporter
NG824_RS14515	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NG824_RS14520	COG1272	protein, Hemolysin III
NG824_RS14535	COG0517	IMP dehydrogenase activity
NG824_RS14540	COG0463	Glycosyl transferase, family 2
NG824_RS14545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NG824_RS14550	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NG824_RS14565	COG1309	transcriptional regulator
NG824_RS14575	COG1960	acyl-CoA dehydrogenase activity
NG824_RS14630	COG0330	HflC and HflK could
NG824_RS14645	COG3956	TIGRFAM MazG family protein
NG824_RS14650	COG1218	3'(2'),5'-bisphosphate nucleotidase
NG824_RS14655	COG0494	nUDIX hydrolase
NG824_RS14665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NG824_RS14670	COG0837	glucose binding
NG824_RS14685	COG3858	chitin binding
NG824_RS14685	COG1388	LysM domain
NG824_RS14690	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NG824_RS14700	COG1472	Belongs to the glycosyl hydrolase 3 family
NG824_RS14720	COG0531	amino acid
NG824_RS14730	COG1486	melibiose metabolic process
NG824_RS14740	COG3537	Alpha-1,2-mannosidase
NG824_RS14765	COG0604	alcohol dehydrogenase
NG824_RS14770	COG1733	regulation of RNA biosynthetic process
NG824_RS14845	COG1446	asparaginase
NG824_RS14870	COG2201	protein-glutamate methylesterase activity
NG824_RS14875	COG0643	Histidine kinase
NG824_RS14875	COG2198	Histidine kinase
NG824_RS14875	COG0784	Response regulator, receiver
NG824_RS14880	COG0840	transmembrane signaling receptor activity
NG824_RS14885	COG0835	chemotaxis
NG824_RS14900	COG0189	ligase activity
NG824_RS14920	COG0625	glutathione transferase activity
NG824_RS14925	COG1017	nitric oxide dioxygenase activity
NG824_RS14925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NG824_RS14935	COG1199	ATP-dependent helicase activity
NG824_RS14945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NG824_RS14950	COG1216	Glycosyl transferase, family 2
NG824_RS14960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NG824_RS14980	COG0535	radical SAM domain protein
NG824_RS15000	COG1643	Atp-dependent helicase
NG824_RS15005	COG0783	Belongs to the Dps family
NG824_RS15010	COG0514	ATP-dependent DNA helicase (RecQ)
NG824_RS15045	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NG824_RS15050	COG0602	queuosine metabolic process
NG824_RS15060	COG2885	chlorophyll binding
NG824_RS15075	COG0848	biopolymer transport protein
NG824_RS15085	COG0824	Thioesterase
NG824_RS15090	COG2255	four-way junction helicase activity
NG824_RS15095	COG3158	transport of potassium into the cell
NG824_RS15100	COG0632	four-way junction helicase activity
NG824_RS15140	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NG824_RS15165	COG0657	acetylesterase activity
NG824_RS15165	COG2755	lipolytic protein G-D-S-L family
NG824_RS15185	COG0488	(ABC) transporter
NG824_RS15220	COG4651	solute:proton antiporter activity
NG824_RS15220	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NG824_RS15230	COG4772	TonB-dependent receptor
NG824_RS15245	COG2814	Major facilitator Superfamily
NG824_RS15250	COG4264	IucA IucC family
NG824_RS15255	COG0019	diaminopimelate decarboxylase activity
NG824_RS15270	COG2223	nitrite transmembrane transporter activity
NG824_RS15290	COG0542	response to heat
NG824_RS15325	COG4771	TonB-dependent receptor
NG824_RS15335	COG3387	PFAM Glycoside hydrolase 15-related
NG824_RS15345	COG4993	Dehydrogenase
NG824_RS15350	COG0840	transmembrane signaling receptor activity
NG824_RS15375	COG0564	pseudouridine synthase activity
NG824_RS15380	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NG824_RS15390	COG1125	glycine betaine transport
NG824_RS15405	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NG824_RS15415	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NG824_RS15415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NG824_RS15420	COG4993	Dehydrogenase
NG824_RS15425	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NG824_RS15430	COG0045	succinate-CoA ligase (ADP-forming) activity
