locus-tag	class	description
SB85_RS00010	COG1125	glycine betaine transport
SB85_RS00020	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SB85_RS00025	COG0564	pseudouridine synthase activity
SB85_RS00050	COG0840	transmembrane signaling receptor activity
SB85_RS00060	COG3387	PFAM Glycoside hydrolase 15-related
SB85_RS00105	COG0542	response to heat
SB85_RS00130	COG2223	nitrite transmembrane transporter activity
SB85_RS00145	COG0019	diaminopimelate decarboxylase activity
SB85_RS00150	COG4264	IucA IucC family
SB85_RS00155	COG2814	Major facilitator Superfamily
SB85_RS00160	COG4264	IucA IucC family
SB85_RS00170	COG4772	TonB-dependent receptor
SB85_RS00180	COG4651	solute:proton antiporter activity
SB85_RS00180	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SB85_RS00210	COG0488	(ABC) transporter
SB85_RS00255	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SB85_RS00295	COG0632	four-way junction helicase activity
SB85_RS00300	COG3158	transport of potassium into the cell
SB85_RS00305	COG2255	four-way junction helicase activity
SB85_RS00310	COG0824	Thioesterase
SB85_RS00320	COG0848	biopolymer transport protein
SB85_RS00335	COG2885	chlorophyll binding
SB85_RS00345	COG0602	queuosine metabolic process
SB85_RS00350	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SB85_RS00380	COG0514	ATP-dependent DNA helicase (RecQ)
SB85_RS00385	COG0783	Belongs to the Dps family
SB85_RS00410	COG0535	radical SAM domain protein
SB85_RS00430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SB85_RS00440	COG0463	Glycosyl transferase, family 2
SB85_RS00445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SB85_RS00455	COG1199	ATP-dependent helicase activity
SB85_RS00480	COG0189	ligase activity
SB85_RS00495	COG0835	chemotaxis
SB85_RS00500	COG0840	transmembrane signaling receptor activity
SB85_RS00520	COG3209	COG3209 Rhs family protein
SB85_RS00525	COG1446	asparaginase
SB85_RS00590	COG1733	regulation of RNA biosynthetic process
SB85_RS00600	COG0488	(ABC) transporter
SB85_RS00645	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
SB85_RS00660	COG3537	Alpha-1,2-mannosidase
SB85_RS00670	COG1486	melibiose metabolic process
SB85_RS00680	COG0531	amino acid
SB85_RS00695	COG1472	Belongs to the glycosyl hydrolase 3 family
SB85_RS00705	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SB85_RS00710	COG1388	LysM domain
SB85_RS00710	COG3858	chitin binding
SB85_RS00725	COG0837	glucose binding
SB85_RS00730	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SB85_RS00740	COG0494	nUDIX hydrolase
SB85_RS00745	COG1218	3'(2'),5'-bisphosphate nucleotidase
SB85_RS00750	COG3956	TIGRFAM MazG family protein
SB85_RS00765	COG0330	HflC and HflK could
SB85_RS00815	COG1960	acyl-CoA dehydrogenase activity
SB85_RS00825	COG1309	transcriptional regulator
SB85_RS00850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SB85_RS00855	COG0463	Glycosyl transferase, family 2
SB85_RS00860	COG0517	IMP dehydrogenase activity
SB85_RS00870	COG1272	protein, Hemolysin III
SB85_RS00875	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SB85_RS00880	COG0739	heme binding
SB85_RS00885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SB85_RS00890	COG0626	cystathionine gamma-synthase activity
SB85_RS00895	COG0460	homoserine dehydrogenase
SB85_RS00895	COG0527	aspartate kinase activity
SB85_RS00900	COG2267	carboxylic ester hydrolase activity
SB85_RS00910	COG1760	l-serine dehydratase
SB85_RS00920	COG0625	glutathione transferase activity
SB85_RS00945	COG0352	thiamine-phosphate diphosphorylase activity
SB85_RS00945	COG0351	phosphomethylpyrimidine kinase
SB85_RS00960	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SB85_RS00965	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SB85_RS00975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SB85_RS00985	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
SB85_RS00990	COG3734	2-keto-3-deoxy-galactonokinase
SB85_RS01000	COG4948	Mandelate Racemase Muconate Lactonizing
SB85_RS01005	COG0800	Aldolase
SB85_RS01030	COG1501	Belongs to the glycosyl hydrolase 31 family
SB85_RS01035	COG1070	Carbohydrate kinase
SB85_RS01040	COG2115	Belongs to the xylose isomerase family
SB85_RS01045	COG0477	Major facilitator Superfamily
SB85_RS01060	COG0617	tRNA 3'-terminal CCA addition
SB85_RS01065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SB85_RS01070	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SB85_RS01085	COG0166	Belongs to the GPI family
SB85_RS01095	COG1472	Belongs to the glycosyl hydrolase 3 family
SB85_RS01110	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
SB85_RS01120	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SB85_RS01125	COG0671	phosphoesterase, PA-phosphatase related
SB85_RS01135	COG1794	racemase activity, acting on amino acids and derivatives
SB85_RS01145	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SB85_RS01150	COG0167	dihydroorotate dehydrogenase activity
SB85_RS01165	COG1012	belongs to the aldehyde dehydrogenase family
SB85_RS01195	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SB85_RS01205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SB85_RS01215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SB85_RS01220	COG0124	histidyl-tRNA synthetase
SB85_RS01235	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SB85_RS01240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SB85_RS01255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SB85_RS01270	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SB85_RS01270	COG0140	phosphoribosyl-ATP diphosphatase activity
SB85_RS01285	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SB85_RS01290	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SB85_RS01295	COG0235	Class ii aldolase
SB85_RS01300	COG0531	amino acid
SB85_RS01305	COG0531	amino acid
SB85_RS01315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SB85_RS01320	COG0277	FAD linked oxidase domain protein
SB85_RS01340	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SB85_RS01360	COG1024	Enoyl-CoA hydratase
SB85_RS01385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SB85_RS01390	COG2258	MOSC domain
SB85_RS01400	COG0505	Belongs to the CarA family
SB85_RS01410	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SB85_RS01415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SB85_RS01460	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SB85_RS01465	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SB85_RS01480	COG1024	Enoyl-CoA hydratase
SB85_RS01485	COG0318	PFAM AMP-dependent synthetase and ligase
SB85_RS01515	COG2201	protein-glutamate methylesterase activity
SB85_RS01525	COG0840	transmembrane signaling receptor activity
SB85_RS01530	COG0840	transmembrane signaling receptor activity
SB85_RS01535	COG0840	transmembrane signaling receptor activity
SB85_RS01545	COG0835	chemotaxis
SB85_RS01555	COG0840	transmembrane signaling receptor activity
SB85_RS01565	COG0840	transmembrane signaling receptor activity
SB85_RS01570	COG0840	transmembrane signaling receptor activity
SB85_RS01575	COG0840	transmembrane signaling receptor activity
SB85_RS01580	COG0840	transmembrane signaling receptor activity
SB85_RS01590	COG0840	transmembrane signaling receptor activity
SB85_RS01595	COG0840	transmembrane signaling receptor activity
SB85_RS01600	COG0840	transmembrane signaling receptor activity
SB85_RS01605	COG0840	transmembrane signaling receptor activity
SB85_RS01610	COG0840	transmembrane signaling receptor activity
SB85_RS01620	COG0745	RESPONSE REGULATOR receiver
SB85_RS01630	COG0835	chemotaxis
SB85_RS01640	COG1192	Involved in chromosome partitioning
SB85_RS01650	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SB85_RS01655	COG0643	Histidine kinase
SB85_RS01655	COG0784	Response regulator, receiver
SB85_RS01655	COG2198	Histidine kinase
SB85_RS01660	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
SB85_RS01750	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SB85_RS01760	COG1677	Flagellar hook-basal body complex protein FliE
SB85_RS01785	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS01790	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS01795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SB85_RS01815	COG2201	protein-glutamate methylesterase activity
SB85_RS01825	COG2197	response regulator
SB85_RS01850	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SB85_RS01855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SB85_RS01860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SB85_RS01885	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
SB85_RS01895	COG4787	bacterial-type flagellum-dependent cell motility
SB85_RS01900	COG1749	Flagellar hook protein flgE
SB85_RS01910	COG1558	bacterial-type flagellum-dependent cell motility
SB85_RS01920	COG0835	chemotaxis
SB85_RS01920	COG0784	Response regulator, receiver
SB85_RS01940	COG4191	Histidine kinase
SB85_RS01965	COG1116	anion transmembrane transporter activity
SB85_RS01985	COG2915	High frequency lysogenization protein hflD homolog
SB85_RS01990	COG0482	sulfurtransferase activity
SB85_RS02010	COG0542	response to heat
SB85_RS02045	COG0492	ferredoxin-NADP+ reductase activity
SB85_RS02050	COG1674	ftsk spoiiie
SB85_RS02065	COG1230	cation diffusion facilitator family transporter
SB85_RS02070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SB85_RS02075	COG0038	chloride channel
SB85_RS02110	COG0745	RESPONSE REGULATOR receiver
SB85_RS02125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SB85_RS02150	COG1404	Belongs to the peptidase S8 family
SB85_RS02160	COG1595	DNA-templated transcription, initiation
SB85_RS02210	COG2244	polysaccharide biosynthetic process
SB85_RS02215	COG1215	transferase activity, transferring glycosyl groups
SB85_RS02250	COG0438	transferase activity, transferring glycosyl groups
SB85_RS02275	COG1132	(ABC) transporter
SB85_RS02300	COG1136	(ABC) transporter
SB85_RS02325	COG0583	DNA-binding transcription factor activity
SB85_RS02330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SB85_RS02440	COG3039	Transposase
SB85_RS02455	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SB85_RS02465	COG0714	Associated with various cellular activities
SB85_RS02485	COG2205	protein histidine kinase activity
SB85_RS02550	COG0582	viral genome integration into host DNA
SB85_RS02580	COG5002	protein histidine kinase activity
SB85_RS02580	COG2205	protein histidine kinase activity
SB85_RS02580	COG0784	Response regulator, receiver
SB85_RS02585	COG2183	response to ionizing radiation
SB85_RS02590	COG4191	Histidine kinase
SB85_RS02590	COG0784	Response regulator, receiver
SB85_RS02600	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
SB85_RS02600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SB85_RS02610	COG1983	PspC domain protein
SB85_RS02620	COG3243	poly(R)-hydroxyalkanoic acid synthase
SB85_RS02630	COG1183	phosphatidylcholine synthase activity
SB85_RS02635	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS02660	COG0668	transmembrane transport
SB85_RS02665	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SB85_RS02675	COG1321	iron dependent repressor
SB85_RS02680	COG1914	H( )-stimulated, divalent metal cation uptake system
SB85_RS02740	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SB85_RS02745	COG3002	Belongs to the UPF0753 family
SB85_RS02750	COG1733	regulation of RNA biosynthetic process
SB85_RS02755	COG1247	-acetyltransferase
SB85_RS02770	COG0431	NADPH-dependent FMN reductase
SB85_RS02775	COG0519	Catalyzes the synthesis of GMP from XMP
SB85_RS02775	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SB85_RS02785	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SB85_RS02795	COG1073	alpha beta
SB85_RS02800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SB85_RS02800	COG0475	glutathione-regulated potassium exporter activity
SB85_RS02805	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SB85_RS02815	COG0746	molybdenum cofactor guanylyltransferase activity
SB85_RS02820	COG1160	GTP binding
SB85_RS02825	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SB85_RS02830	COG2976	Protein conserved in bacteria
SB85_RS02835	COG1426	Protein conserved in bacteria
SB85_RS02845	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SB85_RS02860	COG1024	Enoyl-CoA hydratase
SB85_RS02860	COG1250	3-hydroxyacyl-CoA dehydrogenase
SB85_RS02865	COG0183	Belongs to the thiolase family
SB85_RS02870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SB85_RS02880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SB85_RS02885	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
SB85_RS02895	COG0776	regulation of translation
SB85_RS02905	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SB85_RS02910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SB85_RS02920	COG2957	Belongs to the agmatine deiminase family
SB85_RS02925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SB85_RS02935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SB85_RS02945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SB85_RS02965	COG0316	Belongs to the HesB IscA family
SB85_RS02965	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SB85_RS02980	COG0428	transporter
SB85_RS02985	COG3064	Membrane
SB85_RS03055	COG0583	DNA-binding transcription factor activity
SB85_RS03085	COG0077	Prephenate dehydratase
SB85_RS03085	COG1605	Chorismate mutase
SB85_RS03090	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SB85_RS03095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SB85_RS03100	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
SB85_RS03135	COG4221	oxidoreductase activity
SB85_RS03165	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SB85_RS03200	COG4993	Dehydrogenase
SB85_RS03210	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SB85_RS03230	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SB85_RS03235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SB85_RS03250	COG0359	binds to the 23S rRNA
SB85_RS03255	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SB85_RS03265	COG0316	Belongs to the HesB IscA family
SB85_RS03290	COG0288	reversible hydration of carbon dioxide
SB85_RS03305	COG3844	kynureninase activity
SB85_RS03315	COG2925	Exonuclease
SB85_RS03360	COG2902	Dehydrogenase
SB85_RS03370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SB85_RS03375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SB85_RS03380	COG1960	acyl-CoA dehydrogenase activity
SB85_RS03385	COG2226	methyltransferase
SB85_RS03395	COG1410	methionine synthase
SB85_RS03395	COG0646	methionine synthase
SB85_RS03410	COG2755	lipolytic protein G-D-S-L family
SB85_RS03410	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SB85_RS03420	COG2900	Belongs to the SlyX family
SB85_RS03435	COG0386	Belongs to the glutathione peroxidase family
SB85_RS03445	COG1725	Transcriptional regulator
SB85_RS03450	COG1131	(ABC) transporter
SB85_RS03470	COG0697	spore germination
SB85_RS03475	COG0436	Aminotransferase
SB85_RS03495	COG1253	flavin adenine dinucleotide binding
SB85_RS03510	COG2850	peptidyl-arginine hydroxylation
SB85_RS03560	COG1132	(ABC) transporter
SB85_RS03575	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
SB85_RS03580	COG0484	heat shock protein binding
SB85_RS03585	COG0443	Heat shock 70 kDa protein
SB85_RS03590	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SB85_RS03595	COG1420	regulation of RNA biosynthetic process
SB85_RS03600	COG0497	DNA recombination
SB85_RS03605	COG0735	belongs to the Fur family
SB85_RS03610	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SB85_RS03625	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SB85_RS03645	COG3706	GGDEF domain
SB85_RS03680	COG0583	DNA-binding transcription factor activity
SB85_RS03685	COG2885	chlorophyll binding
SB85_RS03685	COG3047	cAMP biosynthetic process
SB85_RS03695	COG0415	Belongs to the DNA photolyase family
SB85_RS03705	COG0305	Participates in initiation and elongation during chromosome replication
SB85_RS03725	COG1960	acyl-CoA dehydrogenase activity
SB85_RS03740	COG0084	hydrolase, TatD family'
SB85_RS03745	COG3706	GGDEF domain
SB85_RS03745	COG2203	Gaf domain
SB85_RS03745	COG5001	Diguanylate cyclase
SB85_RS03745	COG4251	negative regulation of phosphorylation
SB85_RS03750	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SB85_RS03790	COG0625	glutathione transferase activity
SB85_RS03800	COG1595	DNA-templated transcription, initiation
SB85_RS03805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SB85_RS03835	COG0386	Belongs to the glutathione peroxidase family
SB85_RS03840	COG0339	signal peptide processing
SB85_RS03900	COG1472	Belongs to the glycosyl hydrolase 3 family
SB85_RS03910	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SB85_RS03925	COG0488	(ABC) transporter
SB85_RS03930	COG0513	Belongs to the DEAD box helicase family
SB85_RS03945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SB85_RS03965	COG0625	glutathione transferase activity
SB85_RS03975	COG4681	YaeQ
SB85_RS03980	COG2081	HI0933 family
SB85_RS04000	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS04025	COG0802	atpase or kinase
SB85_RS04030	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SB85_RS04030	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SB85_RS04035	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SB85_RS04040	COG1570	exodeoxyribonuclease VII activity
SB85_RS04050	COG3040	lipid binding
SB85_RS04070	COG1846	Transcriptional regulator
SB85_RS04090	COG1404	Belongs to the peptidase S8 family
SB85_RS04095	COG1404	Belongs to the peptidase S8 family
SB85_RS04110	COG2815	serine threonine protein kinase
SB85_RS04110	COG0515	serine threonine protein kinase
SB85_RS04120	COG2197	response regulator
SB85_RS04125	COG1960	acyl-CoA dehydrogenase activity
SB85_RS04170	COG0438	transferase activity, transferring glycosyl groups
SB85_RS04175	COG0438	transferase activity, transferring glycosyl groups
SB85_RS04220	COG0072	phenylalanine-tRNA ligase activity
SB85_RS04220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SB85_RS04225	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SB85_RS04230	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SB85_RS04240	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SB85_RS04270	COG1082	Xylose isomerase domain protein TIM barrel
SB85_RS04280	COG0366	Alpha amylase catalytic
SB85_RS04380	COG3505	Type IV secretory pathway VirD4
SB85_RS04400	COG4969	Belongs to the N-Me-Phe pilin family
SB85_RS04445	COG1611	Belongs to the LOG family
SB85_RS04460	COG2095	MarC family integral membrane protein
SB85_RS04465	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS04470	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SB85_RS04510	COG2969	positive regulation of protein catabolic process
SB85_RS04515	COG0625	glutathione transferase activity
SB85_RS04520	COG2857	Cytochrome c1
SB85_RS04530	COG0723	plastoquinol--plastocyanin reductase activity
SB85_RS04585	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SB85_RS04595	COG4535	Mg2 and Co2 transporter CorC
SB85_RS04610	COG1012	belongs to the aldehyde dehydrogenase family
SB85_RS04615	COG1177	transmembrane transport
SB85_RS04620	COG1176	ABC-type spermidine putrescine transport system, permease component I
SB85_RS04625	COG3842	ATPase activity
SB85_RS04665	COG0174	glutamine synthetase
SB85_RS04670	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SB85_RS04675	COG0174	glutamine synthetase
SB85_RS04680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SB85_RS04690	COG0477	Major facilitator Superfamily
SB85_RS04700	COG0243	molybdopterin cofactor binding