NG824_RS15460	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NG824_RS15475	COG0745	RESPONSE REGULATOR receiver
NG824_RS15485	COG0189	ligase activity
NG824_RS15495	COG3511	phospholipase C
NG824_RS15550	COG3273	potassium ion transport
NG824_RS15550	COG0471	metal ion transport
NG824_RS15565	COG0179	Fumarylacetoacetate (FAA) hydrolase
NG824_RS15580	COG1609	Transcriptional regulator
NG824_RS15615	COG0438	transferase activity, transferring glycosyl groups
NG824_RS15620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NG824_RS15635	COG0308	aminopeptidase N
NG824_RS15640	COG0529	Catalyzes the synthesis of activated sulfate
NG824_RS15640	COG2895	sulfate adenylyltransferase (ATP) activity
NG824_RS15645	COG0175	sulfate reduction
NG824_RS15650	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NG824_RS15655	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NG824_RS15660	COG0175	sulfate reduction
NG824_RS15680	COG1393	Belongs to the ArsC family
NG824_RS15685	COG5002	protein histidine kinase activity
NG824_RS15730	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NG824_RS15755	COG3588	fructose-bisphosphate aldolase
NG824_RS15765	COG0469	pyruvate kinase activity
NG824_RS15805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NG824_RS15810	COG3047	cAMP biosynthetic process
NG824_RS15815	COG3047	cAMP biosynthetic process
NG824_RS15850	COG0640	Transcriptional regulator
NG824_RS15860	COG0725	ABC transporter, periplasmic molybdate-binding protein
NG824_RS15865	COG4149	molybdate abc transporter
NG824_RS15870	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NG824_RS15935	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NG824_RS15940	COG1301	dicarboxylic acid transport
NG824_RS15975	COG0714	Associated with various cellular activities
NG824_RS16005	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NG824_RS16020	COG0254	rRNA binding
NG824_RS16030	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NG824_RS16040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NG824_RS16045	COG1758	RNA polymerase activity
NG824_RS16050	COG0194	GDP metabolic process
NG824_RS16055	COG1561	YicC-like family, N-terminal region
NG824_RS16060	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NG824_RS16065	COG0346	lactoylglutathione lyase activity
NG824_RS16075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NG824_RS16090	COG0006	proline dipeptidase activity
NG824_RS16095	COG0006	proline dipeptidase activity
NG824_RS16100	COG3079	Belongs to the UPF0149 family
NG824_RS16130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NG824_RS16140	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NG824_RS16155	COG1773	rubredoxin
NG824_RS16165	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NG824_RS16170	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
NG824_RS16180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NG824_RS16185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NG824_RS16190	COG0346	lactoylglutathione lyase activity
NG824_RS16210	COG0586	Pfam SNARE associated Golgi protein
NG824_RS16225	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NG824_RS16250	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NG824_RS16260	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NG824_RS16280	COG0823	Involved in the tonB-independent uptake of proteins
NG824_RS16280	COG1506	peptidase
NG824_RS16280	COG4946	Tricorn protease homolog
NG824_RS16290	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NG824_RS16295	COG0840	transmembrane signaling receptor activity
NG824_RS16305	COG0405	Gamma-glutamyltransferase
NG824_RS16310	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NG824_RS16330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NG824_RS16345	COG0066	3-isopropylmalate dehydratase activity
NG824_RS16350	COG0473	3-isopropylmalate dehydrogenase activity
NG824_RS16355	COG3706	GGDEF domain
NG824_RS16375	COG0300	oxidoreductase activity
NG824_RS16400	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NG824_RS16405	COG1538	Outer membrane efflux protein
NG824_RS16410	COG1519	Transferase
NG824_RS16440	COG0281	malic enzyme
NG824_RS16440	COG0280	phosphate acetyltransferase
NG824_RS16445	COG1301	dicarboxylic acid transport
NG824_RS16455	COG4191	Histidine kinase
NG824_RS16470	COG3292	Two component regulator propeller
NG824_RS16470	COG2205	protein histidine kinase activity
NG824_RS16470	COG3292	Two component regulator propeller
NG824_RS16470	COG2205	protein histidine kinase activity
NG824_RS16470	COG0745	RESPONSE REGULATOR receiver
NG824_RS16470	COG0745	RESPONSE REGULATOR receiver
NG824_RS16480	COG0642	Histidine kinase
NG824_RS16500	COG2851	Citrate transporter
NG824_RS16505	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS16515	COG2211	Major facilitator Superfamily
NG824_RS16555	COG1162	GTPase activity
NG824_RS16560	COG0436	Aminotransferase
NG824_RS16575	COG0726	polysaccharide deacetylase
NG824_RS16580	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NG824_RS16590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NG824_RS16595	COG0804	urea catabolic process
NG824_RS16620	COG1307	EDD domain protein, DegV family
NG824_RS16630	COG0697	spore germination
NG824_RS16640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NG824_RS16655	COG3791	Glutathione-dependent formaldehyde-activating
NG824_RS16660	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NG824_RS16675	COG2205	protein histidine kinase activity
NG824_RS16680	COG0393	Putative heavy-metal-binding
NG824_RS16710	COG2207	Transcriptional regulator
NG824_RS16720	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NG824_RS16765	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NG824_RS16770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NG824_RS16775	COG1609	Transcriptional regulator
NG824_RS16780	COG0738	Major facilitator superfamily
NG824_RS16785	COG2188	Transcriptional regulator
NG824_RS16795	COG4305	rare lipoprotein A
NG824_RS16810	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS16815	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NG824_RS16825	COG4191	Histidine kinase
NG824_RS16830	COG0784	Response regulator, receiver
NG824_RS16835	COG2205	protein histidine kinase activity
NG824_RS16845	COG2823	Periplasmic or secreted lipoprotein
NG824_RS16850	COG0673	inositol 2-dehydrogenase activity
NG824_RS16855	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NG824_RS16865	COG1090	epimerase
NG824_RS16895	COG1051	belongs to the nudix hydrolase family
NG824_RS16895	COG1056	cytidyltransferase-related domain
NG824_RS16910	COG0583	DNA-binding transcription factor activity
NG824_RS16945	COG1686	Belongs to the peptidase S11 family
NG824_RS16955	COG2951	lytic endotransglycosylase activity
NG824_RS16960	COG1012	belongs to the aldehyde dehydrogenase family
NG824_RS16975	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NG824_RS16980	COG5434	Belongs to the glycosyl hydrolase 28 family
NG824_RS16990	COG0772	Belongs to the SEDS family
NG824_RS16995	COG0768	penicillin binding
NG824_RS17005	COG1792	Involved in formation and maintenance of cell shape
NG824_RS17010	COG1077	Cell shape determining protein MreB Mrl
NG824_RS17015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NG824_RS17030	COG3284	Transcriptional regulator
NG824_RS17050	COG2010	Cytochrome c
NG824_RS17075	COG0508	dehydrogenase complex catalyzes the overall conversion of
NG824_RS17075	COG0596	Alpha beta hydrolase
NG824_RS17085	COG0308	aminopeptidase N
NG824_RS17095	COG2226	methyltransferase
NG824_RS17115	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NG824_RS17120	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NG824_RS17140	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NG824_RS17150	COG2832	Protein of unknown function (DUF454)
NG824_RS17160	COG0436	Aminotransferase
NG824_RS17170	COG1505	serine-type exopeptidase activity
NG824_RS17185	COG1733	regulation of RNA biosynthetic process
NG824_RS17200	COG0181	hydroxymethylbilane synthase activity