SB85_RS04705	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SB85_RS04725	COG1012	belongs to the aldehyde dehydrogenase family
SB85_RS04730	COG1396	sequence-specific DNA binding
SB85_RS04730	COG1917	Cupin 2, conserved barrel domain protein
SB85_RS04735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SB85_RS04740	COG0686	Belongs to the AlaDH PNT family
SB85_RS04755	COG2733	membrane
SB85_RS04760	COG3850	Histidine kinase
SB85_RS04760	COG4999	Histidine kinase
SB85_RS04760	COG2205	protein histidine kinase activity
SB85_RS04760	COG3437	response regulator, receiver
SB85_RS04770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SB85_RS04770	COG0116	Belongs to the methyltransferase superfamily
SB85_RS04775	COG0488	(ABC) transporter
SB85_RS04820	COG1024	Enoyl-CoA hydratase
SB85_RS04830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SB85_RS04840	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SB85_RS04845	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SB85_RS04855	COG0581	inorganic phosphate transmembrane transporter activity
SB85_RS04865	COG0704	Plays a role in the regulation of phosphate uptake
SB85_RS04885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SB85_RS04905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SB85_RS04915	COG0557	exoribonuclease II activity
SB85_RS04950	COG2814	Major facilitator Superfamily
SB85_RS04955	COG1566	PFAM secretion protein HlyD family protein
SB85_RS04965	COG1846	Transcriptional regulator
SB85_RS05000	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SB85_RS05005	COG0235	Class ii aldolase
SB85_RS05010	COG1070	Carbohydrate kinase
SB85_RS05055	COG0367	asparagine synthase
SB85_RS05070	COG1393	Belongs to the ArsC family
SB85_RS05090	COG0024	Methionine aminopeptidase
SB85_RS05125	COG0052	Belongs to the universal ribosomal protein uS2 family
SB85_RS05140	COG0528	UMP kinase activity
SB85_RS05150	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SB85_RS05155	COG0575	Belongs to the CDS family
SB85_RS05160	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SB85_RS05165	COG0750	zinc metalloprotease
SB85_RS05170	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SB85_RS05175	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SB85_RS05180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SB85_RS05185	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SB85_RS05220	COG1981	membrane
SB85_RS05305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SB85_RS05315	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SB85_RS05320	COG3291	Pkd domain containing protein
SB85_RS05325	COG1538	Outer membrane efflux protein
SB85_RS05335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SB85_RS05345	COG0642	Histidine kinase
SB85_RS05350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SB85_RS05355	COG0405	Gamma-glutamyltransferase
SB85_RS05360	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SB85_RS05385	COG0742	ribosomal rna small subunit methyltransferase
SB85_RS05390	COG0326	Molecular chaperone. Has ATPase activity
SB85_RS05415	COG3507	Belongs to the glycosyl hydrolase 43 family
SB85_RS05445	COG0531	amino acid
SB85_RS05460	COG0006	proline dipeptidase activity
SB85_RS05470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SB85_RS05485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SB85_RS05490	COG3938	Belongs to the proline racemase family
SB85_RS05500	COG0552	protein localization to endoplasmic reticulum
SB85_RS05505	COG1194	a g-specific adenine glycosylase
SB85_RS05550	COG0835	chemotaxis
SB85_RS05555	COG0840	transmembrane signaling receptor activity
SB85_RS05560	COG0840	transmembrane signaling receptor activity
SB85_RS05565	COG1201	RNA secondary structure unwinding
SB85_RS05575	COG3300	MHYT domain
SB85_RS05575	COG5001	Diguanylate cyclase
SB85_RS05580	COG1185	polyribonucleotide nucleotidyltransferase activity
SB85_RS05595	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SB85_RS05605	COG0195	Participates in both transcription termination and antitermination
SB85_RS05620	COG1007	ATP synthesis coupled electron transport
SB85_RS05655	COG1034	ATP synthesis coupled electron transport
SB85_RS05660	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SB85_RS05665	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
SB85_RS05670	COG0649	NAD binding
SB85_RS05675	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SB85_RS05685	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SB85_RS05705	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS05745	COG0159	tryptophan synthase activity
SB85_RS05755	COG0133	tryptophan synthase activity
SB85_RS05765	COG0135	phosphoribosylanthranilate isomerase activity
SB85_RS05770	COG0101	tRNA pseudouridine synthase activity
SB85_RS05785	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SB85_RS05800	COG2890	protein-(glutamine-N5) methyltransferase activity
SB85_RS05815	COG0741	lytic transglycosylase activity
SB85_RS05820	COG0433	COG0433 Predicted ATPase
SB85_RS05830	COG0494	nUDIX hydrolase
SB85_RS05845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SB85_RS05885	COG0717	Belongs to the dCTP deaminase family
SB85_RS05890	COG0489	protein tyrosine kinase activity
SB85_RS05910	COG3590	peptidase
SB85_RS05940	COG2311	Membrane
SB85_RS05950	COG0791	NLP P60 protein
SB85_RS05955	COG0791	NLP P60 protein
SB85_RS05960	COG2226	methyltransferase
SB85_RS05970	COG1607	acyl-coa hydrolase
SB85_RS05980	COG1301	dicarboxylic acid transport
SB85_RS05985	COG1785	Belongs to the alkaline phosphatase family
SB85_RS05995	COG0037	tRNA processing
SB85_RS06000	COG1722	exodeoxyribonuclease VII activity
SB85_RS06005	COG0142	geranyltranstransferase activity
SB85_RS06010	COG4104	PAAR repeat-containing protein
SB85_RS06035	COG0312	modulator of DNA gyrase
SB85_RS06045	COG0312	modulator of DNA gyrase
SB85_RS06065	COG2968	Membrane
SB85_RS06080	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SB85_RS06095	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SB85_RS06120	COG3118	belongs to the thioredoxin family
SB85_RS06140	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SB85_RS06150	COG2040	homocysteine
SB85_RS06160	COG0346	lactoylglutathione lyase activity
SB85_RS06170	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SB85_RS06170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SB85_RS06185	COG2878	Part of a membrane complex involved in electron transport
SB85_RS06200	COG1595	DNA-templated transcription, initiation
SB85_RS06225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SB85_RS06245	COG0251	oxidation-reduction process
SB85_RS06255	COG0392	lysyltransferase activity
SB85_RS06295	COG2814	Major facilitator Superfamily
SB85_RS06300	COG1902	pentaerythritol trinitrate reductase activity
SB85_RS06305	COG2824	Alkylphosphonate utilization operon protein PhnA
SB85_RS06315	COG1047	Peptidyl-prolyl cis-trans
SB85_RS06320	COG1077	Cell shape determining protein MreB Mrl
SB85_RS06350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SB85_RS06360	COG1451	nucleotide metabolic process
SB85_RS06365	COG1187	pseudouridine synthase activity
SB85_RS06375	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SB85_RS06380	COG4771	TonB-dependent receptor
SB85_RS06415	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SB85_RS06415	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SB85_RS06415	COG1703	isobutyryl-CoA mutase activity
SB85_RS06460	COG1960	acyl-CoA dehydrogenase activity
SB85_RS06465	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SB85_RS06465	COG1793	dna ligase
SB85_RS06470	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SB85_RS06470	COG1793	dna ligase
SB85_RS06475	COG1201	RNA secondary structure unwinding
SB85_RS06490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SB85_RS06495	COG1278	Cold shock
SB85_RS06500	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SB85_RS06505	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SB85_RS06510	COG1472	Belongs to the glycosyl hydrolase 3 family
SB85_RS06515	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SB85_RS06520	COG2954	triphosphatase activity
SB85_RS06540	COG1381	Involved in DNA repair and RecF pathway recombination
SB85_RS06545	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SB85_RS06560	COG0681	Belongs to the peptidase S26 family
SB85_RS06565	COG0481	GTPase activity
SB85_RS06570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SB85_RS06585	COG1250	3-hydroxyacyl-CoA dehydrogenase
SB85_RS06585	COG1024	Enoyl-CoA hydratase
SB85_RS06600	COG2855	membrane
SB85_RS06615	COG3867	Arabinogalactan endo-beta-1,4-galactanase
SB85_RS06630	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SB85_RS06645	COG0542	response to heat
SB85_RS06660	COG0534	Mate efflux family protein
SB85_RS06665	COG0335	large ribosomal subunit rRNA binding
SB85_RS06675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SB85_RS06690	COG2070	2-Nitropropane dioxygenase
SB85_RS06705	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SB85_RS06710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SB85_RS06740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SB85_RS06745	COG0475	glutathione-regulated potassium exporter activity
SB85_RS06755	COG0625	glutathione transferase activity
SB85_RS06765	COG1172	Belongs to the binding-protein-dependent transport system permease family
SB85_RS06770	COG1172	Belongs to the binding-protein-dependent transport system permease family
SB85_RS06775	COG1129	ABC transporter
SB85_RS06780	COG1879	ABC-type sugar transport system periplasmic component
SB85_RS06785	COG1012	belongs to the aldehyde dehydrogenase family
SB85_RS06800	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS06805	COG0129	dihydroxy-acid dehydratase activity