NG824_RS17220	COG1335	isochorismatase
NG824_RS17230	COG2204	response regulator
NG824_RS17240	COG0297	glycogen (starch) synthase activity
NG824_RS17250	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NG824_RS17280	COG1648	precorrin-2 dehydrogenase activity
NG824_RS17280	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NG824_RS17305	COG4191	Histidine kinase
NG824_RS17310	COG0028	Belongs to the TPP enzyme family
NG824_RS17335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NG824_RS17345	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS17350	COG3685	Protein conserved in bacteria
NG824_RS17355	COG3685	Protein conserved in bacteria
NG824_RS17360	COG3546	catalase activity
NG824_RS17370	COG0840	transmembrane signaling receptor activity
NG824_RS17390	COG2271	Major facilitator Superfamily
NG824_RS17395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NG824_RS17420	COG1309	transcriptional regulator
NG824_RS17425	COG3038	cytochrome b561
NG824_RS17430	COG5002	protein histidine kinase activity
NG824_RS17440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NG824_RS17445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NG824_RS17465	COG1609	Transcriptional regulator
NG824_RS17490	COG1191	sigma factor activity
NG824_RS17545	COG0366	Alpha amylase catalytic
NG824_RS17550	COG0366	Alpha amylase catalytic
NG824_RS17555	COG3537	Alpha-1,2-mannosidase
NG824_RS17560	COG1609	Transcriptional regulator
NG824_RS17575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NG824_RS17580	COG1490	D-aminoacyl-tRNA deacylase activity
NG824_RS17595	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NG824_RS17630	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NG824_RS17635	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NG824_RS17635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NG824_RS17645	COG0242	peptide deformylase activity
NG824_RS17650	COG1652	LysM domain
NG824_RS17655	COG0758	DNA mediated transformation
NG824_RS17670	COG1714	RDD family
NG824_RS17675	COG1754	DNA topoisomerase type I activity
NG824_RS17675	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NG824_RS17680	COG0009	L-threonylcarbamoyladenylate synthase
NG824_RS17695	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS17705	COG0616	signal peptide processing
NG824_RS17710	COG0534	Mate efflux family protein
NG824_RS17720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NG824_RS17730	COG1252	NADH dehydrogenase
NG824_RS17735	COG2860	membrane
NG824_RS17740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NG824_RS17745	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NG824_RS17750	COG2201	protein-glutamate methylesterase activity
NG824_RS17755	COG2177	Part of the ABC transporter FtsEX involved in
NG824_RS17760	COG2884	Cell division ATP-binding protein ftsE
NG824_RS17770	COG3118	belongs to the thioredoxin family
NG824_RS17775	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NG824_RS17825	COG1518	maintenance of DNA repeat elements
NG824_RS17830	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NG824_RS17840	COG0673	inositol 2-dehydrogenase activity
NG824_RS17850	COG1501	Belongs to the glycosyl hydrolase 31 family
NG824_RS17855	COG2222	sugar isomerase
NG824_RS17860	COG1940	carbohydrate kinase activity
NG824_RS17870	COG1349	DNA-binding transcription factor activity
NG824_RS17885	COG1652	LysM domain
NG824_RS17895	COG1473	amidohydrolase
NG824_RS17900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NG824_RS17930	COG2852	Protein conserved in bacteria
NG824_RS17955	COG3483	tryptophan 2,3-dioxygenase activity
NG824_RS17995	COG0513	Belongs to the DEAD box helicase family
NG824_RS18005	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS18035	COG2354	Protein conserved in bacteria
NG824_RS18050	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NG824_RS18055	COG1196	nuclear chromosome segregation
NG824_RS18055	COG3264	Mechanosensitive ion channel
NG824_RS18060	COG0604	alcohol dehydrogenase
NG824_RS18070	COG0625	glutathione transferase activity
NG824_RS18080	COG0513	Belongs to the DEAD box helicase family
NG824_RS18085	COG0720	synthase
NG824_RS18095	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NG824_RS18100	COG1956	GAF domain-containing protein
NG824_RS18110	COG4206	TonB-dependent receptor
NG824_RS18120	COG0546	phosphoglycolate phosphatase activity
NG824_RS18125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NG824_RS18130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NG824_RS18145	COG0339	signal peptide processing
NG824_RS18150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NG824_RS18160	COG2217	Heavy metal translocating P-type atpase
NG824_RS18175	COG2132	Multicopper oxidase
NG824_RS18205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NG824_RS18215	COG1136	(ABC) transporter
NG824_RS18220	COG1136	(ABC) transporter
NG824_RS18220	COG0577	efflux transmembrane transporter activity
NG824_RS18225	COG0577	efflux transmembrane transporter activity
NG824_RS18230	COG0577	efflux transmembrane transporter activity
NG824_RS18240	COG1136	(ABC) transporter
NG824_RS18240	COG0577	efflux transmembrane transporter activity
NG824_RS18250	COG0577	efflux transmembrane transporter activity
NG824_RS18255	COG1136	(ABC) transporter
NG824_RS18255	COG0577	efflux transmembrane transporter activity
NG824_RS18260	COG1136	(ABC) transporter
NG824_RS18260	COG0577	efflux transmembrane transporter activity
NG824_RS18270	COG0577	efflux transmembrane transporter activity
NG824_RS18280	COG4191	Histidine kinase
NG824_RS18295	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NG824_RS18310	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NG824_RS18315	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NG824_RS18325	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NG824_RS18335	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NG824_RS18345	COG0356	it plays a direct role in the translocation of protons across the membrane
NG824_RS18365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NG824_RS18370	COG0508	dehydrogenase complex catalyzes the overall conversion of
NG824_RS18410	COG0697	spore germination
NG824_RS18445	COG0657	acetylesterase activity
NG824_RS18470	COG3485	protocatechuate 3,4-dioxygenase
NG824_RS18495	COG1187	pseudouridine synthase activity
NG824_RS18545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NG824_RS18605	COG0842	Transport permease protein
NG824_RS18610	COG1131	(ABC) transporter
NG824_RS18625	COG0025	NhaP-type Na H and K H
NG824_RS18645	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NG824_RS18650	COG1573	uracil-dna glycosylase
NG824_RS18660	COG3384	dioxygenase
NG824_RS18665	COG0583	DNA-binding transcription factor activity
NG824_RS18680	COG0667	Aldo Keto reductase
NG824_RS18690	COG0667	Aldo Keto reductase
NG824_RS18705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NG824_RS18710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NG824_RS18780	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NG824_RS18790	COG0531	amino acid
NG824_RS18810	COG5297	Belongs to the glycosyl hydrolase family 6
NG824_RS18810	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NG824_RS18815	COG5297	Belongs to the glycosyl hydrolase family 6
NG824_RS18815	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NG824_RS18820	COG0612	Peptidase, M16
NG824_RS18860	COG2207	Transcriptional regulator
NG824_RS18870	COG0598	Magnesium transport protein CorA
NG824_RS18875	COG1113	amino acid transport
NG824_RS18885	COG0697	spore germination
NG824_RS18905	COG0583	DNA-binding transcription factor activity
NG824_RS18910	COG2249	NAD(P)H dehydrogenase (quinone) activity
NG824_RS18925	COG2409	Drug exporters of the RND superfamily
NG824_RS18935	COG5520	Belongs to the glycosyl hydrolase 30 family
NG824_RS18945	COG3550	peptidyl-serine autophosphorylation
NG824_RS18960	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NG824_RS19075	COG2353	YceI-like domain
NG824_RS19080	COG0778	Nitroreductase