SB85_RS06810	COG1595	DNA-templated transcription, initiation
SB85_RS06855	COG0740	serine-type endopeptidase activity
SB85_RS06860	COG1595	DNA-templated transcription, initiation
SB85_RS06865	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
SB85_RS06870	COG1845	cytochrome c oxidase, subunit III
SB85_RS06875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SB85_RS06900	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SB85_RS06915	COG0196	riboflavin kinase activity
SB85_RS06920	COG0728	peptidoglycan biosynthetic process
SB85_RS06930	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SB85_RS06935	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SB85_RS06940	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SB85_RS06945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SB85_RS06950	COG0824	Thioesterase
SB85_RS06960	COG1024	Enoyl-CoA hydratase
SB85_RS06965	COG1946	Acyl-CoA thioesterase
SB85_RS06980	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
SB85_RS06995	COG0840	transmembrane signaling receptor activity
SB85_RS07015	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SB85_RS07020	COG4638	Rieske (2fe-2S)
SB85_RS07045	COG1073	alpha beta
SB85_RS07090	COG4585	Histidine kinase
SB85_RS07105	COG2894	cell division
SB85_RS07110	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SB85_RS07120	COG2205	protein histidine kinase activity
SB85_RS07125	COG0745	RESPONSE REGULATOR receiver
SB85_RS07135	COG2194	sulfuric ester hydrolase activity
SB85_RS07155	COG2814	Major facilitator Superfamily
SB85_RS07160	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SB85_RS07160	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SB85_RS07165	COG0753	catalase activity
SB85_RS07170	COG1063	alcohol dehydrogenase
SB85_RS07230	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SB85_RS07245	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SB85_RS07280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SB85_RS07290	COG0330	HflC and HflK could
SB85_RS07295	COG0330	HflC and HflK could
SB85_RS07300	COG0604	alcohol dehydrogenase
SB85_RS07320	COG0678	peroxiredoxin activity
SB85_RS07335	COG4953	penicillin-binding protein 1C
SB85_RS07340	COG4191	Histidine kinase
SB85_RS07355	COG0577	efflux transmembrane transporter activity
SB85_RS07355	COG1136	(ABC) transporter
SB85_RS07380	COG2373	Large extracellular alpha-helical protein
SB85_RS07445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SB85_RS07470	COG2161	toxin-antitoxin pair type II binding
SB85_RS07475	COG4115	mRNA cleavage
SB85_RS07495	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SB85_RS07500	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SB85_RS07505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SB85_RS07520	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS07525	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SB85_RS07535	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SB85_RS07540	COG1399	metal-binding, possibly nucleic acid-binding protein
SB85_RS07565	COG0714	Associated with various cellular activities
SB85_RS07585	COG0537	adenosine 5'-monophosphoramidase activity
SB85_RS07600	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SB85_RS07610	COG0314	molybdopterin synthase activity
SB85_RS07615	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SB85_RS07620	COG0315	cyclic pyranopterin monophosphate synthase activity
SB85_RS07630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SB85_RS07635	COG1234	tRNA 3'-trailer cleavage
SB85_RS07640	COG3642	lipopolysaccharide core region biosynthetic process
SB85_RS07645	COG0859	PFAM glycosyl transferase family 9
SB85_RS07665	COG0631	protein serine/threonine phosphatase activity
SB85_RS07675	COG0328	RNA-DNA hybrid ribonuclease activity
SB85_RS07685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SB85_RS07695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SB85_RS07735	COG0544	peptidyl-prolyl cis-trans isomerase activity
SB85_RS07775	COG0473	3-isopropylmalate dehydrogenase activity
SB85_RS07790	COG4783	chaperone-mediated protein folding
SB85_RS07795	COG0745	RESPONSE REGULATOR receiver
SB85_RS07805	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SB85_RS07810	COG0248	Ppx GppA phosphatase
SB85_RS07815	COG0438	transferase activity, transferring glycosyl groups
SB85_RS07825	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SB85_RS07835	COG3291	Pkd domain containing protein
SB85_RS07840	COG2833	Protein of unknown function (DUF455)
SB85_RS07865	COG0285	dihydrofolate synthase activity
SB85_RS07870	COG0588	phosphoglycerate mutase activity
SB85_RS07890	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SB85_RS07895	COG4208	sulfate ABC transporter
SB85_RS07900	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SB85_RS07935	COG0583	DNA-binding transcription factor activity
SB85_RS07950	COG0667	Aldo Keto reductase
SB85_RS07955	COG0604	alcohol dehydrogenase
SB85_RS07960	COG0446	pyridine nucleotide-disulphide oxidoreductase
SB85_RS07960	COG1902	pentaerythritol trinitrate reductase activity
SB85_RS07980	COG0584	glycerophosphoryl diester phosphodiesterase
SB85_RS08000	COG0625	glutathione transferase activity
SB85_RS08020	COG0625	glutathione transferase activity
SB85_RS08040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SB85_RS08045	COG1217	gtp-binding protein TYPA
SB85_RS08065	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SB85_RS08085	COG0203	ribosomal protein L17
SB85_RS08095	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SB85_RS08105	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SB85_RS08110	COG0201	protein transport
SB85_RS08120	COG1841	ribosomal large subunit assembly
SB85_RS08130	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SB85_RS08145	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SB85_RS08150	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SB85_RS08155	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SB85_RS08165	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SB85_RS08170	COG0255	Belongs to the universal ribosomal protein uL29 family
SB85_RS08180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SB85_RS08190	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SB85_RS08195	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SB85_RS08200	COG0089	rRNA binding
SB85_RS08205	COG0088	Forms part of the polypeptide exit tunnel
SB85_RS08215	COG0051	transcription antitermination factor activity, RNA binding
SB85_RS08220	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SB85_RS08225	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SB85_RS08230	COG0049	tRNA binding
SB85_RS08240	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SB85_RS08250	COG0222	ribosome binding
SB85_RS08255	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SB85_RS08270	COG0250	Participates in transcription elongation, termination and antitermination
SB85_RS08285	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SB85_RS08305	COG0012	GTP binding
SB85_RS08310	COG0193	aminoacyl-tRNA hydrolase activity
SB85_RS08320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SB85_RS08330	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SB85_RS08345	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SB85_RS08350	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SB85_RS08370	COG0521	Mo-molybdopterin cofactor biosynthetic process
SB85_RS08385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SB85_RS08390	COG1295	ribonuclease BN
SB85_RS08410	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SB85_RS08415	COG1404	Belongs to the peptidase S8 family
SB85_RS08420	COG1404	Belongs to the peptidase S8 family
SB85_RS08425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SB85_RS08485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SB85_RS08485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SB85_RS08505	COG0583	DNA-binding transcription factor activity
SB85_RS08530	COG2890	protein-(glutamine-N5) methyltransferase activity
SB85_RS08540	COG3634	alkyl hydroperoxide reductase activity
SB85_RS08545	COG0583	DNA-binding transcription factor activity
SB85_RS08550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SB85_RS08555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SB85_RS08575	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SB85_RS08590	COG5002	protein histidine kinase activity
SB85_RS08590	COG2205	protein histidine kinase activity
SB85_RS08590	COG0784	Response regulator, receiver
SB85_RS08615	COG0697	spore germination
SB85_RS08670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SB85_RS08675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SB85_RS08685	COG2096	Adenosyltransferase
SB85_RS08705	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SB85_RS08715	COG2967	ApaG domain
SB85_RS08720	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SB85_RS08750	COG1704	LemA family
SB85_RS08755	COG0861	Integral membrane protein TerC family
SB85_RS08760	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SB85_RS08770	COG0642	Histidine kinase
SB85_RS08785	COG4181	ATPase activity
SB85_RS08790	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
SB85_RS08805	COG4771	TonB-dependent receptor
SB85_RS08815	COG0667	Aldo Keto reductase
SB85_RS08820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SB85_RS08835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SB85_RS08840	COG4106	trans-aconitate 2-methyltransferase activity
SB85_RS08880	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SB85_RS08960	COG0840	transmembrane signaling receptor activity
SB85_RS08975	COG0366	Alpha amylase catalytic
SB85_RS08980	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SB85_RS08990	COG0494	nUDIX hydrolase
SB85_RS09005	COG0739	heme binding