NG824_RS19100	COG0584	glycerophosphoryl diester phosphodiesterase
NG824_RS19115	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NG824_RS19120	COG0477	Major facilitator Superfamily
NG824_RS19125	COG2814	Major facilitator Superfamily
NG824_RS19130	COG0583	DNA-binding transcription factor activity
NG824_RS19150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NG824_RS19160	COG0459	protein refolding
NG824_RS19165	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NG824_RS19170	COG2356	endonuclease I
NG824_RS19175	COG1324	tolerance protein
NG824_RS19180	COG4232	protein-disulfide reductase activity
NG824_RS19185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NG824_RS19195	COG3291	Pkd domain containing protein
NG824_RS19195	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NG824_RS19200	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NG824_RS19205	COG0511	ligase activity, forming carbon-carbon bonds
NG824_RS19215	COG0439	Biotin carboxylase
NG824_RS19230	COG2264	protein methyltransferase activity
NG824_RS19245	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NG824_RS19250	COG4589	Belongs to the CDS family
NG824_RS19275	COG2453	phosphatase
NG824_RS19275	COG0671	phosphoesterase, PA-phosphatase related
NG824_RS19280	COG2267	carboxylic ester hydrolase activity
NG824_RS19285	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NG824_RS19290	COG0138	bifunctional purine biosynthesis protein purh
NG824_RS19300	COG0151	Belongs to the GarS family
NG824_RS19315	COG1289	transmembrane transporter activity
NG824_RS19320	COG2814	Major facilitator Superfamily
NG824_RS19370	COG2816	NAD+ diphosphatase activity
NG824_RS19375	COG0316	Belongs to the HesB IscA family
NG824_RS19400	COG0784	Response regulator, receiver
NG824_RS19400	COG2205	protein histidine kinase activity
NG824_RS19400	COG5002	protein histidine kinase activity
NG824_RS19420	COG1051	belongs to the nudix hydrolase family
NG824_RS19435	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NG824_RS19460	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NG824_RS19465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NG824_RS19470	COG0730	response to heat
NG824_RS19475	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NG824_RS19475	COG4124	Belongs to the glycosyl hydrolase 26 family
NG824_RS19485	COG0134	indole-3-glycerol-phosphate synthase activity
NG824_RS19490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NG824_RS19525	COG1597	lipid kinase activity
NG824_RS19535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NG824_RS19540	COG0484	heat shock protein binding
NG824_RS19575	COG2111	Na H antiporter
NG824_RS19575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NG824_RS19580	COG1006	Multisubunit Na H antiporter MnhC subunit
NG824_RS19585	COG0651	ATP synthesis coupled electron transport
NG824_RS19590	COG1863	multisubunit Na H antiporter MnhE subunit
NG824_RS19595	COG2212	antiporter activity
NG824_RS19600	COG1320	monovalent cation:proton antiporter activity
NG824_RS19605	COG0530	calcium, potassium:sodium antiporter activity
NG824_RS19610	COG0753	catalase activity
NG824_RS19630	COG2197	response regulator
NG824_RS19635	COG4585	Histidine kinase
NG824_RS19645	COG1131	(ABC) transporter
NG824_RS19650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NG824_RS19660	COG1136	(ABC) transporter
NG824_RS19665	COG0577	efflux transmembrane transporter activity
NG824_RS19685	COG0697	spore germination
NG824_RS19710	COG0180	Tryptophanyl-tRNA synthetase
NG824_RS19720	COG3237	CsbD-like
NG824_RS19735	COG0010	Belongs to the arginase family
NG824_RS19755	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NG824_RS19800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NG824_RS19840	COG2084	Dehydrogenase
NG824_RS19845	COG1902	pentaerythritol trinitrate reductase activity
NG824_RS19870	COG1404	Belongs to the peptidase S8 family
NG824_RS19880	COG2814	Major facilitator Superfamily
NG824_RS19885	COG0583	DNA-binding transcription factor activity