SB85_RS09020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SB85_RS09030	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SB85_RS09035	COG1181	Belongs to the D-alanine--D-alanine ligase family
SB85_RS09040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SB85_RS09045	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SB85_RS09060	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SB85_RS09075	COG3116	cell division
SB85_RS09080	COG0275	rRNA processing
SB85_RS09120	COG1988	membrane-bound metal-dependent
SB85_RS09125	COG0277	FAD linked oxidase domain protein
SB85_RS09130	COG0745	RESPONSE REGULATOR receiver
SB85_RS09135	COG2205	protein histidine kinase activity
SB85_RS09145	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SB85_RS09150	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SB85_RS09170	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SB85_RS09175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SB85_RS09180	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SB85_RS09195	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SB85_RS09195	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SB85_RS09205	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SB85_RS09240	COG0242	peptide deformylase activity
SB85_RS09245	COG0457	Tetratricopeptide repeat
SB85_RS09250	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
SB85_RS09255	COG1215	transferase activity, transferring glycosyl groups
SB85_RS09260	COG1215	transferase activity, transferring glycosyl groups
SB85_RS09275	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SB85_RS09325	COG2188	Transcriptional regulator
SB85_RS09335	COG1450	Type ii and iii secretion system protein
SB85_RS09350	COG3166	PFAM Fimbrial assembly family protein
SB85_RS09360	COG4795	General secretion pathway protein
SB85_RS09365	COG2165	general secretion pathway protein
SB85_RS09370	COG4970	Tfp pilus assembly protein FimT
SB85_RS09375	COG2165	general secretion pathway protein
SB85_RS09380	COG1459	type II secretion system
SB85_RS09385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SB85_RS09390	COG1404	Belongs to the peptidase S8 family
SB85_RS09395	COG5295	Hep Hag repeat protein
SB85_RS09400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SB85_RS09400	COG0047	phosphoribosylformylglycinamidine synthase activity
SB85_RS09405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SB85_RS09415	COG4974	Belongs to the 'phage' integrase family
SB85_RS09440	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SB85_RS09460	COG0525	valine-tRNA ligase activity
SB85_RS09485	COG1183	phosphatidylcholine synthase activity
SB85_RS09495	COG0442	prolyl-tRNA aminoacylation
SB85_RS09510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SB85_RS09515	COG1127	ABC transporter
SB85_RS09520	COG3218	ABC-type transport auxiliary lipoprotein component
SB85_RS09520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SB85_RS09555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SB85_RS09585	COG2086	electron transfer activity
SB85_RS09625	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SB85_RS09660	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SB85_RS09680	COG0626	cystathionine gamma-synthase activity
SB85_RS09710	COG0625	glutathione transferase activity
SB85_RS09720	COG0513	Belongs to the DEAD box helicase family
SB85_RS09725	COG0720	synthase
SB85_RS09735	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SB85_RS09740	COG1956	GAF domain-containing protein
SB85_RS09750	COG4206	TonB-dependent receptor
SB85_RS09755	COG0546	phosphoglycolate phosphatase activity
SB85_RS09765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SB85_RS09780	COG0339	signal peptide processing
SB85_RS09785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SB85_RS09795	COG2217	Heavy metal translocating P-type atpase
SB85_RS09810	COG2132	Multicopper oxidase
SB85_RS09830	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SB85_RS09840	COG1136	(ABC) transporter
SB85_RS09850	COG0577	efflux transmembrane transporter activity
SB85_RS09855	COG0577	efflux transmembrane transporter activity
SB85_RS09865	COG0577	efflux transmembrane transporter activity
SB85_RS09865	COG1136	(ABC) transporter
SB85_RS09875	COG0577	efflux transmembrane transporter activity
SB85_RS09880	COG0577	efflux transmembrane transporter activity
SB85_RS09880	COG1136	(ABC) transporter
SB85_RS09885	COG1136	(ABC) transporter
SB85_RS09885	COG0577	efflux transmembrane transporter activity
SB85_RS09895	COG0577	efflux transmembrane transporter activity
SB85_RS09905	COG4191	Histidine kinase
SB85_RS09915	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SB85_RS09930	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SB85_RS09935	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SB85_RS09945	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SB85_RS09955	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SB85_RS09965	COG0356	it plays a direct role in the translocation of protons across the membrane
SB85_RS09985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SB85_RS10030	COG0697	spore germination
SB85_RS10065	COG0657	acetylesterase activity
SB85_RS10090	COG3485	protocatechuate 3,4-dioxygenase
SB85_RS10115	COG1187	pseudouridine synthase activity
SB85_RS10160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SB85_RS10220	COG0842	Transport permease protein
SB85_RS10225	COG1131	(ABC) transporter
SB85_RS10240	COG0025	NhaP-type Na H and K H
SB85_RS10255	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
SB85_RS10260	COG1573	uracil-dna glycosylase
SB85_RS10270	COG3384	dioxygenase
SB85_RS10275	COG0583	DNA-binding transcription factor activity
SB85_RS10290	COG0667	Aldo Keto reductase
SB85_RS10300	COG0667	Aldo Keto reductase
SB85_RS10315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SB85_RS10320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SB85_RS10380	COG3275	phosphorelay sensor kinase activity
SB85_RS10390	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SB85_RS10400	COG0531	amino acid
SB85_RS10420	COG5297	Belongs to the glycosyl hydrolase family 6
SB85_RS10420	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SB85_RS10425	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SB85_RS10425	COG5297	Belongs to the glycosyl hydrolase family 6
SB85_RS10430	COG0612	Peptidase, M16
SB85_RS10450	COG0741	lytic transglycosylase activity
SB85_RS10470	COG2207	Transcriptional regulator
SB85_RS10480	COG0598	Magnesium transport protein CorA
SB85_RS10485	COG1113	amino acid transport
SB85_RS10495	COG0697	spore germination
SB85_RS10520	COG0583	DNA-binding transcription factor activity
SB85_RS10540	COG2409	Drug exporters of the RND superfamily
SB85_RS10550	COG5520	Belongs to the glycosyl hydrolase 30 family
SB85_RS10560	COG3550	peptidyl-serine autophosphorylation
SB85_RS10690	COG2353	YceI-like domain
SB85_RS10695	COG0778	Nitroreductase
SB85_RS10725	COG0584	glycerophosphoryl diester phosphodiesterase
SB85_RS10740	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SB85_RS10745	COG0477	Major facilitator Superfamily
SB85_RS10760	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SB85_RS10765	COG2827	Endonuclease containing a URI domain
SB85_RS10770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SB85_RS10790	COG0459	protein refolding
SB85_RS10795	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SB85_RS10800	COG2356	endonuclease I
SB85_RS10805	COG1324	tolerance protein
SB85_RS10810	COG4232	protein-disulfide reductase activity
SB85_RS10815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SB85_RS10825	COG3291	Pkd domain containing protein
SB85_RS10825	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SB85_RS10830	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SB85_RS10835	COG0511	ligase activity, forming carbon-carbon bonds
SB85_RS10845	COG0439	Biotin carboxylase
SB85_RS10860	COG2264	protein methyltransferase activity
SB85_RS10875	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
SB85_RS10880	COG4589	Belongs to the CDS family
SB85_RS10905	COG2453	phosphatase
SB85_RS10905	COG0671	phosphoesterase, PA-phosphatase related
SB85_RS10910	COG2267	carboxylic ester hydrolase activity
SB85_RS10915	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SB85_RS10920	COG0138	bifunctional purine biosynthesis protein purh
SB85_RS10930	COG0151	Belongs to the GarS family
SB85_RS10940	COG1289	transmembrane transporter activity
SB85_RS10945	COG2814	Major facilitator Superfamily
SB85_RS10995	COG2816	NAD+ diphosphatase activity
SB85_RS11000	COG0316	Belongs to the HesB IscA family
SB85_RS11040	COG1051	belongs to the nudix hydrolase family
SB85_RS11055	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SB85_RS11080	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SB85_RS11085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SB85_RS11090	COG0730	response to heat
SB85_RS11095	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SB85_RS11095	COG4124	Belongs to the glycosyl hydrolase 26 family
SB85_RS11105	COG0134	indole-3-glycerol-phosphate synthase activity
SB85_RS11110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SB85_RS11140	COG1597	lipid kinase activity
SB85_RS11150	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SB85_RS11155	COG0484	heat shock protein binding
SB85_RS11195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SB85_RS11195	COG2111	Na H antiporter
SB85_RS11200	COG1006	Multisubunit Na H antiporter MnhC subunit
SB85_RS11205	COG0651	ATP synthesis coupled electron transport
SB85_RS11210	COG1863	multisubunit Na H antiporter MnhE subunit
SB85_RS11215	COG2212	antiporter activity
SB85_RS11220	COG1320	monovalent cation:proton antiporter activity
SB85_RS11225	COG0530	calcium, potassium:sodium antiporter activity
SB85_RS11230	COG0753	catalase activity
SB85_RS11250	COG2197	response regulator
SB85_RS11255	COG4585	Histidine kinase
SB85_RS11265	COG1131	(ABC) transporter
SB85_RS11270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SB85_RS11280	COG1136	(ABC) transporter
SB85_RS11285	COG0577	efflux transmembrane transporter activity
SB85_RS11305	COG0697	spore germination
SB85_RS11325	COG0180	Tryptophanyl-tRNA synthetase
SB85_RS11335	COG3237	CsbD-like
SB85_RS11350	COG0010	Belongs to the arginase family
SB85_RS11370	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SB85_RS11415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SB85_RS11450	COG2205	protein histidine kinase activity
SB85_RS11455	COG0745	RESPONSE REGULATOR receiver
SB85_RS11470	COG2084	Dehydrogenase
SB85_RS11475	COG1902	pentaerythritol trinitrate reductase activity
SB85_RS11500	COG1404	Belongs to the peptidase S8 family
SB85_RS11520	COG1404	Belongs to the peptidase S8 family
SB85_RS11530	COG2814	Major facilitator Superfamily
SB85_RS11535	COG0583	DNA-binding transcription factor activity
SB85_RS11545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SB85_RS11555	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SB85_RS11560	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SB85_RS11590	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SB85_RS11595	COG1764	response to oxidative stress
SB85_RS11600	COG1846	Transcriptional regulator
SB85_RS11610	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
SB85_RS11620	COG0697	spore germination
SB85_RS11625	COG0523	cobalamin synthesis protein
SB85_RS11655	COG1960	acyl-CoA dehydrogenase activity
SB85_RS11660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SB85_RS11700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SB85_RS11700	COG1042	CoA-binding domain protein
SB85_RS11700	COG0045	succinate-CoA ligase (ADP-forming) activity
SB85_RS11710	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SB85_RS11715	COG3387	PFAM Glycoside hydrolase 15-related
SB85_RS11720	COG0745	RESPONSE REGULATOR receiver
SB85_RS11735	COG1404	Belongs to the peptidase S8 family
SB85_RS11745	COG3100	YcgL domain-containing protein
SB85_RS11750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SB85_RS11760	COG0463	Glycosyl transferase, family 2
SB85_RS11775	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS11800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SB85_RS11815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SB85_RS11830	COG2094	Belongs to the DNA glycosylase MPG family
SB85_RS11840	COG2911	Protein conserved in bacteria
SB85_RS11845	COG0729	surface antigen
SB85_RS11860	COG3132	Protein of unknown function, DUF480
SB85_RS11865	COG3210	domain, Protein
SB85_RS11865	COG3210	domain, Protein
SB85_RS11865	COG3210	domain, Protein
SB85_RS11880	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SB85_RS11885	COG0284	orotidine-5'-phosphate decarboxylase activity
SB85_RS11905	COG1609	Transcriptional regulator
SB85_RS11920	COG2937	Belongs to the GPAT DAPAT family
SB85_RS11975	COG0840	transmembrane signaling receptor activity
SB85_RS11985	COG3046	protein related to deoxyribodipyrimidine photolyase
SB85_RS12005	COG0037	tRNA processing
SB85_RS12020	COG0840	transmembrane signaling receptor activity
SB85_RS12030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SB85_RS12050	COG0805	protein transport
SB85_RS12060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SB85_RS12060	COG0519	Catalyzes the synthesis of GMP from XMP
SB85_RS12065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SB85_RS12080	COG0457	Tetratricopeptide repeat
SB85_RS12090	COG0210	DNA helicase
SB85_RS12105	COG2155	Conserved Protein
SB85_RS12110	COG3265	gluconokinase activity
SB85_RS12120	COG1294	oxidase, subunit
SB85_RS12125	COG1271	oxidase subunit
SB85_RS12145	COG0408	coproporphyrinogen oxidase activity
SB85_RS12165	COG0589	response to stress
SB85_RS12185	COG3568	Endonuclease Exonuclease Phosphatase
SB85_RS12195	COG0392	lysyltransferase activity
SB85_RS12210	COG0210	DNA helicase
SB85_RS12215	COG0583	DNA-binding transcription factor activity
SB85_RS12220	COG0477	Major facilitator Superfamily
SB85_RS12230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SB85_RS12235	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SB85_RS12240	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SB85_RS12280	COG0463	Glycosyl transferase, family 2
SB85_RS12305	COG1192	Involved in chromosome partitioning
SB85_RS12310	COG0357	Ribosomal RNA small subunit methyltransferase G
SB85_RS12315	COG2091	lysine biosynthetic process via aminoadipic acid
SB85_RS12340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SB85_RS12355	COG1011	Hydrolase
SB85_RS12360	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SB85_RS12385	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SB85_RS12395	COG1024	Enoyl-CoA hydratase
SB85_RS12400	COG1024	Enoyl-CoA hydratase
SB85_RS12405	COG1960	acyl-CoA dehydrogenase activity
SB85_RS12430	COG0457	Tetratricopeptide repeat
SB85_RS12435	COG0784	Response regulator, receiver
SB85_RS12435	COG2198	Histidine kinase
SB85_RS12435	COG2205	protein histidine kinase activity
SB85_RS12440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SB85_RS12445	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
SB85_RS12450	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SB85_RS12465	COG1119	ATPase activity
SB85_RS12470	COG1733	regulation of RNA biosynthetic process
SB85_RS12490	COG0210	DNA helicase
SB85_RS12495	COG1111	helicase
SB85_RS12495	COG1205	dead DEAH box helicase
SB85_RS12515	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SB85_RS12540	COG0594	ribonuclease P activity
SB85_RS12555	COG0592	DNA-directed DNA polymerase activity
SB85_RS12565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SB85_RS12570	COG0187	DNA topoisomerase II activity
SB85_RS12575	COG1266	CAAX protease self-immunity
SB85_RS12580	COG0501	Belongs to the peptidase M48B family
SB85_RS12625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SB85_RS12645	COG0655	NAD(P)H dehydrogenase (quinone) activity
SB85_RS12670	COG4772	TonB-dependent receptor
SB85_RS12675	COG3284	Transcriptional regulator
SB85_RS12680	COG1012	belongs to the aldehyde dehydrogenase family
SB85_RS12725	COG2186	Transcriptional regulator
SB85_RS12740	COG4585	Histidine kinase
SB85_RS12745	COG2197	response regulator
SB85_RS12815	COG2963	transposase activity
SB85_RS12820	COG2801	Transposase and inactivated derivatives
SB85_RS12890	COG4771	TonB-dependent receptor
SB85_RS12895	COG4774	siderophore transport
SB85_RS12895	COG1629	transport
SB85_RS12925	COG0657	acetylesterase activity
SB85_RS12925	COG2755	lipolytic protein G-D-S-L family
SB85_RS12935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SB85_RS12950	COG1609	Transcriptional regulator
SB85_RS12960	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
SB85_RS12965	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS12995	COG1522	sequence-specific DNA binding
SB85_RS13015	COG1752	Esterase of the alpha-beta hydrolase superfamily
SB85_RS13035	COG0840	transmembrane signaling receptor activity
SB85_RS13050	COG0861	Integral membrane protein TerC family
SB85_RS13055	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SB85_RS13085	COG0531	amino acid
SB85_RS13090	COG4566	intracellular signal transduction
SB85_RS13095	COG4191	Histidine kinase
SB85_RS13100	COG1285	pathogenesis
SB85_RS13110	COG1322	Protein conserved in bacteria
SB85_RS13115	COG0386	Belongs to the glutathione peroxidase family
SB85_RS13120	COG2853	Lipoprotein
SB85_RS13135	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SB85_RS13140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SB85_RS13145	COG1127	ABC transporter
SB85_RS13180	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SB85_RS13185	COG1074	ATP-dependent DNA helicase activity
SB85_RS13190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SB85_RS13235	COG0840	transmembrane signaling receptor activity
SB85_RS13245	COG0477	Major facilitator Superfamily
SB85_RS13250	COG0302	gtp cyclohydrolase
SB85_RS13280	COG2951	lytic endotransglycosylase activity
SB85_RS13300	COG3135	benzoate transporter
SB85_RS13340	COG1803	Methylglyoxal synthase
SB85_RS13345	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SB85_RS13350	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SB85_RS13365	COG0493	'glutamate synthase
SB85_RS13370	COG0067	glutamate synthase
SB85_RS13370	COG0069	glutamate synthase activity
SB85_RS13370	COG0070	glutamate synthase
SB85_RS13395	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS13425	COG1205	dead DEAH box helicase
SB85_RS13425	COG1111	helicase
SB85_RS13480	COG2814	Major facilitator Superfamily
SB85_RS13530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SB85_RS13535	COG1192	Involved in chromosome partitioning
SB85_RS13540	COG2062	phosphohistidine phosphatase, SixA
SB85_RS13550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SB85_RS13555	COG2050	protein possibly involved in aromatic compounds catabolism
SB85_RS13580	COG1968	undecaprenyl-diphosphatase activity
SB85_RS13585	COG0174	glutamine synthetase
SB85_RS13595	COG0347	Belongs to the P(II) protein family
SB85_RS13600	COG0004	ammonium transporteR
SB85_RS13605	COG3852	Histidine kinase
SB85_RS13610	COG2204	response regulator
SB85_RS13615	COG2032	superoxide dismutase activity
SB85_RS13620	COG2032	superoxide dismutase activity
SB85_RS13635	COG0183	Belongs to the thiolase family
SB85_RS13660	COG0456	acetyltransferase
SB85_RS13675	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
SB85_RS13680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SB85_RS13690	COG3226	Transcriptional regulator