NG824_RS19900	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NG824_RS19905	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NG824_RS19930	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NG824_RS19935	COG1764	response to oxidative stress
NG824_RS19940	COG1846	Transcriptional regulator
NG824_RS19950	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NG824_RS19960	COG0697	spore germination
NG824_RS19965	COG0523	cobalamin synthesis protein
NG824_RS19995	COG1960	acyl-CoA dehydrogenase activity
NG824_RS20000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NG824_RS20040	COG0045	succinate-CoA ligase (ADP-forming) activity
NG824_RS20040	COG1042	CoA-binding domain protein
NG824_RS20040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NG824_RS20050	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NG824_RS20055	COG3387	PFAM Glycoside hydrolase 15-related
NG824_RS20060	COG0745	RESPONSE REGULATOR receiver
NG824_RS20075	COG1404	Belongs to the peptidase S8 family
NG824_RS20085	COG3100	YcgL domain-containing protein
NG824_RS20090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NG824_RS20100	COG0463	Glycosyl transferase, family 2
NG824_RS20115	COG1028	Short-chain dehydrogenase reductase Sdr
NG824_RS20140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NG824_RS20155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NG824_RS20190	COG1294	oxidase, subunit
NG824_RS20195	COG1271	oxidase subunit
NG824_RS20215	COG0408	coproporphyrinogen oxidase activity
NG824_RS20235	COG0589	response to stress
NG824_RS20255	COG3568	Endonuclease Exonuclease Phosphatase
NG824_RS20265	COG0392	lysyltransferase activity
NG824_RS20285	COG0210	DNA helicase
NG824_RS20290	COG0583	DNA-binding transcription factor activity
NG824_RS20295	COG0477	Major facilitator Superfamily
NG824_RS20305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NG824_RS20310	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NG824_RS20315	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NG824_RS20355	COG0463	Glycosyl transferase, family 2
NG824_RS20380	COG1192	Involved in chromosome partitioning
NG824_RS20385	COG0357	Ribosomal RNA small subunit methyltransferase G
NG824_RS20395	COG2091	lysine biosynthetic process via aminoadipic acid
NG824_RS20420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NG824_RS20435	COG1011	Hydrolase
NG824_RS20440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NG824_RS20480	COG0457	Tetratricopeptide repeat
NG824_RS20485	COG0784	Response regulator, receiver
NG824_RS20485	COG2198	Histidine kinase
NG824_RS20485	COG2205	protein histidine kinase activity
NG824_RS20490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NG824_RS20495	COG3265	gluconokinase activity
NG824_RS20500	COG2094	Belongs to the DNA glycosylase MPG family
NG824_RS20515	COG3209	COG3209 Rhs family protein
NG824_RS20535	COG2911	Protein conserved in bacteria
NG824_RS20540	COG0729	surface antigen
NG824_RS20555	COG3132	Protein of unknown function, DUF480
NG824_RS20605	COG3210	domain, Protein
NG824_RS20620	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NG824_RS20625	COG0284	orotidine-5'-phosphate decarboxylase activity
NG824_RS20655	COG2937	Belongs to the GPAT DAPAT family
NG824_RS20700	COG3046	protein related to deoxyribodipyrimidine photolyase
NG824_RS20725	COG0037	tRNA processing
NG824_RS20740	COG0840	transmembrane signaling receptor activity
NG824_RS20750	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NG824_RS20770	COG0805	protein transport
NG824_RS20780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NG824_RS20780	COG0519	Catalyzes the synthesis of GMP from XMP
NG824_RS20820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NG824_RS20835	COG0210	DNA helicase
NG824_RS20850	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NG824_RS20855	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NG824_RS20895	COG1119	ATPase activity
NG824_RS20900	COG1733	regulation of RNA biosynthetic process
NG824_RS20925	COG0594	ribonuclease P activity