SB85_RS13700	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SB85_RS13710	COG0612	Peptidase, M16
SB85_RS13720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SB85_RS13725	COG3177	Filamentation induced by cAMP protein fic
SB85_RS13735	COG0596	Alpha beta hydrolase
SB85_RS13745	COG0727	PFAM Uncharacterised protein family (UPF0153)
SB85_RS13750	COG0318	PFAM AMP-dependent synthetase and ligase
SB85_RS13755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SB85_RS13810	COG1595	DNA-templated transcription, initiation
SB85_RS13815	COG1446	asparaginase
SB85_RS13835	COG0681	Belongs to the peptidase S26 family
SB85_RS13855	COG0583	DNA-binding transcription factor activity
SB85_RS13860	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SB85_RS13865	COG2224	Isocitrate lyase
SB85_RS13870	COG3706	GGDEF domain
SB85_RS13920	COG2319	Wd-40 repeat
SB85_RS13920	COG4249	Peptidase C14 caspase catalytic subunit p20
SB85_RS13925	COG4297	protein containing double-stranded beta helix domain
SB85_RS13930	COG0659	secondary active sulfate transmembrane transporter activity
SB85_RS13960	COG1024	Enoyl-CoA hydratase
SB85_RS13965	COG1022	Amp-dependent synthetase and ligase
SB85_RS13975	COG2814	Major facilitator Superfamily
SB85_RS14035	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SB85_RS14045	COG3485	protocatechuate 3,4-dioxygenase
SB85_RS14050	COG3485	protocatechuate 3,4-dioxygenase
SB85_RS14060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SB85_RS14065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SB85_RS14075	COG2814	Major facilitator Superfamily
SB85_RS14100	COG1187	pseudouridine synthase activity
SB85_RS14110	COG1643	Atp-dependent helicase
SB85_RS14115	COG0084	hydrolase, TatD family'
SB85_RS14130	COG2885	chlorophyll binding
SB85_RS14130	COG3047	cAMP biosynthetic process
SB85_RS14205	COG0842	Transport permease protein
SB85_RS14210	COG1131	(ABC) transporter
SB85_RS14215	COG0543	2 iron, 2 sulfur cluster binding
SB85_RS14215	COG0633	Ferredoxin
SB85_RS14225	COG1476	TRANSCRIPTIONal
SB85_RS14235	COG4555	ABC transporter
SB85_RS14260	COG0625	glutathione transferase activity
SB85_RS14345	COG1199	ATP-dependent helicase activity
SB85_RS14405	COG4615	Cyclic peptide transporter
SB85_RS14455	COG3511	phospholipase C
SB85_RS14465	COG0628	permease
SB85_RS14540	COG0754	glutathionylspermidine amidase activity
SB85_RS14560	COG0714	Associated with various cellular activities
SB85_RS14590	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SB85_RS14595	COG3420	alginic acid biosynthetic process
SB85_RS14605	COG0710	3-dehydroquinate dehydratase activity
SB85_RS14620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SB85_RS14625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SB85_RS14640	COG0657	acetylesterase activity
SB85_RS14655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SB85_RS14665	COG3023	N-Acetylmuramoyl-L-alanine amidase
SB85_RS14675	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SB85_RS14705	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SB85_RS14710	COG1040	competence protein
SB85_RS14715	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SB85_RS14755	COG0606	chelatase, subunit chli
SB85_RS14760	COG2960	long-chain fatty acid transporting porin activity
SB85_RS14785	COG1166	arginine decarboxylase activity
SB85_RS14795	COG3275	phosphorelay sensor kinase activity
SB85_RS14800	COG3279	Response regulator of the LytR AlgR family
SB85_RS14820	COG0583	DNA-binding transcription factor activity
SB85_RS14850	COG4221	oxidoreductase activity
SB85_RS14865	COG2003	Belongs to the UPF0758 family
SB85_RS14870	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SB85_RS14880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SB85_RS14890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SB85_RS14895	COG0708	Exodeoxyribonuclease III
SB85_RS14900	COG2211	Major facilitator Superfamily
SB85_RS14915	COG0739	heme binding
SB85_RS14920	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SB85_RS14950	COG1064	alcohol dehydrogenase
SB85_RS14955	COG2234	aminopeptidase activity
SB85_RS14965	COG4942	peptidase
SB85_RS14970	COG0793	Belongs to the peptidase S41A family
SB85_RS14975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SB85_RS15010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SB85_RS15020	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
SB85_RS15055	COG0840	transmembrane signaling receptor activity
SB85_RS15075	COG0358	DNA primase activity
SB85_RS15080	COG1295	ribonuclease BN
SB85_RS15100	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SB85_RS15105	COG0668	transmembrane transport
SB85_RS15110	COG2308	Evidence 4 Homologs of previously reported genes of
SB85_RS15125	COG4682	membrane
SB85_RS15130	COG2133	pyrroloquinoline quinone binding
SB85_RS15150	COG0531	amino acid
SB85_RS15160	COG1609	Transcriptional regulator
SB85_RS15185	COG1070	Carbohydrate kinase
SB85_RS15195	COG1472	Belongs to the glycosyl hydrolase 3 family
SB85_RS15205	COG3661	Belongs to the glycosyl hydrolase 67 family
SB85_RS15230	COG4948	Mandelate Racemase Muconate Lactonizing
SB85_RS15245	COG4771	TonB-dependent receptor
SB85_RS15250	COG3023	N-Acetylmuramoyl-L-alanine amidase
SB85_RS15275	COG3409	Peptidoglycan-binding domain 1 protein
SB85_RS15275	COG3501	Rhs element vgr protein
SB85_RS15310	COG5383	Protein conserved in bacteria
SB85_RS15315	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SB85_RS15320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SB85_RS15325	COG0628	permease
SB85_RS15345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SB85_RS15410	COG0708	Exodeoxyribonuclease III
SB85_RS15415	COG1418	mRNA catabolic process
SB85_RS15420	COG4807	Protein conserved in bacteria
SB85_RS15435	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SB85_RS15470	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS15475	COG0179	Fumarylacetoacetate (FAA) hydrolase
SB85_RS15480	COG4948	Mandelate Racemase Muconate Lactonizing
SB85_RS15485	COG3254	rhamnose metabolic process
SB85_RS15490	COG0738	Major facilitator superfamily
SB85_RS15495	COG1414	Transcriptional regulator
SB85_RS15555	COG0604	alcohol dehydrogenase
SB85_RS15560	COG1196	nuclear chromosome segregation
SB85_RS15560	COG3264	Mechanosensitive ion channel
SB85_RS15565	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SB85_RS15580	COG2354	Protein conserved in bacteria
SB85_RS15585	COG2354	Protein conserved in bacteria
SB85_RS15605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SB85_RS15615	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS15625	COG0513	Belongs to the DEAD box helicase family
SB85_RS15660	COG3483	tryptophan 2,3-dioxygenase activity
SB85_RS15665	COG3104	oligopeptide transport
SB85_RS15685	COG2852	Protein conserved in bacteria
SB85_RS15690	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SB85_RS15710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SB85_RS15715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SB85_RS15720	COG1473	amidohydrolase
SB85_RS15730	COG1652	LysM domain
SB85_RS15745	COG1349	DNA-binding transcription factor activity
SB85_RS15755	COG1940	carbohydrate kinase activity
SB85_RS15760	COG2222	sugar isomerase
SB85_RS15775	COG0673	inositol 2-dehydrogenase activity
SB85_RS15805	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SB85_RS15810	COG3118	belongs to the thioredoxin family
SB85_RS15820	COG2884	Cell division ATP-binding protein ftsE
SB85_RS15825	COG2177	Part of the ABC transporter FtsEX involved in
SB85_RS15830	COG2201	protein-glutamate methylesterase activity
SB85_RS15835	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SB85_RS15840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SB85_RS15845	COG2860	membrane
SB85_RS15850	COG1252	NADH dehydrogenase
SB85_RS15860	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SB85_RS15870	COG0534	Mate efflux family protein
SB85_RS15875	COG0616	signal peptide processing
SB85_RS15885	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS15900	COG0009	L-threonylcarbamoyladenylate synthase
SB85_RS15905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SB85_RS15905	COG1754	DNA topoisomerase type I activity
SB85_RS15910	COG1714	RDD family
SB85_RS15925	COG0758	DNA mediated transformation
SB85_RS15930	COG1652	LysM domain
SB85_RS15935	COG0242	peptide deformylase activity
SB85_RS15945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SB85_RS15945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SB85_RS15950	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SB85_RS15985	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SB85_RS16000	COG1490	D-aminoacyl-tRNA deacylase activity
SB85_RS16005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SB85_RS16020	COG1609	Transcriptional regulator
SB85_RS16025	COG3537	Alpha-1,2-mannosidase
SB85_RS16030	COG0366	Alpha amylase catalytic
SB85_RS16035	COG0366	Alpha amylase catalytic
SB85_RS16085	COG1191	sigma factor activity
SB85_RS16110	COG1609	Transcriptional regulator
SB85_RS16125	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SB85_RS16140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SB85_RS16145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SB85_RS16155	COG5002	protein histidine kinase activity
SB85_RS16160	COG3038	cytochrome b561
SB85_RS16165	COG1309	transcriptional regulator
SB85_RS16190	COG2271	Major facilitator Superfamily
SB85_RS16210	COG0840	transmembrane signaling receptor activity
SB85_RS16215	COG3546	catalase activity
SB85_RS16220	COG3685	Protein conserved in bacteria
SB85_RS16225	COG3685	Protein conserved in bacteria
SB85_RS16230	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS16240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SB85_RS16265	COG0028	Belongs to the TPP enzyme family
SB85_RS16270	COG4191	Histidine kinase
SB85_RS16295	COG1648	precorrin-2 dehydrogenase activity
SB85_RS16295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SB85_RS16305	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SB85_RS16305	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SB85_RS16335	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SB85_RS16345	COG0297	glycogen (starch) synthase activity
SB85_RS16355	COG2204	response regulator
SB85_RS16365	COG1335	isochorismatase
SB85_RS16385	COG0181	hydroxymethylbilane synthase activity
SB85_RS16400	COG1733	regulation of RNA biosynthetic process
SB85_RS16415	COG1505	serine-type exopeptidase activity
SB85_RS16425	COG0436	Aminotransferase
SB85_RS16435	COG2832	Protein of unknown function (DUF454)
SB85_RS16445	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SB85_RS16465	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
SB85_RS16470	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
SB85_RS16490	COG2226	methyltransferase
SB85_RS16495	COG0308	aminopeptidase N
SB85_RS16500	COG0596	Alpha beta hydrolase
SB85_RS16500	COG0508	dehydrogenase complex catalyzes the overall conversion of
SB85_RS16545	COG3284	Transcriptional regulator
SB85_RS16560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SB85_RS16565	COG1077	Cell shape determining protein MreB Mrl
SB85_RS16570	COG1792	Involved in formation and maintenance of cell shape
SB85_RS16580	COG0768	penicillin binding
SB85_RS16585	COG0772	Belongs to the SEDS family
SB85_RS16595	COG5434	Belongs to the glycosyl hydrolase 28 family
SB85_RS16600	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
SB85_RS16615	COG1012	belongs to the aldehyde dehydrogenase family
SB85_RS16620	COG2951	lytic endotransglycosylase activity
SB85_RS16630	COG1686	Belongs to the peptidase S11 family
SB85_RS16685	COG0583	DNA-binding transcription factor activity
SB85_RS16700	COG1056	cytidyltransferase-related domain
SB85_RS16700	COG1051	belongs to the nudix hydrolase family
SB85_RS16730	COG1090	epimerase
SB85_RS16740	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SB85_RS16745	COG0673	inositol 2-dehydrogenase activity
SB85_RS16750	COG2823	Periplasmic or secreted lipoprotein
SB85_RS16760	COG2205	protein histidine kinase activity
SB85_RS16765	COG0784	Response regulator, receiver
SB85_RS16770	COG4191	Histidine kinase
SB85_RS16780	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SB85_RS16785	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS16800	COG4305	rare lipoprotein A
SB85_RS16810	COG2188	Transcriptional regulator
SB85_RS16815	COG0738	Major facilitator superfamily
SB85_RS16820	COG1609	Transcriptional regulator
SB85_RS16825	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SB85_RS16830	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SB85_RS16875	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SB85_RS16885	COG2207	Transcriptional regulator
SB85_RS16890	COG0346	lactoylglutathione lyase activity
SB85_RS16905	COG2205	protein histidine kinase activity
SB85_RS16920	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SB85_RS16925	COG3791	Glutathione-dependent formaldehyde-activating
SB85_RS16935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SB85_RS16945	COG0697	spore germination
SB85_RS16955	COG1307	EDD domain protein, DegV family
SB85_RS16980	COG0804	urea catabolic process
SB85_RS16985	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SB85_RS16995	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SB85_RS17000	COG0726	polysaccharide deacetylase
SB85_RS17020	COG0436	Aminotransferase
SB85_RS17025	COG1162	GTPase activity
SB85_RS17050	COG2211	Major facilitator Superfamily
SB85_RS17060	COG1028	Short-chain dehydrogenase reductase Sdr
SB85_RS17065	COG2851	Citrate transporter
SB85_RS17080	COG0642	Histidine kinase
SB85_RS17090	COG2205	protein histidine kinase activity
SB85_RS17090	COG0745	RESPONSE REGULATOR receiver
SB85_RS17090	COG3292	Two component regulator propeller
SB85_RS17090	COG3292	Two component regulator propeller
SB85_RS17090	COG2205	protein histidine kinase activity
SB85_RS17090	COG0745	RESPONSE REGULATOR receiver
SB85_RS17110	COG2205	protein histidine kinase activity
SB85_RS17110	COG2198	Histidine kinase
SB85_RS17110	COG0784	Response regulator, receiver
SB85_RS17120	COG1301	dicarboxylic acid transport
SB85_RS17125	COG0281	malic enzyme
SB85_RS17125	COG0280	phosphate acetyltransferase
SB85_RS17170	COG1560	Kdo2-lipid A biosynthetic process
SB85_RS17175	COG1519	Transferase
SB85_RS17180	COG1538	Outer membrane efflux protein
SB85_RS17185	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SB85_RS17210	COG0300	oxidoreductase activity
SB85_RS17225	COG0642	Histidine kinase
SB85_RS17230	COG3706	GGDEF domain
SB85_RS17235	COG0473	3-isopropylmalate dehydrogenase activity
SB85_RS17255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SB85_RS17275	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SB85_RS17280	COG0405	Gamma-glutamyltransferase
SB85_RS17290	COG0840	transmembrane signaling receptor activity
SB85_RS17295	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SB85_RS17305	COG0823	Involved in the tonB-independent uptake of proteins
SB85_RS17305	COG1506	peptidase
SB85_RS17305	COG4946	Tricorn protease homolog
SB85_RS17325	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SB85_RS17335	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SB85_RS17360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SB85_RS17375	COG0586	Pfam SNARE associated Golgi protein
SB85_RS17400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SB85_RS17405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SB85_RS17415	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
SB85_RS17420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SB85_RS17430	COG1773	rubredoxin
SB85_RS17445	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SB85_RS17455	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SB85_RS17480	COG3079	Belongs to the UPF0149 family
SB85_RS17485	COG0006	proline dipeptidase activity
SB85_RS17495	COG0006	proline dipeptidase activity
SB85_RS17505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SB85_RS17515	COG0346	lactoylglutathione lyase activity
SB85_RS17520	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SB85_RS17525	COG1561	YicC-like family, N-terminal region
SB85_RS17535	COG0848	biopolymer transport protein
SB85_RS17545	COG2832	Protein of unknown function (DUF454)
SB85_RS17570	COG3712	iron ion homeostasis
SB85_RS17580	COG0194	GDP metabolic process
SB85_RS17585	COG1758	RNA polymerase activity
SB85_RS17590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SB85_RS17600	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SB85_RS17610	COG0254	rRNA binding
SB85_RS17625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SB85_RS17655	COG0714	Associated with various cellular activities
SB85_RS17685	COG1301	dicarboxylic acid transport
SB85_RS17695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SB85_RS17770	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SB85_RS17775	COG4149	molybdate abc transporter
SB85_RS17780	COG0725	ABC transporter, periplasmic molybdate-binding protein
SB85_RS17790	COG0640	Transcriptional regulator
SB85_RS17825	COG3047	cAMP biosynthetic process
SB85_RS17830	COG3047	cAMP biosynthetic process
SB85_RS17835	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SB85_RS17875	COG0469	pyruvate kinase activity
SB85_RS17885	COG3588	fructose-bisphosphate aldolase
SB85_RS17910	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SB85_RS17955	COG5002	protein histidine kinase activity
SB85_RS17960	COG1393	Belongs to the ArsC family
SB85_RS17980	COG0175	sulfate reduction
SB85_RS17985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SB85_RS17990	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SB85_RS17995	COG0175	sulfate reduction
SB85_RS18000	COG0529	Catalyzes the synthesis of activated sulfate
SB85_RS18000	COG2895	sulfate adenylyltransferase (ATP) activity
SB85_RS18005	COG0308	aminopeptidase N
SB85_RS18020	COG0438	transferase activity, transferring glycosyl groups
SB85_RS18040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SB85_RS18055	COG1609	Transcriptional regulator
SB85_RS18070	COG0179	Fumarylacetoacetate (FAA) hydrolase
SB85_RS18090	COG3273	potassium ion transport
SB85_RS18090	COG0471	metal ion transport
SB85_RS18125	COG3511	phospholipase C
SB85_RS18135	COG0189	ligase activity
SB85_RS18140	COG0745	RESPONSE REGULATOR receiver
SB85_RS18155	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SB85_RS18185	COG0045	succinate-CoA ligase (ADP-forming) activity
SB85_RS18190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SB85_RS18200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SB85_RS18200	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SB85_RS18205	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SB85_RS18210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SB85_RS18765	COG2198	Histidine kinase
SB85_RS18765	COG0643	Histidine kinase
SB85_RS18885	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SB85_RS19020	COG0837	glucose binding
SB85_RS19270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SB85_RS19695	COG2258	MOSC domain
SB85_RS19845	COG0318	PFAM AMP-dependent synthetase and ligase
SB85_RS19940	COG0840	transmembrane signaling receptor activity
SB85_RS20025	COG0840	transmembrane signaling receptor activity
SB85_RS20155	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SB85_RS20445	COG2201	protein-glutamate methylesterase activity
SB85_RS20450	COG3190	flagellar
SB85_RS20460	COG2205	protein histidine kinase activity
SB85_RS20475	COG3409	Peptidoglycan-binding domain 1 protein
SB85_RS20475	COG3773	Cell wall hydrolase
SB85_RS20565	COG2234	aminopeptidase activity